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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:C15orf41-LRRC28 (FusionGDB2 ID:HG84529TG123355)

Fusion Gene Summary for C15orf41-LRRC28

check button Fusion gene summary
Fusion gene informationFusion gene name: C15orf41-LRRC28
Fusion gene ID: hg84529tg123355
HgeneTgene
Gene symbol

C15orf41

LRRC28

Gene ID

84529

123355

Gene namechromosome 15 open reading frame 41leucine rich repeat containing 28
SynonymsHH114-
Cytomap('C15orf41')('LRRC28')

15q14

15q26.3

Type of geneprotein-codingprotein-coding
Descriptionprotein C15orf41uncharacterized protein C15orf41leucine-rich repeat-containing protein 28
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000437989, ENST00000566621, 
ENST00000569302, ENST00000338183, 
ENST00000562489, ENST00000562877, 
ENST00000563167, ENST00000565792, 
ENST00000567389, 
Fusion gene scores* DoF score13 X 6 X 8=62415 X 11 X 9=1485
# samples 1319
** MAII scorelog2(13/624*10)=-2.26303440583379
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(19/1485*10)=-2.96639160735718
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: C15orf41 [Title/Abstract] AND LRRC28 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointC15orf41(36872162)-LRRC28(99926235), # samples:1
Anticipated loss of major functional domain due to fusion event.C15orf41-LRRC28 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across C15orf41 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across LRRC28 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-D7-8576-01AC15orf41chr15

36872162

+LRRC28chr15

99926235

+


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Fusion Gene ORF analysis for C15orf41-LRRC28

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000437989ENST00000331450C15orf41chr15

36872162

+LRRC28chr15

99926235

+
5CDS-intronENST00000437989ENST00000442993C15orf41chr15

36872162

+LRRC28chr15

99926235

+
5CDS-intronENST00000437989ENST00000447360C15orf41chr15

36872162

+LRRC28chr15

99926235

+
5CDS-intronENST00000437989ENST00000559399C15orf41chr15

36872162

+LRRC28chr15

99926235

+
5CDS-intronENST00000566621ENST00000331450C15orf41chr15

36872162

+LRRC28chr15

99926235

+
5CDS-intronENST00000566621ENST00000442993C15orf41chr15

36872162

+LRRC28chr15

99926235

+
5CDS-intronENST00000566621ENST00000447360C15orf41chr15

36872162

+LRRC28chr15

99926235

+
5CDS-intronENST00000566621ENST00000559399C15orf41chr15

36872162

+LRRC28chr15

99926235

+
5CDS-intronENST00000569302ENST00000331450C15orf41chr15

36872162

+LRRC28chr15

99926235

+
5CDS-intronENST00000569302ENST00000442993C15orf41chr15

36872162

+LRRC28chr15

99926235

+
5CDS-intronENST00000569302ENST00000447360C15orf41chr15

36872162

+LRRC28chr15

99926235

+
5CDS-intronENST00000569302ENST00000559399C15orf41chr15

36872162

+LRRC28chr15

99926235

+
Frame-shiftENST00000437989ENST00000422500C15orf41chr15

36872162

+LRRC28chr15

99926235

+
Frame-shiftENST00000437989ENST00000558879C15orf41chr15

36872162

+LRRC28chr15

99926235

+
Frame-shiftENST00000566621ENST00000422500C15orf41chr15

36872162

+LRRC28chr15

99926235

+
Frame-shiftENST00000566621ENST00000558879C15orf41chr15

36872162

+LRRC28chr15

99926235

+
Frame-shiftENST00000569302ENST00000422500C15orf41chr15

36872162

+LRRC28chr15

99926235

+
Frame-shiftENST00000569302ENST00000558879C15orf41chr15

36872162

+LRRC28chr15

99926235

+
In-frameENST00000437989ENST00000301981C15orf41chr15

36872162

+LRRC28chr15

99926235

+
In-frameENST00000566621ENST00000301981C15orf41chr15

36872162

+LRRC28chr15

99926235

+
In-frameENST00000569302ENST00000301981C15orf41chr15

36872162

+LRRC28chr15

99926235

+
intron-3CDSENST00000338183ENST00000301981C15orf41chr15

36872162

+LRRC28chr15

99926235

+
intron-3CDSENST00000338183ENST00000422500C15orf41chr15

36872162

+LRRC28chr15

99926235

+
intron-3CDSENST00000338183ENST00000558879C15orf41chr15

36872162

+LRRC28chr15

99926235

+
intron-3CDSENST00000562489ENST00000301981C15orf41chr15

36872162

+LRRC28chr15

99926235

+
intron-3CDSENST00000562489ENST00000422500C15orf41chr15

36872162

+LRRC28chr15

99926235

+
intron-3CDSENST00000562489ENST00000558879C15orf41chr15

36872162

+LRRC28chr15

99926235

+
intron-3CDSENST00000562877ENST00000301981C15orf41chr15

36872162

+LRRC28chr15

99926235

+
intron-3CDSENST00000562877ENST00000422500C15orf41chr15

36872162

+LRRC28chr15

99926235

+
intron-3CDSENST00000562877ENST00000558879C15orf41chr15

36872162

+LRRC28chr15

99926235

+
intron-3CDSENST00000563167ENST00000301981C15orf41chr15

36872162

+LRRC28chr15

99926235

+
intron-3CDSENST00000563167ENST00000422500C15orf41chr15

36872162

+LRRC28chr15

99926235

+
intron-3CDSENST00000563167ENST00000558879C15orf41chr15

36872162

+LRRC28chr15

99926235

+
intron-3CDSENST00000565792ENST00000301981C15orf41chr15

36872162

+LRRC28chr15

99926235

+
intron-3CDSENST00000565792ENST00000422500C15orf41chr15

36872162

+LRRC28chr15

99926235

+
intron-3CDSENST00000565792ENST00000558879C15orf41chr15

36872162

+LRRC28chr15

99926235

+
intron-3CDSENST00000567389ENST00000301981C15orf41chr15

36872162

+LRRC28chr15

99926235

+
intron-3CDSENST00000567389ENST00000422500C15orf41chr15

36872162

+LRRC28chr15

99926235

+
intron-3CDSENST00000567389ENST00000558879C15orf41chr15

36872162

+LRRC28chr15

99926235

+
intron-intronENST00000338183ENST00000331450C15orf41chr15

36872162

+LRRC28chr15

99926235

+
intron-intronENST00000338183ENST00000442993C15orf41chr15

36872162

+LRRC28chr15

99926235

+
intron-intronENST00000338183ENST00000447360C15orf41chr15

36872162

+LRRC28chr15

99926235

+
intron-intronENST00000338183ENST00000559399C15orf41chr15

36872162

+LRRC28chr15

99926235

+
intron-intronENST00000562489ENST00000331450C15orf41chr15

36872162

+LRRC28chr15

99926235

+
intron-intronENST00000562489ENST00000442993C15orf41chr15

36872162

+LRRC28chr15

99926235

+
intron-intronENST00000562489ENST00000447360C15orf41chr15

36872162

+LRRC28chr15

99926235

+
intron-intronENST00000562489ENST00000559399C15orf41chr15

36872162

+LRRC28chr15

99926235

+
intron-intronENST00000562877ENST00000331450C15orf41chr15

36872162

+LRRC28chr15

99926235

+
intron-intronENST00000562877ENST00000442993C15orf41chr15

36872162

+LRRC28chr15

99926235

+
intron-intronENST00000562877ENST00000447360C15orf41chr15

36872162

+LRRC28chr15

99926235

+
intron-intronENST00000562877ENST00000559399C15orf41chr15

36872162

+LRRC28chr15

99926235

+
intron-intronENST00000563167ENST00000331450C15orf41chr15

36872162

+LRRC28chr15

99926235

+
intron-intronENST00000563167ENST00000442993C15orf41chr15

36872162

+LRRC28chr15

99926235

+
intron-intronENST00000563167ENST00000447360C15orf41chr15

36872162

+LRRC28chr15

99926235

+
intron-intronENST00000563167ENST00000559399C15orf41chr15

36872162

+LRRC28chr15

99926235

+
intron-intronENST00000565792ENST00000331450C15orf41chr15

36872162

+LRRC28chr15

99926235

+
intron-intronENST00000565792ENST00000442993C15orf41chr15

36872162

+LRRC28chr15

99926235

+
intron-intronENST00000565792ENST00000447360C15orf41chr15

36872162

+LRRC28chr15

99926235

+
intron-intronENST00000565792ENST00000559399C15orf41chr15

36872162

+LRRC28chr15

99926235

+
intron-intronENST00000567389ENST00000331450C15orf41chr15

36872162

+LRRC28chr15

99926235

+
intron-intronENST00000567389ENST00000442993C15orf41chr15

36872162

+LRRC28chr15

99926235

+
intron-intronENST00000567389ENST00000447360C15orf41chr15

36872162

+LRRC28chr15

99926235

+
intron-intronENST00000567389ENST00000559399C15orf41chr15

36872162

+LRRC28chr15

99926235

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)
BP loci
(transcript)
Predicted start
(transcript)
Predicted stop
(transcript)
Seq length
(amino acids)
ENST00000566621C15orf41chr1536872162+ENST00000301981LRRC28chr1599926235+5051351118423101
ENST00000437989C15orf41chr1536872162+ENST00000301981LRRC28chr1599926235+48181184081438099
ENST00000569302C15orf41chr1536872162+ENST00000301981LRRC28chr1599926235+48141144077437699

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000566621ENST00000301981C15orf41chr1536872162+LRRC28chr1599926235+0.809791560.19020845
ENST00000437989ENST00000301981C15orf41chr1536872162+LRRC28chr1599926235+0.79829970.20170029
ENST00000569302ENST00000301981C15orf41chr1536872162+LRRC28chr1599926235+0.79652080.20347917

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Fusion Genomic Features for C15orf41-LRRC28


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
C15orf41chr1536872162+LRRC28chr1599926234+1.22E-060.9999988
C15orf41chr1536872162+LRRC28chr1599926234+1.22E-060.9999988

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for C15orf41-LRRC28


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr15:36872162/chr15:99926235)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneLRRC28chr15:36872162chr15:99926235ENST00000301981810112_133343368.0RepeatNote=LRR 5
TgeneLRRC28chr15:36872162chr15:99926235ENST00000301981810135_156343368.0RepeatNote=LRR 6
TgeneLRRC28chr15:36872162chr15:99926235ENST00000301981810158_180343368.0RepeatNote=LRR 7
TgeneLRRC28chr15:36872162chr15:99926235ENST0000030198181016_36343368.0RepeatNote=LRR 1
TgeneLRRC28chr15:36872162chr15:99926235ENST00000301981810181_202343368.0RepeatNote=LRR 8
TgeneLRRC28chr15:36872162chr15:99926235ENST00000301981810204_226343368.0RepeatNote=LRR 9
TgeneLRRC28chr15:36872162chr15:99926235ENST0000030198181042_63343368.0RepeatNote=LRR 2
TgeneLRRC28chr15:36872162chr15:99926235ENST0000030198181066_87343368.0RepeatNote=LRR 3
TgeneLRRC28chr15:36872162chr15:99926235ENST0000030198181089_110343368.0RepeatNote=LRR 4
TgeneLRRC28chr15:36872162chr15:99926235ENST0000044736079112_133290313.0RepeatNote=LRR 5
TgeneLRRC28chr15:36872162chr15:99926235ENST0000044736079135_156290313.0RepeatNote=LRR 6
TgeneLRRC28chr15:36872162chr15:99926235ENST0000044736079158_180290313.0RepeatNote=LRR 7
TgeneLRRC28chr15:36872162chr15:99926235ENST000004473607916_36290313.0RepeatNote=LRR 1
TgeneLRRC28chr15:36872162chr15:99926235ENST0000044736079181_202290313.0RepeatNote=LRR 8
TgeneLRRC28chr15:36872162chr15:99926235ENST0000044736079204_226290313.0RepeatNote=LRR 9
TgeneLRRC28chr15:36872162chr15:99926235ENST000004473607942_63290313.0RepeatNote=LRR 2
TgeneLRRC28chr15:36872162chr15:99926235ENST000004473607966_87290313.0RepeatNote=LRR 3
TgeneLRRC28chr15:36872162chr15:99926235ENST000004473607989_110290313.0RepeatNote=LRR 4


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Fusion Gene Sequence for C15orf41-LRRC28


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>10951_10951_1_C15orf41-LRRC28_C15orf41_chr15_36872162_ENST00000437989_LRRC28_chr15_99926235_ENST00000301981_length(transcript)=4818nt_BP=118nt
CTGGTCCCTGGCCCAACATGATACTGACCAAAGCTCAGTACGACGAGATAGCCCAGTGCCTAGTGTCTGTGCCGCCTACCAGGCAGAGCC
TGAGGAAGCTGAAGCAGAGGTTTCCCAGGAAGACAACTGTTAGTTTTGTGGCTTACTGCTGCTCCACCCAGTGTCTGCAGACTTTTGACC
TGCTGAGTTGATAAACACTCAAGAACCTCAGGAGCGCTGCCAGCTTGACACTGGGGAATCCAGCCAGTCCAGCACACTCTTCCATCCTGT
CCTGTCCAATGCGGGGGCACTGCAGAACTCTCTAGAAATGTCATGATTGAGCTTCAGAGCTAAAATGCCTTCACCCTTCCCCCAAGTTGG
AATATATCCTCCCCCAAATTAAGGACCCATTTGTCTTCTGTGTTTTTCCTTTTTATGTGAGTGTGTCTTTTACAGAAACCATTTAGATTG
ATGGGCCTCCCCAAATCTAATTTAAAGCAAGTTTCCGGTCCTTGGAGAACAGTGACTTGATCATCTAGCCAGATTCCCTTTTGAACACAC
ATACCTTCAGTGATGCTTCCTCTCCTCTCCCCTCCCTTGCTTTCCCCAGAGAGTTATTTCCCTGAGACCATGTTCTCCACAGTGTCTCCA
GTGGAAACTTGTCAGTTTTTGAGGAGTTTCAGCAAACCCCGTGGCCTCAATGGTCTTGAGTAGCAGGGTGGGGCGCCTGAGTTGGCAGCA
AAGTGAGGCTCCCATGGAGGCTCAGTGAGGGTCCCAGAGCACACACCCTCTGGAAAGTTCCAGCCTTGTTTATACGTTCTACAGTGTAGC
AACAGACTTTTGTGAGGGATTTTAAAAACAAAAATGTAGATTGTAATGAAATACACTTCCTGTTTTTTAAAAGTGTTTGCAGAAAAATGA
TTTTTGAAGTTTTTAAATTTCCTGATAAGATTTTTTTTATATGAGAAGAATTTGAGGAATATTTGAAGCTTTACAAGATCTGATTTTTTT
CTTTCTCAATATAAAGTTTCCATACAATGAGAAAGGGGGAGAAAACACACATTGAAATAAGACCTCCGTGTTCTTTTTTGATGGGTTTAT
GATTCAGTTTATACTGACTTTGAAATATTTTTGTCACATGTGAAAGGCTTCAGCTACTTCCACTACTGGTTTTTTTTTGTTGTTGTTGAG
ACGGAGTCTCGCTCTGTCGCCCAGGCTGGAGTGCAGTGGCGGGATCTCGGCTCACTGCAAGCTCCGCCTCCCGGGTTCACGCCATTCTCC
TGCCTCAGCCTCCCAAGTAGCTGGGACCACAGGCGCCCGCCACCACGCCCGGCTAATTTTTTGTATTTTTAGTAGAGACGGGGTTTCACC
GTGTTAGCCGGGATGGTCTCGATCTCCTGACCTCGTGATCCGCACGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGC
GCCCGGCCCACTACTGGTTTTTAACAGGATGATTCAAAGTACAGCCCGTGCACATTTACTTCGTCACCTGGTGCACCACACTGTCTTCAT
GTTGGCCCTCGTTTCTTGTATACTTAGCTTACTGCCCAGATGCAACTGAGAAAATACAGGAAAAGCAGGTCCAAATTCAGCCTTCGACTT
CTGCAAAAGTCCATAAACAGAAAGTCTGTGAGCCTCCACCCTGCCAGAAAGAACTCTTCATGAAGAAGTCACGTATTTGCTCTTCCTTTC
AAAGGATGGCATTTTAATGTTGCTTTGCTGCCAGATGTTCATCTGCTTGCTGTGAAGTGATTCTTTTTTTAAAATGTTTTTTAATGATGT
AAGTTTTCTAAAAGGCAGGGCTGAATGGAGAACCAAGAATTTGCTTGGTAGAAAAATTATTTTTTTTTAATTTCAGACTTATCAAAAATT
TGGTTGAGGGAATTTTTATTAGCTGCCCTGACTTTATAATGCTACGCTCTTAACAGTGCCAAAAATCCTACATAGTTACTGACAAATGTG
TGATCTTTTTACAGTCACAACACCTGCTGCCCGGAAAGCACACCGTCCACGTAGAATGGAGAAGGCAGAAAGTTACCGTGTGTTCCCACT
GTATCTGCACTGTTCTTACTTCCTCTTGTCCCTTTTCATATCTTGGTCTATTCAGCCTTAACATTTCAAAGGCTTATAGTAAAATAGGAA
CTGAAGATCTGTATCAAAATGTAACACTTTCATCCTTTGGAATAATTGAAGTTTAACATAACCTCTACATGTATATAAGTTAGCTGGTGA
AAATGTGGCATGAAACTTCACAATTGTGCTTCAGGCCTAAGTGACTGCTACCTATGATTTAAGTGACAGTAAATGTCTTGCTACATTTTT
CTATTTCATCCTCTACAATCATATGTCATGGAATGGAGCTATGAAATGTGCTAACTTGGTATTCAGGATTCTCATTGTGATAAGGTGATA
CATTAGTTTTACCTTGTTTGAAATTTTACAAAAATGCTTACAATCCAGGCATTCTTTCTCTACCTATTATGAACTACGGTGTGTTAAACA
ACAGCAGTGGGCTGGGCAGACAACCTTTGGGCAGTCTCAACCTTAATCCTTGGGTACAGCACCTGAACTTAATTGATGAGAAGTGGAACT
TAAGTGGTTTCCCTGGTGCTGTTCATTATGGAAATTTTATGCTGGATTTATCGATGTCATTCTTAATCTTTTGATACTATAAAGGAGTCT
TACCAACTGGAGAAAATTTGCCTACATGCTATATATTTGAATTGTGTCCAAAGCTTTGCAGAAAAGCAAATCTGAAGTTATTATATATGT
TGTTTTCTTGAGCAACAGTTACACTAGGTAGAAAAGTATTCACACAATAATAGTAATGCAAAAAAAGTGAGCTACTTGGAAAGTATCATC
TCTGTTCAGGTAAGTTTACTTCAGTGAACTCTTGTGTGGTTAGCGATAAGTTTTAAAGTCCAGGATAGCCTCATGAGCATAGGCCTTCCT
ATGAAGTAGTGCAAAGGGGGCCGATTTTAGTGGATTACCCTATCAGTGTTCTTCAGTATGTCCAATTGTTATCATACCAAAAACCTTAAT
TACATAACATTGTGTGGATGAAATGCTGCATCTTCAGTTAATACATGTTTTGAGCACATTCTTAAAATACATAATAATTAAATGATCCCT
ATTCAAAAGAACCCTGGCTTGGGTGGAGGATCCACTCTGGCTAACGGATAAGAGTGATGAACTTCTTTGTTACCTGACCCTTCTCTTCTG
GAAAAGTGAGGTGTACATTAAACATCTTTTGGTCACCGTGCCTCACTAAGACCTTTCACATTCCAGCTTGTCCGACTAGTGTAATGTACC
TCTCACTTCTGTTTTACGTTGAGCATTACGAATTAAAATCTTTACAGTCTAGGGGGAAAAAAAGGCTTCAATACCAGTTGGCTTATGAGG
CTCTGCATATAATTTTCTCTAAAATATGTAACTATTTTGTAGTCTGTGGGGACTTTCAAAGCCAATTTTTAAAATTAGTAGTAGTAAAGG
TTTTTCCCTTTCCTGAATGAAAAATCAGAAATTCTAATCTTTGCTATAAAGTACTTAAACACAATACATTGCCTCAGCATAAATAAAAAC
ATTTTTATTAAGATGATTTATGAACATGGATTTCTAACTGGACCAACACTAATGTTGCAACCTGATAAAATTTGAGATGTAAATTCATTT
CACAGACTCATAAACACACTCTCTTTAAGACTCTTCTTTAAATGGATCCTTACATTACCCTGCCTGTTTTATTATGCCTTCATTTTTGTG
GTTTTCATTCACTCCTGCTTGCTTCTATTGAGGTTCTCCTACATTTCCCAGAAACTCAGTGAATATCTTGCCTTTTCTTCAAACAAAGGG
GGTTTTTATAAAGTTTGTATTTTTGAAACTAGCTCTATGTCTATCTAAAAATCAAGTCTCGGCAGTGGCTCATGCCTATAATCCCAGCAC
TTTGGGAGGCCGAGGAGGGCAGATCATCTGAGGTCAGGAGTTTGAGACCAGCCTGGCCAGCATGGTGAAACCCCATCTCTACTAAAAATA
CAAAAAATTAGCCAGGCGTGGTGGCGCGCACCTGCAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATTGCTTGAACCCGGCAGGAAG
AGGTTGCATTGAGCTGAGATCACGCCATTACACTCCAGCCTGGGCAACAGAGCGAGACTCCGTCTCAAAAAAAAATCATTCAAGTTTCAC
TGTGCCTACAGTGAGGAGCTACCTCCTTGTGTCATCAGCTAATAGATCTGAAAGTGATGCCGGTGTCTCTAGGAAAGGAATTGATCATAG
CCAAGTGACTGACATTCTCTCGGTCAGGAAAAGAGCTTGCTTCACAGCCTTTGAAGTATGACTGTATGTGTGGTCCCCTTGTACTTTGGA
GACAGAAGGTACTGGCAGCGAGTGTGGTGGATGGGCAGAAGGTGTAGCATTCGGAGATTATTTCTGTATGTAATTAAGAGACTTTCAAGG
GTTAGCCAGACTTTTTTCCACTCAAGTGTGGATTATCTTTGCTACCTGTGTTAAAGAATATCAGGTTTTGTTTCTTATTGTGATTTTTGA
GTCTAAATGATCCAAGATTTTTAAAATAGATACATAATGAAATCCAGGCCTCTGAAAAATTATGGCAACATTCATTTGGAGTGTGGCTAA
AAACTCATACTTTATCCAATTTGGTTGCCTCTCTCAGTTACTGCAGTTTATAGAATAATTGAGCTTGAACCATGTGAATGCTCAGAATGT

>10951_10951_1_C15orf41-LRRC28_C15orf41_chr15_36872162_ENST00000437989_LRRC28_chr15_99926235_ENST00000301981_length(amino acids)=99AA_BP=
MQSQLLGRLRQENCLNPAGRGCIELRSRHYTPAWATERDSVSKKNHSSFTVPTVRSYLLVSSANRSESDAGVSRKGIDHSQVTDILSVRK

--------------------------------------------------------------
>10951_10951_2_C15orf41-LRRC28_C15orf41_chr15_36872162_ENST00000566621_LRRC28_chr15_99926235_ENST00000301981_length(transcript)=5051nt_BP=351nt
AAGCCAAGCTAGGGCACTCTGGTGTACAGCCAGTCCCCGCCGCGGAGGTGCCGGTGGAGCCTGGGACCGGGCGAGTCTCCGCCCCGCTTT
TGCAGCTAGGGGTGTGTTTCAGGGGGGATTGGGGCAAGCCAAGCAGGCGAGGACCCGGGCCTGTGCCGCTTTGCCTACCCCTCATCCCTC
GGCACCAAGGCTACTTGAGCCCCAGGGTGTTTTTTCCTTGTTCCCGCCACCTCCTGGTCCCTGGCCCAACATGATACTGACCAAAGCTCA
GTACGACGAGATAGCCCAGTGCCTAGTGTCTGTGCCGCCTACCAGGCAGAGCCTGAGGAAGCTGAAGCAGAGGTTTCCCAGGAAGACAAC
TGTTAGTTTTGTGGCTTACTGCTGCTCCACCCAGTGTCTGCAGACTTTTGACCTGCTGAGTTGATAAACACTCAAGAACCTCAGGAGCGC
TGCCAGCTTGACACTGGGGAATCCAGCCAGTCCAGCACACTCTTCCATCCTGTCCTGTCCAATGCGGGGGCACTGCAGAACTCTCTAGAA
ATGTCATGATTGAGCTTCAGAGCTAAAATGCCTTCACCCTTCCCCCAAGTTGGAATATATCCTCCCCCAAATTAAGGACCCATTTGTCTT
CTGTGTTTTTCCTTTTTATGTGAGTGTGTCTTTTACAGAAACCATTTAGATTGATGGGCCTCCCCAAATCTAATTTAAAGCAAGTTTCCG
GTCCTTGGAGAACAGTGACTTGATCATCTAGCCAGATTCCCTTTTGAACACACATACCTTCAGTGATGCTTCCTCTCCTCTCCCCTCCCT
TGCTTTCCCCAGAGAGTTATTTCCCTGAGACCATGTTCTCCACAGTGTCTCCAGTGGAAACTTGTCAGTTTTTGAGGAGTTTCAGCAAAC
CCCGTGGCCTCAATGGTCTTGAGTAGCAGGGTGGGGCGCCTGAGTTGGCAGCAAAGTGAGGCTCCCATGGAGGCTCAGTGAGGGTCCCAG
AGCACACACCCTCTGGAAAGTTCCAGCCTTGTTTATACGTTCTACAGTGTAGCAACAGACTTTTGTGAGGGATTTTAAAAACAAAAATGT
AGATTGTAATGAAATACACTTCCTGTTTTTTAAAAGTGTTTGCAGAAAAATGATTTTTGAAGTTTTTAAATTTCCTGATAAGATTTTTTT
TATATGAGAAGAATTTGAGGAATATTTGAAGCTTTACAAGATCTGATTTTTTTCTTTCTCAATATAAAGTTTCCATACAATGAGAAAGGG
GGAGAAAACACACATTGAAATAAGACCTCCGTGTTCTTTTTTGATGGGTTTATGATTCAGTTTATACTGACTTTGAAATATTTTTGTCAC
ATGTGAAAGGCTTCAGCTACTTCCACTACTGGTTTTTTTTTGTTGTTGTTGAGACGGAGTCTCGCTCTGTCGCCCAGGCTGGAGTGCAGT
GGCGGGATCTCGGCTCACTGCAAGCTCCGCCTCCCGGGTTCACGCCATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGACCACAGGCGCC
CGCCACCACGCCCGGCTAATTTTTTGTATTTTTAGTAGAGACGGGGTTTCACCGTGTTAGCCGGGATGGTCTCGATCTCCTGACCTCGTG
ATCCGCACGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCGCCCGGCCCACTACTGGTTTTTAACAGGATGATTCAA
AGTACAGCCCGTGCACATTTACTTCGTCACCTGGTGCACCACACTGTCTTCATGTTGGCCCTCGTTTCTTGTATACTTAGCTTACTGCCC
AGATGCAACTGAGAAAATACAGGAAAAGCAGGTCCAAATTCAGCCTTCGACTTCTGCAAAAGTCCATAAACAGAAAGTCTGTGAGCCTCC
ACCCTGCCAGAAAGAACTCTTCATGAAGAAGTCACGTATTTGCTCTTCCTTTCAAAGGATGGCATTTTAATGTTGCTTTGCTGCCAGATG
TTCATCTGCTTGCTGTGAAGTGATTCTTTTTTTAAAATGTTTTTTAATGATGTAAGTTTTCTAAAAGGCAGGGCTGAATGGAGAACCAAG
AATTTGCTTGGTAGAAAAATTATTTTTTTTTAATTTCAGACTTATCAAAAATTTGGTTGAGGGAATTTTTATTAGCTGCCCTGACTTTAT
AATGCTACGCTCTTAACAGTGCCAAAAATCCTACATAGTTACTGACAAATGTGTGATCTTTTTACAGTCACAACACCTGCTGCCCGGAAA
GCACACCGTCCACGTAGAATGGAGAAGGCAGAAAGTTACCGTGTGTTCCCACTGTATCTGCACTGTTCTTACTTCCTCTTGTCCCTTTTC
ATATCTTGGTCTATTCAGCCTTAACATTTCAAAGGCTTATAGTAAAATAGGAACTGAAGATCTGTATCAAAATGTAACACTTTCATCCTT
TGGAATAATTGAAGTTTAACATAACCTCTACATGTATATAAGTTAGCTGGTGAAAATGTGGCATGAAACTTCACAATTGTGCTTCAGGCC
TAAGTGACTGCTACCTATGATTTAAGTGACAGTAAATGTCTTGCTACATTTTTCTATTTCATCCTCTACAATCATATGTCATGGAATGGA
GCTATGAAATGTGCTAACTTGGTATTCAGGATTCTCATTGTGATAAGGTGATACATTAGTTTTACCTTGTTTGAAATTTTACAAAAATGC
TTACAATCCAGGCATTCTTTCTCTACCTATTATGAACTACGGTGTGTTAAACAACAGCAGTGGGCTGGGCAGACAACCTTTGGGCAGTCT
CAACCTTAATCCTTGGGTACAGCACCTGAACTTAATTGATGAGAAGTGGAACTTAAGTGGTTTCCCTGGTGCTGTTCATTATGGAAATTT
TATGCTGGATTTATCGATGTCATTCTTAATCTTTTGATACTATAAAGGAGTCTTACCAACTGGAGAAAATTTGCCTACATGCTATATATT
TGAATTGTGTCCAAAGCTTTGCAGAAAAGCAAATCTGAAGTTATTATATATGTTGTTTTCTTGAGCAACAGTTACACTAGGTAGAAAAGT
ATTCACACAATAATAGTAATGCAAAAAAAGTGAGCTACTTGGAAAGTATCATCTCTGTTCAGGTAAGTTTACTTCAGTGAACTCTTGTGT
GGTTAGCGATAAGTTTTAAAGTCCAGGATAGCCTCATGAGCATAGGCCTTCCTATGAAGTAGTGCAAAGGGGGCCGATTTTAGTGGATTA
CCCTATCAGTGTTCTTCAGTATGTCCAATTGTTATCATACCAAAAACCTTAATTACATAACATTGTGTGGATGAAATGCTGCATCTTCAG
TTAATACATGTTTTGAGCACATTCTTAAAATACATAATAATTAAATGATCCCTATTCAAAAGAACCCTGGCTTGGGTGGAGGATCCACTC
TGGCTAACGGATAAGAGTGATGAACTTCTTTGTTACCTGACCCTTCTCTTCTGGAAAAGTGAGGTGTACATTAAACATCTTTTGGTCACC
GTGCCTCACTAAGACCTTTCACATTCCAGCTTGTCCGACTAGTGTAATGTACCTCTCACTTCTGTTTTACGTTGAGCATTACGAATTAAA
ATCTTTACAGTCTAGGGGGAAAAAAAGGCTTCAATACCAGTTGGCTTATGAGGCTCTGCATATAATTTTCTCTAAAATATGTAACTATTT
TGTAGTCTGTGGGGACTTTCAAAGCCAATTTTTAAAATTAGTAGTAGTAAAGGTTTTTCCCTTTCCTGAATGAAAAATCAGAAATTCTAA
TCTTTGCTATAAAGTACTTAAACACAATACATTGCCTCAGCATAAATAAAAACATTTTTATTAAGATGATTTATGAACATGGATTTCTAA
CTGGACCAACACTAATGTTGCAACCTGATAAAATTTGAGATGTAAATTCATTTCACAGACTCATAAACACACTCTCTTTAAGACTCTTCT
TTAAATGGATCCTTACATTACCCTGCCTGTTTTATTATGCCTTCATTTTTGTGGTTTTCATTCACTCCTGCTTGCTTCTATTGAGGTTCT
CCTACATTTCCCAGAAACTCAGTGAATATCTTGCCTTTTCTTCAAACAAAGGGGGTTTTTATAAAGTTTGTATTTTTGAAACTAGCTCTA
TGTCTATCTAAAAATCAAGTCTCGGCAGTGGCTCATGCCTATAATCCCAGCACTTTGGGAGGCCGAGGAGGGCAGATCATCTGAGGTCAG
GAGTTTGAGACCAGCCTGGCCAGCATGGTGAAACCCCATCTCTACTAAAAATACAAAAAATTAGCCAGGCGTGGTGGCGCGCACCTGCAG
TCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATTGCTTGAACCCGGCAGGAAGAGGTTGCATTGAGCTGAGATCACGCCATTACACTCCA
GCCTGGGCAACAGAGCGAGACTCCGTCTCAAAAAAAAATCATTCAAGTTTCACTGTGCCTACAGTGAGGAGCTACCTCCTTGTGTCATCA
GCTAATAGATCTGAAAGTGATGCCGGTGTCTCTAGGAAAGGAATTGATCATAGCCAAGTGACTGACATTCTCTCGGTCAGGAAAAGAGCT
TGCTTCACAGCCTTTGAAGTATGACTGTATGTGTGGTCCCCTTGTACTTTGGAGACAGAAGGTACTGGCAGCGAGTGTGGTGGATGGGCA
GAAGGTGTAGCATTCGGAGATTATTTCTGTATGTAATTAAGAGACTTTCAAGGGTTAGCCAGACTTTTTTCCACTCAAGTGTGGATTATC
TTTGCTACCTGTGTTAAAGAATATCAGGTTTTGTTTCTTATTGTGATTTTTGAGTCTAAATGATCCAAGATTTTTAAAATAGATACATAA
TGAAATCCAGGCCTCTGAAAAATTATGGCAACATTCATTTGGAGTGTGGCTAAAAACTCATACTTTATCCAATTTGGTTGCCTCTCTCAG
TTACTGCAGTTTATAGAATAATTGAGCTTGAACCATGTGAATGCTCAGAATGTCAATGGTGGAGTATTTATTCAAGAGAAATGGCTGAAT

>10951_10951_2_C15orf41-LRRC28_C15orf41_chr15_36872162_ENST00000566621_LRRC28_chr15_99926235_ENST00000301981_length(amino acids)=101AA_BP=77
MGQAKQARTRACAALPTPHPSAPRLLEPQGVFSLFPPPPGPWPNMILTKAQYDEIAQCLVSVPPTRQSLRKLKQRFPRKTTVSFVAYCCS

--------------------------------------------------------------
>10951_10951_3_C15orf41-LRRC28_C15orf41_chr15_36872162_ENST00000569302_LRRC28_chr15_99926235_ENST00000301981_length(transcript)=4814nt_BP=114nt
TCCCTGGCCCAACATGATACTGACCAAAGCTCAGTACGACGAGATAGCCCAGTGCCTAGTGTCTGTGCCGCCTACCAGGCAGAGCCTGAG
GAAGCTGAAGCAGAGGTTTCCCAGGAAGACAACTGTTAGTTTTGTGGCTTACTGCTGCTCCACCCAGTGTCTGCAGACTTTTGACCTGCT
GAGTTGATAAACACTCAAGAACCTCAGGAGCGCTGCCAGCTTGACACTGGGGAATCCAGCCAGTCCAGCACACTCTTCCATCCTGTCCTG
TCCAATGCGGGGGCACTGCAGAACTCTCTAGAAATGTCATGATTGAGCTTCAGAGCTAAAATGCCTTCACCCTTCCCCCAAGTTGGAATA
TATCCTCCCCCAAATTAAGGACCCATTTGTCTTCTGTGTTTTTCCTTTTTATGTGAGTGTGTCTTTTACAGAAACCATTTAGATTGATGG
GCCTCCCCAAATCTAATTTAAAGCAAGTTTCCGGTCCTTGGAGAACAGTGACTTGATCATCTAGCCAGATTCCCTTTTGAACACACATAC
CTTCAGTGATGCTTCCTCTCCTCTCCCCTCCCTTGCTTTCCCCAGAGAGTTATTTCCCTGAGACCATGTTCTCCACAGTGTCTCCAGTGG
AAACTTGTCAGTTTTTGAGGAGTTTCAGCAAACCCCGTGGCCTCAATGGTCTTGAGTAGCAGGGTGGGGCGCCTGAGTTGGCAGCAAAGT
GAGGCTCCCATGGAGGCTCAGTGAGGGTCCCAGAGCACACACCCTCTGGAAAGTTCCAGCCTTGTTTATACGTTCTACAGTGTAGCAACA
GACTTTTGTGAGGGATTTTAAAAACAAAAATGTAGATTGTAATGAAATACACTTCCTGTTTTTTAAAAGTGTTTGCAGAAAAATGATTTT
TGAAGTTTTTAAATTTCCTGATAAGATTTTTTTTATATGAGAAGAATTTGAGGAATATTTGAAGCTTTACAAGATCTGATTTTTTTCTTT
CTCAATATAAAGTTTCCATACAATGAGAAAGGGGGAGAAAACACACATTGAAATAAGACCTCCGTGTTCTTTTTTGATGGGTTTATGATT
CAGTTTATACTGACTTTGAAATATTTTTGTCACATGTGAAAGGCTTCAGCTACTTCCACTACTGGTTTTTTTTTGTTGTTGTTGAGACGG
AGTCTCGCTCTGTCGCCCAGGCTGGAGTGCAGTGGCGGGATCTCGGCTCACTGCAAGCTCCGCCTCCCGGGTTCACGCCATTCTCCTGCC
TCAGCCTCCCAAGTAGCTGGGACCACAGGCGCCCGCCACCACGCCCGGCTAATTTTTTGTATTTTTAGTAGAGACGGGGTTTCACCGTGT
TAGCCGGGATGGTCTCGATCTCCTGACCTCGTGATCCGCACGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCGCCC
GGCCCACTACTGGTTTTTAACAGGATGATTCAAAGTACAGCCCGTGCACATTTACTTCGTCACCTGGTGCACCACACTGTCTTCATGTTG
GCCCTCGTTTCTTGTATACTTAGCTTACTGCCCAGATGCAACTGAGAAAATACAGGAAAAGCAGGTCCAAATTCAGCCTTCGACTTCTGC
AAAAGTCCATAAACAGAAAGTCTGTGAGCCTCCACCCTGCCAGAAAGAACTCTTCATGAAGAAGTCACGTATTTGCTCTTCCTTTCAAAG
GATGGCATTTTAATGTTGCTTTGCTGCCAGATGTTCATCTGCTTGCTGTGAAGTGATTCTTTTTTTAAAATGTTTTTTAATGATGTAAGT
TTTCTAAAAGGCAGGGCTGAATGGAGAACCAAGAATTTGCTTGGTAGAAAAATTATTTTTTTTTAATTTCAGACTTATCAAAAATTTGGT
TGAGGGAATTTTTATTAGCTGCCCTGACTTTATAATGCTACGCTCTTAACAGTGCCAAAAATCCTACATAGTTACTGACAAATGTGTGAT
CTTTTTACAGTCACAACACCTGCTGCCCGGAAAGCACACCGTCCACGTAGAATGGAGAAGGCAGAAAGTTACCGTGTGTTCCCACTGTAT
CTGCACTGTTCTTACTTCCTCTTGTCCCTTTTCATATCTTGGTCTATTCAGCCTTAACATTTCAAAGGCTTATAGTAAAATAGGAACTGA
AGATCTGTATCAAAATGTAACACTTTCATCCTTTGGAATAATTGAAGTTTAACATAACCTCTACATGTATATAAGTTAGCTGGTGAAAAT
GTGGCATGAAACTTCACAATTGTGCTTCAGGCCTAAGTGACTGCTACCTATGATTTAAGTGACAGTAAATGTCTTGCTACATTTTTCTAT
TTCATCCTCTACAATCATATGTCATGGAATGGAGCTATGAAATGTGCTAACTTGGTATTCAGGATTCTCATTGTGATAAGGTGATACATT
AGTTTTACCTTGTTTGAAATTTTACAAAAATGCTTACAATCCAGGCATTCTTTCTCTACCTATTATGAACTACGGTGTGTTAAACAACAG
CAGTGGGCTGGGCAGACAACCTTTGGGCAGTCTCAACCTTAATCCTTGGGTACAGCACCTGAACTTAATTGATGAGAAGTGGAACTTAAG
TGGTTTCCCTGGTGCTGTTCATTATGGAAATTTTATGCTGGATTTATCGATGTCATTCTTAATCTTTTGATACTATAAAGGAGTCTTACC
AACTGGAGAAAATTTGCCTACATGCTATATATTTGAATTGTGTCCAAAGCTTTGCAGAAAAGCAAATCTGAAGTTATTATATATGTTGTT
TTCTTGAGCAACAGTTACACTAGGTAGAAAAGTATTCACACAATAATAGTAATGCAAAAAAAGTGAGCTACTTGGAAAGTATCATCTCTG
TTCAGGTAAGTTTACTTCAGTGAACTCTTGTGTGGTTAGCGATAAGTTTTAAAGTCCAGGATAGCCTCATGAGCATAGGCCTTCCTATGA
AGTAGTGCAAAGGGGGCCGATTTTAGTGGATTACCCTATCAGTGTTCTTCAGTATGTCCAATTGTTATCATACCAAAAACCTTAATTACA
TAACATTGTGTGGATGAAATGCTGCATCTTCAGTTAATACATGTTTTGAGCACATTCTTAAAATACATAATAATTAAATGATCCCTATTC
AAAAGAACCCTGGCTTGGGTGGAGGATCCACTCTGGCTAACGGATAAGAGTGATGAACTTCTTTGTTACCTGACCCTTCTCTTCTGGAAA
AGTGAGGTGTACATTAAACATCTTTTGGTCACCGTGCCTCACTAAGACCTTTCACATTCCAGCTTGTCCGACTAGTGTAATGTACCTCTC
ACTTCTGTTTTACGTTGAGCATTACGAATTAAAATCTTTACAGTCTAGGGGGAAAAAAAGGCTTCAATACCAGTTGGCTTATGAGGCTCT
GCATATAATTTTCTCTAAAATATGTAACTATTTTGTAGTCTGTGGGGACTTTCAAAGCCAATTTTTAAAATTAGTAGTAGTAAAGGTTTT
TCCCTTTCCTGAATGAAAAATCAGAAATTCTAATCTTTGCTATAAAGTACTTAAACACAATACATTGCCTCAGCATAAATAAAAACATTT
TTATTAAGATGATTTATGAACATGGATTTCTAACTGGACCAACACTAATGTTGCAACCTGATAAAATTTGAGATGTAAATTCATTTCACA
GACTCATAAACACACTCTCTTTAAGACTCTTCTTTAAATGGATCCTTACATTACCCTGCCTGTTTTATTATGCCTTCATTTTTGTGGTTT
TCATTCACTCCTGCTTGCTTCTATTGAGGTTCTCCTACATTTCCCAGAAACTCAGTGAATATCTTGCCTTTTCTTCAAACAAAGGGGGTT
TTTATAAAGTTTGTATTTTTGAAACTAGCTCTATGTCTATCTAAAAATCAAGTCTCGGCAGTGGCTCATGCCTATAATCCCAGCACTTTG
GGAGGCCGAGGAGGGCAGATCATCTGAGGTCAGGAGTTTGAGACCAGCCTGGCCAGCATGGTGAAACCCCATCTCTACTAAAAATACAAA
AAATTAGCCAGGCGTGGTGGCGCGCACCTGCAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATTGCTTGAACCCGGCAGGAAGAGGT
TGCATTGAGCTGAGATCACGCCATTACACTCCAGCCTGGGCAACAGAGCGAGACTCCGTCTCAAAAAAAAATCATTCAAGTTTCACTGTG
CCTACAGTGAGGAGCTACCTCCTTGTGTCATCAGCTAATAGATCTGAAAGTGATGCCGGTGTCTCTAGGAAAGGAATTGATCATAGCCAA
GTGACTGACATTCTCTCGGTCAGGAAAAGAGCTTGCTTCACAGCCTTTGAAGTATGACTGTATGTGTGGTCCCCTTGTACTTTGGAGACA
GAAGGTACTGGCAGCGAGTGTGGTGGATGGGCAGAAGGTGTAGCATTCGGAGATTATTTCTGTATGTAATTAAGAGACTTTCAAGGGTTA
GCCAGACTTTTTTCCACTCAAGTGTGGATTATCTTTGCTACCTGTGTTAAAGAATATCAGGTTTTGTTTCTTATTGTGATTTTTGAGTCT
AAATGATCCAAGATTTTTAAAATAGATACATAATGAAATCCAGGCCTCTGAAAAATTATGGCAACATTCATTTGGAGTGTGGCTAAAAAC
TCATACTTTATCCAATTTGGTTGCCTCTCTCAGTTACTGCAGTTTATAGAATAATTGAGCTTGAACCATGTGAATGCTCAGAATGTCAAT

>10951_10951_3_C15orf41-LRRC28_C15orf41_chr15_36872162_ENST00000569302_LRRC28_chr15_99926235_ENST00000301981_length(amino acids)=99AA_BP=
MQSQLLGRLRQENCLNPAGRGCIELRSRHYTPAWATERDSVSKKNHSSFTVPTVRSYLLVSSANRSESDAGVSRKGIDHSQVTDILSVRK

--------------------------------------------------------------

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Fusion Gene PPI Analysis for C15orf41-LRRC28


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for C15orf41-LRRC28


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for C15orf41-LRRC28


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneC15orf41C3810185ANEMIA, CONGENITAL DYSERYTHROPOIETIC, TYPE Ib4GENOMICS_ENGLAND;UNIPROT
HgeneC15orf41C0002876Congenital dyserythropoietic anemia2CTD_human;GENOMICS_ENGLAND
HgeneC15orf41C0271933Congenital dyserythropoietic anemia, type I1CTD_human;ORPHANET
TgeneC0023893Liver Cirrhosis, Experimental1CTD_human