Fusion Gene Studies
in Kim Lab

FusionBase FusionGDB FusionGDB2 FusionPDB FusionNeoAntigen FusionAI FusionNW FGviewer Publication Contact
FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:ANKRD40-NFIX (FusionGDB2 ID:HG91369TG4784)

Fusion Gene Summary for ANKRD40-NFIX

check button Fusion gene summary
Fusion gene informationFusion gene name: ANKRD40-NFIX
Fusion gene ID: hg91369tg4784
HgeneTgene
Gene symbol

ANKRD40

NFIX

Gene ID

91369

4784

Gene nameankyrin repeat domain 40nuclear factor I X
Synonyms-CTF|MRSHSS|NF-I/X|NF1-X|NF1A|SOTOS2
Cytomap('ANKRD40')('NFIX')

17q21.33

19p13.13

Type of geneprotein-codingprotein-coding
Descriptionankyrin repeat domain-containing protein 40nuclear factor 1 X-typeCCAAT-box-binding transcription factorTGGCA-binding proteinnuclear factor 1/X
Modification date2020031320200329
UniProtAcc

Q6AI12

Q14938

Ensembl transtripts involved in fusion geneENST00000285243, 
Fusion gene scores* DoF score5 X 6 X 4=12022 X 13 X 10=2860
# samples 626
** MAII scorelog2(6/120*10)=-1
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(26/2860*10)=-3.4594316186373
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ANKRD40 [Title/Abstract] AND NFIX [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointANKRD40(48784882)-NFIX(13135835), # samples:3
Anticipated loss of major functional domain due to fusion event.ANKRD40-NFIX seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ANKRD40-NFIX seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ANKRD40-NFIX seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
ANKRD40-NFIX seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneNFIX

GO:0000122

negative regulation of transcription by RNA polymerase II

19706729

TgeneNFIX

GO:0045944

positive regulation of transcription by RNA polymerase II

19706729


check buttonFusion gene breakpoints across ANKRD40 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across NFIX (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4CESCTCGA-C5-A7CM-01AANKRD40chr17

48784882

-NFIXchr19

13135835

+


Top

Fusion Gene ORF analysis for ANKRD40-NFIX

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000285243ENST00000358552ANKRD40chr17

48784882

-NFIXchr19

13135835

+
5CDS-5UTRENST00000285243ENST00000587260ANKRD40chr17

48784882

-NFIXchr19

13135835

+
5CDS-5UTRENST00000285243ENST00000588228ANKRD40chr17

48784882

-NFIXchr19

13135835

+
5CDS-intronENST00000285243ENST00000588680ANKRD40chr17

48784882

-NFIXchr19

13135835

+
In-frameENST00000285243ENST00000360105ANKRD40chr17

48784882

-NFIXchr19

13135835

+
In-frameENST00000285243ENST00000397661ANKRD40chr17

48784882

-NFIXchr19

13135835

+
In-frameENST00000285243ENST00000585575ANKRD40chr17

48784882

-NFIXchr19

13135835

+
In-frameENST00000285243ENST00000587760ANKRD40chr17

48784882

-NFIXchr19

13135835

+
In-frameENST00000285243ENST00000592199ANKRD40chr17

48784882

-NFIXchr19

13135835

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000285243ANKRD40chr1748784882-ENST00000397661NFIXchr1913135835+32904044011702433
ENST00000285243ANKRD40chr1748784882-ENST00000592199NFIXchr1913135835+18864044011885495
ENST00000285243ANKRD40chr1748784882-ENST00000587760NFIXchr1913135835+18474044011702433
ENST00000285243ANKRD40chr1748784882-ENST00000585575NFIXchr1913135835+18864044011885495
ENST00000285243ANKRD40chr1748784882-ENST00000360105NFIXchr1913135835+57624044011579392

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000285243ENST00000397661ANKRD40chr1748784882-NFIXchr1913135835+0.0325958170.9674041
ENST00000285243ENST00000592199ANKRD40chr1748784882-NFIXchr1913135835+0.047600830.95239913
ENST00000285243ENST00000587760ANKRD40chr1748784882-NFIXchr1913135835+0.0435440730.9564559
ENST00000285243ENST00000585575ANKRD40chr1748784882-NFIXchr1913135835+0.047600830.95239913
ENST00000285243ENST00000360105ANKRD40chr1748784882-NFIXchr1913135835+0.0088668490.99113315

Top

Fusion Genomic Features for ANKRD40-NFIX


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
ANKRD40chr1748784881-NFIXchr1913135834+1.43E-101
ANKRD40chr1748784881-NFIXchr1913135834+1.43E-101

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

Top

Fusion Protein Features for ANKRD40-NFIX


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr17:48784882/chr19:13135835)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ANKRD40

Q6AI12

NFIX

Q14938

FUNCTION: Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneANKRD40chr17:48784882chr19:13135835ENST00000285243-159_3844369.0RepeatNote=ANK 1
TgeneNFIXchr17:48784882chr19:13135835ENST000005855750111_1941495.0DNA bindingCTF/NF-I
TgeneNFIXchr17:48784882chr19:13135835ENST00000587260091_1940281.6666666666667DNA bindingCTF/NF-I
TgeneNFIXchr17:48784882chr19:13135835ENST000005877600101_1941460.6666666666667DNA bindingCTF/NF-I
TgeneNFIXchr17:48784882chr19:13135835ENST00000397661010398_4069878.6666666666666Motif9aaTAD
TgeneNFIXchr17:48784882chr19:13135835ENST00000585575011398_4061495.0Motif9aaTAD
TgeneNFIXchr17:48784882chr19:13135835ENST0000058726009398_4060281.6666666666667Motif9aaTAD
TgeneNFIXchr17:48784882chr19:13135835ENST00000587760010398_4061460.6666666666667Motif9aaTAD
TgeneNFIXchr17:48784882chr19:13135835ENST00000592199011398_4069503.0Motif9aaTAD

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneANKRD40chr17:48784882chr19:13135835ENST00000285243-15148_24744369.0Compositional biasNote=Pro-rich
HgeneANKRD40chr17:48784882chr19:13135835ENST00000285243-1599_10644369.0Compositional biasNote=Poly-Asp
HgeneANKRD40chr17:48784882chr19:13135835ENST00000285243-1543_7244369.0RepeatNote=ANK 2
TgeneNFIXchr17:48784882chr19:13135835ENST000003976610101_1949878.6666666666666DNA bindingCTF/NF-I
TgeneNFIXchr17:48784882chr19:13135835ENST000005921990111_1949503.0DNA bindingCTF/NF-I


Top

Fusion Gene Sequence for ANKRD40-NFIX


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>4727_4727_1_ANKRD40-NFIX_ANKRD40_chr17_48784882_ENST00000285243_NFIX_chr19_13135835_ENST00000360105_length(transcript)=5762nt_BP=404nt
TTGTCACACTGAACAGGGTCCCCCGGAGCCGGCCTTCGGGAGGCGCGGCCCGGGAGGAGGCCTGGGCCTGCGGGCCGGGAGCAGCAGGGG
CGGCCCGCGGGAGGGAGCGGAAGTCCCGGGGCGGGCGCGGGCAGCGGCGCGAGCAGGGCGGGCGAGTTCCGCGCTCCCTCCCCATGGCCG
GGAGCGGGCCGCGGCGACGGCGGCGGCGCTGACAGGCCCCGGGCGGGGCGGGGCAGGCGGGCCTGGGCGGGGGCCTGGGGCTGTGGGAAG
ATGAACGCCCTCCTAGAGCAGAAGGAGCAGCAGGAGAGGCTGCGGGAGGCCGCGGCCTTAGGGGACATTCGGGAGGTGCAGAAACTGGTG
GAGAGCGGGGTGGATGTGAACTCCCAAAATGAGGTCAACGGCTGGATGAGTTCCACCCGTTCATCGAGGCACTGCTGCCTCACGTCCGCG
CTTTCTCCTACACCTGGTTCAACCTGCAGGCGCGGAAGCGCAAGTACTTCAAGAAGCATGAAAAGCGGATGTCGAAGGACGAGGAGCGGG
CGGTGAAGGACGAGCTGCTGGGCGAGAAGCCCGAGATCAAGCAGAAGTGGGCATCCCGGCTGCTGGCCAAGCTGCGCAAGGACATCCGGC
CCGAGTTCCGCGAGGACTTCGTGCTGACCATCACGGGCAAGAAGCCCCCCTGCTGCGTGCTCTCCAACCCCGACCAGAAGGGCAAGATCC
GGCGGATTGACTGCCTGCGCCAGGCTGACAAGGTGTGGCGGCTGGACCTGGTCATGGTGATTTTGTTTAAGGGGATCCCCCTGGAAAGTA
CTGATGGGGAGCGGCTCTACAAGTCGCCTCAGTGCTCGAACCCCGGCCTGTGCGTCCAGCCACATCACATTGGAGTCACAATCAAAGAAC
TGGATCTTTATCTGGCTTACTTTGTCCACACTCCGGAATCCGGACAATCAGATAGTTCAAACCAGCAAGGAGATGCGGACATCAAACCAC
TGCCCAACGGGCACTTAAGTTTCCAGGACTGTTTTGTGACTTCCGGGGTCTGGAATGTGACGGAGCTGGTGAGAGTATCACAGACTCCTG
TTGCAACAGCATCAGGGCCCAACTTCTCCCTGGCGGACCTGGAGAGTCCCAGCTACTACAACATCAACCAGGTGACCCTGGGGCGGCGGT
CCATCACCTCCCCTCCTTCCACCAGCACCACCAAGCGCCCCAAGTCCATCGATGACAGTGAGATGGAGAGCCCTGTTGATGACGTGTTCT
ATCCCGGGACAGGCCGTTCCCCAGCAGCTGGCAGCAGCCAGTCCAGCGGGTGGCCCAACGATGTGGATGCAGGGAGCCCCCGGGCCACAG
CATCAGCCCTGCACTTCCCCTCCACGTCCATCATCCAGCAGTCGAGCCCGTATTTCACGCACCCGACCATCCGCTACCACCACCACCACG
GGCAGGACTCACTGAAGGAGTTTGTGCAGTTTGTGTGCTCGGATGGCTCGGGCCAGGCCACCGGACAGCATTCGCAACGACAGGCGCCTC
CTCTGCCAACCGGTTTGTCAGCATCGGACCCCGGGACGGCAACTTTCTGAACATCCCACAGCAGTCTCAGTCCTGGTTCCTCTGATAAGA
TCGACAAAAGAAACAACAAAATGAGAAGAAGAGGTTCCTCGAAAGGGGGGAGAAGAAATTTTGAGAATGGAAAAATCCCCCAGCCCAGCC
CAGCCCCACCGAAAAGCAAAAATTACACGTCGTCAGCCACTCAGCCCTTCTCTCCTCCAGCCCGGGGACCCCCGCGGGCCCCAGAAGCAG
CCCAGTTCTCAGAGAGCCCTTGGAAGGGGTCTCGGTGGAGCTGTGCACCAGCAGCCAAGCAGAAAGAAACACGCGACATGGACTCTGTCA
AGTAGAGGACAGAAAGCAAGAAAGGATGCAGAACTGCCTTCCTCCCCCTGACCCCGCCCCGGCCTTCTGGGGAAGGAACAAAGTCCCCAA
ACAAAGCAACCAGCACAATTCTGAAGGGGCCTGGCCTCCACCCTCACCCCTTCCTAGGGGAACCCCACCCTCCACACAGCCGGAGCTGCC
CTAGGGAGCCTGGAGGGCCAGCTTGTAAAGATGATGGGGTTTAGATCCCTCAGGCTCTCCCCTCCAGACTCCGCCCTTCCCTCCCTCCCT
CCCTCCCTCCCTCTCTGCCAAGGCTCCAGCTTCTTCCCCCAGCTGCTCCCGACCAGGAGGGGGAGAGCAGCCTCCACTTACCCCACCCCA
CCCTTGGGCTAAAAGCCCCCAGGCGGGCAGGGGGTGACCCCTGGAGCTAGTTGCGTGTCCCAGAATGGAGGGTGTTCTGACACCCCACCC
TGAGCCGCAAGAGCAGTCCTGGGGCCCTGGACCCCTCTGTACAGTCCGTAGGAAAAAGTCGGAATGCTCTCGACGGCCTCGTCCCAGCCT
GGGACAGGCCCCCTTTCCCCTCTCTCTGCAGGCCAGGAGGGCCTCCTTCCTGCCACGAGGGAGGGGAGTCGGGCCCCAGGTCGCCCCCGC
CCCCAGCCCTGCATGCAGGTGCCCTCGCTCCGCCCCATCAGTTCCTGCCCCTGCCCCTCATGCAGACTGCCCTGCTGGGGCCGGGCCGGA
GGGTGGAGCAGAAAGGGGACCCCGGAGCCGAGCGAGGAGGACCAGGCAGCCGCCGCTGCCGCGCTAAGCCACCACCTGCGCTTAGGTAGG
CGTCCTGCTCGCCGACTTTCAGTTCCTTGGGAGGGTGTTGGGTGTCGTCCTTTTCAAAAGTGTTTTGGAGCTTTCTGTGCCCCCCGACTT
TCCCCCGCCTCCCCGCCCCCCACGTGGCCACTTTTCTCTGGATTTTAGCTGTAATGTCTTTACTCTTTATTTAGGGGTGGGGCATTCATT
GTTTGGGTCTTTTGCTGTTGGAATGGGAACTCCTCCTCCATTTGAGCAACTTGGGAACAATTTGGTAACACACCACAGGAAGTAGCTCTC
CCCCCCAGCCCCCTCCTCCCTCAAGGGAGGGTTGGGGGGCCTGTCCAGAGGGTCTTCAGAAGCCCCCCTGGGAGGGAGGGGAGGATGAGC
ACGCCCAGCTCCCCTCCAGGGTGTGACTTGGCCCCTCTGGCTTGTCTTTCTGTGCCTTACTCCTCCTCCTGCGTCTCCCGTTCCTGGCCC
CTTCTTGAGTCCTTGTGCCTCTCTCTTTCTCTCTCTTTCTTAATTGTATGAAAACACAAAGCACAGGTCAGGATCCTCTGAGAGAAAATC
AACATTGCACCACGTAGGGGTGGGCTATGGGCTGTATTTATTGTGAATCTAGTTTGTGAGGCTGTGGCCCCGAGCTGGCGGAGGGAGGGA
AGAGGAGGGAGTGACGGGAGGGGAGGAGGTCAGCGACCTGGGGCCGTAGCGGCAGGCGAACGGTGCCTGCTACCCAGCTGGAAGCCACAA
GGTGGCTGGCTCCAGGGGCGGCTTTTGTTGGAAGTTGAGTGAAGCCCTCCCCCTGTCCTCAGCGTGCAGCCCTAGAGGACCCCAGGGCTG
AGGGGCAGTGGATCCTGCGGGAGTCTCCCGGGGCGTGGGGAGTAAGGCCCCGGGGGTGGGGGGCCGGGTGGGCCGGGCGTGACGCGCGGT
CAAAGTGCAATGATTTTTCAGTTCGGTTGGCTAAACAGGGTCAGAGCTGAGAGCGAAGCAGAAGGGGCTCCCTGTCCGGCCCACGTGCCC
TTTCCCTCGACGACAGTCGAGGGCTCGGGCTCTGTGGGACTGTGGGAGCTAGGGTCTGCGGGGCGCCTGCCCGGGCGAGGTCGGAAGCTG
CAGGCCAGCTGGGCCCGGGCCGGAGCGTGCCCGGCGGGGCTGCCCGGGCGGGCAGGGGGTGGGGGCTGCTCCTTTCCCAAGTGGTGTTGT
GAGGGGCAATGAGGGCAACAGGAGATGTGGGGACGTGTTAGGAGAGAAAAAAAAAAAAACAAAAATATATATGGGGGAAATTAACTTTTT
TTTTTCATTGAACCAAGTGCAATGCATCAGAGAGTTTTCCTATCTTTGTATGTTAAGAGATTAAGAAAAAAAAATTCTATTTTTGTTGTA
ATGTCCTCGCGGCTCTGGGGACGCTAAAAGAACCGGGCCTGCCCCGCCCTGCGCGGGGATAACGAAAGCTGAGTGTTTTTCCCTTTTTTT
TGTTCGTTTTTAGTTTTTTTTTTTTTAAGTCGTTTTCCTGCGTTGACGAGGATGATCTGGGGTTTTTATTTGTTTCGTCGTTCGTTCTGT
TTCGGTGGGAGGGCTGAAGGAAACGTTCACATTTTAGAGTTTAAAAAAAACACCTCGACATTTAAAAAATCAACCAACACAAGATCAAAA
AGGAAAAGGACGAGAGAAAAATTATTTTTAAGATAATTAAACATAAAACCCTGGTGCTTCTTACATTATAAAGTACGTTTTAAAGAACCC
ACAAACTATTATACATAAGTTTATGAATCAATTAAATATCCTGCACTTGTTAGGAATACGCATATCCCTTCTTTGTTGAGTTTAACGGAA
CGGGACAGCGGCGTGCCCCCGGCGGCTGGACTGCTCCGGCCGCGGGTCTCCCCGGGCGCCCCTCCCTGGGGCCCAGCACCCCTCCTCGCC
CCATCCCCGTCCGGGTACGGGGGCGCGGCAGGGGTCCCCGGCCCCTCCCCCGCAGAGGTCAATGCCAACGAACAAACGTCCCCTCCCTCC
CTCCCTCTCCGCCCCGAGCGCCCTTCTTTGAGCCAGACGCCAACTTGACCCTCACCAGCATTATCAGGAGCGCGCTCAGCAAGTTGGTAG
TTTCCTCCCCCCTTTCCCGGCGCCCCTCCCGCCCCCATTCAACATCTCTCATCCTATCCCCGACCCCCTCCGGGGAACACCGGGAAGGCT
CGACGCTCCAGGACAGGACCAGCCACGCAGACAGGTCGATTTGCCCAGGCCCGCGCCCGCACGCACGCACGCACACGGCCCCGCACACAG
CCCCGCCCCACCCCGCAACCAGCCCTGTCGACTGCCTTATACACCCGCCCCCGCGCTGGCCGGCCGACCTAGTGCCTTGTTCTCACCCCC
GTGCTGGCGGAGCGGACGCCGCGCTCTGGGTCCCAGAGGGGCCGGGTGGCTCAGACGACCCACCACTCCCCCACCCTGACCGTGCTGAAC
AGACCCCCCCACACGAGAGAAAATAAAGGAGCAATAAAGTCACGAGAACTTTCGTCCCCCAATCGAGAGCCCGAGGGGCACCCCAGCCCC
GCCTCTGCTCCCCCCCACCCCACCCACCCTCGGGGCGCCCCCCTCCCCCCGCAAGCCAGCCTGGGCCAGCCCCGCTTCGGCCCCTCCCGG
GAGATCCGTGCGCCCGACCAGCACCAGCATCGCGGACCGCAAAGGCCGCCCGTCCCGTCAAACAAGTTTCTTCTTAGGCTAAGAAACGCA
GTATATACGAGTATCTCTATATATAGTACTAATGGATTTGGTGTGCTTCCCCCTTAGCGTCCCCCTCCCTCTGCTCCTCCTCCTTCAGCC
TGGTCTCCCCCTCTTCTCTGCCCTCCACCCCCGTCTCTGCACTGAGATACATAAGAAACAAGGGTAGTTTACTGTCTGTTTTGTTTTCTG
GGTTTTCAGTGTCCTAGCGGAATGCAAGTAGGCAGCCAGCCCGTCTGTTCCCTCTCCGCCCCGCCCCGCCCCGCCCCCGTCACTGCGCTT
CTGTTATACCATCTTTGCCTGACTCTCTCCGGCTTCTCCATTGAATGGCTAATGTGTATGTGAAATAAAGAAATAAAGAAAAACAAACGC

>4727_4727_1_ANKRD40-NFIX_ANKRD40_chr17_48784882_ENST00000285243_NFIX_chr19_13135835_ENST00000360105_length(amino acids)=392AA_BP=1
MDEFHPFIEALLPHVRAFSYTWFNLQARKRKYFKKHEKRMSKDEERAVKDELLGEKPEIKQKWASRLLAKLRKDIRPEFREDFVLTITGK
KPPCCVLSNPDQKGKIRRIDCLRQADKVWRLDLVMVILFKGIPLESTDGERLYKSPQCSNPGLCVQPHHIGVTIKELDLYLAYFVHTPES
GQSDSSNQQGDADIKPLPNGHLSFQDCFVTSGVWNVTELVRVSQTPVATASGPNFSLADLESPSYYNINQVTLGRRSITSPPSTSTTKRP
KSIDDSEMESPVDDVFYPGTGRSPAAGSSQSSGWPNDVDAGSPRATASALHFPSTSIIQQSSPYFTHPTIRYHHHHGQDSLKEFVQFVCS

--------------------------------------------------------------
>4727_4727_2_ANKRD40-NFIX_ANKRD40_chr17_48784882_ENST00000285243_NFIX_chr19_13135835_ENST00000397661_length(transcript)=3290nt_BP=404nt
TTGTCACACTGAACAGGGTCCCCCGGAGCCGGCCTTCGGGAGGCGCGGCCCGGGAGGAGGCCTGGGCCTGCGGGCCGGGAGCAGCAGGGG
CGGCCCGCGGGAGGGAGCGGAAGTCCCGGGGCGGGCGCGGGCAGCGGCGCGAGCAGGGCGGGCGAGTTCCGCGCTCCCTCCCCATGGCCG
GGAGCGGGCCGCGGCGACGGCGGCGGCGCTGACAGGCCCCGGGCGGGGCGGGGCAGGCGGGCCTGGGCGGGGGCCTGGGGCTGTGGGAAG
ATGAACGCCCTCCTAGAGCAGAAGGAGCAGCAGGAGAGGCTGCGGGAGGCCGCGGCCTTAGGGGACATTCGGGAGGTGCAGAAACTGGTG
GAGAGCGGGGTGGATGTGAACTCCCAAAATGAGGTCAACGGCTGGATGAGTTCCACCCGTTCATCGAGGCACTGCTGCCTCACGTCCGCG
CTTTCTCCTACACCTGGTTCAACCTGCAGGCGCGGAAGCGCAAGTACTTCAAGAAGCATGAAAAGCGGATGTCGAAGGACGAGGAGCGGG
CGGTGAAGGACGAGCTGCTGGGCGAGAAGCCCGAGATCAAGCAGAAGTGGGCATCCCGGCTGCTGGCCAAGCTGCGCAAGGACATCCGGC
CCGAGTTCCGCGAGGACTTCGTGCTGACCATCACGGGCAAGAAGCCCCCCTGCTGCGTGCTCTCCAACCCCGACCAGAAGGGCAAGATCC
GGCGGATTGACTGCCTGCGCCAGGCTGACAAGGTGTGGCGGCTGGACCTGGTCATGGTGATTTTGTTTAAGGGGATCCCCCTGGAAAGTA
CTGATGGGGAGCGGCTCTACAAGTCGCCTCAGTGCTCGAACCCCGGCCTGTGCGTCCAGCCACATCACATTGGAGTCACAATCAAAGAAC
TGGATCTTTATCTGGCTTACTTTGTCCACACTCCGGAATCCGGACAATCAGATAGTTCAAACCAGCAAGGAGATGCGGACATCAAACCAC
TGCCCAACGGGCACTTAAGTTTCCAGGACTGTTTTGTGACTTCCGGGGTCTGGAATGTGACGGAGCTGGTGAGAGTATCACAGACTCCTG
TTGCAACAGCATCAGGGCCCAACTTCTCCCTGGCGGACCTGGAGAGTCCCAGCTACTACAACATCAACCAGGTGACCCTGGGGCGGCGGT
CCATCACCTCCCCTCCTTCCACCAGCACCACCAAGCGCCCCAAGTCCATCGATGACAGTGAGATGGAGAGCCCTGTTGATGACGTGTTCT
ATCCCGGGACAGGCCGTTCCCCAGCAGCTGGCAGCAGCCAGTCCAGCGGGTGGCCCAACGATGTGGATGCAGGCCCGGCTTCTCTAAAGA
AGTCAGGAAAGCTGGACTTCTGCAGTGCCCTCTCCTCTCAGGGCAGCTCCCCGCGCATGGCTTTCACCCACCACCCGCTGCCTGTGCTTG
CTGGAGTCAGACCAGGGAGCCCCCGGGCCACAGCATCAGCCCTGCACTTCCCCTCCACGTCCATCATCCAGCAGTCGAGCCCGTATTTCA
CGCACCCGACCATCCGCTACCACCACCACCACGGGCAGGACTCACTGAAGGAGTTTGTGCAGTTTGTGTGCTCGGATGGCTCGGGCCAGG
CCACCGGACAGCATTCGCAACGACAGGCGCCTCCTCTGCCAACCGGTTTGTCAGCATCGGACCCCGGGACGGCAACTTTCTGAACATCCC
ACAGCAGTCTCAGTCCTGGTTCCTCTGATAAGATCGACAAAAGAAACAACAAAATGAGAAGAAGAGGTTCCTCGAAAGGGGGGAGAAGAA
ATTTTGAGAATGGAAAAATCCCCCAGCCCAGCCCAGCCCCACCGAAAAGCAAAAATTACACGTCGTCAGCCACTCAGCCCTTCTCTCCTC
CAGCCCGGGGACCCCCGCGGGCCCCAGAAGCAGCCCAGTTCTCAGAGAGCCCTTGGAAGGGGTCTCGGTGGAGCTGTGCACCAGCAGCCA
AGCAGAAAGAAACACGCGACATGGACTCTGTCAAGTAGAGGACAGAAAGCAAGAAAGGATGCAGAACTGCCTTCCTCCCCCTGACCCCGC
CCCGGCCTTCTGGGGAAGGAACAAAGTCCCCAAACAAAGCAACCAGCACAATTCTGAAGGGGCCTGGCCTCCACCCTCACCCCTTCCTAG
GGGAACCCCACCCTCCACACAGCCGGAGCTGCCCTAGGGAGCCTGGAGGGCCAGCTTGTAAAGATGATGGGGTTTAGATCCCTCAGGCTC
TCCCCTCCAGACTCCGCCCTTCCCTCCCTCCCTCCCTCCCTCCCTCTCTGCCAAGGCTCCAGCTTCTTCCCCCAGCTGCTCCCGACCAGG
AGGGGGAGAGCAGCCTCCACTTACCCCACCCCACCCTTGGGCTAAAAGCCCCCAGGCGGGCAGGGGGTGACCCCTGGAGCTAGTTGCGTG
TCCCAGAATGGAGGGTGTTCTGACACCCCACCCTGAGCCGCAAGAGCAGTCCTGGGGCCCTGGACCCCTCTGTACAGTCCGTAGGAAAAA
GTCGGAATGCTCTCGACGGCCTCGTCCCAGCCTGGGACAGGCCCCCTTTCCCCTCTCTCTGCAGGCCAGGAGGGCCTCCTTCCTGCCACG
AGGGAGGGGAGTCGGGCCCCAGGTCGCCCCCGCCCCCAGCCCTGCATGCAGGTGCCCTCGCTCCGCCCCATCAGTTCCTGCCCCTGCCCC
TCATGCAGACTGCCCTGCTGGGGCCGGGCCGGAGGGTGGAGCAGAAAGGGGACCCCGGAGCCGAGCGAGGAGGACCAGGCAGCCGCCGCT
GCCGCGCTAAGCCACCACCTGCGCTTAGGTAGGCGTCCTGCTCGCCGACTTTCAGTTCCTTGGGAGGGTGTTGGGTGTCGTCCTTTTCAA
AAGTGTTTTGGAGCTTTCTGTGCCCCCCGACTTTCCCCCGCCTCCCCGCCCCCCACGTGGCCACTTTTCTCTGGATTTTAGCTGTAATGT
CTTTACTCTTTATTTAGGGGTGGGGCATTCATTGTTTGGGTCTTTTGCTGTTGGAATGGGAACTCCTCCTCCATTTGAGCAACTTGGGAA
CAATTTGGTAACACACCACAGGAAGTAGCTCTCCCCCCCAGCCCCCTCCTCCCTCAAGGGAGGGTTGGGGGGCCTGTCCAGAGGGTCTTC
AGAAGCCCCCCTGGGAGGGAGGGGAGGATGAGCACGCCCAGCTCCCCTCCAGGGTGTGACTTGGCCCCTCTGGCTTGTCTTTCTGTGCCT

>4727_4727_2_ANKRD40-NFIX_ANKRD40_chr17_48784882_ENST00000285243_NFIX_chr19_13135835_ENST00000397661_length(amino acids)=433AA_BP=1
MDEFHPFIEALLPHVRAFSYTWFNLQARKRKYFKKHEKRMSKDEERAVKDELLGEKPEIKQKWASRLLAKLRKDIRPEFREDFVLTITGK
KPPCCVLSNPDQKGKIRRIDCLRQADKVWRLDLVMVILFKGIPLESTDGERLYKSPQCSNPGLCVQPHHIGVTIKELDLYLAYFVHTPES
GQSDSSNQQGDADIKPLPNGHLSFQDCFVTSGVWNVTELVRVSQTPVATASGPNFSLADLESPSYYNINQVTLGRRSITSPPSTSTTKRP
KSIDDSEMESPVDDVFYPGTGRSPAAGSSQSSGWPNDVDAGPASLKKSGKLDFCSALSSQGSSPRMAFTHHPLPVLAGVRPGSPRATASA

--------------------------------------------------------------
>4727_4727_3_ANKRD40-NFIX_ANKRD40_chr17_48784882_ENST00000285243_NFIX_chr19_13135835_ENST00000585575_length(transcript)=1886nt_BP=404nt
TTGTCACACTGAACAGGGTCCCCCGGAGCCGGCCTTCGGGAGGCGCGGCCCGGGAGGAGGCCTGGGCCTGCGGGCCGGGAGCAGCAGGGG
CGGCCCGCGGGAGGGAGCGGAAGTCCCGGGGCGGGCGCGGGCAGCGGCGCGAGCAGGGCGGGCGAGTTCCGCGCTCCCTCCCCATGGCCG
GGAGCGGGCCGCGGCGACGGCGGCGGCGCTGACAGGCCCCGGGCGGGGCGGGGCAGGCGGGCCTGGGCGGGGGCCTGGGGCTGTGGGAAG
ATGAACGCCCTCCTAGAGCAGAAGGAGCAGCAGGAGAGGCTGCGGGAGGCCGCGGCCTTAGGGGACATTCGGGAGGTGCAGAAACTGGTG
GAGAGCGGGGTGGATGTGAACTCCCAAAATGAGGTCAACGGCTGGATGAGTTCCACCCGTTCATCGAGGCACTGCTGCCTCACGTCCGCG
CTTTCTCCTACACCTGGTTCAACCTGCAGGCGCGGAAGCGCAAGTACTTCAAGAAGCATGAAAAGCGGATGTCGAAGGACGAGGAGCGGG
CGGTGAAGGACGAGCTGCTGGGCGAGAAGCCCGAGATCAAGCAGAAGTGGGCATCCCGGCTGCTGGCCAAGCTGCGCAAGGACATCCGGC
CCGAGTTCCGCGAGGACTTCGTGCTGACCATCACGGGCAAGAAGCCCCCCTGCTGCGTGCTCTCCAACCCCGACCAGAAGGGCAAGATCC
GGCGGATTGACTGCCTGCGCCAGGCTGACAAGGTGTGGCGGCTGGACCTGGTCATGGTGATTTTGTTTAAGGGGATCCCCCTGGAAAGTA
CTGATGGGGAGCGGCTCTACAAGTCGCCTCAGTGCTCGAACCCCGGCCTGTGCGTCCAGCCACATCACATTGGAGTCACAATCAAAGAAC
TGGATCTTTATCTGGCTTACTTTGTCCACACTCCGGAATCCGGACAATCAGATAGTTCAAACCAGCAAGGAGATGCGGACATCAAACCAC
TGCCCAACGGGCACTTAAGTTTCCAGGACTGTTTTGTGACTTCCGGGGTCTGGAATGTGACGGAGCTGGTGAGAGTATCACAGACTCCTG
TTGCAACAGCATCAGGGCCCAACTTCTCCCTGGCGGACCTGGAGAGTCCCAGCTACTACAACATCAACCAGGTGACCCTGGGGCGGCGGT
CCATCACCTCCCCTCCTTCCACCAGCACCACCAAGCGCCCCAAGTCCATCGATGACAGTGAGATGGAGAGCCCTGTTGATGACGTGTTCT
ATCCCGGGACAGGCCGTTCCCCAGCAGCTGGCAGCAGCCAGTCCAGCGGGTGGCCCAACGATGTGGATGCAGGCCCGGCTTCTCTAAAGA
AGTCAGGAAAGCTGGACTTCTGCAGTGCCCTCTCCTCTCAGGGCAGCTCCCCGCGCATGGCTTTCACCCACCACCCGCTGCCTGTGCTTG
CTGGAGTCAGACCAGGGAGCCCCCGGGCCACAGCATCAGCCCTGCACTTCCCCTCCACGTCCATCATCCAGCAGTCGAGCCCGTATTTCA
CGCACCCGACCATCCGCTACCACCACCACCACGGGCAGGACTCACTGAAGGAGTTTGTGCAGTTTGTGTGCTCGGATGGCTCGGGCCAGG
CCACCGGACAGCCCAACGGTAGCGGCCAGGGCAAAGTCCCGGGGTCATTTTTGCTACCGCCGCCGCCTCCAGTGGCCAGACCTGTGCCCC
TTCCTATGCCTGATTCCAAATCCACCAGCACTGCCCCAGACGGCGCCGCCTTGACTCCTCCATCACCTTCATTCGCAACGACAGGCGCCT

>4727_4727_3_ANKRD40-NFIX_ANKRD40_chr17_48784882_ENST00000285243_NFIX_chr19_13135835_ENST00000585575_length(amino acids)=495AA_BP=1
MDEFHPFIEALLPHVRAFSYTWFNLQARKRKYFKKHEKRMSKDEERAVKDELLGEKPEIKQKWASRLLAKLRKDIRPEFREDFVLTITGK
KPPCCVLSNPDQKGKIRRIDCLRQADKVWRLDLVMVILFKGIPLESTDGERLYKSPQCSNPGLCVQPHHIGVTIKELDLYLAYFVHTPES
GQSDSSNQQGDADIKPLPNGHLSFQDCFVTSGVWNVTELVRVSQTPVATASGPNFSLADLESPSYYNINQVTLGRRSITSPPSTSTTKRP
KSIDDSEMESPVDDVFYPGTGRSPAAGSSQSSGWPNDVDAGPASLKKSGKLDFCSALSSQGSSPRMAFTHHPLPVLAGVRPGSPRATASA
LHFPSTSIIQQSSPYFTHPTIRYHHHHGQDSLKEFVQFVCSDGSGQATGQPNGSGQGKVPGSFLLPPPPPVARPVPLPMPDSKSTSTAPD

--------------------------------------------------------------
>4727_4727_4_ANKRD40-NFIX_ANKRD40_chr17_48784882_ENST00000285243_NFIX_chr19_13135835_ENST00000587760_length(transcript)=1847nt_BP=404nt
TTGTCACACTGAACAGGGTCCCCCGGAGCCGGCCTTCGGGAGGCGCGGCCCGGGAGGAGGCCTGGGCCTGCGGGCCGGGAGCAGCAGGGG
CGGCCCGCGGGAGGGAGCGGAAGTCCCGGGGCGGGCGCGGGCAGCGGCGCGAGCAGGGCGGGCGAGTTCCGCGCTCCCTCCCCATGGCCG
GGAGCGGGCCGCGGCGACGGCGGCGGCGCTGACAGGCCCCGGGCGGGGCGGGGCAGGCGGGCCTGGGCGGGGGCCTGGGGCTGTGGGAAG
ATGAACGCCCTCCTAGAGCAGAAGGAGCAGCAGGAGAGGCTGCGGGAGGCCGCGGCCTTAGGGGACATTCGGGAGGTGCAGAAACTGGTG
GAGAGCGGGGTGGATGTGAACTCCCAAAATGAGGTCAACGGCTGGATGAGTTCCACCCGTTCATCGAGGCACTGCTGCCTCACGTCCGCG
CTTTCTCCTACACCTGGTTCAACCTGCAGGCGCGGAAGCGCAAGTACTTCAAGAAGCATGAAAAGCGGATGTCGAAGGACGAGGAGCGGG
CGGTGAAGGACGAGCTGCTGGGCGAGAAGCCCGAGATCAAGCAGAAGTGGGCATCCCGGCTGCTGGCCAAGCTGCGCAAGGACATCCGGC
CCGAGTTCCGCGAGGACTTCGTGCTGACCATCACGGGCAAGAAGCCCCCCTGCTGCGTGCTCTCCAACCCCGACCAGAAGGGCAAGATCC
GGCGGATTGACTGCCTGCGCCAGGCTGACAAGGTGTGGCGGCTGGACCTGGTCATGGTGATTTTGTTTAAGGGGATCCCCCTGGAAAGTA
CTGATGGGGAGCGGCTCTACAAGTCGCCTCAGTGCTCGAACCCCGGCCTGTGCGTCCAGCCACATCACATTGGAGTCACAATCAAAGAAC
TGGATCTTTATCTGGCTTACTTTGTCCACACTCCGGAATCCGGACAATCAGATAGTTCAAACCAGCAAGGAGATGCGGACATCAAACCAC
TGCCCAACGGGCACTTAAGTTTCCAGGACTGTTTTGTGACTTCCGGGGTCTGGAATGTGACGGAGCTGGTGAGAGTATCACAGACTCCTG
TTGCAACAGCATCAGGGCCCAACTTCTCCCTGGCGGACCTGGAGAGTCCCAGCTACTACAACATCAACCAGGTGACCCTGGGGCGGCGGT
CCATCACCTCCCCTCCTTCCACCAGCACCACCAAGCGCCCCAAGTCCATCGATGACAGTGAGATGGAGAGCCCTGTTGATGACGTGTTCT
ATCCCGGGACAGGCCGTTCCCCAGCAGCTGGCAGCAGCCAGTCCAGCGGGTGGCCCAACGATGTGGATGCAGGCCCGGCTTCTCTAAAGA
AGTCAGGAAAGCTGGACTTCTGCAGTGCCCTCTCCTCTCAGGGCAGCTCCCCGCGCATGGCTTTCACCCACCACCCGCTGCCTGTGCTTG
CTGGAGTCAGACCAGGGAGCCCCCGGGCCACAGCATCAGCCCTGCACTTCCCCTCCACGTCCATCATCCAGCAGTCGAGCCCGTATTTCA
CGCACCCGACCATCCGCTACCACCACCACCACGGGCAGGACTCACTGAAGGAGTTTGTGCAGTTTGTGTGCTCGGATGGCTCGGGCCAGG
CCACCGGACAGCATTCGCAACGACAGGCGCCTCCTCTGCCAACCGGTTTGTCAGCATCGGACCCCGGGACGGCAACTTTCTGAACATCCC
ACAGCAGTCTCAGTCCTGGTTCCTCTGATAAGATCGACAAAAGAAACAACAAAATGAGAAGAAGAGGTTCCTCGAAAGGGGGGAGAAGAA

>4727_4727_4_ANKRD40-NFIX_ANKRD40_chr17_48784882_ENST00000285243_NFIX_chr19_13135835_ENST00000587760_length(amino acids)=433AA_BP=1
MDEFHPFIEALLPHVRAFSYTWFNLQARKRKYFKKHEKRMSKDEERAVKDELLGEKPEIKQKWASRLLAKLRKDIRPEFREDFVLTITGK
KPPCCVLSNPDQKGKIRRIDCLRQADKVWRLDLVMVILFKGIPLESTDGERLYKSPQCSNPGLCVQPHHIGVTIKELDLYLAYFVHTPES
GQSDSSNQQGDADIKPLPNGHLSFQDCFVTSGVWNVTELVRVSQTPVATASGPNFSLADLESPSYYNINQVTLGRRSITSPPSTSTTKRP
KSIDDSEMESPVDDVFYPGTGRSPAAGSSQSSGWPNDVDAGPASLKKSGKLDFCSALSSQGSSPRMAFTHHPLPVLAGVRPGSPRATASA

--------------------------------------------------------------
>4727_4727_5_ANKRD40-NFIX_ANKRD40_chr17_48784882_ENST00000285243_NFIX_chr19_13135835_ENST00000592199_length(transcript)=1886nt_BP=404nt
TTGTCACACTGAACAGGGTCCCCCGGAGCCGGCCTTCGGGAGGCGCGGCCCGGGAGGAGGCCTGGGCCTGCGGGCCGGGAGCAGCAGGGG
CGGCCCGCGGGAGGGAGCGGAAGTCCCGGGGCGGGCGCGGGCAGCGGCGCGAGCAGGGCGGGCGAGTTCCGCGCTCCCTCCCCATGGCCG
GGAGCGGGCCGCGGCGACGGCGGCGGCGCTGACAGGCCCCGGGCGGGGCGGGGCAGGCGGGCCTGGGCGGGGGCCTGGGGCTGTGGGAAG
ATGAACGCCCTCCTAGAGCAGAAGGAGCAGCAGGAGAGGCTGCGGGAGGCCGCGGCCTTAGGGGACATTCGGGAGGTGCAGAAACTGGTG
GAGAGCGGGGTGGATGTGAACTCCCAAAATGAGGTCAACGGCTGGATGAGTTCCACCCGTTCATCGAGGCACTGCTGCCTCACGTCCGCG
CTTTCTCCTACACCTGGTTCAACCTGCAGGCGCGGAAGCGCAAGTACTTCAAGAAGCATGAAAAGCGGATGTCGAAGGACGAGGAGCGGG
CGGTGAAGGACGAGCTGCTGGGCGAGAAGCCCGAGATCAAGCAGAAGTGGGCATCCCGGCTGCTGGCCAAGCTGCGCAAGGACATCCGGC
CCGAGTTCCGCGAGGACTTCGTGCTGACCATCACGGGCAAGAAGCCCCCCTGCTGCGTGCTCTCCAACCCCGACCAGAAGGGCAAGATCC
GGCGGATTGACTGCCTGCGCCAGGCTGACAAGGTGTGGCGGCTGGACCTGGTCATGGTGATTTTGTTTAAGGGGATCCCCCTGGAAAGTA
CTGATGGGGAGCGGCTCTACAAGTCGCCTCAGTGCTCGAACCCCGGCCTGTGCGTCCAGCCACATCACATTGGAGTCACAATCAAAGAAC
TGGATCTTTATCTGGCTTACTTTGTCCACACTCCGGAATCCGGACAATCAGATAGTTCAAACCAGCAAGGAGATGCGGACATCAAACCAC
TGCCCAACGGGCACTTAAGTTTCCAGGACTGTTTTGTGACTTCCGGGGTCTGGAATGTGACGGAGCTGGTGAGAGTATCACAGACTCCTG
TTGCAACAGCATCAGGGCCCAACTTCTCCCTGGCGGACCTGGAGAGTCCCAGCTACTACAACATCAACCAGGTGACCCTGGGGCGGCGGT
CCATCACCTCCCCTCCTTCCACCAGCACCACCAAGCGCCCCAAGTCCATCGATGACAGTGAGATGGAGAGCCCTGTTGATGACGTGTTCT
ATCCCGGGACAGGCCGTTCCCCAGCAGCTGGCAGCAGCCAGTCCAGCGGGTGGCCCAACGATGTGGATGCAGGCCCGGCTTCTCTAAAGA
AGTCAGGAAAGCTGGACTTCTGCAGTGCCCTCTCCTCTCAGGGCAGCTCCCCGCGCATGGCTTTCACCCACCACCCGCTGCCTGTGCTTG
CTGGAGTCAGACCAGGGAGCCCCCGGGCCACAGCATCAGCCCTGCACTTCCCCTCCACGTCCATCATCCAGCAGTCGAGCCCGTATTTCA
CGCACCCGACCATCCGCTACCACCACCACCACGGGCAGGACTCACTGAAGGAGTTTGTGCAGTTTGTGTGCTCGGATGGCTCGGGCCAGG
CCACCGGACAGCCCAACGGTAGCGGCCAGGGCAAAGTCCCGGGGTCATTTTTGCTACCGCCGCCGCCTCCAGTGGCCAGACCTGTGCCCC
TTCCTATGCCTGATTCCAAATCCACCAGCACTGCCCCAGACGGCGCCGCCTTGACTCCTCCATCACCTTCATTCGCAACGACAGGCGCCT

>4727_4727_5_ANKRD40-NFIX_ANKRD40_chr17_48784882_ENST00000285243_NFIX_chr19_13135835_ENST00000592199_length(amino acids)=495AA_BP=1
MDEFHPFIEALLPHVRAFSYTWFNLQARKRKYFKKHEKRMSKDEERAVKDELLGEKPEIKQKWASRLLAKLRKDIRPEFREDFVLTITGK
KPPCCVLSNPDQKGKIRRIDCLRQADKVWRLDLVMVILFKGIPLESTDGERLYKSPQCSNPGLCVQPHHIGVTIKELDLYLAYFVHTPES
GQSDSSNQQGDADIKPLPNGHLSFQDCFVTSGVWNVTELVRVSQTPVATASGPNFSLADLESPSYYNINQVTLGRRSITSPPSTSTTKRP
KSIDDSEMESPVDDVFYPGTGRSPAAGSSQSSGWPNDVDAGPASLKKSGKLDFCSALSSQGSSPRMAFTHHPLPVLAGVRPGSPRATASA
LHFPSTSIIQQSSPYFTHPTIRYHHHHGQDSLKEFVQFVCSDGSGQATGQPNGSGQGKVPGSFLLPPPPPVARPVPLPMPDSKSTSTAPD

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for ANKRD40-NFIX


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for ANKRD40-NFIX


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for ANKRD40-NFIX


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneC3553660Malan overgrowth syndrome5GENOMICS_ENGLAND;ORPHANET;UNIPROT
TgeneC0265211Marshall-Smith syndrome2CTD_human;GENOMICS_ENGLAND;ORPHANET
TgeneC0005586Bipolar Disorder1PSYGENET