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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:CD22-CADPS (FusionGDB2 ID:HG933TG8618)

Fusion Gene Summary for CD22-CADPS

check button Fusion gene summary
Fusion gene informationFusion gene name: CD22-CADPS
Fusion gene ID: hg933tg8618
HgeneTgene
Gene symbol

CD22

CADPS

Gene ID

933

8618

Gene nameCD22 moleculecalcium dependent secretion activator
SynonymsSIGLEC-2|SIGLEC2CADPS1|CAPS|CAPS1|UNC-31
Cytomap('CD22')('CADPS')

19q13.12

3p14.2

Type of geneprotein-codingprotein-coding
DescriptionB-cell receptor CD22B-lymphocyte cell adhesion moleculeBL-CAMCD22 antigenT-cell surface antigen Leu-14sialic acid-binding Ig-like lectin 2calcium-dependent secretion activator 1CAPS-1Ca++-dependent secretion activatorCa2+ dependent secretion activatorCa2+-dependent activator protein for secretionCa2+-regulated cytoskeletal proteincalcium-dependent activator protein for secretion 1
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000595419, ENST00000085219, 
ENST00000270311, ENST00000341773, 
ENST00000419549, ENST00000536635, 
ENST00000544992, ENST00000594250, 
Fusion gene scores* DoF score3 X 2 X 2=126 X 5 X 5=150
# samples 47
** MAII scorelog2(4/12*10)=1.73696559416621
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(7/150*10)=-1.09953567355091
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: CD22 [Title/Abstract] AND CADPS [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCD22(35820133)-CADPS(62751659), # samples:3
Anticipated loss of major functional domain due to fusion event.CD22-CADPS seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
CD22-CADPS seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
CD22-CADPS seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
CD22-CADPS seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
CD22-CADPS seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneCD22

GO:0030100

regulation of endocytosis

17562860

HgeneCD22

GO:0042113

B cell activation

26017478

HgeneCD22

GO:0050859

negative regulation of B cell receptor signaling pathway

26017478


check buttonFusion gene breakpoints across CD22 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across CADPS (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4OVTCGA-25-1870-01ACD22chr19

35820133

+CADPSchr3

62751659

-
ChimerDB4OVTCGA-25-1870-01ACD22chr19

35823827

+CADPSchr3

62751659

-
ChimerDB4OVTCGA-25-1870CD22chr19

35820133

+CADPSchr3

62751659

-
ChimerDB4OVTCGA-25-1870CD22chr19

35823827

+CADPSchr3

62751659

-


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Fusion Gene ORF analysis for CD22-CADPS

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000595419ENST00000283269CD22chr19

35820133

+CADPSchr3

62751659

-
3UTR-3CDSENST00000595419ENST00000283269CD22chr19

35823827

+CADPSchr3

62751659

-
3UTR-3CDSENST00000595419ENST00000357948CD22chr19

35820133

+CADPSchr3

62751659

-
3UTR-3CDSENST00000595419ENST00000357948CD22chr19

35823827

+CADPSchr3

62751659

-
3UTR-3CDSENST00000595419ENST00000383710CD22chr19

35820133

+CADPSchr3

62751659

-
3UTR-3CDSENST00000595419ENST00000383710CD22chr19

35823827

+CADPSchr3

62751659

-
3UTR-3CDSENST00000595419ENST00000490353CD22chr19

35820133

+CADPSchr3

62751659

-
3UTR-3CDSENST00000595419ENST00000490353CD22chr19

35823827

+CADPSchr3

62751659

-
3UTR-intronENST00000595419ENST00000462768CD22chr19

35820133

+CADPSchr3

62751659

-
3UTR-intronENST00000595419ENST00000462768CD22chr19

35823827

+CADPSchr3

62751659

-
5CDS-intronENST00000085219ENST00000462768CD22chr19

35823827

+CADPSchr3

62751659

-
5CDS-intronENST00000270311ENST00000462768CD22chr19

35823827

+CADPSchr3

62751659

-
5CDS-intronENST00000341773ENST00000462768CD22chr19

35823827

+CADPSchr3

62751659

-
5CDS-intronENST00000419549ENST00000462768CD22chr19

35823827

+CADPSchr3

62751659

-
5CDS-intronENST00000536635ENST00000462768CD22chr19

35823827

+CADPSchr3

62751659

-
5CDS-intronENST00000544992ENST00000462768CD22chr19

35823827

+CADPSchr3

62751659

-
5CDS-intronENST00000594250ENST00000462768CD22chr19

35823827

+CADPSchr3

62751659

-
5UTR-3CDSENST00000085219ENST00000283269CD22chr19

35820133

+CADPSchr3

62751659

-
5UTR-3CDSENST00000085219ENST00000357948CD22chr19

35820133

+CADPSchr3

62751659

-
5UTR-3CDSENST00000085219ENST00000383710CD22chr19

35820133

+CADPSchr3

62751659

-
5UTR-3CDSENST00000085219ENST00000490353CD22chr19

35820133

+CADPSchr3

62751659

-
5UTR-3CDSENST00000270311ENST00000283269CD22chr19

35820133

+CADPSchr3

62751659

-
5UTR-3CDSENST00000270311ENST00000357948CD22chr19

35820133

+CADPSchr3

62751659

-
5UTR-3CDSENST00000270311ENST00000383710CD22chr19

35820133

+CADPSchr3

62751659

-
5UTR-3CDSENST00000270311ENST00000490353CD22chr19

35820133

+CADPSchr3

62751659

-
5UTR-3CDSENST00000341773ENST00000283269CD22chr19

35820133

+CADPSchr3

62751659

-
5UTR-3CDSENST00000341773ENST00000357948CD22chr19

35820133

+CADPSchr3

62751659

-
5UTR-3CDSENST00000341773ENST00000383710CD22chr19

35820133

+CADPSchr3

62751659

-
5UTR-3CDSENST00000341773ENST00000490353CD22chr19

35820133

+CADPSchr3

62751659

-
5UTR-3CDSENST00000419549ENST00000283269CD22chr19

35820133

+CADPSchr3

62751659

-
5UTR-3CDSENST00000419549ENST00000357948CD22chr19

35820133

+CADPSchr3

62751659

-
5UTR-3CDSENST00000419549ENST00000383710CD22chr19

35820133

+CADPSchr3

62751659

-
5UTR-3CDSENST00000419549ENST00000490353CD22chr19

35820133

+CADPSchr3

62751659

-
5UTR-3CDSENST00000536635ENST00000283269CD22chr19

35820133

+CADPSchr3

62751659

-
5UTR-3CDSENST00000536635ENST00000357948CD22chr19

35820133

+CADPSchr3

62751659

-
5UTR-3CDSENST00000536635ENST00000383710CD22chr19

35820133

+CADPSchr3

62751659

-
5UTR-3CDSENST00000536635ENST00000490353CD22chr19

35820133

+CADPSchr3

62751659

-
5UTR-3CDSENST00000544992ENST00000283269CD22chr19

35820133

+CADPSchr3

62751659

-
5UTR-3CDSENST00000544992ENST00000357948CD22chr19

35820133

+CADPSchr3

62751659

-
5UTR-3CDSENST00000544992ENST00000383710CD22chr19

35820133

+CADPSchr3

62751659

-
5UTR-3CDSENST00000544992ENST00000490353CD22chr19

35820133

+CADPSchr3

62751659

-
5UTR-intronENST00000085219ENST00000462768CD22chr19

35820133

+CADPSchr3

62751659

-
5UTR-intronENST00000270311ENST00000462768CD22chr19

35820133

+CADPSchr3

62751659

-
5UTR-intronENST00000341773ENST00000462768CD22chr19

35820133

+CADPSchr3

62751659

-
5UTR-intronENST00000419549ENST00000462768CD22chr19

35820133

+CADPSchr3

62751659

-
5UTR-intronENST00000536635ENST00000462768CD22chr19

35820133

+CADPSchr3

62751659

-
5UTR-intronENST00000544992ENST00000462768CD22chr19

35820133

+CADPSchr3

62751659

-
Frame-shiftENST00000085219ENST00000283269CD22chr19

35823827

+CADPSchr3

62751659

-
Frame-shiftENST00000085219ENST00000357948CD22chr19

35823827

+CADPSchr3

62751659

-
Frame-shiftENST00000085219ENST00000383710CD22chr19

35823827

+CADPSchr3

62751659

-
Frame-shiftENST00000085219ENST00000490353CD22chr19

35823827

+CADPSchr3

62751659

-
Frame-shiftENST00000270311ENST00000283269CD22chr19

35823827

+CADPSchr3

62751659

-
Frame-shiftENST00000270311ENST00000357948CD22chr19

35823827

+CADPSchr3

62751659

-
Frame-shiftENST00000270311ENST00000383710CD22chr19

35823827

+CADPSchr3

62751659

-
Frame-shiftENST00000270311ENST00000490353CD22chr19

35823827

+CADPSchr3

62751659

-
Frame-shiftENST00000341773ENST00000283269CD22chr19

35823827

+CADPSchr3

62751659

-
Frame-shiftENST00000341773ENST00000357948CD22chr19

35823827

+CADPSchr3

62751659

-
Frame-shiftENST00000341773ENST00000383710CD22chr19

35823827

+CADPSchr3

62751659

-
Frame-shiftENST00000341773ENST00000490353CD22chr19

35823827

+CADPSchr3

62751659

-
Frame-shiftENST00000536635ENST00000283269CD22chr19

35823827

+CADPSchr3

62751659

-
Frame-shiftENST00000536635ENST00000357948CD22chr19

35823827

+CADPSchr3

62751659

-
Frame-shiftENST00000536635ENST00000383710CD22chr19

35823827

+CADPSchr3

62751659

-
Frame-shiftENST00000536635ENST00000490353CD22chr19

35823827

+CADPSchr3

62751659

-
Frame-shiftENST00000544992ENST00000283269CD22chr19

35823827

+CADPSchr3

62751659

-
Frame-shiftENST00000544992ENST00000357948CD22chr19

35823827

+CADPSchr3

62751659

-
Frame-shiftENST00000544992ENST00000383710CD22chr19

35823827

+CADPSchr3

62751659

-
Frame-shiftENST00000544992ENST00000490353CD22chr19

35823827

+CADPSchr3

62751659

-
Frame-shiftENST00000594250ENST00000283269CD22chr19

35823827

+CADPSchr3

62751659

-
Frame-shiftENST00000594250ENST00000357948CD22chr19

35823827

+CADPSchr3

62751659

-
Frame-shiftENST00000594250ENST00000383710CD22chr19

35823827

+CADPSchr3

62751659

-
Frame-shiftENST00000594250ENST00000490353CD22chr19

35823827

+CADPSchr3

62751659

-
In-frameENST00000419549ENST00000283269CD22chr19

35823827

+CADPSchr3

62751659

-
In-frameENST00000419549ENST00000357948CD22chr19

35823827

+CADPSchr3

62751659

-
In-frameENST00000419549ENST00000383710CD22chr19

35823827

+CADPSchr3

62751659

-
In-frameENST00000419549ENST00000490353CD22chr19

35823827

+CADPSchr3

62751659

-
intron-3CDSENST00000594250ENST00000283269CD22chr19

35820133

+CADPSchr3

62751659

-
intron-3CDSENST00000594250ENST00000357948CD22chr19

35820133

+CADPSchr3

62751659

-
intron-3CDSENST00000594250ENST00000383710CD22chr19

35820133

+CADPSchr3

62751659

-
intron-3CDSENST00000594250ENST00000490353CD22chr19

35820133

+CADPSchr3

62751659

-
intron-intronENST00000594250ENST00000462768CD22chr19

35820133

+CADPSchr3

62751659

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000419549CD22chr1935823827+ENST00000383710CADPSchr362751659-507139135240111219
ENST00000419549CD22chr1935823827+ENST00000357948CADPSchr362751659-483139135237741140
ENST00000419549CD22chr1935823827+ENST00000283269CADPSchr362751659-432939135238941180
ENST00000419549CD22chr1935823827+ENST00000490353CADPSchr362751659-26193913521323323

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000419549ENST00000383710CD22chr1935823827+CADPSchr362751659-0.0003557860.99964416
ENST00000419549ENST00000357948CD22chr1935823827+CADPSchr362751659-0.0005102640.99948967
ENST00000419549ENST00000283269CD22chr1935823827+CADPSchr362751659-0.0009925220.9990075
ENST00000419549ENST00000490353CD22chr1935823827+CADPSchr362751659-0.0012398520.9987601

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Fusion Genomic Features for CD22-CADPS


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

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Fusion Protein Features for CD22-CADPS


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr19:35820133/chr3:62751659)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCD22chr19:35823827chr3:62751659ENST00000085219+31420_138137848.0DomainNote=Ig-like V-type
HgeneCD22chr19:35823827chr3:62751659ENST00000341773+31220_138137671.0DomainNote=Ig-like V-type
HgeneCD22chr19:35823827chr3:62751659ENST00000536635+31320_138137760.0DomainNote=Ig-like V-type
HgeneCD22chr19:35823827chr3:62751659ENST00000544992+31320_138137867.0DomainNote=Ig-like V-type
HgeneCD22chr19:35823827chr3:62751659ENST00000594250+21120_138137671.0DomainNote=Ig-like V-type
TgeneCADPSchr19:35823827chr3:62751659ENST00000283269028380_4951471315.0DomainC2
TgeneCADPSchr19:35823827chr3:62751659ENST00000283269028521_6241471315.0DomainPH
TgeneCADPSchr19:35823827chr3:62751659ENST00000283269028931_11111471315.0DomainMHD1
TgeneCADPSchr19:35823827chr3:62751659ENST00000357948027380_4951471275.0DomainC2
TgeneCADPSchr19:35823827chr3:62751659ENST00000357948027521_6241471275.0DomainPH
TgeneCADPSchr19:35823827chr3:62751659ENST00000357948027931_11111471275.0DomainMHD1
TgeneCADPSchr19:35823827chr3:62751659ENST00000383710030380_4951471354.0DomainC2
TgeneCADPSchr19:35823827chr3:62751659ENST00000383710030521_6241471354.0DomainPH
TgeneCADPSchr19:35823827chr3:62751659ENST00000383710030931_11111471354.0DomainMHD1
TgeneCADPSchr19:35823827chr3:62751659ENST0000049035307380_495147458.0DomainC2
TgeneCADPSchr19:35823827chr3:62751659ENST0000049035307521_624147458.0DomainPH
TgeneCADPSchr19:35823827chr3:62751659ENST0000049035307931_1111147458.0DomainMHD1
TgeneCADPSchr19:35823827chr3:62751659ENST000002832690281177_13531471315.0RegionMediates targeting and association with DCVs
TgeneCADPSchr19:35823827chr3:62751659ENST000003579480271177_13531471275.0RegionMediates targeting and association with DCVs
TgeneCADPSchr19:35823827chr3:62751659ENST000003837100301177_13531471354.0RegionMediates targeting and association with DCVs
TgeneCADPSchr19:35823827chr3:62751659ENST00000490353071177_1353147458.0RegionMediates targeting and association with DCVs

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCD22chr19:35823827chr3:62751659ENST00000085219+314143_235137848.0DomainNote=Ig-like C2-type 1
HgeneCD22chr19:35823827chr3:62751659ENST00000085219+314242_326137848.0DomainNote=Ig-like C2-type 2
HgeneCD22chr19:35823827chr3:62751659ENST00000085219+314331_416137848.0DomainNote=Ig-like C2-type 3
HgeneCD22chr19:35823827chr3:62751659ENST00000085219+314419_500137848.0DomainNote=Ig-like C2-type 4
HgeneCD22chr19:35823827chr3:62751659ENST00000085219+314505_582137848.0DomainNote=Ig-like C2-type 5
HgeneCD22chr19:35823827chr3:62751659ENST00000085219+314593_676137848.0DomainNote=Ig-like C2-type 6
HgeneCD22chr19:35823827chr3:62751659ENST00000341773+312143_235137671.0DomainNote=Ig-like C2-type 1
HgeneCD22chr19:35823827chr3:62751659ENST00000341773+312242_326137671.0DomainNote=Ig-like C2-type 2
HgeneCD22chr19:35823827chr3:62751659ENST00000341773+312331_416137671.0DomainNote=Ig-like C2-type 3
HgeneCD22chr19:35823827chr3:62751659ENST00000341773+312419_500137671.0DomainNote=Ig-like C2-type 4
HgeneCD22chr19:35823827chr3:62751659ENST00000341773+312505_582137671.0DomainNote=Ig-like C2-type 5
HgeneCD22chr19:35823827chr3:62751659ENST00000341773+312593_676137671.0DomainNote=Ig-like C2-type 6
HgeneCD22chr19:35823827chr3:62751659ENST00000536635+313143_235137760.0DomainNote=Ig-like C2-type 1
HgeneCD22chr19:35823827chr3:62751659ENST00000536635+313242_326137760.0DomainNote=Ig-like C2-type 2
HgeneCD22chr19:35823827chr3:62751659ENST00000536635+313331_416137760.0DomainNote=Ig-like C2-type 3
HgeneCD22chr19:35823827chr3:62751659ENST00000536635+313419_500137760.0DomainNote=Ig-like C2-type 4
HgeneCD22chr19:35823827chr3:62751659ENST00000536635+313505_582137760.0DomainNote=Ig-like C2-type 5
HgeneCD22chr19:35823827chr3:62751659ENST00000536635+313593_676137760.0DomainNote=Ig-like C2-type 6
HgeneCD22chr19:35823827chr3:62751659ENST00000544992+313143_235137867.0DomainNote=Ig-like C2-type 1
HgeneCD22chr19:35823827chr3:62751659ENST00000544992+313242_326137867.0DomainNote=Ig-like C2-type 2
HgeneCD22chr19:35823827chr3:62751659ENST00000544992+313331_416137867.0DomainNote=Ig-like C2-type 3
HgeneCD22chr19:35823827chr3:62751659ENST00000544992+313419_500137867.0DomainNote=Ig-like C2-type 4
HgeneCD22chr19:35823827chr3:62751659ENST00000544992+313505_582137867.0DomainNote=Ig-like C2-type 5
HgeneCD22chr19:35823827chr3:62751659ENST00000544992+313593_676137867.0DomainNote=Ig-like C2-type 6
HgeneCD22chr19:35823827chr3:62751659ENST00000594250+211143_235137671.0DomainNote=Ig-like C2-type 1
HgeneCD22chr19:35823827chr3:62751659ENST00000594250+211242_326137671.0DomainNote=Ig-like C2-type 2
HgeneCD22chr19:35823827chr3:62751659ENST00000594250+211331_416137671.0DomainNote=Ig-like C2-type 3
HgeneCD22chr19:35823827chr3:62751659ENST00000594250+211419_500137671.0DomainNote=Ig-like C2-type 4
HgeneCD22chr19:35823827chr3:62751659ENST00000594250+211505_582137671.0DomainNote=Ig-like C2-type 5
HgeneCD22chr19:35823827chr3:62751659ENST00000594250+211593_676137671.0DomainNote=Ig-like C2-type 6
HgeneCD22chr19:35823827chr3:62751659ENST00000085219+314760_765137848.0MotifNote=ITIM motif 1
HgeneCD22chr19:35823827chr3:62751659ENST00000085219+314794_799137848.0MotifNote=ITIM motif 2
HgeneCD22chr19:35823827chr3:62751659ENST00000085219+314820_825137848.0MotifNote=ITIM motif 3
HgeneCD22chr19:35823827chr3:62751659ENST00000085219+314840_845137848.0MotifNote=ITIM motif 4
HgeneCD22chr19:35823827chr3:62751659ENST00000341773+312760_765137671.0MotifNote=ITIM motif 1
HgeneCD22chr19:35823827chr3:62751659ENST00000341773+312794_799137671.0MotifNote=ITIM motif 2
HgeneCD22chr19:35823827chr3:62751659ENST00000341773+312820_825137671.0MotifNote=ITIM motif 3
HgeneCD22chr19:35823827chr3:62751659ENST00000341773+312840_845137671.0MotifNote=ITIM motif 4
HgeneCD22chr19:35823827chr3:62751659ENST00000536635+313760_765137760.0MotifNote=ITIM motif 1
HgeneCD22chr19:35823827chr3:62751659ENST00000536635+313794_799137760.0MotifNote=ITIM motif 2
HgeneCD22chr19:35823827chr3:62751659ENST00000536635+313820_825137760.0MotifNote=ITIM motif 3
HgeneCD22chr19:35823827chr3:62751659ENST00000536635+313840_845137760.0MotifNote=ITIM motif 4
HgeneCD22chr19:35823827chr3:62751659ENST00000544992+313760_765137867.0MotifNote=ITIM motif 1
HgeneCD22chr19:35823827chr3:62751659ENST00000544992+313794_799137867.0MotifNote=ITIM motif 2
HgeneCD22chr19:35823827chr3:62751659ENST00000544992+313820_825137867.0MotifNote=ITIM motif 3
HgeneCD22chr19:35823827chr3:62751659ENST00000544992+313840_845137867.0MotifNote=ITIM motif 4
HgeneCD22chr19:35823827chr3:62751659ENST00000594250+211760_765137671.0MotifNote=ITIM motif 1
HgeneCD22chr19:35823827chr3:62751659ENST00000594250+211794_799137671.0MotifNote=ITIM motif 2
HgeneCD22chr19:35823827chr3:62751659ENST00000594250+211820_825137671.0MotifNote=ITIM motif 3
HgeneCD22chr19:35823827chr3:62751659ENST00000594250+211840_845137671.0MotifNote=ITIM motif 4
HgeneCD22chr19:35823827chr3:62751659ENST00000085219+31420_687137848.0Topological domainExtracellular
HgeneCD22chr19:35823827chr3:62751659ENST00000085219+314707_847137848.0Topological domainCytoplasmic
HgeneCD22chr19:35823827chr3:62751659ENST00000341773+31220_687137671.0Topological domainExtracellular
HgeneCD22chr19:35823827chr3:62751659ENST00000341773+312707_847137671.0Topological domainCytoplasmic
HgeneCD22chr19:35823827chr3:62751659ENST00000536635+31320_687137760.0Topological domainExtracellular
HgeneCD22chr19:35823827chr3:62751659ENST00000536635+313707_847137760.0Topological domainCytoplasmic
HgeneCD22chr19:35823827chr3:62751659ENST00000544992+31320_687137867.0Topological domainExtracellular
HgeneCD22chr19:35823827chr3:62751659ENST00000544992+313707_847137867.0Topological domainCytoplasmic
HgeneCD22chr19:35823827chr3:62751659ENST00000594250+21120_687137671.0Topological domainExtracellular
HgeneCD22chr19:35823827chr3:62751659ENST00000594250+211707_847137671.0Topological domainCytoplasmic
HgeneCD22chr19:35823827chr3:62751659ENST00000085219+314688_706137848.0TransmembraneHelical
HgeneCD22chr19:35823827chr3:62751659ENST00000341773+312688_706137671.0TransmembraneHelical
HgeneCD22chr19:35823827chr3:62751659ENST00000536635+313688_706137760.0TransmembraneHelical
HgeneCD22chr19:35823827chr3:62751659ENST00000544992+313688_706137867.0TransmembraneHelical
HgeneCD22chr19:35823827chr3:62751659ENST00000594250+211688_706137671.0TransmembraneHelical


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Fusion Gene Sequence for CD22-CADPS


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>14412_14412_1_CD22-CADPS_CD22_chr19_35823827_ENST00000419549_CADPS_chr3_62751659_ENST00000283269_length(transcript)=4329nt_BP=391nt
GGAAGACACGCGGAAACAGAATACTTGGCTTTCTCTGACTCAAGTAAATGGGTTTTTGAGCACCCTGAAACCCTCTACGCCTGGGAGGGG
GCCTGCGTCTGGATCCCCTGCACCTACAGAGCCCTAGATGGTGACCTGGAAAGCTTCATCCTGTTCCACAATCCTGAGTATAACAAGAAC
ACCTCGAAGTTTGATGGGACAAGACTCTATGAAAGCACAAAGGATGGGAAGGTTCCTTCTGAGCAGAAAAGGGTGCAATTCCTGGGAGAC
AAGAATAAGAACTGCACACTGAGTATCCACCCGGTGCACCTCAATGACAGTGGTCAGCTGGGGCTGAGGATGGAGTCCAAGACTGAGAAA
TGGATGGAACGAATACACCTCAATGTCTCTGATCAGCAAACAGCAGCTGCAGACAGTCAAGGACCGGTTTCAGGCTTTCCTCAATGGGGA
AACCCAGATCATGGCTGACGAAGCCTTCATGAACGCTGTGCAGAGTTACTATGAGGTGTTCCTGAAGAGCGACCGTGTGGCCCGCATGGT
TCAGAGTGGAGGCTGTTCCGCCAACGACTCCCGGGAGGTCTTCAAGAAGCACATTGAGAAGAGAGTGCGCAGCCTGCCTGAGATTGACGG
CCTCAGCAAGGAGACTGTGCTGAGCTCCTGGATGGCCAAATTTGATGCCATCTACCGTGGAGAAGAGGACCCGCGGAAGCAGCAGGCCCG
GATGACAGCCAGCGCAGCCTCCGAGCTGATTCTGAGCAAGGAGCAACTCTATGAGATGTTCCAGAACATTCTTGGGATCAAGAAGTTCGA
ACATCAGCTCCTTTACAATGCCTGCCAGCTGGACAATCCAGATGAGCAAGCAGCCCAGATCAGACGAGAGCTGGATGGACGTCTACAAAT
GGCAGACCAAATAGCCAGGGAACGCAAATTTCCCAAGTTTGTATCCAAAGAAATGGAAAACATGTACATTGAGGAGCTGAAGTCATCTGT
CAACCTGCTCATGGCCAACTTGGAGAGCATGCCGGTATCCAAAGGCGGGGAGTTCAAGCTCCAGAAACTCAAACGCAGCCACAATGCTTC
CATCATCGACATGGGCGAGGAGAGTGAGAACCAGCTCTCCAAGTCAGATGTCGTGCTGTCTTTCTCATTGGAGGTGGTAATTATGGAAGT
CCAAGGCCTCAAATCTTTGGCTCCAAATCGCATCGTATATTGCACAATGGAGGTGGAAGGAGGAGAGAAACTACAGACTGATCAGGCCGA
GGCTTCTAAACCAACCTGGGGCACCCAGGGTGACTTCTCCACAACCCATGCACTGCCAGCTGTGAAGGTGAAGCTGTTCACAGAGAGCAC
AGGCGTCCTGGCGTTGGAGGACAAGGAGCTTGGGCGGGTTATTCTCCATCCCACCCCGAACAGCCCCAAACAGTCAGAGTGGCACAAAAT
GACAGTCTCCAAAAACTGCCCCGACCAAGATCTCAAAATCAAACTTGCTGTCCGAATGGATAAGCCTCAAAACATGAAGCATTCTGGGTA
TTTATGGGCCATCGGTAAGAATGTCTGGAAGAGATGGAAGAAAAGGTTTTTTGTATTGGTGCAGGTCAGTCAGTACACGTTTGCCATGTG
CAGTTATCGGGAGAAGAAAGCGGAGCCTCAGGAACTTCTACAATTGGATGGCTACACTGTGGATTACACCGACCCCCAGCCAGGTTTGGA
GGGTGGCCGAGCCTTCTTCAATGCTGTCAAGGAGGGAGACACCGTGATATTTGCCAGTGACGATGAACAAGACCGCATCCTGTGGGTCCA
GGCCATGTATCGGGCCACGGGGCAGTCACACAAGCCTGTGCCCCCGACCCAAGTCCAGAAACTCAACGCCAAGGGAGGAAATGTACCTCA
GCTGGATGCCCCTATCTCTCAATTTTACGCAGATAGAGCTCAAAAACATGGCATGGATGAATTTATCTCTTCCAACCCCTGTAACTTTGA
CCACGCTTCCCTCTTTGAGATGGTACAACGCCTTACTTTGGATCACAGACTTAATGATTCCTATTCTTGCCTGGGCTGGTTCAGTCCTGG
CCAGGTGTTTGTACTAGACGAGTATTGCGCCCGAAATGGAGTCCGGGGGTGTCACCGACATCTCTGCTACCTCAGAGACTTGCTTGAACG
GGCAGAAAATGGCGCCATGATCGACCCCACCCTTCTTCACTACAGCTTTGCCTTCTGTGCATCCCATGTCCATGGGAACAGGCCTGATGG
AATTGGAACTGTGACTGTTGAAGAAAAGGAACGTTTTGAAGAAATCAAAGAGAGGCTCCGAGTTCTGCTAGAAAATCAGATTACACATTT
TAGGTATTGCTTTCCATTTGGTCGACCTGAAGGTGCTTTGAAAGCTACTCTCTCACTCTTGGAAAGGGTTTTGATGAAAGATATTGTTAC
CCCAGTGCCACAAGAGGAGGTAAAAACAGTTATCCGTAAATGTCTGGAACAGGCTGCGTTAGTCAACTATTCTCGGCTCTCAGAGTATGC
CAAAATCGAAGGGAAAAAGAGAGAAATGTATGAGCATCCTGTCTTCTGCTTGGCCTCCCAAGTGATGGATTTAACCATTCAAAATGTAGG
CCGGTTAATCACTCCTGCCAAAAAGCTTGAAGATACAATACGTCTTGCTGAACTAGTCATTGAAGTTCTTCAGCAAAATGAGGAGCACCA
CGCAGAGGCCTTTGCGTGGTGGTCAGATTTAATGGTGGAGCATGCGGAGACGTTCCTGTCACTCTTTGCAGTAGACATGGATGCAGCCTT
AGAGGTGCAACCTCCAGACACATGGGACAGTTTTCCACTATTTCAGCTGCTGAATGATTTTCTCCGTACTGACTATAATTTGTGCAATGG
AAAATTTCACAAACACCTGCAAGACCTGTTTGCCCCACTTGTTGTTAGATATGTGGATCTGATGGAGTCCTCAATTGCACAATCCATTCA
CAGGGGCTTTGAGCGGGAGTCATGGGAACCAGTCAATAATGGGTCAGGCACCTCAGAAGATCTGTTTTGGAAACTTGACGCCCTTCAGAC
CTTCATTCGGGACCTGCACTGGCCTGAAGAAGAGTTTGGAAAGCACCTGGAACAACGGCTGAAGTTGATGGCAAGTGACATGATCGAATC
TTGTGTCAAAAGAACCAGGATTGCATTTGAAGTTAAGCTGCAAAAAACCAGTCGATCAACAGATTTTCGAGTCCCACAGTCAATATGCAC
CATGTTTAATGTTATGGTTGATGCCAAAGCTCAATCAACAAAACTTTGCAGCATGGAAATGGGCCAAGAGCATCAATACCATTCAAAAAT
AGACGAACTAATTGAAGAAACTGTTAAAGAAATGATAACACTCTTGGTTGCAAAGTTCGTTACTATCTTGGAAGGAGTGCTGGCAAAATT
ATCCAGATATGACGAAGGGACTTTGTTTTCTTCTTTTCTGTCATTTACCGTGAAGGCAGCTTCCAAATATGTGGATGTACCTAAACCCGG
GATGGACGTGGCCGACGCCTACGTGACTTTCGTCCGCCATTCTCAGGATGTCCTGCGTGATAAGGTCAATGAGGAGATGTACATAGAAAG
GTTATTTGATCAATGGTACAACAGCTCCATGAACGTGATCTGCACCTGGTTGACGGACCGGATGGACTTACAGCTTCATATTTATCAGTT
GAAAACACTAATTAGGATGGTAAAGAAAACCTACAGAGATTTCCGATTGCAAGGGGTCCTGGACTCCACCTTAAACAGCAAGACCTATGA
AACGATCCGGAACCGTCTCACTGTGGAGGAAGCCACAGCATCAGTGAGTGAAGGTGGGGGACTGCAGGGCATCAGCATGAAGGACAGCGA
TGAGGAAGACGAAGAAGACGATTAGACCATTTGGTCCTAGAGTCTGCTGGGACAGAGTCCTGTAATCAGTGCATGTCCTTAGTCTGTTAG
TTAAACCCATTAGGAATTTTCTGTCAACTACCATGCCCATGAGATGTTTATCAATACAACTGCCATTTTAGCTATGTGGTACCAAGATTA
GCAAATGACCTTCATATCCACTGATTTCCTGATGTCCATGTCTATATGTTTACAAGCAATATGGAGCACCATTCTTTAAATACTGTTCAT
GGAGAATACATAGTCTAACCACTAGGCGTGTCCCTGTTATCAGCAAAGATCAATGATGCTTCATTCATGTACTATGTATGCATTGGTGGT
AAATGGATGTGAGGGCAAGTACATCAAGTACATTCACTCTGTTTCACGTATGTGGATGCCAGTTAATTAAATGAGTACGTAAATAAATTA
ATTAAAACA

>14412_14412_1_CD22-CADPS_CD22_chr19_35823827_ENST00000419549_CADPS_chr3_62751659_ENST00000283269_length(amino acids)=1180AA_BP=13
MRNGWNEYTSMSLISKQQLQTVKDRFQAFLNGETQIMADEAFMNAVQSYYEVFLKSDRVARMVQSGGCSANDSREVFKKHIEKRVRSLPE
IDGLSKETVLSSWMAKFDAIYRGEEDPRKQQARMTASAASELILSKEQLYEMFQNILGIKKFEHQLLYNACQLDNPDEQAAQIRRELDGR
LQMADQIARERKFPKFVSKEMENMYIEELKSSVNLLMANLESMPVSKGGEFKLQKLKRSHNASIIDMGEESENQLSKSDVVLSFSLEVVI
MEVQGLKSLAPNRIVYCTMEVEGGEKLQTDQAEASKPTWGTQGDFSTTHALPAVKVKLFTESTGVLALEDKELGRVILHPTPNSPKQSEW
HKMTVSKNCPDQDLKIKLAVRMDKPQNMKHSGYLWAIGKNVWKRWKKRFFVLVQVSQYTFAMCSYREKKAEPQELLQLDGYTVDYTDPQP
GLEGGRAFFNAVKEGDTVIFASDDEQDRILWVQAMYRATGQSHKPVPPTQVQKLNAKGGNVPQLDAPISQFYADRAQKHGMDEFISSNPC
NFDHASLFEMVQRLTLDHRLNDSYSCLGWFSPGQVFVLDEYCARNGVRGCHRHLCYLRDLLERAENGAMIDPTLLHYSFAFCASHVHGNR
PDGIGTVTVEEKERFEEIKERLRVLLENQITHFRYCFPFGRPEGALKATLSLLERVLMKDIVTPVPQEEVKTVIRKCLEQAALVNYSRLS
EYAKIEGKKREMYEHPVFCLASQVMDLTIQNVGRLITPAKKLEDTIRLAELVIEVLQQNEEHHAEAFAWWSDLMVEHAETFLSLFAVDMD
AALEVQPPDTWDSFPLFQLLNDFLRTDYNLCNGKFHKHLQDLFAPLVVRYVDLMESSIAQSIHRGFERESWEPVNNGSGTSEDLFWKLDA
LQTFIRDLHWPEEEFGKHLEQRLKLMASDMIESCVKRTRIAFEVKLQKTSRSTDFRVPQSICTMFNVMVDAKAQSTKLCSMEMGQEHQYH
SKIDELIEETVKEMITLLVAKFVTILEGVLAKLSRYDEGTLFSSFLSFTVKAASKYVDVPKPGMDVADAYVTFVRHSQDVLRDKVNEEMY
IERLFDQWYNSSMNVICTWLTDRMDLQLHIYQLKTLIRMVKKTYRDFRLQGVLDSTLNSKTYETIRNRLTVEEATASVSEGGGLQGISMK
DSDEEDEEDD

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>14412_14412_2_CD22-CADPS_CD22_chr19_35823827_ENST00000419549_CADPS_chr3_62751659_ENST00000357948_length(transcript)=4831nt_BP=391nt
GGAAGACACGCGGAAACAGAATACTTGGCTTTCTCTGACTCAAGTAAATGGGTTTTTGAGCACCCTGAAACCCTCTACGCCTGGGAGGGG
GCCTGCGTCTGGATCCCCTGCACCTACAGAGCCCTAGATGGTGACCTGGAAAGCTTCATCCTGTTCCACAATCCTGAGTATAACAAGAAC
ACCTCGAAGTTTGATGGGACAAGACTCTATGAAAGCACAAAGGATGGGAAGGTTCCTTCTGAGCAGAAAAGGGTGCAATTCCTGGGAGAC
AAGAATAAGAACTGCACACTGAGTATCCACCCGGTGCACCTCAATGACAGTGGTCAGCTGGGGCTGAGGATGGAGTCCAAGACTGAGAAA
TGGATGGAACGAATACACCTCAATGTCTCTGATCAGCAAACAGCAGCTGCAGACAGTCAAGGACCGGTTTCAGGCTTTCCTCAATGGGGA
AACCCAGATCATGGCTGACGAAGCCTTCATGAACGCTGTGCAGAGTTACTATGAGGTGTTCCTGAAGAGCGACCGTGTGGCCCGCATGGT
TCAGAGTGGAGGCTGTTCCGCCAACGACTCCCGGGAGGTCTTCAAGAAGCACATTGAGAAGAGAGTGCGCAGCCTGCCTGAGATTGACGG
CCTCAGCAAGGAGACTGTGCTGAGCTCCTGGATGGCCAAATTTGATGCCATCTACCGTGGAGAAGAGGACCCGCGGAAGCAGCAGGCCCG
GATGACAGCCAGCGCAGCCTCCGAGCTGATTCTGAGCAAGGAGCAACTCTATGAGATGTTCCAGAACATTCTTGGGATCAAGAAGTTCGA
ACATCAGCTCCTTTACAATGCCTGCCAGCTGGACAATCCAGATGAGCAAGCAGCCCAGATCAGACGAGAGCTGGATGGACGTCTACAAAT
GGCAGACCAAATAGCCAGGGAACGCAAATTTCCCAAGTTTGTATCCAAAGAAATGGAAAACATGTACATTGAGGAGCTGAAGTCATCTGT
CAACCTGCTCATGGCCAACTTGGAGAGCATGCCGGTATCCAAAGGCGGGGAGTTCAAGCTCCAGAAACTCAAACGCAGCCACAATGCTTC
CATCATCGACATGGGCGAGGAGAGTGAGAACCAGCTCTCCAAGTCAGATGTCGTGCTGTCTTTCTCATTGGAGGTGGTAATTATGGAAGT
CCAAGGCCTCAAATCTTTGGCTCCAAATCGCATCGTATATTGCACAATGGAGGTGGAAGGAGGAGAGAAACTACAGACTGATCAGGCCGA
GGCTTCTAAACCAACCTGGGGCACCCAGGGTGACTTCTCCACAACCCATGCACTGCCAGCTGTGAAGGTGAAGCTGTTCACAGAGAGCAC
AGGCGTCCTGGCGTTGGAGGACAAGGAGCTTGGGCGGGTTATTCTCCATCCCACCCCGAACAGCCCCAAACAGTCAGAGTGGCACAAAAT
GACAGTCTCCAAAAACTGCCCCGACCAAGATCTCAAAATCAAACTTGCTGTCCGAATGGATAAGCCTCAAAACATGAAGCATTCTGGGTA
TTTATGGGCCATCGGTAAGAATGTCTGGAAGAGATGGAAGAAAAGGTTTTTTGTATTGGTGCAGGTCAGTCAGTACACGTTTGCCATGTG
CAGTTATCGGGAGAAGAAAGCGGAGCCTCAGGAACTTCTACAATTGGATGGCTACACTGTGGATTACACCGACCCCCAGCCAGGTTTGGA
GGGTGGCCGAGCCTTCTTCAATGCTGTCAAGGAGGGAGACACCGTGATATTTGCCAGTGACGATGAACAAGACCGCATCCTGTGGGTCCA
GGCCATGTATCGGGCCACGGGGCAGTCACACAAGCCTGTGCCCCCGACCCAAGTCCAGAAACTCAACGCCAAGGGAGGAAATGTACCTCA
GCTGGATGCCCCTATCTCTCAATTTTACGCAGATAGAGCTCAAAAACATGGCATGGATGAATTTATCTCTTCCAACCCCTGTAACTTTGA
CCACGCTTCCCTCTTTGAGATGGGCTGGTTCAGTCCTGGCCAGGTGTTTGTACTAGACGAGTATTGCGCCCGAAATGGAGTCCGGGGGTG
TCACCGACATCTCTGCTACCTCAGAGACTTGCTTGAACGGGCAGAAAATGGCGCCATGATCGACCCCACCCTTCTTCACTACAGCTTTGC
CTTCTGTGCATCCCATGTCCATGGGAACAGGCCTGATGGAATTGGAACTGTGACTGTTGAAGAAAAGGAACGTTTTGAAGAAATCAAAGA
GAGGCTCCGAGTTCTGCTAGAAAATCAGATTACACATTTTAGGTATTGCTTTCCATTTGGTCGACCTGAAGGTGCTTTGAAAGCTACTCT
CTCACTCTTGGAAAGGGTTTTGATGAAAGATATTGTTACCCCAGTGCCACAAGAGGAGGTAAAAACAGTTATCCGTAAATGTCTGGAACA
GGCTGCGTTAGTCAACTATTCTCGGCTCTCAGAGTATGCCAAAATCGAAGAAAATGTAGGCCGGTTAATCACTCCTGCCAAAAAGCTTGA
AGATACAATACGTCTTGCTGAACTAGTCATTGAAGTTCTTCAGCAAAATGAGGAGCACCACGCAGAGGCCTTTGCGTGGTGGTCAGATTT
AATGGTGGAGCATGCGGAGACGTTCCTGTCACTCTTTGCAGTAGACATGGATGCAGCCTTAGAGGTGCAACCTCCAGACACATGGGACAG
TTTTCCACTATTTCAGCTGCTGAATGATTTTCTCCGTACTGACTATAATTTGTGCAATGGAAAATTTCACAAACACCTGCAAGACCTGTT
TGCCCCACTTGTTGTTAGATATGTGGATCTGATGGAGTCCTCAATTGCACAATCCATTCACAGGGGCTTTGAGCGGGAGTCATGGGAACC
AGTCAATAATGGGTCAGGCACCTCAGAAGATCTGTTTTGGAAACTTGACGCCCTTCAGACCTTCATTCGGGACCTGCACTGGCCTGAAGA
AGAGTTTGGAAAGCACCTGGAACAACGGCTGAAGTTGATGGCAAGTGACATGATCGAATCTTGTGTCAAAAGAACCAGGATTGCATTTGA
AGTTAAGCTGCAAAAAACCAGTCGATCAACAGATTTTCGAGTCCCACAGTCAATATGCACCATGTTTAATGTTATGGTTGATGCCAAAGC
TCAATCAACAAAACTTTGCAGCATGGAAATGGGCCAAGAGCATCAATACCATTCAAAAATAGACGAACTAATTGAAGAAACTGTTAAAGA
AATGATAACACTCTTGGTTGCAAAGTTCGTTACTATCTTGGAAGGAGTGCTGGCAAAATTATCCAGATATGACGAAGGGACTTTGTTTTC
TTCTTTTCTGTCATTTACCGTGAAGGCAGCTTCCAAATATGTGGATGTACCTAAACCCGGGATGGACGTGGCCGACGCCTACGTGACTTT
CGTCCGCCATTCTCAGGATGTCCTGCGTGATAAGGTCAATGAGGAGATGTACATAGAAAGGTTATTTGATCAATGGTACAACAGCTCCAT
GAACGTGATCTGCACCTGGTTGACGGACCGGATGGACTTACAGCTTCATATTTATCAGTTGAAAACACTAATTAGGATGGTAAAGAAAAC
CTACAGAGATTTCCGATTGCAAGGGGTCCTGGACTCCACCTTAAACAGCAAGACCTATGAAACGATCCGGAACCGTCTCACTGTGGAGGA
AGCCACAGCATCAGTGAGTGAAGGTGGGGGACTGCAGGGCATCAGCATGAAGGACAGCGATGAGGAAGACGAAGAAGACGATTAGACCAT
TTGGTCCTAGAGTCTGCTGGGACAGAGTCCTGTAATCAGTGCATGTCCTTAGTCTGTTAGTTAAACCCATTAGGAATTTTCTGTCAACTA
CCATGCCCATGAGATGTTTATCAATACAACTGCCATTTTAGCTATGTGGTACCAAGATTAGCAAATGACCTTCATATCCACTGATTTCCT
GATGTCCATGTCTATATGTTTACAAGCAATATGGAGCACCATTCTTTAAATACTGTTCATGGAGAATACATAGTCTAACCACTAGGCGTG
TCCCTGTTATCAGCAAAGATCAATGATGCTTCATTCATGTACTATGTATGCATTGGTGGTAAATGGATGTGAGGGCAAGTACATCAAGTA
CATTCACTCTGTTTCACGTATGTGGATGCCAGTTAATTAAATGAGTACGTAAATAAATTAATTAAAACACATAGATCTGCTTTGTGTTTT
TATTTTTATTTTTTGAAAAACAAAAGGCAAGTCTCCAACAATTAACTTTTGATGCTTTCTGTTCCCCTAAAACCAAAAAATGAACCCCTT
GTGTCGTTGTTAACCCATCCTTTCATTTACTCATATAATTAGCCAAAAAAAAAAGGATGGCTACATACCAATGGATTGATTCTCTTAATT
GCCACGGCAAGGGGGCGATCCTATCATGACTTAACATCAAGCGCGCAGTTCAAAACTACTGTCTTCTGTCAAAGTTTTCTCCTCTTAAAT
GTTATTTTGCTTTTACGTCTCAACTGTGTATGTAAAAAAAATGAATATTTAAATTACAACCCTAGACTAAAAATGTGTTTATAATAAGAT
GTGGATATTTCCTTCAGTAGATTGTAACCATAATTTAAATTATTTTGTTCCACACTGTTTTTTATATCTGTCATGTACATTGCATTTTGA
TCTGTAACTGCACAACCCTGGGGTTTGCTGCAGAGCTATTTCTTTCCATGTAAAGTAGTGGATCCATCTTGCTTTTGCCTTATATAAAGC
CTACAGTTATGGAAGTGTGGAAAACTGTGGCTTCTCAATAAATATTCAGATGTCCTAAGAA

>14412_14412_2_CD22-CADPS_CD22_chr19_35823827_ENST00000419549_CADPS_chr3_62751659_ENST00000357948_length(amino acids)=1140AA_BP=13
MRNGWNEYTSMSLISKQQLQTVKDRFQAFLNGETQIMADEAFMNAVQSYYEVFLKSDRVARMVQSGGCSANDSREVFKKHIEKRVRSLPE
IDGLSKETVLSSWMAKFDAIYRGEEDPRKQQARMTASAASELILSKEQLYEMFQNILGIKKFEHQLLYNACQLDNPDEQAAQIRRELDGR
LQMADQIARERKFPKFVSKEMENMYIEELKSSVNLLMANLESMPVSKGGEFKLQKLKRSHNASIIDMGEESENQLSKSDVVLSFSLEVVI
MEVQGLKSLAPNRIVYCTMEVEGGEKLQTDQAEASKPTWGTQGDFSTTHALPAVKVKLFTESTGVLALEDKELGRVILHPTPNSPKQSEW
HKMTVSKNCPDQDLKIKLAVRMDKPQNMKHSGYLWAIGKNVWKRWKKRFFVLVQVSQYTFAMCSYREKKAEPQELLQLDGYTVDYTDPQP
GLEGGRAFFNAVKEGDTVIFASDDEQDRILWVQAMYRATGQSHKPVPPTQVQKLNAKGGNVPQLDAPISQFYADRAQKHGMDEFISSNPC
NFDHASLFEMGWFSPGQVFVLDEYCARNGVRGCHRHLCYLRDLLERAENGAMIDPTLLHYSFAFCASHVHGNRPDGIGTVTVEEKERFEE
IKERLRVLLENQITHFRYCFPFGRPEGALKATLSLLERVLMKDIVTPVPQEEVKTVIRKCLEQAALVNYSRLSEYAKIEENVGRLITPAK
KLEDTIRLAELVIEVLQQNEEHHAEAFAWWSDLMVEHAETFLSLFAVDMDAALEVQPPDTWDSFPLFQLLNDFLRTDYNLCNGKFHKHLQ
DLFAPLVVRYVDLMESSIAQSIHRGFERESWEPVNNGSGTSEDLFWKLDALQTFIRDLHWPEEEFGKHLEQRLKLMASDMIESCVKRTRI
AFEVKLQKTSRSTDFRVPQSICTMFNVMVDAKAQSTKLCSMEMGQEHQYHSKIDELIEETVKEMITLLVAKFVTILEGVLAKLSRYDEGT
LFSSFLSFTVKAASKYVDVPKPGMDVADAYVTFVRHSQDVLRDKVNEEMYIERLFDQWYNSSMNVICTWLTDRMDLQLHIYQLKTLIRMV
KKTYRDFRLQGVLDSTLNSKTYETIRNRLTVEEATASVSEGGGLQGISMKDSDEEDEEDD

--------------------------------------------------------------
>14412_14412_3_CD22-CADPS_CD22_chr19_35823827_ENST00000419549_CADPS_chr3_62751659_ENST00000383710_length(transcript)=5071nt_BP=391nt
GGAAGACACGCGGAAACAGAATACTTGGCTTTCTCTGACTCAAGTAAATGGGTTTTTGAGCACCCTGAAACCCTCTACGCCTGGGAGGGG
GCCTGCGTCTGGATCCCCTGCACCTACAGAGCCCTAGATGGTGACCTGGAAAGCTTCATCCTGTTCCACAATCCTGAGTATAACAAGAAC
ACCTCGAAGTTTGATGGGACAAGACTCTATGAAAGCACAAAGGATGGGAAGGTTCCTTCTGAGCAGAAAAGGGTGCAATTCCTGGGAGAC
AAGAATAAGAACTGCACACTGAGTATCCACCCGGTGCACCTCAATGACAGTGGTCAGCTGGGGCTGAGGATGGAGTCCAAGACTGAGAAA
TGGATGGAACGAATACACCTCAATGTCTCTGATCAGCAAACAGCAGCTGCAGACAGTCAAGGACCGGTTTCAGGCTTTCCTCAATGGGGA
AACCCAGATCATGGCTGACGAAGCCTTCATGAACGCTGTGCAGAGTTACTATGAGGTGTTCCTGAAGAGCGACCGTGTGGCCCGCATGGT
TCAGAGTGGAGGCTGTTCCGCCAACGACTCCCGGGAGGTCTTCAAGAAGCACATTGAGAAGAGAGTGCGCAGCCTGCCTGAGATTGACGG
CCTCAGCAAGGAGACTGTGCTGAGCTCCTGGATGGCCAAATTTGATGCCATCTACCGTGGAGAAGAGGACCCGCGGAAGCAGCAGGCCCG
GATGACAGCCAGCGCAGCCTCCGAGCTGATTCTGAGCAAGGAGCAACTCTATGAGATGTTCCAGAACATTCTTGGGATCAAGAAGTTCGA
ACATCAGCTCCTTTACAATGCCTGCCAGCTGGACAATCCAGATGAGCAAGCAGCCCAGATCAGACGAGAGCTGGATGGACGTCTACAAAT
GGCAGACCAAATAGCCAGGGAACGCAAATTTCCCAAGTTTGTATCCAAAGAAATGGAAAACATGTACATTGAGGAGCTGAAGTCATCTGT
CAACCTGCTCATGGCCAACTTGGAGAGCATGCCGGTATCCAAAGGCGGGGAGTTCAAGCTCCAGAAACTCAAACGCAGCCACAATGCTTC
CATCATCGACATGGGCGAGGAGAGTGAGAACCAGCTCTCCAAGTCAGATGTCGTGCTGTCTTTCTCATTGGAGGTGGTAATTATGGAAGT
CCAAGGCCTCAAATCTTTGGCTCCAAATCGCATCGTATATTGCACAATGGAGGTGGAAGGAGGAGAGAAACTACAGACTGATCAGGCCGA
GGCTTCTAAACCAACCTGGGGCACCCAGGGTGACTTCTCCACAACCCATGCACTGCCAGCTGTGAAGGTGAAGCTGTTCACAGAGAGCAC
AGGCGTCCTGGCGTTGGAGGACAAGGAGCTTGGGCGGGTTATTCTCCATCCCACCCCGAACAGCCCCAAACAGTCAGAGTGGCACAAAAT
GACAGTCTCCAAAAACTGCCCCGACCAAGATCTCAAAATCAAACTTGCTGTCCGAATGGATAAGCCTCAAAACATGAAGCATTCTGGGTA
TTTATGGGCCATCGGTAAGAATGTCTGGAAGAGATGGAAGAAAAGGTTTTTTGTATTGGTGCAGGTCAGTCAGTACACGTTTGCCATGTG
CAGTTATCGGGAGAAGAAAGCGGAGCCTCAGGAACTTCTACAATTGGATGGCTACACTGTGGATTACACCGACCCCCAGCCAGGTTTGGA
GGGTGGCCGAGCCTTCTTCAATGCTGTCAAGGAGGGAGACACCGTGATATTTGCCAGTGACGATGAACAAGACCGCATCCTGTGGGTCCA
GGCCATGTATCGGGCCACGGGGCAGTCACACAAGCCTGTGCCCCCGACCCAAGTCCAGAAACTCAACGCCAAGGGAGGAAATGTACCTCA
GCTGGATGCCCCTATCTCTCAATTTTACGCAGATAGAGCTCAAAAACATGGCATGGATGAATTTATCTCTTCCAACCCCTGTAACTTTGA
CCACGCTTCCCTCTTTGAGATGGTACAACGCCTTACTTTGGATCACAGACTTAATGATTCCTATTCTTGCCTGGGCTGGTTCAGTCCTGG
CCAGGTGTTTGTACTAGACGAGTATTGCGCCCGAAATGGAGTCCGGGGGTGTCACCGACATCTCTGCTACCTCAGAGACTTGCTTGAACG
GGCAGAAAATGGCGCCATGATCGACCCCACCCTTCTTCACTACAGCTTTGCCTTCTGTGCATCCCATGTCCATGGGAACAGGCCTGATGG
AATTGGAACTGTGACTGTTGAAGAAAAGGAACGTTTTGAAGAAATCAAAGAGAGGCTCCGAGTTCTGCTAGAAAATCAGATTACACATTT
TAGGTATTGCTTTCCATTTGGTCGACCTGAAGGTGCTTTGAAAGCTACTCTCTCACTCTTGGAAAGGGTTTTGATGAAAGATATTGTTAC
CCCAGTGCCACAAGAGGAGGTAAAAACAGTTATCCGTAAATGTCTGGAACAGGCTGCGTTAGTCAACTATTCTCGGCTCTCAGAGTATGC
CAAAATCGAAGAGAATCAAAAGGATGCAGAAAATGTAGGCCGGTTAATCACTCCTGCCAAAAAGCTTGAAGATACAATACGTCTTGCTGA
ACTAGTCATTGAAGTTCTTCAGCAAAATGAGGAGCACCACGCAGAGCCACATGTTGATAAAGGAGAAGCCTTTGCGTGGTGGTCAGATTT
AATGGTGGAGCATGCGGAGACGTTCCTGTCACTCTTTGCAGTAGACATGGATGCAGCCTTAGAGGTGCAACCTCCAGACACATGGGACAG
TTTTCCACTATTTCAGCTGCTGAATGATTTTCTCCGTACTGACTATAATTTGTGCAATGGAAAATTTCACAAACACCTGCAAGACCTGTT
TGCCCCACTTGTTGTTAGATATGTGGATCTGATGGAGTCCTCAATTGCACAATCCATTCACAGGGGCTTTGAGCGGGAGTCATGGGAACC
AGTCAAGAGTTTAACCAGTAACCTACCCAATGTGAACCTACCCAATGTGAACCTTCCCAAAGTACCAAATCTACCAGTTAACATCCCTCT
AGGCATCCCACAAATGCCTACTTTTTCGGCACCGTCATGGATGGCTGCTATATATGATGCGGATAATGGGTCAGGCACCTCAGAAGATCT
GTTTTGGAAACTTGACGCCCTTCAGACCTTCATTCGGGACCTGCACTGGCCTGAAGAAGAGTTTGGAAAGCACCTGGAACAACGGCTGAA
GTTGATGGCAAGTGACATGATCGAATCTTGTGTCAAAAGAACCAGGATTGCATTTGAAGTTAAGCTGCAAAAAACCAGTCGATCAACAGA
TTTTCGAGTCCCACAGTCAATATGCACCATGTTTAATGTTATGGTTGATGCCAAAGCTCAATCAACAAAACTTTGCAGCATGGAAATGGG
CCAAGAGCATCAATACCATTCAAAAATAGACGAACTAATTGAAGAAACTGTTAAAGAAATGATAACACTCTTGGTTGCAAAGTTCGTTAC
TATCTTGGAAGGAGTGCTGGCAAAATTATCCAGATATGACGAAGGGACTTTGTTTTCTTCTTTTCTGTCATTTACCGTGAAGGCAGCTTC
CAAATATGTGGATGTACCTAAACCCGGGATGGACGTGGCCGACGCCTACGTGACTTTCGTCCGCCATTCTCAGGATGTCCTGCGTGATAA
GGTCAATGAGGAGATGTACATAGAAAGGTTATTTGATCAATGGTACAACAGCTCCATGAACGTGATCTGCACCTGGTTGACGGACCGGAT
GGACTTACAGCTTCATATTTATCAGTTGAAAACACTAATTAGGATGGTAAAGAAAACCTACAGAGATTTCCGATTGCAAGGGGTCCTGGA
CTCCACCTTAAACAGCAAGACCTATGAAACGATCCGGAACCGTCTCACTGTGGAGGAAGCCACAGCATCAGTGAGTGAAGGTGGGGGACT
GCAGGGCATCAGCATGAAGGACAGCGATGAGGAAGACGAAGAAGACGATTAGACCATTTGGTCCTAGAGTCTGCTGGGACAGAGTCCTGT
AATCAGTGCATGTCCTTAGTCTGTTAGTTAAACCCATTAGGAATTTTCTGTCAACTACCATGCCCATGAGATGTTTATCAATACAACTGC
CATTTTAGCTATGTGGTACCAAGATTAGCAAATGACCTTCATATCCACTGATTTCCTGATGTCCATGTCTATATGTTTACAAGCAATATG
GAGCACCATTCTTTAAATACTGTTCATGGAGAATACATAGTCTAACCACTAGGCGTGTCCCTGTTATCAGCAAAGATCAATGATGCTTCA
TTCATGTACTATGTATGCATTGGTGGTAAATGGATGTGAGGGCAAGTACATCAAGTACATTCACTCTGTTTCACGTATGTGGATGCCAGT
TAATTAAATGAGTACGTAAATAAATTAATTAAAACACATAGATCTGCTTTGTGTTTTTATTTTTATTTTTTGAAAAACAAAAGGCAAGTC
TCCAACAATTAACTTTTGATGCTTTCTGTTCCCCTAAAACCAAAAAATGAACCCCTTGTGTCGTTGTTAACCCATCCTTTCATTTACTCA
TATAATTAGCCAAAAAAAAAAGGATGGCTACATACCAATGGATTGATTCTCTTAATTGCCACGGCAAGGGGGCGATCCTATCATGACTTA
ACATCAAGCGCGCAGTTCAAAACTACTGTCTTCTGTCAAAGTTTTCTCCTCTTAAATGTTATTTTGCTTTTACGTCTCAACTGTGTATGT
AAAAAAAATGAATATTTAAATTACAACCCTAGACTAAAAATGTGTTTATAATAAGATGTGGATATTTCCTTCAGTAGATTGTAACCATAA
TTTAAATTATTTTGTTCCACACTGTTTTTTATATCTGTCATGTACATTGCATTTTGATCTGTAACTGCACAACCCTGGGGTTTGCTGCAG
AGCTATTTCTTTCCATGTAAAGTAGTGGATCCATCTTGCTTTTGCCTTATATAAAGCCTACAGTTATGGAAGTGTGGAAAACTGTGGCTT
CTCAATAAATATTCAGATGTCCTAAGAATAT

>14412_14412_3_CD22-CADPS_CD22_chr19_35823827_ENST00000419549_CADPS_chr3_62751659_ENST00000383710_length(amino acids)=1219AA_BP=13
MRNGWNEYTSMSLISKQQLQTVKDRFQAFLNGETQIMADEAFMNAVQSYYEVFLKSDRVARMVQSGGCSANDSREVFKKHIEKRVRSLPE
IDGLSKETVLSSWMAKFDAIYRGEEDPRKQQARMTASAASELILSKEQLYEMFQNILGIKKFEHQLLYNACQLDNPDEQAAQIRRELDGR
LQMADQIARERKFPKFVSKEMENMYIEELKSSVNLLMANLESMPVSKGGEFKLQKLKRSHNASIIDMGEESENQLSKSDVVLSFSLEVVI
MEVQGLKSLAPNRIVYCTMEVEGGEKLQTDQAEASKPTWGTQGDFSTTHALPAVKVKLFTESTGVLALEDKELGRVILHPTPNSPKQSEW
HKMTVSKNCPDQDLKIKLAVRMDKPQNMKHSGYLWAIGKNVWKRWKKRFFVLVQVSQYTFAMCSYREKKAEPQELLQLDGYTVDYTDPQP
GLEGGRAFFNAVKEGDTVIFASDDEQDRILWVQAMYRATGQSHKPVPPTQVQKLNAKGGNVPQLDAPISQFYADRAQKHGMDEFISSNPC
NFDHASLFEMVQRLTLDHRLNDSYSCLGWFSPGQVFVLDEYCARNGVRGCHRHLCYLRDLLERAENGAMIDPTLLHYSFAFCASHVHGNR
PDGIGTVTVEEKERFEEIKERLRVLLENQITHFRYCFPFGRPEGALKATLSLLERVLMKDIVTPVPQEEVKTVIRKCLEQAALVNYSRLS
EYAKIEENQKDAENVGRLITPAKKLEDTIRLAELVIEVLQQNEEHHAEPHVDKGEAFAWWSDLMVEHAETFLSLFAVDMDAALEVQPPDT
WDSFPLFQLLNDFLRTDYNLCNGKFHKHLQDLFAPLVVRYVDLMESSIAQSIHRGFERESWEPVKSLTSNLPNVNLPNVNLPKVPNLPVN
IPLGIPQMPTFSAPSWMAAIYDADNGSGTSEDLFWKLDALQTFIRDLHWPEEEFGKHLEQRLKLMASDMIESCVKRTRIAFEVKLQKTSR
STDFRVPQSICTMFNVMVDAKAQSTKLCSMEMGQEHQYHSKIDELIEETVKEMITLLVAKFVTILEGVLAKLSRYDEGTLFSSFLSFTVK
AASKYVDVPKPGMDVADAYVTFVRHSQDVLRDKVNEEMYIERLFDQWYNSSMNVICTWLTDRMDLQLHIYQLKTLIRMVKKTYRDFRLQG
VLDSTLNSKTYETIRNRLTVEEATASVSEGGGLQGISMKDSDEEDEEDD

--------------------------------------------------------------
>14412_14412_4_CD22-CADPS_CD22_chr19_35823827_ENST00000419549_CADPS_chr3_62751659_ENST00000490353_length(transcript)=2619nt_BP=391nt
GGAAGACACGCGGAAACAGAATACTTGGCTTTCTCTGACTCAAGTAAATGGGTTTTTGAGCACCCTGAAACCCTCTACGCCTGGGAGGGG
GCCTGCGTCTGGATCCCCTGCACCTACAGAGCCCTAGATGGTGACCTGGAAAGCTTCATCCTGTTCCACAATCCTGAGTATAACAAGAAC
ACCTCGAAGTTTGATGGGACAAGACTCTATGAAAGCACAAAGGATGGGAAGGTTCCTTCTGAGCAGAAAAGGGTGCAATTCCTGGGAGAC
AAGAATAAGAACTGCACACTGAGTATCCACCCGGTGCACCTCAATGACAGTGGTCAGCTGGGGCTGAGGATGGAGTCCAAGACTGAGAAA
TGGATGGAACGAATACACCTCAATGTCTCTGATCAGCAAACAGCAGCTGCAGACAGTCAAGGACCGGTTTCAGGCTTTCCTCAATGGGGA
AACCCAGATCATGGCTGACGAAGCCTTCATGAACGCTGTGCAGAGTTACTATGAGGTGTTCCTGAAGAGCGACCGTGTGGCCCGCATGGT
TCAGAGTGGAGGCTGTTCCGCCAACGACTCCCGGGAGGTCTTCAAGAAGCACATTGAGAAGAGAGTGCGCAGCCTGCCTGAGATTGACGG
CCTCAGCAAGGAGACTGTGCTGAGCTCCTGGATGGCCAAATTTGATGCCATCTACCGTGGAGAAGAGGACCCGCGGAAGCAGCAGGCCCG
GATGACAGCCAGCGCAGCCTCCGAGCTGATTCTGAGCAAGGAGCAACTCTATGAGATGTTCCAGAACATTCTTGGGATCAAGAAGTTCGA
ACATCAGCTCCTTTACAATGCCTGCCAGCTGGACAATCCAGATGAGCAAGCAGCCCAGATCAGACGAGAGCTGGATGGACGTCTACAAAT
GGCAGACCAAATAGCCAGGGAACGCAAATTTCCCAAGTTTGTATCCAAAGAAATGGAAAACATGTACATTGAGGAGCTGAAGTCATCTGT
CAACCTGCTCATGGCCAACTTGGAGAGCATGCCGGTATCCAAAGGCGGGGAGTTCAAGCTCCAGAAACTCAAACGCAGCCACAATGCTTC
CATCATCGACATGGGCGAGGAGAGTGAGAACCAGCTCTCCAAGTCAGATGTCGTGCTGTCTTTCTCATTGGAGGTGGTAATTATGGAAGT
CCAAGGCCTCAAATCTTTGGCTCCAAATCGCATCGTATATTGCACAATGGAGGTGGAAGGAGGAGAGAAACTACAGACTGATCAGGCCGA
GGCTTCTAAACCAACGGTAATCAGGAGAAACAGAAGAGAACAACTGCCTCACAGTGCCATTTGATGTCCCGTCTTTGTGCCATGTCAAAT
CATCTCCAGGGGTACAAGATTTGTGCTTGAAGAGTCACAGTACCCAATCTCTGTTTACTGAATAATTTCACTATAGTCTGTGTATTTCCC
TGGTTTACACTCATCCTTTTGGGTGTTTTTCCTAGAGCATTCCATGGTTTCTTTTCTGTTTAGTAAATCCGTGCCAGCTTGCAAAGTGAC
GTGAATGAGAAAGATGGAATTAGTAATGTTGTTGAATGTGAACACTCAAGACAAAAGAAAGAAAACATTTTCCCCCTTAGCTGGCTTTGT
CTTCTCAATGACCGGAATGAAATGTCAAGTGAACGTGTTAATTCTTAATGGGGATACCAATGAAAGCTTCAGGGGAAGAGAACATTTAAC
AGAGGCTCTCACTTTTCTCTGAATTTTATTTGGATAGACATTAGCATTTTATTACAGCCTTGGAAAAGATGAGATGACAATTATTGACAA
GGTTCCCAGGACACAAATAAATAAAATGAATAAATTGTTTATTTGATAAATTTCAATTATCTACAAGGTGTAAAACACTATAGATGCGAA
TGATTAAAAAATAAAGAGCAAAGACCCTGTTTTCAGGATGCAGCATACTTACAGGGAAATAAATCATGTACATTTAGTAGTGAATATAAA
AAAGTAAAGATTCCATTCTGGGGAAAACTGCAGATTGCTTCTGTTGAGAAAACCAAAGAATGGTCCTGGAGAAGATGGCTCTTGAAAATG
GCCCTTGAATTTGGCTAGAAAGCATTTGCAAGTACAGAAAGGGTGGCAAGGGCATTCCAGCAAAACGAAGTGGTATCCGCCAACACCTAT
AGTCTCAGAAGTGCTGTACTGTGTAGGGAACGTAGGTTCTAAAAAGGAGGTATAAAAGGAGGAAGAGAAAAGAAAGAAATCTATAAATAT
AGGCTGAGTCAAGGTATAAAAGAGCTTTGCGGACGAAACTAAGAGGAAGAGAGCTTAAAGAAACAAGTACATTTAGCAGGGATAGGATAA
ACACTGGGGACAGAGAGCTCCTGAACCAGTGTGACCCGGCTCCAGTGGTGTCCTGTTTCTGTGCCTCTCCATTCATGTGAACATGTGTGT
GCATGTGTGTGCGTGTGTGTGTGTGTGTGTGTGTGTGAAAAACTTTTATGACAAAATTGAAATGACATTGTTAGTCATACATTTTGACAT
TGAATTTTACAATGTTTATGCATCTAAGCTTGCAGCCGTTATACTTGGATAATCTATGTCTTTGTTTCTGCTATAAAACCATGTTTTCTC
TTGGTGTGG

>14412_14412_4_CD22-CADPS_CD22_chr19_35823827_ENST00000419549_CADPS_chr3_62751659_ENST00000490353_length(amino acids)=323AA_BP=13
MRNGWNEYTSMSLISKQQLQTVKDRFQAFLNGETQIMADEAFMNAVQSYYEVFLKSDRVARMVQSGGCSANDSREVFKKHIEKRVRSLPE
IDGLSKETVLSSWMAKFDAIYRGEEDPRKQQARMTASAASELILSKEQLYEMFQNILGIKKFEHQLLYNACQLDNPDEQAAQIRRELDGR
LQMADQIARERKFPKFVSKEMENMYIEELKSSVNLLMANLESMPVSKGGEFKLQKLKRSHNASIIDMGEESENQLSKSDVVLSFSLEVVI
MEVQGLKSLAPNRIVYCTMEVEGGEKLQTDQAEASKPTVIRRNRREQLPHSAI

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Fusion Gene PPI Analysis for CD22-CADPS


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
TgeneCADPSchr19:35823827chr3:62751659ENST00000283269028790_1129147.01315.0DRD2
TgeneCADPSchr19:35823827chr3:62751659ENST00000357948027790_1129147.01275.0DRD2
TgeneCADPSchr19:35823827chr3:62751659ENST00000383710030790_1129147.01354.0DRD2
TgeneCADPSchr19:35823827chr3:62751659ENST0000049035307790_1129147.0458.0DRD2


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for CD22-CADPS


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for CD22-CADPS


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource