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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:NEMF-LINC01588 (FusionGDB2 ID:HG9147TG283551)

Fusion Gene Summary for NEMF-LINC01588

check button Fusion gene summary
Fusion gene informationFusion gene name: NEMF-LINC01588
Fusion gene ID: hg9147tg283551
HgeneTgene
Gene symbol

NEMF

LINC01588

Gene ID

9147

283551

Gene namenuclear export mediator factorlong intergenic non-protein coding RNA 1588
SynonymsNY-CO-1|SDCCAG1C14orf182
Cytomap('NEMF','NEMF')('C14orf182','LINC01588')

14q21.3

14q21.3

Type of geneprotein-codingncRNA
Descriptionnuclear export mediator factor NEMFantigen NY-CO-1serologically defined colon cancer antigen 1-
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000298310, ENST00000382135, 
ENST00000545773, ENST00000546046, 
ENST00000556925, ENST00000556672, 
Fusion gene scores* DoF score19 X 28 X 8=42563 X 3 X 4=36
# samples 264
** MAII scorelog2(26/4256*10)=-4.03291462247274
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(4/36*10)=0.15200309344505
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: NEMF [Title/Abstract] AND LINC01588 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointNEMF(50262509)-C14orf182(50459591), # samples:2
NEMF(50307436)-C14orf182(50459591), # samples:2
NEMF(50307435)-LINC01588(50459590), # samples:1
NEMF(50312857)-LINC01588(50459590), # samples:1
Anticipated loss of major functional domain due to fusion event.NEMF-C14orf182 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across NEMF (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across LINC01588 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-C8-A12P-01ANEMFchr14

50262509

-C14orf182chr14

50459591

-
ChimerDB4LUSCTCGA-37-3783-01ANEMFchr14

50307436

-C14orf182chr14

50459591

-
ChimerDB4LUSCTCGA-37-3783NEMFchr14

50307435

-C14orf182chr14

50459591

-
ChimerDB4LUSCTCGA-37-3783NEMFchr14

50307436

-C14orf182chr14

50459591

-
ChimerDB4LUSCTCGA-37-3783NEMFchr14

50312858

-C14orf182chr14

50459591

-
ChimerDB4LUSCTCGA-37-3783-01ANEMFchr14

50307435

-LINC01588chr14

50459590

-
ChimerDB4LUSCTCGA-37-3783-01ANEMFchr14

50312857

-LINC01588chr14

50459590

-


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Fusion Gene ORF analysis for NEMF-LINC01588

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000298310ENST00000529902NEMFchr14

50262509

-C14orf182chr14

50459591

-
5CDS-5UTRENST00000298310ENST00000529902NEMFchr14

50307435

-C14orf182chr14

50459591

-
5CDS-5UTRENST00000298310ENST00000529902NEMFchr14

50307436

-C14orf182chr14

50459591

-
5CDS-5UTRENST00000298310ENST00000529902NEMFchr14

50312858

-C14orf182chr14

50459591

-
5CDS-5UTRENST00000382135ENST00000529902NEMFchr14

50262509

-C14orf182chr14

50459591

-
5CDS-5UTRENST00000545773ENST00000529902NEMFchr14

50262509

-C14orf182chr14

50459591

-
5CDS-5UTRENST00000545773ENST00000529902NEMFchr14

50307435

-C14orf182chr14

50459591

-
5CDS-5UTRENST00000545773ENST00000529902NEMFchr14

50307436

-C14orf182chr14

50459591

-
5CDS-5UTRENST00000546046ENST00000529902NEMFchr14

50262509

-C14orf182chr14

50459591

-
5CDS-5UTRENST00000546046ENST00000529902NEMFchr14

50307435

-C14orf182chr14

50459591

-
5CDS-5UTRENST00000546046ENST00000529902NEMFchr14

50307436

-C14orf182chr14

50459591

-
5CDS-5UTRENST00000546046ENST00000529902NEMFchr14

50312858

-C14orf182chr14

50459591

-
5UTR-3CDSENST00000556925ENST00000399206NEMFchr14

50262509

-C14orf182chr14

50459591

-
5UTR-5UTRENST00000556925ENST00000529902NEMFchr14

50262509

-C14orf182chr14

50459591

-
Frame-shiftENST00000298310ENST00000399206NEMFchr14

50307435

-C14orf182chr14

50459591

-
Frame-shiftENST00000298310ENST00000399206NEMFchr14

50307436

-C14orf182chr14

50459591

-
Frame-shiftENST00000545773ENST00000399206NEMFchr14

50307435

-C14orf182chr14

50459591

-
Frame-shiftENST00000545773ENST00000399206NEMFchr14

50307436

-C14orf182chr14

50459591

-
Frame-shiftENST00000546046ENST00000399206NEMFchr14

50307435

-C14orf182chr14

50459591

-
Frame-shiftENST00000546046ENST00000399206NEMFchr14

50307436

-C14orf182chr14

50459591

-
In-frameENST00000298310ENST00000399206NEMFchr14

50262509

-C14orf182chr14

50459591

-
In-frameENST00000298310ENST00000399206NEMFchr14

50312858

-C14orf182chr14

50459591

-
In-frameENST00000382135ENST00000399206NEMFchr14

50262509

-C14orf182chr14

50459591

-
In-frameENST00000545773ENST00000399206NEMFchr14

50262509

-C14orf182chr14

50459591

-
In-frameENST00000546046ENST00000399206NEMFchr14

50262509

-C14orf182chr14

50459591

-
In-frameENST00000546046ENST00000399206NEMFchr14

50312858

-C14orf182chr14

50459591

-
intron-3CDSENST00000382135ENST00000399206NEMFchr14

50307435

-C14orf182chr14

50459591

-
intron-3CDSENST00000382135ENST00000399206NEMFchr14

50307436

-C14orf182chr14

50459591

-
intron-3CDSENST00000382135ENST00000399206NEMFchr14

50312858

-C14orf182chr14

50459591

-
intron-3CDSENST00000545773ENST00000399206NEMFchr14

50312858

-C14orf182chr14

50459591

-
intron-3CDSENST00000556672ENST00000399206NEMFchr14

50262509

-C14orf182chr14

50459591

-
intron-3CDSENST00000556672ENST00000399206NEMFchr14

50307435

-C14orf182chr14

50459591

-
intron-3CDSENST00000556672ENST00000399206NEMFchr14

50307436

-C14orf182chr14

50459591

-
intron-3CDSENST00000556672ENST00000399206NEMFchr14

50312858

-C14orf182chr14

50459591

-
intron-3CDSENST00000556925ENST00000399206NEMFchr14

50307435

-C14orf182chr14

50459591

-
intron-3CDSENST00000556925ENST00000399206NEMFchr14

50307436

-C14orf182chr14

50459591

-
intron-3CDSENST00000556925ENST00000399206NEMFchr14

50312858

-C14orf182chr14

50459591

-
intron-5UTRENST00000382135ENST00000529902NEMFchr14

50307435

-C14orf182chr14

50459591

-
intron-5UTRENST00000382135ENST00000529902NEMFchr14

50307436

-C14orf182chr14

50459591

-
intron-5UTRENST00000382135ENST00000529902NEMFchr14

50312858

-C14orf182chr14

50459591

-
intron-5UTRENST00000545773ENST00000529902NEMFchr14

50312858

-C14orf182chr14

50459591

-
intron-5UTRENST00000556672ENST00000529902NEMFchr14

50262509

-C14orf182chr14

50459591

-
intron-5UTRENST00000556672ENST00000529902NEMFchr14

50307435

-C14orf182chr14

50459591

-
intron-5UTRENST00000556672ENST00000529902NEMFchr14

50307436

-C14orf182chr14

50459591

-
intron-5UTRENST00000556672ENST00000529902NEMFchr14

50312858

-C14orf182chr14

50459591

-
intron-5UTRENST00000556925ENST00000529902NEMFchr14

50307435

-C14orf182chr14

50459591

-
intron-5UTRENST00000556925ENST00000529902NEMFchr14

50307436

-C14orf182chr14

50459591

-
intron-5UTRENST00000556925ENST00000529902NEMFchr14

50312858

-C14orf182chr14

50459591

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000298310NEMFchr1450262509-ENST00000399206C14orf182chr1450459591-382830694503233927
ENST00000382135NEMFchr1450262509-ENST00000399206C14orf182chr1450459591-978219948526140
ENST00000545773NEMFchr1450262509-ENST00000399206C14orf182chr1450459591-33202561682725885
ENST00000546046NEMFchr1450262509-ENST00000399206C14orf182chr1450459591-33422583272747906
ENST00000298310NEMFchr1450312858-ENST00000399206C14orf182chr1450459591-1566807450971173
ENST00000546046NEMFchr1450312858-ENST00000399206C14orf182chr1450459591-114338427548173

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000298310ENST00000399206NEMFchr1450262509-C14orf182chr1450459591-0.0015246140.9984754
ENST00000382135ENST00000399206NEMFchr1450262509-C14orf182chr1450459591-0.0572394240.9427605
ENST00000545773ENST00000399206NEMFchr1450262509-C14orf182chr1450459591-0.0018374740.99816257
ENST00000546046ENST00000399206NEMFchr1450262509-C14orf182chr1450459591-0.001901950.9980981
ENST00000298310ENST00000399206NEMFchr1450312858-C14orf182chr1450459591-0.0074416570.99255836
ENST00000546046ENST00000399206NEMFchr1450312858-C14orf182chr1450459591-0.0061178620.9938822

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Fusion Genomic Features for NEMF-LINC01588


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

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Fusion Protein Features for NEMF-LINC01588


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/:50262509/:50459591)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneNEMFchr14:50262509chr14:50459591ENST00000298310-2633296_3598731077.0Coiled coilOntology_term=ECO:0000255
HgeneNEMFchr14:50262509chr14:50459591ENST00000298310-2633483_5148731077.0Coiled coilOntology_term=ECO:0000255
HgeneNEMFchr14:50262509chr14:50459591ENST00000545773-2532296_3598311035.0Coiled coilOntology_term=ECO:0000255
HgeneNEMFchr14:50262509chr14:50459591ENST00000545773-2532483_5148311035.0Coiled coilOntology_term=ECO:0000255
HgeneNEMFchr14:50262509chr14:50459591ENST00000546046-2532296_3598521056.0Coiled coilOntology_term=ECO:0000255
HgeneNEMFchr14:50262509chr14:50459591ENST00000546046-2532483_5148521056.0Coiled coilOntology_term=ECO:0000255

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneNEMFchr14:50262509chr14:50459591ENST00000298310-2633869_8948731077.0Coiled coilOntology_term=ECO:0000255
HgeneNEMFchr14:50262509chr14:50459591ENST00000382135-29296_35973277.0Coiled coilOntology_term=ECO:0000255
HgeneNEMFchr14:50262509chr14:50459591ENST00000382135-29483_51473277.0Coiled coilOntology_term=ECO:0000255
HgeneNEMFchr14:50262509chr14:50459591ENST00000382135-29869_89473277.0Coiled coilOntology_term=ECO:0000255
HgeneNEMFchr14:50262509chr14:50459591ENST00000545773-2532869_8948311035.0Coiled coilOntology_term=ECO:0000255
HgeneNEMFchr14:50262509chr14:50459591ENST00000546046-2532869_8948521056.0Coiled coilOntology_term=ECO:0000255
HgeneNEMFchr14:50312858chr14:50459591ENST00000298310-433296_3591191077.0Coiled coilOntology_term=ECO:0000255
HgeneNEMFchr14:50312858chr14:50459591ENST00000298310-433483_5141191077.0Coiled coilOntology_term=ECO:0000255
HgeneNEMFchr14:50312858chr14:50459591ENST00000298310-433869_8941191077.0Coiled coilOntology_term=ECO:0000255
HgeneNEMFchr14:50312858chr14:50459591ENST00000382135-19296_3590277.0Coiled coilOntology_term=ECO:0000255
HgeneNEMFchr14:50312858chr14:50459591ENST00000382135-19483_5140277.0Coiled coilOntology_term=ECO:0000255
HgeneNEMFchr14:50312858chr14:50459591ENST00000382135-19869_8940277.0Coiled coilOntology_term=ECO:0000255
HgeneNEMFchr14:50312858chr14:50459591ENST00000545773-132296_35901035.0Coiled coilOntology_term=ECO:0000255
HgeneNEMFchr14:50312858chr14:50459591ENST00000545773-132483_51401035.0Coiled coilOntology_term=ECO:0000255
HgeneNEMFchr14:50312858chr14:50459591ENST00000545773-132869_89401035.0Coiled coilOntology_term=ECO:0000255
HgeneNEMFchr14:50312858chr14:50459591ENST00000546046-432296_3591191056.0Coiled coilOntology_term=ECO:0000255
HgeneNEMFchr14:50312858chr14:50459591ENST00000546046-432483_5141191056.0Coiled coilOntology_term=ECO:0000255
HgeneNEMFchr14:50312858chr14:50459591ENST00000546046-432869_8941191056.0Coiled coilOntology_term=ECO:0000255


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Fusion Gene Sequence for NEMF-LINC01588


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>58586_58586_1_NEMF-C14orf182_NEMF_chr14_50262509_ENST00000298310_C14orf182_chr14_50459591_ENST00000399206_length(transcript)=3828nt_BP=3069nt
ATTTCAAAATCTTATGTCAAAGTAAGCGCGCAGAAAGGGGTCCTTGCTCTTCTACACTGAGCCCTACGGCCCCCCTGTGGGGAAATACTC
CTGATAATCATCTCGAAAATTGTTTCGACCAGCAGGGGTCACTATGAAGGCTGACTTGAGCCCAAGACACAATGGGGCACGGTAACCAGA
CTGGTCCGTAAGGGTTCCAGGAAGGAATGCAGTTTCAAGAGAACAGTTTGAATCTTTATTCGAATTTGAATTTTGGTACAATGAAGAGAG
TCAGCTGCAACTTGACAATCGAAATCTTCAGAAAAGCGACACAAATACGTTCGCCTCGAGGAATATTGGGTCTTCTGCGCGGCCGTAGAG
CTCCGCCAAGTGCGCCTGCGCGGAGGAGAAGTGGCGTCGAGTCCGGCCGGGCAGTAGAGGAACTTGCGGTAGTGACCCTCGGGCCTCGCC
ATGAAGAGCCGCTTTAGCACCATTGACCTCCGCGCCGTACTCGCGGAGCTGAATGCTAGCTTGCTAGGAATGAGAGTAAACAATGTTTAT
GATGTGGATAATAAGACATACCTTATTCGTCTTCAAAAACCGGACTTTAAAGCTACACTTTTACTTGAATCTGGCATACGAATTCATACA
ACAGAATTTGAGTGGCCTAAGAATATGATGCCGTCTAGTTTTGCCATGAAGTGCCGAAAACATTTGAAGAGTCGGAGATTAGTCAGTGCA
AAACAGCTTGGTGTGGATAGAATTGTAGATTTTCAATTTGGAAGTGATGAAGCTGCTTACCATTTAATCATTGAGCTCTATGATAGGGGG
AACATTGTTCTTACAGATTATGAGTACGTAATTTTAAATATTCTAAGGTTTCGAACTGATGAGGCAGATGATGTTAAATTTGCTGTTCGT
GAACGCTATCCACTTGATCATGCTAGAGCTGCTGAACCTTTGCTTACTTTGGAAAGGTTGACTGAAATAGTAGCCAGCGCACCTAAGGGT
GAACTACTGAAGAGGGTGCTTAACCCATTACTTCCCTATGGACCAGCTCTCATTGAACACTGTCTTTTAGAAAATGGATTCTCGGGTAAT
GTCAAAGTGGATGAAAAACTTGAAACTAAAGATATTGAAAAAGTACTTGTTTCTCTGCAGAAAGCAGAAGACTATATGAAAACAACATCC
AACTTCAGTGGGAAGGGATATATCATTCAGAAAAGAGAAATAAAACCAAGCTTGGAAGCAGATAAACCAGTTGAAGACATACTGACGTAT
GAGGAATTTCATCCTTTCTTGTTTTCTCAACATTCACAATGTCCATATATAGAATTTGAATCATTTGACAAGGCGGTGGATGAATTTTAT
TCCAAGATAGAAGGCCAGAAAATTGACTTAAAAGCTTTACAACAGGAAAAGCAAGCATTGAAGAAATTAGATAATGTTCGAAAGGATCAC
GAAAACAGATTGGAAGCTCTTCAGCAGGCTCAGGAAATAGACAAACTGAAAGGAGAGCTCATAGAAATGAACCTACAAATAGTTGACAGA
GCCATTCAGGTAGTTCGAAGTGCTTTAGCTAACCAGATAGATTGGACAGAAATTGGGTTAATTGTGAAAGAAGCCCAGGCTCAAGGAGAC
CCTGTTGCAAGTGCAATCAAAGAATTAAAACTACAAACAAACCATGTTACAATGCTGCTAAGAAATCCATACTTGTTATCAGAGGAGGAA
GATGATGATGTTGATGGTGACGTCAATGTTGAGAAAAATGAAACTGAACCACCAAAAGGAAAAAAGAAAAAACAAAAGAATAAACAGCTG
CAGAAGCCTCAGAAAAATAAGCCCTTACTTGTAGATGTTGATCTCAGCTTGTCAGCATATGCCAATGCCAAAAAGTATTATGATCACAAG
AGATATGCTGCTAAGAAAACACAAAAGACTGTTGAAGCTGCTGAGAAGGCATTCAAGTCAGCAGAAAAGAAAACAAAGCAAACATTAAAA
GAAGTTCAGACTGTTACCTCTATTCAAAAAGCAAGAAAAGTATATTGGTTTGAGAAATTTCTGTGGTTCATTAGCTCAGAGAACTATCTA
ATTATAGGTGGACGAGATCAGCAACAGAATGAAATAATTGTGAAAAGATACTTGACACCAGGAGACATTTATGTACATGCTGATCTTCAT
GGAGCTACTAGCTGTGTAATTAAGAATCCAACAGGAGAACCCATCCCCCCACGGACCTTGACTGAAGCTGGCACAATGGCACTTTGCTAC
AGTGCTGCTTGGGATGCACGAGTTATCACTAGTGCTTGGTGGGTGTACCATCATCAGGTATCTAAAACAGCACCAACTGGAGAATATTTG
ACAACAGGAAGCTTCATGATAAGAGGAAAAAAGAATTTTCTTCCTCCCTCATATCTAATGATGGGGTTTAGCTTCCTTTTTAAGGTAGAT
GAGTCTTGTGTTTGGAGACATCAGGGTGAACGAAAAGTCAGAGTACAGGATGAAGACATGGAGACACTGGCAAGTTGTACAAGTGAACTC
ATATCAGAAGAAATGGAACAATTAGATGGAGGTGACACGAGCAGTGATGAGGATAAAGAAGAACATGAAACTCCTGTGGAAGTAGAACTC
ATGACTCAGGTTGACCAAGAGGATATCACTCTTCAGAGTGGCAGAGATGAACTAAATGAGGAGCTCATTCAGGAAGAAAGCTCTGAAGAC
GAAGGAGAATATGAAGAGGTTAGAAAAGATCAGGATTCTGTTGGTGAAATGAAGGATGAAGGGGAAGAGACATTAAATTATCCTGATACT
ACCATTGACTTGTCTCACCTTCAACCCCAAAGGTCCATCCAGAAATTGGCTTCAAAAGAGGAATCTTCTAATTCTAGTGACAGTAAATCA
CAGAGCCGGAGACATTTGTCAGCCAAGGAAAGAAGGGAAATGAAAAAGAAAAAACTTCCAAGTGACTCAGGAGATTTAGAAGCGTTAGAG
GGAAAGGATAAAGAAAAAGAAAGTACTGTACACATTGAAACTCATCAGAACACAAGCAAAAATGTTGCGGCTGTGCAGCCAATGAAACGA
GGACAAAAGGAGAAAGAATTGTGCCATGAAAAATGGAAAACTCCTGAGAAGCTGTTCCAGCGTCAGGAGAGCAGCAGACAAGCTGGACTG
GGGAAGATTCTTCCTGCAAGACCTGCAGAGTGTATGACACATAACCAGCACCCAAGAAATGTCTACCGAGGAATTAATGAATGAGGAAAT
ACCTCTGTACACTCACCAGACACTGGCTGCTGGTTGTCACGGTGCTAAGAGCTGTGGGAAACATGAAGAGCAATGAGACCAGGTCCCTGC
TCTGAGGAGACGTGTGCCAGCGAAGTTTCTCTCCCACGTGAGTGTGCTACAAGAAAATCTGAACCCGAGAATCTGATTCAGTAGGTCTGC
ACTTTCTCCACTTTGCCAGATAATTCTGATTGAGACCGTCAAGGCTGTGACTAGTGGGGAGGCAGTAGAGTATTTTCTGTGCTAGACTGA
GGCAGCCCTGAAGCACTGCGCAAGCACATGGAAAAGAGAAACGAGATTGGGCCGGGCACGGTGGCTCATGCCTGGAATCTTTGGGAGGCC
ACGGATCACTTGAGGACAGGGGTTTGAGACCAGCTTGGCCAACATGGTGAAACCTTGTCCCTACTAAAAATACAAAAATTAGCAGGGAGT
GGTGGTGCACACCTGTAATCCCAGCTACTCTGGAGGCTGAGGCAAAAGAATCGCTTGAACCCGGGAGGTGGAGGTTGCAGTGAGCTGAGA
TTGGACCACTGCCCTCCAGCCTGGGTGATAGAGTGAGACTCCATCTCT

>58586_58586_1_NEMF-C14orf182_NEMF_chr14_50262509_ENST00000298310_C14orf182_chr14_50459591_ENST00000399206_length(amino acids)=927AA_BP=873
MKSRFSTIDLRAVLAELNASLLGMRVNNVYDVDNKTYLIRLQKPDFKATLLLESGIRIHTTEFEWPKNMMPSSFAMKCRKHLKSRRLVSA
KQLGVDRIVDFQFGSDEAAYHLIIELYDRGNIVLTDYEYVILNILRFRTDEADDVKFAVRERYPLDHARAAEPLLTLERLTEIVASAPKG
ELLKRVLNPLLPYGPALIEHCLLENGFSGNVKVDEKLETKDIEKVLVSLQKAEDYMKTTSNFSGKGYIIQKREIKPSLEADKPVEDILTY
EEFHPFLFSQHSQCPYIEFESFDKAVDEFYSKIEGQKIDLKALQQEKQALKKLDNVRKDHENRLEALQQAQEIDKLKGELIEMNLQIVDR
AIQVVRSALANQIDWTEIGLIVKEAQAQGDPVASAIKELKLQTNHVTMLLRNPYLLSEEEDDDVDGDVNVEKNETEPPKGKKKKQKNKQL
QKPQKNKPLLVDVDLSLSAYANAKKYYDHKRYAAKKTQKTVEAAEKAFKSAEKKTKQTLKEVQTVTSIQKARKVYWFEKFLWFISSENYL
IIGGRDQQQNEIIVKRYLTPGDIYVHADLHGATSCVIKNPTGEPIPPRTLTEAGTMALCYSAAWDARVITSAWWVYHHQVSKTAPTGEYL
TTGSFMIRGKKNFLPPSYLMMGFSFLFKVDESCVWRHQGERKVRVQDEDMETLASCTSELISEEMEQLDGGDTSSDEDKEEHETPVEVEL
MTQVDQEDITLQSGRDELNEELIQEESSEDEGEYEEVRKDQDSVGEMKDEGEETLNYPDTTIDLSHLQPQRSIQKLASKEESSNSSDSKS
QSRRHLSAKERREMKKKKLPSDSGDLEALEGKDKEKESTVHIETHQNTSKNVAAVQPMKRGQKEKELCHEKWKTPEKLFQRQESSRQAGL
GKILPARPAECMTHNQHPRNVYRGINE

--------------------------------------------------------------
>58586_58586_2_NEMF-C14orf182_NEMF_chr14_50262509_ENST00000382135_C14orf182_chr14_50459591_ENST00000399206_length(transcript)=978nt_BP=219nt
ATGCCTAAGACCTGCCAATGCTATGTTGGTACAAAGACTACAAATCCCAGTGCCTGGCCATCAAGGGAAATGAAAAAGAAAAAACTTCCA
AGTGACTCAGGAGATTTAGAAGCGTTAGAGGGAAAGGATAAAGAAAAAGAAAGTACTGTACACATTGAAACTCATCAGAACACAAGCAAA
AATGTTGCGGCTGTGCAGCCAATGAAACGAGGACAAAAGGAGAAAGAATTGTGCCATGAAAAATGGAAAACTCCTGAGAAGCTGTTCCAG
CGTCAGGAGAGCAGCAGACAAGCTGGACTGGGGAAGATTCTTCCTGCAAGACCTGCAGAGTGTATGACACATAACCAGCACCCAAGAAAT
GTCTACCGAGGAATTAATGAATGAGGAAATACCTCTGTACACTCACCAGACACTGGCTGCTGGTTGTCACGGTGCTAAGAGCTGTGGGAA
ACATGAAGAGCAATGAGACCAGGTCCCTGCTCTGAGGAGACGTGTGCCAGCGAAGTTTCTCTCCCACGTGAGTGTGCTACAAGAAAATCT
GAACCCGAGAATCTGATTCAGTAGGTCTGCACTTTCTCCACTTTGCCAGATAATTCTGATTGAGACCGTCAAGGCTGTGACTAGTGGGGA
GGCAGTAGAGTATTTTCTGTGCTAGACTGAGGCAGCCCTGAAGCACTGCGCAAGCACATGGAAAAGAGAAACGAGATTGGGCCGGGCACG
GTGGCTCATGCCTGGAATCTTTGGGAGGCCACGGATCACTTGAGGACAGGGGTTTGAGACCAGCTTGGCCAACATGGTGAAACCTTGTCC
CTACTAAAAATACAAAAATTAGCAGGGAGTGGTGGTGCACACCTGTAATCCCAGCTACTCTGGAGGCTGAGGCAAAAGAATCGCTTGAAC
CCGGGAGGTGGAGGTTGCAGTGAGCTGAGATTGGACCACTGCCCTCCAGCCTGGGTGATAGAGTGAGACTCCATCTCT

>58586_58586_2_NEMF-C14orf182_NEMF_chr14_50262509_ENST00000382135_C14orf182_chr14_50459591_ENST00000399206_length(amino acids)=140AA_BP=
MEGSGPISAHCNLHLPGSSDSFASASRVAGITGVHHHSLLIFVFLVGTRFHHVGQAGLKPLSSSDPWPPKDSRHEPPCPAQSRFSFPCAC
AVLQGCLSLAQKILYCLPTSHSLDGLNQNYLAKWRKCRPTESDSRVQIFL

--------------------------------------------------------------
>58586_58586_3_NEMF-C14orf182_NEMF_chr14_50262509_ENST00000545773_C14orf182_chr14_50459591_ENST00000399206_length(transcript)=3320nt_BP=2561nt
GAGGAGAAGTGGCGTCGAGTCCGGCCGGGCAGTAGAGGAACTTGCGGTAGTGACCCTCGGGCCTCGCCATGAAGAGCCGCTTTAGCACCA
TTGACCTCCGCGCCGTACTCGCGGAGCTGAATGCTAGCTTGCTAGGAATGAGAGTAAACAATGTTTATGATGTGGATAATAAGACATACC
TTATTCGTCTTCAAAAACCGGACTTTAAAGCTACACTTTTACTTGAATCTGGCATACGAATTCATACAACAGAATTTGAGTGGCCTAAGA
ATATGATGCCGTCTAGTTTTGCCATGAAGGGGAACATTGTTCTTACAGATTATGAGTACGTAATTTTAAATATTCTAAGGTTTCGAACTG
ATGAGGCAGATGATGTTAAATTTGCTGTTCGTGAACGCTATCCACTTGATCATGCTAGAGCTGCTGAACCTTTGCTTACTTTGGAAAGGT
TGACTGAAATAGTAGCCAGCGCACCTAAGGGTGAACTACTGAAGAGGGTGCTTAACCCATTACTTCCCTATGGACCAGCTCTCATTGAAC
ACTGTCTTTTAGAAAATGGATTCTCGGGTAATGTCAAAGTGGATGAAAAACTTGAAACTAAAGATATTGAAAAAGTACTTGTTTCTCTGC
AGAAAGCAGAAGACTATATGAAAACAACATCCAACTTCAGTGGGAAGGGATATATCATTCAGAAAAGAGAAATAAAACCAAGCTTGGAAG
CAGATAAACCAGTTGAAGACATACTGACGTATGAGGAATTTCATCCTTTCTTGTTTTCTCAACATTCACAATGTCCATATATAGAATTTG
AATCATTTGACAAGGCGGTGGATGAATTTTATTCCAAGATAGAAGGCCAGAAAATTGACTTAAAAGCTTTACAACAGGAAAAGCAAGCAT
TGAAGAAATTAGATAATGTTCGAAAGGATCACGAAAACAGATTGGAAGCTCTTCAGCAGGCTCAGGAAATAGACAAACTGAAAGGAGAGC
TCATAGAAATGAACCTACAAATAGTTGACAGAGCCATTCAGGTAGTTCGAAGTGCTTTAGCTAACCAGATAGATTGGACAGAAATTGGGT
TAATTGTGAAAGAAGCCCAGGCTCAAGGAGACCCTGTTGCAAGTGCAATCAAAGAATTAAAACTACAAACAAACCATGTTACAATGCTGC
TAAGAAATCCATACTTGTTATCAGAGGAGGAAGATGATGATGTTGATGGTGACGTCAATGTTGAGAAAAATGAAACTGAACCACCAAAAG
GAAAAAAGAAAAAACAAAAGAATAAACAGCTGCAGAAGCCTCAGAAAAATAAGCCCTTACTTGTAGATGTTGATCTCAGCTTGTCAGCAT
ATGCCAATGCCAAAAAGTATTATGATCACAAGAGATATGCTGCTAAGAAAACACAAAAGACTGTTGAAGCTGCTGAGAAGGCATTCAAGT
CAGCAGAAAAGAAAACAAAGCAAACATTAAAAGAAGTTCAGACTGTTACCTCTATTCAAAAAGCAAGAAAAGTATATTGGTTTGAGAAAT
TTCTGTGGTTCATTAGCTCAGAGAACTATCTAATTATAGGTGGACGAGATCAGCAACAGAATGAAATAATTGTGAAAAGATACTTGACAC
CAGGAGACATTTATGTACATGCTGATCTTCATGGAGCTACTAGCTGTGTAATTAAGAATCCAACAGGAGAACCCATCCCCCCACGGACCT
TGACTGAAGCTGGCACAATGGCACTTTGCTACAGTGCTGCTTGGGATGCACGAGTTATCACTAGTGCTTGGTGGGTGTACCATCATCAGG
TATCTAAAACAGCACCAACTGGAGAATATTTGACAACAGGAAGCTTCATGATAAGAGGAAAAAAGAATTTTCTTCCTCCCTCATATCTAA
TGATGGGGTTTAGCTTCCTTTTTAAGGTAGATGAGTCTTGTGTTTGGAGACATCAGGGTGAACGAAAAGTCAGAGTACAGGATGAAGACA
TGGAGACACTGGCAAGTTGTACAAGTGAACTCATATCAGAAGAAATGGAACAATTAGATGGAGGTGACACGAGCAGTGATGAGGATAAAG
AAGAACATGAAACTCCTGTGGAAGTAGAACTCATGACTCAGGTTGACCAAGAGGATATCACTCTTCAGAGTGGCAGAGATGAACTAAATG
AGGAGCTCATTCAGGAAGAAAGCTCTGAAGACGAAGGAGAATATGAAGAGGTTAGAAAAGATCAGGATTCTGTTGGTGAAATGAAGGATG
AAGGGGAAGAGACATTAAATTATCCTGATACTACCATTGACTTGTCTCACCTTCAACCCCAAAGGTCCATCCAGAAATTGGCTTCAAAAG
AGGAATCTTCTAATTCTAGTGACAGTAAATCACAGAGCCGGAGACATTTGTCAGCCAAGGAAAGAAGGGAAATGAAAAAGAAAAAACTTC
CAAGTGACTCAGGAGATTTAGAAGCGTTAGAGGGAAAGGATAAAGAAAAAGAAAGTACTGTACACATTGAAACTCATCAGAACACAAGCA
AAAATGTTGCGGCTGTGCAGCCAATGAAACGAGGACAAAAGGAGAAAGAATTGTGCCATGAAAAATGGAAAACTCCTGAGAAGCTGTTCC
AGCGTCAGGAGAGCAGCAGACAAGCTGGACTGGGGAAGATTCTTCCTGCAAGACCTGCAGAGTGTATGACACATAACCAGCACCCAAGAA
ATGTCTACCGAGGAATTAATGAATGAGGAAATACCTCTGTACACTCACCAGACACTGGCTGCTGGTTGTCACGGTGCTAAGAGCTGTGGG
AAACATGAAGAGCAATGAGACCAGGTCCCTGCTCTGAGGAGACGTGTGCCAGCGAAGTTTCTCTCCCACGTGAGTGTGCTACAAGAAAAT
CTGAACCCGAGAATCTGATTCAGTAGGTCTGCACTTTCTCCACTTTGCCAGATAATTCTGATTGAGACCGTCAAGGCTGTGACTAGTGGG
GAGGCAGTAGAGTATTTTCTGTGCTAGACTGAGGCAGCCCTGAAGCACTGCGCAAGCACATGGAAAAGAGAAACGAGATTGGGCCGGGCA
CGGTGGCTCATGCCTGGAATCTTTGGGAGGCCACGGATCACTTGAGGACAGGGGTTTGAGACCAGCTTGGCCAACATGGTGAAACCTTGT
CCCTACTAAAAATACAAAAATTAGCAGGGAGTGGTGGTGCACACCTGTAATCCCAGCTACTCTGGAGGCTGAGGCAAAAGAATCGCTTGA
ACCCGGGAGGTGGAGGTTGCAGTGAGCTGAGATTGGACCACTGCCCTCCAGCCTGGGTGATAGAGTGAGACTCCATCTCT

>58586_58586_3_NEMF-C14orf182_NEMF_chr14_50262509_ENST00000545773_C14orf182_chr14_50459591_ENST00000399206_length(amino acids)=885AA_BP=831
MKSRFSTIDLRAVLAELNASLLGMRVNNVYDVDNKTYLIRLQKPDFKATLLLESGIRIHTTEFEWPKNMMPSSFAMKGNIVLTDYEYVIL
NILRFRTDEADDVKFAVRERYPLDHARAAEPLLTLERLTEIVASAPKGELLKRVLNPLLPYGPALIEHCLLENGFSGNVKVDEKLETKDI
EKVLVSLQKAEDYMKTTSNFSGKGYIIQKREIKPSLEADKPVEDILTYEEFHPFLFSQHSQCPYIEFESFDKAVDEFYSKIEGQKIDLKA
LQQEKQALKKLDNVRKDHENRLEALQQAQEIDKLKGELIEMNLQIVDRAIQVVRSALANQIDWTEIGLIVKEAQAQGDPVASAIKELKLQ
TNHVTMLLRNPYLLSEEEDDDVDGDVNVEKNETEPPKGKKKKQKNKQLQKPQKNKPLLVDVDLSLSAYANAKKYYDHKRYAAKKTQKTVE
AAEKAFKSAEKKTKQTLKEVQTVTSIQKARKVYWFEKFLWFISSENYLIIGGRDQQQNEIIVKRYLTPGDIYVHADLHGATSCVIKNPTG
EPIPPRTLTEAGTMALCYSAAWDARVITSAWWVYHHQVSKTAPTGEYLTTGSFMIRGKKNFLPPSYLMMGFSFLFKVDESCVWRHQGERK
VRVQDEDMETLASCTSELISEEMEQLDGGDTSSDEDKEEHETPVEVELMTQVDQEDITLQSGRDELNEELIQEESSEDEGEYEEVRKDQD
SVGEMKDEGEETLNYPDTTIDLSHLQPQRSIQKLASKEESSNSSDSKSQSRRHLSAKERREMKKKKLPSDSGDLEALEGKDKEKESTVHI
ETHQNTSKNVAAVQPMKRGQKEKELCHEKWKTPEKLFQRQESSRQAGLGKILPARPAECMTHNQHPRNVYRGINE

--------------------------------------------------------------
>58586_58586_4_NEMF-C14orf182_NEMF_chr14_50262509_ENST00000546046_C14orf182_chr14_50459591_ENST00000399206_length(transcript)=3342nt_BP=2583nt
TTGCGGTAGTGACCCTCGGGCCTCGCCATGAAGAGCCGCTTTAGCACCATTGACCTCCGCGCCGTACTCGCGGAGCTGAATGCTAGCTTG
CTAGGAATGAGAGTAAACAATGTTTATGATGTGGATAATAAGACATACCTTATTCGTCTTCAAAAACCGGACTTTAAAGCTACACTTTTA
CTTGAATCTGGCATACGAATTCATACAACAGAATTTGAGTGGCCTAAGAATATGATGCCGTCTAGTTTTGCCATGAAGTGCCGAAAACAT
TTGAAGAGTCGGAGATTAGTCAGTGCAAAACAGCTTGGTGTGGATAGAATTGTAGATTTTCAATTTGGAAGTGATGAAGCTGCTTACCAT
TTAATCATTGAGCTCTATGATAGGGGGAACATTGTTCTTACAGATTATGAGTACGTAATTTTAAATATTCTAAGGTTTCGAACTGATGAG
GCAGATGATGTTAAATTTGCTGTTCGTGAACGCTATCCACTTGATCATGCTAGAGCTGCTGAACCTTTGCTTACTTTGGAAAGGTTGACT
GAAATAGTAGCCAGCGCACCTAAGGGTGAACTACTGAAGAGGGTGCTTAACCCATTACTTCCCTATGGACCAGCTCTCATTGAACACTGT
CTTTTAGAAAATGGATTCTCGGGTAATGTCAAAGTGGATGAAAAACTTGAAACTAAAGATATTGAAAAAGTACTTGTTTCTCTGCAGAAA
GCAGAAGACTATATGAAAACAACATCCAACTTCAGTGGGAAGGGATATATCATTCAGAAAAGAGAAATAAAACCAAGCTTGGAAGCAGAT
AAACCAGTTGAAGACATACTGACGTATGAGGAATTTCATCCTTTCTTGTTTTCTCAACATTCACAATGTCCATATATAGAATTTGAATCA
TTTGACAAGGCGGTGGATGAATTTTATTCCAAGATAGAAGGCCAGAAAATTGACTTAAAAGCTTTACAACAGGAAAAGCAAGCATTGAAG
AAATTAGATAATGTTCGAAAGGATCACGAAAACAGATTGGAAGCTCTTCAGCAGGCTCAGGAAATAGACAAACTGAAAGGAGAGCTCATA
GAAATGAACCTACAAATAGTTGACAGAGCCATTCAGGTAGTTCGAAGTGCTTTAGCTAACCAGATAGATTGGACAGAAATTGGGTTAATT
GTGAAAGAAGCCCAGGCTCAAGGAGACCCTGTTGCAAGTGCAATCAAAGAATTAAAACTACAAACAAACCATGTTACAATGCTGCTAAGA
AATCCATACTTGTTATCAGAGGAGGAAGATGATGATGTTGATGGTGACGTCAATGTTGAGAAAAATGAAACTGAACCACCAAAAGGAAAA
AAGAAAAAACAAAAGAATAAACAGCTGCAGAAGCCTCAGAAAAATAAGCCCTTACTTGTAGATGTTGATCTCAGCTTGTCAGCATATGCC
AATGCCAAAAAGTATTATGATCACAAGAGATATGCTGCTAAGAAAACACAAAAGACTGTTGAAGCTGCTGAGAAGGCATTCAAGTCAGCA
GAAAAGAAAACAAAGCAAACATTAAAAGAAGTTCAGACTGTTACCTCTATTCAAAAAGCAAGAAAAGTATATTGGTTTGAGAAATTTCTG
TGGTTCATTAGCTCAGAGAACTATCTAATTATAGGTGGACGAGATCAGCAACAGAATGAAATAATTGTGAAAAGATACTTGACACCAGGA
GAACCCATCCCCCCACGGACCTTGACTGAAGCTGGCACAATGGCACTTTGCTACAGTGCTGCTTGGGATGCACGAGTTATCACTAGTGCT
TGGTGGGTGTACCATCATCAGGTATCTAAAACAGCACCAACTGGAGAATATTTGACAACAGGAAGCTTCATGATAAGAGGAAAAAAGAAT
TTTCTTCCTCCCTCATATCTAATGATGGGGTTTAGCTTCCTTTTTAAGGTAGATGAGTCTTGTGTTTGGAGACATCAGGGTGAACGAAAA
GTCAGAGTACAGGATGAAGACATGGAGACACTGGCAAGTTGTACAAGTGAACTCATATCAGAAGAAATGGAACAATTAGATGGAGGTGAC
ACGAGCAGTGATGAGGATAAAGAAGAACATGAAACTCCTGTGGAAGTAGAACTCATGACTCAGGTTGACCAAGAGGATATCACTCTTCAG
AGTGGCAGAGATGAACTAAATGAGGAGCTCATTCAGGAAGAAAGCTCTGAAGACGAAGGAGAATATGAAGAGGTTAGAAAAGATCAGGAT
TCTGTTGGTGAAATGAAGGATGAAGGGGAAGAGACATTAAATTATCCTGATACTACCATTGACTTGTCTCACCTTCAACCCCAAAGGTCC
ATCCAGAAATTGGCTTCAAAAGAGGAATCTTCTAATTCTAGTGACAGTAAATCACAGAGCCGGAGACATTTGTCAGCCAAGGAAAGAAGG
GAAATGAAAAAGAAAAAACTTCCAAGTGACTCAGGAGATTTAGAAGCGTTAGAGGGAAAGGATAAAGAAAAAGAAAGTACTGTACACATT
GAAACTCATCAGAACACAAGCAAAAATGTTGCGGCTGTGCAGCCAATGAAACGAGGACAAAAGGAGAAAGAATTGTGCCATGAAAAATGG
AAAACTCCTGAGAAGCTGTTCCAGCGTCAGGAGAGCAGCAGACAAGCTGGACTGGGGAAGATTCTTCCTGCAAGACCTGCAGAGTGTATG
ACACATAACCAGCACCCAAGAAATGTCTACCGAGGAATTAATGAATGAGGAAATACCTCTGTACACTCACCAGACACTGGCTGCTGGTTG
TCACGGTGCTAAGAGCTGTGGGAAACATGAAGAGCAATGAGACCAGGTCCCTGCTCTGAGGAGACGTGTGCCAGCGAAGTTTCTCTCCCA
CGTGAGTGTGCTACAAGAAAATCTGAACCCGAGAATCTGATTCAGTAGGTCTGCACTTTCTCCACTTTGCCAGATAATTCTGATTGAGAC
CGTCAAGGCTGTGACTAGTGGGGAGGCAGTAGAGTATTTTCTGTGCTAGACTGAGGCAGCCCTGAAGCACTGCGCAAGCACATGGAAAAG
AGAAACGAGATTGGGCCGGGCACGGTGGCTCATGCCTGGAATCTTTGGGAGGCCACGGATCACTTGAGGACAGGGGTTTGAGACCAGCTT
GGCCAACATGGTGAAACCTTGTCCCTACTAAAAATACAAAAATTAGCAGGGAGTGGTGGTGCACACCTGTAATCCCAGCTACTCTGGAGG
CTGAGGCAAAAGAATCGCTTGAACCCGGGAGGTGGAGGTTGCAGTGAGCTGAGATTGGACCACTGCCCTCCAGCCTGGGTGATAGAGTGA
GACTCCATCTCT

>58586_58586_4_NEMF-C14orf182_NEMF_chr14_50262509_ENST00000546046_C14orf182_chr14_50459591_ENST00000399206_length(amino acids)=906AA_BP=852
MKSRFSTIDLRAVLAELNASLLGMRVNNVYDVDNKTYLIRLQKPDFKATLLLESGIRIHTTEFEWPKNMMPSSFAMKCRKHLKSRRLVSA
KQLGVDRIVDFQFGSDEAAYHLIIELYDRGNIVLTDYEYVILNILRFRTDEADDVKFAVRERYPLDHARAAEPLLTLERLTEIVASAPKG
ELLKRVLNPLLPYGPALIEHCLLENGFSGNVKVDEKLETKDIEKVLVSLQKAEDYMKTTSNFSGKGYIIQKREIKPSLEADKPVEDILTY
EEFHPFLFSQHSQCPYIEFESFDKAVDEFYSKIEGQKIDLKALQQEKQALKKLDNVRKDHENRLEALQQAQEIDKLKGELIEMNLQIVDR
AIQVVRSALANQIDWTEIGLIVKEAQAQGDPVASAIKELKLQTNHVTMLLRNPYLLSEEEDDDVDGDVNVEKNETEPPKGKKKKQKNKQL
QKPQKNKPLLVDVDLSLSAYANAKKYYDHKRYAAKKTQKTVEAAEKAFKSAEKKTKQTLKEVQTVTSIQKARKVYWFEKFLWFISSENYL
IIGGRDQQQNEIIVKRYLTPGEPIPPRTLTEAGTMALCYSAAWDARVITSAWWVYHHQVSKTAPTGEYLTTGSFMIRGKKNFLPPSYLMM
GFSFLFKVDESCVWRHQGERKVRVQDEDMETLASCTSELISEEMEQLDGGDTSSDEDKEEHETPVEVELMTQVDQEDITLQSGRDELNEE
LIQEESSEDEGEYEEVRKDQDSVGEMKDEGEETLNYPDTTIDLSHLQPQRSIQKLASKEESSNSSDSKSQSRRHLSAKERREMKKKKLPS
DSGDLEALEGKDKEKESTVHIETHQNTSKNVAAVQPMKRGQKEKELCHEKWKTPEKLFQRQESSRQAGLGKILPARPAECMTHNQHPRNV
YRGINE

--------------------------------------------------------------
>58586_58586_5_NEMF-C14orf182_NEMF_chr14_50312858_ENST00000298310_C14orf182_chr14_50459591_ENST00000399206_length(transcript)=1566nt_BP=807nt
ATTTCAAAATCTTATGTCAAAGTAAGCGCGCAGAAAGGGGTCCTTGCTCTTCTACACTGAGCCCTACGGCCCCCCTGTGGGGAAATACTC
CTGATAATCATCTCGAAAATTGTTTCGACCAGCAGGGGTCACTATGAAGGCTGACTTGAGCCCAAGACACAATGGGGCACGGTAACCAGA
CTGGTCCGTAAGGGTTCCAGGAAGGAATGCAGTTTCAAGAGAACAGTTTGAATCTTTATTCGAATTTGAATTTTGGTACAATGAAGAGAG
TCAGCTGCAACTTGACAATCGAAATCTTCAGAAAAGCGACACAAATACGTTCGCCTCGAGGAATATTGGGTCTTCTGCGCGGCCGTAGAG
CTCCGCCAAGTGCGCCTGCGCGGAGGAGAAGTGGCGTCGAGTCCGGCCGGGCAGTAGAGGAACTTGCGGTAGTGACCCTCGGGCCTCGCC
ATGAAGAGCCGCTTTAGCACCATTGACCTCCGCGCCGTACTCGCGGAGCTGAATGCTAGCTTGCTAGGAATGAGAGTAAACAATGTTTAT
GATGTGGATAATAAGACATACCTTATTCGTCTTCAAAAACCGGACTTTAAAGCTACACTTTTACTTGAATCTGGCATACGAATTCATACA
ACAGAATTTGAGTGGCCTAAGAATATGATGCCGTCTAGTTTTGCCATGAAGTGCCGAAAACATTTGAAGAGTCGGAGATTAGTCAGTGCA
AAACAGCTTGGTGTGGATAGAATTGTAGATTTTCAATTTGGAAGTGATGAAGCTGCTTACCATTTAATCATTGAGCTCTATGATAGGGAG
AAAGAATTGTGCCATGAAAAATGGAAAACTCCTGAGAAGCTGTTCCAGCGTCAGGAGAGCAGCAGACAAGCTGGACTGGGGAAGATTCTT
CCTGCAAGACCTGCAGAGTGTATGACACATAACCAGCACCCAAGAAATGTCTACCGAGGAATTAATGAATGAGGAAATACCTCTGTACAC
TCACCAGACACTGGCTGCTGGTTGTCACGGTGCTAAGAGCTGTGGGAAACATGAAGAGCAATGAGACCAGGTCCCTGCTCTGAGGAGACG
TGTGCCAGCGAAGTTTCTCTCCCACGTGAGTGTGCTACAAGAAAATCTGAACCCGAGAATCTGATTCAGTAGGTCTGCACTTTCTCCACT
TTGCCAGATAATTCTGATTGAGACCGTCAAGGCTGTGACTAGTGGGGAGGCAGTAGAGTATTTTCTGTGCTAGACTGAGGCAGCCCTGAA
GCACTGCGCAAGCACATGGAAAAGAGAAACGAGATTGGGCCGGGCACGGTGGCTCATGCCTGGAATCTTTGGGAGGCCACGGATCACTTG
AGGACAGGGGTTTGAGACCAGCTTGGCCAACATGGTGAAACCTTGTCCCTACTAAAAATACAAAAATTAGCAGGGAGTGGTGGTGCACAC
CTGTAATCCCAGCTACTCTGGAGGCTGAGGCAAAAGAATCGCTTGAACCCGGGAGGTGGAGGTTGCAGTGAGCTGAGATTGGACCACTGC
CCTCCAGCCTGGGTGATAGAGTGAGACTCCATCTCT

>58586_58586_5_NEMF-C14orf182_NEMF_chr14_50312858_ENST00000298310_C14orf182_chr14_50459591_ENST00000399206_length(amino acids)=173AA_BP=119
MKSRFSTIDLRAVLAELNASLLGMRVNNVYDVDNKTYLIRLQKPDFKATLLLESGIRIHTTEFEWPKNMMPSSFAMKCRKHLKSRRLVSA
KQLGVDRIVDFQFGSDEAAYHLIIELYDREKELCHEKWKTPEKLFQRQESSRQAGLGKILPARPAECMTHNQHPRNVYRGINE

--------------------------------------------------------------
>58586_58586_6_NEMF-C14orf182_NEMF_chr14_50312858_ENST00000546046_C14orf182_chr14_50459591_ENST00000399206_length(transcript)=1143nt_BP=384nt
TTGCGGTAGTGACCCTCGGGCCTCGCCATGAAGAGCCGCTTTAGCACCATTGACCTCCGCGCCGTACTCGCGGAGCTGAATGCTAGCTTG
CTAGGAATGAGAGTAAACAATGTTTATGATGTGGATAATAAGACATACCTTATTCGTCTTCAAAAACCGGACTTTAAAGCTACACTTTTA
CTTGAATCTGGCATACGAATTCATACAACAGAATTTGAGTGGCCTAAGAATATGATGCCGTCTAGTTTTGCCATGAAGTGCCGAAAACAT
TTGAAGAGTCGGAGATTAGTCAGTGCAAAACAGCTTGGTGTGGATAGAATTGTAGATTTTCAATTTGGAAGTGATGAAGCTGCTTACCAT
TTAATCATTGAGCTCTATGATAGGGAGAAAGAATTGTGCCATGAAAAATGGAAAACTCCTGAGAAGCTGTTCCAGCGTCAGGAGAGCAGC
AGACAAGCTGGACTGGGGAAGATTCTTCCTGCAAGACCTGCAGAGTGTATGACACATAACCAGCACCCAAGAAATGTCTACCGAGGAATT
AATGAATGAGGAAATACCTCTGTACACTCACCAGACACTGGCTGCTGGTTGTCACGGTGCTAAGAGCTGTGGGAAACATGAAGAGCAATG
AGACCAGGTCCCTGCTCTGAGGAGACGTGTGCCAGCGAAGTTTCTCTCCCACGTGAGTGTGCTACAAGAAAATCTGAACCCGAGAATCTG
ATTCAGTAGGTCTGCACTTTCTCCACTTTGCCAGATAATTCTGATTGAGACCGTCAAGGCTGTGACTAGTGGGGAGGCAGTAGAGTATTT
TCTGTGCTAGACTGAGGCAGCCCTGAAGCACTGCGCAAGCACATGGAAAAGAGAAACGAGATTGGGCCGGGCACGGTGGCTCATGCCTGG
AATCTTTGGGAGGCCACGGATCACTTGAGGACAGGGGTTTGAGACCAGCTTGGCCAACATGGTGAAACCTTGTCCCTACTAAAAATACAA
AAATTAGCAGGGAGTGGTGGTGCACACCTGTAATCCCAGCTACTCTGGAGGCTGAGGCAAAAGAATCGCTTGAACCCGGGAGGTGGAGGT
TGCAGTGAGCTGAGATTGGACCACTGCCCTCCAGCCTGGGTGATAGAGTGAGACTCCATCTCT

>58586_58586_6_NEMF-C14orf182_NEMF_chr14_50312858_ENST00000546046_C14orf182_chr14_50459591_ENST00000399206_length(amino acids)=173AA_BP=119
MKSRFSTIDLRAVLAELNASLLGMRVNNVYDVDNKTYLIRLQKPDFKATLLLESGIRIHTTEFEWPKNMMPSSFAMKCRKHLKSRRLVSA
KQLGVDRIVDFQFGSDEAAYHLIIELYDREKELCHEKWKTPEKLFQRQESSRQAGLGKILPARPAECMTHNQHPRNVYRGINE

--------------------------------------------------------------

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Fusion Gene PPI Analysis for NEMF-LINC01588


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for NEMF-LINC01588


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for NEMF-LINC01588


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneNEMFC1510586Autism Spectrum Disorders1CTD_human