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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:CCDC142-M1AP (FusionGDB2 ID:HG84865TG130951)

Fusion Gene Summary for CCDC142-M1AP

check button Fusion gene summary
Fusion gene informationFusion gene name: CCDC142-M1AP
Fusion gene ID: hg84865tg130951
HgeneTgene
Gene symbol

CCDC142

M1AP

Gene ID

84865

130951

Gene namecoiled-coil domain containing 142meiosis 1 associated protein
Synonyms-C2orf65|D6Mm5e|SPATA37
Cytomap('CCDC142')('M1AP')

2p13.1

2p13.1

Type of geneprotein-codingprotein-coding
Descriptioncoiled-coil domain-containing protein 142meiosis 1 arrest proteinmeiosis 1 arresting proteinspermatogenesis associated 37
Modification date2020031320200320
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000290418, ENST00000393965, 
ENST00000471713, 
Fusion gene scores* DoF score4 X 4 X 3=486 X 6 X 5=180
# samples 47
** MAII scorelog2(4/48*10)=-0.263034405833794
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(7/180*10)=-1.36257007938471
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: CCDC142 [Title/Abstract] AND M1AP [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCCDC142(74708350)-M1AP(74808974), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across CCDC142 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across M1AP (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4HNSCTCGA-T3-A92M-01ACCDC142chr2

74708350

-M1APchr2

74808974

-
ChimerDB4HNSCTCGA-T3-A92MCCDC142chr2

74708350

-M1APchr2

74808974

-


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Fusion Gene ORF analysis for CCDC142-M1AP

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000290418ENST00000358434CCDC142chr2

74708350

-M1APchr2

74808974

-
5CDS-5UTRENST00000393965ENST00000358434CCDC142chr2

74708350

-M1APchr2

74808974

-
5CDS-intronENST00000290418ENST00000464686CCDC142chr2

74708350

-M1APchr2

74808974

-
5CDS-intronENST00000393965ENST00000464686CCDC142chr2

74708350

-M1APchr2

74808974

-
5UTR-3CDSENST00000471713ENST00000290536CCDC142chr2

74708350

-M1APchr2

74808974

-
5UTR-3CDSENST00000471713ENST00000409585CCDC142chr2

74708350

-M1APchr2

74808974

-
5UTR-3CDSENST00000471713ENST00000536235CCDC142chr2

74708350

-M1APchr2

74808974

-
5UTR-5UTRENST00000471713ENST00000358434CCDC142chr2

74708350

-M1APchr2

74808974

-
5UTR-intronENST00000471713ENST00000464686CCDC142chr2

74708350

-M1APchr2

74808974

-
In-frameENST00000290418ENST00000290536CCDC142chr2

74708350

-M1APchr2

74808974

-
In-frameENST00000290418ENST00000409585CCDC142chr2

74708350

-M1APchr2

74808974

-
In-frameENST00000290418ENST00000536235CCDC142chr2

74708350

-M1APchr2

74808974

-
In-frameENST00000393965ENST00000290536CCDC142chr2

74708350

-M1APchr2

74808974

-
In-frameENST00000393965ENST00000409585CCDC142chr2

74708350

-M1APchr2

74808974

-
In-frameENST00000393965ENST00000536235CCDC142chr2

74708350

-M1APchr2

74808974

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)
BP loci
(transcript)
Predicted start
(transcript)
Predicted stop
(transcript)
Seq length
(amino acids)
ENST00000393965CCDC142chr274708350-ENST00000290536M1APchr274808974-348616553312652773
ENST00000393965CCDC142chr274708350-ENST00000409585M1APchr274808974-346516553312640769
ENST00000393965CCDC142chr274708350-ENST00000536235M1APchr274808974-301916553312640769
ENST00000290418CCDC142chr274708350-ENST00000290536M1APchr274808974-32481417932414773
ENST00000290418CCDC142chr274708350-ENST00000409585M1APchr274808974-32271417932402769
ENST00000290418CCDC142chr274708350-ENST00000536235M1APchr274808974-27811417932402769

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000393965ENST00000290536CCDC142chr274708350-M1APchr274808974-0.0291014950.9708985
ENST00000393965ENST00000409585CCDC142chr274708350-M1APchr274808974-0.0286726820.9713273
ENST00000393965ENST00000536235CCDC142chr274708350-M1APchr274808974-0.034521840.9654781
ENST00000290418ENST00000290536CCDC142chr274708350-M1APchr274808974-0.0337636430.96623635
ENST00000290418ENST00000409585CCDC142chr274708350-M1APchr274808974-0.0335153040.9664847
ENST00000290418ENST00000536235CCDC142chr274708350-M1APchr274808974-0.042968130.95703185

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Fusion Genomic Features for CCDC142-M1AP


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

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Fusion Protein Features for CCDC142-M1AP


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr2:74708350/chr2:74808974)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCCDC142chr2:74708350chr2:74808974ENST00000290418-3987_110419744.0Coiled coilOntology_term=ECO:0000255
HgeneCCDC142chr2:74708350chr2:74808974ENST00000393965-3987_110419751.0Coiled coilOntology_term=ECO:0000255

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


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Fusion Gene Sequence for CCDC142-M1AP


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>13641_13641_1_CCDC142-M1AP_CCDC142_chr2_74708350_ENST00000290418_M1AP_chr2_74808974_ENST00000290536_length(transcript)=3248nt_BP=1417nt
AAGCCTCCCATTACGGAGCACGAGAGAGTCCATGAAGGTCCCCGCGACTCCCGGACTGGAGAAAACGGCTCTTGCGATGGGGCGAAGTCC
GAGCTGCGGCGGGCGTTGGTCCGTGCAGGGAAGTGGGAATCGTTAGGTTCGTTCTGGACCCGCCGCCCCATGGCCCAGGCGTCTCGCTCA
GGTAGCCTGCCTCCACTCGTTATCGTGCCCCCGCTGAGGGCGCAACCCGGGGGCACTGGGGAGGAGCAGTGGGAGAGAAGTCGAACGGGC
GGTCTTCGCTGGGAGGTTCACTGCTGGCCGAGCGGAACTTCTGGAGGGACGCCGTGGTGGCCGACGCCGGCGGATGTGAGCGAGGACTAC
GAGGCTGATGCTGCGGCCTGGAGGCGGGGGCCCGCAGGTGGCGGCCCGATCCCTCCCGCGCTGCAGCGTCTCCGGGCGGTGTTGCTGCGG
CTGCATCGCGAGCGGGAGCAGCTCCTCCAGGCCCGAGACTGCGCCTACCACCTACAGTCGGCTGTGCGACTCATGAAGACCCTGAGTCCT
GGCTCGCCATCCGGCGGCCCTAGCCCCTTGCCCCAGTGGTGCCGCGACCTGCAGCTGCACCCTTCCCAAGGGGCGGTTCTGCGAATCGGC
CCTGGGGAGACTCTCGAGCCGCTGCTGCTAGCGCGCCCCATCGGACTAGCCGCCCAGTGCCTGGAGGCTGTCATCGAGATGCAGCTTCGC
GCTCTCGGCCGGGAGCCCGCCAGCCCGGGCCTGTCGTCCCAACTCGCCGAGCTGCTCTTTGCACTTCCCGCCTACCACACACTACAGAGA
AAAGCCTTGAGCCACGTCCCAGGGGCCGCACGTCCTTTCCCCACGTCCCGTGTGCTCCGCCTCTTGACGGGGGAGCGGGGTTGCCAGGTG
GCAAGTCGGCTGGACGAGGCGCTCCAAGGATCGGCGTTGAGGGACCAGCTCCGCAGGCGGTGCCAAGAGGAGGGGGATCTGCTACCAGGG
CTGCTGGGCCTGGTCGGGGGCGTGGCGGGTTCAGCCAGCTGTGGACTAGGGCTCGGAGGGGCTGGGGCCTTGTGGAGCCAATACTGGACC
CTGCTGTGGGCAGCCTGTGCTCAGAGTCTGGACCTAAATCTGGGACCCTGGAGGGACCCCAGGGCAACAGCGCAACAGCTGAGTCAGGCA
CTGGGTCAGGCATCCCTGCCTCAGGAGTGTGAGAAGGAGCTGGCATCTTTGTGTCACAGACTACTTCATCAGTCGCTTATCTGGAGCTGG
GACCAAGGTTTCTGCCAGGCCTTGGGATCAGCTCTTGGGGGTCAGAGCAGCCTTCCCACATCCTCTGGCACTGCTGAACTTTTGCAGCAG
CTCTTTCCTCCTCTCTTGGATGCCCTTCGAGAGCCCAGGTTACGACGGATTTTCTGCCAGCCTGCAGAGAGTTCTATTCTGGGAACTGAC
ATTGACCTTCAGACTATAGACAATGATATCGTCAGCATGGAGATTTTCTTCAAAGCCTGGCTACATAACAGTGGAACAGACCAAGAACAA
ATCCATCTTCTTCTTTCTTCACAGTGTTTCAGCAACATTTCCAGACCCAGAGATAATCCAATGTGTCTGAAATGTGATCTCCAAGAGCGA
CTGCTCTGCCCATCCCTACTCGCTGGCACAGCTGACGGCTCCTTGAGAATGGATGACCCTAAAGGAGACTTCATCACACTCTACCAGATG
GCTTCCCAGTCATCGGCCTCTCATTACAAGCTCCAAGTGATCAAGGCTTTAAAATCTAGCGGGCTCTGCGAGTCATTGACATATGGACTC
CCGTTCATCCTCAGACCTACAAGCTGTTGGCAGCTGGACTGGGATGAGCTGGAGACAAATCAGCAACATTTCCATGCTTTGTGTCACAGC
CTGCTGAAAAGGGAATGGCTGCTGTTAGCCAAGGGGGAACCACCGGGCCCAGGACACAGCCAGAGAATTCCTGCCAGCACCTTCTATGTG
ATCATGCCGTCACACTCCCTCACACTGCTGGTAAAGGCGGTGGCCACGCGGGAACTGATGCTGCCCAGCACCTTCCCCCTGCTACCTGAG
GACCCACATGATGATAGCCTTAAGAATGTGGAGAGCATGCTGGACAGCCTGGAGCTGGAGCCCACCTACAACCCCTTGCATGTTCAAAGC
CACCTGTACTCACACCTGAGCAGCATCTATGCCAAGCCTCAGGGGCGGCTCCACCCACACTGGGAGAGCCGAGCTCCGAGAAAGCATCCC
TGCAAGACTGGGCAGTTGCAGACCAACCGAGCTCGAGCTACTGTGGCCCCCCTGCCTATGACTCCTGTCCCAGGCAGAGCCTCCAAGATG
CCAGCAGCCAGCAAATCTTCCTCAGATGCCTTCTTCCTGCCTTCAGAGTGGGAGAAGGATCCCTCAAGGCCCTAAGTCACCAGCACCAGA
GCCCAGCTGCCCAGCTTAACCATATCCATGCTCAGGTTCACATAATGGCTATCTGTGGTCAGACTTGCTCTCTATCCGCCTGAGCCTCTG
TGAGTGAGGGCTGACTGGGAAACAACAGCCTTCCTGTCCTGTTTCAGTGCTGTCCCACTCCTCAAGTCTGGAAGCGACACACCCGAGCCT
GTCCTTTCTCCAGCAAGGACTTTCATTTTCTTTAGAATCATTTGCTACTGTTTACACAGGTGAAGATTAAACACCCAGTAAGCTTCTACC
ATTGTTAGGAGCATTCATAACTCAGAATTTCTTCTTGTAGCTCTGTGTAAGCAGGTGGATGAGGTCAGATCACCTTTGGTAAACTGGACC
TCAGGAACAAGGATGAGGTTTTGAAAGCTCATAAAAGACAAGTAAGATTGAAATCCAAGCCTCATTTCAGAGCCTGTGCCCTTCCCACTA
CACCACCAGGCTTCAGCCTCCAAAGAGACAAGTGCTTGGTACCTACATGCAAAGTGTGTGTGCTGGGGGGTGGGAGGGCTGCCCAGAACA
GGGGAGAGGATGGTGTAAAAAAAGACCTACTCCTTTCCTGTTACCCTCTCCCCACATGTACCAACCTTCCTGTTGCTCCCTCCATCCACA
GAATAATAGCTACCATTTATAAAATGTTTACTCTGGGCTGGGAGCAGTGGCTCACACCTGTAATCCCAACACTTTGAGAGGCTGAGGTGG
GATGATCACTTGAGGCCAGGAGTTCGAGACCAGCCTGAGCAACACTGTGAGACCCCCCCGCCATCTCTACATAAATAATAAAAACTTTTA

>13641_13641_1_CCDC142-M1AP_CCDC142_chr2_74708350_ENST00000290418_M1AP_chr2_74808974_ENST00000290536_length(amino acids)=773AA_BP=440
MRRALVRAGKWESLGSFWTRRPMAQASRSGSLPPLVIVPPLRAQPGGTGEEQWERSRTGGLRWEVHCWPSGTSGGTPWWPTPADVSEDYE
ADAAAWRRGPAGGGPIPPALQRLRAVLLRLHREREQLLQARDCAYHLQSAVRLMKTLSPGSPSGGPSPLPQWCRDLQLHPSQGAVLRIGP
GETLEPLLLARPIGLAAQCLEAVIEMQLRALGREPASPGLSSQLAELLFALPAYHTLQRKALSHVPGAARPFPTSRVLRLLTGERGCQVA
SRLDEALQGSALRDQLRRRCQEEGDLLPGLLGLVGGVAGSASCGLGLGGAGALWSQYWTLLWAACAQSLDLNLGPWRDPRATAQQLSQAL
GQASLPQECEKELASLCHRLLHQSLIWSWDQGFCQALGSALGGQSSLPTSSGTAELLQQLFPPLLDALREPRLRRIFCQPAESSILGTDI
DLQTIDNDIVSMEIFFKAWLHNSGTDQEQIHLLLSSQCFSNISRPRDNPMCLKCDLQERLLCPSLLAGTADGSLRMDDPKGDFITLYQMA
SQSSASHYKLQVIKALKSSGLCESLTYGLPFILRPTSCWQLDWDELETNQQHFHALCHSLLKREWLLLAKGEPPGPGHSQRIPASTFYVI
MPSHSLTLLVKAVATRELMLPSTFPLLPEDPHDDSLKNVESMLDSLELEPTYNPLHVQSHLYSHLSSIYAKPQGRLHPHWESRAPRKHPC

--------------------------------------------------------------
>13641_13641_2_CCDC142-M1AP_CCDC142_chr2_74708350_ENST00000290418_M1AP_chr2_74808974_ENST00000409585_length(transcript)=3227nt_BP=1417nt
AAGCCTCCCATTACGGAGCACGAGAGAGTCCATGAAGGTCCCCGCGACTCCCGGACTGGAGAAAACGGCTCTTGCGATGGGGCGAAGTCC
GAGCTGCGGCGGGCGTTGGTCCGTGCAGGGAAGTGGGAATCGTTAGGTTCGTTCTGGACCCGCCGCCCCATGGCCCAGGCGTCTCGCTCA
GGTAGCCTGCCTCCACTCGTTATCGTGCCCCCGCTGAGGGCGCAACCCGGGGGCACTGGGGAGGAGCAGTGGGAGAGAAGTCGAACGGGC
GGTCTTCGCTGGGAGGTTCACTGCTGGCCGAGCGGAACTTCTGGAGGGACGCCGTGGTGGCCGACGCCGGCGGATGTGAGCGAGGACTAC
GAGGCTGATGCTGCGGCCTGGAGGCGGGGGCCCGCAGGTGGCGGCCCGATCCCTCCCGCGCTGCAGCGTCTCCGGGCGGTGTTGCTGCGG
CTGCATCGCGAGCGGGAGCAGCTCCTCCAGGCCCGAGACTGCGCCTACCACCTACAGTCGGCTGTGCGACTCATGAAGACCCTGAGTCCT
GGCTCGCCATCCGGCGGCCCTAGCCCCTTGCCCCAGTGGTGCCGCGACCTGCAGCTGCACCCTTCCCAAGGGGCGGTTCTGCGAATCGGC
CCTGGGGAGACTCTCGAGCCGCTGCTGCTAGCGCGCCCCATCGGACTAGCCGCCCAGTGCCTGGAGGCTGTCATCGAGATGCAGCTTCGC
GCTCTCGGCCGGGAGCCCGCCAGCCCGGGCCTGTCGTCCCAACTCGCCGAGCTGCTCTTTGCACTTCCCGCCTACCACACACTACAGAGA
AAAGCCTTGAGCCACGTCCCAGGGGCCGCACGTCCTTTCCCCACGTCCCGTGTGCTCCGCCTCTTGACGGGGGAGCGGGGTTGCCAGGTG
GCAAGTCGGCTGGACGAGGCGCTCCAAGGATCGGCGTTGAGGGACCAGCTCCGCAGGCGGTGCCAAGAGGAGGGGGATCTGCTACCAGGG
CTGCTGGGCCTGGTCGGGGGCGTGGCGGGTTCAGCCAGCTGTGGACTAGGGCTCGGAGGGGCTGGGGCCTTGTGGAGCCAATACTGGACC
CTGCTGTGGGCAGCCTGTGCTCAGAGTCTGGACCTAAATCTGGGACCCTGGAGGGACCCCAGGGCAACAGCGCAACAGCTGAGTCAGGCA
CTGGGTCAGGCATCCCTGCCTCAGGAGTGTGAGAAGGAGCTGGCATCTTTGTGTCACAGACTACTTCATCAGTCGCTTATCTGGAGCTGG
GACCAAGGTTTCTGCCAGGCCTTGGGATCAGCTCTTGGGGGTCAGAGCAGCCTTCCCACATCCTCTGGCACTGCTGAACTTTTGCAGCAG
CTCTTTCCTCCTCTCTTGGATGCCCTTCGAGAGCCCAGGTTACGACGGATTTTCTGCCAGCCTGCAGAGAGTTCTATTCTGGGAACTGAC
ATTGACCTTCAGACTATAGACAATGATATCGTCAGCATGGAGATTTTCTTCAAAGCCTGGCTACATAACAGTGGAACAGACCAAGAACAA
ATCCATCTTCTTCTTTCTTCACAGTGTTTCAGCAACATTTCCAGACCCAGAGATAATCCAATGTGTCTGAAATGTGATCTCCAAGAGCGA
CTGCTCTGCCCATCCCTACTCGCTGGCACAGCTGACGGCTCCTTGAGAATGGATGACCCTAAAGGAGACTTCATCACACTCTACCAGATG
GCTTCCCAGTCATCGGCCTCTCATTACAAGCTCCAAGTGATCAAGGCTTTAAAATCTAGCGGGCTCTGCGAGTCATTGACATATGGACTC
CCGTTCATCCTCAGACCTACAAGCTGTTGGCAGCTGGACTGGGATGAGCTGGAGACAAATCAGCAACATTTCCATGCTTTGTGTCACAGC
CTGCTGAAAAGGGAATGGCTGCTGTTAGCCAAGGGGGAACCACCGGGCCCAGGACACAGCCAGAGAATTCCTGCCAGCACCTTCTATGTG
ATCATGCCGTCACACTCCCTCACACTGCTGGTAAAGGCGGTGGCCACGCGGGAACTGATGCTGCCCAGCACCTTCCCCCTGCTACCTGAG
GACCCACATGATGATAGCCTTAAGAATGTGGAGAGCATGCTGGACAGCCTGGAGCTGGAGCCCACCTACAACCCCTTGCATGTTCAAAGC
CACCTGTACTCACACCTGAGCAGCATCTATGCCAAGCCTCAGGGGCGGCTCCACCCACACTGGGAGAGCCGAGCTCCGAGAAAGACTGGG
CAGTTGCAGACCAACCGAGCTCGAGCTACTGTGGCCCCCCTGCCTATGACTCCTGTCCCAGGCAGAGCCTCCAAGATGCCAGCAGCCAGC
AAATCTTCCTCAGATGCCTTCTTCCTGCCTTCAGAGTGGGAGAAGGATCCCTCAAGGCCCTAAGTCACCAGCACCAGAGCCCAGCTGCCC
AGCTTAACCATATCCATGCTCAGGTTCACATAATGGCTATCTGTGGTCAGACTTGCTCTCTATCCGCCTGAGCCTCTGTGAGTGAGGGCT
GACTGGGAAACAACAGCCTTCCTGTCCTGTTTCAGTGCTGTCCCACTCCTCAAGTCTGGAAGCGACACACCCGAGCCTGTCCTTTCTCCA
GCAAGGACTTTCATTTTCTTTAGAATCATTTGCTACTGTTTACACAGGTGAAGATTAAACACCCAGTAAGCTTCTACCATTGTTAGGAGC
ATTCATAACTCAGAATTTCTTCTTGTAGCTCTGTGTAAGCAGGTGGATGAGGTCAGATCACCTTTGGTAAACTGGACCTCAGGAACAAGG
ATGAGGTTTTGAAAGCTCATAAAAGACAAGTAAGATTGAAATCCAAGCCTCATTTCAGAGCCTGTGCCCTTCCCACTACACCACCAGGCT
TCAGCCTCCAAAGAGACAAGTGCTTGGTACCTACATGCAAAGTGTGTGTGCTGGGGGGTGGGAGGGCTGCCCAGAACAGGGGAGAGGATG
GTGTAAAAAAAGACCTACTCCTTTCCTGTTACCCTCTCCCCACATGTACCAACCTTCCTGTTGCTCCCTCCATCCACAGAATAATAGCTA
CCATTTATAAAATGTTTACTCTGGGCTGGGAGCAGTGGCTCACACCTGTAATCCCAACACTTTGAGAGGCTGAGGTGGGATGATCACTTG

>13641_13641_2_CCDC142-M1AP_CCDC142_chr2_74708350_ENST00000290418_M1AP_chr2_74808974_ENST00000409585_length(amino acids)=769AA_BP=440
MRRALVRAGKWESLGSFWTRRPMAQASRSGSLPPLVIVPPLRAQPGGTGEEQWERSRTGGLRWEVHCWPSGTSGGTPWWPTPADVSEDYE
ADAAAWRRGPAGGGPIPPALQRLRAVLLRLHREREQLLQARDCAYHLQSAVRLMKTLSPGSPSGGPSPLPQWCRDLQLHPSQGAVLRIGP
GETLEPLLLARPIGLAAQCLEAVIEMQLRALGREPASPGLSSQLAELLFALPAYHTLQRKALSHVPGAARPFPTSRVLRLLTGERGCQVA
SRLDEALQGSALRDQLRRRCQEEGDLLPGLLGLVGGVAGSASCGLGLGGAGALWSQYWTLLWAACAQSLDLNLGPWRDPRATAQQLSQAL
GQASLPQECEKELASLCHRLLHQSLIWSWDQGFCQALGSALGGQSSLPTSSGTAELLQQLFPPLLDALREPRLRRIFCQPAESSILGTDI
DLQTIDNDIVSMEIFFKAWLHNSGTDQEQIHLLLSSQCFSNISRPRDNPMCLKCDLQERLLCPSLLAGTADGSLRMDDPKGDFITLYQMA
SQSSASHYKLQVIKALKSSGLCESLTYGLPFILRPTSCWQLDWDELETNQQHFHALCHSLLKREWLLLAKGEPPGPGHSQRIPASTFYVI
MPSHSLTLLVKAVATRELMLPSTFPLLPEDPHDDSLKNVESMLDSLELEPTYNPLHVQSHLYSHLSSIYAKPQGRLHPHWESRAPRKTGQ

--------------------------------------------------------------
>13641_13641_3_CCDC142-M1AP_CCDC142_chr2_74708350_ENST00000290418_M1AP_chr2_74808974_ENST00000536235_length(transcript)=2781nt_BP=1417nt
AAGCCTCCCATTACGGAGCACGAGAGAGTCCATGAAGGTCCCCGCGACTCCCGGACTGGAGAAAACGGCTCTTGCGATGGGGCGAAGTCC
GAGCTGCGGCGGGCGTTGGTCCGTGCAGGGAAGTGGGAATCGTTAGGTTCGTTCTGGACCCGCCGCCCCATGGCCCAGGCGTCTCGCTCA
GGTAGCCTGCCTCCACTCGTTATCGTGCCCCCGCTGAGGGCGCAACCCGGGGGCACTGGGGAGGAGCAGTGGGAGAGAAGTCGAACGGGC
GGTCTTCGCTGGGAGGTTCACTGCTGGCCGAGCGGAACTTCTGGAGGGACGCCGTGGTGGCCGACGCCGGCGGATGTGAGCGAGGACTAC
GAGGCTGATGCTGCGGCCTGGAGGCGGGGGCCCGCAGGTGGCGGCCCGATCCCTCCCGCGCTGCAGCGTCTCCGGGCGGTGTTGCTGCGG
CTGCATCGCGAGCGGGAGCAGCTCCTCCAGGCCCGAGACTGCGCCTACCACCTACAGTCGGCTGTGCGACTCATGAAGACCCTGAGTCCT
GGCTCGCCATCCGGCGGCCCTAGCCCCTTGCCCCAGTGGTGCCGCGACCTGCAGCTGCACCCTTCCCAAGGGGCGGTTCTGCGAATCGGC
CCTGGGGAGACTCTCGAGCCGCTGCTGCTAGCGCGCCCCATCGGACTAGCCGCCCAGTGCCTGGAGGCTGTCATCGAGATGCAGCTTCGC
GCTCTCGGCCGGGAGCCCGCCAGCCCGGGCCTGTCGTCCCAACTCGCCGAGCTGCTCTTTGCACTTCCCGCCTACCACACACTACAGAGA
AAAGCCTTGAGCCACGTCCCAGGGGCCGCACGTCCTTTCCCCACGTCCCGTGTGCTCCGCCTCTTGACGGGGGAGCGGGGTTGCCAGGTG
GCAAGTCGGCTGGACGAGGCGCTCCAAGGATCGGCGTTGAGGGACCAGCTCCGCAGGCGGTGCCAAGAGGAGGGGGATCTGCTACCAGGG
CTGCTGGGCCTGGTCGGGGGCGTGGCGGGTTCAGCCAGCTGTGGACTAGGGCTCGGAGGGGCTGGGGCCTTGTGGAGCCAATACTGGACC
CTGCTGTGGGCAGCCTGTGCTCAGAGTCTGGACCTAAATCTGGGACCCTGGAGGGACCCCAGGGCAACAGCGCAACAGCTGAGTCAGGCA
CTGGGTCAGGCATCCCTGCCTCAGGAGTGTGAGAAGGAGCTGGCATCTTTGTGTCACAGACTACTTCATCAGTCGCTTATCTGGAGCTGG
GACCAAGGTTTCTGCCAGGCCTTGGGATCAGCTCTTGGGGGTCAGAGCAGCCTTCCCACATCCTCTGGCACTGCTGAACTTTTGCAGCAG
CTCTTTCCTCCTCTCTTGGATGCCCTTCGAGAGCCCAGGTTACGACGGATTTTCTGCCAGCCTGCAGAGAGTTCTATTCTGGGAACTGAC
ATTGACCTTCAGACTATAGACAATGATATCGTCAGCATGGAGATTTTCTTCAAAGCCTGGCTACATAACAGTGGAACAGACCAAGAACAA
ATCCATCTTCTTCTTTCTTCACAGTGTTTCAGCAACATTTCCAGACCCAGAGATAATCCAATGTGTCTGAAATGTGATCTCCAAGAGCGA
CTGCTCTGCCCATCCCTACTCGCTGGCACAGCTGACGGCTCCTTGAGAATGGATGACCCTAAAGGAGACTTCATCACACTCTACCAGATG
GCTTCCCAGTCATCGGCCTCTCATTACAAGCTCCAAGTGATCAAGGCTTTAAAATCTAGCGGGCTCTGCGAGTCATTGACATATGGACTC
CCGTTCATCCTCAGACCTACAAGCTGTTGGCAGCTGGACTGGGATGAGCTGGAGACAAATCAGCAACATTTCCATGCTTTGTGTCACAGC
CTGCTGAAAAGGGAATGGCTGCTGTTAGCCAAGGGGGAACCACCGGGCCCAGGACACAGCCAGAGAATTCCTGCCAGCACCTTCTATGTG
ATCATGCCGTCACACTCCCTCACACTGCTGGTAAAGGCGGTGGCCACGCGGGAACTGATGCTGCCCAGCACCTTCCCCCTGCTACCTGAG
GACCCACATGATGATAGCCTTAAGAATGTGGAGAGCATGCTGGACAGCCTGGAGCTGGAGCCCACCTACAACCCCTTGCATGTTCAAAGC
CACCTGTACTCACACCTGAGCAGCATCTATGCCAAGCCTCAGGGGCGGCTCCACCCACACTGGGAGAGCCGAGCTCCGAGAAAGACTGGG
CAGTTGCAGACCAACCGAGCTCGAGCTACTGTGGCCCCCCTGCCTATGACTCCTGTCCCAGGCAGAGCCTCCAAGATGCCAGCAGCCAGC
AAATCTTCCTCAGATGCCTTCTTCCTGCCTTCAGAGTGGGAGAAGGATCCCTCAAGGCCCTAAGTCACCAGCACCAGAGCCCAGCTGCCC
AGCTTAACCATATCCATGCTCAGGTTCACATAATGGCTATCTGTGGTCAGACTTGCTCTCTATCCGCCTGAGCCTCTGTGAGTGAGGGCT
GACTGGGAAACAACAGCCTTCCTGTCCTGTTTCAGTGCTGTCCCACTCCTCAAGTCTGGAAGCGACACACCCGAGCCTGTCCTTTCTCCA
GCAAGGACTTTCATTTTCTTTAGAATCATTTGCTACTGTTTACACAGGTGAAGATTAAACACCCAGTAAGCTTCTACCATTGTTAGGAGC

>13641_13641_3_CCDC142-M1AP_CCDC142_chr2_74708350_ENST00000290418_M1AP_chr2_74808974_ENST00000536235_length(amino acids)=769AA_BP=440
MRRALVRAGKWESLGSFWTRRPMAQASRSGSLPPLVIVPPLRAQPGGTGEEQWERSRTGGLRWEVHCWPSGTSGGTPWWPTPADVSEDYE
ADAAAWRRGPAGGGPIPPALQRLRAVLLRLHREREQLLQARDCAYHLQSAVRLMKTLSPGSPSGGPSPLPQWCRDLQLHPSQGAVLRIGP
GETLEPLLLARPIGLAAQCLEAVIEMQLRALGREPASPGLSSQLAELLFALPAYHTLQRKALSHVPGAARPFPTSRVLRLLTGERGCQVA
SRLDEALQGSALRDQLRRRCQEEGDLLPGLLGLVGGVAGSASCGLGLGGAGALWSQYWTLLWAACAQSLDLNLGPWRDPRATAQQLSQAL
GQASLPQECEKELASLCHRLLHQSLIWSWDQGFCQALGSALGGQSSLPTSSGTAELLQQLFPPLLDALREPRLRRIFCQPAESSILGTDI
DLQTIDNDIVSMEIFFKAWLHNSGTDQEQIHLLLSSQCFSNISRPRDNPMCLKCDLQERLLCPSLLAGTADGSLRMDDPKGDFITLYQMA
SQSSASHYKLQVIKALKSSGLCESLTYGLPFILRPTSCWQLDWDELETNQQHFHALCHSLLKREWLLLAKGEPPGPGHSQRIPASTFYVI
MPSHSLTLLVKAVATRELMLPSTFPLLPEDPHDDSLKNVESMLDSLELEPTYNPLHVQSHLYSHLSSIYAKPQGRLHPHWESRAPRKTGQ

--------------------------------------------------------------
>13641_13641_4_CCDC142-M1AP_CCDC142_chr2_74708350_ENST00000393965_M1AP_chr2_74808974_ENST00000290536_length(transcript)=3486nt_BP=1655nt
CTGCATAAAATCCTACTCGAAACGTTCAGACCACAGGTGGACCCAAGAGGGGCTGCCTCTGCCCTCCTAGACCCCCACTGGTCTTGTCAT
ACCGCTCACCTAGCTTGATCCGCCCCACAGTCTTTGGAATCGGCGCCATCGCATCTACAGTGACCCGGAAATGAAAGGTAGTCTAGTATT
TGATACCAGCCAAAGGGCGGGGTGGGACAGAGTGGGCGGCCATGTTTGTTAGGGGCAGAAGCCTCCCATTACGGAGCACGAGAGAGTCCA
TGAAGGTCCCCGCGACTCCCGGACTGGAGAAAACGGCTCTTGCGATGGGGCGAAGTCCGAGCTGCGGCGGGCGTTGGTCCGTGCAGGGAA
GTGGGAATCGTTAGGTTCGTTCTGGACCCGCCGCCCCATGGCCCAGGCGTCTCGCTCAGGTAGCCTGCCTCCACTCGTTATCGTGCCCCC
GCTGAGGGCGCAACCCGGGGGCACTGGGGAGGAGCAGTGGGAGAGAAGTCGAACGGGCGGTCTTCGCTGGGAGGTTCACTGCTGGCCGAG
CGGAACTTCTGGAGGGACGCCGTGGTGGCCGACGCCGGCGGATGTGAGCGAGGACTACGAGGCTGATGCTGCGGCCTGGAGGCGGGGGCC
CGCAGGTGGCGGCCCGATCCCTCCCGCGCTGCAGCGTCTCCGGGCGGTGTTGCTGCGGCTGCATCGCGAGCGGGAGCAGCTCCTCCAGGC
CCGAGACTGCGCCTACCACCTACAGTCGGCTGTGCGACTCATGAAGACCCTGAGTCCTGGCTCGCCATCCGGCGGCCCTAGCCCCTTGCC
CCAGTGGTGCCGCGACCTGCAGCTGCACCCTTCCCAAGGGGCGGTTCTGCGAATCGGCCCTGGGGAGACTCTCGAGCCGCTGCTGCTAGC
GCGCCCCATCGGACTAGCCGCCCAGTGCCTGGAGGCTGTCATCGAGATGCAGCTTCGCGCTCTCGGCCGGGAGCCCGCCAGCCCGGGCCT
GTCGTCCCAACTCGCCGAGCTGCTCTTTGCACTTCCCGCCTACCACACACTACAGAGAAAAGCCTTGAGCCACGTCCCAGGGGCCGCACG
TCCTTTCCCCACGTCCCGTGTGCTCCGCCTCTTGACGGGGGAGCGGGGTTGCCAGGTGGCAAGTCGGCTGGACGAGGCGCTCCAAGGATC
GGCGTTGAGGGACCAGCTCCGCAGGCGGTGCCAAGAGGAGGGGGATCTGCTACCAGGGCTGCTGGGCCTGGTCGGGGGCGTGGCGGGTTC
AGCCAGCTGTGGACTAGGGCTCGGAGGGGCTGGGGCCTTGTGGAGCCAATACTGGACCCTGCTGTGGGCAGCCTGTGCTCAGAGTCTGGA
CCTAAATCTGGGACCCTGGAGGGACCCCAGGGCAACAGCGCAACAGCTGAGTCAGGCACTGGGTCAGGCATCCCTGCCTCAGGAGTGTGA
GAAGGAGCTGGCATCTTTGTGTCACAGACTACTTCATCAGTCGCTTATCTGGAGCTGGGACCAAGGTTTCTGCCAGGCCTTGGGATCAGC
TCTTGGGGGTCAGAGCAGCCTTCCCACATCCTCTGGCACTGCTGAACTTTTGCAGCAGCTCTTTCCTCCTCTCTTGGATGCCCTTCGAGA
GCCCAGGTTACGACGGATTTTCTGCCAGCCTGCAGAGAGTTCTATTCTGGGAACTGACATTGACCTTCAGACTATAGACAATGATATCGT
CAGCATGGAGATTTTCTTCAAAGCCTGGCTACATAACAGTGGAACAGACCAAGAACAAATCCATCTTCTTCTTTCTTCACAGTGTTTCAG
CAACATTTCCAGACCCAGAGATAATCCAATGTGTCTGAAATGTGATCTCCAAGAGCGACTGCTCTGCCCATCCCTACTCGCTGGCACAGC
TGACGGCTCCTTGAGAATGGATGACCCTAAAGGAGACTTCATCACACTCTACCAGATGGCTTCCCAGTCATCGGCCTCTCATTACAAGCT
CCAAGTGATCAAGGCTTTAAAATCTAGCGGGCTCTGCGAGTCATTGACATATGGACTCCCGTTCATCCTCAGACCTACAAGCTGTTGGCA
GCTGGACTGGGATGAGCTGGAGACAAATCAGCAACATTTCCATGCTTTGTGTCACAGCCTGCTGAAAAGGGAATGGCTGCTGTTAGCCAA
GGGGGAACCACCGGGCCCAGGACACAGCCAGAGAATTCCTGCCAGCACCTTCTATGTGATCATGCCGTCACACTCCCTCACACTGCTGGT
AAAGGCGGTGGCCACGCGGGAACTGATGCTGCCCAGCACCTTCCCCCTGCTACCTGAGGACCCACATGATGATAGCCTTAAGAATGTGGA
GAGCATGCTGGACAGCCTGGAGCTGGAGCCCACCTACAACCCCTTGCATGTTCAAAGCCACCTGTACTCACACCTGAGCAGCATCTATGC
CAAGCCTCAGGGGCGGCTCCACCCACACTGGGAGAGCCGAGCTCCGAGAAAGCATCCCTGCAAGACTGGGCAGTTGCAGACCAACCGAGC
TCGAGCTACTGTGGCCCCCCTGCCTATGACTCCTGTCCCAGGCAGAGCCTCCAAGATGCCAGCAGCCAGCAAATCTTCCTCAGATGCCTT
CTTCCTGCCTTCAGAGTGGGAGAAGGATCCCTCAAGGCCCTAAGTCACCAGCACCAGAGCCCAGCTGCCCAGCTTAACCATATCCATGCT
CAGGTTCACATAATGGCTATCTGTGGTCAGACTTGCTCTCTATCCGCCTGAGCCTCTGTGAGTGAGGGCTGACTGGGAAACAACAGCCTT
CCTGTCCTGTTTCAGTGCTGTCCCACTCCTCAAGTCTGGAAGCGACACACCCGAGCCTGTCCTTTCTCCAGCAAGGACTTTCATTTTCTT
TAGAATCATTTGCTACTGTTTACACAGGTGAAGATTAAACACCCAGTAAGCTTCTACCATTGTTAGGAGCATTCATAACTCAGAATTTCT
TCTTGTAGCTCTGTGTAAGCAGGTGGATGAGGTCAGATCACCTTTGGTAAACTGGACCTCAGGAACAAGGATGAGGTTTTGAAAGCTCAT
AAAAGACAAGTAAGATTGAAATCCAAGCCTCATTTCAGAGCCTGTGCCCTTCCCACTACACCACCAGGCTTCAGCCTCCAAAGAGACAAG
TGCTTGGTACCTACATGCAAAGTGTGTGTGCTGGGGGGTGGGAGGGCTGCCCAGAACAGGGGAGAGGATGGTGTAAAAAAAGACCTACTC
CTTTCCTGTTACCCTCTCCCCACATGTACCAACCTTCCTGTTGCTCCCTCCATCCACAGAATAATAGCTACCATTTATAAAATGTTTACT
CTGGGCTGGGAGCAGTGGCTCACACCTGTAATCCCAACACTTTGAGAGGCTGAGGTGGGATGATCACTTGAGGCCAGGAGTTCGAGACCA

>13641_13641_4_CCDC142-M1AP_CCDC142_chr2_74708350_ENST00000393965_M1AP_chr2_74808974_ENST00000290536_length(amino acids)=773AA_BP=440
MRRALVRAGKWESLGSFWTRRPMAQASRSGSLPPLVIVPPLRAQPGGTGEEQWERSRTGGLRWEVHCWPSGTSGGTPWWPTPADVSEDYE
ADAAAWRRGPAGGGPIPPALQRLRAVLLRLHREREQLLQARDCAYHLQSAVRLMKTLSPGSPSGGPSPLPQWCRDLQLHPSQGAVLRIGP
GETLEPLLLARPIGLAAQCLEAVIEMQLRALGREPASPGLSSQLAELLFALPAYHTLQRKALSHVPGAARPFPTSRVLRLLTGERGCQVA
SRLDEALQGSALRDQLRRRCQEEGDLLPGLLGLVGGVAGSASCGLGLGGAGALWSQYWTLLWAACAQSLDLNLGPWRDPRATAQQLSQAL
GQASLPQECEKELASLCHRLLHQSLIWSWDQGFCQALGSALGGQSSLPTSSGTAELLQQLFPPLLDALREPRLRRIFCQPAESSILGTDI
DLQTIDNDIVSMEIFFKAWLHNSGTDQEQIHLLLSSQCFSNISRPRDNPMCLKCDLQERLLCPSLLAGTADGSLRMDDPKGDFITLYQMA
SQSSASHYKLQVIKALKSSGLCESLTYGLPFILRPTSCWQLDWDELETNQQHFHALCHSLLKREWLLLAKGEPPGPGHSQRIPASTFYVI
MPSHSLTLLVKAVATRELMLPSTFPLLPEDPHDDSLKNVESMLDSLELEPTYNPLHVQSHLYSHLSSIYAKPQGRLHPHWESRAPRKHPC

--------------------------------------------------------------
>13641_13641_5_CCDC142-M1AP_CCDC142_chr2_74708350_ENST00000393965_M1AP_chr2_74808974_ENST00000409585_length(transcript)=3465nt_BP=1655nt
CTGCATAAAATCCTACTCGAAACGTTCAGACCACAGGTGGACCCAAGAGGGGCTGCCTCTGCCCTCCTAGACCCCCACTGGTCTTGTCAT
ACCGCTCACCTAGCTTGATCCGCCCCACAGTCTTTGGAATCGGCGCCATCGCATCTACAGTGACCCGGAAATGAAAGGTAGTCTAGTATT
TGATACCAGCCAAAGGGCGGGGTGGGACAGAGTGGGCGGCCATGTTTGTTAGGGGCAGAAGCCTCCCATTACGGAGCACGAGAGAGTCCA
TGAAGGTCCCCGCGACTCCCGGACTGGAGAAAACGGCTCTTGCGATGGGGCGAAGTCCGAGCTGCGGCGGGCGTTGGTCCGTGCAGGGAA
GTGGGAATCGTTAGGTTCGTTCTGGACCCGCCGCCCCATGGCCCAGGCGTCTCGCTCAGGTAGCCTGCCTCCACTCGTTATCGTGCCCCC
GCTGAGGGCGCAACCCGGGGGCACTGGGGAGGAGCAGTGGGAGAGAAGTCGAACGGGCGGTCTTCGCTGGGAGGTTCACTGCTGGCCGAG
CGGAACTTCTGGAGGGACGCCGTGGTGGCCGACGCCGGCGGATGTGAGCGAGGACTACGAGGCTGATGCTGCGGCCTGGAGGCGGGGGCC
CGCAGGTGGCGGCCCGATCCCTCCCGCGCTGCAGCGTCTCCGGGCGGTGTTGCTGCGGCTGCATCGCGAGCGGGAGCAGCTCCTCCAGGC
CCGAGACTGCGCCTACCACCTACAGTCGGCTGTGCGACTCATGAAGACCCTGAGTCCTGGCTCGCCATCCGGCGGCCCTAGCCCCTTGCC
CCAGTGGTGCCGCGACCTGCAGCTGCACCCTTCCCAAGGGGCGGTTCTGCGAATCGGCCCTGGGGAGACTCTCGAGCCGCTGCTGCTAGC
GCGCCCCATCGGACTAGCCGCCCAGTGCCTGGAGGCTGTCATCGAGATGCAGCTTCGCGCTCTCGGCCGGGAGCCCGCCAGCCCGGGCCT
GTCGTCCCAACTCGCCGAGCTGCTCTTTGCACTTCCCGCCTACCACACACTACAGAGAAAAGCCTTGAGCCACGTCCCAGGGGCCGCACG
TCCTTTCCCCACGTCCCGTGTGCTCCGCCTCTTGACGGGGGAGCGGGGTTGCCAGGTGGCAAGTCGGCTGGACGAGGCGCTCCAAGGATC
GGCGTTGAGGGACCAGCTCCGCAGGCGGTGCCAAGAGGAGGGGGATCTGCTACCAGGGCTGCTGGGCCTGGTCGGGGGCGTGGCGGGTTC
AGCCAGCTGTGGACTAGGGCTCGGAGGGGCTGGGGCCTTGTGGAGCCAATACTGGACCCTGCTGTGGGCAGCCTGTGCTCAGAGTCTGGA
CCTAAATCTGGGACCCTGGAGGGACCCCAGGGCAACAGCGCAACAGCTGAGTCAGGCACTGGGTCAGGCATCCCTGCCTCAGGAGTGTGA
GAAGGAGCTGGCATCTTTGTGTCACAGACTACTTCATCAGTCGCTTATCTGGAGCTGGGACCAAGGTTTCTGCCAGGCCTTGGGATCAGC
TCTTGGGGGTCAGAGCAGCCTTCCCACATCCTCTGGCACTGCTGAACTTTTGCAGCAGCTCTTTCCTCCTCTCTTGGATGCCCTTCGAGA
GCCCAGGTTACGACGGATTTTCTGCCAGCCTGCAGAGAGTTCTATTCTGGGAACTGACATTGACCTTCAGACTATAGACAATGATATCGT
CAGCATGGAGATTTTCTTCAAAGCCTGGCTACATAACAGTGGAACAGACCAAGAACAAATCCATCTTCTTCTTTCTTCACAGTGTTTCAG
CAACATTTCCAGACCCAGAGATAATCCAATGTGTCTGAAATGTGATCTCCAAGAGCGACTGCTCTGCCCATCCCTACTCGCTGGCACAGC
TGACGGCTCCTTGAGAATGGATGACCCTAAAGGAGACTTCATCACACTCTACCAGATGGCTTCCCAGTCATCGGCCTCTCATTACAAGCT
CCAAGTGATCAAGGCTTTAAAATCTAGCGGGCTCTGCGAGTCATTGACATATGGACTCCCGTTCATCCTCAGACCTACAAGCTGTTGGCA
GCTGGACTGGGATGAGCTGGAGACAAATCAGCAACATTTCCATGCTTTGTGTCACAGCCTGCTGAAAAGGGAATGGCTGCTGTTAGCCAA
GGGGGAACCACCGGGCCCAGGACACAGCCAGAGAATTCCTGCCAGCACCTTCTATGTGATCATGCCGTCACACTCCCTCACACTGCTGGT
AAAGGCGGTGGCCACGCGGGAACTGATGCTGCCCAGCACCTTCCCCCTGCTACCTGAGGACCCACATGATGATAGCCTTAAGAATGTGGA
GAGCATGCTGGACAGCCTGGAGCTGGAGCCCACCTACAACCCCTTGCATGTTCAAAGCCACCTGTACTCACACCTGAGCAGCATCTATGC
CAAGCCTCAGGGGCGGCTCCACCCACACTGGGAGAGCCGAGCTCCGAGAAAGACTGGGCAGTTGCAGACCAACCGAGCTCGAGCTACTGT
GGCCCCCCTGCCTATGACTCCTGTCCCAGGCAGAGCCTCCAAGATGCCAGCAGCCAGCAAATCTTCCTCAGATGCCTTCTTCCTGCCTTC
AGAGTGGGAGAAGGATCCCTCAAGGCCCTAAGTCACCAGCACCAGAGCCCAGCTGCCCAGCTTAACCATATCCATGCTCAGGTTCACATA
ATGGCTATCTGTGGTCAGACTTGCTCTCTATCCGCCTGAGCCTCTGTGAGTGAGGGCTGACTGGGAAACAACAGCCTTCCTGTCCTGTTT
CAGTGCTGTCCCACTCCTCAAGTCTGGAAGCGACACACCCGAGCCTGTCCTTTCTCCAGCAAGGACTTTCATTTTCTTTAGAATCATTTG
CTACTGTTTACACAGGTGAAGATTAAACACCCAGTAAGCTTCTACCATTGTTAGGAGCATTCATAACTCAGAATTTCTTCTTGTAGCTCT
GTGTAAGCAGGTGGATGAGGTCAGATCACCTTTGGTAAACTGGACCTCAGGAACAAGGATGAGGTTTTGAAAGCTCATAAAAGACAAGTA
AGATTGAAATCCAAGCCTCATTTCAGAGCCTGTGCCCTTCCCACTACACCACCAGGCTTCAGCCTCCAAAGAGACAAGTGCTTGGTACCT
ACATGCAAAGTGTGTGTGCTGGGGGGTGGGAGGGCTGCCCAGAACAGGGGAGAGGATGGTGTAAAAAAAGACCTACTCCTTTCCTGTTAC
CCTCTCCCCACATGTACCAACCTTCCTGTTGCTCCCTCCATCCACAGAATAATAGCTACCATTTATAAAATGTTTACTCTGGGCTGGGAG
CAGTGGCTCACACCTGTAATCCCAACACTTTGAGAGGCTGAGGTGGGATGATCACTTGAGGCCAGGAGTTCGAGACCAGCCTGAGCAACA

>13641_13641_5_CCDC142-M1AP_CCDC142_chr2_74708350_ENST00000393965_M1AP_chr2_74808974_ENST00000409585_length(amino acids)=769AA_BP=440
MRRALVRAGKWESLGSFWTRRPMAQASRSGSLPPLVIVPPLRAQPGGTGEEQWERSRTGGLRWEVHCWPSGTSGGTPWWPTPADVSEDYE
ADAAAWRRGPAGGGPIPPALQRLRAVLLRLHREREQLLQARDCAYHLQSAVRLMKTLSPGSPSGGPSPLPQWCRDLQLHPSQGAVLRIGP
GETLEPLLLARPIGLAAQCLEAVIEMQLRALGREPASPGLSSQLAELLFALPAYHTLQRKALSHVPGAARPFPTSRVLRLLTGERGCQVA
SRLDEALQGSALRDQLRRRCQEEGDLLPGLLGLVGGVAGSASCGLGLGGAGALWSQYWTLLWAACAQSLDLNLGPWRDPRATAQQLSQAL
GQASLPQECEKELASLCHRLLHQSLIWSWDQGFCQALGSALGGQSSLPTSSGTAELLQQLFPPLLDALREPRLRRIFCQPAESSILGTDI
DLQTIDNDIVSMEIFFKAWLHNSGTDQEQIHLLLSSQCFSNISRPRDNPMCLKCDLQERLLCPSLLAGTADGSLRMDDPKGDFITLYQMA
SQSSASHYKLQVIKALKSSGLCESLTYGLPFILRPTSCWQLDWDELETNQQHFHALCHSLLKREWLLLAKGEPPGPGHSQRIPASTFYVI
MPSHSLTLLVKAVATRELMLPSTFPLLPEDPHDDSLKNVESMLDSLELEPTYNPLHVQSHLYSHLSSIYAKPQGRLHPHWESRAPRKTGQ

--------------------------------------------------------------
>13641_13641_6_CCDC142-M1AP_CCDC142_chr2_74708350_ENST00000393965_M1AP_chr2_74808974_ENST00000536235_length(transcript)=3019nt_BP=1655nt
CTGCATAAAATCCTACTCGAAACGTTCAGACCACAGGTGGACCCAAGAGGGGCTGCCTCTGCCCTCCTAGACCCCCACTGGTCTTGTCAT
ACCGCTCACCTAGCTTGATCCGCCCCACAGTCTTTGGAATCGGCGCCATCGCATCTACAGTGACCCGGAAATGAAAGGTAGTCTAGTATT
TGATACCAGCCAAAGGGCGGGGTGGGACAGAGTGGGCGGCCATGTTTGTTAGGGGCAGAAGCCTCCCATTACGGAGCACGAGAGAGTCCA
TGAAGGTCCCCGCGACTCCCGGACTGGAGAAAACGGCTCTTGCGATGGGGCGAAGTCCGAGCTGCGGCGGGCGTTGGTCCGTGCAGGGAA
GTGGGAATCGTTAGGTTCGTTCTGGACCCGCCGCCCCATGGCCCAGGCGTCTCGCTCAGGTAGCCTGCCTCCACTCGTTATCGTGCCCCC
GCTGAGGGCGCAACCCGGGGGCACTGGGGAGGAGCAGTGGGAGAGAAGTCGAACGGGCGGTCTTCGCTGGGAGGTTCACTGCTGGCCGAG
CGGAACTTCTGGAGGGACGCCGTGGTGGCCGACGCCGGCGGATGTGAGCGAGGACTACGAGGCTGATGCTGCGGCCTGGAGGCGGGGGCC
CGCAGGTGGCGGCCCGATCCCTCCCGCGCTGCAGCGTCTCCGGGCGGTGTTGCTGCGGCTGCATCGCGAGCGGGAGCAGCTCCTCCAGGC
CCGAGACTGCGCCTACCACCTACAGTCGGCTGTGCGACTCATGAAGACCCTGAGTCCTGGCTCGCCATCCGGCGGCCCTAGCCCCTTGCC
CCAGTGGTGCCGCGACCTGCAGCTGCACCCTTCCCAAGGGGCGGTTCTGCGAATCGGCCCTGGGGAGACTCTCGAGCCGCTGCTGCTAGC
GCGCCCCATCGGACTAGCCGCCCAGTGCCTGGAGGCTGTCATCGAGATGCAGCTTCGCGCTCTCGGCCGGGAGCCCGCCAGCCCGGGCCT
GTCGTCCCAACTCGCCGAGCTGCTCTTTGCACTTCCCGCCTACCACACACTACAGAGAAAAGCCTTGAGCCACGTCCCAGGGGCCGCACG
TCCTTTCCCCACGTCCCGTGTGCTCCGCCTCTTGACGGGGGAGCGGGGTTGCCAGGTGGCAAGTCGGCTGGACGAGGCGCTCCAAGGATC
GGCGTTGAGGGACCAGCTCCGCAGGCGGTGCCAAGAGGAGGGGGATCTGCTACCAGGGCTGCTGGGCCTGGTCGGGGGCGTGGCGGGTTC
AGCCAGCTGTGGACTAGGGCTCGGAGGGGCTGGGGCCTTGTGGAGCCAATACTGGACCCTGCTGTGGGCAGCCTGTGCTCAGAGTCTGGA
CCTAAATCTGGGACCCTGGAGGGACCCCAGGGCAACAGCGCAACAGCTGAGTCAGGCACTGGGTCAGGCATCCCTGCCTCAGGAGTGTGA
GAAGGAGCTGGCATCTTTGTGTCACAGACTACTTCATCAGTCGCTTATCTGGAGCTGGGACCAAGGTTTCTGCCAGGCCTTGGGATCAGC
TCTTGGGGGTCAGAGCAGCCTTCCCACATCCTCTGGCACTGCTGAACTTTTGCAGCAGCTCTTTCCTCCTCTCTTGGATGCCCTTCGAGA
GCCCAGGTTACGACGGATTTTCTGCCAGCCTGCAGAGAGTTCTATTCTGGGAACTGACATTGACCTTCAGACTATAGACAATGATATCGT
CAGCATGGAGATTTTCTTCAAAGCCTGGCTACATAACAGTGGAACAGACCAAGAACAAATCCATCTTCTTCTTTCTTCACAGTGTTTCAG
CAACATTTCCAGACCCAGAGATAATCCAATGTGTCTGAAATGTGATCTCCAAGAGCGACTGCTCTGCCCATCCCTACTCGCTGGCACAGC
TGACGGCTCCTTGAGAATGGATGACCCTAAAGGAGACTTCATCACACTCTACCAGATGGCTTCCCAGTCATCGGCCTCTCATTACAAGCT
CCAAGTGATCAAGGCTTTAAAATCTAGCGGGCTCTGCGAGTCATTGACATATGGACTCCCGTTCATCCTCAGACCTACAAGCTGTTGGCA
GCTGGACTGGGATGAGCTGGAGACAAATCAGCAACATTTCCATGCTTTGTGTCACAGCCTGCTGAAAAGGGAATGGCTGCTGTTAGCCAA
GGGGGAACCACCGGGCCCAGGACACAGCCAGAGAATTCCTGCCAGCACCTTCTATGTGATCATGCCGTCACACTCCCTCACACTGCTGGT
AAAGGCGGTGGCCACGCGGGAACTGATGCTGCCCAGCACCTTCCCCCTGCTACCTGAGGACCCACATGATGATAGCCTTAAGAATGTGGA
GAGCATGCTGGACAGCCTGGAGCTGGAGCCCACCTACAACCCCTTGCATGTTCAAAGCCACCTGTACTCACACCTGAGCAGCATCTATGC
CAAGCCTCAGGGGCGGCTCCACCCACACTGGGAGAGCCGAGCTCCGAGAAAGACTGGGCAGTTGCAGACCAACCGAGCTCGAGCTACTGT
GGCCCCCCTGCCTATGACTCCTGTCCCAGGCAGAGCCTCCAAGATGCCAGCAGCCAGCAAATCTTCCTCAGATGCCTTCTTCCTGCCTTC
AGAGTGGGAGAAGGATCCCTCAAGGCCCTAAGTCACCAGCACCAGAGCCCAGCTGCCCAGCTTAACCATATCCATGCTCAGGTTCACATA
ATGGCTATCTGTGGTCAGACTTGCTCTCTATCCGCCTGAGCCTCTGTGAGTGAGGGCTGACTGGGAAACAACAGCCTTCCTGTCCTGTTT
CAGTGCTGTCCCACTCCTCAAGTCTGGAAGCGACACACCCGAGCCTGTCCTTTCTCCAGCAAGGACTTTCATTTTCTTTAGAATCATTTG
CTACTGTTTACACAGGTGAAGATTAAACACCCAGTAAGCTTCTACCATTGTTAGGAGCATTCATAACTCAGAATTTCTTCTTGTAGCTCT

>13641_13641_6_CCDC142-M1AP_CCDC142_chr2_74708350_ENST00000393965_M1AP_chr2_74808974_ENST00000536235_length(amino acids)=769AA_BP=440
MRRALVRAGKWESLGSFWTRRPMAQASRSGSLPPLVIVPPLRAQPGGTGEEQWERSRTGGLRWEVHCWPSGTSGGTPWWPTPADVSEDYE
ADAAAWRRGPAGGGPIPPALQRLRAVLLRLHREREQLLQARDCAYHLQSAVRLMKTLSPGSPSGGPSPLPQWCRDLQLHPSQGAVLRIGP
GETLEPLLLARPIGLAAQCLEAVIEMQLRALGREPASPGLSSQLAELLFALPAYHTLQRKALSHVPGAARPFPTSRVLRLLTGERGCQVA
SRLDEALQGSALRDQLRRRCQEEGDLLPGLLGLVGGVAGSASCGLGLGGAGALWSQYWTLLWAACAQSLDLNLGPWRDPRATAQQLSQAL
GQASLPQECEKELASLCHRLLHQSLIWSWDQGFCQALGSALGGQSSLPTSSGTAELLQQLFPPLLDALREPRLRRIFCQPAESSILGTDI
DLQTIDNDIVSMEIFFKAWLHNSGTDQEQIHLLLSSQCFSNISRPRDNPMCLKCDLQERLLCPSLLAGTADGSLRMDDPKGDFITLYQMA
SQSSASHYKLQVIKALKSSGLCESLTYGLPFILRPTSCWQLDWDELETNQQHFHALCHSLLKREWLLLAKGEPPGPGHSQRIPASTFYVI
MPSHSLTLLVKAVATRELMLPSTFPLLPEDPHDDSLKNVESMLDSLELEPTYNPLHVQSHLYSHLSSIYAKPQGRLHPHWESRAPRKTGQ

--------------------------------------------------------------

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Fusion Gene PPI Analysis for CCDC142-M1AP


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for CCDC142-M1AP


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for CCDC142-M1AP


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource