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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:CLDN10-TTC12 (FusionGDB2 ID:HG9071TG54970)

Fusion Gene Summary for CLDN10-TTC12

Fusion gene summary

Fusion gene information	Fusion gene name: CLDN10-TTC12
	Fusion gene ID: hg9071tg54970
		Hgene	Tgene
	Gene symbol	CLDN10	TTC12
	Gene ID	9071	54970
	Gene name	claudin 10	tetratricopeptide repeat domain 12
	Synonyms	CPETRL3\|HELIX\|OSP-L\|OSPL	CILD45\|TPARM
	Cytomap	('CLDN10')('TTC12') 13q32.1	11q23.2
	Type of gene	protein-coding	protein-coding
	Description	claudin-10OSP-like proteinoligodendrocyte-specific protein-like	tetratricopeptide repeat protein 12TPR repeat protein 12
	Modification date	20200329	20200314
	UniProtAcc	P78369	.
	Ensembl transtripts involved in fusion gene	ENST00000299339, ENST00000376855, ENST00000376873,
Fusion gene scores	* DoF score	3 X 3 X 2=18	6 X 7 X 4=168
	# samples	3	7
	** MAII score	log2(3/18*10)=0.736965594166206 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0	log2(7/168*10)=-1.26303440583379 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: CLDN10 [Title/Abstract] AND TTC12 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	CLDN10(96229592)-TTC12(113220795), # samples:1 CLDN10(96212717)-TTC12(113220795), # samples:1
Anticipated loss of major functional domain due to fusion event.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner

Gene

GO ID

GO term

PubMed ID

Fusion gene breakpoints across CLDN10 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across TTC12 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	HNSC	TCGA-CR-6467-01A	CLDN10	chr13	96212717	-	TTC12	chr11	113220795	+
ChimerDB4	HNSC	TCGA-CR-6467-01A	CLDN10	chr13	96229592	+	TTC12	chr11	113220795	+

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Fusion Gene ORF analysis for CLDN10-TTC12

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5CDS-3UTR	ENST00000299339	ENST00000478125	CLDN10	chr13	96212717	-	TTC12	chr11	113220795	+
5CDS-3UTR	ENST00000299339	ENST00000478125	CLDN10	chr13	96229592	+	TTC12	chr11	113220795	+
5CDS-3UTR	ENST00000376855	ENST00000478125	CLDN10	chr13	96212717	-	TTC12	chr11	113220795	+
5CDS-3UTR	ENST00000376873	ENST00000478125	CLDN10	chr13	96212717	-	TTC12	chr11	113220795	+
5CDS-3UTR	ENST00000376873	ENST00000478125	CLDN10	chr13	96229592	+	TTC12	chr11	113220795	+
Frame-shift	ENST00000376855	ENST00000314756	CLDN10	chr13	96212717	-	TTC12	chr11	113220795	+
Frame-shift	ENST00000376855	ENST00000393020	CLDN10	chr13	96212717	-	TTC12	chr11	113220795	+
Frame-shift	ENST00000376855	ENST00000483239	CLDN10	chr13	96212717	-	TTC12	chr11	113220795	+
Frame-shift	ENST00000376855	ENST00000529221	CLDN10	chr13	96212717	-	TTC12	chr11	113220795	+
In-frame	ENST00000299339	ENST00000314756	CLDN10	chr13	96212717	-	TTC12	chr11	113220795	+
In-frame	ENST00000299339	ENST00000314756	CLDN10	chr13	96229592	+	TTC12	chr11	113220795	+
In-frame	ENST00000299339	ENST00000393020	CLDN10	chr13	96212717	-	TTC12	chr11	113220795	+
In-frame	ENST00000299339	ENST00000393020	CLDN10	chr13	96229592	+	TTC12	chr11	113220795	+
In-frame	ENST00000299339	ENST00000483239	CLDN10	chr13	96212717	-	TTC12	chr11	113220795	+
In-frame	ENST00000299339	ENST00000483239	CLDN10	chr13	96229592	+	TTC12	chr11	113220795	+
In-frame	ENST00000299339	ENST00000529221	CLDN10	chr13	96212717	-	TTC12	chr11	113220795	+
In-frame	ENST00000299339	ENST00000529221	CLDN10	chr13	96229592	+	TTC12	chr11	113220795	+
In-frame	ENST00000376873	ENST00000314756	CLDN10	chr13	96212717	-	TTC12	chr11	113220795	+
In-frame	ENST00000376873	ENST00000314756	CLDN10	chr13	96229592	+	TTC12	chr11	113220795	+
In-frame	ENST00000376873	ENST00000393020	CLDN10	chr13	96212717	-	TTC12	chr11	113220795	+
In-frame	ENST00000376873	ENST00000393020	CLDN10	chr13	96229592	+	TTC12	chr11	113220795	+
In-frame	ENST00000376873	ENST00000483239	CLDN10	chr13	96212717	-	TTC12	chr11	113220795	+
In-frame	ENST00000376873	ENST00000483239	CLDN10	chr13	96229592	+	TTC12	chr11	113220795	+
In-frame	ENST00000376873	ENST00000529221	CLDN10	chr13	96212717	-	TTC12	chr11	113220795	+
In-frame	ENST00000376873	ENST00000529221	CLDN10	chr13	96229592	+	TTC12	chr11	113220795	+
intron-3CDS	ENST00000376855	ENST00000314756	CLDN10	chr13	96229592	+	TTC12	chr11	113220795	+
intron-3CDS	ENST00000376855	ENST00000393020	CLDN10	chr13	96229592	+	TTC12	chr11	113220795	+
intron-3CDS	ENST00000376855	ENST00000483239	CLDN10	chr13	96229592	+	TTC12	chr11	113220795	+
intron-3CDS	ENST00000376855	ENST00000529221	CLDN10	chr13	96229592	+	TTC12	chr11	113220795	+
intron-3UTR	ENST00000376855	ENST00000478125	CLDN10	chr13	96229592	+	TTC12	chr11	113220795	+

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000376873	CLDN10	chr13	96229592	+	ENST00000393020	TTC12	chr11	113220795	+	1778	796	146	1651	501
ENST00000376873	CLDN10	chr13	96229592	+	ENST00000529221	TTC12	chr11	113220795	+	1852	796	146	1759	537
ENST00000376873	CLDN10	chr13	96229592	+	ENST00000314756	TTC12	chr11	113220795	+	1841	796	146	1840	565
ENST00000376873	CLDN10	chr13	96229592	+	ENST00000483239	TTC12	chr11	113220795	+	1847	796	146	1759	537
ENST00000299339	CLDN10	chr13	96229592	+	ENST00000393020	TTC12	chr11	113220795	+	1583	601	29	1456	475
ENST00000299339	CLDN10	chr13	96229592	+	ENST00000529221	TTC12	chr11	113220795	+	1657	601	29	1564	511
ENST00000299339	CLDN10	chr13	96229592	+	ENST00000314756	TTC12	chr11	113220795	+	1646	601	29	1645	539
ENST00000299339	CLDN10	chr13	96229592	+	ENST00000483239	TTC12	chr11	113220795	+	1652	601	29	1564	511
ENST00000376873	CLDN10	chr13	96212717	-	ENST00000393020	TTC12	chr11	113220795	+	1670	688	146	1543	465
ENST00000376873	CLDN10	chr13	96212717	-	ENST00000529221	TTC12	chr11	113220795	+	1744	688	146	1651	501
ENST00000376873	CLDN10	chr13	96212717	-	ENST00000314756	TTC12	chr11	113220795	+	1733	688	146	1732	529
ENST00000376873	CLDN10	chr13	96212717	-	ENST00000483239	TTC12	chr11	113220795	+	1739	688	146	1651	501
ENST00000299339	CLDN10	chr13	96212717	-	ENST00000393020	TTC12	chr11	113220795	+	1475	493	29	1348	439
ENST00000299339	CLDN10	chr13	96212717	-	ENST00000529221	TTC12	chr11	113220795	+	1549	493	29	1456	475
ENST00000299339	CLDN10	chr13	96212717	-	ENST00000314756	TTC12	chr11	113220795	+	1538	493	29	1537	503
ENST00000299339	CLDN10	chr13	96212717	-	ENST00000483239	TTC12	chr11	113220795	+	1544	493	29	1456	475

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000376873	ENST00000393020	CLDN10	chr13	96229592	+	TTC12	chr11	113220795	+	0.003425552	0.9965745
ENST00000376873	ENST00000529221	CLDN10	chr13	96229592	+	TTC12	chr11	113220795	+	0.000836182	0.99916387
ENST00000376873	ENST00000314756	CLDN10	chr13	96229592	+	TTC12	chr11	113220795	+	0.002129421	0.99787056
ENST00000376873	ENST00000483239	CLDN10	chr13	96229592	+	TTC12	chr11	113220795	+	0.000836204	0.99916387
ENST00000299339	ENST00000393020	CLDN10	chr13	96229592	+	TTC12	chr11	113220795	+	0.007704019	0.9922959
ENST00000299339	ENST00000529221	CLDN10	chr13	96229592	+	TTC12	chr11	113220795	+	0.004123671	0.9958763
ENST00000299339	ENST00000314756	CLDN10	chr13	96229592	+	TTC12	chr11	113220795	+	0.008208517	0.9917915
ENST00000299339	ENST00000483239	CLDN10	chr13	96229592	+	TTC12	chr11	113220795	+	0.004091987	0.995908
ENST00000376873	ENST00000393020	CLDN10	chr13	96212717	-	TTC12	chr11	113220795	+	0.005396522	0.99460346
ENST00000376873	ENST00000529221	CLDN10	chr13	96212717	-	TTC12	chr11	113220795	+	0.001271727	0.9987282
ENST00000376873	ENST00000314756	CLDN10	chr13	96212717	-	TTC12	chr11	113220795	+	0.002766559	0.99723345
ENST00000376873	ENST00000483239	CLDN10	chr13	96212717	-	TTC12	chr11	113220795	+	0.001275301	0.99872464
ENST00000299339	ENST00000393020	CLDN10	chr13	96212717	-	TTC12	chr11	113220795	+	0.008136307	0.9918637
ENST00000299339	ENST00000529221	CLDN10	chr13	96212717	-	TTC12	chr11	113220795	+	0.00412277	0.99587727
ENST00000299339	ENST00000314756	CLDN10	chr13	96212717	-	TTC12	chr11	113220795	+	0.00740258	0.99259746
ENST00000299339	ENST00000483239	CLDN10	chr13	96212717	-	TTC12	chr11	113220795	+	0.004099388	0.9959006

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Fusion Genomic Features for CLDN10-TTC12

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	1-p	p (fusion gene breakpoint)
CLDN10	chr13	96229592	+	TTC12	chr11	113220794	+	0.3126433	0.68735665
CLDN10	chr13	96229592	+	TTC12	chr11	113220794	+	0.3126433	0.68735665

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for CLDN10-TTC12

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr13:96229592/chr11:113220795)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
CLDN10 P78369	.
FUNCTION: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Involved in the regulation of paracellular epithelia permeability to ions in multiple organs. It acts as a paracellular ion channel probably forming permselective pores; isoform 1 appears to create pores preferentially permeable to cations and isoform 2 for anions. In sweat glands and in the thick ascending limb (TAL) of Henle's loop in kidney, it controls paracellular sodium permeability which is essential for proper sweat production and renal function (PubMed:19383724, PubMed:28771254, PubMed:28686597). {ECO:0000269\|PubMed:19383724, ECO:0000269\|PubMed:28686597, ECO:0000269\|PubMed:28771254}.	FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

CLDN10

chr13:96212717

chr11:113220795

ENST00000299339

102_115

154

229.0

Topological domain

Cytoplasmic

Hgene

CLDN10

chr13:96212717

chr11:113220795

ENST00000299339

22_80

154

229.0

Topological domain

Extracellular

Hgene

CLDN10

chr13:96212717

chr11:113220795

ENST00000376873

102_115

152

227.0

Topological domain

Cytoplasmic

Hgene

CLDN10

chr13:96212717

chr11:113220795

ENST00000376873

22_80

152

227.0

Topological domain

Extracellular

Hgene

CLDN10

chr13:96229592

chr11:113220795

ENST00000299339

102_115

190

229.0

Topological domain

Cytoplasmic

Hgene

CLDN10

chr13:96229592

chr11:113220795

ENST00000299339

137_160

190

229.0

Topological domain

Extracellular

Hgene

CLDN10

chr13:96229592

chr11:113220795

ENST00000299339

22_80

190

229.0

Topological domain

Extracellular

Hgene

CLDN10

chr13:96229592

chr11:113220795

ENST00000376873

102_115

188

227.0

Topological domain

Cytoplasmic

Hgene

CLDN10

chr13:96229592

chr11:113220795

ENST00000376873

137_160

188

227.0

Topological domain

Extracellular

Hgene

CLDN10

chr13:96229592

chr11:113220795

ENST00000376873

22_80

188

227.0

Topological domain

Extracellular

Hgene

CLDN10

chr13:96212717

chr11:113220795

ENST00000299339

116_136

154

229.0

Transmembrane

Helical

Hgene

CLDN10

chr13:96212717

chr11:113220795

ENST00000299339

1_21

154

229.0

Transmembrane

Helical

Hgene

CLDN10

chr13:96212717

chr11:113220795

ENST00000299339

81_101

154

229.0

Transmembrane

Helical

Hgene

CLDN10

chr13:96212717

chr11:113220795

ENST00000376873

116_136

152

227.0

Transmembrane

Helical

Hgene

CLDN10

chr13:96212717

chr11:113220795

ENST00000376873

1_21

152

227.0

Transmembrane

Helical

Hgene

CLDN10

chr13:96212717

chr11:113220795

ENST00000376873

81_101

152

227.0

Transmembrane

Helical

Hgene

CLDN10

chr13:96229592

chr11:113220795

ENST00000299339

116_136

190

229.0

Transmembrane

Helical

Hgene

CLDN10

chr13:96229592

chr11:113220795

ENST00000299339

161_181

190

229.0

Transmembrane

Helical

Hgene

CLDN10

chr13:96229592

chr11:113220795

ENST00000299339

1_21

190

229.0

Transmembrane

Helical

Hgene

CLDN10

chr13:96229592

chr11:113220795

ENST00000299339

81_101

190

229.0

Transmembrane

Helical

Hgene

CLDN10

chr13:96229592

chr11:113220795

ENST00000376873

116_136

188

227.0

Transmembrane

Helical

Hgene

CLDN10

chr13:96229592

chr11:113220795

ENST00000376873

161_181

188

227.0

Transmembrane

Helical

Hgene

CLDN10

chr13:96229592

chr11:113220795

ENST00000376873

1_21

188

227.0

Transmembrane

Helical

Hgene

CLDN10

chr13:96229592

chr11:113220795

ENST00000376873

81_101

188

227.0

Transmembrane

Helical

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

CLDN10

chr13:96212717

chr11:113220795

ENST00000299339

137_160

154

229.0

Topological domain

Extracellular

Hgene

CLDN10

chr13:96212717

chr11:113220795

ENST00000299339

182_228

154

229.0

Topological domain

Cytoplasmic

Hgene

CLDN10

chr13:96212717

chr11:113220795

ENST00000376873

137_160

152

227.0

Topological domain

Extracellular

Hgene

CLDN10

chr13:96212717

chr11:113220795

ENST00000376873

182_228

152

227.0

Topological domain

Cytoplasmic

Hgene

CLDN10

chr13:96229592

chr11:113220795

ENST00000299339

182_228

190

229.0

Topological domain

Cytoplasmic

Hgene

CLDN10

chr13:96229592

chr11:113220795

ENST00000376873

182_228

188

227.0

Topological domain

Cytoplasmic

Hgene

CLDN10

chr13:96212717

chr11:113220795

ENST00000299339

161_181

154

229.0

Transmembrane

Helical

Hgene

CLDN10

chr13:96212717

chr11:113220795

ENST00000376873

161_181

152

227.0

Transmembrane

Helical

Tgene

TTC12

chr13:96212717

chr11:113220795

ENST00000314756

106_139

384

733.0

Repeat

Note=TPR 1

Tgene

TTC12

chr13:96212717

chr11:113220795

ENST00000314756

140_173

384

733.0

Repeat

Note=TPR 2

Tgene

TTC12

chr13:96212717

chr11:113220795

ENST00000314756

174_207

384

733.0

Repeat

Note=TPR 3

Tgene

TTC12

chr13:96212717

chr11:113220795

ENST00000529221

106_139

384

706.0

Repeat

Note=TPR 1

Tgene

TTC12

chr13:96212717

chr11:113220795

ENST00000529221

140_173

384

706.0

Repeat

Note=TPR 2

Tgene

TTC12

chr13:96212717

chr11:113220795

ENST00000529221

174_207

384

706.0

Repeat

Note=TPR 3

Tgene

TTC12

chr13:96229592

chr11:113220795

ENST00000314756

106_139

384

733.0

Repeat

Note=TPR 1

Tgene

TTC12

chr13:96229592

chr11:113220795

ENST00000314756

140_173

384

733.0

Repeat

Note=TPR 2

Tgene

TTC12

chr13:96229592

chr11:113220795

ENST00000314756

174_207

384

733.0

Repeat

Note=TPR 3

Tgene

TTC12

chr13:96229592

chr11:113220795

ENST00000529221

106_139

384

706.0

Repeat

Note=TPR 1

Tgene

TTC12

chr13:96229592

chr11:113220795

ENST00000529221

140_173

384

706.0

Repeat

Note=TPR 2

Tgene

TTC12

chr13:96229592

chr11:113220795

ENST00000529221

174_207

384

706.0

Repeat

Note=TPR 3

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Fusion Gene Sequence for CLDN10-TTC12

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>17019_17019_1_CLDN10-TTC12_CLDN10_chr13_96212717_ENST00000299339_TTC12_chr11_113220795_ENST00000314756_length(transcript)=1538nt_BP=493nt
GGAGAGCGAGCGCGGCTGCAGCCGGCGGCATGGCTAGCACGGCTTCGGAGATCATCGCCTTCATGGTCTCCATCTCAGGCTGGGTACTGG
TGTCCTCCACGCTGCCCACCGACTACTGGAAGGTGTCTACCATCGACGGCACGGTCATCACAACCGCCACCTATTGGGCCAACCTGTGGA
AGGCGTGCGTTACCGACTCCACGGGCGTCTCCAACTGCAAGGACTTCCCCTCCATGCTGGCGCTGGACGGTTATATACAGGCATGTAGAG
GACTTATGATCGCTGCTGTCAGCCTGGGCTTCTTTGGTTCCATATTTGCGCTCTTTGGAATGAAGTGTACCAAAGTCGGAGGCTCCGATA
AAGCCAAAGCTAAAATTGCTTGTTTGGCTGGGATTGTATTCATACTGTCAGGGCTGTGCTCAATGACTGGATGTTCCCTATATGCAAACA
AAATCACAACGGAATTCTTTGATCCTCTCTTTGTTGAGCAAAAATTATTGGAAGCGCTGGTGTCATTTCTTGATTTCTCGGATAAGGAGG
CCAACACTGCTATGGGACTGTTCACAGACTTGGCTCTGGAAGAAAGATTCCAAGTCTGGTTCCAGGCCAACCTTCCAGGTGTTCTCCCTG
CACTCACAGGCGTTCTGAAGACAGATCCCAAGGTAAGCAGCTCCTCGGCTCTGTGCCAGTGCATTGCCATCATGGGAAACCTCAGTGCTG
AGCCCACTACCCGAAGACACATGGCGGCCTGTGAGGAATTTGGGGATGGCTGCTTGAGCCTCCTGGCCAGGTGTGAGGAGGATGTGGACC
TGTTCAGAGAGGTTATCTACACACTCCTGGGACTCATGATGAACCTGTGTCTTCAGGCTCCCTTTGTCTCTGAGGTTTGGGCTGTGGAGG
TGAGCAGAAGGTGCCTGTCTTTACTAAACAGCCAGGATGGAGGAATCCTGACAAGAGCTGCTGGTGTTCTGAGCCGGACCCTTTCTTCCT
CTCTGAAAATTGTTGAGGAGGCCTTGCGAGCAGGAGTGGTAAAGAAAATGATGAAATTCCTGAAGACAGGAGGTGAGACTGCATCACGTT
ATGCTATAAAGATACTAGCTATCTGCACGAATAGTTATCATGAAGCTCGGGAAGAAGTAATAAGACTGGATAAAAAGTTGAGCGTTATGA
TGAAGCTGCTCAGCTCGGAGGATGAGGTTCTGGTGGGCAACGCTGCCCTCTGCCTTGGTAACTGCATGGAGGTGCCCAACGTTGCGTCTT
CCCTGCTAAAGACGGACCTTTTGCAGGTCTTGTTAAAGCTTGCAGGCAGTGACACACAGAAGACGGCCGTGCAGGTGAACGCAGGCATTG
CTCTGGGGAAGCTGTGCACAGCTGAGCCCAGAGTGCCTGCCGAGAGCAGTCATCTCCAATTTGGAAGAGAGTCTGCTGCACCTGAAGCTC
TGTCTCCTCGCAGGTGGGAAGAGATGTTTCACATGCTAGTATTCTCCCTCTCCAGTGTGGATCCACCCCCGCCACCGCCCCAAACTTGTT

>17019_17019_1_CLDN10-TTC12_CLDN10_chr13_96212717_ENST00000299339_TTC12_chr11_113220795_ENST00000314756_length(amino acids)=503AA_BP=155
MASTASEIIAFMVSISGWVLVSSTLPTDYWKVSTIDGTVITTATYWANLWKACVTDSTGVSNCKDFPSMLALDGYIQACRGLMIAAVSLG
FFGSIFALFGMKCTKVGGSDKAKAKIACLAGIVFILSGLCSMTGCSLYANKITTEFFDPLFVEQKLLEALVSFLDFSDKEANTAMGLFTD
LALEERFQVWFQANLPGVLPALTGVLKTDPKVSSSSALCQCIAIMGNLSAEPTTRRHMAACEEFGDGCLSLLARCEEDVDLFREVIYTLL
GLMMNLCLQAPFVSEVWAVEVSRRCLSLLNSQDGGILTRAAGVLSRTLSSSLKIVEEALRAGVVKKMMKFLKTGGETASRYAIKILAICT
NSYHEAREEVIRLDKKLSVMMKLLSSEDEVLVGNAALCLGNCMEVPNVASSLLKTDLLQVLLKLAGSDTQKTAVQVNAGIALGKLCTAEP

--------------------------------------------------------------
>17019_17019_2_CLDN10-TTC12_CLDN10_chr13_96212717_ENST00000299339_TTC12_chr11_113220795_ENST00000393020_length(transcript)=1475nt_BP=493nt
GGAGAGCGAGCGCGGCTGCAGCCGGCGGCATGGCTAGCACGGCTTCGGAGATCATCGCCTTCATGGTCTCCATCTCAGGCTGGGTACTGG
TGTCCTCCACGCTGCCCACCGACTACTGGAAGGTGTCTACCATCGACGGCACGGTCATCACAACCGCCACCTATTGGGCCAACCTGTGGA
AGGCGTGCGTTACCGACTCCACGGGCGTCTCCAACTGCAAGGACTTCCCCTCCATGCTGGCGCTGGACGGTTATATACAGGCATGTAGAG
GACTTATGATCGCTGCTGTCAGCCTGGGCTTCTTTGGTTCCATATTTGCGCTCTTTGGAATGAAGTGTACCAAAGTCGGAGGCTCCGATA
AAGCCAAAGCTAAAATTGCTTGTTTGGCTGGGATTGTATTCATACTGTCAGGGCTGTGCTCAATGACTGGATGTTCCCTATATGCAAACA
AAATCACAACGGAATTCTTTGATCCTCTCTTTGTTGAGCAAAAATTATTGGAAGCGCTGGTGTCATTTCTTGATTTCTCGGATAAGGAGG
CCAACACTGCTATGGGACTGTTCACAGACTTGGCTCTGGAAGAAAGATTCCAAGTCTGGTTCCAGGCCAACCTTCCAGGTGTTCTCCCTG
CACTCACAGGCGTTCTGAAGACAGATCCCAAGGTAAGCAGCTCCTCGGCTCTGTGCCAGTGCATTGCCATCATGGGAAACCTCAGTGCTG
AGCCCACTACCCGAAGACACATGGCGGCCTGTGAGGAATTTGGGGATGGCTGCTTGAGCCTCCTGGCCAGGTGTGAGGAGGATGTGGACC
TGTTCAGAGAGGTTATCTACACACTCCTGGGACTCATGATGAACCTGTGTCTTCAGGCTCCCTTTGTCTCTGAGGTTTGGGCTGTGGAGG
TGAGCAGAAGGTGCCTGTCTTTACTAAACAGCCAGGATGGAGGAATCCTGACAAGAGCTGCTGGTGTTCTGAGCCGGACCCTTTCTTCCT
CTCTGAAAATTGTTGAGGAGGCCTTGCGAGCAGGAGTGGTAAAGAAAATGATGAAATTCCTGAAGACAGGAGGTGAGACTGCATCACGTT
ATGCTATAAAGATACTAGCTATCTGCACGAATAGTTATCATGAAGCTCGGGAAGAAGTAATAAGACTGGATAAAAGAGCCCCGACACCAC
CCTTGGAGACACGGCTTGTTCCAGGTAATCAGAGTCTTCTGGTTCAACAAGCAGAGGAGCTGGGATTTTCCATCCTAAAGAGGATGTGGC
CGGGATGGAACTCCATCACCATCCTGAAGCCACAGCAGAGGTGGCAGAATTCTCTGGGGCCTCATCCAAGTGGCTGTGTATATCAGTAGT
TGCTGAGTCCTATTCCATAATACAGCACTATGGTGTGTTTAGCCATTCATTGGTTGAAGGACATCTGAGCGGTTTCCAGATTTTAGCTAT

>17019_17019_2_CLDN10-TTC12_CLDN10_chr13_96212717_ENST00000299339_TTC12_chr11_113220795_ENST00000393020_length(amino acids)=439AA_BP=155
MASTASEIIAFMVSISGWVLVSSTLPTDYWKVSTIDGTVITTATYWANLWKACVTDSTGVSNCKDFPSMLALDGYIQACRGLMIAAVSLG
FFGSIFALFGMKCTKVGGSDKAKAKIACLAGIVFILSGLCSMTGCSLYANKITTEFFDPLFVEQKLLEALVSFLDFSDKEANTAMGLFTD
LALEERFQVWFQANLPGVLPALTGVLKTDPKVSSSSALCQCIAIMGNLSAEPTTRRHMAACEEFGDGCLSLLARCEEDVDLFREVIYTLL
GLMMNLCLQAPFVSEVWAVEVSRRCLSLLNSQDGGILTRAAGVLSRTLSSSLKIVEEALRAGVVKKMMKFLKTGGETASRYAIKILAICT

--------------------------------------------------------------
>17019_17019_3_CLDN10-TTC12_CLDN10_chr13_96212717_ENST00000299339_TTC12_chr11_113220795_ENST00000483239_length(transcript)=1544nt_BP=493nt
GGAGAGCGAGCGCGGCTGCAGCCGGCGGCATGGCTAGCACGGCTTCGGAGATCATCGCCTTCATGGTCTCCATCTCAGGCTGGGTACTGG
TGTCCTCCACGCTGCCCACCGACTACTGGAAGGTGTCTACCATCGACGGCACGGTCATCACAACCGCCACCTATTGGGCCAACCTGTGGA
AGGCGTGCGTTACCGACTCCACGGGCGTCTCCAACTGCAAGGACTTCCCCTCCATGCTGGCGCTGGACGGTTATATACAGGCATGTAGAG
GACTTATGATCGCTGCTGTCAGCCTGGGCTTCTTTGGTTCCATATTTGCGCTCTTTGGAATGAAGTGTACCAAAGTCGGAGGCTCCGATA
AAGCCAAAGCTAAAATTGCTTGTTTGGCTGGGATTGTATTCATACTGTCAGGGCTGTGCTCAATGACTGGATGTTCCCTATATGCAAACA
AAATCACAACGGAATTCTTTGATCCTCTCTTTGTTGAGCAAAAATTATTGGAAGCGCTGGTGTCATTTCTTGATTTCTCGGATAAGGAGG
CCAACACTGCTATGGGACTGTTCACAGACTTGGCTCTGGAAGAAAGATTCCAAGTCTGGTTCCAGGCCAACCTTCCAGGTGTTCTCCCTG
CACTCACAGGCGTTCTGAAGACAGATCCCAAGGTAAGCAGCTCCTCGGCTCTGTGCCAGTGCATTGCCATCATGGGAAACCTCAGTGCTG
AGCCCACTACCCGAAGACACATGGCGGCCTGTGAGGAATTTGGGGATGGCTGCTTGAGCCTCCTGGCCAGGTGTGAGGAGGATGTGGACC
TGTTCAGAGAGGTTATCTACACACTCCTGGGACTCATGATGAACCTGTGTCTTCAGGCTCCCTTTGTCTCTGAGGTTTGGGCTGTGGAGG
TGAGCAGAAGGTGCCTGTCTTTACTAAACAGCCAGGATGGAGGAATCCTGACAAGAGCTGCTGGTGTTCTGAGCCGGACCCTTTCTTCCT
CTCTGAAAATTGTTGAGGAGGCCTTGCGAGCAGGAGTGGTAAAGAAAATGATGAAATTCCTGAAGACAGGAGGTGAGACTGCATCACGTT
ATGCTATAAAGATACTAGCTATCTGCACGAATAGTTATCATGAAGCTCGGGAAGAAGTAATAAGACTGGATAAAAAGTTGAGCGTTATGA
TGAAGCTGCTCAGCTCGGAGGATGAGGTTCTGGTGGGCAACGCTGCCCTCTGCCTTGGTAACTGCATGGAGGTGCCCAACGTTGCGTCTT
CCCTGCTAAAGACGGACCTTTTGCAGGTCTTGTTAAAGCTTGCAGGCAGTGACACACAGAAGACGGCCGTGCAGGTGAACGCAGGCATTG
CTCTGGGGAAGCTGTGCACAGCTGAGCCCAGATTTGCTGCTCAACTGAGAAAGCTTCATGGCCTAGAAATTCTCAACTCTACGATGAAAT
ACATCAGTGATTCTTGAGAGAGACAGGGTTTGTGTGCATTTGGGGAACACACAGATGCACACCGTGTGTTGTTCCTATGCTAATAAAGAC

>17019_17019_3_CLDN10-TTC12_CLDN10_chr13_96212717_ENST00000299339_TTC12_chr11_113220795_ENST00000483239_length(amino acids)=475AA_BP=155
MASTASEIIAFMVSISGWVLVSSTLPTDYWKVSTIDGTVITTATYWANLWKACVTDSTGVSNCKDFPSMLALDGYIQACRGLMIAAVSLG
FFGSIFALFGMKCTKVGGSDKAKAKIACLAGIVFILSGLCSMTGCSLYANKITTEFFDPLFVEQKLLEALVSFLDFSDKEANTAMGLFTD
LALEERFQVWFQANLPGVLPALTGVLKTDPKVSSSSALCQCIAIMGNLSAEPTTRRHMAACEEFGDGCLSLLARCEEDVDLFREVIYTLL
GLMMNLCLQAPFVSEVWAVEVSRRCLSLLNSQDGGILTRAAGVLSRTLSSSLKIVEEALRAGVVKKMMKFLKTGGETASRYAIKILAICT
NSYHEAREEVIRLDKKLSVMMKLLSSEDEVLVGNAALCLGNCMEVPNVASSLLKTDLLQVLLKLAGSDTQKTAVQVNAGIALGKLCTAEP

--------------------------------------------------------------
>17019_17019_4_CLDN10-TTC12_CLDN10_chr13_96212717_ENST00000299339_TTC12_chr11_113220795_ENST00000529221_length(transcript)=1549nt_BP=493nt
GGAGAGCGAGCGCGGCTGCAGCCGGCGGCATGGCTAGCACGGCTTCGGAGATCATCGCCTTCATGGTCTCCATCTCAGGCTGGGTACTGG
TGTCCTCCACGCTGCCCACCGACTACTGGAAGGTGTCTACCATCGACGGCACGGTCATCACAACCGCCACCTATTGGGCCAACCTGTGGA
AGGCGTGCGTTACCGACTCCACGGGCGTCTCCAACTGCAAGGACTTCCCCTCCATGCTGGCGCTGGACGGTTATATACAGGCATGTAGAG
GACTTATGATCGCTGCTGTCAGCCTGGGCTTCTTTGGTTCCATATTTGCGCTCTTTGGAATGAAGTGTACCAAAGTCGGAGGCTCCGATA
AAGCCAAAGCTAAAATTGCTTGTTTGGCTGGGATTGTATTCATACTGTCAGGGCTGTGCTCAATGACTGGATGTTCCCTATATGCAAACA
AAATCACAACGGAATTCTTTGATCCTCTCTTTGTTGAGCAAAAATTATTGGAAGCGCTGGTGTCATTTCTTGATTTCTCGGATAAGGAGG
CCAACACTGCTATGGGACTGTTCACAGACTTGGCTCTGGAAGAAAGATTCCAAGTCTGGTTCCAGGCCAACCTTCCAGGTGTTCTCCCTG
CACTCACAGGCGTTCTGAAGACAGATCCCAAGGTAAGCAGCTCCTCGGCTCTGTGCCAGTGCATTGCCATCATGGGAAACCTCAGTGCTG
AGCCCACTACCCGAAGACACATGGCGGCCTGTGAGGAATTTGGGGATGGCTGCTTGAGCCTCCTGGCCAGGTGTGAGGAGGATGTGGACC
TGTTCAGAGAGGTTATCTACACACTCCTGGGACTCATGATGAACCTGTGTCTTCAGGCTCCCTTTGTCTCTGAGGTTTGGGCTGTGGAGG
TGAGCAGAAGGTGCCTGTCTTTACTAAACAGCCAGGATGGAGGAATCCTGACAAGAGCTGCTGGTGTTCTGAGCCGGACCCTTTCTTCCT
CTCTGAAAATTGTTGAGGAGGCCTTGCGAGCAGGAGTGGTAAAGAAAATGATGAAATTCCTGAAGACAGGAGGTGAGACTGCATCACGTT
ATGCTATAAAGATACTAGCTATCTGCACGAATAGTTATCATGAAGCTCGGGAAGAAGTAATAAGACTGGATAAAAAGTTGAGCGTTATGA
TGAAGCTGCTCAGCTCGGAGGATGAGGTTCTGGTGGGCAACGCTGCCCTCTGCCTTGGTAACTGCATGGAGGTGCCCAACGTTGCGTCTT
CCCTGCTAAAGACGGACCTTTTGCAGGTCTTGTTAAAGCTTGCAGGCAGTGACACACAGAAGACGGCCGTGCAGGTGAACGCAGGCATTG
CTCTGGGGAAGCTGTGCACAGCTGAGCCCAGATTTGCTGCTCAACTGAGAAAGCTTCATGGCCTAGAAATTCTCAACTCTACGATGAAAT
ACATCAGTGATTCTTGAGAGAGACAGGGTTTGTGTGCATTTGGGGAACACACAGATGCACACCGTGTGTTGTTCCTATGCTAATAAAGAC

>17019_17019_4_CLDN10-TTC12_CLDN10_chr13_96212717_ENST00000299339_TTC12_chr11_113220795_ENST00000529221_length(amino acids)=475AA_BP=155
MASTASEIIAFMVSISGWVLVSSTLPTDYWKVSTIDGTVITTATYWANLWKACVTDSTGVSNCKDFPSMLALDGYIQACRGLMIAAVSLG
FFGSIFALFGMKCTKVGGSDKAKAKIACLAGIVFILSGLCSMTGCSLYANKITTEFFDPLFVEQKLLEALVSFLDFSDKEANTAMGLFTD
LALEERFQVWFQANLPGVLPALTGVLKTDPKVSSSSALCQCIAIMGNLSAEPTTRRHMAACEEFGDGCLSLLARCEEDVDLFREVIYTLL
GLMMNLCLQAPFVSEVWAVEVSRRCLSLLNSQDGGILTRAAGVLSRTLSSSLKIVEEALRAGVVKKMMKFLKTGGETASRYAIKILAICT
NSYHEAREEVIRLDKKLSVMMKLLSSEDEVLVGNAALCLGNCMEVPNVASSLLKTDLLQVLLKLAGSDTQKTAVQVNAGIALGKLCTAEP

--------------------------------------------------------------
>17019_17019_5_CLDN10-TTC12_CLDN10_chr13_96212717_ENST00000376873_TTC12_chr11_113220795_ENST00000314756_length(transcript)=1733nt_BP=688nt
ATATCCGTGTAGAAAATCAGAACGACTCTTTCAGGCCATCTTTAAAATGTCATTGGTAAACCATACTTGATCCTAAATTCCTGTACTTCC
TCAGGCCATCCGAGCATGAAACGCTGTCACCTACCCACATCCGCTGGCTGTGACGCTTGTCAAAGTGTTCTCTATCGGCTGCATGCCTAG
ACCACCAAAGCGTTCTGACCGGACAGTGTCACTGGAGAAGGCGGCGCGACATGTCCAGGGCGCAGATCTGGGCTCTGGTGTCTGGTGTCG
GAGGGTTTGGAGCTCTCGTTGCTGCTACCACGTCCAATGAGTGGAAAGTGACCACGCGAGCCTCCTCGGTGATAACAGCCACTTGGGTTT
ACCAGGGTCTGTGGATGAACTGCGCAGGTAACGCGTTGGGTTCTTTCCATTGCCGACCGCATTTTACTATCTTCAAAGTAGCAGGTTATA
TACAGGCATGTAGAGGACTTATGATCGCTGCTGTCAGCCTGGGCTTCTTTGGTTCCATATTTGCGCTCTTTGGAATGAAGTGTACCAAAG
TCGGAGGCTCCGATAAAGCCAAAGCTAAAATTGCTTGTTTGGCTGGGATTGTATTCATACTGTCAGGGCTGTGCTCAATGACTGGATGTT
CCCTATATGCAAACAAAATCACAACGGAATTCTTTGATCCTCTCTTTGTTGAGCAAAAATTATTGGAAGCGCTGGTGTCATTTCTTGATT
TCTCGGATAAGGAGGCCAACACTGCTATGGGACTGTTCACAGACTTGGCTCTGGAAGAAAGATTCCAAGTCTGGTTCCAGGCCAACCTTC
CAGGTGTTCTCCCTGCACTCACAGGCGTTCTGAAGACAGATCCCAAGGTAAGCAGCTCCTCGGCTCTGTGCCAGTGCATTGCCATCATGG
GAAACCTCAGTGCTGAGCCCACTACCCGAAGACACATGGCGGCCTGTGAGGAATTTGGGGATGGCTGCTTGAGCCTCCTGGCCAGGTGTG
AGGAGGATGTGGACCTGTTCAGAGAGGTTATCTACACACTCCTGGGACTCATGATGAACCTGTGTCTTCAGGCTCCCTTTGTCTCTGAGG
TTTGGGCTGTGGAGGTGAGCAGAAGGTGCCTGTCTTTACTAAACAGCCAGGATGGAGGAATCCTGACAAGAGCTGCTGGTGTTCTGAGCC
GGACCCTTTCTTCCTCTCTGAAAATTGTTGAGGAGGCCTTGCGAGCAGGAGTGGTAAAGAAAATGATGAAATTCCTGAAGACAGGAGGTG
AGACTGCATCACGTTATGCTATAAAGATACTAGCTATCTGCACGAATAGTTATCATGAAGCTCGGGAAGAAGTAATAAGACTGGATAAAA
AGTTGAGCGTTATGATGAAGCTGCTCAGCTCGGAGGATGAGGTTCTGGTGGGCAACGCTGCCCTCTGCCTTGGTAACTGCATGGAGGTGC
CCAACGTTGCGTCTTCCCTGCTAAAGACGGACCTTTTGCAGGTCTTGTTAAAGCTTGCAGGCAGTGACACACAGAAGACGGCCGTGCAGG
TGAACGCAGGCATTGCTCTGGGGAAGCTGTGCACAGCTGAGCCCAGAGTGCCTGCCGAGAGCAGTCATCTCCAATTTGGAAGAGAGTCTG
CTGCACCTGAAGCTCTGTCTCCTCGCAGGTGGGAAGAGATGTTTCACATGCTAGTATTCTCCCTCTCCAGTGTGGATCCACCCCCGCCAC

>17019_17019_5_CLDN10-TTC12_CLDN10_chr13_96212717_ENST00000376873_TTC12_chr11_113220795_ENST00000314756_length(amino acids)=529AA_BP=181
MSKCSLSAACLDHQSVLTGQCHWRRRRDMSRAQIWALVSGVGGFGALVAATTSNEWKVTTRASSVITATWVYQGLWMNCAGNALGSFHCR
PHFTIFKVAGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDKAKAKIACLAGIVFILSGLCSMTGCSLYANKITTEFFDPLFVEQ
KLLEALVSFLDFSDKEANTAMGLFTDLALEERFQVWFQANLPGVLPALTGVLKTDPKVSSSSALCQCIAIMGNLSAEPTTRRHMAACEEF
GDGCLSLLARCEEDVDLFREVIYTLLGLMMNLCLQAPFVSEVWAVEVSRRCLSLLNSQDGGILTRAAGVLSRTLSSSLKIVEEALRAGVV
KKMMKFLKTGGETASRYAIKILAICTNSYHEAREEVIRLDKKLSVMMKLLSSEDEVLVGNAALCLGNCMEVPNVASSLLKTDLLQVLLKL

--------------------------------------------------------------
>17019_17019_6_CLDN10-TTC12_CLDN10_chr13_96212717_ENST00000376873_TTC12_chr11_113220795_ENST00000393020_length(transcript)=1670nt_BP=688nt
ATATCCGTGTAGAAAATCAGAACGACTCTTTCAGGCCATCTTTAAAATGTCATTGGTAAACCATACTTGATCCTAAATTCCTGTACTTCC
TCAGGCCATCCGAGCATGAAACGCTGTCACCTACCCACATCCGCTGGCTGTGACGCTTGTCAAAGTGTTCTCTATCGGCTGCATGCCTAG
ACCACCAAAGCGTTCTGACCGGACAGTGTCACTGGAGAAGGCGGCGCGACATGTCCAGGGCGCAGATCTGGGCTCTGGTGTCTGGTGTCG
GAGGGTTTGGAGCTCTCGTTGCTGCTACCACGTCCAATGAGTGGAAAGTGACCACGCGAGCCTCCTCGGTGATAACAGCCACTTGGGTTT
ACCAGGGTCTGTGGATGAACTGCGCAGGTAACGCGTTGGGTTCTTTCCATTGCCGACCGCATTTTACTATCTTCAAAGTAGCAGGTTATA
TACAGGCATGTAGAGGACTTATGATCGCTGCTGTCAGCCTGGGCTTCTTTGGTTCCATATTTGCGCTCTTTGGAATGAAGTGTACCAAAG
TCGGAGGCTCCGATAAAGCCAAAGCTAAAATTGCTTGTTTGGCTGGGATTGTATTCATACTGTCAGGGCTGTGCTCAATGACTGGATGTT
CCCTATATGCAAACAAAATCACAACGGAATTCTTTGATCCTCTCTTTGTTGAGCAAAAATTATTGGAAGCGCTGGTGTCATTTCTTGATT
TCTCGGATAAGGAGGCCAACACTGCTATGGGACTGTTCACAGACTTGGCTCTGGAAGAAAGATTCCAAGTCTGGTTCCAGGCCAACCTTC
CAGGTGTTCTCCCTGCACTCACAGGCGTTCTGAAGACAGATCCCAAGGTAAGCAGCTCCTCGGCTCTGTGCCAGTGCATTGCCATCATGG
GAAACCTCAGTGCTGAGCCCACTACCCGAAGACACATGGCGGCCTGTGAGGAATTTGGGGATGGCTGCTTGAGCCTCCTGGCCAGGTGTG
AGGAGGATGTGGACCTGTTCAGAGAGGTTATCTACACACTCCTGGGACTCATGATGAACCTGTGTCTTCAGGCTCCCTTTGTCTCTGAGG
TTTGGGCTGTGGAGGTGAGCAGAAGGTGCCTGTCTTTACTAAACAGCCAGGATGGAGGAATCCTGACAAGAGCTGCTGGTGTTCTGAGCC
GGACCCTTTCTTCCTCTCTGAAAATTGTTGAGGAGGCCTTGCGAGCAGGAGTGGTAAAGAAAATGATGAAATTCCTGAAGACAGGAGGTG
AGACTGCATCACGTTATGCTATAAAGATACTAGCTATCTGCACGAATAGTTATCATGAAGCTCGGGAAGAAGTAATAAGACTGGATAAAA
GAGCCCCGACACCACCCTTGGAGACACGGCTTGTTCCAGGTAATCAGAGTCTTCTGGTTCAACAAGCAGAGGAGCTGGGATTTTCCATCC
TAAAGAGGATGTGGCCGGGATGGAACTCCATCACCATCCTGAAGCCACAGCAGAGGTGGCAGAATTCTCTGGGGCCTCATCCAAGTGGCT
GTGTATATCAGTAGTTGCTGAGTCCTATTCCATAATACAGCACTATGGTGTGTTTAGCCATTCATTGGTTGAAGGACATCTGAGCGGTTT

>17019_17019_6_CLDN10-TTC12_CLDN10_chr13_96212717_ENST00000376873_TTC12_chr11_113220795_ENST00000393020_length(amino acids)=465AA_BP=181
MSKCSLSAACLDHQSVLTGQCHWRRRRDMSRAQIWALVSGVGGFGALVAATTSNEWKVTTRASSVITATWVYQGLWMNCAGNALGSFHCR
PHFTIFKVAGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDKAKAKIACLAGIVFILSGLCSMTGCSLYANKITTEFFDPLFVEQ
KLLEALVSFLDFSDKEANTAMGLFTDLALEERFQVWFQANLPGVLPALTGVLKTDPKVSSSSALCQCIAIMGNLSAEPTTRRHMAACEEF
GDGCLSLLARCEEDVDLFREVIYTLLGLMMNLCLQAPFVSEVWAVEVSRRCLSLLNSQDGGILTRAAGVLSRTLSSSLKIVEEALRAGVV
KKMMKFLKTGGETASRYAIKILAICTNSYHEAREEVIRLDKRAPTPPLETRLVPGNQSLLVQQAEELGFSILKRMWPGWNSITILKPQQR

--------------------------------------------------------------
>17019_17019_7_CLDN10-TTC12_CLDN10_chr13_96212717_ENST00000376873_TTC12_chr11_113220795_ENST00000483239_length(transcript)=1739nt_BP=688nt
ATATCCGTGTAGAAAATCAGAACGACTCTTTCAGGCCATCTTTAAAATGTCATTGGTAAACCATACTTGATCCTAAATTCCTGTACTTCC
TCAGGCCATCCGAGCATGAAACGCTGTCACCTACCCACATCCGCTGGCTGTGACGCTTGTCAAAGTGTTCTCTATCGGCTGCATGCCTAG
ACCACCAAAGCGTTCTGACCGGACAGTGTCACTGGAGAAGGCGGCGCGACATGTCCAGGGCGCAGATCTGGGCTCTGGTGTCTGGTGTCG
GAGGGTTTGGAGCTCTCGTTGCTGCTACCACGTCCAATGAGTGGAAAGTGACCACGCGAGCCTCCTCGGTGATAACAGCCACTTGGGTTT
ACCAGGGTCTGTGGATGAACTGCGCAGGTAACGCGTTGGGTTCTTTCCATTGCCGACCGCATTTTACTATCTTCAAAGTAGCAGGTTATA
TACAGGCATGTAGAGGACTTATGATCGCTGCTGTCAGCCTGGGCTTCTTTGGTTCCATATTTGCGCTCTTTGGAATGAAGTGTACCAAAG
TCGGAGGCTCCGATAAAGCCAAAGCTAAAATTGCTTGTTTGGCTGGGATTGTATTCATACTGTCAGGGCTGTGCTCAATGACTGGATGTT
CCCTATATGCAAACAAAATCACAACGGAATTCTTTGATCCTCTCTTTGTTGAGCAAAAATTATTGGAAGCGCTGGTGTCATTTCTTGATT
TCTCGGATAAGGAGGCCAACACTGCTATGGGACTGTTCACAGACTTGGCTCTGGAAGAAAGATTCCAAGTCTGGTTCCAGGCCAACCTTC
CAGGTGTTCTCCCTGCACTCACAGGCGTTCTGAAGACAGATCCCAAGGTAAGCAGCTCCTCGGCTCTGTGCCAGTGCATTGCCATCATGG
GAAACCTCAGTGCTGAGCCCACTACCCGAAGACACATGGCGGCCTGTGAGGAATTTGGGGATGGCTGCTTGAGCCTCCTGGCCAGGTGTG
AGGAGGATGTGGACCTGTTCAGAGAGGTTATCTACACACTCCTGGGACTCATGATGAACCTGTGTCTTCAGGCTCCCTTTGTCTCTGAGG
TTTGGGCTGTGGAGGTGAGCAGAAGGTGCCTGTCTTTACTAAACAGCCAGGATGGAGGAATCCTGACAAGAGCTGCTGGTGTTCTGAGCC
GGACCCTTTCTTCCTCTCTGAAAATTGTTGAGGAGGCCTTGCGAGCAGGAGTGGTAAAGAAAATGATGAAATTCCTGAAGACAGGAGGTG
AGACTGCATCACGTTATGCTATAAAGATACTAGCTATCTGCACGAATAGTTATCATGAAGCTCGGGAAGAAGTAATAAGACTGGATAAAA
AGTTGAGCGTTATGATGAAGCTGCTCAGCTCGGAGGATGAGGTTCTGGTGGGCAACGCTGCCCTCTGCCTTGGTAACTGCATGGAGGTGC
CCAACGTTGCGTCTTCCCTGCTAAAGACGGACCTTTTGCAGGTCTTGTTAAAGCTTGCAGGCAGTGACACACAGAAGACGGCCGTGCAGG
TGAACGCAGGCATTGCTCTGGGGAAGCTGTGCACAGCTGAGCCCAGATTTGCTGCTCAACTGAGAAAGCTTCATGGCCTAGAAATTCTCA
ACTCTACGATGAAATACATCAGTGATTCTTGAGAGAGACAGGGTTTGTGTGCATTTGGGGAACACACAGATGCACACCGTGTGTTGTTCC

>17019_17019_7_CLDN10-TTC12_CLDN10_chr13_96212717_ENST00000376873_TTC12_chr11_113220795_ENST00000483239_length(amino acids)=501AA_BP=181
MSKCSLSAACLDHQSVLTGQCHWRRRRDMSRAQIWALVSGVGGFGALVAATTSNEWKVTTRASSVITATWVYQGLWMNCAGNALGSFHCR
PHFTIFKVAGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDKAKAKIACLAGIVFILSGLCSMTGCSLYANKITTEFFDPLFVEQ
KLLEALVSFLDFSDKEANTAMGLFTDLALEERFQVWFQANLPGVLPALTGVLKTDPKVSSSSALCQCIAIMGNLSAEPTTRRHMAACEEF
GDGCLSLLARCEEDVDLFREVIYTLLGLMMNLCLQAPFVSEVWAVEVSRRCLSLLNSQDGGILTRAAGVLSRTLSSSLKIVEEALRAGVV
KKMMKFLKTGGETASRYAIKILAICTNSYHEAREEVIRLDKKLSVMMKLLSSEDEVLVGNAALCLGNCMEVPNVASSLLKTDLLQVLLKL

--------------------------------------------------------------
>17019_17019_8_CLDN10-TTC12_CLDN10_chr13_96212717_ENST00000376873_TTC12_chr11_113220795_ENST00000529221_length(transcript)=1744nt_BP=688nt
ATATCCGTGTAGAAAATCAGAACGACTCTTTCAGGCCATCTTTAAAATGTCATTGGTAAACCATACTTGATCCTAAATTCCTGTACTTCC
TCAGGCCATCCGAGCATGAAACGCTGTCACCTACCCACATCCGCTGGCTGTGACGCTTGTCAAAGTGTTCTCTATCGGCTGCATGCCTAG
ACCACCAAAGCGTTCTGACCGGACAGTGTCACTGGAGAAGGCGGCGCGACATGTCCAGGGCGCAGATCTGGGCTCTGGTGTCTGGTGTCG
GAGGGTTTGGAGCTCTCGTTGCTGCTACCACGTCCAATGAGTGGAAAGTGACCACGCGAGCCTCCTCGGTGATAACAGCCACTTGGGTTT
ACCAGGGTCTGTGGATGAACTGCGCAGGTAACGCGTTGGGTTCTTTCCATTGCCGACCGCATTTTACTATCTTCAAAGTAGCAGGTTATA
TACAGGCATGTAGAGGACTTATGATCGCTGCTGTCAGCCTGGGCTTCTTTGGTTCCATATTTGCGCTCTTTGGAATGAAGTGTACCAAAG
TCGGAGGCTCCGATAAAGCCAAAGCTAAAATTGCTTGTTTGGCTGGGATTGTATTCATACTGTCAGGGCTGTGCTCAATGACTGGATGTT
CCCTATATGCAAACAAAATCACAACGGAATTCTTTGATCCTCTCTTTGTTGAGCAAAAATTATTGGAAGCGCTGGTGTCATTTCTTGATT
TCTCGGATAAGGAGGCCAACACTGCTATGGGACTGTTCACAGACTTGGCTCTGGAAGAAAGATTCCAAGTCTGGTTCCAGGCCAACCTTC
CAGGTGTTCTCCCTGCACTCACAGGCGTTCTGAAGACAGATCCCAAGGTAAGCAGCTCCTCGGCTCTGTGCCAGTGCATTGCCATCATGG
GAAACCTCAGTGCTGAGCCCACTACCCGAAGACACATGGCGGCCTGTGAGGAATTTGGGGATGGCTGCTTGAGCCTCCTGGCCAGGTGTG
AGGAGGATGTGGACCTGTTCAGAGAGGTTATCTACACACTCCTGGGACTCATGATGAACCTGTGTCTTCAGGCTCCCTTTGTCTCTGAGG
TTTGGGCTGTGGAGGTGAGCAGAAGGTGCCTGTCTTTACTAAACAGCCAGGATGGAGGAATCCTGACAAGAGCTGCTGGTGTTCTGAGCC
GGACCCTTTCTTCCTCTCTGAAAATTGTTGAGGAGGCCTTGCGAGCAGGAGTGGTAAAGAAAATGATGAAATTCCTGAAGACAGGAGGTG
AGACTGCATCACGTTATGCTATAAAGATACTAGCTATCTGCACGAATAGTTATCATGAAGCTCGGGAAGAAGTAATAAGACTGGATAAAA
AGTTGAGCGTTATGATGAAGCTGCTCAGCTCGGAGGATGAGGTTCTGGTGGGCAACGCTGCCCTCTGCCTTGGTAACTGCATGGAGGTGC
CCAACGTTGCGTCTTCCCTGCTAAAGACGGACCTTTTGCAGGTCTTGTTAAAGCTTGCAGGCAGTGACACACAGAAGACGGCCGTGCAGG
TGAACGCAGGCATTGCTCTGGGGAAGCTGTGCACAGCTGAGCCCAGATTTGCTGCTCAACTGAGAAAGCTTCATGGCCTAGAAATTCTCA
ACTCTACGATGAAATACATCAGTGATTCTTGAGAGAGACAGGGTTTGTGTGCATTTGGGGAACACACAGATGCACACCGTGTGTTGTTCC

>17019_17019_8_CLDN10-TTC12_CLDN10_chr13_96212717_ENST00000376873_TTC12_chr11_113220795_ENST00000529221_length(amino acids)=501AA_BP=181
MSKCSLSAACLDHQSVLTGQCHWRRRRDMSRAQIWALVSGVGGFGALVAATTSNEWKVTTRASSVITATWVYQGLWMNCAGNALGSFHCR
PHFTIFKVAGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDKAKAKIACLAGIVFILSGLCSMTGCSLYANKITTEFFDPLFVEQ
KLLEALVSFLDFSDKEANTAMGLFTDLALEERFQVWFQANLPGVLPALTGVLKTDPKVSSSSALCQCIAIMGNLSAEPTTRRHMAACEEF
GDGCLSLLARCEEDVDLFREVIYTLLGLMMNLCLQAPFVSEVWAVEVSRRCLSLLNSQDGGILTRAAGVLSRTLSSSLKIVEEALRAGVV
KKMMKFLKTGGETASRYAIKILAICTNSYHEAREEVIRLDKKLSVMMKLLSSEDEVLVGNAALCLGNCMEVPNVASSLLKTDLLQVLLKL

--------------------------------------------------------------
>17019_17019_9_CLDN10-TTC12_CLDN10_chr13_96229592_ENST00000299339_TTC12_chr11_113220795_ENST00000314756_length(transcript)=1646nt_BP=601nt
GGAGAGCGAGCGCGGCTGCAGCCGGCGGCATGGCTAGCACGGCTTCGGAGATCATCGCCTTCATGGTCTCCATCTCAGGCTGGGTACTGG
TGTCCTCCACGCTGCCCACCGACTACTGGAAGGTGTCTACCATCGACGGCACGGTCATCACAACCGCCACCTATTGGGCCAACCTGTGGA
AGGCGTGCGTTACCGACTCCACGGGCGTCTCCAACTGCAAGGACTTCCCCTCCATGCTGGCGCTGGACGGTTATATACAGGCATGTAGAG
GACTTATGATCGCTGCTGTCAGCCTGGGCTTCTTTGGTTCCATATTTGCGCTCTTTGGAATGAAGTGTACCAAAGTCGGAGGCTCCGATA
AAGCCAAAGCTAAAATTGCTTGTTTGGCTGGGATTGTATTCATACTGTCAGGGCTGTGCTCAATGACTGGATGTTCCCTATATGCAAACA
AAATCACAACGGAATTCTTTGATCCTCTCTTTGTTGAGCAAAAGTATGAATTAGGAGCCGCTCTGTTTATTGGATGGGCAGGAGCCTCAC
TGTGCATAATTGGTGGTGTCATATTTTGCTTTTCAATATCTGACAACAACAAAACACCCAGATTATTGGAAGCGCTGGTGTCATTTCTTG
ATTTCTCGGATAAGGAGGCCAACACTGCTATGGGACTGTTCACAGACTTGGCTCTGGAAGAAAGATTCCAAGTCTGGTTCCAGGCCAACC
TTCCAGGTGTTCTCCCTGCACTCACAGGCGTTCTGAAGACAGATCCCAAGGTAAGCAGCTCCTCGGCTCTGTGCCAGTGCATTGCCATCA
TGGGAAACCTCAGTGCTGAGCCCACTACCCGAAGACACATGGCGGCCTGTGAGGAATTTGGGGATGGCTGCTTGAGCCTCCTGGCCAGGT
GTGAGGAGGATGTGGACCTGTTCAGAGAGGTTATCTACACACTCCTGGGACTCATGATGAACCTGTGTCTTCAGGCTCCCTTTGTCTCTG
AGGTTTGGGCTGTGGAGGTGAGCAGAAGGTGCCTGTCTTTACTAAACAGCCAGGATGGAGGAATCCTGACAAGAGCTGCTGGTGTTCTGA
GCCGGACCCTTTCTTCCTCTCTGAAAATTGTTGAGGAGGCCTTGCGAGCAGGAGTGGTAAAGAAAATGATGAAATTCCTGAAGACAGGAG
GTGAGACTGCATCACGTTATGCTATAAAGATACTAGCTATCTGCACGAATAGTTATCATGAAGCTCGGGAAGAAGTAATAAGACTGGATA
AAAAGTTGAGCGTTATGATGAAGCTGCTCAGCTCGGAGGATGAGGTTCTGGTGGGCAACGCTGCCCTCTGCCTTGGTAACTGCATGGAGG
TGCCCAACGTTGCGTCTTCCCTGCTAAAGACGGACCTTTTGCAGGTCTTGTTAAAGCTTGCAGGCAGTGACACACAGAAGACGGCCGTGC
AGGTGAACGCAGGCATTGCTCTGGGGAAGCTGTGCACAGCTGAGCCCAGAGTGCCTGCCGAGAGCAGTCATCTCCAATTTGGAAGAGAGT
CTGCTGCACCTGAAGCTCTGTCTCCTCGCAGGTGGGAAGAGATGTTTCACATGCTAGTATTCTCCCTCTCCAGTGTGGATCCACCCCCGC

>17019_17019_9_CLDN10-TTC12_CLDN10_chr13_96229592_ENST00000299339_TTC12_chr11_113220795_ENST00000314756_length(amino acids)=539AA_BP=185
MASTASEIIAFMVSISGWVLVSSTLPTDYWKVSTIDGTVITTATYWANLWKACVTDSTGVSNCKDFPSMLALDGYIQACRGLMIAAVSLG
FFGSIFALFGMKCTKVGGSDKAKAKIACLAGIVFILSGLCSMTGCSLYANKITTEFFDPLFVEQKYELGAALFIGWAGASLCIIGGVIFC
FSISDNNKTPRLLEALVSFLDFSDKEANTAMGLFTDLALEERFQVWFQANLPGVLPALTGVLKTDPKVSSSSALCQCIAIMGNLSAEPTT
RRHMAACEEFGDGCLSLLARCEEDVDLFREVIYTLLGLMMNLCLQAPFVSEVWAVEVSRRCLSLLNSQDGGILTRAAGVLSRTLSSSLKI
VEEALRAGVVKKMMKFLKTGGETASRYAIKILAICTNSYHEAREEVIRLDKKLSVMMKLLSSEDEVLVGNAALCLGNCMEVPNVASSLLK

--------------------------------------------------------------
>17019_17019_10_CLDN10-TTC12_CLDN10_chr13_96229592_ENST00000299339_TTC12_chr11_113220795_ENST00000393020_length(transcript)=1583nt_BP=601nt
GGAGAGCGAGCGCGGCTGCAGCCGGCGGCATGGCTAGCACGGCTTCGGAGATCATCGCCTTCATGGTCTCCATCTCAGGCTGGGTACTGG
TGTCCTCCACGCTGCCCACCGACTACTGGAAGGTGTCTACCATCGACGGCACGGTCATCACAACCGCCACCTATTGGGCCAACCTGTGGA
AGGCGTGCGTTACCGACTCCACGGGCGTCTCCAACTGCAAGGACTTCCCCTCCATGCTGGCGCTGGACGGTTATATACAGGCATGTAGAG
GACTTATGATCGCTGCTGTCAGCCTGGGCTTCTTTGGTTCCATATTTGCGCTCTTTGGAATGAAGTGTACCAAAGTCGGAGGCTCCGATA
AAGCCAAAGCTAAAATTGCTTGTTTGGCTGGGATTGTATTCATACTGTCAGGGCTGTGCTCAATGACTGGATGTTCCCTATATGCAAACA
AAATCACAACGGAATTCTTTGATCCTCTCTTTGTTGAGCAAAAGTATGAATTAGGAGCCGCTCTGTTTATTGGATGGGCAGGAGCCTCAC
TGTGCATAATTGGTGGTGTCATATTTTGCTTTTCAATATCTGACAACAACAAAACACCCAGATTATTGGAAGCGCTGGTGTCATTTCTTG
ATTTCTCGGATAAGGAGGCCAACACTGCTATGGGACTGTTCACAGACTTGGCTCTGGAAGAAAGATTCCAAGTCTGGTTCCAGGCCAACC
TTCCAGGTGTTCTCCCTGCACTCACAGGCGTTCTGAAGACAGATCCCAAGGTAAGCAGCTCCTCGGCTCTGTGCCAGTGCATTGCCATCA
TGGGAAACCTCAGTGCTGAGCCCACTACCCGAAGACACATGGCGGCCTGTGAGGAATTTGGGGATGGCTGCTTGAGCCTCCTGGCCAGGT
GTGAGGAGGATGTGGACCTGTTCAGAGAGGTTATCTACACACTCCTGGGACTCATGATGAACCTGTGTCTTCAGGCTCCCTTTGTCTCTG
AGGTTTGGGCTGTGGAGGTGAGCAGAAGGTGCCTGTCTTTACTAAACAGCCAGGATGGAGGAATCCTGACAAGAGCTGCTGGTGTTCTGA
GCCGGACCCTTTCTTCCTCTCTGAAAATTGTTGAGGAGGCCTTGCGAGCAGGAGTGGTAAAGAAAATGATGAAATTCCTGAAGACAGGAG
GTGAGACTGCATCACGTTATGCTATAAAGATACTAGCTATCTGCACGAATAGTTATCATGAAGCTCGGGAAGAAGTAATAAGACTGGATA
AAAGAGCCCCGACACCACCCTTGGAGACACGGCTTGTTCCAGGTAATCAGAGTCTTCTGGTTCAACAAGCAGAGGAGCTGGGATTTTCCA
TCCTAAAGAGGATGTGGCCGGGATGGAACTCCATCACCATCCTGAAGCCACAGCAGAGGTGGCAGAATTCTCTGGGGCCTCATCCAAGTG
GCTGTGTATATCAGTAGTTGCTGAGTCCTATTCCATAATACAGCACTATGGTGTGTTTAGCCATTCATTGGTTGAAGGACATCTGAGCGG

>17019_17019_10_CLDN10-TTC12_CLDN10_chr13_96229592_ENST00000299339_TTC12_chr11_113220795_ENST00000393020_length(amino acids)=475AA_BP=185
MASTASEIIAFMVSISGWVLVSSTLPTDYWKVSTIDGTVITTATYWANLWKACVTDSTGVSNCKDFPSMLALDGYIQACRGLMIAAVSLG
FFGSIFALFGMKCTKVGGSDKAKAKIACLAGIVFILSGLCSMTGCSLYANKITTEFFDPLFVEQKYELGAALFIGWAGASLCIIGGVIFC
FSISDNNKTPRLLEALVSFLDFSDKEANTAMGLFTDLALEERFQVWFQANLPGVLPALTGVLKTDPKVSSSSALCQCIAIMGNLSAEPTT
RRHMAACEEFGDGCLSLLARCEEDVDLFREVIYTLLGLMMNLCLQAPFVSEVWAVEVSRRCLSLLNSQDGGILTRAAGVLSRTLSSSLKI
VEEALRAGVVKKMMKFLKTGGETASRYAIKILAICTNSYHEAREEVIRLDKRAPTPPLETRLVPGNQSLLVQQAEELGFSILKRMWPGWN

--------------------------------------------------------------
>17019_17019_11_CLDN10-TTC12_CLDN10_chr13_96229592_ENST00000299339_TTC12_chr11_113220795_ENST00000483239_length(transcript)=1652nt_BP=601nt
GGAGAGCGAGCGCGGCTGCAGCCGGCGGCATGGCTAGCACGGCTTCGGAGATCATCGCCTTCATGGTCTCCATCTCAGGCTGGGTACTGG
TGTCCTCCACGCTGCCCACCGACTACTGGAAGGTGTCTACCATCGACGGCACGGTCATCACAACCGCCACCTATTGGGCCAACCTGTGGA
AGGCGTGCGTTACCGACTCCACGGGCGTCTCCAACTGCAAGGACTTCCCCTCCATGCTGGCGCTGGACGGTTATATACAGGCATGTAGAG
GACTTATGATCGCTGCTGTCAGCCTGGGCTTCTTTGGTTCCATATTTGCGCTCTTTGGAATGAAGTGTACCAAAGTCGGAGGCTCCGATA
AAGCCAAAGCTAAAATTGCTTGTTTGGCTGGGATTGTATTCATACTGTCAGGGCTGTGCTCAATGACTGGATGTTCCCTATATGCAAACA
AAATCACAACGGAATTCTTTGATCCTCTCTTTGTTGAGCAAAAGTATGAATTAGGAGCCGCTCTGTTTATTGGATGGGCAGGAGCCTCAC
TGTGCATAATTGGTGGTGTCATATTTTGCTTTTCAATATCTGACAACAACAAAACACCCAGATTATTGGAAGCGCTGGTGTCATTTCTTG
ATTTCTCGGATAAGGAGGCCAACACTGCTATGGGACTGTTCACAGACTTGGCTCTGGAAGAAAGATTCCAAGTCTGGTTCCAGGCCAACC
TTCCAGGTGTTCTCCCTGCACTCACAGGCGTTCTGAAGACAGATCCCAAGGTAAGCAGCTCCTCGGCTCTGTGCCAGTGCATTGCCATCA
TGGGAAACCTCAGTGCTGAGCCCACTACCCGAAGACACATGGCGGCCTGTGAGGAATTTGGGGATGGCTGCTTGAGCCTCCTGGCCAGGT
GTGAGGAGGATGTGGACCTGTTCAGAGAGGTTATCTACACACTCCTGGGACTCATGATGAACCTGTGTCTTCAGGCTCCCTTTGTCTCTG
AGGTTTGGGCTGTGGAGGTGAGCAGAAGGTGCCTGTCTTTACTAAACAGCCAGGATGGAGGAATCCTGACAAGAGCTGCTGGTGTTCTGA
GCCGGACCCTTTCTTCCTCTCTGAAAATTGTTGAGGAGGCCTTGCGAGCAGGAGTGGTAAAGAAAATGATGAAATTCCTGAAGACAGGAG
GTGAGACTGCATCACGTTATGCTATAAAGATACTAGCTATCTGCACGAATAGTTATCATGAAGCTCGGGAAGAAGTAATAAGACTGGATA
AAAAGTTGAGCGTTATGATGAAGCTGCTCAGCTCGGAGGATGAGGTTCTGGTGGGCAACGCTGCCCTCTGCCTTGGTAACTGCATGGAGG
TGCCCAACGTTGCGTCTTCCCTGCTAAAGACGGACCTTTTGCAGGTCTTGTTAAAGCTTGCAGGCAGTGACACACAGAAGACGGCCGTGC
AGGTGAACGCAGGCATTGCTCTGGGGAAGCTGTGCACAGCTGAGCCCAGATTTGCTGCTCAACTGAGAAAGCTTCATGGCCTAGAAATTC
TCAACTCTACGATGAAATACATCAGTGATTCTTGAGAGAGACAGGGTTTGTGTGCATTTGGGGAACACACAGATGCACACCGTGTGTTGT

>17019_17019_11_CLDN10-TTC12_CLDN10_chr13_96229592_ENST00000299339_TTC12_chr11_113220795_ENST00000483239_length(amino acids)=511AA_BP=185
MASTASEIIAFMVSISGWVLVSSTLPTDYWKVSTIDGTVITTATYWANLWKACVTDSTGVSNCKDFPSMLALDGYIQACRGLMIAAVSLG
FFGSIFALFGMKCTKVGGSDKAKAKIACLAGIVFILSGLCSMTGCSLYANKITTEFFDPLFVEQKYELGAALFIGWAGASLCIIGGVIFC
FSISDNNKTPRLLEALVSFLDFSDKEANTAMGLFTDLALEERFQVWFQANLPGVLPALTGVLKTDPKVSSSSALCQCIAIMGNLSAEPTT
RRHMAACEEFGDGCLSLLARCEEDVDLFREVIYTLLGLMMNLCLQAPFVSEVWAVEVSRRCLSLLNSQDGGILTRAAGVLSRTLSSSLKI
VEEALRAGVVKKMMKFLKTGGETASRYAIKILAICTNSYHEAREEVIRLDKKLSVMMKLLSSEDEVLVGNAALCLGNCMEVPNVASSLLK

--------------------------------------------------------------
>17019_17019_12_CLDN10-TTC12_CLDN10_chr13_96229592_ENST00000299339_TTC12_chr11_113220795_ENST00000529221_length(transcript)=1657nt_BP=601nt
GGAGAGCGAGCGCGGCTGCAGCCGGCGGCATGGCTAGCACGGCTTCGGAGATCATCGCCTTCATGGTCTCCATCTCAGGCTGGGTACTGG
TGTCCTCCACGCTGCCCACCGACTACTGGAAGGTGTCTACCATCGACGGCACGGTCATCACAACCGCCACCTATTGGGCCAACCTGTGGA
AGGCGTGCGTTACCGACTCCACGGGCGTCTCCAACTGCAAGGACTTCCCCTCCATGCTGGCGCTGGACGGTTATATACAGGCATGTAGAG
GACTTATGATCGCTGCTGTCAGCCTGGGCTTCTTTGGTTCCATATTTGCGCTCTTTGGAATGAAGTGTACCAAAGTCGGAGGCTCCGATA
AAGCCAAAGCTAAAATTGCTTGTTTGGCTGGGATTGTATTCATACTGTCAGGGCTGTGCTCAATGACTGGATGTTCCCTATATGCAAACA
AAATCACAACGGAATTCTTTGATCCTCTCTTTGTTGAGCAAAAGTATGAATTAGGAGCCGCTCTGTTTATTGGATGGGCAGGAGCCTCAC
TGTGCATAATTGGTGGTGTCATATTTTGCTTTTCAATATCTGACAACAACAAAACACCCAGATTATTGGAAGCGCTGGTGTCATTTCTTG
ATTTCTCGGATAAGGAGGCCAACACTGCTATGGGACTGTTCACAGACTTGGCTCTGGAAGAAAGATTCCAAGTCTGGTTCCAGGCCAACC
TTCCAGGTGTTCTCCCTGCACTCACAGGCGTTCTGAAGACAGATCCCAAGGTAAGCAGCTCCTCGGCTCTGTGCCAGTGCATTGCCATCA
TGGGAAACCTCAGTGCTGAGCCCACTACCCGAAGACACATGGCGGCCTGTGAGGAATTTGGGGATGGCTGCTTGAGCCTCCTGGCCAGGT
GTGAGGAGGATGTGGACCTGTTCAGAGAGGTTATCTACACACTCCTGGGACTCATGATGAACCTGTGTCTTCAGGCTCCCTTTGTCTCTG
AGGTTTGGGCTGTGGAGGTGAGCAGAAGGTGCCTGTCTTTACTAAACAGCCAGGATGGAGGAATCCTGACAAGAGCTGCTGGTGTTCTGA
GCCGGACCCTTTCTTCCTCTCTGAAAATTGTTGAGGAGGCCTTGCGAGCAGGAGTGGTAAAGAAAATGATGAAATTCCTGAAGACAGGAG
GTGAGACTGCATCACGTTATGCTATAAAGATACTAGCTATCTGCACGAATAGTTATCATGAAGCTCGGGAAGAAGTAATAAGACTGGATA
AAAAGTTGAGCGTTATGATGAAGCTGCTCAGCTCGGAGGATGAGGTTCTGGTGGGCAACGCTGCCCTCTGCCTTGGTAACTGCATGGAGG
TGCCCAACGTTGCGTCTTCCCTGCTAAAGACGGACCTTTTGCAGGTCTTGTTAAAGCTTGCAGGCAGTGACACACAGAAGACGGCCGTGC
AGGTGAACGCAGGCATTGCTCTGGGGAAGCTGTGCACAGCTGAGCCCAGATTTGCTGCTCAACTGAGAAAGCTTCATGGCCTAGAAATTC
TCAACTCTACGATGAAATACATCAGTGATTCTTGAGAGAGACAGGGTTTGTGTGCATTTGGGGAACACACAGATGCACACCGTGTGTTGT

>17019_17019_12_CLDN10-TTC12_CLDN10_chr13_96229592_ENST00000299339_TTC12_chr11_113220795_ENST00000529221_length(amino acids)=511AA_BP=185
MASTASEIIAFMVSISGWVLVSSTLPTDYWKVSTIDGTVITTATYWANLWKACVTDSTGVSNCKDFPSMLALDGYIQACRGLMIAAVSLG
FFGSIFALFGMKCTKVGGSDKAKAKIACLAGIVFILSGLCSMTGCSLYANKITTEFFDPLFVEQKYELGAALFIGWAGASLCIIGGVIFC
FSISDNNKTPRLLEALVSFLDFSDKEANTAMGLFTDLALEERFQVWFQANLPGVLPALTGVLKTDPKVSSSSALCQCIAIMGNLSAEPTT
RRHMAACEEFGDGCLSLLARCEEDVDLFREVIYTLLGLMMNLCLQAPFVSEVWAVEVSRRCLSLLNSQDGGILTRAAGVLSRTLSSSLKI
VEEALRAGVVKKMMKFLKTGGETASRYAIKILAICTNSYHEAREEVIRLDKKLSVMMKLLSSEDEVLVGNAALCLGNCMEVPNVASSLLK

--------------------------------------------------------------
>17019_17019_13_CLDN10-TTC12_CLDN10_chr13_96229592_ENST00000376873_TTC12_chr11_113220795_ENST00000314756_length(transcript)=1841nt_BP=796nt
ATATCCGTGTAGAAAATCAGAACGACTCTTTCAGGCCATCTTTAAAATGTCATTGGTAAACCATACTTGATCCTAAATTCCTGTACTTCC
TCAGGCCATCCGAGCATGAAACGCTGTCACCTACCCACATCCGCTGGCTGTGACGCTTGTCAAAGTGTTCTCTATCGGCTGCATGCCTAG
ACCACCAAAGCGTTCTGACCGGACAGTGTCACTGGAGAAGGCGGCGCGACATGTCCAGGGCGCAGATCTGGGCTCTGGTGTCTGGTGTCG
GAGGGTTTGGAGCTCTCGTTGCTGCTACCACGTCCAATGAGTGGAAAGTGACCACGCGAGCCTCCTCGGTGATAACAGCCACTTGGGTTT
ACCAGGGTCTGTGGATGAACTGCGCAGGTAACGCGTTGGGTTCTTTCCATTGCCGACCGCATTTTACTATCTTCAAAGTAGCAGGTTATA
TACAGGCATGTAGAGGACTTATGATCGCTGCTGTCAGCCTGGGCTTCTTTGGTTCCATATTTGCGCTCTTTGGAATGAAGTGTACCAAAG
TCGGAGGCTCCGATAAAGCCAAAGCTAAAATTGCTTGTTTGGCTGGGATTGTATTCATACTGTCAGGGCTGTGCTCAATGACTGGATGTT
CCCTATATGCAAACAAAATCACAACGGAATTCTTTGATCCTCTCTTTGTTGAGCAAAAGTATGAATTAGGAGCCGCTCTGTTTATTGGAT
GGGCAGGAGCCTCACTGTGCATAATTGGTGGTGTCATATTTTGCTTTTCAATATCTGACAACAACAAAACACCCAGATTATTGGAAGCGC
TGGTGTCATTTCTTGATTTCTCGGATAAGGAGGCCAACACTGCTATGGGACTGTTCACAGACTTGGCTCTGGAAGAAAGATTCCAAGTCT
GGTTCCAGGCCAACCTTCCAGGTGTTCTCCCTGCACTCACAGGCGTTCTGAAGACAGATCCCAAGGTAAGCAGCTCCTCGGCTCTGTGCC
AGTGCATTGCCATCATGGGAAACCTCAGTGCTGAGCCCACTACCCGAAGACACATGGCGGCCTGTGAGGAATTTGGGGATGGCTGCTTGA
GCCTCCTGGCCAGGTGTGAGGAGGATGTGGACCTGTTCAGAGAGGTTATCTACACACTCCTGGGACTCATGATGAACCTGTGTCTTCAGG
CTCCCTTTGTCTCTGAGGTTTGGGCTGTGGAGGTGAGCAGAAGGTGCCTGTCTTTACTAAACAGCCAGGATGGAGGAATCCTGACAAGAG
CTGCTGGTGTTCTGAGCCGGACCCTTTCTTCCTCTCTGAAAATTGTTGAGGAGGCCTTGCGAGCAGGAGTGGTAAAGAAAATGATGAAAT
TCCTGAAGACAGGAGGTGAGACTGCATCACGTTATGCTATAAAGATACTAGCTATCTGCACGAATAGTTATCATGAAGCTCGGGAAGAAG
TAATAAGACTGGATAAAAAGTTGAGCGTTATGATGAAGCTGCTCAGCTCGGAGGATGAGGTTCTGGTGGGCAACGCTGCCCTCTGCCTTG
GTAACTGCATGGAGGTGCCCAACGTTGCGTCTTCCCTGCTAAAGACGGACCTTTTGCAGGTCTTGTTAAAGCTTGCAGGCAGTGACACAC
AGAAGACGGCCGTGCAGGTGAACGCAGGCATTGCTCTGGGGAAGCTGTGCACAGCTGAGCCCAGAGTGCCTGCCGAGAGCAGTCATCTCC
AATTTGGAAGAGAGTCTGCTGCACCTGAAGCTCTGTCTCCTCGCAGGTGGGAAGAGATGTTTCACATGCTAGTATTCTCCCTCTCCAGTG

>17019_17019_13_CLDN10-TTC12_CLDN10_chr13_96229592_ENST00000376873_TTC12_chr11_113220795_ENST00000314756_length(amino acids)=565AA_BP=211
MSKCSLSAACLDHQSVLTGQCHWRRRRDMSRAQIWALVSGVGGFGALVAATTSNEWKVTTRASSVITATWVYQGLWMNCAGNALGSFHCR
PHFTIFKVAGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDKAKAKIACLAGIVFILSGLCSMTGCSLYANKITTEFFDPLFVEQ
KYELGAALFIGWAGASLCIIGGVIFCFSISDNNKTPRLLEALVSFLDFSDKEANTAMGLFTDLALEERFQVWFQANLPGVLPALTGVLKT
DPKVSSSSALCQCIAIMGNLSAEPTTRRHMAACEEFGDGCLSLLARCEEDVDLFREVIYTLLGLMMNLCLQAPFVSEVWAVEVSRRCLSL
LNSQDGGILTRAAGVLSRTLSSSLKIVEEALRAGVVKKMMKFLKTGGETASRYAIKILAICTNSYHEAREEVIRLDKKLSVMMKLLSSED
EVLVGNAALCLGNCMEVPNVASSLLKTDLLQVLLKLAGSDTQKTAVQVNAGIALGKLCTAEPRVPAESSHLQFGRESAAPEALSPRRWEE

--------------------------------------------------------------
>17019_17019_14_CLDN10-TTC12_CLDN10_chr13_96229592_ENST00000376873_TTC12_chr11_113220795_ENST00000393020_length(transcript)=1778nt_BP=796nt
ATATCCGTGTAGAAAATCAGAACGACTCTTTCAGGCCATCTTTAAAATGTCATTGGTAAACCATACTTGATCCTAAATTCCTGTACTTCC
TCAGGCCATCCGAGCATGAAACGCTGTCACCTACCCACATCCGCTGGCTGTGACGCTTGTCAAAGTGTTCTCTATCGGCTGCATGCCTAG
ACCACCAAAGCGTTCTGACCGGACAGTGTCACTGGAGAAGGCGGCGCGACATGTCCAGGGCGCAGATCTGGGCTCTGGTGTCTGGTGTCG
GAGGGTTTGGAGCTCTCGTTGCTGCTACCACGTCCAATGAGTGGAAAGTGACCACGCGAGCCTCCTCGGTGATAACAGCCACTTGGGTTT
ACCAGGGTCTGTGGATGAACTGCGCAGGTAACGCGTTGGGTTCTTTCCATTGCCGACCGCATTTTACTATCTTCAAAGTAGCAGGTTATA
TACAGGCATGTAGAGGACTTATGATCGCTGCTGTCAGCCTGGGCTTCTTTGGTTCCATATTTGCGCTCTTTGGAATGAAGTGTACCAAAG
TCGGAGGCTCCGATAAAGCCAAAGCTAAAATTGCTTGTTTGGCTGGGATTGTATTCATACTGTCAGGGCTGTGCTCAATGACTGGATGTT
CCCTATATGCAAACAAAATCACAACGGAATTCTTTGATCCTCTCTTTGTTGAGCAAAAGTATGAATTAGGAGCCGCTCTGTTTATTGGAT
GGGCAGGAGCCTCACTGTGCATAATTGGTGGTGTCATATTTTGCTTTTCAATATCTGACAACAACAAAACACCCAGATTATTGGAAGCGC
TGGTGTCATTTCTTGATTTCTCGGATAAGGAGGCCAACACTGCTATGGGACTGTTCACAGACTTGGCTCTGGAAGAAAGATTCCAAGTCT
GGTTCCAGGCCAACCTTCCAGGTGTTCTCCCTGCACTCACAGGCGTTCTGAAGACAGATCCCAAGGTAAGCAGCTCCTCGGCTCTGTGCC
AGTGCATTGCCATCATGGGAAACCTCAGTGCTGAGCCCACTACCCGAAGACACATGGCGGCCTGTGAGGAATTTGGGGATGGCTGCTTGA
GCCTCCTGGCCAGGTGTGAGGAGGATGTGGACCTGTTCAGAGAGGTTATCTACACACTCCTGGGACTCATGATGAACCTGTGTCTTCAGG
CTCCCTTTGTCTCTGAGGTTTGGGCTGTGGAGGTGAGCAGAAGGTGCCTGTCTTTACTAAACAGCCAGGATGGAGGAATCCTGACAAGAG
CTGCTGGTGTTCTGAGCCGGACCCTTTCTTCCTCTCTGAAAATTGTTGAGGAGGCCTTGCGAGCAGGAGTGGTAAAGAAAATGATGAAAT
TCCTGAAGACAGGAGGTGAGACTGCATCACGTTATGCTATAAAGATACTAGCTATCTGCACGAATAGTTATCATGAAGCTCGGGAAGAAG
TAATAAGACTGGATAAAAGAGCCCCGACACCACCCTTGGAGACACGGCTTGTTCCAGGTAATCAGAGTCTTCTGGTTCAACAAGCAGAGG
AGCTGGGATTTTCCATCCTAAAGAGGATGTGGCCGGGATGGAACTCCATCACCATCCTGAAGCCACAGCAGAGGTGGCAGAATTCTCTGG
GGCCTCATCCAAGTGGCTGTGTATATCAGTAGTTGCTGAGTCCTATTCCATAATACAGCACTATGGTGTGTTTAGCCATTCATTGGTTGA

>17019_17019_14_CLDN10-TTC12_CLDN10_chr13_96229592_ENST00000376873_TTC12_chr11_113220795_ENST00000393020_length(amino acids)=501AA_BP=211
MSKCSLSAACLDHQSVLTGQCHWRRRRDMSRAQIWALVSGVGGFGALVAATTSNEWKVTTRASSVITATWVYQGLWMNCAGNALGSFHCR
PHFTIFKVAGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDKAKAKIACLAGIVFILSGLCSMTGCSLYANKITTEFFDPLFVEQ
KYELGAALFIGWAGASLCIIGGVIFCFSISDNNKTPRLLEALVSFLDFSDKEANTAMGLFTDLALEERFQVWFQANLPGVLPALTGVLKT
DPKVSSSSALCQCIAIMGNLSAEPTTRRHMAACEEFGDGCLSLLARCEEDVDLFREVIYTLLGLMMNLCLQAPFVSEVWAVEVSRRCLSL
LNSQDGGILTRAAGVLSRTLSSSLKIVEEALRAGVVKKMMKFLKTGGETASRYAIKILAICTNSYHEAREEVIRLDKRAPTPPLETRLVP

--------------------------------------------------------------
>17019_17019_15_CLDN10-TTC12_CLDN10_chr13_96229592_ENST00000376873_TTC12_chr11_113220795_ENST00000483239_length(transcript)=1847nt_BP=796nt
ATATCCGTGTAGAAAATCAGAACGACTCTTTCAGGCCATCTTTAAAATGTCATTGGTAAACCATACTTGATCCTAAATTCCTGTACTTCC
TCAGGCCATCCGAGCATGAAACGCTGTCACCTACCCACATCCGCTGGCTGTGACGCTTGTCAAAGTGTTCTCTATCGGCTGCATGCCTAG
ACCACCAAAGCGTTCTGACCGGACAGTGTCACTGGAGAAGGCGGCGCGACATGTCCAGGGCGCAGATCTGGGCTCTGGTGTCTGGTGTCG
GAGGGTTTGGAGCTCTCGTTGCTGCTACCACGTCCAATGAGTGGAAAGTGACCACGCGAGCCTCCTCGGTGATAACAGCCACTTGGGTTT
ACCAGGGTCTGTGGATGAACTGCGCAGGTAACGCGTTGGGTTCTTTCCATTGCCGACCGCATTTTACTATCTTCAAAGTAGCAGGTTATA
TACAGGCATGTAGAGGACTTATGATCGCTGCTGTCAGCCTGGGCTTCTTTGGTTCCATATTTGCGCTCTTTGGAATGAAGTGTACCAAAG
TCGGAGGCTCCGATAAAGCCAAAGCTAAAATTGCTTGTTTGGCTGGGATTGTATTCATACTGTCAGGGCTGTGCTCAATGACTGGATGTT
CCCTATATGCAAACAAAATCACAACGGAATTCTTTGATCCTCTCTTTGTTGAGCAAAAGTATGAATTAGGAGCCGCTCTGTTTATTGGAT
GGGCAGGAGCCTCACTGTGCATAATTGGTGGTGTCATATTTTGCTTTTCAATATCTGACAACAACAAAACACCCAGATTATTGGAAGCGC
TGGTGTCATTTCTTGATTTCTCGGATAAGGAGGCCAACACTGCTATGGGACTGTTCACAGACTTGGCTCTGGAAGAAAGATTCCAAGTCT
GGTTCCAGGCCAACCTTCCAGGTGTTCTCCCTGCACTCACAGGCGTTCTGAAGACAGATCCCAAGGTAAGCAGCTCCTCGGCTCTGTGCC
AGTGCATTGCCATCATGGGAAACCTCAGTGCTGAGCCCACTACCCGAAGACACATGGCGGCCTGTGAGGAATTTGGGGATGGCTGCTTGA
GCCTCCTGGCCAGGTGTGAGGAGGATGTGGACCTGTTCAGAGAGGTTATCTACACACTCCTGGGACTCATGATGAACCTGTGTCTTCAGG
CTCCCTTTGTCTCTGAGGTTTGGGCTGTGGAGGTGAGCAGAAGGTGCCTGTCTTTACTAAACAGCCAGGATGGAGGAATCCTGACAAGAG
CTGCTGGTGTTCTGAGCCGGACCCTTTCTTCCTCTCTGAAAATTGTTGAGGAGGCCTTGCGAGCAGGAGTGGTAAAGAAAATGATGAAAT
TCCTGAAGACAGGAGGTGAGACTGCATCACGTTATGCTATAAAGATACTAGCTATCTGCACGAATAGTTATCATGAAGCTCGGGAAGAAG
TAATAAGACTGGATAAAAAGTTGAGCGTTATGATGAAGCTGCTCAGCTCGGAGGATGAGGTTCTGGTGGGCAACGCTGCCCTCTGCCTTG
GTAACTGCATGGAGGTGCCCAACGTTGCGTCTTCCCTGCTAAAGACGGACCTTTTGCAGGTCTTGTTAAAGCTTGCAGGCAGTGACACAC
AGAAGACGGCCGTGCAGGTGAACGCAGGCATTGCTCTGGGGAAGCTGTGCACAGCTGAGCCCAGATTTGCTGCTCAACTGAGAAAGCTTC
ATGGCCTAGAAATTCTCAACTCTACGATGAAATACATCAGTGATTCTTGAGAGAGACAGGGTTTGTGTGCATTTGGGGAACACACAGATG

>17019_17019_15_CLDN10-TTC12_CLDN10_chr13_96229592_ENST00000376873_TTC12_chr11_113220795_ENST00000483239_length(amino acids)=537AA_BP=211
MSKCSLSAACLDHQSVLTGQCHWRRRRDMSRAQIWALVSGVGGFGALVAATTSNEWKVTTRASSVITATWVYQGLWMNCAGNALGSFHCR
PHFTIFKVAGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDKAKAKIACLAGIVFILSGLCSMTGCSLYANKITTEFFDPLFVEQ
KYELGAALFIGWAGASLCIIGGVIFCFSISDNNKTPRLLEALVSFLDFSDKEANTAMGLFTDLALEERFQVWFQANLPGVLPALTGVLKT
DPKVSSSSALCQCIAIMGNLSAEPTTRRHMAACEEFGDGCLSLLARCEEDVDLFREVIYTLLGLMMNLCLQAPFVSEVWAVEVSRRCLSL
LNSQDGGILTRAAGVLSRTLSSSLKIVEEALRAGVVKKMMKFLKTGGETASRYAIKILAICTNSYHEAREEVIRLDKKLSVMMKLLSSED

--------------------------------------------------------------
>17019_17019_16_CLDN10-TTC12_CLDN10_chr13_96229592_ENST00000376873_TTC12_chr11_113220795_ENST00000529221_length(transcript)=1852nt_BP=796nt
ATATCCGTGTAGAAAATCAGAACGACTCTTTCAGGCCATCTTTAAAATGTCATTGGTAAACCATACTTGATCCTAAATTCCTGTACTTCC
TCAGGCCATCCGAGCATGAAACGCTGTCACCTACCCACATCCGCTGGCTGTGACGCTTGTCAAAGTGTTCTCTATCGGCTGCATGCCTAG
ACCACCAAAGCGTTCTGACCGGACAGTGTCACTGGAGAAGGCGGCGCGACATGTCCAGGGCGCAGATCTGGGCTCTGGTGTCTGGTGTCG
GAGGGTTTGGAGCTCTCGTTGCTGCTACCACGTCCAATGAGTGGAAAGTGACCACGCGAGCCTCCTCGGTGATAACAGCCACTTGGGTTT
ACCAGGGTCTGTGGATGAACTGCGCAGGTAACGCGTTGGGTTCTTTCCATTGCCGACCGCATTTTACTATCTTCAAAGTAGCAGGTTATA
TACAGGCATGTAGAGGACTTATGATCGCTGCTGTCAGCCTGGGCTTCTTTGGTTCCATATTTGCGCTCTTTGGAATGAAGTGTACCAAAG
TCGGAGGCTCCGATAAAGCCAAAGCTAAAATTGCTTGTTTGGCTGGGATTGTATTCATACTGTCAGGGCTGTGCTCAATGACTGGATGTT
CCCTATATGCAAACAAAATCACAACGGAATTCTTTGATCCTCTCTTTGTTGAGCAAAAGTATGAATTAGGAGCCGCTCTGTTTATTGGAT
GGGCAGGAGCCTCACTGTGCATAATTGGTGGTGTCATATTTTGCTTTTCAATATCTGACAACAACAAAACACCCAGATTATTGGAAGCGC
TGGTGTCATTTCTTGATTTCTCGGATAAGGAGGCCAACACTGCTATGGGACTGTTCACAGACTTGGCTCTGGAAGAAAGATTCCAAGTCT
GGTTCCAGGCCAACCTTCCAGGTGTTCTCCCTGCACTCACAGGCGTTCTGAAGACAGATCCCAAGGTAAGCAGCTCCTCGGCTCTGTGCC
AGTGCATTGCCATCATGGGAAACCTCAGTGCTGAGCCCACTACCCGAAGACACATGGCGGCCTGTGAGGAATTTGGGGATGGCTGCTTGA
GCCTCCTGGCCAGGTGTGAGGAGGATGTGGACCTGTTCAGAGAGGTTATCTACACACTCCTGGGACTCATGATGAACCTGTGTCTTCAGG
CTCCCTTTGTCTCTGAGGTTTGGGCTGTGGAGGTGAGCAGAAGGTGCCTGTCTTTACTAAACAGCCAGGATGGAGGAATCCTGACAAGAG
CTGCTGGTGTTCTGAGCCGGACCCTTTCTTCCTCTCTGAAAATTGTTGAGGAGGCCTTGCGAGCAGGAGTGGTAAAGAAAATGATGAAAT
TCCTGAAGACAGGAGGTGAGACTGCATCACGTTATGCTATAAAGATACTAGCTATCTGCACGAATAGTTATCATGAAGCTCGGGAAGAAG
TAATAAGACTGGATAAAAAGTTGAGCGTTATGATGAAGCTGCTCAGCTCGGAGGATGAGGTTCTGGTGGGCAACGCTGCCCTCTGCCTTG
GTAACTGCATGGAGGTGCCCAACGTTGCGTCTTCCCTGCTAAAGACGGACCTTTTGCAGGTCTTGTTAAAGCTTGCAGGCAGTGACACAC
AGAAGACGGCCGTGCAGGTGAACGCAGGCATTGCTCTGGGGAAGCTGTGCACAGCTGAGCCCAGATTTGCTGCTCAACTGAGAAAGCTTC
ATGGCCTAGAAATTCTCAACTCTACGATGAAATACATCAGTGATTCTTGAGAGAGACAGGGTTTGTGTGCATTTGGGGAACACACAGATG

>17019_17019_16_CLDN10-TTC12_CLDN10_chr13_96229592_ENST00000376873_TTC12_chr11_113220795_ENST00000529221_length(amino acids)=537AA_BP=211
MSKCSLSAACLDHQSVLTGQCHWRRRRDMSRAQIWALVSGVGGFGALVAATTSNEWKVTTRASSVITATWVYQGLWMNCAGNALGSFHCR
PHFTIFKVAGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDKAKAKIACLAGIVFILSGLCSMTGCSLYANKITTEFFDPLFVEQ
KYELGAALFIGWAGASLCIIGGVIFCFSISDNNKTPRLLEALVSFLDFSDKEANTAMGLFTDLALEERFQVWFQANLPGVLPALTGVLKT
DPKVSSSSALCQCIAIMGNLSAEPTTRRHMAACEEFGDGCLSLLARCEEDVDLFREVIYTLLGLMMNLCLQAPFVSEVWAVEVSRRCLSL
LNSQDGGILTRAAGVLSRTLSSSLKIVEEALRAGVVKKMMKFLKTGGETASRYAIKILAICTNSYHEAREEVIRLDKKLSVMMKLLSSED

--------------------------------------------------------------

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Fusion Gene PPI Analysis for CLDN10-TTC12

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

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Related Drugs for CLDN10-TTC12

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for CLDN10-TTC12

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner	Gene	Disease ID	Disease name	# pubmeds	Source
Hgene	CLDN10	C4522164	HELIX SYNDROME	3	GENOMICS_ENGLAND;UNIPROT
Tgene		C0001973	Alcoholic Intoxication, Chronic	3	PSYGENET

Fusion Gene Studies in Kim Lab

Fusion gene:CLDN10-TTC12 (FusionGDB2 ID:HG9071TG54970)

Fusion Gene Summary for CLDN10-TTC12

Fusion Gene ORF analysis for CLDN10-TTC12

Fusion Genomic Features for CLDN10-TTC12

Fusion Protein Features for CLDN10-TTC12

Fusion Gene Sequence for CLDN10-TTC12

Fusion Gene PPI Analysis for CLDN10-TTC12

Related Drugs for CLDN10-TTC12

Related Diseases for CLDN10-TTC12

Fusion Gene Studies
in Kim Lab