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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Fusion gene:AP3D1-KCTD19 (FusionGDB2 ID:HG8943TG146212)

Fusion Gene Summary for AP3D1-KCTD19

check button Fusion gene summary
Fusion gene informationFusion gene name: AP3D1-KCTD19
Fusion gene ID: hg8943tg146212
HgeneTgene
Gene symbol

AP3D1

KCTD19

Gene ID

8943

146212

Gene nameadaptor related protein complex 3 subunit delta 1potassium channel tetramerization domain containing 19
SynonymsADTD|HPS10|hBLVR-
Cytomap('AP3D1')('KCTD19')

19p13.3

16q22.1

Type of geneprotein-codingprotein-coding
DescriptionAP-3 complex subunit delta-1AP-3 complex delta subunit, partial CDSadapter-related protein complex 3 subunit delta-1adaptor related protein complex 3 delta 1 subunitdelta adaptinsubunit of putative vesicle coat adaptor complex AP-3BTB/POZ domain-containing protein KCTD19potassium channel tetramerisation domain containing 19testicular tissue protein Li 101
Modification date2020031320200313
UniProtAcc.

Q17RG1

Ensembl transtripts involved in fusion geneENST00000345016, ENST00000350812, 
ENST00000355272, ENST00000356926, 
ENST00000590683, 
Fusion gene scores* DoF score16 X 16 X 10=25605 X 3 X 4=60
# samples 194
** MAII scorelog2(19/2560*10)=-3.75207248655641
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(4/60*10)=-0.584962500721156
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: AP3D1 [Title/Abstract] AND KCTD19 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointAP3D1(2138618)-KCTD19(67354788), # samples:2
Anticipated loss of major functional domain due to fusion event.AP3D1-KCTD19 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
AP3D1-KCTD19 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
AP3D1-KCTD19 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
AP3D1-KCTD19 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across AP3D1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across KCTD19 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4PRADTCGA-VP-A875-01AAP3D1chr19

2137726

-KCTD19chr16

67354788

-
ChimerDB4PRADTCGA-VP-A875-01AAP3D1chr19

2138618

-KCTD19chr16

67354788

-
ChimerDB4PRADTCGA-VP-A875AP3D1chr19

2138618

-KCTD19chr16

67354788

-


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Fusion Gene ORF analysis for AP3D1-KCTD19

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000345016ENST00000562860AP3D1chr19

2137726

-KCTD19chr16

67354788

-
5CDS-intronENST00000345016ENST00000562860AP3D1chr19

2138618

-KCTD19chr16

67354788

-
5CDS-intronENST00000350812ENST00000562860AP3D1chr19

2137726

-KCTD19chr16

67354788

-
5CDS-intronENST00000350812ENST00000562860AP3D1chr19

2138618

-KCTD19chr16

67354788

-
5CDS-intronENST00000355272ENST00000562860AP3D1chr19

2137726

-KCTD19chr16

67354788

-
5CDS-intronENST00000355272ENST00000562860AP3D1chr19

2138618

-KCTD19chr16

67354788

-
5CDS-intronENST00000356926ENST00000562860AP3D1chr19

2137726

-KCTD19chr16

67354788

-
5CDS-intronENST00000356926ENST00000562860AP3D1chr19

2138618

-KCTD19chr16

67354788

-
In-frameENST00000345016ENST00000304372AP3D1chr19

2137726

-KCTD19chr16

67354788

-
In-frameENST00000345016ENST00000304372AP3D1chr19

2138618

-KCTD19chr16

67354788

-
In-frameENST00000350812ENST00000304372AP3D1chr19

2137726

-KCTD19chr16

67354788

-
In-frameENST00000350812ENST00000304372AP3D1chr19

2138618

-KCTD19chr16

67354788

-
In-frameENST00000355272ENST00000304372AP3D1chr19

2137726

-KCTD19chr16

67354788

-
In-frameENST00000355272ENST00000304372AP3D1chr19

2138618

-KCTD19chr16

67354788

-
In-frameENST00000356926ENST00000304372AP3D1chr19

2137726

-KCTD19chr16

67354788

-
In-frameENST00000356926ENST00000304372AP3D1chr19

2138618

-KCTD19chr16

67354788

-
intron-3CDSENST00000590683ENST00000304372AP3D1chr19

2137726

-KCTD19chr16

67354788

-
intron-3CDSENST00000590683ENST00000304372AP3D1chr19

2138618

-KCTD19chr16

67354788

-
intron-intronENST00000590683ENST00000562860AP3D1chr19

2137726

-KCTD19chr16

67354788

-
intron-intronENST00000590683ENST00000562860AP3D1chr19

2138618

-KCTD19chr16

67354788

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000355272AP3D1chr192138618-ENST00000304372KCTD19chr1667354788-32983999031761028
ENST00000356926AP3D1chr192138618-ENST00000304372KCTD19chr1667354788-331441510631921028
ENST00000350812AP3D1chr192138618-ENST00000304372KCTD19chr1667354788-32973988931751028
ENST00000345016AP3D1chr192138618-ENST00000304372KCTD19chr1667354788-332342411532011028
ENST00000355272AP3D1chr192137726-ENST00000304372KCTD19chr1667354788-33794809032571055
ENST00000356926AP3D1chr192137726-ENST00000304372KCTD19chr1667354788-339549610632731055
ENST00000350812AP3D1chr192137726-ENST00000304372KCTD19chr1667354788-33784798932561055
ENST00000345016AP3D1chr192137726-ENST00000304372KCTD19chr1667354788-340450511532821055

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000355272ENST00000304372AP3D1chr192138618-KCTD19chr1667354788-0.0050574610.9949425
ENST00000356926ENST00000304372AP3D1chr192138618-KCTD19chr1667354788-0.0051875810.99481237
ENST00000350812ENST00000304372AP3D1chr192138618-KCTD19chr1667354788-0.0050735970.99492645
ENST00000345016ENST00000304372AP3D1chr192138618-KCTD19chr1667354788-0.0052535210.9947465
ENST00000355272ENST00000304372AP3D1chr192137726-KCTD19chr1667354788-0.0056789450.994321
ENST00000356926ENST00000304372AP3D1chr192137726-KCTD19chr1667354788-0.0058365090.99416345
ENST00000350812ENST00000304372AP3D1chr192137726-KCTD19chr1667354788-0.0056945070.99430543
ENST00000345016ENST00000304372AP3D1chr192137726-KCTD19chr1667354788-0.0059266310.99407333

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Fusion Genomic Features for AP3D1-KCTD19


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

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Fusion Protein Features for AP3D1-KCTD19


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr19:2138618/chr16:67354788)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.KCTD19

Q17RG1

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneAP3D1chr19:2137726chr16:67354788ENST00000345016-33034_71911154.0RepeatNote=HEAT 1
HgeneAP3D1chr19:2137726chr16:67354788ENST00000355272-33234_71911216.0RepeatNote=HEAT 1
TgeneKCTD19chr19:2137726chr16:67354788ENST0000030437201618_721927.0DomainNote=BTB 1
TgeneKCTD19chr19:2137726chr16:67354788ENST00000304372016398_4851927.0DomainNote=BTB 2
TgeneKCTD19chr19:2138618chr16:67354788ENST0000030437201618_721927.0DomainNote=BTB 1
TgeneKCTD19chr19:2138618chr16:67354788ENST00000304372016398_4851927.0DomainNote=BTB 2

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneAP3D1chr19:2137726chr16:67354788ENST00000345016-330659_679911154.0Coiled coilOntology_term=ECO:0000255
HgeneAP3D1chr19:2137726chr16:67354788ENST00000345016-330725_756911154.0Coiled coilOntology_term=ECO:0000255
HgeneAP3D1chr19:2137726chr16:67354788ENST00000345016-330845_869911154.0Coiled coilOntology_term=ECO:0000255
HgeneAP3D1chr19:2137726chr16:67354788ENST00000355272-332659_679911216.0Coiled coilOntology_term=ECO:0000255
HgeneAP3D1chr19:2137726chr16:67354788ENST00000355272-332725_756911216.0Coiled coilOntology_term=ECO:0000255
HgeneAP3D1chr19:2137726chr16:67354788ENST00000355272-332845_869911216.0Coiled coilOntology_term=ECO:0000255
HgeneAP3D1chr19:2138618chr16:67354788ENST00000345016-230659_679641154.0Coiled coilOntology_term=ECO:0000255
HgeneAP3D1chr19:2138618chr16:67354788ENST00000345016-230725_756641154.0Coiled coilOntology_term=ECO:0000255
HgeneAP3D1chr19:2138618chr16:67354788ENST00000345016-230845_869641154.0Coiled coilOntology_term=ECO:0000255
HgeneAP3D1chr19:2138618chr16:67354788ENST00000355272-232659_679641216.0Coiled coilOntology_term=ECO:0000255
HgeneAP3D1chr19:2138618chr16:67354788ENST00000355272-232725_756641216.0Coiled coilOntology_term=ECO:0000255
HgeneAP3D1chr19:2138618chr16:67354788ENST00000355272-232845_869641216.0Coiled coilOntology_term=ECO:0000255
HgeneAP3D1chr19:2137726chr16:67354788ENST00000345016-330828_893911154.0Compositional biasNote=Lys-rich
HgeneAP3D1chr19:2137726chr16:67354788ENST00000355272-332828_893911216.0Compositional biasNote=Lys-rich
HgeneAP3D1chr19:2138618chr16:67354788ENST00000345016-230828_893641154.0Compositional biasNote=Lys-rich
HgeneAP3D1chr19:2138618chr16:67354788ENST00000355272-232828_893641216.0Compositional biasNote=Lys-rich
HgeneAP3D1chr19:2137726chr16:67354788ENST00000345016-330142_179911154.0RepeatNote=HEAT 3
HgeneAP3D1chr19:2137726chr16:67354788ENST00000345016-330180_216911154.0RepeatNote=HEAT 4
HgeneAP3D1chr19:2137726chr16:67354788ENST00000345016-330254_292911154.0RepeatNote=HEAT 5
HgeneAP3D1chr19:2137726chr16:67354788ENST00000345016-330299_336911154.0RepeatNote=HEAT 6
HgeneAP3D1chr19:2137726chr16:67354788ENST00000345016-330338_373911154.0RepeatNote=HEAT 7
HgeneAP3D1chr19:2137726chr16:67354788ENST00000345016-330375_409911154.0RepeatNote=HEAT 8
HgeneAP3D1chr19:2137726chr16:67354788ENST00000345016-330431_468911154.0RepeatNote=HEAT 9
HgeneAP3D1chr19:2137726chr16:67354788ENST00000345016-330497_535911154.0RepeatNote=HEAT 10
HgeneAP3D1chr19:2137726chr16:67354788ENST00000345016-330548_585911154.0RepeatNote=HEAT 11
HgeneAP3D1chr19:2137726chr16:67354788ENST00000345016-33077_114911154.0RepeatNote=HEAT 2
HgeneAP3D1chr19:2137726chr16:67354788ENST00000355272-332142_179911216.0RepeatNote=HEAT 3
HgeneAP3D1chr19:2137726chr16:67354788ENST00000355272-332180_216911216.0RepeatNote=HEAT 4
HgeneAP3D1chr19:2137726chr16:67354788ENST00000355272-332254_292911216.0RepeatNote=HEAT 5
HgeneAP3D1chr19:2137726chr16:67354788ENST00000355272-332299_336911216.0RepeatNote=HEAT 6
HgeneAP3D1chr19:2137726chr16:67354788ENST00000355272-332338_373911216.0RepeatNote=HEAT 7
HgeneAP3D1chr19:2137726chr16:67354788ENST00000355272-332375_409911216.0RepeatNote=HEAT 8
HgeneAP3D1chr19:2137726chr16:67354788ENST00000355272-332431_468911216.0RepeatNote=HEAT 9
HgeneAP3D1chr19:2137726chr16:67354788ENST00000355272-332497_535911216.0RepeatNote=HEAT 10
HgeneAP3D1chr19:2137726chr16:67354788ENST00000355272-332548_585911216.0RepeatNote=HEAT 11
HgeneAP3D1chr19:2137726chr16:67354788ENST00000355272-33277_114911216.0RepeatNote=HEAT 2
HgeneAP3D1chr19:2138618chr16:67354788ENST00000345016-230142_179641154.0RepeatNote=HEAT 3
HgeneAP3D1chr19:2138618chr16:67354788ENST00000345016-230180_216641154.0RepeatNote=HEAT 4
HgeneAP3D1chr19:2138618chr16:67354788ENST00000345016-230254_292641154.0RepeatNote=HEAT 5
HgeneAP3D1chr19:2138618chr16:67354788ENST00000345016-230299_336641154.0RepeatNote=HEAT 6
HgeneAP3D1chr19:2138618chr16:67354788ENST00000345016-230338_373641154.0RepeatNote=HEAT 7
HgeneAP3D1chr19:2138618chr16:67354788ENST00000345016-23034_71641154.0RepeatNote=HEAT 1
HgeneAP3D1chr19:2138618chr16:67354788ENST00000345016-230375_409641154.0RepeatNote=HEAT 8
HgeneAP3D1chr19:2138618chr16:67354788ENST00000345016-230431_468641154.0RepeatNote=HEAT 9
HgeneAP3D1chr19:2138618chr16:67354788ENST00000345016-230497_535641154.0RepeatNote=HEAT 10
HgeneAP3D1chr19:2138618chr16:67354788ENST00000345016-230548_585641154.0RepeatNote=HEAT 11
HgeneAP3D1chr19:2138618chr16:67354788ENST00000345016-23077_114641154.0RepeatNote=HEAT 2
HgeneAP3D1chr19:2138618chr16:67354788ENST00000355272-232142_179641216.0RepeatNote=HEAT 3
HgeneAP3D1chr19:2138618chr16:67354788ENST00000355272-232180_216641216.0RepeatNote=HEAT 4
HgeneAP3D1chr19:2138618chr16:67354788ENST00000355272-232254_292641216.0RepeatNote=HEAT 5
HgeneAP3D1chr19:2138618chr16:67354788ENST00000355272-232299_336641216.0RepeatNote=HEAT 6
HgeneAP3D1chr19:2138618chr16:67354788ENST00000355272-232338_373641216.0RepeatNote=HEAT 7
HgeneAP3D1chr19:2138618chr16:67354788ENST00000355272-23234_71641216.0RepeatNote=HEAT 1
HgeneAP3D1chr19:2138618chr16:67354788ENST00000355272-232375_409641216.0RepeatNote=HEAT 8
HgeneAP3D1chr19:2138618chr16:67354788ENST00000355272-232431_468641216.0RepeatNote=HEAT 9
HgeneAP3D1chr19:2138618chr16:67354788ENST00000355272-232497_535641216.0RepeatNote=HEAT 10
HgeneAP3D1chr19:2138618chr16:67354788ENST00000355272-232548_585641216.0RepeatNote=HEAT 11
HgeneAP3D1chr19:2138618chr16:67354788ENST00000355272-23277_114641216.0RepeatNote=HEAT 2


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Fusion Gene Sequence for AP3D1-KCTD19


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>5277_5277_1_AP3D1-KCTD19_AP3D1_chr19_2137726_ENST00000345016_KCTD19_chr16_67354788_ENST00000304372_length(transcript)=3404nt_BP=505nt
GCCGCCATCTTGTCCGCCATTTGCAAGGGGCCCGGAGCGGGATCGCGGCACCTGCCGAGCGGGTCGCCGCCTCTGCCGCGGTCCTTGGAC
CCCGCCGCCGCCCTGGCCTGGGAGCTTGCCCCGCCGCAGCGGCCGGCAGCGCGGCGCTCCGCGGGCGGCAGGCACGGGCCCCGGGCCCCC
TCACGGCGCCCAGCCGCGGGCCTCCCGAGGCAAAAGCCCGTGGGCCGCCGCGATGGCCCTCAAGATGGTGAAGGGCAGCATCGACCGCAT
GTTCGACAAGAATCTGCAGGACTTGGTCCGCGGCATCCGTAACCACAAGGAGGACGAGGCAAAATACATATCTCAGTGCATTGATGAGAT
CAAGCAGGAGCTGAAGCAGGACAACATAGCGGTGAAGGCGAACGCGGTCTGCAAGCTGACGTATTTACAGATGTTGGGATACGACATCAG
CTGGGCCGCCTTCAACATCATAGAAGTGATGAGTGCCTCCAAGTTCACCTTCAAGGAGGAGTCTGGCATGGCTCATGAATCAGCAGAGGA
CTTGTTTCATTTCAACGTAGGGGGCTGGCATTTCTCAGTTCCCAGAAGCAAACTCTCTCAGTTTCCAGACTCCCTGCTGTGGAAAGAGGC
TTCAGCCTTGACCTCTTCAGAAAGCCAGAGGCTATTTATCGACAGAGATGGTTCCACATTTAGGCACGTGCACTATTACCTCTACACCTC
CAAACTCTCCTTCTCCAGTTGTGCAGAACTGAACTTGCTGTATGAGCAAGCATTGGGTTTGCAGCTGATGCCTTTGCTGCAGACTCTAGA
TAACCTGAAGGAAGGGAAACACCATCTACGCGTACGGCCTGCAGACCTACCTGTTGCTGAGAGAGCATCTCTGAACTACTGGCGTACATG
GAAGTGTATTAGCAAACCCTCAGAATTTCCAATTAAAAGCCCAGCCTTTACAGGCCTACATGATAAGGCACCTCTGGGGCTCATGGACAC
ACCCCTGTTAGACACAGAAGAGGAGGTGCACTACTGCTTCCTGCCCCTAGACCTGGTGGCCAAATATCCCAGCCTAGTGACTGAAGACAA
CCTGCTGTGGCTGGCTGAGACGGTGGCCCTCATCGAGTGCGAGTGCAGCGAGTTCCGCTTCATTGTGAATTTTCTTCGCTCACAGAAGAT
TTTACTACCGGATAATTTCTCCAACATTGATGTATTAGAAGCAGAAGTGGAAATTCTGGAAATCCCTGCACTCACTGAAGCCGTAAGGTG
GTACCGGATGAACATGGGTGGCTGTTCCCCGACCACCTGTTCTCCCCTGAGCCCCGGGAAGGGGGCCCGCACAGCCAGCCTGGAGTCCGT
GAAACCGCTCTACACAATGGCCCTGGGTCTGCTGGTCAAGTACCCGGACTCTGCGCTGGGCCAGCTTCGCATCGAGAGCACGCTAGACGG
AAGCCGACTGTACATCACAGGGAATGGCGTCCTCTTTCAGCACGTCAAGAACTGGCTGGGGACTTGCCGGCTGCCCCTGACAGAGACCAT
TTCCGAGGTATATGAGCTCTGTGCCTTCCTAGACAAAAGGGACATCACCTACGAGCCAATCAAAGTTGCTTTGAAGACTCATCTGGAGCC
AAGGACTTTGGCACCCATGGATGTGCTCAATGAGTGGACGGCAGAGATCACTGTGTATTCCCCACAACAGATCATCAAAGTGTATGTTGG
AAGCCACTGGTACGCAACCACCCTGCAGACACTGCTGAAGTATCCAGAACTGCTGTCCAACCCTCAGAGAGTGTACTGGATCACATATGG
ACAAACCCTGCTCATCCACGGGGATGGCCAGATGTTCCGACACATTCTCAACTTCCTGAGACTTGGCAAACTGTTTTTACCATCTGAATT
TAAGGAATGGCCCCTCTTCTGCCAGGAGGTGGAGGAATACCACATTCCATCCCTCTCAGAAGCCCTTGCACAATGTGAAGCATACAAGTC
ATGGACTCAGGAGAAAGAATCTGAAAATGAAGAAGCTTTTTCCATCAGGAGGCTGCATGTGGTGACAGAAGGGCCAGGGTCACTGGTGGA
GTTCAGTAGAGACACTAAAGAAACCACAGCCTACATGCCTGTGGACTTCGAAGACTGCAGTGACAGGACTCCATGGAACAAGGCTAAGGG
AAACCTGGTCAGGTCCAACCAGATGGATGAGGCTGAGCAGTACACTCGGCCCATCCAGGTGTCCCTATGCCGAAATGCCAAGAGGGCTGG
CAACCCTAGCACATACTCACACTGCCGTGGCTTGTGTACCAATCCTGGACACTGGGGGAGCCACCCTGAGAGCCCCCCAAAGAAGAAATG
CACCACAATCAACCTCACACAGAAATCTGAAACCAAAGACCCTCCCGCCACTCCCATGCAAAAACTCATCTCCCTGGTGAGAGAATGGGA
CATGGTCAATTGCAAACAGTGGGAATTCCAGCCACTGACAGCCACACGGAGCAGCCCCTTGGAGGAGGCCACCCTGCAGCTCCCCTTGGG
AAGCGAGGCTGCTTCCCAGCCCAGCACCTCAGCTGCCTGGAAAGCCCATTCCACAGCCTCAGAGAAGGATCCAGGACCACAGGCAGGGGC
TGGAGCTGGAGCGAAAGACAAGGGGCCAGAGCCAACCTTCAAGCCATACTTACCCCCAAAAAGAGCTGGCACCCTGAAGGACTGGAGCAA
GCAGAGGACCAAGGAGAGAGAAAGCCCTGCCCCTGAGCAGCCTCTGCCCGAGGCCAGTGAGGTGGACAGCCTAGGGGTTATCCTCAAAGT
GACTCACCCCCCCGTGGTGGGCAGCGATGGCTTCTGCATGTTCTTTGAGGACAGCATCATCTATACCACGGAGATGGACAACCTCAGGCA
CACAACACCCACAGCCAGTCCCCAGCCCCAAGAAGTGACTTTCCTGAGTTTCTCTCTGTCCTGGGAAGAGATGTTTTATGCACAGAAATG
TCACTGCTTCCTGGCTGACATCATCATGGATTCCATCAGGCAAAAGGACCCCAAAGCCATCACAGCCAAGGTGGTCTCCCTGGCCAATCG
GCTGTGGACCCTGCACATCAGCCCCAAGCAGTTTGTGGTAGATTTGCTGGCCATCACCGGCTTCAAGGATGACCGGCACACCCAGGAGCG
CCTGTACAGCTGGGTGGAGCTTACACTGCCCTTCGCCAGGAAATATGGCCGATGCATGGACCTGCTCATCCAGAGGGGCCTGTCTAGGTC
TGTCTCTTACTCCATCCTGGGAAAGTACCTACAAGAGGACTAGGGTGCCCAGAGATGCAGCCCCTCATGCCCCACCCGCCAAGTCTCATT

>5277_5277_1_AP3D1-KCTD19_AP3D1_chr19_2137726_ENST00000345016_KCTD19_chr16_67354788_ENST00000304372_length(amino acids)=1055AA_BP=130
MPRRSGRQRGAPRAAGTGPGPPHGAQPRASRGKSPWAAAMALKMVKGSIDRMFDKNLQDLVRGIRNHKEDEAKYISQCIDEIKQELKQDN
IAVKANAVCKLTYLQMLGYDISWAAFNIIEVMSASKFTFKEESGMAHESAEDLFHFNVGGWHFSVPRSKLSQFPDSLLWKEASALTSSES
QRLFIDRDGSTFRHVHYYLYTSKLSFSSCAELNLLYEQALGLQLMPLLQTLDNLKEGKHHLRVRPADLPVAERASLNYWRTWKCISKPSE
FPIKSPAFTGLHDKAPLGLMDTPLLDTEEEVHYCFLPLDLVAKYPSLVTEDNLLWLAETVALIECECSEFRFIVNFLRSQKILLPDNFSN
IDVLEAEVEILEIPALTEAVRWYRMNMGGCSPTTCSPLSPGKGARTASLESVKPLYTMALGLLVKYPDSALGQLRIESTLDGSRLYITGN
GVLFQHVKNWLGTCRLPLTETISEVYELCAFLDKRDITYEPIKVALKTHLEPRTLAPMDVLNEWTAEITVYSPQQIIKVYVGSHWYATTL
QTLLKYPELLSNPQRVYWITYGQTLLIHGDGQMFRHILNFLRLGKLFLPSEFKEWPLFCQEVEEYHIPSLSEALAQCEAYKSWTQEKESE
NEEAFSIRRLHVVTEGPGSLVEFSRDTKETTAYMPVDFEDCSDRTPWNKAKGNLVRSNQMDEAEQYTRPIQVSLCRNAKRAGNPSTYSHC
RGLCTNPGHWGSHPESPPKKKCTTINLTQKSETKDPPATPMQKLISLVREWDMVNCKQWEFQPLTATRSSPLEEATLQLPLGSEAASQPS
TSAAWKAHSTASEKDPGPQAGAGAGAKDKGPEPTFKPYLPPKRAGTLKDWSKQRTKERESPAPEQPLPEASEVDSLGVILKVTHPPVVGS
DGFCMFFEDSIIYTTEMDNLRHTTPTASPQPQEVTFLSFSLSWEEMFYAQKCHCFLADIIMDSIRQKDPKAITAKVVSLANRLWTLHISP

--------------------------------------------------------------
>5277_5277_2_AP3D1-KCTD19_AP3D1_chr19_2137726_ENST00000350812_KCTD19_chr16_67354788_ENST00000304372_length(transcript)=3378nt_BP=479nt
GGGGCCCGGAGCGGGATCGCGGCACCTGCCGAGCGGGTCGCCGCCTCTGCCGCGGTCCTTGGACCCCGCCGCCGCCCTGGCCTGGGAGCT
TGCCCCGCCGCAGCGGCCGGCAGCGCGGCGCTCCGCGGGCGGCAGGCACGGGCCCCGGGCCCCCTCACGGCGCCCAGCCGCGGGCCTCCC
GAGGCAAAAGCCCGTGGGCCGCCGCGATGGCCCTCAAGATGGTGAAGGGCAGCATCGACCGCATGTTCGACAAGAATCTGCAGGACTTGG
TCCGCGGCATCCGTAACCACAAGGAGGACGAGGCAAAATACATATCTCAGTGCATTGATGAGATCAAGCAGGAGCTGAAGCAGGACAACA
TAGCGGTGAAGGCGAACGCGGTCTGCAAGCTGACGTATTTACAGATGTTGGGATACGACATCAGCTGGGCCGCCTTCAACATCATAGAAG
TGATGAGTGCCTCCAAGTTCACCTTCAAGGAGGAGTCTGGCATGGCTCATGAATCAGCAGAGGACTTGTTTCATTTCAACGTAGGGGGCT
GGCATTTCTCAGTTCCCAGAAGCAAACTCTCTCAGTTTCCAGACTCCCTGCTGTGGAAAGAGGCTTCAGCCTTGACCTCTTCAGAAAGCC
AGAGGCTATTTATCGACAGAGATGGTTCCACATTTAGGCACGTGCACTATTACCTCTACACCTCCAAACTCTCCTTCTCCAGTTGTGCAG
AACTGAACTTGCTGTATGAGCAAGCATTGGGTTTGCAGCTGATGCCTTTGCTGCAGACTCTAGATAACCTGAAGGAAGGGAAACACCATC
TACGCGTACGGCCTGCAGACCTACCTGTTGCTGAGAGAGCATCTCTGAACTACTGGCGTACATGGAAGTGTATTAGCAAACCCTCAGAAT
TTCCAATTAAAAGCCCAGCCTTTACAGGCCTACATGATAAGGCACCTCTGGGGCTCATGGACACACCCCTGTTAGACACAGAAGAGGAGG
TGCACTACTGCTTCCTGCCCCTAGACCTGGTGGCCAAATATCCCAGCCTAGTGACTGAAGACAACCTGCTGTGGCTGGCTGAGACGGTGG
CCCTCATCGAGTGCGAGTGCAGCGAGTTCCGCTTCATTGTGAATTTTCTTCGCTCACAGAAGATTTTACTACCGGATAATTTCTCCAACA
TTGATGTATTAGAAGCAGAAGTGGAAATTCTGGAAATCCCTGCACTCACTGAAGCCGTAAGGTGGTACCGGATGAACATGGGTGGCTGTT
CCCCGACCACCTGTTCTCCCCTGAGCCCCGGGAAGGGGGCCCGCACAGCCAGCCTGGAGTCCGTGAAACCGCTCTACACAATGGCCCTGG
GTCTGCTGGTCAAGTACCCGGACTCTGCGCTGGGCCAGCTTCGCATCGAGAGCACGCTAGACGGAAGCCGACTGTACATCACAGGGAATG
GCGTCCTCTTTCAGCACGTCAAGAACTGGCTGGGGACTTGCCGGCTGCCCCTGACAGAGACCATTTCCGAGGTATATGAGCTCTGTGCCT
TCCTAGACAAAAGGGACATCACCTACGAGCCAATCAAAGTTGCTTTGAAGACTCATCTGGAGCCAAGGACTTTGGCACCCATGGATGTGC
TCAATGAGTGGACGGCAGAGATCACTGTGTATTCCCCACAACAGATCATCAAAGTGTATGTTGGAAGCCACTGGTACGCAACCACCCTGC
AGACACTGCTGAAGTATCCAGAACTGCTGTCCAACCCTCAGAGAGTGTACTGGATCACATATGGACAAACCCTGCTCATCCACGGGGATG
GCCAGATGTTCCGACACATTCTCAACTTCCTGAGACTTGGCAAACTGTTTTTACCATCTGAATTTAAGGAATGGCCCCTCTTCTGCCAGG
AGGTGGAGGAATACCACATTCCATCCCTCTCAGAAGCCCTTGCACAATGTGAAGCATACAAGTCATGGACTCAGGAGAAAGAATCTGAAA
ATGAAGAAGCTTTTTCCATCAGGAGGCTGCATGTGGTGACAGAAGGGCCAGGGTCACTGGTGGAGTTCAGTAGAGACACTAAAGAAACCA
CAGCCTACATGCCTGTGGACTTCGAAGACTGCAGTGACAGGACTCCATGGAACAAGGCTAAGGGAAACCTGGTCAGGTCCAACCAGATGG
ATGAGGCTGAGCAGTACACTCGGCCCATCCAGGTGTCCCTATGCCGAAATGCCAAGAGGGCTGGCAACCCTAGCACATACTCACACTGCC
GTGGCTTGTGTACCAATCCTGGACACTGGGGGAGCCACCCTGAGAGCCCCCCAAAGAAGAAATGCACCACAATCAACCTCACACAGAAAT
CTGAAACCAAAGACCCTCCCGCCACTCCCATGCAAAAACTCATCTCCCTGGTGAGAGAATGGGACATGGTCAATTGCAAACAGTGGGAAT
TCCAGCCACTGACAGCCACACGGAGCAGCCCCTTGGAGGAGGCCACCCTGCAGCTCCCCTTGGGAAGCGAGGCTGCTTCCCAGCCCAGCA
CCTCAGCTGCCTGGAAAGCCCATTCCACAGCCTCAGAGAAGGATCCAGGACCACAGGCAGGGGCTGGAGCTGGAGCGAAAGACAAGGGGC
CAGAGCCAACCTTCAAGCCATACTTACCCCCAAAAAGAGCTGGCACCCTGAAGGACTGGAGCAAGCAGAGGACCAAGGAGAGAGAAAGCC
CTGCCCCTGAGCAGCCTCTGCCCGAGGCCAGTGAGGTGGACAGCCTAGGGGTTATCCTCAAAGTGACTCACCCCCCCGTGGTGGGCAGCG
ATGGCTTCTGCATGTTCTTTGAGGACAGCATCATCTATACCACGGAGATGGACAACCTCAGGCACACAACACCCACAGCCAGTCCCCAGC
CCCAAGAAGTGACTTTCCTGAGTTTCTCTCTGTCCTGGGAAGAGATGTTTTATGCACAGAAATGTCACTGCTTCCTGGCTGACATCATCA
TGGATTCCATCAGGCAAAAGGACCCCAAAGCCATCACAGCCAAGGTGGTCTCCCTGGCCAATCGGCTGTGGACCCTGCACATCAGCCCCA
AGCAGTTTGTGGTAGATTTGCTGGCCATCACCGGCTTCAAGGATGACCGGCACACCCAGGAGCGCCTGTACAGCTGGGTGGAGCTTACAC
TGCCCTTCGCCAGGAAATATGGCCGATGCATGGACCTGCTCATCCAGAGGGGCCTGTCTAGGTCTGTCTCTTACTCCATCCTGGGAAAGT
ACCTACAAGAGGACTAGGGTGCCCAGAGATGCAGCCCCTCATGCCCCACCCGCCAAGTCTCATTTTAATTGGAGATAGCCCAGAATGCAT

>5277_5277_2_AP3D1-KCTD19_AP3D1_chr19_2137726_ENST00000350812_KCTD19_chr16_67354788_ENST00000304372_length(amino acids)=1055AA_BP=130
MPRRSGRQRGAPRAAGTGPGPPHGAQPRASRGKSPWAAAMALKMVKGSIDRMFDKNLQDLVRGIRNHKEDEAKYISQCIDEIKQELKQDN
IAVKANAVCKLTYLQMLGYDISWAAFNIIEVMSASKFTFKEESGMAHESAEDLFHFNVGGWHFSVPRSKLSQFPDSLLWKEASALTSSES
QRLFIDRDGSTFRHVHYYLYTSKLSFSSCAELNLLYEQALGLQLMPLLQTLDNLKEGKHHLRVRPADLPVAERASLNYWRTWKCISKPSE
FPIKSPAFTGLHDKAPLGLMDTPLLDTEEEVHYCFLPLDLVAKYPSLVTEDNLLWLAETVALIECECSEFRFIVNFLRSQKILLPDNFSN
IDVLEAEVEILEIPALTEAVRWYRMNMGGCSPTTCSPLSPGKGARTASLESVKPLYTMALGLLVKYPDSALGQLRIESTLDGSRLYITGN
GVLFQHVKNWLGTCRLPLTETISEVYELCAFLDKRDITYEPIKVALKTHLEPRTLAPMDVLNEWTAEITVYSPQQIIKVYVGSHWYATTL
QTLLKYPELLSNPQRVYWITYGQTLLIHGDGQMFRHILNFLRLGKLFLPSEFKEWPLFCQEVEEYHIPSLSEALAQCEAYKSWTQEKESE
NEEAFSIRRLHVVTEGPGSLVEFSRDTKETTAYMPVDFEDCSDRTPWNKAKGNLVRSNQMDEAEQYTRPIQVSLCRNAKRAGNPSTYSHC
RGLCTNPGHWGSHPESPPKKKCTTINLTQKSETKDPPATPMQKLISLVREWDMVNCKQWEFQPLTATRSSPLEEATLQLPLGSEAASQPS
TSAAWKAHSTASEKDPGPQAGAGAGAKDKGPEPTFKPYLPPKRAGTLKDWSKQRTKERESPAPEQPLPEASEVDSLGVILKVTHPPVVGS
DGFCMFFEDSIIYTTEMDNLRHTTPTASPQPQEVTFLSFSLSWEEMFYAQKCHCFLADIIMDSIRQKDPKAITAKVVSLANRLWTLHISP

--------------------------------------------------------------
>5277_5277_3_AP3D1-KCTD19_AP3D1_chr19_2137726_ENST00000355272_KCTD19_chr16_67354788_ENST00000304372_length(transcript)=3379nt_BP=480nt
AGGGGCCCGGAGCGGGATCGCGGCACCTGCCGAGCGGGTCGCCGCCTCTGCCGCGGTCCTTGGACCCCGCCGCCGCCCTGGCCTGGGAGC
TTGCCCCGCCGCAGCGGCCGGCAGCGCGGCGCTCCGCGGGCGGCAGGCACGGGCCCCGGGCCCCCTCACGGCGCCCAGCCGCGGGCCTCC
CGAGGCAAAAGCCCGTGGGCCGCCGCGATGGCCCTCAAGATGGTGAAGGGCAGCATCGACCGCATGTTCGACAAGAATCTGCAGGACTTG
GTCCGCGGCATCCGTAACCACAAGGAGGACGAGGCAAAATACATATCTCAGTGCATTGATGAGATCAAGCAGGAGCTGAAGCAGGACAAC
ATAGCGGTGAAGGCGAACGCGGTCTGCAAGCTGACGTATTTACAGATGTTGGGATACGACATCAGCTGGGCCGCCTTCAACATCATAGAA
GTGATGAGTGCCTCCAAGTTCACCTTCAAGGAGGAGTCTGGCATGGCTCATGAATCAGCAGAGGACTTGTTTCATTTCAACGTAGGGGGC
TGGCATTTCTCAGTTCCCAGAAGCAAACTCTCTCAGTTTCCAGACTCCCTGCTGTGGAAAGAGGCTTCAGCCTTGACCTCTTCAGAAAGC
CAGAGGCTATTTATCGACAGAGATGGTTCCACATTTAGGCACGTGCACTATTACCTCTACACCTCCAAACTCTCCTTCTCCAGTTGTGCA
GAACTGAACTTGCTGTATGAGCAAGCATTGGGTTTGCAGCTGATGCCTTTGCTGCAGACTCTAGATAACCTGAAGGAAGGGAAACACCAT
CTACGCGTACGGCCTGCAGACCTACCTGTTGCTGAGAGAGCATCTCTGAACTACTGGCGTACATGGAAGTGTATTAGCAAACCCTCAGAA
TTTCCAATTAAAAGCCCAGCCTTTACAGGCCTACATGATAAGGCACCTCTGGGGCTCATGGACACACCCCTGTTAGACACAGAAGAGGAG
GTGCACTACTGCTTCCTGCCCCTAGACCTGGTGGCCAAATATCCCAGCCTAGTGACTGAAGACAACCTGCTGTGGCTGGCTGAGACGGTG
GCCCTCATCGAGTGCGAGTGCAGCGAGTTCCGCTTCATTGTGAATTTTCTTCGCTCACAGAAGATTTTACTACCGGATAATTTCTCCAAC
ATTGATGTATTAGAAGCAGAAGTGGAAATTCTGGAAATCCCTGCACTCACTGAAGCCGTAAGGTGGTACCGGATGAACATGGGTGGCTGT
TCCCCGACCACCTGTTCTCCCCTGAGCCCCGGGAAGGGGGCCCGCACAGCCAGCCTGGAGTCCGTGAAACCGCTCTACACAATGGCCCTG
GGTCTGCTGGTCAAGTACCCGGACTCTGCGCTGGGCCAGCTTCGCATCGAGAGCACGCTAGACGGAAGCCGACTGTACATCACAGGGAAT
GGCGTCCTCTTTCAGCACGTCAAGAACTGGCTGGGGACTTGCCGGCTGCCCCTGACAGAGACCATTTCCGAGGTATATGAGCTCTGTGCC
TTCCTAGACAAAAGGGACATCACCTACGAGCCAATCAAAGTTGCTTTGAAGACTCATCTGGAGCCAAGGACTTTGGCACCCATGGATGTG
CTCAATGAGTGGACGGCAGAGATCACTGTGTATTCCCCACAACAGATCATCAAAGTGTATGTTGGAAGCCACTGGTACGCAACCACCCTG
CAGACACTGCTGAAGTATCCAGAACTGCTGTCCAACCCTCAGAGAGTGTACTGGATCACATATGGACAAACCCTGCTCATCCACGGGGAT
GGCCAGATGTTCCGACACATTCTCAACTTCCTGAGACTTGGCAAACTGTTTTTACCATCTGAATTTAAGGAATGGCCCCTCTTCTGCCAG
GAGGTGGAGGAATACCACATTCCATCCCTCTCAGAAGCCCTTGCACAATGTGAAGCATACAAGTCATGGACTCAGGAGAAAGAATCTGAA
AATGAAGAAGCTTTTTCCATCAGGAGGCTGCATGTGGTGACAGAAGGGCCAGGGTCACTGGTGGAGTTCAGTAGAGACACTAAAGAAACC
ACAGCCTACATGCCTGTGGACTTCGAAGACTGCAGTGACAGGACTCCATGGAACAAGGCTAAGGGAAACCTGGTCAGGTCCAACCAGATG
GATGAGGCTGAGCAGTACACTCGGCCCATCCAGGTGTCCCTATGCCGAAATGCCAAGAGGGCTGGCAACCCTAGCACATACTCACACTGC
CGTGGCTTGTGTACCAATCCTGGACACTGGGGGAGCCACCCTGAGAGCCCCCCAAAGAAGAAATGCACCACAATCAACCTCACACAGAAA
TCTGAAACCAAAGACCCTCCCGCCACTCCCATGCAAAAACTCATCTCCCTGGTGAGAGAATGGGACATGGTCAATTGCAAACAGTGGGAA
TTCCAGCCACTGACAGCCACACGGAGCAGCCCCTTGGAGGAGGCCACCCTGCAGCTCCCCTTGGGAAGCGAGGCTGCTTCCCAGCCCAGC
ACCTCAGCTGCCTGGAAAGCCCATTCCACAGCCTCAGAGAAGGATCCAGGACCACAGGCAGGGGCTGGAGCTGGAGCGAAAGACAAGGGG
CCAGAGCCAACCTTCAAGCCATACTTACCCCCAAAAAGAGCTGGCACCCTGAAGGACTGGAGCAAGCAGAGGACCAAGGAGAGAGAAAGC
CCTGCCCCTGAGCAGCCTCTGCCCGAGGCCAGTGAGGTGGACAGCCTAGGGGTTATCCTCAAAGTGACTCACCCCCCCGTGGTGGGCAGC
GATGGCTTCTGCATGTTCTTTGAGGACAGCATCATCTATACCACGGAGATGGACAACCTCAGGCACACAACACCCACAGCCAGTCCCCAG
CCCCAAGAAGTGACTTTCCTGAGTTTCTCTCTGTCCTGGGAAGAGATGTTTTATGCACAGAAATGTCACTGCTTCCTGGCTGACATCATC
ATGGATTCCATCAGGCAAAAGGACCCCAAAGCCATCACAGCCAAGGTGGTCTCCCTGGCCAATCGGCTGTGGACCCTGCACATCAGCCCC
AAGCAGTTTGTGGTAGATTTGCTGGCCATCACCGGCTTCAAGGATGACCGGCACACCCAGGAGCGCCTGTACAGCTGGGTGGAGCTTACA
CTGCCCTTCGCCAGGAAATATGGCCGATGCATGGACCTGCTCATCCAGAGGGGCCTGTCTAGGTCTGTCTCTTACTCCATCCTGGGAAAG
TACCTACAAGAGGACTAGGGTGCCCAGAGATGCAGCCCCTCATGCCCCACCCGCCAAGTCTCATTTTAATTGGAGATAGCCCAGAATGCA

>5277_5277_3_AP3D1-KCTD19_AP3D1_chr19_2137726_ENST00000355272_KCTD19_chr16_67354788_ENST00000304372_length(amino acids)=1055AA_BP=130
MPRRSGRQRGAPRAAGTGPGPPHGAQPRASRGKSPWAAAMALKMVKGSIDRMFDKNLQDLVRGIRNHKEDEAKYISQCIDEIKQELKQDN
IAVKANAVCKLTYLQMLGYDISWAAFNIIEVMSASKFTFKEESGMAHESAEDLFHFNVGGWHFSVPRSKLSQFPDSLLWKEASALTSSES
QRLFIDRDGSTFRHVHYYLYTSKLSFSSCAELNLLYEQALGLQLMPLLQTLDNLKEGKHHLRVRPADLPVAERASLNYWRTWKCISKPSE
FPIKSPAFTGLHDKAPLGLMDTPLLDTEEEVHYCFLPLDLVAKYPSLVTEDNLLWLAETVALIECECSEFRFIVNFLRSQKILLPDNFSN
IDVLEAEVEILEIPALTEAVRWYRMNMGGCSPTTCSPLSPGKGARTASLESVKPLYTMALGLLVKYPDSALGQLRIESTLDGSRLYITGN
GVLFQHVKNWLGTCRLPLTETISEVYELCAFLDKRDITYEPIKVALKTHLEPRTLAPMDVLNEWTAEITVYSPQQIIKVYVGSHWYATTL
QTLLKYPELLSNPQRVYWITYGQTLLIHGDGQMFRHILNFLRLGKLFLPSEFKEWPLFCQEVEEYHIPSLSEALAQCEAYKSWTQEKESE
NEEAFSIRRLHVVTEGPGSLVEFSRDTKETTAYMPVDFEDCSDRTPWNKAKGNLVRSNQMDEAEQYTRPIQVSLCRNAKRAGNPSTYSHC
RGLCTNPGHWGSHPESPPKKKCTTINLTQKSETKDPPATPMQKLISLVREWDMVNCKQWEFQPLTATRSSPLEEATLQLPLGSEAASQPS
TSAAWKAHSTASEKDPGPQAGAGAGAKDKGPEPTFKPYLPPKRAGTLKDWSKQRTKERESPAPEQPLPEASEVDSLGVILKVTHPPVVGS
DGFCMFFEDSIIYTTEMDNLRHTTPTASPQPQEVTFLSFSLSWEEMFYAQKCHCFLADIIMDSIRQKDPKAITAKVVSLANRLWTLHISP

--------------------------------------------------------------
>5277_5277_4_AP3D1-KCTD19_AP3D1_chr19_2137726_ENST00000356926_KCTD19_chr16_67354788_ENST00000304372_length(transcript)=3395nt_BP=496nt
TTGTCCGCCATTTGCAAGGGGCCCGGAGCGGGATCGCGGCACCTGCCGAGCGGGTCGCCGCCTCTGCCGCGGTCCTTGGACCCCGCCGCC
GCCCTGGCCTGGGAGCTTGCCCCGCCGCAGCGGCCGGCAGCGCGGCGCTCCGCGGGCGGCAGGCACGGGCCCCGGGCCCCCTCACGGCGC
CCAGCCGCGGGCCTCCCGAGGCAAAAGCCCGTGGGCCGCCGCGATGGCCCTCAAGATGGTGAAGGGCAGCATCGACCGCATGTTCGACAA
GAATCTGCAGGACTTGGTCCGCGGCATCCGTAACCACAAGGAGGACGAGGCAAAATACATATCTCAGTGCATTGATGAGATCAAGCAGGA
GCTGAAGCAGGACAACATAGCGGTGAAGGCGAACGCGGTCTGCAAGCTGACGTATTTACAGATGTTGGGATACGACATCAGCTGGGCCGC
CTTCAACATCATAGAAGTGATGAGTGCCTCCAAGTTCACCTTCAAGGAGGAGTCTGGCATGGCTCATGAATCAGCAGAGGACTTGTTTCA
TTTCAACGTAGGGGGCTGGCATTTCTCAGTTCCCAGAAGCAAACTCTCTCAGTTTCCAGACTCCCTGCTGTGGAAAGAGGCTTCAGCCTT
GACCTCTTCAGAAAGCCAGAGGCTATTTATCGACAGAGATGGTTCCACATTTAGGCACGTGCACTATTACCTCTACACCTCCAAACTCTC
CTTCTCCAGTTGTGCAGAACTGAACTTGCTGTATGAGCAAGCATTGGGTTTGCAGCTGATGCCTTTGCTGCAGACTCTAGATAACCTGAA
GGAAGGGAAACACCATCTACGCGTACGGCCTGCAGACCTACCTGTTGCTGAGAGAGCATCTCTGAACTACTGGCGTACATGGAAGTGTAT
TAGCAAACCCTCAGAATTTCCAATTAAAAGCCCAGCCTTTACAGGCCTACATGATAAGGCACCTCTGGGGCTCATGGACACACCCCTGTT
AGACACAGAAGAGGAGGTGCACTACTGCTTCCTGCCCCTAGACCTGGTGGCCAAATATCCCAGCCTAGTGACTGAAGACAACCTGCTGTG
GCTGGCTGAGACGGTGGCCCTCATCGAGTGCGAGTGCAGCGAGTTCCGCTTCATTGTGAATTTTCTTCGCTCACAGAAGATTTTACTACC
GGATAATTTCTCCAACATTGATGTATTAGAAGCAGAAGTGGAAATTCTGGAAATCCCTGCACTCACTGAAGCCGTAAGGTGGTACCGGAT
GAACATGGGTGGCTGTTCCCCGACCACCTGTTCTCCCCTGAGCCCCGGGAAGGGGGCCCGCACAGCCAGCCTGGAGTCCGTGAAACCGCT
CTACACAATGGCCCTGGGTCTGCTGGTCAAGTACCCGGACTCTGCGCTGGGCCAGCTTCGCATCGAGAGCACGCTAGACGGAAGCCGACT
GTACATCACAGGGAATGGCGTCCTCTTTCAGCACGTCAAGAACTGGCTGGGGACTTGCCGGCTGCCCCTGACAGAGACCATTTCCGAGGT
ATATGAGCTCTGTGCCTTCCTAGACAAAAGGGACATCACCTACGAGCCAATCAAAGTTGCTTTGAAGACTCATCTGGAGCCAAGGACTTT
GGCACCCATGGATGTGCTCAATGAGTGGACGGCAGAGATCACTGTGTATTCCCCACAACAGATCATCAAAGTGTATGTTGGAAGCCACTG
GTACGCAACCACCCTGCAGACACTGCTGAAGTATCCAGAACTGCTGTCCAACCCTCAGAGAGTGTACTGGATCACATATGGACAAACCCT
GCTCATCCACGGGGATGGCCAGATGTTCCGACACATTCTCAACTTCCTGAGACTTGGCAAACTGTTTTTACCATCTGAATTTAAGGAATG
GCCCCTCTTCTGCCAGGAGGTGGAGGAATACCACATTCCATCCCTCTCAGAAGCCCTTGCACAATGTGAAGCATACAAGTCATGGACTCA
GGAGAAAGAATCTGAAAATGAAGAAGCTTTTTCCATCAGGAGGCTGCATGTGGTGACAGAAGGGCCAGGGTCACTGGTGGAGTTCAGTAG
AGACACTAAAGAAACCACAGCCTACATGCCTGTGGACTTCGAAGACTGCAGTGACAGGACTCCATGGAACAAGGCTAAGGGAAACCTGGT
CAGGTCCAACCAGATGGATGAGGCTGAGCAGTACACTCGGCCCATCCAGGTGTCCCTATGCCGAAATGCCAAGAGGGCTGGCAACCCTAG
CACATACTCACACTGCCGTGGCTTGTGTACCAATCCTGGACACTGGGGGAGCCACCCTGAGAGCCCCCCAAAGAAGAAATGCACCACAAT
CAACCTCACACAGAAATCTGAAACCAAAGACCCTCCCGCCACTCCCATGCAAAAACTCATCTCCCTGGTGAGAGAATGGGACATGGTCAA
TTGCAAACAGTGGGAATTCCAGCCACTGACAGCCACACGGAGCAGCCCCTTGGAGGAGGCCACCCTGCAGCTCCCCTTGGGAAGCGAGGC
TGCTTCCCAGCCCAGCACCTCAGCTGCCTGGAAAGCCCATTCCACAGCCTCAGAGAAGGATCCAGGACCACAGGCAGGGGCTGGAGCTGG
AGCGAAAGACAAGGGGCCAGAGCCAACCTTCAAGCCATACTTACCCCCAAAAAGAGCTGGCACCCTGAAGGACTGGAGCAAGCAGAGGAC
CAAGGAGAGAGAAAGCCCTGCCCCTGAGCAGCCTCTGCCCGAGGCCAGTGAGGTGGACAGCCTAGGGGTTATCCTCAAAGTGACTCACCC
CCCCGTGGTGGGCAGCGATGGCTTCTGCATGTTCTTTGAGGACAGCATCATCTATACCACGGAGATGGACAACCTCAGGCACACAACACC
CACAGCCAGTCCCCAGCCCCAAGAAGTGACTTTCCTGAGTTTCTCTCTGTCCTGGGAAGAGATGTTTTATGCACAGAAATGTCACTGCTT
CCTGGCTGACATCATCATGGATTCCATCAGGCAAAAGGACCCCAAAGCCATCACAGCCAAGGTGGTCTCCCTGGCCAATCGGCTGTGGAC
CCTGCACATCAGCCCCAAGCAGTTTGTGGTAGATTTGCTGGCCATCACCGGCTTCAAGGATGACCGGCACACCCAGGAGCGCCTGTACAG
CTGGGTGGAGCTTACACTGCCCTTCGCCAGGAAATATGGCCGATGCATGGACCTGCTCATCCAGAGGGGCCTGTCTAGGTCTGTCTCTTA
CTCCATCCTGGGAAAGTACCTACAAGAGGACTAGGGTGCCCAGAGATGCAGCCCCTCATGCCCCACCCGCCAAGTCTCATTTTAATTGGA

>5277_5277_4_AP3D1-KCTD19_AP3D1_chr19_2137726_ENST00000356926_KCTD19_chr16_67354788_ENST00000304372_length(amino acids)=1055AA_BP=130
MPRRSGRQRGAPRAAGTGPGPPHGAQPRASRGKSPWAAAMALKMVKGSIDRMFDKNLQDLVRGIRNHKEDEAKYISQCIDEIKQELKQDN
IAVKANAVCKLTYLQMLGYDISWAAFNIIEVMSASKFTFKEESGMAHESAEDLFHFNVGGWHFSVPRSKLSQFPDSLLWKEASALTSSES
QRLFIDRDGSTFRHVHYYLYTSKLSFSSCAELNLLYEQALGLQLMPLLQTLDNLKEGKHHLRVRPADLPVAERASLNYWRTWKCISKPSE
FPIKSPAFTGLHDKAPLGLMDTPLLDTEEEVHYCFLPLDLVAKYPSLVTEDNLLWLAETVALIECECSEFRFIVNFLRSQKILLPDNFSN
IDVLEAEVEILEIPALTEAVRWYRMNMGGCSPTTCSPLSPGKGARTASLESVKPLYTMALGLLVKYPDSALGQLRIESTLDGSRLYITGN
GVLFQHVKNWLGTCRLPLTETISEVYELCAFLDKRDITYEPIKVALKTHLEPRTLAPMDVLNEWTAEITVYSPQQIIKVYVGSHWYATTL
QTLLKYPELLSNPQRVYWITYGQTLLIHGDGQMFRHILNFLRLGKLFLPSEFKEWPLFCQEVEEYHIPSLSEALAQCEAYKSWTQEKESE
NEEAFSIRRLHVVTEGPGSLVEFSRDTKETTAYMPVDFEDCSDRTPWNKAKGNLVRSNQMDEAEQYTRPIQVSLCRNAKRAGNPSTYSHC
RGLCTNPGHWGSHPESPPKKKCTTINLTQKSETKDPPATPMQKLISLVREWDMVNCKQWEFQPLTATRSSPLEEATLQLPLGSEAASQPS
TSAAWKAHSTASEKDPGPQAGAGAGAKDKGPEPTFKPYLPPKRAGTLKDWSKQRTKERESPAPEQPLPEASEVDSLGVILKVTHPPVVGS
DGFCMFFEDSIIYTTEMDNLRHTTPTASPQPQEVTFLSFSLSWEEMFYAQKCHCFLADIIMDSIRQKDPKAITAKVVSLANRLWTLHISP

--------------------------------------------------------------
>5277_5277_5_AP3D1-KCTD19_AP3D1_chr19_2138618_ENST00000345016_KCTD19_chr16_67354788_ENST00000304372_length(transcript)=3323nt_BP=424nt
GCCGCCATCTTGTCCGCCATTTGCAAGGGGCCCGGAGCGGGATCGCGGCACCTGCCGAGCGGGTCGCCGCCTCTGCCGCGGTCCTTGGAC
CCCGCCGCCGCCCTGGCCTGGGAGCTTGCCCCGCCGCAGCGGCCGGCAGCGCGGCGCTCCGCGGGCGGCAGGCACGGGCCCCGGGCCCCC
TCACGGCGCCCAGCCGCGGGCCTCCCGAGGCAAAAGCCCGTGGGCCGCCGCGATGGCCCTCAAGATGGTGAAGGGCAGCATCGACCGCAT
GTTCGACAAGAATCTGCAGGACTTGGTCCGCGGCATCCGTAACCACAAGGAGGACGAGGCAAAATACATATCTCAGTGCATTGATGAGAT
CAAGCAGGAGCTGAAGCAGGACAACATAGCGGTGAAGGCGAACGCGGTCTGCAAGCTGACGTATGAGGAGTCTGGCATGGCTCATGAATC
AGCAGAGGACTTGTTTCATTTCAACGTAGGGGGCTGGCATTTCTCAGTTCCCAGAAGCAAACTCTCTCAGTTTCCAGACTCCCTGCTGTG
GAAAGAGGCTTCAGCCTTGACCTCTTCAGAAAGCCAGAGGCTATTTATCGACAGAGATGGTTCCACATTTAGGCACGTGCACTATTACCT
CTACACCTCCAAACTCTCCTTCTCCAGTTGTGCAGAACTGAACTTGCTGTATGAGCAAGCATTGGGTTTGCAGCTGATGCCTTTGCTGCA
GACTCTAGATAACCTGAAGGAAGGGAAACACCATCTACGCGTACGGCCTGCAGACCTACCTGTTGCTGAGAGAGCATCTCTGAACTACTG
GCGTACATGGAAGTGTATTAGCAAACCCTCAGAATTTCCAATTAAAAGCCCAGCCTTTACAGGCCTACATGATAAGGCACCTCTGGGGCT
CATGGACACACCCCTGTTAGACACAGAAGAGGAGGTGCACTACTGCTTCCTGCCCCTAGACCTGGTGGCCAAATATCCCAGCCTAGTGAC
TGAAGACAACCTGCTGTGGCTGGCTGAGACGGTGGCCCTCATCGAGTGCGAGTGCAGCGAGTTCCGCTTCATTGTGAATTTTCTTCGCTC
ACAGAAGATTTTACTACCGGATAATTTCTCCAACATTGATGTATTAGAAGCAGAAGTGGAAATTCTGGAAATCCCTGCACTCACTGAAGC
CGTAAGGTGGTACCGGATGAACATGGGTGGCTGTTCCCCGACCACCTGTTCTCCCCTGAGCCCCGGGAAGGGGGCCCGCACAGCCAGCCT
GGAGTCCGTGAAACCGCTCTACACAATGGCCCTGGGTCTGCTGGTCAAGTACCCGGACTCTGCGCTGGGCCAGCTTCGCATCGAGAGCAC
GCTAGACGGAAGCCGACTGTACATCACAGGGAATGGCGTCCTCTTTCAGCACGTCAAGAACTGGCTGGGGACTTGCCGGCTGCCCCTGAC
AGAGACCATTTCCGAGGTATATGAGCTCTGTGCCTTCCTAGACAAAAGGGACATCACCTACGAGCCAATCAAAGTTGCTTTGAAGACTCA
TCTGGAGCCAAGGACTTTGGCACCCATGGATGTGCTCAATGAGTGGACGGCAGAGATCACTGTGTATTCCCCACAACAGATCATCAAAGT
GTATGTTGGAAGCCACTGGTACGCAACCACCCTGCAGACACTGCTGAAGTATCCAGAACTGCTGTCCAACCCTCAGAGAGTGTACTGGAT
CACATATGGACAAACCCTGCTCATCCACGGGGATGGCCAGATGTTCCGACACATTCTCAACTTCCTGAGACTTGGCAAACTGTTTTTACC
ATCTGAATTTAAGGAATGGCCCCTCTTCTGCCAGGAGGTGGAGGAATACCACATTCCATCCCTCTCAGAAGCCCTTGCACAATGTGAAGC
ATACAAGTCATGGACTCAGGAGAAAGAATCTGAAAATGAAGAAGCTTTTTCCATCAGGAGGCTGCATGTGGTGACAGAAGGGCCAGGGTC
ACTGGTGGAGTTCAGTAGAGACACTAAAGAAACCACAGCCTACATGCCTGTGGACTTCGAAGACTGCAGTGACAGGACTCCATGGAACAA
GGCTAAGGGAAACCTGGTCAGGTCCAACCAGATGGATGAGGCTGAGCAGTACACTCGGCCCATCCAGGTGTCCCTATGCCGAAATGCCAA
GAGGGCTGGCAACCCTAGCACATACTCACACTGCCGTGGCTTGTGTACCAATCCTGGACACTGGGGGAGCCACCCTGAGAGCCCCCCAAA
GAAGAAATGCACCACAATCAACCTCACACAGAAATCTGAAACCAAAGACCCTCCCGCCACTCCCATGCAAAAACTCATCTCCCTGGTGAG
AGAATGGGACATGGTCAATTGCAAACAGTGGGAATTCCAGCCACTGACAGCCACACGGAGCAGCCCCTTGGAGGAGGCCACCCTGCAGCT
CCCCTTGGGAAGCGAGGCTGCTTCCCAGCCCAGCACCTCAGCTGCCTGGAAAGCCCATTCCACAGCCTCAGAGAAGGATCCAGGACCACA
GGCAGGGGCTGGAGCTGGAGCGAAAGACAAGGGGCCAGAGCCAACCTTCAAGCCATACTTACCCCCAAAAAGAGCTGGCACCCTGAAGGA
CTGGAGCAAGCAGAGGACCAAGGAGAGAGAAAGCCCTGCCCCTGAGCAGCCTCTGCCCGAGGCCAGTGAGGTGGACAGCCTAGGGGTTAT
CCTCAAAGTGACTCACCCCCCCGTGGTGGGCAGCGATGGCTTCTGCATGTTCTTTGAGGACAGCATCATCTATACCACGGAGATGGACAA
CCTCAGGCACACAACACCCACAGCCAGTCCCCAGCCCCAAGAAGTGACTTTCCTGAGTTTCTCTCTGTCCTGGGAAGAGATGTTTTATGC
ACAGAAATGTCACTGCTTCCTGGCTGACATCATCATGGATTCCATCAGGCAAAAGGACCCCAAAGCCATCACAGCCAAGGTGGTCTCCCT
GGCCAATCGGCTGTGGACCCTGCACATCAGCCCCAAGCAGTTTGTGGTAGATTTGCTGGCCATCACCGGCTTCAAGGATGACCGGCACAC
CCAGGAGCGCCTGTACAGCTGGGTGGAGCTTACACTGCCCTTCGCCAGGAAATATGGCCGATGCATGGACCTGCTCATCCAGAGGGGCCT
GTCTAGGTCTGTCTCTTACTCCATCCTGGGAAAGTACCTACAAGAGGACTAGGGTGCCCAGAGATGCAGCCCCTCATGCCCCACCCGCCA

>5277_5277_5_AP3D1-KCTD19_AP3D1_chr19_2138618_ENST00000345016_KCTD19_chr16_67354788_ENST00000304372_length(amino acids)=1028AA_BP=103
MPRRSGRQRGAPRAAGTGPGPPHGAQPRASRGKSPWAAAMALKMVKGSIDRMFDKNLQDLVRGIRNHKEDEAKYISQCIDEIKQELKQDN
IAVKANAVCKLTYEESGMAHESAEDLFHFNVGGWHFSVPRSKLSQFPDSLLWKEASALTSSESQRLFIDRDGSTFRHVHYYLYTSKLSFS
SCAELNLLYEQALGLQLMPLLQTLDNLKEGKHHLRVRPADLPVAERASLNYWRTWKCISKPSEFPIKSPAFTGLHDKAPLGLMDTPLLDT
EEEVHYCFLPLDLVAKYPSLVTEDNLLWLAETVALIECECSEFRFIVNFLRSQKILLPDNFSNIDVLEAEVEILEIPALTEAVRWYRMNM
GGCSPTTCSPLSPGKGARTASLESVKPLYTMALGLLVKYPDSALGQLRIESTLDGSRLYITGNGVLFQHVKNWLGTCRLPLTETISEVYE
LCAFLDKRDITYEPIKVALKTHLEPRTLAPMDVLNEWTAEITVYSPQQIIKVYVGSHWYATTLQTLLKYPELLSNPQRVYWITYGQTLLI
HGDGQMFRHILNFLRLGKLFLPSEFKEWPLFCQEVEEYHIPSLSEALAQCEAYKSWTQEKESENEEAFSIRRLHVVTEGPGSLVEFSRDT
KETTAYMPVDFEDCSDRTPWNKAKGNLVRSNQMDEAEQYTRPIQVSLCRNAKRAGNPSTYSHCRGLCTNPGHWGSHPESPPKKKCTTINL
TQKSETKDPPATPMQKLISLVREWDMVNCKQWEFQPLTATRSSPLEEATLQLPLGSEAASQPSTSAAWKAHSTASEKDPGPQAGAGAGAK
DKGPEPTFKPYLPPKRAGTLKDWSKQRTKERESPAPEQPLPEASEVDSLGVILKVTHPPVVGSDGFCMFFEDSIIYTTEMDNLRHTTPTA
SPQPQEVTFLSFSLSWEEMFYAQKCHCFLADIIMDSIRQKDPKAITAKVVSLANRLWTLHISPKQFVVDLLAITGFKDDRHTQERLYSWV

--------------------------------------------------------------
>5277_5277_6_AP3D1-KCTD19_AP3D1_chr19_2138618_ENST00000350812_KCTD19_chr16_67354788_ENST00000304372_length(transcript)=3297nt_BP=398nt
GGGGCCCGGAGCGGGATCGCGGCACCTGCCGAGCGGGTCGCCGCCTCTGCCGCGGTCCTTGGACCCCGCCGCCGCCCTGGCCTGGGAGCT
TGCCCCGCCGCAGCGGCCGGCAGCGCGGCGCTCCGCGGGCGGCAGGCACGGGCCCCGGGCCCCCTCACGGCGCCCAGCCGCGGGCCTCCC
GAGGCAAAAGCCCGTGGGCCGCCGCGATGGCCCTCAAGATGGTGAAGGGCAGCATCGACCGCATGTTCGACAAGAATCTGCAGGACTTGG
TCCGCGGCATCCGTAACCACAAGGAGGACGAGGCAAAATACATATCTCAGTGCATTGATGAGATCAAGCAGGAGCTGAAGCAGGACAACA
TAGCGGTGAAGGCGAACGCGGTCTGCAAGCTGACGTATGAGGAGTCTGGCATGGCTCATGAATCAGCAGAGGACTTGTTTCATTTCAACG
TAGGGGGCTGGCATTTCTCAGTTCCCAGAAGCAAACTCTCTCAGTTTCCAGACTCCCTGCTGTGGAAAGAGGCTTCAGCCTTGACCTCTT
CAGAAAGCCAGAGGCTATTTATCGACAGAGATGGTTCCACATTTAGGCACGTGCACTATTACCTCTACACCTCCAAACTCTCCTTCTCCA
GTTGTGCAGAACTGAACTTGCTGTATGAGCAAGCATTGGGTTTGCAGCTGATGCCTTTGCTGCAGACTCTAGATAACCTGAAGGAAGGGA
AACACCATCTACGCGTACGGCCTGCAGACCTACCTGTTGCTGAGAGAGCATCTCTGAACTACTGGCGTACATGGAAGTGTATTAGCAAAC
CCTCAGAATTTCCAATTAAAAGCCCAGCCTTTACAGGCCTACATGATAAGGCACCTCTGGGGCTCATGGACACACCCCTGTTAGACACAG
AAGAGGAGGTGCACTACTGCTTCCTGCCCCTAGACCTGGTGGCCAAATATCCCAGCCTAGTGACTGAAGACAACCTGCTGTGGCTGGCTG
AGACGGTGGCCCTCATCGAGTGCGAGTGCAGCGAGTTCCGCTTCATTGTGAATTTTCTTCGCTCACAGAAGATTTTACTACCGGATAATT
TCTCCAACATTGATGTATTAGAAGCAGAAGTGGAAATTCTGGAAATCCCTGCACTCACTGAAGCCGTAAGGTGGTACCGGATGAACATGG
GTGGCTGTTCCCCGACCACCTGTTCTCCCCTGAGCCCCGGGAAGGGGGCCCGCACAGCCAGCCTGGAGTCCGTGAAACCGCTCTACACAA
TGGCCCTGGGTCTGCTGGTCAAGTACCCGGACTCTGCGCTGGGCCAGCTTCGCATCGAGAGCACGCTAGACGGAAGCCGACTGTACATCA
CAGGGAATGGCGTCCTCTTTCAGCACGTCAAGAACTGGCTGGGGACTTGCCGGCTGCCCCTGACAGAGACCATTTCCGAGGTATATGAGC
TCTGTGCCTTCCTAGACAAAAGGGACATCACCTACGAGCCAATCAAAGTTGCTTTGAAGACTCATCTGGAGCCAAGGACTTTGGCACCCA
TGGATGTGCTCAATGAGTGGACGGCAGAGATCACTGTGTATTCCCCACAACAGATCATCAAAGTGTATGTTGGAAGCCACTGGTACGCAA
CCACCCTGCAGACACTGCTGAAGTATCCAGAACTGCTGTCCAACCCTCAGAGAGTGTACTGGATCACATATGGACAAACCCTGCTCATCC
ACGGGGATGGCCAGATGTTCCGACACATTCTCAACTTCCTGAGACTTGGCAAACTGTTTTTACCATCTGAATTTAAGGAATGGCCCCTCT
TCTGCCAGGAGGTGGAGGAATACCACATTCCATCCCTCTCAGAAGCCCTTGCACAATGTGAAGCATACAAGTCATGGACTCAGGAGAAAG
AATCTGAAAATGAAGAAGCTTTTTCCATCAGGAGGCTGCATGTGGTGACAGAAGGGCCAGGGTCACTGGTGGAGTTCAGTAGAGACACTA
AAGAAACCACAGCCTACATGCCTGTGGACTTCGAAGACTGCAGTGACAGGACTCCATGGAACAAGGCTAAGGGAAACCTGGTCAGGTCCA
ACCAGATGGATGAGGCTGAGCAGTACACTCGGCCCATCCAGGTGTCCCTATGCCGAAATGCCAAGAGGGCTGGCAACCCTAGCACATACT
CACACTGCCGTGGCTTGTGTACCAATCCTGGACACTGGGGGAGCCACCCTGAGAGCCCCCCAAAGAAGAAATGCACCACAATCAACCTCA
CACAGAAATCTGAAACCAAAGACCCTCCCGCCACTCCCATGCAAAAACTCATCTCCCTGGTGAGAGAATGGGACATGGTCAATTGCAAAC
AGTGGGAATTCCAGCCACTGACAGCCACACGGAGCAGCCCCTTGGAGGAGGCCACCCTGCAGCTCCCCTTGGGAAGCGAGGCTGCTTCCC
AGCCCAGCACCTCAGCTGCCTGGAAAGCCCATTCCACAGCCTCAGAGAAGGATCCAGGACCACAGGCAGGGGCTGGAGCTGGAGCGAAAG
ACAAGGGGCCAGAGCCAACCTTCAAGCCATACTTACCCCCAAAAAGAGCTGGCACCCTGAAGGACTGGAGCAAGCAGAGGACCAAGGAGA
GAGAAAGCCCTGCCCCTGAGCAGCCTCTGCCCGAGGCCAGTGAGGTGGACAGCCTAGGGGTTATCCTCAAAGTGACTCACCCCCCCGTGG
TGGGCAGCGATGGCTTCTGCATGTTCTTTGAGGACAGCATCATCTATACCACGGAGATGGACAACCTCAGGCACACAACACCCACAGCCA
GTCCCCAGCCCCAAGAAGTGACTTTCCTGAGTTTCTCTCTGTCCTGGGAAGAGATGTTTTATGCACAGAAATGTCACTGCTTCCTGGCTG
ACATCATCATGGATTCCATCAGGCAAAAGGACCCCAAAGCCATCACAGCCAAGGTGGTCTCCCTGGCCAATCGGCTGTGGACCCTGCACA
TCAGCCCCAAGCAGTTTGTGGTAGATTTGCTGGCCATCACCGGCTTCAAGGATGACCGGCACACCCAGGAGCGCCTGTACAGCTGGGTGG
AGCTTACACTGCCCTTCGCCAGGAAATATGGCCGATGCATGGACCTGCTCATCCAGAGGGGCCTGTCTAGGTCTGTCTCTTACTCCATCC
TGGGAAAGTACCTACAAGAGGACTAGGGTGCCCAGAGATGCAGCCCCTCATGCCCCACCCGCCAAGTCTCATTTTAATTGGAGATAGCCC

>5277_5277_6_AP3D1-KCTD19_AP3D1_chr19_2138618_ENST00000350812_KCTD19_chr16_67354788_ENST00000304372_length(amino acids)=1028AA_BP=103
MPRRSGRQRGAPRAAGTGPGPPHGAQPRASRGKSPWAAAMALKMVKGSIDRMFDKNLQDLVRGIRNHKEDEAKYISQCIDEIKQELKQDN
IAVKANAVCKLTYEESGMAHESAEDLFHFNVGGWHFSVPRSKLSQFPDSLLWKEASALTSSESQRLFIDRDGSTFRHVHYYLYTSKLSFS
SCAELNLLYEQALGLQLMPLLQTLDNLKEGKHHLRVRPADLPVAERASLNYWRTWKCISKPSEFPIKSPAFTGLHDKAPLGLMDTPLLDT
EEEVHYCFLPLDLVAKYPSLVTEDNLLWLAETVALIECECSEFRFIVNFLRSQKILLPDNFSNIDVLEAEVEILEIPALTEAVRWYRMNM
GGCSPTTCSPLSPGKGARTASLESVKPLYTMALGLLVKYPDSALGQLRIESTLDGSRLYITGNGVLFQHVKNWLGTCRLPLTETISEVYE
LCAFLDKRDITYEPIKVALKTHLEPRTLAPMDVLNEWTAEITVYSPQQIIKVYVGSHWYATTLQTLLKYPELLSNPQRVYWITYGQTLLI
HGDGQMFRHILNFLRLGKLFLPSEFKEWPLFCQEVEEYHIPSLSEALAQCEAYKSWTQEKESENEEAFSIRRLHVVTEGPGSLVEFSRDT
KETTAYMPVDFEDCSDRTPWNKAKGNLVRSNQMDEAEQYTRPIQVSLCRNAKRAGNPSTYSHCRGLCTNPGHWGSHPESPPKKKCTTINL
TQKSETKDPPATPMQKLISLVREWDMVNCKQWEFQPLTATRSSPLEEATLQLPLGSEAASQPSTSAAWKAHSTASEKDPGPQAGAGAGAK
DKGPEPTFKPYLPPKRAGTLKDWSKQRTKERESPAPEQPLPEASEVDSLGVILKVTHPPVVGSDGFCMFFEDSIIYTTEMDNLRHTTPTA
SPQPQEVTFLSFSLSWEEMFYAQKCHCFLADIIMDSIRQKDPKAITAKVVSLANRLWTLHISPKQFVVDLLAITGFKDDRHTQERLYSWV

--------------------------------------------------------------
>5277_5277_7_AP3D1-KCTD19_AP3D1_chr19_2138618_ENST00000355272_KCTD19_chr16_67354788_ENST00000304372_length(transcript)=3298nt_BP=399nt
AGGGGCCCGGAGCGGGATCGCGGCACCTGCCGAGCGGGTCGCCGCCTCTGCCGCGGTCCTTGGACCCCGCCGCCGCCCTGGCCTGGGAGC
TTGCCCCGCCGCAGCGGCCGGCAGCGCGGCGCTCCGCGGGCGGCAGGCACGGGCCCCGGGCCCCCTCACGGCGCCCAGCCGCGGGCCTCC
CGAGGCAAAAGCCCGTGGGCCGCCGCGATGGCCCTCAAGATGGTGAAGGGCAGCATCGACCGCATGTTCGACAAGAATCTGCAGGACTTG
GTCCGCGGCATCCGTAACCACAAGGAGGACGAGGCAAAATACATATCTCAGTGCATTGATGAGATCAAGCAGGAGCTGAAGCAGGACAAC
ATAGCGGTGAAGGCGAACGCGGTCTGCAAGCTGACGTATGAGGAGTCTGGCATGGCTCATGAATCAGCAGAGGACTTGTTTCATTTCAAC
GTAGGGGGCTGGCATTTCTCAGTTCCCAGAAGCAAACTCTCTCAGTTTCCAGACTCCCTGCTGTGGAAAGAGGCTTCAGCCTTGACCTCT
TCAGAAAGCCAGAGGCTATTTATCGACAGAGATGGTTCCACATTTAGGCACGTGCACTATTACCTCTACACCTCCAAACTCTCCTTCTCC
AGTTGTGCAGAACTGAACTTGCTGTATGAGCAAGCATTGGGTTTGCAGCTGATGCCTTTGCTGCAGACTCTAGATAACCTGAAGGAAGGG
AAACACCATCTACGCGTACGGCCTGCAGACCTACCTGTTGCTGAGAGAGCATCTCTGAACTACTGGCGTACATGGAAGTGTATTAGCAAA
CCCTCAGAATTTCCAATTAAAAGCCCAGCCTTTACAGGCCTACATGATAAGGCACCTCTGGGGCTCATGGACACACCCCTGTTAGACACA
GAAGAGGAGGTGCACTACTGCTTCCTGCCCCTAGACCTGGTGGCCAAATATCCCAGCCTAGTGACTGAAGACAACCTGCTGTGGCTGGCT
GAGACGGTGGCCCTCATCGAGTGCGAGTGCAGCGAGTTCCGCTTCATTGTGAATTTTCTTCGCTCACAGAAGATTTTACTACCGGATAAT
TTCTCCAACATTGATGTATTAGAAGCAGAAGTGGAAATTCTGGAAATCCCTGCACTCACTGAAGCCGTAAGGTGGTACCGGATGAACATG
GGTGGCTGTTCCCCGACCACCTGTTCTCCCCTGAGCCCCGGGAAGGGGGCCCGCACAGCCAGCCTGGAGTCCGTGAAACCGCTCTACACA
ATGGCCCTGGGTCTGCTGGTCAAGTACCCGGACTCTGCGCTGGGCCAGCTTCGCATCGAGAGCACGCTAGACGGAAGCCGACTGTACATC
ACAGGGAATGGCGTCCTCTTTCAGCACGTCAAGAACTGGCTGGGGACTTGCCGGCTGCCCCTGACAGAGACCATTTCCGAGGTATATGAG
CTCTGTGCCTTCCTAGACAAAAGGGACATCACCTACGAGCCAATCAAAGTTGCTTTGAAGACTCATCTGGAGCCAAGGACTTTGGCACCC
ATGGATGTGCTCAATGAGTGGACGGCAGAGATCACTGTGTATTCCCCACAACAGATCATCAAAGTGTATGTTGGAAGCCACTGGTACGCA
ACCACCCTGCAGACACTGCTGAAGTATCCAGAACTGCTGTCCAACCCTCAGAGAGTGTACTGGATCACATATGGACAAACCCTGCTCATC
CACGGGGATGGCCAGATGTTCCGACACATTCTCAACTTCCTGAGACTTGGCAAACTGTTTTTACCATCTGAATTTAAGGAATGGCCCCTC
TTCTGCCAGGAGGTGGAGGAATACCACATTCCATCCCTCTCAGAAGCCCTTGCACAATGTGAAGCATACAAGTCATGGACTCAGGAGAAA
GAATCTGAAAATGAAGAAGCTTTTTCCATCAGGAGGCTGCATGTGGTGACAGAAGGGCCAGGGTCACTGGTGGAGTTCAGTAGAGACACT
AAAGAAACCACAGCCTACATGCCTGTGGACTTCGAAGACTGCAGTGACAGGACTCCATGGAACAAGGCTAAGGGAAACCTGGTCAGGTCC
AACCAGATGGATGAGGCTGAGCAGTACACTCGGCCCATCCAGGTGTCCCTATGCCGAAATGCCAAGAGGGCTGGCAACCCTAGCACATAC
TCACACTGCCGTGGCTTGTGTACCAATCCTGGACACTGGGGGAGCCACCCTGAGAGCCCCCCAAAGAAGAAATGCACCACAATCAACCTC
ACACAGAAATCTGAAACCAAAGACCCTCCCGCCACTCCCATGCAAAAACTCATCTCCCTGGTGAGAGAATGGGACATGGTCAATTGCAAA
CAGTGGGAATTCCAGCCACTGACAGCCACACGGAGCAGCCCCTTGGAGGAGGCCACCCTGCAGCTCCCCTTGGGAAGCGAGGCTGCTTCC
CAGCCCAGCACCTCAGCTGCCTGGAAAGCCCATTCCACAGCCTCAGAGAAGGATCCAGGACCACAGGCAGGGGCTGGAGCTGGAGCGAAA
GACAAGGGGCCAGAGCCAACCTTCAAGCCATACTTACCCCCAAAAAGAGCTGGCACCCTGAAGGACTGGAGCAAGCAGAGGACCAAGGAG
AGAGAAAGCCCTGCCCCTGAGCAGCCTCTGCCCGAGGCCAGTGAGGTGGACAGCCTAGGGGTTATCCTCAAAGTGACTCACCCCCCCGTG
GTGGGCAGCGATGGCTTCTGCATGTTCTTTGAGGACAGCATCATCTATACCACGGAGATGGACAACCTCAGGCACACAACACCCACAGCC
AGTCCCCAGCCCCAAGAAGTGACTTTCCTGAGTTTCTCTCTGTCCTGGGAAGAGATGTTTTATGCACAGAAATGTCACTGCTTCCTGGCT
GACATCATCATGGATTCCATCAGGCAAAAGGACCCCAAAGCCATCACAGCCAAGGTGGTCTCCCTGGCCAATCGGCTGTGGACCCTGCAC
ATCAGCCCCAAGCAGTTTGTGGTAGATTTGCTGGCCATCACCGGCTTCAAGGATGACCGGCACACCCAGGAGCGCCTGTACAGCTGGGTG
GAGCTTACACTGCCCTTCGCCAGGAAATATGGCCGATGCATGGACCTGCTCATCCAGAGGGGCCTGTCTAGGTCTGTCTCTTACTCCATC
CTGGGAAAGTACCTACAAGAGGACTAGGGTGCCCAGAGATGCAGCCCCTCATGCCCCACCCGCCAAGTCTCATTTTAATTGGAGATAGCC

>5277_5277_7_AP3D1-KCTD19_AP3D1_chr19_2138618_ENST00000355272_KCTD19_chr16_67354788_ENST00000304372_length(amino acids)=1028AA_BP=103
MPRRSGRQRGAPRAAGTGPGPPHGAQPRASRGKSPWAAAMALKMVKGSIDRMFDKNLQDLVRGIRNHKEDEAKYISQCIDEIKQELKQDN
IAVKANAVCKLTYEESGMAHESAEDLFHFNVGGWHFSVPRSKLSQFPDSLLWKEASALTSSESQRLFIDRDGSTFRHVHYYLYTSKLSFS
SCAELNLLYEQALGLQLMPLLQTLDNLKEGKHHLRVRPADLPVAERASLNYWRTWKCISKPSEFPIKSPAFTGLHDKAPLGLMDTPLLDT
EEEVHYCFLPLDLVAKYPSLVTEDNLLWLAETVALIECECSEFRFIVNFLRSQKILLPDNFSNIDVLEAEVEILEIPALTEAVRWYRMNM
GGCSPTTCSPLSPGKGARTASLESVKPLYTMALGLLVKYPDSALGQLRIESTLDGSRLYITGNGVLFQHVKNWLGTCRLPLTETISEVYE
LCAFLDKRDITYEPIKVALKTHLEPRTLAPMDVLNEWTAEITVYSPQQIIKVYVGSHWYATTLQTLLKYPELLSNPQRVYWITYGQTLLI
HGDGQMFRHILNFLRLGKLFLPSEFKEWPLFCQEVEEYHIPSLSEALAQCEAYKSWTQEKESENEEAFSIRRLHVVTEGPGSLVEFSRDT
KETTAYMPVDFEDCSDRTPWNKAKGNLVRSNQMDEAEQYTRPIQVSLCRNAKRAGNPSTYSHCRGLCTNPGHWGSHPESPPKKKCTTINL
TQKSETKDPPATPMQKLISLVREWDMVNCKQWEFQPLTATRSSPLEEATLQLPLGSEAASQPSTSAAWKAHSTASEKDPGPQAGAGAGAK
DKGPEPTFKPYLPPKRAGTLKDWSKQRTKERESPAPEQPLPEASEVDSLGVILKVTHPPVVGSDGFCMFFEDSIIYTTEMDNLRHTTPTA
SPQPQEVTFLSFSLSWEEMFYAQKCHCFLADIIMDSIRQKDPKAITAKVVSLANRLWTLHISPKQFVVDLLAITGFKDDRHTQERLYSWV

--------------------------------------------------------------
>5277_5277_8_AP3D1-KCTD19_AP3D1_chr19_2138618_ENST00000356926_KCTD19_chr16_67354788_ENST00000304372_length(transcript)=3314nt_BP=415nt
TTGTCCGCCATTTGCAAGGGGCCCGGAGCGGGATCGCGGCACCTGCCGAGCGGGTCGCCGCCTCTGCCGCGGTCCTTGGACCCCGCCGCC
GCCCTGGCCTGGGAGCTTGCCCCGCCGCAGCGGCCGGCAGCGCGGCGCTCCGCGGGCGGCAGGCACGGGCCCCGGGCCCCCTCACGGCGC
CCAGCCGCGGGCCTCCCGAGGCAAAAGCCCGTGGGCCGCCGCGATGGCCCTCAAGATGGTGAAGGGCAGCATCGACCGCATGTTCGACAA
GAATCTGCAGGACTTGGTCCGCGGCATCCGTAACCACAAGGAGGACGAGGCAAAATACATATCTCAGTGCATTGATGAGATCAAGCAGGA
GCTGAAGCAGGACAACATAGCGGTGAAGGCGAACGCGGTCTGCAAGCTGACGTATGAGGAGTCTGGCATGGCTCATGAATCAGCAGAGGA
CTTGTTTCATTTCAACGTAGGGGGCTGGCATTTCTCAGTTCCCAGAAGCAAACTCTCTCAGTTTCCAGACTCCCTGCTGTGGAAAGAGGC
TTCAGCCTTGACCTCTTCAGAAAGCCAGAGGCTATTTATCGACAGAGATGGTTCCACATTTAGGCACGTGCACTATTACCTCTACACCTC
CAAACTCTCCTTCTCCAGTTGTGCAGAACTGAACTTGCTGTATGAGCAAGCATTGGGTTTGCAGCTGATGCCTTTGCTGCAGACTCTAGA
TAACCTGAAGGAAGGGAAACACCATCTACGCGTACGGCCTGCAGACCTACCTGTTGCTGAGAGAGCATCTCTGAACTACTGGCGTACATG
GAAGTGTATTAGCAAACCCTCAGAATTTCCAATTAAAAGCCCAGCCTTTACAGGCCTACATGATAAGGCACCTCTGGGGCTCATGGACAC
ACCCCTGTTAGACACAGAAGAGGAGGTGCACTACTGCTTCCTGCCCCTAGACCTGGTGGCCAAATATCCCAGCCTAGTGACTGAAGACAA
CCTGCTGTGGCTGGCTGAGACGGTGGCCCTCATCGAGTGCGAGTGCAGCGAGTTCCGCTTCATTGTGAATTTTCTTCGCTCACAGAAGAT
TTTACTACCGGATAATTTCTCCAACATTGATGTATTAGAAGCAGAAGTGGAAATTCTGGAAATCCCTGCACTCACTGAAGCCGTAAGGTG
GTACCGGATGAACATGGGTGGCTGTTCCCCGACCACCTGTTCTCCCCTGAGCCCCGGGAAGGGGGCCCGCACAGCCAGCCTGGAGTCCGT
GAAACCGCTCTACACAATGGCCCTGGGTCTGCTGGTCAAGTACCCGGACTCTGCGCTGGGCCAGCTTCGCATCGAGAGCACGCTAGACGG
AAGCCGACTGTACATCACAGGGAATGGCGTCCTCTTTCAGCACGTCAAGAACTGGCTGGGGACTTGCCGGCTGCCCCTGACAGAGACCAT
TTCCGAGGTATATGAGCTCTGTGCCTTCCTAGACAAAAGGGACATCACCTACGAGCCAATCAAAGTTGCTTTGAAGACTCATCTGGAGCC
AAGGACTTTGGCACCCATGGATGTGCTCAATGAGTGGACGGCAGAGATCACTGTGTATTCCCCACAACAGATCATCAAAGTGTATGTTGG
AAGCCACTGGTACGCAACCACCCTGCAGACACTGCTGAAGTATCCAGAACTGCTGTCCAACCCTCAGAGAGTGTACTGGATCACATATGG
ACAAACCCTGCTCATCCACGGGGATGGCCAGATGTTCCGACACATTCTCAACTTCCTGAGACTTGGCAAACTGTTTTTACCATCTGAATT
TAAGGAATGGCCCCTCTTCTGCCAGGAGGTGGAGGAATACCACATTCCATCCCTCTCAGAAGCCCTTGCACAATGTGAAGCATACAAGTC
ATGGACTCAGGAGAAAGAATCTGAAAATGAAGAAGCTTTTTCCATCAGGAGGCTGCATGTGGTGACAGAAGGGCCAGGGTCACTGGTGGA
GTTCAGTAGAGACACTAAAGAAACCACAGCCTACATGCCTGTGGACTTCGAAGACTGCAGTGACAGGACTCCATGGAACAAGGCTAAGGG
AAACCTGGTCAGGTCCAACCAGATGGATGAGGCTGAGCAGTACACTCGGCCCATCCAGGTGTCCCTATGCCGAAATGCCAAGAGGGCTGG
CAACCCTAGCACATACTCACACTGCCGTGGCTTGTGTACCAATCCTGGACACTGGGGGAGCCACCCTGAGAGCCCCCCAAAGAAGAAATG
CACCACAATCAACCTCACACAGAAATCTGAAACCAAAGACCCTCCCGCCACTCCCATGCAAAAACTCATCTCCCTGGTGAGAGAATGGGA
CATGGTCAATTGCAAACAGTGGGAATTCCAGCCACTGACAGCCACACGGAGCAGCCCCTTGGAGGAGGCCACCCTGCAGCTCCCCTTGGG
AAGCGAGGCTGCTTCCCAGCCCAGCACCTCAGCTGCCTGGAAAGCCCATTCCACAGCCTCAGAGAAGGATCCAGGACCACAGGCAGGGGC
TGGAGCTGGAGCGAAAGACAAGGGGCCAGAGCCAACCTTCAAGCCATACTTACCCCCAAAAAGAGCTGGCACCCTGAAGGACTGGAGCAA
GCAGAGGACCAAGGAGAGAGAAAGCCCTGCCCCTGAGCAGCCTCTGCCCGAGGCCAGTGAGGTGGACAGCCTAGGGGTTATCCTCAAAGT
GACTCACCCCCCCGTGGTGGGCAGCGATGGCTTCTGCATGTTCTTTGAGGACAGCATCATCTATACCACGGAGATGGACAACCTCAGGCA
CACAACACCCACAGCCAGTCCCCAGCCCCAAGAAGTGACTTTCCTGAGTTTCTCTCTGTCCTGGGAAGAGATGTTTTATGCACAGAAATG
TCACTGCTTCCTGGCTGACATCATCATGGATTCCATCAGGCAAAAGGACCCCAAAGCCATCACAGCCAAGGTGGTCTCCCTGGCCAATCG
GCTGTGGACCCTGCACATCAGCCCCAAGCAGTTTGTGGTAGATTTGCTGGCCATCACCGGCTTCAAGGATGACCGGCACACCCAGGAGCG
CCTGTACAGCTGGGTGGAGCTTACACTGCCCTTCGCCAGGAAATATGGCCGATGCATGGACCTGCTCATCCAGAGGGGCCTGTCTAGGTC
TGTCTCTTACTCCATCCTGGGAAAGTACCTACAAGAGGACTAGGGTGCCCAGAGATGCAGCCCCTCATGCCCCACCCGCCAAGTCTCATT

>5277_5277_8_AP3D1-KCTD19_AP3D1_chr19_2138618_ENST00000356926_KCTD19_chr16_67354788_ENST00000304372_length(amino acids)=1028AA_BP=103
MPRRSGRQRGAPRAAGTGPGPPHGAQPRASRGKSPWAAAMALKMVKGSIDRMFDKNLQDLVRGIRNHKEDEAKYISQCIDEIKQELKQDN
IAVKANAVCKLTYEESGMAHESAEDLFHFNVGGWHFSVPRSKLSQFPDSLLWKEASALTSSESQRLFIDRDGSTFRHVHYYLYTSKLSFS
SCAELNLLYEQALGLQLMPLLQTLDNLKEGKHHLRVRPADLPVAERASLNYWRTWKCISKPSEFPIKSPAFTGLHDKAPLGLMDTPLLDT
EEEVHYCFLPLDLVAKYPSLVTEDNLLWLAETVALIECECSEFRFIVNFLRSQKILLPDNFSNIDVLEAEVEILEIPALTEAVRWYRMNM
GGCSPTTCSPLSPGKGARTASLESVKPLYTMALGLLVKYPDSALGQLRIESTLDGSRLYITGNGVLFQHVKNWLGTCRLPLTETISEVYE
LCAFLDKRDITYEPIKVALKTHLEPRTLAPMDVLNEWTAEITVYSPQQIIKVYVGSHWYATTLQTLLKYPELLSNPQRVYWITYGQTLLI
HGDGQMFRHILNFLRLGKLFLPSEFKEWPLFCQEVEEYHIPSLSEALAQCEAYKSWTQEKESENEEAFSIRRLHVVTEGPGSLVEFSRDT
KETTAYMPVDFEDCSDRTPWNKAKGNLVRSNQMDEAEQYTRPIQVSLCRNAKRAGNPSTYSHCRGLCTNPGHWGSHPESPPKKKCTTINL
TQKSETKDPPATPMQKLISLVREWDMVNCKQWEFQPLTATRSSPLEEATLQLPLGSEAASQPSTSAAWKAHSTASEKDPGPQAGAGAGAK
DKGPEPTFKPYLPPKRAGTLKDWSKQRTKERESPAPEQPLPEASEVDSLGVILKVTHPPVVGSDGFCMFFEDSIIYTTEMDNLRHTTPTA
SPQPQEVTFLSFSLSWEEMFYAQKCHCFLADIIMDSIRQKDPKAITAKVVSLANRLWTLHISPKQFVVDLLAITGFKDDRHTQERLYSWV

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Fusion Gene PPI Analysis for AP3D1-KCTD19


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for AP3D1-KCTD19


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for AP3D1-KCTD19


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneAP3D1C0001916Albinism1GENOMICS_ENGLAND
HgeneAP3D1C0005818Blood Platelet Disorders1GENOMICS_ENGLAND
HgeneAP3D1C0027947Neutropenia1GENOMICS_ENGLAND
HgeneAP3D1C0036572Seizures1GENOMICS_ENGLAND
HgeneAP3D1C0078917Albinism, Ocular1ORPHANET
HgeneAP3D1C0079504Hermanski-Pudlak Syndrome1CTD_human;GENOMICS_ENGLAND
HgeneAP3D1C4310746HERMANSKY-PUDLAK SYNDROME 101GENOMICS_ENGLAND