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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Fusion gene:ARHGEF7-ATP11A (FusionGDB2 ID:HG8874TG23250)

Fusion Gene Summary for ARHGEF7-ATP11A

check button Fusion gene summary
Fusion gene informationFusion gene name: ARHGEF7-ATP11A
Fusion gene ID: hg8874tg23250
HgeneTgene
Gene symbol

ARHGEF7

ATP11A

Gene ID

8874

23250

Gene nameRho guanine nucleotide exchange factor 7ATPase phospholipid transporting 11A
SynonymsBETA-PIX|COOL-1|COOL1|Nbla10314|P50|P50BP|P85|P85COOL1|P85SPR|PAK3|PIXBATPIH|ATPIS
Cytomap('ARHGEF7')('ATP11A')

13q34

13q34

Type of geneprotein-codingprotein-coding
Descriptionrho guanine nucleotide exchange factor 7PAK-interacting exchange factor betaRho guanine nucleotide exchange factor (GEF) 7SH3 domain-containing proline-rich proteinprobable phospholipid-transporting ATPase IHATPase, class VI, type 11AP4-ATPase flippase complex alpha subunit ATP11Aphospholipid-translocating ATPasepotential phospholipid-transporting ATPase IH
Modification date2020032720200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000483189, ENST00000218789, 
ENST00000317133, ENST00000370623, 
ENST00000375723, ENST00000375736, 
ENST00000375737, ENST00000375739, 
ENST00000375741, ENST00000426073, 
ENST00000478679, ENST00000544132, 
Fusion gene scores* DoF score25 X 17 X 12=510014 X 15 X 4=840
# samples 2612
** MAII scorelog2(26/5100*10)=-4.29391371871777
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(12/840*10)=-2.8073549220576
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ARHGEF7 [Title/Abstract] AND ATP11A [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointARHGEF7(111920017)-ATP11A(113459271), # samples:2
Anticipated loss of major functional domain due to fusion event.ARHGEF7-ATP11A seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ARHGEF7-ATP11A seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ARHGEF7-ATP11A seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
ARHGEF7-ATP11A seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
ARHGEF7-ATP11A seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
ARHGEF7-ATP11A seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
ARHGEF7-ATP11A seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneARHGEF7

GO:0043547

positive regulation of GTPase activity

21048939


check buttonFusion gene breakpoints across ARHGEF7 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across ATP11A (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUADTCGA-O1-A52J-01AARHGEF7chr13

111920017

-ATP11Achr13

113459271

+
ChimerDB4LUADTCGA-O1-A52J-01AARHGEF7chr13

111920017

+ATP11Achr13

113459271

+


Top

Fusion Gene ORF analysis for ARHGEF7-ATP11A

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000483189ENST00000283558ARHGEF7chr13

111920017

+ATP11Achr13

113459271

+
3UTR-3CDSENST00000483189ENST00000375630ARHGEF7chr13

111920017

+ATP11Achr13

113459271

+
3UTR-3CDSENST00000483189ENST00000375645ARHGEF7chr13

111920017

+ATP11Achr13

113459271

+
3UTR-3CDSENST00000483189ENST00000487903ARHGEF7chr13

111920017

+ATP11Achr13

113459271

+
3UTR-intronENST00000483189ENST00000419448ARHGEF7chr13

111920017

+ATP11Achr13

113459271

+
5CDS-intronENST00000218789ENST00000419448ARHGEF7chr13

111920017

+ATP11Achr13

113459271

+
5CDS-intronENST00000317133ENST00000419448ARHGEF7chr13

111920017

+ATP11Achr13

113459271

+
5CDS-intronENST00000370623ENST00000419448ARHGEF7chr13

111920017

+ATP11Achr13

113459271

+
5CDS-intronENST00000375723ENST00000419448ARHGEF7chr13

111920017

+ATP11Achr13

113459271

+
5CDS-intronENST00000375736ENST00000419448ARHGEF7chr13

111920017

+ATP11Achr13

113459271

+
5CDS-intronENST00000375737ENST00000419448ARHGEF7chr13

111920017

+ATP11Achr13

113459271

+
5CDS-intronENST00000375739ENST00000419448ARHGEF7chr13

111920017

+ATP11Achr13

113459271

+
5CDS-intronENST00000375741ENST00000419448ARHGEF7chr13

111920017

+ATP11Achr13

113459271

+
5CDS-intronENST00000426073ENST00000419448ARHGEF7chr13

111920017

+ATP11Achr13

113459271

+
5CDS-intronENST00000478679ENST00000419448ARHGEF7chr13

111920017

+ATP11Achr13

113459271

+
5CDS-intronENST00000544132ENST00000419448ARHGEF7chr13

111920017

+ATP11Achr13

113459271

+
Frame-shiftENST00000218789ENST00000283558ARHGEF7chr13

111920017

+ATP11Achr13

113459271

+
Frame-shiftENST00000218789ENST00000375630ARHGEF7chr13

111920017

+ATP11Achr13

113459271

+
Frame-shiftENST00000218789ENST00000375645ARHGEF7chr13

111920017

+ATP11Achr13

113459271

+
Frame-shiftENST00000218789ENST00000487903ARHGEF7chr13

111920017

+ATP11Achr13

113459271

+
Frame-shiftENST00000317133ENST00000283558ARHGEF7chr13

111920017

+ATP11Achr13

113459271

+
Frame-shiftENST00000317133ENST00000375630ARHGEF7chr13

111920017

+ATP11Achr13

113459271

+
Frame-shiftENST00000317133ENST00000375645ARHGEF7chr13

111920017

+ATP11Achr13

113459271

+
Frame-shiftENST00000317133ENST00000487903ARHGEF7chr13

111920017

+ATP11Achr13

113459271

+
Frame-shiftENST00000370623ENST00000283558ARHGEF7chr13

111920017

+ATP11Achr13

113459271

+
Frame-shiftENST00000370623ENST00000375630ARHGEF7chr13

111920017

+ATP11Achr13

113459271

+
Frame-shiftENST00000370623ENST00000375645ARHGEF7chr13

111920017

+ATP11Achr13

113459271

+
Frame-shiftENST00000370623ENST00000487903ARHGEF7chr13

111920017

+ATP11Achr13

113459271

+
Frame-shiftENST00000375723ENST00000283558ARHGEF7chr13

111920017

+ATP11Achr13

113459271

+
Frame-shiftENST00000375723ENST00000375630ARHGEF7chr13

111920017

+ATP11Achr13

113459271

+
Frame-shiftENST00000375723ENST00000375645ARHGEF7chr13

111920017

+ATP11Achr13

113459271

+
Frame-shiftENST00000375723ENST00000487903ARHGEF7chr13

111920017

+ATP11Achr13

113459271

+
Frame-shiftENST00000375736ENST00000283558ARHGEF7chr13

111920017

+ATP11Achr13

113459271

+
Frame-shiftENST00000375736ENST00000375630ARHGEF7chr13

111920017

+ATP11Achr13

113459271

+
Frame-shiftENST00000375736ENST00000375645ARHGEF7chr13

111920017

+ATP11Achr13

113459271

+
Frame-shiftENST00000375736ENST00000487903ARHGEF7chr13

111920017

+ATP11Achr13

113459271

+
Frame-shiftENST00000375737ENST00000283558ARHGEF7chr13

111920017

+ATP11Achr13

113459271

+
Frame-shiftENST00000375737ENST00000375630ARHGEF7chr13

111920017

+ATP11Achr13

113459271

+
Frame-shiftENST00000375737ENST00000375645ARHGEF7chr13

111920017

+ATP11Achr13

113459271

+
Frame-shiftENST00000375737ENST00000487903ARHGEF7chr13

111920017

+ATP11Achr13

113459271

+
Frame-shiftENST00000375739ENST00000283558ARHGEF7chr13

111920017

+ATP11Achr13

113459271

+
Frame-shiftENST00000375739ENST00000375630ARHGEF7chr13

111920017

+ATP11Achr13

113459271

+
Frame-shiftENST00000375739ENST00000375645ARHGEF7chr13

111920017

+ATP11Achr13

113459271

+
Frame-shiftENST00000375739ENST00000487903ARHGEF7chr13

111920017

+ATP11Achr13

113459271

+
Frame-shiftENST00000375741ENST00000283558ARHGEF7chr13

111920017

+ATP11Achr13

113459271

+
Frame-shiftENST00000375741ENST00000375630ARHGEF7chr13

111920017

+ATP11Achr13

113459271

+
Frame-shiftENST00000375741ENST00000375645ARHGEF7chr13

111920017

+ATP11Achr13

113459271

+
Frame-shiftENST00000375741ENST00000487903ARHGEF7chr13

111920017

+ATP11Achr13

113459271

+
Frame-shiftENST00000426073ENST00000283558ARHGEF7chr13

111920017

+ATP11Achr13

113459271

+
Frame-shiftENST00000426073ENST00000375630ARHGEF7chr13

111920017

+ATP11Achr13

113459271

+
Frame-shiftENST00000426073ENST00000375645ARHGEF7chr13

111920017

+ATP11Achr13

113459271

+
Frame-shiftENST00000426073ENST00000487903ARHGEF7chr13

111920017

+ATP11Achr13

113459271

+
Frame-shiftENST00000478679ENST00000283558ARHGEF7chr13

111920017

+ATP11Achr13

113459271

+
Frame-shiftENST00000478679ENST00000375630ARHGEF7chr13

111920017

+ATP11Achr13

113459271

+
Frame-shiftENST00000478679ENST00000375645ARHGEF7chr13

111920017

+ATP11Achr13

113459271

+
Frame-shiftENST00000478679ENST00000487903ARHGEF7chr13

111920017

+ATP11Achr13

113459271

+
In-frameENST00000544132ENST00000283558ARHGEF7chr13

111920017

+ATP11Achr13

113459271

+
In-frameENST00000544132ENST00000375630ARHGEF7chr13

111920017

+ATP11Achr13

113459271

+
In-frameENST00000544132ENST00000375645ARHGEF7chr13

111920017

+ATP11Achr13

113459271

+
In-frameENST00000544132ENST00000487903ARHGEF7chr13

111920017

+ATP11Achr13

113459271

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000544132ARHGEF7chr13111920017+ENST00000283558ATP11Achr13113459271+415090766441491162
ENST00000544132ARHGEF7chr13111920017+ENST00000375630ATP11Achr13113459271+942590766443201218
ENST00000544132ARHGEF7chr13111920017+ENST00000487903ATP11Achr13113459271+951590766441491161
ENST00000544132ARHGEF7chr13111920017+ENST00000375645ATP11Achr13113459271+945290766441491161

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000544132ENST00000283558ARHGEF7chr13111920017+ATP11Achr13113459271+0.0006953230.99930465
ENST00000544132ENST00000375630ARHGEF7chr13111920017+ATP11Achr13113459271+0.0002007390.9997993
ENST00000544132ENST00000487903ARHGEF7chr13111920017+ATP11Achr13113459271+0.0001837990.99981624
ENST00000544132ENST00000375645ARHGEF7chr13111920017+ATP11Achr13113459271+0.0001731340.99982685

Top

Fusion Genomic Features for ARHGEF7-ATP11A


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
ARHGEF7chr13111920017+ATP11Achr13113459270+0.000437360.9995627
ARHGEF7chr13111920017+ATP11Achr13113459270+0.000437360.9995627

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

Top

Fusion Protein Features for ARHGEF7-ATP11A


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr13:111920017/chr13:113459271)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneARHGEF7chr13:111920017chr13:113459271ENST00000317133+919184_243357783.0DomainSH3
HgeneARHGEF7chr13:111920017chr13:113459271ENST00000317133+9191_133357783.0DomainCalponin-homology (CH)
HgeneARHGEF7chr13:111920017chr13:113459271ENST00000370623+719184_243285732.0DomainSH3
HgeneARHGEF7chr13:111920017chr13:113459271ENST00000370623+7191_133285732.0DomainCalponin-homology (CH)
HgeneARHGEF7chr13:111920017chr13:113459271ENST00000375723+7171_133200626.0DomainCalponin-homology (CH)
HgeneARHGEF7chr13:111920017chr13:113459271ENST00000375736+8201_133200647.0DomainCalponin-homology (CH)
HgeneARHGEF7chr13:111920017chr13:113459271ENST00000375739+818184_243328754.0DomainSH3
HgeneARHGEF7chr13:111920017chr13:113459271ENST00000375739+8181_133328754.0DomainCalponin-homology (CH)
HgeneARHGEF7chr13:111920017chr13:113459271ENST00000375741+1020184_243378804.0DomainSH3
HgeneARHGEF7chr13:111920017chr13:113459271ENST00000375741+10201_133378804.0DomainCalponin-homology (CH)
HgeneARHGEF7chr13:111920017chr13:113459271ENST00000426073+8201_133200647.0DomainCalponin-homology (CH)
TgeneATP11Achr13:111920017chr13:113459271ENST000002835581291024_1029541135.0Topological domainCytoplasmic
TgeneATP11Achr13:111920017chr13:113459271ENST000002835581291051_1068541135.0Topological domainExtracellular
TgeneATP11Achr13:111920017chr13:113459271ENST000002835581291094_1134541135.0Topological domainCytoplasmic
TgeneATP11Achr13:111920017chr13:113459271ENST00000283558129111_296541135.0Topological domainCytoplasmic
TgeneATP11Achr13:111920017chr13:113459271ENST00000283558129319_349541135.0Topological domainExtracellular
TgeneATP11Achr13:111920017chr13:113459271ENST00000283558129373_881541135.0Topological domainCytoplasmic
TgeneATP11Achr13:111920017chr13:113459271ENST0000028355812983_88541135.0Topological domainExtracellular
TgeneATP11Achr13:111920017chr13:113459271ENST00000283558129903_914541135.0Topological domainExtracellular
TgeneATP11Achr13:111920017chr13:113459271ENST00000283558129935_964541135.0Topological domainCytoplasmic
TgeneATP11Achr13:111920017chr13:113459271ENST00000283558129987_1000541135.0Topological domainExtracellular
TgeneATP11Achr13:111920017chr13:113459271ENST000003756451301024_1029542857.0Topological domainCytoplasmic
TgeneATP11Achr13:111920017chr13:113459271ENST000003756451301051_1068542857.0Topological domainExtracellular
TgeneATP11Achr13:111920017chr13:113459271ENST000003756451301094_1134542857.0Topological domainCytoplasmic
TgeneATP11Achr13:111920017chr13:113459271ENST00000375645130111_296542857.0Topological domainCytoplasmic
TgeneATP11Achr13:111920017chr13:113459271ENST00000375645130319_349542857.0Topological domainExtracellular
TgeneATP11Achr13:111920017chr13:113459271ENST00000375645130373_881542857.0Topological domainCytoplasmic
TgeneATP11Achr13:111920017chr13:113459271ENST0000037564513083_88542857.0Topological domainExtracellular
TgeneATP11Achr13:111920017chr13:113459271ENST00000375645130903_914542857.0Topological domainExtracellular
TgeneATP11Achr13:111920017chr13:113459271ENST00000375645130935_964542857.0Topological domainCytoplasmic
TgeneATP11Achr13:111920017chr13:113459271ENST00000375645130987_1000542857.0Topological domainExtracellular
TgeneATP11Achr13:111920017chr13:113459271ENST000004879031301024_1029542878.0Topological domainCytoplasmic
TgeneATP11Achr13:111920017chr13:113459271ENST000004879031301051_1068542878.0Topological domainExtracellular
TgeneATP11Achr13:111920017chr13:113459271ENST000004879031301094_1134542878.0Topological domainCytoplasmic
TgeneATP11Achr13:111920017chr13:113459271ENST00000487903130111_296542878.0Topological domainCytoplasmic
TgeneATP11Achr13:111920017chr13:113459271ENST00000487903130319_349542878.0Topological domainExtracellular
TgeneATP11Achr13:111920017chr13:113459271ENST00000487903130373_881542878.0Topological domainCytoplasmic
TgeneATP11Achr13:111920017chr13:113459271ENST0000048790313083_88542878.0Topological domainExtracellular
TgeneATP11Achr13:111920017chr13:113459271ENST00000487903130903_914542878.0Topological domainExtracellular
TgeneATP11Achr13:111920017chr13:113459271ENST00000487903130935_964542878.0Topological domainCytoplasmic
TgeneATP11Achr13:111920017chr13:113459271ENST00000487903130987_1000542878.0Topological domainExtracellular
TgeneATP11Achr13:111920017chr13:113459271ENST000002835581291001_1023541135.0TransmembraneHelical
TgeneATP11Achr13:111920017chr13:113459271ENST000002835581291030_1050541135.0TransmembraneHelical
TgeneATP11Achr13:111920017chr13:113459271ENST000002835581291069_1093541135.0TransmembraneHelical
TgeneATP11Achr13:111920017chr13:113459271ENST00000283558129297_318541135.0TransmembraneHelical
TgeneATP11Achr13:111920017chr13:113459271ENST00000283558129350_372541135.0TransmembraneHelical
TgeneATP11Achr13:111920017chr13:113459271ENST0000028355812962_82541135.0TransmembraneHelical
TgeneATP11Achr13:111920017chr13:113459271ENST00000283558129882_902541135.0TransmembraneHelical
TgeneATP11Achr13:111920017chr13:113459271ENST0000028355812989_110541135.0TransmembraneHelical
TgeneATP11Achr13:111920017chr13:113459271ENST00000283558129915_934541135.0TransmembraneHelical
TgeneATP11Achr13:111920017chr13:113459271ENST00000283558129965_986541135.0TransmembraneHelical
TgeneATP11Achr13:111920017chr13:113459271ENST000003756451301001_1023542857.0TransmembraneHelical
TgeneATP11Achr13:111920017chr13:113459271ENST000003756451301030_1050542857.0TransmembraneHelical
TgeneATP11Achr13:111920017chr13:113459271ENST000003756451301069_1093542857.0TransmembraneHelical
TgeneATP11Achr13:111920017chr13:113459271ENST00000375645130297_318542857.0TransmembraneHelical
TgeneATP11Achr13:111920017chr13:113459271ENST00000375645130350_372542857.0TransmembraneHelical
TgeneATP11Achr13:111920017chr13:113459271ENST0000037564513062_82542857.0TransmembraneHelical
TgeneATP11Achr13:111920017chr13:113459271ENST00000375645130882_902542857.0TransmembraneHelical
TgeneATP11Achr13:111920017chr13:113459271ENST0000037564513089_110542857.0TransmembraneHelical
TgeneATP11Achr13:111920017chr13:113459271ENST00000375645130915_934542857.0TransmembraneHelical
TgeneATP11Achr13:111920017chr13:113459271ENST00000375645130965_986542857.0TransmembraneHelical
TgeneATP11Achr13:111920017chr13:113459271ENST000004879031301001_1023542878.0TransmembraneHelical
TgeneATP11Achr13:111920017chr13:113459271ENST000004879031301030_1050542878.0TransmembraneHelical
TgeneATP11Achr13:111920017chr13:113459271ENST000004879031301069_1093542878.0TransmembraneHelical
TgeneATP11Achr13:111920017chr13:113459271ENST00000487903130297_318542878.0TransmembraneHelical
TgeneATP11Achr13:111920017chr13:113459271ENST00000487903130350_372542878.0TransmembraneHelical
TgeneATP11Achr13:111920017chr13:113459271ENST0000048790313062_82542878.0TransmembraneHelical
TgeneATP11Achr13:111920017chr13:113459271ENST00000487903130882_902542878.0TransmembraneHelical
TgeneATP11Achr13:111920017chr13:113459271ENST0000048790313089_110542878.0TransmembraneHelical
TgeneATP11Achr13:111920017chr13:113459271ENST00000487903130915_934542878.0TransmembraneHelical
TgeneATP11Achr13:111920017chr13:113459271ENST00000487903130965_986542878.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneARHGEF7chr13:111920017chr13:113459271ENST00000317133+919271_451357783.0DomainDH
HgeneARHGEF7chr13:111920017chr13:113459271ENST00000317133+919473_578357783.0DomainPH
HgeneARHGEF7chr13:111920017chr13:113459271ENST00000370623+719271_451285732.0DomainDH
HgeneARHGEF7chr13:111920017chr13:113459271ENST00000370623+719473_578285732.0DomainPH
HgeneARHGEF7chr13:111920017chr13:113459271ENST00000375723+717184_243200626.0DomainSH3
HgeneARHGEF7chr13:111920017chr13:113459271ENST00000375723+717271_451200626.0DomainDH
HgeneARHGEF7chr13:111920017chr13:113459271ENST00000375723+717473_578200626.0DomainPH
HgeneARHGEF7chr13:111920017chr13:113459271ENST00000375736+820184_243200647.0DomainSH3
HgeneARHGEF7chr13:111920017chr13:113459271ENST00000375736+820271_451200647.0DomainDH
HgeneARHGEF7chr13:111920017chr13:113459271ENST00000375736+820473_578200647.0DomainPH
HgeneARHGEF7chr13:111920017chr13:113459271ENST00000375739+818271_451328754.0DomainDH
HgeneARHGEF7chr13:111920017chr13:113459271ENST00000375739+818473_578328754.0DomainPH
HgeneARHGEF7chr13:111920017chr13:113459271ENST00000375741+1020271_451378804.0DomainDH
HgeneARHGEF7chr13:111920017chr13:113459271ENST00000375741+1020473_578378804.0DomainPH
HgeneARHGEF7chr13:111920017chr13:113459271ENST00000426073+820184_243200647.0DomainSH3
HgeneARHGEF7chr13:111920017chr13:113459271ENST00000426073+820271_451200647.0DomainDH
HgeneARHGEF7chr13:111920017chr13:113459271ENST00000426073+820473_578200647.0DomainPH
TgeneATP11Achr13:111920017chr13:113459271ENST000002835581291_61541135.0Topological domainCytoplasmic
TgeneATP11Achr13:111920017chr13:113459271ENST000003756451301_61542857.0Topological domainCytoplasmic
TgeneATP11Achr13:111920017chr13:113459271ENST000004879031301_61542878.0Topological domainCytoplasmic


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Fusion Gene Sequence for ARHGEF7-ATP11A


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>6340_6340_1_ARHGEF7-ATP11A_ARHGEF7_chr13_111920017_ENST00000544132_ATP11A_chr13_113459271_ENST00000283558_length(transcript)=4150nt_BP=907nt
GAGATTGGTGCAGCCCCGGAGGAAGAAAAAAGGGTCTACCCCGAGCCCCGGAGCGAGAGCGAGTGCCTGAGCAACATCCGCGAGTTCCTG
CGCGGCTGCGGGGCTTCCCTGCGGCTGGAGACGTTTGATGCAAATGATTTGTATCAGGGGCAGAATTTTAACAAGGTCCTCAGTTCCTTA
GTGACTCTAAATAAAGTAACAGCAGGACATGACCGATAATAGCAACAATCAACTGGTAGTAAGAGCAAAGTTTAACTTCCAGCAGACCAA
TGAGGACGAGCTTTCCTTCTCAAAAGGAGACGTCATCCATGTCACCCGTGTGGAAGAGGGAGGCTGGTGGGAGGGCACACTCAACGGCCG
GACCGGCTGGTTCCCCAGCAACTACGTGCGCGAGGTCAAGGCCAGCGAGAAGCCTGTGTCTCCCAAATCAGGAACACTGAAGAGCCCTCC
CAAAGGATTTGATACGACTGCCATAAACAAAAGCTATTACAATGTGCCAGTACTTAGCCGCGGAGCGGAAAGCAGTGCTCATGAAGGTGG
AGGCACACCCAGAGACTGCATGGAGGTGGAACCGGGAAGTCCGGGGTCTGAGGTCCTGCCTGCAGGGTTGAAAGGCATGCCTGCCAGCAG
ACACATTTGGGAGCCAGAGTGTGCTGTGGTCTGAATGTGTTTCCCCAGATCATCTGTTACTACAGATGATCACCAATTGGATGGTATTAA
AAGCACACGTGCCCCTGCTCCGGGTTGTTGCTGTTGTCCTTCAGAAACTCTGAGGTCTGGAGAGGTTGCCCGAAGCTCAGCAGAGAGTCG
GAGGCTGCTTTTTAAACCTGATGCCACAGATGAAAACCCTGTACCTCACGTATTGTGCCAATCACCCTTCTGCAGTGAATGTCCTCACGG
AACACAGTACACATTTTGGAACTTTATACCCAAGAATTTATTTGAACAATTCAGAAGAGTAGCCAACTTTTATTTCCTTATCATATTTCT
GGTGCAGTTGATTATTGATACACCCACAAGTCCAGTGACAAGCGGACTTCCACTCTTCTTTGTCATTACTGTGACGGCTATCAAACAGGG
TTATGAAGACTGGCTTCGACATAAAGCAGACAATGCCATGAACCAGTGTCCTGTTCATTTCATTCAGCACGGCAAGCTCGTTCGGAAACA
AAGTCGAAAGCTGCGAGTTGGGGACATTGTCATGGTTAAGGAGGACGAGACCTTTCCCTGCGACTTGATCTTCCTTTCCAGCAACCGGGG
AGATGGGACGTGCCACGTCACCACCGCCAGCTTGGATGGAGAATCCAGCCATAAAACGCATTACGCGGTCCAGGACACCAAAGGCTTCCA
CACAGAGGAGGATATCGGCGGACTTCACGCCACCATCGAGTGTGAGCAGCCCCAGCCCGACCTCTACAAGTTCGTGGGTCGCATCAACGT
TTACAGTGACCTGAATGACCCCGTGGTGAGGCCCTTAGGATCGGAAAACCTGCTGCTTAGAGGAGCTACACTGAAGAACACTGAGAAAAT
CTTTGGTGTGGCTATTTACACGGGAATGGAAACCAAGATGGCATTAAATTATCAATCAAAATCTCAGAAGCGATCTGCCGTGGAAAAATC
GATGAATGCGTTCCTCATTGTGTATCTCTGCATTCTGATCAGCAAAGCCCTGATAAACACTGTGCTGAAATACATGTGGCAGAGTGAGCC
CTTTCGGGATGAGCCGTGGTATAATCAGAAAACGGAGTCGGAAAGGCAGAGGAATCTGTTCCTCAAGGCATTCACGGACTTCCTGGCCTT
CATGGTCCTCTTTAACTACATCATCCCTGTGTCCATGTACGTCACGGTCGAGATGCAGAAGTTCCTCGGCTCTTACTTCATCACCTGGGA
CGAAGACATGTTTGACGAGGAGACTGGCGAGGGGCCTCTGGTGAACACGTCGGACCTCAATGAAGAGCTGGGACAGGTGGAGTACATCTT
CACAGACAAGACCGGCACCCTCACGGAAAACAACATGGAGTTCAAGGAGTGCTGCATCGAAGGCCATGTCTACGTGCCCCACGTCATCTG
CAACGGGCAGGTCCTCCCAGAGTCGTCAGGAATCGACATGATTGACTCGTCCCCCAGCGTCAACGGGAGGGAGCGCGAGGAGCTGTTTTT
CCGGGCCCTCTGTCTCTGCCACACCGTCCAGGTGAAAGACGATGACAGCGTAGACGGCCCCAGGAAATCGCCGGACGGGGGGAAATCCTG
TGTGTACATCTCATCCTCGCCCGACGAGGTGGCGCTGGTCGAAGGTGTCCAGAGACTTGGCTTTACCTACCTAAGGCTGAAGGACAATTA
CATGGAGATATTAAACAGGGAGAACCACATCGAAAGGTTTGAATTGCTGGAAATTTTGAGTTTTGACTCAGTCAGAAGGAGAATGAGTGT
AATTGTAAAATCTGCTACAGGAGAAATTTATCTGTTTTGCAAAGGAGCAGATTCTTCGATATTCCCCCGAGTGATAGAAGGCAAAGTTGA
CCAGATCCGAGCCAGAGTGGAGCGTAACGCAGTGGAGGGGCTCCGAACTTTGTGTGTTGCTTATAAAAGGCTGATCCAAGAAGAATATGA
AGGCATTTGTAAGCTGCTGCAGGCTGCCAAAGTGGCCCTTCAAGATCGAGAGAAAAAGTTAGCAGAAGCCTATGAGCAAATAGAGAAAGA
TCTTACTCTGCTTGGTGCTACAGCTGTTGAGGACCGGCTGCAGGAGAAAGCTGCAGACACCATCGAGGCCCTGCAGAAGGCCGGGATCAA
AGTCTGGGTTCTCACGGGAGACAAGATGGAGACGGCCGCGGCCACGTGCTACGCCTGCAAGCTCTTCCGCAGGAACACGCAGCTGCTGGA
GCTGACCACCAAGAGGATCGAGGAGCAGAGCCTGCACGACGTCCTGTTCGAGCTGAGCAAGACGGTCCTGCGCCACAGCGGGAGCCTGAC
CAGAGACAACCTGTCCGGACTTTCAGCAGATATGCAGGACTACGGTTTAATTATCGACGGAGCTGCACTGTCTCTGATAATGAAGCCTCG
AGAAGACGGGAGTTCCGGCAACTACAGGGAGCTCTTCCTGGAAATCTGCCGGAGCTGCAGCGCGGTGCTCTGCTGCCGCATGGCGCCCTT
GCAGAAGGCTCAGATTGTTAAATTAATCAAATTTTCAAAAGAGCACCCAATCACGTTAGCAATTGGCGATGGTGCAAATGATGTCAGCAT
GATTCTGGAAGCGCACGTGGGCATAGGTGTCATCGGCAAGGAAGGCCGCCAGGCTGCCAGGAACAGCGACTATGCAATCCCAAAGTTTAA
GCATTTGAAGAAGATGCTGCTTGTTCACGGGCATTTTTATTACATTAGGATCTCTGAGCTCGTGCAGTACTTCTTCTATAAGAACGTCTG
CTTCATCTTCCCTCAGTTTTTATACCAGTTCTTCTGTGGGTTTTCACAACAGACTTTGTACGACACCGCGTATCTGACCCTCTACAACAT
CAGCTTCACCTCCCTCCCCATCCTCCTGTACAGCCTCATGGAGCAGCATGTTGGCATTGACGTGCTCAAGAGAGACCCGACCCTGTACAG
GGACGTCGCCAAGAATGCCCTGCTGCGCTGGCGCGTGTTCATCTACTGGACGCTCCTGGGACTGTTTGACGCACTGGTGTTCTTCTTTGG
TGCTTATTTCGTGTTTGAAAATACAACTGTGACAAGCAACGGGCAGATATTTGGAAACTGGACGTTTGGAACGCTGGTATTCACCGTGAT
GGTGTTCACAGTTACACTAAAGCTTGCATTGGACACACACTACTGGACTTGGATCAACCATTTTGTCATCTGGGGGTCGCTGCTGTTCTA
CGTTGTCTTTTCGCTTCTCTGGGGAGGAGTGATCTGGCCGTTCCTCAACTACCAGAGGATGTACTACGTGTTCATCCAGATGCTGTCCAG
CGGGCCCGCCTGGCTGGCCATCGTGCTGCTGGTGACCATCAGCCTCCTTCCCGACGTCCTCAAGAAAGTCCTGTGCCGGCAGCTGTGGCC
AACAGCAACAGAGAGAGTCCAGACTAAGAGCCAGTGCCTTTCTGTCGAGCAGTCAACCATCTTTATGCTTTCTCAGACTTCCAGCAGCCT

>6340_6340_1_ARHGEF7-ATP11A_ARHGEF7_chr13_111920017_ENST00000544132_ATP11A_chr13_113459271_ENST00000283558_length(amino acids)=1162AA_BP=80
MCFPRSSVTTDDHQLDGIKSTRAPAPGCCCCPSETLRSGEVARSSAESRRLLFKPDATDENPVPHVLCQSPFCSECPHGTQYTFWNFIPK
NLFEQFRRVANFYFLIIFLVQLIIDTPTSPVTSGLPLFFVITVTAIKQGYEDWLRHKADNAMNQCPVHFIQHGKLVRKQSRKLRVGDIVM
VKEDETFPCDLIFLSSNRGDGTCHVTTASLDGESSHKTHYAVQDTKGFHTEEDIGGLHATIECEQPQPDLYKFVGRINVYSDLNDPVVRP
LGSENLLLRGATLKNTEKIFGVAIYTGMETKMALNYQSKSQKRSAVEKSMNAFLIVYLCILISKALINTVLKYMWQSEPFRDEPWYNQKT
ESERQRNLFLKAFTDFLAFMVLFNYIIPVSMYVTVEMQKFLGSYFITWDEDMFDEETGEGPLVNTSDLNEELGQVEYIFTDKTGTLTENN
MEFKECCIEGHVYVPHVICNGQVLPESSGIDMIDSSPSVNGREREELFFRALCLCHTVQVKDDDSVDGPRKSPDGGKSCVYISSSPDEVA
LVEGVQRLGFTYLRLKDNYMEILNRENHIERFELLEILSFDSVRRRMSVIVKSATGEIYLFCKGADSSIFPRVIEGKVDQIRARVERNAV
EGLRTLCVAYKRLIQEEYEGICKLLQAAKVALQDREKKLAEAYEQIEKDLTLLGATAVEDRLQEKAADTIEALQKAGIKVWVLTGDKMET
AAATCYACKLFRRNTQLLELTTKRIEEQSLHDVLFELSKTVLRHSGSLTRDNLSGLSADMQDYGLIIDGAALSLIMKPREDGSSGNYREL
FLEICRSCSAVLCCRMAPLQKAQIVKLIKFSKEHPITLAIGDGANDVSMILEAHVGIGVIGKEGRQAARNSDYAIPKFKHLKKMLLVHGH
FYYIRISELVQYFFYKNVCFIFPQFLYQFFCGFSQQTLYDTAYLTLYNISFTSLPILLYSLMEQHVGIDVLKRDPTLYRDVAKNALLRWR
VFIYWTLLGLFDALVFFFGAYFVFENTTVTSNGQIFGNWTFGTLVFTVMVFTVTLKLALDTHYWTWINHFVIWGSLLFYVVFSLLWGGVI

--------------------------------------------------------------
>6340_6340_2_ARHGEF7-ATP11A_ARHGEF7_chr13_111920017_ENST00000544132_ATP11A_chr13_113459271_ENST00000375630_length(transcript)=9425nt_BP=907nt
GAGATTGGTGCAGCCCCGGAGGAAGAAAAAAGGGTCTACCCCGAGCCCCGGAGCGAGAGCGAGTGCCTGAGCAACATCCGCGAGTTCCTG
CGCGGCTGCGGGGCTTCCCTGCGGCTGGAGACGTTTGATGCAAATGATTTGTATCAGGGGCAGAATTTTAACAAGGTCCTCAGTTCCTTA
GTGACTCTAAATAAAGTAACAGCAGGACATGACCGATAATAGCAACAATCAACTGGTAGTAAGAGCAAAGTTTAACTTCCAGCAGACCAA
TGAGGACGAGCTTTCCTTCTCAAAAGGAGACGTCATCCATGTCACCCGTGTGGAAGAGGGAGGCTGGTGGGAGGGCACACTCAACGGCCG
GACCGGCTGGTTCCCCAGCAACTACGTGCGCGAGGTCAAGGCCAGCGAGAAGCCTGTGTCTCCCAAATCAGGAACACTGAAGAGCCCTCC
CAAAGGATTTGATACGACTGCCATAAACAAAAGCTATTACAATGTGCCAGTACTTAGCCGCGGAGCGGAAAGCAGTGCTCATGAAGGTGG
AGGCACACCCAGAGACTGCATGGAGGTGGAACCGGGAAGTCCGGGGTCTGAGGTCCTGCCTGCAGGGTTGAAAGGCATGCCTGCCAGCAG
ACACATTTGGGAGCCAGAGTGTGCTGTGGTCTGAATGTGTTTCCCCAGATCATCTGTTACTACAGATGATCACCAATTGGATGGTATTAA
AAGCACACGTGCCCCTGCTCCGGGTTGTTGCTGTTGTCCTTCAGAAACTCTGAGGTCTGGAGAGGTTGCCCGAAGCTCAGCAGAGAGTCG
GAGGCTGCTTTTTAAACCTGATGCCACAGATGAAAACCCTGTACCTCACGTATTGTGCCAATCACCCTTCTGCAGTGAATGTCCTCACGG
AACACAGTACACATTTTGGAACTTTATACCCAAGAATTTATTTGAACAATTCAGAAGAGTAGCCAACTTTTATTTCCTTATCATATTTCT
GGTGCAGTTGATTATTGATACACCCACAAGTCCAGTGACAAGCGGACTTCCACTCTTCTTTGTCATTACTGTGACGGCTATCAAACAGGG
TTATGAAGACTGGCTTCGACATAAAGCAGACAATGCCATGAACCAGTGTCCTGTTCATTTCATTCAGCACGGCAAGCTCGTTCGGAAACA
AAGTCGAAAGCTGCGAGTTGGGGACATTGTCATGGTTAAGGAGGACGAGACCTTTCCCTGCGACTTGATCTTCCTTTCCAGCAACCGGGG
AGATGGGACGTGCCACGTCACCACCGCCAGCTTGGATGGAGAATCCAGCCATAAAACGCATTACGCGGTCCAGGACACCAAAGGCTTCCA
CACAGAGGAGGATATCGGCGGACTTCACGCCACCATCGAGTGTGAGCAGCCCCAGCCCGACCTCTACAAGTTCGTGGGTCGCATCAACGT
TTACAGTGACCTGAATGACCCCGTGGTGAGGCCCTTAGGATCGGAAAACCTGCTGCTTAGAGGAGCTACACTGAAGAACACTGAGAAAAT
CTTTGGTGTGGCTATTTACACGGGAATGGAAACCAAGATGGCATTAAATTATCAATCAAAATCTCAGAAGCGATCTGCCGTGGAAAAATC
GATGAATGCGTTCCTCATTGTGTATCTCTGCATTCTGATCAGCAAAGCCCTGATAAACACTGTGCTGAAATACATGTGGCAGAGTGAGCC
CTTTCGGGATGAGCCGTGGTATAATCAGAAAACGGAGTCGGAAAGGCAGAGGAATCTGTTCCTCAAGGCATTCACGGACTTCCTGGCCTT
CATGGTCCTCTTTAACTACATCATCCCTGTGTCCATGTACGTCACGGTCGAGATGCAGAAGTTCCTCGGCTCTTACTTCATCACCTGGGA
CGAAGACATGTTTGACGAGGAGACTGGCGAGGGGCCTCTGGTGAACACGTCGGACCTCAATGAAGAGCTGGGACAGGTGGAGTACATCTT
CACAGACAAGACCGGCACCCTCACGGAAAACAACATGGAGTTCAAGGAGTGCTGCATCGAAGGCCATGTCTACGTGCCCCACGTCATCTG
CAACGGGCAGGTCCTCCCAGAGTCGTCAGGAATCGACATGATTGACTCGTCCCCCAGCGTCAACGGGAGGGAGCGCGAGGAGCTGTTTTT
CCGGGCCCTCTGTCTCTGCCACACCGTCCAGGTGAAAGACGATGACAGCGTAGACGGCCCCAGGAAATCGCCGGACGGGGGGAAATCCTG
TGTGTACATCTCATCCTCGCCCGACGAGGTGGCGCTGGTCGAAGGTGTCCAGAGACTTGGCTTTACCTACCTAAGGCTGAAGGACAATTA
CATGGAGATATTAAACAGGGAGAACCACATCGAAAGGTTTGAATTGCTGGAAATTTTGAGTTTTGACTCAGTCAGAAGGAGAATGAGTGT
AATTGTAAAATCTGCTACAGGAGAAATTTATCTGTTTTGCAAAGGAGCAGATTCTTCGATATTCCCCCGAGTGATAGAAGGCAAAGTTGA
CCAGATCCGAGCCAGAGTGGAGCGTAACGCAGTGGAGGGGCTCCGAACTTTGTGTGTTGCTTATAAAAGGCTGATCCAAGAAGAATATGA
AGGCATTTGTAAGCTGCTGCAGGCTGCCAAAGTGGCCCTTCAAGATCGAGAGAAAAAGTTAGCAGAAGCCTATGAGCAAATAGAGAAAGA
TCTTACTCTGCTTGGTGCTACAGCTGTTGAGGACCGGCTGCAGGAGAAAGCTGCAGACACCATCGAGGCCCTGCAGAAGGCCGGGATCAA
AGTCTGGGTTCTCACGGGAGACAAGATGGAGACGGCCGCGGCCACGTGCTACGCCTGCAAGCTCTTCCGCAGGAACACGCAGCTGCTGGA
GCTGACCACCAAGAGGATCGAGGAGCAGAGCCTGCACGACGTCCTGTTCGAGCTGAGCAAGACGGTCCTGCGCCACAGCGGGAGCCTGAC
CAGAGACAACCTGTCCGGACTTTCAGCAGATATGCAGGACTACGGTTTAATTATCGACGGAGCTGCACTGTCTCTGATAATGAAGCCTCG
AGAAGACGGGAGTTCCGGCAACTACAGGGAGCTCTTCCTGGAAATCTGCCGGAGCTGCAGCGCGGTGCTCTGCTGCCGCATGGCGCCCTT
GCAGAAGGCTCAGATTGTTAAATTAATCAAATTTTCAAAAGAGCACCCAATCACGTTAGCAATTGGCGATGGTGCAAATGATGTCAGCAT
GATTCTGGAAGCGCACGTGGGCATAGGTGTCATCGGCAAGGAAGGCCGCCAGGCTGCCAGGAACAGCGACTATGCAATCCCAAAGTTTAA
GCATTTGAAGAAGATGCTGCTTGTTCACGGGCATTTTTATTACATTAGGATCTCTGAGCTCGTGCAGTACTTCTTCTATAAGAACGTCTG
CTTCATCTTCCCTCAGTTTTTATACCAGTTCTTCTGTGGGTTTTCACAACAGACTTTGTACGACACCGCGTATCTGACCCTCTACAACAT
CAGCTTCACCTCCCTCCCCATCCTCCTGTACAGCCTCATGGAGCAGCATGTTGGCATTGACGTGCTCAAGAGAGACCCGACCCTGTACAG
GGACGTCGCCAAGAATGCCCTGCTGCGCTGGCGCGTGTTCATCTACTGGACGCTCCTGGGACTGTTTGACGCACTGGTGTTCTTCTTTGG
TGCTTATTTCGTGTTTGAAAATACAACTGTGACAAGCAACGGGCAGATATTTGGAAACTGGACGTTTGGAACGCTGGTATTCACCGTGAT
GGTGTTCACAGTTACACTAAAGCTTGCATTGGACACACACTACTGGACTTGGATCAACCATTTTGTCATCTGGGGGTCGCTGCTGTTCTA
CGTTGTCTTTTCGCTTCTCTGGGGAGGAGTGATCTGGCCGTTCCTCAACTACCAGAGGATGTACTACGTGTTCATCCAGATGCTGTCCAG
CGGGCCCGCCTGGCTGGCCATCGTGCTGCTGGTGACCATCAGCCTCCTTCCCGACGTCCTCAAGAAAGTCCTGTGCCGGCAGCTGTGGCC
AACAGCAACAGAGAGAGTCCAGAATGGGTGCGCACAGCCTCGGGACCGCGACTCAGAATTCACCCCTCTTGCCTCTCTGCAGAGCCCAGG
CTACCAGAGCACCTGTCCCTCGGCCGCCTGGTACAGCTCCCACTCTCAGCAGGTGACACTCGCGGCCTGGAAGGAGAAGGTGTCCACGGA
GCCCCCACCCATCCTCGGCGGTTCCCATCACCACTGCAGTTCCATCCCAAGTCACAGCTGCCCTAGGTCCCGTGTGGGAATGCTCGTGTG
ATGGATGGTCCTAAGCCTGTGGAGACTGTGCACGTGCCTCTTCCTGGCCCCCAGCAGGCAAGGAGGGGGGTCACAGGCCTTGCCCTCGAG
CATGGCACCCTGGCCGCCTGGACCCAGCACTGTGGTTGTTGAGCCACACCAGTGGCCTCTGGGCATTCGGCTCAACGCAGGAGGGACATT
CTGCTGGCCCACCCTGCGCGCTGTCATGCAGAGGCCATTCCCCCAGGCCTGTGTCTTCACCCACCTGCCATCATTGGCCTTTGCTGTCAC
TGGGAGAGAAGAGCCGTCCAGGGACCCATGGTGGCCCACATGTGGATGCCACATGCTGCTGTTTCCTGCTTGCCCGGCCACCACCCATGC
CCTCCATAGGGTGAGGTGGAGCCATGGTGGTGCGTCCTTTACTCAACAACCCTCCAATCCGGATGCTGTGGGAAGGGCCGGGTCACTCGG
ATACCATCATCCCTGCGGATGCACCGCCGTACCCTGCTCATCTGGGAGTGGTTTCCCTGCGGTTACGTCCAAGCCCGCCTGCCCTGTGTG
TTGGGGCTGGCTGAGTTTCGGTCTCCCCATCACCGGCCGCCTCGTGGAGAAGGCAGTGCCACGTGGGAGGACAAGGCCACGCCGGCAGCT
TCCAGCCCTGCCGCAGAAGTGCCAGGATGTCCATCAGCCACTCGCCAGGGCACGGAGCCGTCAGTCCACTGTTACGGGAGAATGTTGATT
TCGCGGGTGCGAGGGCCGGGAGACAGATACTTGGCTGTGATGAGCAGACATCCTCTGTCCCCGTGGAGGGGTCAACACCAAGGTGGTGTT
CGTGCACCAGAACCTGTCTCGGGCTGACGGGGGTGGCACACAGGACACGGGTGGATCCCAACAGGCAGCACCGCACCTCTGCCCGCCTCC
CGCACTGCAGCTCCGCCCGCCGGGCTCTGCGTCCCCACGTCCCCTCGTCCCATCCCCACGTCCCCTCATCCCGTCACCTCGTCCCCACAT
CCCCTTGCCCCGTCACCTCGTCCTCATGTCCCCTTGTCCTGTCACCTCGTCCCCACGTCCCCTCGTCTCCTCATCCCCACGTCCTCTCGT
CCCCTTGTCCCGTCCCCACATACCCTCGTCCCCATGTCCCCACGCAGGGCTCTCCTTCGTCTTAGGATCTGTCCAGCGCTGCTCTGGGTG
GGTTAGCAACCCCAGGGCTGCTGTGATAGGAAGTCCCTGTTGTTCTCCGTACTGGCATTTCTATTTCTAGAAATAATATTTGACATAGCC
TTAATGGTCCTTAAAGAAGACATTTCAGTGTGAGATTCAGACTTCAGACGCTGAAACTGCTGCCTTTCAGGAAAGCACCACCAACGCTGG
AGGAGGAGCCGGCCCTCACGCCCGCCCCGCGCCACGCTGTGGAACGGGGCTCCGGCAAGTGAAACCCAGAGGGTGTTTCCGAGGTGCTCG
ACAGTAGGTATTTTTGGAAGCTCAGATTTCACCATTTGATTGTATAATCTTTTACCTATAAAATATTTATTTGAAGTAGAGGGTAAATCA
GCGGTAAGAACAGTGAACACAGTGGTTGGGATAAAATAAGGTGACAAACATCACACCAAAGATGAGGGTAGCGAGCAACTGGCTTGAGCA
GACAGAACGGGGAAGACTCCACTCTGTCCCGAGGGGCCAGCCGCAGGCGTCCCCAGGGCCACCCTGCCCTGAGGTCCTTGTGTGGCCGCC
CTGGCTTGGCAGCCCTGCCCACGCTGCCCCCGCAAACAATGGTGTGTGCGTTTTTACAGCCCTTTTTAGGAACCCAATATGGGCATAAAT
GTAACACCTGTAGCGGGGGCAGATTCTCTGTATGTTCAGTTAACAAATTATTTGTAATGTATTTTTTTAGAAATCTTAAAATTGCCTTTG
CACTGAAGTATTTTCATAGCTGTTTATATCTCTTTTATTCATTTATTTAACATACTGTCTAATTTTAAAAATAGGTTTTTAAAGCTTTCA
TTTTTAAGTTTATGAAATTTTGGCCACTTTACATTTAGATTCTGGTGAGAGTTTTGACTGAATGTTCCAATCTCTGATGAATGCGAATTT
TCAGATTTGATTTTATTCTCTACACACACCTCTTCTTTTCTTGGTATTTCTGGTGGCAGTGATTAGTTGAACAGCACATTTAAGGCACGA
TAATTTGCTACACTTTTTCTTTACAATTTGTTGCAATTTCATCTGCTTTCTATGTTTCATTGTTAATTGCCATCCTTCAGCCTTAAAAAT
AGAAGATTCTCACGTGAAGGTTTAGTAAGTTGGGTCCCAGCTCTGCCTGTGTGGAGATAGTCACCATGTACCTCTGACAACAAGTTTTAG
TGTGAAAGTCACTAAACTTTTACACACTCCCAAACGTCTTTTTAAAAATTGCTTGGGAAATTATTAAATGAATGTGCCTGATGATTTGAA
ATAGACAAGGGGCACGAGATAAAAAAGAAAAGGATGAGAAGATCCTCAGTGAATGACGTTGCAGGGTCTTCATGCAATTTTCCACCTCGC
AGTAGTTAGTATTTACTTGCCTTAAACTAACTTTGAAGCAAGTAATGTCAACTTTGAGCACTTTGTTGAGTTTTGAAAAATCTTATTTGT
TGCTGCACAGGTTAATAAATTATCAATTTGTAATTCAGCATGTTGGTCAGAGACACGGTCACTGATTCACACCCAGTCCCTGCCACAGAC
CGTCTCAGACACGCACAGTGGGCCTGCTGCATGATTCACACCCAGTCCCTGCCACAGACCGTCTCAGACACGCACAGTGGGCCTGCTGCA
TGATTCACACCCAGTCCCTGCCACAGACCGTCTCAGACACGCACAGTGGGCCTGCTGCATGCGTGTTACCTGGCTTTTGGCTCCACGCTC
ACTCATAGCCATGTCCACATGGGGGCTTGCACACAGGATCACTCACATATGTACATGTACCCACCACAAACGTGCAAGCTCCTGCACACA
TGCATGCACACAAACGTGTACACAAGTGTGAGCTCCTACACGCATACACACACACACGTGTACATGCACCAAAGCATGTGTGACCTACAG
ACATGCAGAACATGCACGTGTACACATACCACAGACACGCGTGTGCATGCTCCTACACAATACATATGCACATATCATGAACAGCGTAAG
TTCCTACACACGGACGTGTGATACACACATGCATGTACAGGTAAGCACACATGTACAAGCTCCTACAGGCTTGCTCTCACACACGTGTAT
GCACAGCAGAGAGACGTATGAGCTTCTACTGCACACATGCACACACACACGCACACGTACATTCACTACAAACGTGCAGCCTCCTGCACA
CGTGCACATTCATGTGTACACCACAAATGAGTTCCCAGACGTGTAAACACACGTGCACACATCGTACACATGTGAGCTCCCACACGTACA
CACAGATGCACATGGACACACCCCAAACACGCACAGGCTCCTACACACATGCACACACGTGTACACCACAAACGAGCTCCCAGACATGTA
AACACACGTCTCCCACACGTGAGCTCCCACACGTACACATGCACATGTACGCACCACAAACACATGCGCAGGCTCCTGCAGGCGTGAATA
CACACATGCACACACATATACACACATGTGCCACAAACAAGTGCACACTGTCCTGGTGTCCTGCACTGCATCCTGCCTCCTTGCTGAGGG
GCCCCTGTGAGAGGCCTCTGGATGGGCATGGGAAGATGGGCTCCCTGGCCCCCAGCCCATGCCTCCCTGGGATGAAGAGTCCCCCTCCTG
GCAGAATGTCTGGGCTTTGCAGAGCAGGCCCCGGGGGTGAAGTCGCAGCTTCACTTACACCAGCTGCTCTGTGAGCAAGGCTTGGTGCCC
TGGACAAGGCCCTTCCCCTTTAGGGAGGTCCAGCCTCGCAAGCTGAAACCTCCCCTCGGCTCAGCCCTATACCAGGCGGCCACAGCAGGA
CTGGCCACACCCACGCCGCACCTCATCCGTGCACGCGTCGGAGCACGGCCAGCCTTCCGCCACGAGCCAGCTGGGAAGGGCCGCGGCCGC
CTAAAGCCCCAGTCAACCCAGCCTGTGTCTGAGCAGACAGGGCGAACAAGCAGGCCACACCGTCTCGAGGGAGGAGGCCAGATGCGGCCA
GCGTCTCCAACAGGGTGACCATCCGCTCGGCTTGCTGAGCGTTTAAACAAATGTTTAGACAGGCTGTGGGGACTCCCCTGAGTTGAGCCT
TGGCCAGGGGTCCGGTGCTGTCGCGGGAAACCTCCAGCCTTGTTCTTCAAACCACTCAGCTCATGTGTTTTGCACTGACTAGTACTGAAT
AATACAACCACTCTTATTTAATGTTAGTATTATTTATTTGACAACTCAGTGTCTAACAGCTTGATATGCAGGTCCTTGCATCCTACATTT
CTTTAGGAAGTTACCCATTTGTAACTTTAAAAACAGGAAAAATATCAGTTGGCAAATGCAATCTTTTTTTTTTTTAAGCTAAAGGTGGGT
GAACTGGAATGAAAATCTTTCTGATGTTGTGTCTATAAGCAGCCTTGATGGGATATGTTAGAAGTGTCATGAAAGTGTGATTCTACTTTT
GCAGAAAAATCTAAAGATCAATTTATATAGCTTTATTTTTTACTTTATCAAAGTATACAGAATTTTAATATGCATATATTGTGTCTGACT
TAAAATTATAATGTCTGCGTCACCATTTAAAATGTCTGTTCATTATGTAATGTAATAAAAGAAGGTCTTCAAAAATGTATTTAACATGAA
TGGTATCCATAGTTGTCATCATCATAAATACTGGAGTTTATTTTTAAATTATTAAACATAGTAGGTGCATTAACATAAATCAGTCTCCAC
ACAGTAACATTTAACTGATAATTCATTAATCAGCTTTGAAAAATTAAATTGTTAATTAAACCAATCTAACATTTCAGTAAAGTTTATTTT
GTATGCTTCTGTTTTTAACTTTTATTTCTGTAGATAAACTGACTGGATAATATTATATTGGACTTTTCTCTAGATTATCTAAGCAGGAGA

>6340_6340_2_ARHGEF7-ATP11A_ARHGEF7_chr13_111920017_ENST00000544132_ATP11A_chr13_113459271_ENST00000375630_length(amino acids)=1218AA_BP=80
MCFPRSSVTTDDHQLDGIKSTRAPAPGCCCCPSETLRSGEVARSSAESRRLLFKPDATDENPVPHVLCQSPFCSECPHGTQYTFWNFIPK
NLFEQFRRVANFYFLIIFLVQLIIDTPTSPVTSGLPLFFVITVTAIKQGYEDWLRHKADNAMNQCPVHFIQHGKLVRKQSRKLRVGDIVM
VKEDETFPCDLIFLSSNRGDGTCHVTTASLDGESSHKTHYAVQDTKGFHTEEDIGGLHATIECEQPQPDLYKFVGRINVYSDLNDPVVRP
LGSENLLLRGATLKNTEKIFGVAIYTGMETKMALNYQSKSQKRSAVEKSMNAFLIVYLCILISKALINTVLKYMWQSEPFRDEPWYNQKT
ESERQRNLFLKAFTDFLAFMVLFNYIIPVSMYVTVEMQKFLGSYFITWDEDMFDEETGEGPLVNTSDLNEELGQVEYIFTDKTGTLTENN
MEFKECCIEGHVYVPHVICNGQVLPESSGIDMIDSSPSVNGREREELFFRALCLCHTVQVKDDDSVDGPRKSPDGGKSCVYISSSPDEVA
LVEGVQRLGFTYLRLKDNYMEILNRENHIERFELLEILSFDSVRRRMSVIVKSATGEIYLFCKGADSSIFPRVIEGKVDQIRARVERNAV
EGLRTLCVAYKRLIQEEYEGICKLLQAAKVALQDREKKLAEAYEQIEKDLTLLGATAVEDRLQEKAADTIEALQKAGIKVWVLTGDKMET
AAATCYACKLFRRNTQLLELTTKRIEEQSLHDVLFELSKTVLRHSGSLTRDNLSGLSADMQDYGLIIDGAALSLIMKPREDGSSGNYREL
FLEICRSCSAVLCCRMAPLQKAQIVKLIKFSKEHPITLAIGDGANDVSMILEAHVGIGVIGKEGRQAARNSDYAIPKFKHLKKMLLVHGH
FYYIRISELVQYFFYKNVCFIFPQFLYQFFCGFSQQTLYDTAYLTLYNISFTSLPILLYSLMEQHVGIDVLKRDPTLYRDVAKNALLRWR
VFIYWTLLGLFDALVFFFGAYFVFENTTVTSNGQIFGNWTFGTLVFTVMVFTVTLKLALDTHYWTWINHFVIWGSLLFYVVFSLLWGGVI
WPFLNYQRMYYVFIQMLSSGPAWLAIVLLVTISLLPDVLKKVLCRQLWPTATERVQNGCAQPRDRDSEFTPLASLQSPGYQSTCPSAAWY

--------------------------------------------------------------
>6340_6340_3_ARHGEF7-ATP11A_ARHGEF7_chr13_111920017_ENST00000544132_ATP11A_chr13_113459271_ENST00000375645_length(transcript)=9452nt_BP=907nt
GAGATTGGTGCAGCCCCGGAGGAAGAAAAAAGGGTCTACCCCGAGCCCCGGAGCGAGAGCGAGTGCCTGAGCAACATCCGCGAGTTCCTG
CGCGGCTGCGGGGCTTCCCTGCGGCTGGAGACGTTTGATGCAAATGATTTGTATCAGGGGCAGAATTTTAACAAGGTCCTCAGTTCCTTA
GTGACTCTAAATAAAGTAACAGCAGGACATGACCGATAATAGCAACAATCAACTGGTAGTAAGAGCAAAGTTTAACTTCCAGCAGACCAA
TGAGGACGAGCTTTCCTTCTCAAAAGGAGACGTCATCCATGTCACCCGTGTGGAAGAGGGAGGCTGGTGGGAGGGCACACTCAACGGCCG
GACCGGCTGGTTCCCCAGCAACTACGTGCGCGAGGTCAAGGCCAGCGAGAAGCCTGTGTCTCCCAAATCAGGAACACTGAAGAGCCCTCC
CAAAGGATTTGATACGACTGCCATAAACAAAAGCTATTACAATGTGCCAGTACTTAGCCGCGGAGCGGAAAGCAGTGCTCATGAAGGTGG
AGGCACACCCAGAGACTGCATGGAGGTGGAACCGGGAAGTCCGGGGTCTGAGGTCCTGCCTGCAGGGTTGAAAGGCATGCCTGCCAGCAG
ACACATTTGGGAGCCAGAGTGTGCTGTGGTCTGAATGTGTTTCCCCAGATCATCTGTTACTACAGATGATCACCAATTGGATGGTATTAA
AAGCACACGTGCCCCTGCTCCGGGTTGTTGCTGTTGTCCTTCAGAAACTCTGAGGTCTGGAGAGGTTGCCCGAAGCTCAGCAGAGAGTCG
GAGGCTGCTTTTTAAACCTGATGCCACAGATGAAAACCCTGTACCTCACGTATTGTGCCAATCACCCTTCTGCAGTGAATGTCCTCACGG
AACACAGTACACATTTTGGAACTTTATACCCAAGAATTTATTTGAACAATTCAGAAGAGTAGCCAACTTTTATTTCCTTATCATATTTCT
GGTGCAGTTGATTATTGATACACCCACAAGTCCAGTGACAAGCGGACTTCCACTCTTCTTTGTCATTACTGTGACGGCTATCAAACAGGG
TTATGAAGACTGGCTTCGACATAAAGCAGACAATGCCATGAACCAGTGTCCTGTTCATTTCATTCAGCACGGCAAGCTCGTTCGGAAACA
AAGTCGAAAGCTGCGAGTTGGGGACATTGTCATGGTTAAGGAGGACGAGACCTTTCCCTGCGACTTGATCTTCCTTTCCAGCAACCGGGG
AGATGGGACGTGCCACGTCACCACCGCCAGCTTGGATGGAGAATCCAGCCATAAAACGCATTACGCGGTCCAGGACACCAAAGGCTTCCA
CACAGAGGAGGATATCGGCGGACTTCACGCCACCATCGAGTGTGAGCAGCCCCAGCCCGACCTCTACAAGTTCGTGGGTCGCATCAACGT
TTACAGTGACCTGAATGACCCCGTGGTGAGGCCCTTAGGATCGGAAAACCTGCTGCTTAGAGGAGCTACACTGAAGAACACTGAGAAAAT
CTTTGGTGTGGCTATTTACACGGGAATGGAAACCAAGATGGCATTAAATTATCAATCAAAATCTCAGAAGCGATCTGCCGTGGAAAAATC
GATGAATGCGTTCCTCATTGTGTATCTCTGCATTCTGATCAGCAAAGCCCTGATAAACACTGTGCTGAAATACATGTGGCAGAGTGAGCC
CTTTCGGGATGAGCCGTGGTATAATCAGAAAACGGAGTCGGAAAGGCAGAGGAATCTGTTCCTCAAGGCATTCACGGACTTCCTGGCCTT
CATGGTCCTCTTTAACTACATCATCCCTGTGTCCATGTACGTCACGGTCGAGATGCAGAAGTTCCTCGGCTCTTACTTCATCACCTGGGA
CGAAGACATGTTTGACGAGGAGACTGGCGAGGGGCCTCTGGTGAACACGTCGGACCTCAATGAAGAGCTGGGACAGGTGGAGTACATCTT
CACAGACAAGACCGGCACCCTCACGGAAAACAACATGGAGTTCAAGGAGTGCTGCATCGAAGGCCATGTCTACGTGCCCCACGTCATCTG
CAACGGGCAGGTCCTCCCAGAGTCGTCAGGAATCGACATGATTGACTCGTCCCCCAGCGTCAACGGGAGGGAGCGCGAGGAGCTGTTTTT
CCGGGCCCTCTGTCTCTGCCACACCGTCCAGGTGAAAGACGATGACAGCGTAGACGGCCCCAGGAAATCGCCGGACGGGGGGAAATCCTG
TGTGTACATCTCATCCTCGCCCGACGAGGTGGCGCTGGTCGAAGGTGTCCAGAGACTTGGCTTTACCTACCTAAGGCTGAAGGACAATTA
CATGGAGATATTAAACAGGGAGAACCACATCGAAAGGTTTGAATTGCTGGAAATTTTGAGTTTTGACTCAGTCAGAAGGAGAATGAGTGT
AATTGTAAAATCTGCTACAGGAGAAATTTATCTGTTTTGCAAAGGAGCAGATTCTTCGATATTCCCCCGAGTGATAGAAGGCAAAGTTGA
CCAGATCCGAGCCAGAGTGGAGCGTAACGCAGTGGAGGGGCTCCGAACTTTGTGTGTTGCTTATAAAAGGCTGATCCAAGAAGAATATGA
AGGCATTTGTAAGCTGCTGCAGGCTGCCAAAGTGGCCCTTCAAGATCGAGAGAAAAAGTTAGCAGAAGCCTATGAGCAAATAGAGAAAGA
TCTTACTCTGCTTGGTGCTACAGCTGTTGAGGACCGGCTGCAGGAGAAAGCTGCAGACACCATCGAGGCCCTGCAGAAGGCCGGGATCAA
AGTCTGGGTTCTCACGGGAGACAAGATGGAGACGGCCGCGGCCACGTGCTACGCCTGCAAGCTCTTCCGCAGGAACACGCAGCTGCTGGA
GCTGACCACCAAGAGGATCGAGGAGCAGAGCCTGCACGACGTCCTGTTCGAGCTGAGCAAGACGGTCCTGCGCCACAGCGGGAGCCTGAC
CAGAGACAACCTGTCCGGACTTTCAGCAGATATGCAGGACTACGGTTTAATTATCGACGGAGCTGCACTGTCTCTGATAATGAAGCCTCG
AGAAGACGGGAGTTCCGGCAACTACAGGGAGCTCTTCCTGGAAATCTGCCGGAGCTGCAGCGCGGTGCTCTGCTGCCGCATGGCGCCCTT
GCAGAAGGCTCAGATTGTTAAATTAATCAAATTTTCAAAAGAGCACCCAATCACGTTAGCAATTGGCGATGGTGCAAATGATGTCAGCAT
GATTCTGGAAGCGCACGTGGGCATAGGTGTCATCGGCAAGGAAGGCCGCCAGGCTGCCAGGAACAGCGACTATGCAATCCCAAAGTTTAA
GCATTTGAAGAAGATGCTGCTTGTTCACGGGCATTTTTATTACATTAGGATCTCTGAGCTCGTGCAGTACTTCTTCTATAAGAACGTCTG
CTTCATCTTCCCTCAGTTTTTATACCAGTTCTTCTGTGGGTTTTCACAACAGACTTTGTACGACACCGCGTATCTGACCCTCTACAACAT
CAGCTTCACCTCCCTCCCCATCCTCCTGTACAGCCTCATGGAGCAGCATGTTGGCATTGACGTGCTCAAGAGAGACCCGACCCTGTACAG
GGACGTCGCCAAGAATGCCCTGCTGCGCTGGCGCGTGTTCATCTACTGGACGCTCCTGGGACTGTTTGACGCACTGGTGTTCTTCTTTGG
TGCTTATTTCGTGTTTGAAAATACAACTGTGACAAGCAACGGGCAGATATTTGGAAACTGGACGTTTGGAACGCTGGTATTCACCGTGAT
GGTGTTCACAGTTACACTAAAGCTTGCATTGGACACACACTACTGGACTTGGATCAACCATTTTGTCATCTGGGGGTCGCTGCTGTTCTA
CGTTGTCTTTTCGCTTCTCTGGGGAGGAGTGATCTGGCCGTTCCTCAACTACCAGAGGATGTACTACGTGTTCATCCAGATGCTGTCCAG
CGGGCCCGCCTGGCTGGCCATCGTGCTGCTGGTGACCATCAGCCTCCTTCCCGACGTCCTCAAGAAAGTCCTGTGCCGGCAGCTGTGGCC
AACAGCAACAGAGAGAGTCCAGACTAAGAGCCAGTGCCTTTCTGTCGAGCAGTCAACCATCTTTATGCTTTCTCAGACTTCCAGCAGCCT
GAGTTTCTGATGGAACAAGAGCCCAGGCTACCAGAGCACCTGTCCCTCGGCCGCCTGGTACAGCTCCCACTCTCAGCAGGTGACACTCGC
GGCCTGGAAGGAGAAGGTGTCCACGGAGCCCCCACCCATCCTCGGCGGTTCCCATCACCACTGCAGTTCCATCCCAAGTCACAGCTGCCC
TAGGTCCCGTGTGGGAATGCTCGTGTGATGGATGGTCCTAAGCCTGTGGAGACTGTGCACGTGCCTCTTCCTGGCCCCCAGCAGGCAAGG
AGGGGGGTCACAGGCCTTGCCCTCGAGCATGGCACCCTGGCCGCCTGGACCCAGCACTGTGGTTGTTGAGCCACACCAGTGGCCTCTGGG
CATTCGGCTCAACGCAGGAGGGACATTCTGCTGGCCCACCCTGCGCGCTGTCATGCAGAGGCCATTCCCCCAGGCCTGTGTCTTCACCCA
CCTGCCATCATTGGCCTTTGCTGTCACTGGGAGAGAAGAGCCGTCCAGGGACCCATGGTGGCCCACATGTGGATGCCACATGCTGCTGTT
TCCTGCTTGCCCGGCCACCACCCATGCCCTCCATAGGGTGAGGTGGAGCCATGGTGGTGCGTCCTTTACTCAACAACCCTCCAATCCGGA
TGCTGTGGGAAGGGCCGGGTCACTCGGATACCATCATCCCTGCGGATGCACCGCCGTACCCTGCTCATCTGGGAGTGGTTTCCCTGCGGT
TACGTCCAAGCCCGCCTGCCCTGTGTGTTGGGGCTGGCTGAGTTTCGGTCTCCCCATCACCGGCCGCCTCGTGGAGAAGGCAGTGCCACG
TGGGAGGACAAGGCCACGCCGGCAGCTTCCAGCCCTGCCGCAGAAGTGCCAGGATGTCCATCAGCCACTCGCCAGGGCACGGAGCCGTCA
GTCCACTGTTACGGGAGAATGTTGATTTCGCGGGTGCGAGGGCCGGGAGACAGATACTTGGCTGTGATGAGCAGACATCCTCTGTCCCCG
TGGAGGGGTCAACACCAAGGTGGTGTTCGTGCACCAGAACCTGTCTCGGGCTGACGGGGGTGGCACACAGGACACGGGTGGATCCCAACA
GGCAGCACCGCACCTCTGCCCGCCTCCCGCACTGCAGCTCCGCCCGCCGGGCTCTGCGTCCCCACGTCCCCTCGTCCCATCCCCACGTCC
CCTCATCCCGTCACCTCGTCCCCACATCCCCTTGCCCCGTCACCTCGTCCTCATGTCCCCTTGTCCTGTCACCTCGTCCCCACGTCCCCT
CGTCTCCTCATCCCCACGTCCTCTCGTCCCCTTGTCCCGTCCCCACATACCCTCGTCCCCATGTCCCCACGCAGGGCTCTCCTTCGTCTT
AGGATCTGTCCAGCGCTGCTCTGGGTGGGTTAGCAACCCCAGGGCTGCTGTGATAGGAAGTCCCTGTTGTTCTCCGTACTGGCATTTCTA
TTTCTAGAAATAATATTTGACATAGCCTTAATGGTCCTTAAAGAAGACATTTCAGTGTGAGATTCAGACTTCAGACGCTGAAACTGCTGC
CTTTCAGGAAAGCACCACCAACGCTGGAGGAGGAGCCGGCCCTCACGCCCGCCCCGCGCCACGCTGTGGAACGGGGCTCCGGCAAGTGAA
ACCCAGAGGGTGTTTCCGAGGTGCTCGACAGTAGGTATTTTTGGAAGCTCAGATTTCACCATTTGATTGTATAATCTTTTACCTATAAAA
TATTTATTTGAAGTAGAGGGTAAATCAGCGGTAAGAACAGTGAACACAGTGGTTGGGATAAAATAAGGTGACAAACATCACACCAAAGAT
GAGGGTAGCGAGCAACTGGCTTGAGCAGACAGAACGGGGAAGACTCCACTCTGTCCCGAGGGGCCAGCCGCAGGCGTCCCCAGGGCCACC
CTGCCCTGAGGTCCTTGTGTGGCCGCCCTGGCTTGGCAGCCCTGCCCACGCTGCCCCCGCAAACAATGGTGTGTGCGTTTTTACAGCCCT
TTTTAGGAACCCAATATGGGCATAAATGTAACACCTGTAGCGGGGGCAGATTCTCTGTATGTTCAGTTAACAAATTATTTGTAATGTATT
TTTTTAGAAATCTTAAAATTGCCTTTGCACTGAAGTATTTTCATAGCTGTTTATATCTCTTTTATTCATTTATTTAACATACTGTCTAAT
TTTAAAAATAGGTTTTTAAAGCTTTCATTTTTAAGTTTATGAAATTTTGGCCACTTTACATTTAGATTCTGGTGAGAGTTTTGACTGAAT
GTTCCAATCTCTGATGAATGCGAATTTTCAGATTTGATTTTATTCTCTACACACACCTCTTCTTTTCTTGGTATTTCTGGTGGCAGTGAT
TAGTTGAACAGCACATTTAAGGCACGATAATTTGCTACACTTTTTCTTTACAATTTGTTGCAATTTCATCTGCTTTCTATGTTTCATTGT
TAATTGCCATCCTTCAGCCTTAAAAATAGAAGATTCTCACGTGAAGGTTTAGTAAGTTGGGTCCCAGCTCTGCCTGTGTGGAGATAGTCA
CCATGTACCTCTGACAACAAGTTTTAGTGTGAAAGTCACTAAACTTTTACACACTCCCAAACGTCTTTTTAAAAATTGCTTGGGAAATTA
TTAAATGAATGTGCCTGATGATTTGAAATAGACAAGGGGCACGAGATAAAAAAGAAAAGGATGAGAAGATCCTCAGTGAATGACGTTGCA
GGGTCTTCATGCAATTTTCCACCTCGCAGTAGTTAGTATTTACTTGCCTTAAACTAACTTTGAAGCAAGTAATGTCAACTTTGAGCACTT
TGTTGAGTTTTGAAAAATCTTATTTGTTGCTGCACAGGTTAATAAATTATCAATTTGTAATTCAGCATGTTGGTCAGAGACACGGTCACT
GATTCACACCCAGTCCCTGCCACAGACCGTCTCAGACACGCACAGTGGGCCTGCTGCATGATTCACACCCAGTCCCTGCCACAGACCGTC
TCAGACACGCACAGTGGGCCTGCTGCATGATTCACACCCAGTCCCTGCCACAGACCGTCTCAGACACGCACAGTGGGCCTGCTGCATGCG
TGTTACCTGGCTTTTGGCTCCACGCTCACTCATAGCCATGTCCACATGGGGGCTTGCACACAGGATCACTCACATATGTACATGTACCCA
CCACAAACGTGCAAGCTCCTGCACACATGCATGCACACAAACGTGTACACAAGTGTGAGCTCCTACACGCATACACACACACACGTGTAC
ATGCACCAAAGCATGTGTGACCTACAGACATGCAGAACATGCACGTGTACACATACCACAGACACGCGTGTGCATGCTCCTACACAATAC
ATATGCACATATCATGAACAGCGTAAGTTCCTACACACGGACGTGTGATACACACATGCATGTACAGGTAAGCACACATGTACAAGCTCC
TACAGGCTTGCTCTCACACACGTGTATGCACAGCAGAGAGACGTATGAGCTTCTACTGCACACATGCACACACACACGCACACGTACATT
CACTACAAACGTGCAGCCTCCTGCACACGTGCACATTCATGTGTACACCACAAATGAGTTCCCAGACGTGTAAACACACGTGCACACATC
GTACACATGTGAGCTCCCACACGTACACACAGATGCACATGGACACACCCCAAACACGCACAGGCTCCTACACACATGCACACACGTGTA
CACCACAAACGAGCTCCCAGACATGTAAACACACGTCTCCCACACGTGAGCTCCCACACGTACACATGCACATGTACGCACCACAAACAC
ATGCGCAGGCTCCTGCAGGCGTGAATACACACATGCACACACATATACACACATGTGCCACAAACAAGTGCACACTGTCCTGGTGTCCTG
CACTGCATCCTGCCTCCTTGCTGAGGGGCCCCTGTGAGAGGCCTCTGGATGGGCATGGGAAGATGGGCTCCCTGGCCCCCAGCCCATGCC
TCCCTGGGATGAAGAGTCCCCCTCCTGGCAGAATGTCTGGGCTTTGCAGAGCAGGCCCCGGGGGTGAAGTCGCAGCTTCACTTACACCAG
CTGCTCTGTGAGCAAGGCTTGGTGCCCTGGACAAGGCCCTTCCCCTTTAGGGAGGTCCAGCCTCGCAAGCTGAAACCTCCCCTCGGCTCA
GCCCTATACCAGGCGGCCACAGCAGGACTGGCCACACCCACGCCGCACCTCATCCGTGCACGCGTCGGAGCACGGCCAGCCTTCCGCCAC
GAGCCAGCTGGGAAGGGCCGCGGCCGCCTAAAGCCCCAGTCAACCCAGCCTGTGTCTGAGCAGACAGGGCGAACAAGCAGGCCACACCGT
CTCGAGGGAGGAGGCCAGATGCGGCCAGCGTCTCCAACAGGGTGACCATCCGCTCGGCTTGCTGAGCGTTTAAACAAATGTTTAGACAGG
CTGTGGGGACTCCCCTGAGTTGAGCCTTGGCCAGGGGTCCGGTGCTGTCGCGGGAAACCTCCAGCCTTGTTCTTCAAACCACTCAGCTCA
TGTGTTTTGCACTGACTAGTACTGAATAATACAACCACTCTTATTTAATGTTAGTATTATTTATTTGACAACTCAGTGTCTAACAGCTTG
ATATGCAGGTCCTTGCATCCTACATTTCTTTAGGAAGTTACCCATTTGTAACTTTAAAAACAGGAAAAATATCAGTTGGCAAATGCAATC
TTTTTTTTTTTTAAGCTAAAGGTGGGTGAACTGGAATGAAAATCTTTCTGATGTTGTGTCTATAAGCAGCCTTGATGGGATATGTTAGAA
GTGTCATGAAAGTGTGATTCTACTTTTGCAGAAAAATCTAAAGATCAATTTATATAGCTTTATTTTTTACTTTATCAAAGTATACAGAAT
TTTAATATGCATATATTGTGTCTGACTTAAAATTATAATGTCTGCGTCACCATTTAAAATGTCTGTTCATTATGTAATGTAATAAAAGAA
GGTCTTCAAAAATGTATTTAACATGAATGGTATCCATAGTTGTCATCATCATAAATACTGGAGTTTATTTTTAAATTATTAAACATAGTA
GGTGCATTAACATAAATCAGTCTCCACACAGTAACATTTAACTGATAATTCATTAATCAGCTTTGAAAAATTAAATTGTTAATTAAACCA
ATCTAACATTTCAGTAAAGTTTATTTTGTATGCTTCTGTTTTTAACTTTTATTTCTGTAGATAAACTGACTGGATAATATTATATTGGAC
TTTTCTCTAGATTATCTAAGCAGGAGACCTGAATCTGCTTGCAATAAAGAATAAAAGTCTGCTTCAGTTTCTTTATAAAGAAACTCACAC

>6340_6340_3_ARHGEF7-ATP11A_ARHGEF7_chr13_111920017_ENST00000544132_ATP11A_chr13_113459271_ENST00000375645_length(amino acids)=1161AA_BP=80
MCFPRSSVTTDDHQLDGIKSTRAPAPGCCCCPSETLRSGEVARSSAESRRLLFKPDATDENPVPHVLCQSPFCSECPHGTQYTFWNFIPK
NLFEQFRRVANFYFLIIFLVQLIIDTPTSPVTSGLPLFFVITVTAIKQGYEDWLRHKADNAMNQCPVHFIQHGKLVRKQSRKLRVGDIVM
VKEDETFPCDLIFLSSNRGDGTCHVTTASLDGESSHKTHYAVQDTKGFHTEEDIGGLHATIECEQPQPDLYKFVGRINVYSDLNDPVVRP
LGSENLLLRGATLKNTEKIFGVAIYTGMETKMALNYQSKSQKRSAVEKSMNAFLIVYLCILISKALINTVLKYMWQSEPFRDEPWYNQKT
ESERQRNLFLKAFTDFLAFMVLFNYIIPVSMYVTVEMQKFLGSYFITWDEDMFDEETGEGPLVNTSDLNEELGQVEYIFTDKTGTLTENN
MEFKECCIEGHVYVPHVICNGQVLPESSGIDMIDSSPSVNGREREELFFRALCLCHTVQVKDDDSVDGPRKSPDGGKSCVYISSSPDEVA
LVEGVQRLGFTYLRLKDNYMEILNRENHIERFELLEILSFDSVRRRMSVIVKSATGEIYLFCKGADSSIFPRVIEGKVDQIRARVERNAV
EGLRTLCVAYKRLIQEEYEGICKLLQAAKVALQDREKKLAEAYEQIEKDLTLLGATAVEDRLQEKAADTIEALQKAGIKVWVLTGDKMET
AAATCYACKLFRRNTQLLELTTKRIEEQSLHDVLFELSKTVLRHSGSLTRDNLSGLSADMQDYGLIIDGAALSLIMKPREDGSSGNYREL
FLEICRSCSAVLCCRMAPLQKAQIVKLIKFSKEHPITLAIGDGANDVSMILEAHVGIGVIGKEGRQAARNSDYAIPKFKHLKKMLLVHGH
FYYIRISELVQYFFYKNVCFIFPQFLYQFFCGFSQQTLYDTAYLTLYNISFTSLPILLYSLMEQHVGIDVLKRDPTLYRDVAKNALLRWR
VFIYWTLLGLFDALVFFFGAYFVFENTTVTSNGQIFGNWTFGTLVFTVMVFTVTLKLALDTHYWTWINHFVIWGSLLFYVVFSLLWGGVI

--------------------------------------------------------------
>6340_6340_4_ARHGEF7-ATP11A_ARHGEF7_chr13_111920017_ENST00000544132_ATP11A_chr13_113459271_ENST00000487903_length(transcript)=9515nt_BP=907nt
GAGATTGGTGCAGCCCCGGAGGAAGAAAAAAGGGTCTACCCCGAGCCCCGGAGCGAGAGCGAGTGCCTGAGCAACATCCGCGAGTTCCTG
CGCGGCTGCGGGGCTTCCCTGCGGCTGGAGACGTTTGATGCAAATGATTTGTATCAGGGGCAGAATTTTAACAAGGTCCTCAGTTCCTTA
GTGACTCTAAATAAAGTAACAGCAGGACATGACCGATAATAGCAACAATCAACTGGTAGTAAGAGCAAAGTTTAACTTCCAGCAGACCAA
TGAGGACGAGCTTTCCTTCTCAAAAGGAGACGTCATCCATGTCACCCGTGTGGAAGAGGGAGGCTGGTGGGAGGGCACACTCAACGGCCG
GACCGGCTGGTTCCCCAGCAACTACGTGCGCGAGGTCAAGGCCAGCGAGAAGCCTGTGTCTCCCAAATCAGGAACACTGAAGAGCCCTCC
CAAAGGATTTGATACGACTGCCATAAACAAAAGCTATTACAATGTGCCAGTACTTAGCCGCGGAGCGGAAAGCAGTGCTCATGAAGGTGG
AGGCACACCCAGAGACTGCATGGAGGTGGAACCGGGAAGTCCGGGGTCTGAGGTCCTGCCTGCAGGGTTGAAAGGCATGCCTGCCAGCAG
ACACATTTGGGAGCCAGAGTGTGCTGTGGTCTGAATGTGTTTCCCCAGATCATCTGTTACTACAGATGATCACCAATTGGATGGTATTAA
AAGCACACGTGCCCCTGCTCCGGGTTGTTGCTGTTGTCCTTCAGAAACTCTGAGGTCTGGAGAGGTTGCCCGAAGCTCAGCAGAGAGTCG
GAGGCTGCTTTTTAAACCTGATGCCACAGATGAAAACCCTGTACCTCACGTATTGTGCCAATCACCCTTCTGCAGTGAATGTCCTCACGG
AACACAGTACACATTTTGGAACTTTATACCCAAGAATTTATTTGAACAATTCAGAAGAGTAGCCAACTTTTATTTCCTTATCATATTTCT
GGTGCAGTTGATTATTGATACACCCACAAGTCCAGTGACAAGCGGACTTCCACTCTTCTTTGTCATTACTGTGACGGCTATCAAACAGGG
TTATGAAGACTGGCTTCGACATAAAGCAGACAATGCCATGAACCAGTGTCCTGTTCATTTCATTCAGCACGGCAAGCTCGTTCGGAAACA
AAGTCGAAAGCTGCGAGTTGGGGACATTGTCATGGTTAAGGAGGACGAGACCTTTCCCTGCGACTTGATCTTCCTTTCCAGCAACCGGGG
AGATGGGACGTGCCACGTCACCACCGCCAGCTTGGATGGAGAATCCAGCCATAAAACGCATTACGCGGTCCAGGACACCAAAGGCTTCCA
CACAGAGGAGGATATCGGCGGACTTCACGCCACCATCGAGTGTGAGCAGCCCCAGCCCGACCTCTACAAGTTCGTGGGTCGCATCAACGT
TTACAGTGACCTGAATGACCCCGTGGTGAGGCCCTTAGGATCGGAAAACCTGCTGCTTAGAGGAGCTACACTGAAGAACACTGAGAAAAT
CTTTGGTGTGGCTATTTACACGGGAATGGAAACCAAGATGGCATTAAATTATCAATCAAAATCTCAGAAGCGATCTGCCGTGGAAAAATC
GATGAATGCGTTCCTCATTGTGTATCTCTGCATTCTGATCAGCAAAGCCCTGATAAACACTGTGCTGAAATACATGTGGCAGAGTGAGCC
CTTTCGGGATGAGCCGTGGTATAATCAGAAAACGGAGTCGGAAAGGCAGAGGAATCTGTTCCTCAAGGCATTCACGGACTTCCTGGCCTT
CATGGTCCTCTTTAACTACATCATCCCTGTGTCCATGTACGTCACGGTCGAGATGCAGAAGTTCCTCGGCTCTTACTTCATCACCTGGGA
CGAAGACATGTTTGACGAGGAGACTGGCGAGGGGCCTCTGGTGAACACGTCGGACCTCAATGAAGAGCTGGGACAGGTGGAGTACATCTT
CACAGACAAGACCGGCACCCTCACGGAAAACAACATGGAGTTCAAGGAGTGCTGCATCGAAGGCCATGTCTACGTGCCCCACGTCATCTG
CAACGGGCAGGTCCTCCCAGAGTCGTCAGGAATCGACATGATTGACTCGTCCCCCAGCGTCAACGGGAGGGAGCGCGAGGAGCTGTTTTT
CCGGGCCCTCTGTCTCTGCCACACCGTCCAGGTGAAAGACGATGACAGCGTAGACGGCCCCAGGAAATCGCCGGACGGGGGGAAATCCTG
TGTGTACATCTCATCCTCGCCCGACGAGGTGGCGCTGGTCGAAGGTGTCCAGAGACTTGGCTTTACCTACCTAAGGCTGAAGGACAATTA
CATGGAGATATTAAACAGGGAGAACCACATCGAAAGGTTTGAATTGCTGGAAATTTTGAGTTTTGACTCAGTCAGAAGGAGAATGAGTGT
AATTGTAAAATCTGCTACAGGAGAAATTTATCTGTTTTGCAAAGGAGCAGATTCTTCGATATTCCCCCGAGTGATAGAAGGCAAAGTTGA
CCAGATCCGAGCCAGAGTGGAGCGTAACGCAGTGGAGGGGCTCCGAACTTTGTGTGTTGCTTATAAAAGGCTGATCCAAGAAGAATATGA
AGGCATTTGTAAGCTGCTGCAGGCTGCCAAAGTGGCCCTTCAAGATCGAGAGAAAAAGTTAGCAGAAGCCTATGAGCAAATAGAGAAAGA
TCTTACTCTGCTTGGTGCTACAGCTGTTGAGGACCGGCTGCAGGAGAAAGCTGCAGACACCATCGAGGCCCTGCAGAAGGCCGGGATCAA
AGTCTGGGTTCTCACGGGAGACAAGATGGAGACGGCCGCGGCCACGTGCTACGCCTGCAAGCTCTTCCGCAGGAACACGCAGCTGCTGGA
GCTGACCACCAAGAGGATCGAGGAGCAGAGCCTGCACGACGTCCTGTTCGAGCTGAGCAAGACGGTCCTGCGCCACAGCGGGAGCCTGAC
CAGAGACAACCTGTCCGGACTTTCAGCAGATATGCAGGACTACGGTTTAATTATCGACGGAGCTGCACTGTCTCTGATAATGAAGCCTCG
AGAAGACGGGAGTTCCGGCAACTACAGGGAGCTCTTCCTGGAAATCTGCCGGAGCTGCAGCGCGGTGCTCTGCTGCCGCATGGCGCCCTT
GCAGAAGGCTCAGATTGTTAAATTAATCAAATTTTCAAAAGAGCACCCAATCACGTTAGCAATTGGCGATGGTGCAAATGATGTCAGCAT
GATTCTGGAAGCGCACGTGGGCATAGGTGTCATCGGCAAGGAAGGCCGCCAGGCTGCCAGGAACAGCGACTATGCAATCCCAAAGTTTAA
GCATTTGAAGAAGATGCTGCTTGTTCACGGGCATTTTTATTACATTAGGATCTCTGAGCTCGTGCAGTACTTCTTCTATAAGAACGTCTG
CTTCATCTTCCCTCAGTTTTTATACCAGTTCTTCTGTGGGTTTTCACAACAGACTTTGTACGACACCGCGTATCTGACCCTCTACAACAT
CAGCTTCACCTCCCTCCCCATCCTCCTGTACAGCCTCATGGAGCAGCATGTTGGCATTGACGTGCTCAAGAGAGACCCGACCCTGTACAG
GGACGTCGCCAAGAATGCCCTGCTGCGCTGGCGCGTGTTCATCTACTGGACGCTCCTGGGACTGTTTGACGCACTGGTGTTCTTCTTTGG
TGCTTATTTCGTGTTTGAAAATACAACTGTGACAAGCAACGGGCAGATATTTGGAAACTGGACGTTTGGAACGCTGGTATTCACCGTGAT
GGTGTTCACAGTTACACTAAAGCTTGCATTGGACACACACTACTGGACTTGGATCAACCATTTTGTCATCTGGGGGTCGCTGCTGTTCTA
CGTTGTCTTTTCGCTTCTCTGGGGAGGAGTGATCTGGCCGTTCCTCAACTACCAGAGGATGTACTACGTGTTCATCCAGATGCTGTCCAG
CGGGCCCGCCTGGCTGGCCATCGTGCTGCTGGTGACCATCAGCCTCCTTCCCGACGTCCTCAAGAAAGTCCTGTGCCGGCAGCTGTGGCC
AACAGCAACAGAGAGAGTCCAGACTAAGAGCCAGTGCCTTTCTGTCGAGCAGTCAACCATCTTTATGCTTTCTCAGACTTCCAGCAGCCT
GAGTTTCTGATGGAACAAGCAGAATGGGTGCGCACAGCCTCGGGACCGCGACTCAGAATTCACCCCTCTTGCCTCTCTGCAGAGCCCAGG
CTACCAGAGCACCTGTCCCTCGGCCGCCTGGTACAGCTCCCACTCTCAGCAGGTGACACTCGCGGCCTGGAAGGAGAAGGTGTCCACGGA
GCCCCCACCCATCCTCGGCGGTTCCCATCACCACTGCAGTTCCATCCCAAGTCACAGCTGCCCTAGGTCCCGTGTGGGAATGCTCGTGTG
ATGGATGGTCCTAAGCCTGTGGAGACTGTGCACGTGCCTCTTCCTGGCCCCCAGCAGGCAAGGAGGGGGGTCACAGGCCTTGCCCTCGAG
CATGGCACCCTGGCCGCCTGGACCCAGCACTGTGGTTGTTGAGCCACACCAGTGGCCTCTGGGCATTCGGCTCAACGCAGGAGGGACATT
CTGCTGGCCCACCCTGCGCGCTGTCATGCAGAGGCCATTCCCCCAGGCCTGTGTCTTCACCCACCTGCCATCATTGGCCTTTGCTGTCAC
TGGGAGAGAAGAGCCGTCCAGGGACCCATGGTGGCCCACATGTGGATGCCACATGCTGCTGTTTCCTGCTTGCCCGGCCACCACCCATGC
CCTCCATAGGGTGAGGTGGAGCCATGGTGGTGCGTCCTTTACTCAACAACCCTCCAATCCGGATGCTGTGGGAAGGGCCGGGTCACTCGG
ATACCATCATCCCTGCGGATGCACCGCCGTACCCTGCTCATCTGGGAGTGGTTTCCCTGCGGTTACGTCCAAGCCCGCCTGCCCTGTGTG
TTGGGGCTGGCTGAGTTTCGGTCTCCCCATCACCGGCCGCCTCGTGGAGAAGGCAGTGCCACGTGGGAGGACAAGGCCACGCCGGCAGCT
TCCAGCCCTGCCGCAGAAGTGCCAGGATGTCCATCAGCCACTCGCCAGGGCACGGAGCCGTCAGTCCACTGTTACGGGAGAATGTTGATT
TCGCGGGTGCGAGGGCCGGGAGACAGATACTTGGCTGTGATGAGCAGACATCCTCTGTCCCCGTGGAGGGGTCAACACCAAGGTGGTGTT
CGTGCACCAGAACCTGTCTCGGGCTGACGGGGGTGGCACACAGGACACGGGTGGATCCCAACAGGCAGCACCGCACCTCTGCCCGCCTCC
CGCACTGCAGCTCCGCCCGCCGGGCTCTGCGTCCCCACGTCCCCTCGTCCCATCCCCACGTCCCCTCATCCCGTCACCTCGTCCCCACAT
CCCCTTGCCCCGTCACCTCGTCCTCATGTCCCCTTGTCCTGTCACCTCGTCCCCACGTCCCCTCGTCTCCTCATCCCCACGTCCTCTCGT
CCCCTTGTCCCGTCCCCACATACCCTCGTCCCCATGTCCCCACGCAGGGCTCTCCTTCGTCTTAGGATCTGTCCAGCGCTGCTCTGGGTG
GGTTAGCAACCCCAGGGCTGCTGTGATAGGAAGTCCCTGTTGTTCTCCGTACTGGCATTTCTATTTCTAGAAATAATATTTGACATAGCC
TTAATGGTCCTTAAAGAAGACATTTCAGTGTGAGATTCAGACTTCAGACGCTGAAACTGCTGCCTTTCAGGAAAGCACCACCAACGCTGG
AGGAGGAGCCGGCCCTCACGCCCGCCCCGCGCCACGCTGTGGAACGGGGCTCCGGCAAGTGAAACCCAGAGGGTGTTTCCGAGGTGCTCG
ACAGTAGGTATTTTTGGAAGCTCAGATTTCACCATTTGATTGTATAATCTTTTACCTATAAAATATTTATTTGAAGTAGAGGGTAAATCA
GCGGTAAGAACAGTGAACACAGTGGTTGGGATAAAATAAGGTGACAAACATCACACCAAAGATGAGGGTAGCGAGCAACTGGCTTGAGCA
GACAGAACGGGGAAGACTCCACTCTGTCCCGAGGGGCCAGCCGCAGGCGTCCCCAGGGCCACCCTGCCCTGAGGTCCTTGTGTGGCCGCC
CTGGCTTGGCAGCCCTGCCCACGCTGCCCCCGCAAACAATGGTGTGTGCGTTTTTACAGCCCTTTTTAGGAACCCAATATGGGCATAAAT
GTAACACCTGTAGCGGGGGCAGATTCTCTGTATGTTCAGTTAACAAATTATTTGTAATGTATTTTTTTAGAAATCTTAAAATTGCCTTTG
CACTGAAGTATTTTCATAGCTGTTTATATCTCTTTTATTCATTTATTTAACATACTGTCTAATTTTAAAAATAGGTTTTTAAAGCTTTCA
TTTTTAAGTTTATGAAATTTTGGCCACTTTACATTTAGATTCTGGTGAGAGTTTTGACTGAATGTTCCAATCTCTGATGAATGCGAATTT
TCAGATTTGATTTTATTCTCTACACACACCTCTTCTTTTCTTGGTATTTCTGGTGGCAGTGATTAGTTGAACAGCACATTTAAGGCACGA
TAATTTGCTACACTTTTTCTTTACAATTTGTTGCAATTTCATCTGCTTTCTATGTTTCATTGTTAATTGCCATCCTTCAGCCTTAAAAAT
AGAAGATTCTCACGTGAAGGTTTAGTAAGTTGGGTCCCAGCTCTGCCTGTGTGGAGATAGTCACCATGTACCTCTGACAACAAGTTTTAG
TGTGAAAGTCACTAAACTTTTACACACTCCCAAACGTCTTTTTAAAAATTGCTTGGGAAATTATTAAATGAATGTGCCTGATGATTTGAA
ATAGACAAGGGGCACGAGATAAAAAAGAAAAGGATGAGAAGATCCTCAGTGAATGACGTTGCAGGGTCTTCATGCAATTTTCCACCTCGC
AGTAGTTAGTATTTACTTGCCTTAAACTAACTTTGAAGCAAGTAATGTCAACTTTGAGCACTTTGTTGAGTTTTGAAAAATCTTATTTGT
TGCTGCACAGGTTAATAAATTATCAATTTGTAATTCAGCATGTTGGTCAGAGACACGGTCACTGATTCACACCCAGTCCCTGCCACAGAC
CGTCTCAGACACGCACAGTGGGCCTGCTGCATGATTCACACCCAGTCCCTGCCACAGACCGTCTCAGACACGCACAGTGGGCCTGCTGCA
TGATTCACACCCAGTCCCTGCCACAGACCGTCTCAGACACGCACAGTGGGCCTGCTGCATGCGTGTTACCTGGCTTTTGGCTCCACGCTC
ACTCATAGCCATGTCCACATGGGGGCTTGCACACAGGATCACTCACATATGTACATGTACCCACCACAAACGTGCAAGCTCCTGCACACA
TGCATGCACACAAACGTGTACACAAGTGTGAGCTCCTACACGCATACACACACACACGTGTACATGCACCAAAGCATGTGTGACCTACAG
ACATGCAGAACATGCACGTGTACACATACCACAGACACGCGTGTGCATGCTCCTACACAATACATATGCACATATCATGAACAGCGTAAG
TTCCTACACACGGACGTGTGATACACACATGCATGTACAGGTAAGCACACATGTACAAGCTCCTACAGGCTTGCTCTCACACACGTGTAT
GCACAGCAGAGAGACGTATGAGCTTCTACTGCACACATGCACACACACACGCACACGTACATTCACTACAAACGTGCAGCCTCCTGCACA
CGTGCACATTCATGTGTACACCACAAATGAGTTCCCAGACGTGTAAACACACGTGCACACATCGTACACATGTGAGCTCCCACACGTACA
CACAGATGCACATGGACACACCCCAAACACGCACAGGCTCCTACACACATGCACACACGTGTACACCACAAACGAGCTCCCAGACATGTA
AACACACGTCTCCCACACGTGAGCTCCCACACGTACACATGCACATGTACGCACCACAAACACATGCGCAGGCTCCTGCAGGCGTGAATA
CACACATGCACACACATATACACACATGTGCCACAAACAAGTGCACACTGTCCTGGTGTCCTGCACTGCATCCTGCCTCCTTGCTGAGGG
GCCCCTGTGAGAGGCCTCTGGATGGGCATGGGAAGATGGGCTCCCTGGCCCCCAGCCCATGCCTCCCTGGGATGAAGAGTCCCCCTCCTG
GCAGAATGTCTGGGCTTTGCAGAGCAGGCCCCGGGGGTGAAGTCGCAGCTTCACTTACACCAGCTGCTCTGTGAGCAAGGCTTGGTGCCC
TGGACAAGGCCCTTCCCCTTTAGGGAGGTCCAGCCTCGCAAGCTGAAACCTCCCCTCGGCTCAGCCCTATACCAGGCGGCCACAGCAGGA
CTGGCCACACCCACGCCGCACCTCATCCGTGCACGCGTCGGAGCACGGCCAGCCTTCCGCCACGAGCCAGCTGGGAAGGGCCGCGGCCGC
CTAAAGCCCCAGTCAACCCAGCCTGTGTCTGAGCAGACAGGGCGAACAAGCAGGCCACACCGTCTCGAGGGAGGAGGCCAGATGCGGCCA
GCGTCTCCAACAGGGTGACCATCCGCTCGGCTTGCTGAGCGTTTAAACAAATGTTTAGACAGGCTGTGGGGACTCCCCTGAGTTGAGCCT
TGGCCAGGGGTCCGGTGCTGTCGCGGGAAACCTCCAGCCTTGTTCTTCAAACCACTCAGCTCATGTGTTTTGCACTGACTAGTACTGAAT
AATACAACCACTCTTATTTAATGTTAGTATTATTTATTTGACAACTCAGTGTCTAACAGCTTGATATGCAGGTCCTTGCATCCTACATTT
CTTTAGGAAGTTACCCATTTGTAACTTTAAAAACAGGAAAAATATCAGTTGGCAAATGCAATCTTTTTTTTTTTTAAGCTAAAGGTGGGT
GAACTGGAATGAAAATCTTTCTGATGTTGTGTCTATAAGCAGCCTTGATGGGATATGTTAGAAGTGTCATGAAAGTGTGATTCTACTTTT
GCAGAAAAATCTAAAGATCAATTTATATAGCTTTATTTTTTACTTTATCAAAGTATACAGAATTTTAATATGCATATATTGTGTCTGACT
TAAAATTATAATGTCTGCGTCACCATTTAAAATGTCTGTTCATTATGTAATGTAATAAAAGAAGGTCTTCAAAAATGTATTTAACATGAA
TGGTATCCATAGTTGTCATCATCATAAATACTGGAGTTTATTTTTAAATTATTAAACATAGTAGGTGCATTAACATAAATCAGTCTCCAC
ACAGTAACATTTAACTGATAATTCATTAATCAGCTTTGAAAAATTAAATTGTTAATTAAACCAATCTAACATTTCAGTAAAGTTTATTTT
GTATGCTTCTGTTTTTAACTTTTATTTCTGTAGATAAACTGACTGGATAATATTATATTGGACTTTTCTCTAGATTATCTAAGCAGGAGA

>6340_6340_4_ARHGEF7-ATP11A_ARHGEF7_chr13_111920017_ENST00000544132_ATP11A_chr13_113459271_ENST00000487903_length(amino acids)=1161AA_BP=80
MCFPRSSVTTDDHQLDGIKSTRAPAPGCCCCPSETLRSGEVARSSAESRRLLFKPDATDENPVPHVLCQSPFCSECPHGTQYTFWNFIPK
NLFEQFRRVANFYFLIIFLVQLIIDTPTSPVTSGLPLFFVITVTAIKQGYEDWLRHKADNAMNQCPVHFIQHGKLVRKQSRKLRVGDIVM
VKEDETFPCDLIFLSSNRGDGTCHVTTASLDGESSHKTHYAVQDTKGFHTEEDIGGLHATIECEQPQPDLYKFVGRINVYSDLNDPVVRP
LGSENLLLRGATLKNTEKIFGVAIYTGMETKMALNYQSKSQKRSAVEKSMNAFLIVYLCILISKALINTVLKYMWQSEPFRDEPWYNQKT
ESERQRNLFLKAFTDFLAFMVLFNYIIPVSMYVTVEMQKFLGSYFITWDEDMFDEETGEGPLVNTSDLNEELGQVEYIFTDKTGTLTENN
MEFKECCIEGHVYVPHVICNGQVLPESSGIDMIDSSPSVNGREREELFFRALCLCHTVQVKDDDSVDGPRKSPDGGKSCVYISSSPDEVA
LVEGVQRLGFTYLRLKDNYMEILNRENHIERFELLEILSFDSVRRRMSVIVKSATGEIYLFCKGADSSIFPRVIEGKVDQIRARVERNAV
EGLRTLCVAYKRLIQEEYEGICKLLQAAKVALQDREKKLAEAYEQIEKDLTLLGATAVEDRLQEKAADTIEALQKAGIKVWVLTGDKMET
AAATCYACKLFRRNTQLLELTTKRIEEQSLHDVLFELSKTVLRHSGSLTRDNLSGLSADMQDYGLIIDGAALSLIMKPREDGSSGNYREL
FLEICRSCSAVLCCRMAPLQKAQIVKLIKFSKEHPITLAIGDGANDVSMILEAHVGIGVIGKEGRQAARNSDYAIPKFKHLKKMLLVHGH
FYYIRISELVQYFFYKNVCFIFPQFLYQFFCGFSQQTLYDTAYLTLYNISFTSLPILLYSLMEQHVGIDVLKRDPTLYRDVAKNALLRWR
VFIYWTLLGLFDALVFFFGAYFVFENTTVTSNGQIFGNWTFGTLVFTVMVFTVTLKLALDTHYWTWINHFVIWGSLLFYVVFSLLWGGVI

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Fusion Gene PPI Analysis for ARHGEF7-ATP11A


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ARHGEF7-ATP11A


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ARHGEF7-ATP11A


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneC0085786Hamman-Rich syndrome1ORPHANET
TgeneC1800706Idiopathic Pulmonary Fibrosis1CTD_human;ORPHANET
TgeneC4721508Hamman-Rich Disease1CTD_human
TgeneC4721509Usual Interstitial Pneumonia1CTD_human
TgeneC4721952Familial Idiopathic Pulmonary Fibrosis1CTD_human