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Fusion Gene Summary | |
Fusion Gene ORF analysis | |
Fusion Genomic Features | |
Fusion Protein Features | |
Fusion Gene Sequence | |
Fusion Gene PPI analysis | |
Related Drugs | |
Related Diseases |
Fusion gene:AKAP7-ESR1 (FusionGDB2 ID:HG9465TG2099) |
Fusion Gene Summary for AKAP7-ESR1 |
Fusion gene summary |
Fusion gene information | Fusion gene name: AKAP7-ESR1 | Fusion gene ID: hg9465tg2099 | Hgene | Tgene | Gene symbol | AKAP7 | ESR1 | Gene ID | 9465 | 2099 |
Gene name | A-kinase anchoring protein 7 | estrogen receptor 1 | |
Synonyms | AKAP15|AKAP18 | ER|ESR|ESRA|ESTRR|Era|NR3A1 | |
Cytomap | ('AKAP7')('ESR1') 6q23.2 | 6q25.1-q25.2 | |
Type of gene | protein-coding | protein-coding | |
Description | A-kinase anchoring protein 7A kinase (PRKA) anchor protein 7A-kinase anchor protein 18 kDaA-kinase anchor protein 9 kDaAKAP 18 | estrogen receptorE2 receptor alphaER-alphaestradiol receptorestrogen nuclear receptor alphaestrogen receptor alpha E1-E2-1-2estrogen receptor alpha E1-N2-E2-1-2nuclear receptor subfamily 3 group A member 1oestrogen receptor alpha | |
Modification date | 20200313 | 20200329 | |
UniProtAcc | . | . | |
Ensembl transtripts involved in fusion gene | ENST00000366358, ENST00000368123, ENST00000431975, ENST00000541650, ENST00000263050, ENST00000342266, ENST00000474850, ENST00000537868, | ||
Fusion gene scores | * DoF score | 6 X 3 X 6=108 | 10 X 10 X 6=600 |
# samples | 7 | 12 | |
** MAII score | log2(7/108*10)=-0.625604485218502 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(12/600*10)=-2.32192809488736 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
Context | PubMed: AKAP7 [Title/Abstract] AND ESR1 [Title/Abstract] AND fusion [Title/Abstract] | ||
Most frequent breakpoint | AKAP7(131466556)-ESR1(152415520), # samples:2 | ||
Anticipated loss of major functional domain due to fusion event. | AKAP7-ESR1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. AKAP7-ESR1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. AKAP7-ESR1 seems lost the major protein functional domain in Tgene partner, which is a CGC due to the frame-shifted ORF. AKAP7-ESR1 seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF. AKAP7-ESR1 seems lost the major protein functional domain in Tgene partner, which is a transcription factor due to the frame-shifted ORF. AKAP7-ESR1 seems lost the major protein functional domain in Tgene partner, which is a tumor suppressor due to the frame-shifted ORF. |
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
Partner | Gene | GO ID | GO term | PubMed ID |
Tgene | ESR1 | GO:0006366 | transcription by RNA polymerase II | 15831516 |
Tgene | ESR1 | GO:0010629 | negative regulation of gene expression | 21695196 |
Tgene | ESR1 | GO:0030520 | intracellular estrogen receptor signaling pathway | 9841876 |
Tgene | ESR1 | GO:0032355 | response to estradiol | 15304487 |
Tgene | ESR1 | GO:0043124 | negative regulation of I-kappaB kinase/NF-kappaB signaling | 7651415|16043358 |
Tgene | ESR1 | GO:0043433 | negative regulation of DNA-binding transcription factor activity | 10816575 |
Tgene | ESR1 | GO:0043627 | response to estrogen | 11581164 |
Tgene | ESR1 | GO:0045893 | positive regulation of transcription, DNA-templated | 9841876|20074560 |
Tgene | ESR1 | GO:0045899 | positive regulation of RNA polymerase II transcriptional preinitiation complex assembly | 9841876 |
Tgene | ESR1 | GO:0045944 | positive regulation of transcription by RNA polymerase II | 11544182|12047722|15345745|15831516|18563714 |
Tgene | ESR1 | GO:0051091 | positive regulation of DNA-binding transcription factor activity | 9328340|10681512 |
Tgene | ESR1 | GO:0071392 | cellular response to estradiol stimulus | 15831516 |
Fusion gene breakpoints across AKAP7 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
Fusion gene breakpoints across ESR1 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
ChimerDB4 | BRCA | TCGA-A8-A08I-01A | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + |
ChimerDB4 | BRCA | TCGA-A8-A08I-01A | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419867 | + |
ChimerDB4 | BRCA | TCGA-A8-A08I | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419866 | + |
Top |
Fusion Gene ORF analysis for AKAP7-ESR1 |
Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
3UTR-3CDS | ENST00000366358 | ENST00000206249 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + |
3UTR-3CDS | ENST00000366358 | ENST00000206249 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419867 | + |
3UTR-3CDS | ENST00000366358 | ENST00000206249 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419866 | + |
3UTR-3CDS | ENST00000366358 | ENST00000338799 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + |
3UTR-3CDS | ENST00000366358 | ENST00000338799 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419867 | + |
3UTR-3CDS | ENST00000366358 | ENST00000338799 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419866 | + |
3UTR-3CDS | ENST00000366358 | ENST00000406599 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + |
3UTR-3CDS | ENST00000366358 | ENST00000406599 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419867 | + |
3UTR-3CDS | ENST00000366358 | ENST00000406599 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419866 | + |
3UTR-3CDS | ENST00000366358 | ENST00000440973 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + |
3UTR-3CDS | ENST00000366358 | ENST00000440973 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419867 | + |
3UTR-3CDS | ENST00000366358 | ENST00000440973 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419866 | + |
3UTR-3CDS | ENST00000366358 | ENST00000443427 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + |
3UTR-3CDS | ENST00000366358 | ENST00000443427 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419867 | + |
3UTR-3CDS | ENST00000366358 | ENST00000443427 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419866 | + |
3UTR-3CDS | ENST00000366358 | ENST00000456483 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + |
3UTR-3CDS | ENST00000366358 | ENST00000456483 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419867 | + |
3UTR-3CDS | ENST00000366358 | ENST00000456483 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419866 | + |
3UTR-intron | ENST00000366358 | ENST00000427531 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + |
3UTR-intron | ENST00000366358 | ENST00000427531 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419867 | + |
3UTR-intron | ENST00000366358 | ENST00000427531 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419866 | + |
3UTR-intron | ENST00000366358 | ENST00000482101 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + |
3UTR-intron | ENST00000366358 | ENST00000482101 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419867 | + |
3UTR-intron | ENST00000366358 | ENST00000482101 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419866 | + |
5CDS-intron | ENST00000368123 | ENST00000427531 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + |
5CDS-intron | ENST00000368123 | ENST00000427531 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419867 | + |
5CDS-intron | ENST00000368123 | ENST00000427531 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419866 | + |
5CDS-intron | ENST00000368123 | ENST00000482101 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + |
5CDS-intron | ENST00000368123 | ENST00000482101 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419867 | + |
5CDS-intron | ENST00000368123 | ENST00000482101 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419866 | + |
5CDS-intron | ENST00000431975 | ENST00000427531 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + |
5CDS-intron | ENST00000431975 | ENST00000427531 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419867 | + |
5CDS-intron | ENST00000431975 | ENST00000427531 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419866 | + |
5CDS-intron | ENST00000431975 | ENST00000482101 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + |
5CDS-intron | ENST00000431975 | ENST00000482101 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419867 | + |
5CDS-intron | ENST00000431975 | ENST00000482101 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419866 | + |
5CDS-intron | ENST00000541650 | ENST00000427531 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + |
5CDS-intron | ENST00000541650 | ENST00000427531 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419867 | + |
5CDS-intron | ENST00000541650 | ENST00000427531 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419866 | + |
5CDS-intron | ENST00000541650 | ENST00000482101 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + |
5CDS-intron | ENST00000541650 | ENST00000482101 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419867 | + |
5CDS-intron | ENST00000541650 | ENST00000482101 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419866 | + |
Frame-shift | ENST00000368123 | ENST00000206249 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419867 | + |
Frame-shift | ENST00000368123 | ENST00000206249 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419866 | + |
Frame-shift | ENST00000368123 | ENST00000338799 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419867 | + |
Frame-shift | ENST00000368123 | ENST00000338799 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419866 | + |
Frame-shift | ENST00000368123 | ENST00000406599 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419867 | + |
Frame-shift | ENST00000368123 | ENST00000406599 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419866 | + |
Frame-shift | ENST00000368123 | ENST00000440973 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419867 | + |
Frame-shift | ENST00000368123 | ENST00000440973 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419866 | + |
Frame-shift | ENST00000368123 | ENST00000443427 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419867 | + |
Frame-shift | ENST00000368123 | ENST00000443427 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419866 | + |
Frame-shift | ENST00000368123 | ENST00000456483 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419867 | + |
Frame-shift | ENST00000368123 | ENST00000456483 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419866 | + |
Frame-shift | ENST00000431975 | ENST00000206249 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419867 | + |
Frame-shift | ENST00000431975 | ENST00000206249 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419866 | + |
Frame-shift | ENST00000431975 | ENST00000338799 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419867 | + |
Frame-shift | ENST00000431975 | ENST00000338799 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419866 | + |
Frame-shift | ENST00000431975 | ENST00000406599 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419867 | + |
Frame-shift | ENST00000431975 | ENST00000406599 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419866 | + |
Frame-shift | ENST00000431975 | ENST00000440973 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419867 | + |
Frame-shift | ENST00000431975 | ENST00000440973 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419866 | + |
Frame-shift | ENST00000431975 | ENST00000443427 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419867 | + |
Frame-shift | ENST00000431975 | ENST00000443427 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419866 | + |
Frame-shift | ENST00000431975 | ENST00000456483 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419867 | + |
Frame-shift | ENST00000431975 | ENST00000456483 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419866 | + |
Frame-shift | ENST00000541650 | ENST00000206249 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419867 | + |
Frame-shift | ENST00000541650 | ENST00000206249 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419866 | + |
Frame-shift | ENST00000541650 | ENST00000338799 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419867 | + |
Frame-shift | ENST00000541650 | ENST00000338799 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419866 | + |
Frame-shift | ENST00000541650 | ENST00000406599 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419867 | + |
Frame-shift | ENST00000541650 | ENST00000406599 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419866 | + |
Frame-shift | ENST00000541650 | ENST00000440973 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419867 | + |
Frame-shift | ENST00000541650 | ENST00000440973 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419866 | + |
Frame-shift | ENST00000541650 | ENST00000443427 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419867 | + |
Frame-shift | ENST00000541650 | ENST00000443427 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419866 | + |
Frame-shift | ENST00000541650 | ENST00000456483 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419867 | + |
Frame-shift | ENST00000541650 | ENST00000456483 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419866 | + |
In-frame | ENST00000368123 | ENST00000206249 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + |
In-frame | ENST00000368123 | ENST00000338799 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + |
In-frame | ENST00000368123 | ENST00000406599 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + |
In-frame | ENST00000368123 | ENST00000440973 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + |
In-frame | ENST00000368123 | ENST00000443427 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + |
In-frame | ENST00000368123 | ENST00000456483 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + |
In-frame | ENST00000431975 | ENST00000206249 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + |
In-frame | ENST00000431975 | ENST00000338799 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + |
In-frame | ENST00000431975 | ENST00000406599 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + |
In-frame | ENST00000431975 | ENST00000440973 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + |
In-frame | ENST00000431975 | ENST00000443427 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + |
In-frame | ENST00000431975 | ENST00000456483 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + |
In-frame | ENST00000541650 | ENST00000206249 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + |
In-frame | ENST00000541650 | ENST00000338799 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + |
In-frame | ENST00000541650 | ENST00000406599 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + |
In-frame | ENST00000541650 | ENST00000440973 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + |
In-frame | ENST00000541650 | ENST00000443427 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + |
In-frame | ENST00000541650 | ENST00000456483 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + |
intron-3CDS | ENST00000263050 | ENST00000206249 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + |
intron-3CDS | ENST00000263050 | ENST00000206249 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419867 | + |
intron-3CDS | ENST00000263050 | ENST00000206249 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419866 | + |
intron-3CDS | ENST00000263050 | ENST00000338799 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + |
intron-3CDS | ENST00000263050 | ENST00000338799 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419867 | + |
intron-3CDS | ENST00000263050 | ENST00000338799 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419866 | + |
intron-3CDS | ENST00000263050 | ENST00000406599 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + |
intron-3CDS | ENST00000263050 | ENST00000406599 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419867 | + |
intron-3CDS | ENST00000263050 | ENST00000406599 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419866 | + |
intron-3CDS | ENST00000263050 | ENST00000440973 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + |
intron-3CDS | ENST00000263050 | ENST00000440973 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419867 | + |
intron-3CDS | ENST00000263050 | ENST00000440973 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419866 | + |
intron-3CDS | ENST00000263050 | ENST00000443427 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + |
intron-3CDS | ENST00000263050 | ENST00000443427 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419867 | + |
intron-3CDS | ENST00000263050 | ENST00000443427 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419866 | + |
intron-3CDS | ENST00000263050 | ENST00000456483 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + |
intron-3CDS | ENST00000263050 | ENST00000456483 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419867 | + |
intron-3CDS | ENST00000263050 | ENST00000456483 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419866 | + |
intron-3CDS | ENST00000342266 | ENST00000206249 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + |
intron-3CDS | ENST00000342266 | ENST00000206249 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419867 | + |
intron-3CDS | ENST00000342266 | ENST00000206249 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419866 | + |
intron-3CDS | ENST00000342266 | ENST00000338799 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + |
intron-3CDS | ENST00000342266 | ENST00000338799 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419867 | + |
intron-3CDS | ENST00000342266 | ENST00000338799 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419866 | + |
intron-3CDS | ENST00000342266 | ENST00000406599 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + |
intron-3CDS | ENST00000342266 | ENST00000406599 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419867 | + |
intron-3CDS | ENST00000342266 | ENST00000406599 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419866 | + |
intron-3CDS | ENST00000342266 | ENST00000440973 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + |
intron-3CDS | ENST00000342266 | ENST00000440973 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419867 | + |
intron-3CDS | ENST00000342266 | ENST00000440973 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419866 | + |
intron-3CDS | ENST00000342266 | ENST00000443427 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + |
intron-3CDS | ENST00000342266 | ENST00000443427 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419867 | + |
intron-3CDS | ENST00000342266 | ENST00000443427 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419866 | + |
intron-3CDS | ENST00000342266 | ENST00000456483 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + |
intron-3CDS | ENST00000342266 | ENST00000456483 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419867 | + |
intron-3CDS | ENST00000342266 | ENST00000456483 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419866 | + |
intron-3CDS | ENST00000474850 | ENST00000206249 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + |
intron-3CDS | ENST00000474850 | ENST00000206249 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419867 | + |
intron-3CDS | ENST00000474850 | ENST00000206249 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419866 | + |
intron-3CDS | ENST00000474850 | ENST00000338799 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + |
intron-3CDS | ENST00000474850 | ENST00000338799 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419867 | + |
intron-3CDS | ENST00000474850 | ENST00000338799 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419866 | + |
intron-3CDS | ENST00000474850 | ENST00000406599 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + |
intron-3CDS | ENST00000474850 | ENST00000406599 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419867 | + |
intron-3CDS | ENST00000474850 | ENST00000406599 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419866 | + |
intron-3CDS | ENST00000474850 | ENST00000440973 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + |
intron-3CDS | ENST00000474850 | ENST00000440973 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419867 | + |
intron-3CDS | ENST00000474850 | ENST00000440973 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419866 | + |
intron-3CDS | ENST00000474850 | ENST00000443427 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + |
intron-3CDS | ENST00000474850 | ENST00000443427 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419867 | + |
intron-3CDS | ENST00000474850 | ENST00000443427 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419866 | + |
intron-3CDS | ENST00000474850 | ENST00000456483 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + |
intron-3CDS | ENST00000474850 | ENST00000456483 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419867 | + |
intron-3CDS | ENST00000474850 | ENST00000456483 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419866 | + |
intron-3CDS | ENST00000537868 | ENST00000206249 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + |
intron-3CDS | ENST00000537868 | ENST00000206249 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419867 | + |
intron-3CDS | ENST00000537868 | ENST00000206249 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419866 | + |
intron-3CDS | ENST00000537868 | ENST00000338799 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + |
intron-3CDS | ENST00000537868 | ENST00000338799 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419867 | + |
intron-3CDS | ENST00000537868 | ENST00000338799 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419866 | + |
intron-3CDS | ENST00000537868 | ENST00000406599 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + |
intron-3CDS | ENST00000537868 | ENST00000406599 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419867 | + |
intron-3CDS | ENST00000537868 | ENST00000406599 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419866 | + |
intron-3CDS | ENST00000537868 | ENST00000440973 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + |
intron-3CDS | ENST00000537868 | ENST00000440973 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419867 | + |
intron-3CDS | ENST00000537868 | ENST00000440973 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419866 | + |
intron-3CDS | ENST00000537868 | ENST00000443427 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + |
intron-3CDS | ENST00000537868 | ENST00000443427 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419867 | + |
intron-3CDS | ENST00000537868 | ENST00000443427 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419866 | + |
intron-3CDS | ENST00000537868 | ENST00000456483 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + |
intron-3CDS | ENST00000537868 | ENST00000456483 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419867 | + |
intron-3CDS | ENST00000537868 | ENST00000456483 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419866 | + |
intron-intron | ENST00000263050 | ENST00000427531 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + |
intron-intron | ENST00000263050 | ENST00000427531 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419867 | + |
intron-intron | ENST00000263050 | ENST00000427531 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419866 | + |
intron-intron | ENST00000263050 | ENST00000482101 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + |
intron-intron | ENST00000263050 | ENST00000482101 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419867 | + |
intron-intron | ENST00000263050 | ENST00000482101 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419866 | + |
intron-intron | ENST00000342266 | ENST00000427531 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + |
intron-intron | ENST00000342266 | ENST00000427531 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419867 | + |
intron-intron | ENST00000342266 | ENST00000427531 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419866 | + |
intron-intron | ENST00000342266 | ENST00000482101 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + |
intron-intron | ENST00000342266 | ENST00000482101 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419867 | + |
intron-intron | ENST00000342266 | ENST00000482101 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419866 | + |
intron-intron | ENST00000474850 | ENST00000427531 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + |
intron-intron | ENST00000474850 | ENST00000427531 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419867 | + |
intron-intron | ENST00000474850 | ENST00000427531 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419866 | + |
intron-intron | ENST00000474850 | ENST00000482101 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + |
intron-intron | ENST00000474850 | ENST00000482101 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419867 | + |
intron-intron | ENST00000474850 | ENST00000482101 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419866 | + |
intron-intron | ENST00000537868 | ENST00000427531 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + |
intron-intron | ENST00000537868 | ENST00000427531 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419867 | + |
intron-intron | ENST00000537868 | ENST00000427531 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419866 | + |
intron-intron | ENST00000537868 | ENST00000482101 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + |
intron-intron | ENST00000537868 | ENST00000482101 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419867 | + |
intron-intron | ENST00000537868 | ENST00000482101 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419866 | + |
ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
ENST00000431975 | AKAP7 | chr6 | 131466556 | + | ENST00000440973 | ESR1 | chr6 | 152415520 | + | 4976 | 249 | 98 | 667 | 189 |
ENST00000431975 | AKAP7 | chr6 | 131466556 | + | ENST00000338799 | ESR1 | chr6 | 152415520 | + | 755 | 249 | 98 | 667 | 189 |
ENST00000431975 | AKAP7 | chr6 | 131466556 | + | ENST00000456483 | ESR1 | chr6 | 152415520 | + | 4976 | 249 | 98 | 667 | 189 |
ENST00000431975 | AKAP7 | chr6 | 131466556 | + | ENST00000443427 | ESR1 | chr6 | 152415520 | + | 4976 | 249 | 98 | 667 | 189 |
ENST00000431975 | AKAP7 | chr6 | 131466556 | + | ENST00000206249 | ESR1 | chr6 | 152415520 | + | 4973 | 249 | 98 | 667 | 189 |
ENST00000431975 | AKAP7 | chr6 | 131466556 | + | ENST00000406599 | ESR1 | chr6 | 152415520 | + | 680 | 249 | 98 | 667 | 189 |
ENST00000541650 | AKAP7 | chr6 | 131466556 | + | ENST00000440973 | ESR1 | chr6 | 152415520 | + | 4902 | 175 | 27 | 593 | 188 |
ENST00000541650 | AKAP7 | chr6 | 131466556 | + | ENST00000338799 | ESR1 | chr6 | 152415520 | + | 681 | 175 | 27 | 593 | 188 |
ENST00000541650 | AKAP7 | chr6 | 131466556 | + | ENST00000456483 | ESR1 | chr6 | 152415520 | + | 4902 | 175 | 27 | 593 | 188 |
ENST00000541650 | AKAP7 | chr6 | 131466556 | + | ENST00000443427 | ESR1 | chr6 | 152415520 | + | 4902 | 175 | 27 | 593 | 188 |
ENST00000541650 | AKAP7 | chr6 | 131466556 | + | ENST00000206249 | ESR1 | chr6 | 152415520 | + | 4899 | 175 | 27 | 593 | 188 |
ENST00000541650 | AKAP7 | chr6 | 131466556 | + | ENST00000406599 | ESR1 | chr6 | 152415520 | + | 606 | 175 | 27 | 593 | 188 |
ENST00000368123 | AKAP7 | chr6 | 131466556 | + | ENST00000440973 | ESR1 | chr6 | 152415520 | + | 4823 | 96 | 11 | 514 | 167 |
ENST00000368123 | AKAP7 | chr6 | 131466556 | + | ENST00000338799 | ESR1 | chr6 | 152415520 | + | 602 | 96 | 11 | 514 | 167 |
ENST00000368123 | AKAP7 | chr6 | 131466556 | + | ENST00000456483 | ESR1 | chr6 | 152415520 | + | 4823 | 96 | 11 | 514 | 167 |
ENST00000368123 | AKAP7 | chr6 | 131466556 | + | ENST00000443427 | ESR1 | chr6 | 152415520 | + | 4823 | 96 | 11 | 514 | 167 |
ENST00000368123 | AKAP7 | chr6 | 131466556 | + | ENST00000206249 | ESR1 | chr6 | 152415520 | + | 4820 | 96 | 11 | 514 | 167 |
ENST00000368123 | AKAP7 | chr6 | 131466556 | + | ENST00000406599 | ESR1 | chr6 | 152415520 | + | 527 | 96 | 11 | 514 | 167 |
DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
ENST00000431975 | ENST00000440973 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + | 0.002212181 | 0.99778783 |
ENST00000431975 | ENST00000338799 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + | 0.000478852 | 0.99952114 |
ENST00000431975 | ENST00000456483 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + | 0.002212181 | 0.99778783 |
ENST00000431975 | ENST00000443427 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + | 0.002212181 | 0.99778783 |
ENST00000431975 | ENST00000206249 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + | 0.002506949 | 0.997493 |
ENST00000431975 | ENST00000406599 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + | 0.00039471 | 0.99960536 |
ENST00000541650 | ENST00000440973 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + | 0.001961615 | 0.99803835 |
ENST00000541650 | ENST00000338799 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + | 0.000406991 | 0.9995931 |
ENST00000541650 | ENST00000456483 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + | 0.001961615 | 0.99803835 |
ENST00000541650 | ENST00000443427 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + | 0.001961615 | 0.99803835 |
ENST00000541650 | ENST00000206249 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + | 0.002226753 | 0.99777323 |
ENST00000541650 | ENST00000406599 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + | 0.000314723 | 0.9996853 |
ENST00000368123 | ENST00000440973 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + | 0.003325003 | 0.996675 |
ENST00000368123 | ENST00000338799 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + | 0.000439292 | 0.99956065 |
ENST00000368123 | ENST00000456483 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + | 0.003325003 | 0.996675 |
ENST00000368123 | ENST00000443427 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + | 0.003325003 | 0.996675 |
ENST00000368123 | ENST00000206249 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + | 0.003933732 | 0.9960663 |
ENST00000368123 | ENST00000406599 | AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415520 | + | 0.000416133 | 0.9995839 |
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Fusion Genomic Features for AKAP7-ESR1 |
FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419866 | + | 1.96E-05 | 0.99998033 |
AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419866 | + | 1.96E-05 | 0.99998033 |
AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415519 | + | 3.62E-09 | 1 |
AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419866 | + | 1.96E-05 | 0.99998033 |
AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152419866 | + | 1.96E-05 | 0.99998033 |
AKAP7 | chr6 | 131466556 | + | ESR1 | chr6 | 152415519 | + | 3.62E-09 | 1 |
Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for AKAP7-ESR1 |
Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr6:131466556/chr6:152415520) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
Main function of each fusion partner protein. (from UniProt) |
Hgene | Tgene |
. | . |
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. | FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. |
Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
- In-frame and retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
- In-frame and not-retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
Hgene | AKAP7 | chr6:131466556 | chr6:152415520 | ENST00000368123 | + | 1 | 7 | 219_221 | 28 | 327.0 | Nucleotide binding | CMP |
Hgene | AKAP7 | chr6:131466556 | chr6:152415520 | ENST00000431975 | + | 2 | 8 | 219_221 | 50 | 349.0 | Nucleotide binding | CMP |
Hgene | AKAP7 | chr6:131466556 | chr6:152415520 | ENST00000342266 | + | 1 | 2 | 2_11 | 0 | 82.0 | Region | Note=Required for membrane localization |
Hgene | AKAP7 | chr6:131466556 | chr6:152415520 | ENST00000342266 | + | 1 | 2 | 52_65 | 0 | 82.0 | Region | Note=RII-binding |
Hgene | AKAP7 | chr6:131466556 | chr6:152415520 | ENST00000368123 | + | 1 | 7 | 294_348 | 28 | 327.0 | Region | PKA-RII-alpha subunit binding domain |
Hgene | AKAP7 | chr6:131466556 | chr6:152415520 | ENST00000368123 | + | 1 | 7 | 295_319 | 28 | 327.0 | Region | RI-alpha-binding |
Hgene | AKAP7 | chr6:131466556 | chr6:152415520 | ENST00000368123 | + | 1 | 7 | 296_309 | 28 | 327.0 | Region | Note=RII-binding |
Hgene | AKAP7 | chr6:131466556 | chr6:152415520 | ENST00000431975 | + | 2 | 8 | 294_348 | 50 | 349.0 | Region | PKA-RII-alpha subunit binding domain |
Hgene | AKAP7 | chr6:131466556 | chr6:152415520 | ENST00000431975 | + | 2 | 8 | 295_319 | 50 | 349.0 | Region | RI-alpha-binding |
Hgene | AKAP7 | chr6:131466556 | chr6:152415520 | ENST00000431975 | + | 2 | 8 | 296_309 | 50 | 349.0 | Region | Note=RII-binding |
Hgene | AKAP7 | chr6:131466556 | chr6:152415520 | ENST00000474850 | + | 1 | 3 | 2_11 | 0 | 105.0 | Region | Note=Required for membrane localization |
Hgene | AKAP7 | chr6:131466556 | chr6:152415520 | ENST00000474850 | + | 1 | 3 | 52_65 | 0 | 105.0 | Region | Note=RII-binding |
Tgene | ESR1 | chr6:131466556 | chr6:152415520 | ENST00000206249 | 5 | 8 | 185_250 | 456 | 596.0 | DNA binding | Nuclear receptor | |
Tgene | ESR1 | chr6:131466556 | chr6:152415520 | ENST00000338799 | 6 | 9 | 185_250 | 456 | 596.0 | DNA binding | Nuclear receptor | |
Tgene | ESR1 | chr6:131466556 | chr6:152415520 | ENST00000440973 | 7 | 10 | 185_250 | 456 | 596.0 | DNA binding | Nuclear receptor | |
Tgene | ESR1 | chr6:131466556 | chr6:152415520 | ENST00000443427 | 6 | 9 | 185_250 | 456 | 596.0 | DNA binding | Nuclear receptor | |
Tgene | ESR1 | chr6:131466556 | chr6:152415520 | ENST00000456483 | 5 | 8 | 185_250 | 344 | 484.0 | DNA binding | Nuclear receptor | |
Tgene | ESR1 | chr6:131466556 | chr6:152415520 | ENST00000206249 | 5 | 8 | 311_547 | 456 | 596.0 | Domain | NR LBD | |
Tgene | ESR1 | chr6:131466556 | chr6:152415520 | ENST00000338799 | 6 | 9 | 311_547 | 456 | 596.0 | Domain | NR LBD | |
Tgene | ESR1 | chr6:131466556 | chr6:152415520 | ENST00000440973 | 7 | 10 | 311_547 | 456 | 596.0 | Domain | NR LBD | |
Tgene | ESR1 | chr6:131466556 | chr6:152415520 | ENST00000443427 | 6 | 9 | 311_547 | 456 | 596.0 | Domain | NR LBD | |
Tgene | ESR1 | chr6:131466556 | chr6:152415520 | ENST00000456483 | 5 | 8 | 311_547 | 344 | 484.0 | Domain | NR LBD | |
Tgene | ESR1 | chr6:131466556 | chr6:152415520 | ENST00000206249 | 5 | 8 | 251_310 | 456 | 596.0 | Region | Note=Hinge | |
Tgene | ESR1 | chr6:131466556 | chr6:152415520 | ENST00000206249 | 5 | 8 | 264_595 | 456 | 596.0 | Region | Note=Self-association | |
Tgene | ESR1 | chr6:131466556 | chr6:152415520 | ENST00000206249 | 5 | 8 | 311_595 | 456 | 596.0 | Region | Note=Transactivation AF-2 | |
Tgene | ESR1 | chr6:131466556 | chr6:152415520 | ENST00000338799 | 6 | 9 | 251_310 | 456 | 596.0 | Region | Note=Hinge | |
Tgene | ESR1 | chr6:131466556 | chr6:152415520 | ENST00000338799 | 6 | 9 | 264_595 | 456 | 596.0 | Region | Note=Self-association | |
Tgene | ESR1 | chr6:131466556 | chr6:152415520 | ENST00000338799 | 6 | 9 | 311_595 | 456 | 596.0 | Region | Note=Transactivation AF-2 | |
Tgene | ESR1 | chr6:131466556 | chr6:152415520 | ENST00000440973 | 7 | 10 | 251_310 | 456 | 596.0 | Region | Note=Hinge | |
Tgene | ESR1 | chr6:131466556 | chr6:152415520 | ENST00000440973 | 7 | 10 | 264_595 | 456 | 596.0 | Region | Note=Self-association | |
Tgene | ESR1 | chr6:131466556 | chr6:152415520 | ENST00000440973 | 7 | 10 | 311_595 | 456 | 596.0 | Region | Note=Transactivation AF-2 | |
Tgene | ESR1 | chr6:131466556 | chr6:152415520 | ENST00000443427 | 6 | 9 | 251_310 | 456 | 596.0 | Region | Note=Hinge | |
Tgene | ESR1 | chr6:131466556 | chr6:152415520 | ENST00000443427 | 6 | 9 | 264_595 | 456 | 596.0 | Region | Note=Self-association | |
Tgene | ESR1 | chr6:131466556 | chr6:152415520 | ENST00000443427 | 6 | 9 | 311_595 | 456 | 596.0 | Region | Note=Transactivation AF-2 | |
Tgene | ESR1 | chr6:131466556 | chr6:152415520 | ENST00000456483 | 5 | 8 | 251_310 | 344 | 484.0 | Region | Note=Hinge | |
Tgene | ESR1 | chr6:131466556 | chr6:152415520 | ENST00000456483 | 5 | 8 | 264_595 | 344 | 484.0 | Region | Note=Self-association | |
Tgene | ESR1 | chr6:131466556 | chr6:152415520 | ENST00000456483 | 5 | 8 | 311_595 | 344 | 484.0 | Region | Note=Transactivation AF-2 | |
Tgene | ESR1 | chr6:131466556 | chr6:152415520 | ENST00000206249 | 5 | 8 | 185_205 | 456 | 596.0 | Zinc finger | NR C4-type | |
Tgene | ESR1 | chr6:131466556 | chr6:152415520 | ENST00000206249 | 5 | 8 | 221_245 | 456 | 596.0 | Zinc finger | NR C4-type | |
Tgene | ESR1 | chr6:131466556 | chr6:152415520 | ENST00000338799 | 6 | 9 | 185_205 | 456 | 596.0 | Zinc finger | NR C4-type | |
Tgene | ESR1 | chr6:131466556 | chr6:152415520 | ENST00000338799 | 6 | 9 | 221_245 | 456 | 596.0 | Zinc finger | NR C4-type | |
Tgene | ESR1 | chr6:131466556 | chr6:152415520 | ENST00000440973 | 7 | 10 | 185_205 | 456 | 596.0 | Zinc finger | NR C4-type | |
Tgene | ESR1 | chr6:131466556 | chr6:152415520 | ENST00000440973 | 7 | 10 | 221_245 | 456 | 596.0 | Zinc finger | NR C4-type | |
Tgene | ESR1 | chr6:131466556 | chr6:152415520 | ENST00000443427 | 6 | 9 | 185_205 | 456 | 596.0 | Zinc finger | NR C4-type | |
Tgene | ESR1 | chr6:131466556 | chr6:152415520 | ENST00000443427 | 6 | 9 | 221_245 | 456 | 596.0 | Zinc finger | NR C4-type | |
Tgene | ESR1 | chr6:131466556 | chr6:152415520 | ENST00000456483 | 5 | 8 | 185_205 | 344 | 484.0 | Zinc finger | NR C4-type | |
Tgene | ESR1 | chr6:131466556 | chr6:152415520 | ENST00000456483 | 5 | 8 | 221_245 | 344 | 484.0 | Zinc finger | NR C4-type |
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Fusion Gene Sequence for AKAP7-ESR1 |
For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
>3361_3361_1_AKAP7-ESR1_AKAP7_chr6_131466556_ENST00000368123_ESR1_chr6_152415520_ENST00000206249_length(transcript)=4820nt_BP=96nt GAAAAAAGAAAATGTCAGAGGAATTTGAAGCCAATACTATGGATTCTCTGGTAGACATGCCATTTGCTACTGTAGATATTCAGGATGACT GTGGAAGAGTGTACACATTTCTGTCCAGCACCCTGAAGTCTCTGGAAGAGAAGGACCATATCCACCGAGTCCTGGACAAGATCACAGACA CTTTGATCCACCTGATGGCCAAGGCAGGCCTGACCCTGCAGCAGCAGCACCAGCGGCTGGCCCAGCTCCTCCTCATCCTCTCCCACATCA GGCACATGAGTAACAAAGGCATGGAGCATCTGTACAGCATGAAGTGCAAGAACGTGGTGCCCCTCTATGACCTGCTGCTGGAGATGCTGG ACGCCCACCGCCTACATGCGCCCACTAGCCGTGGAGGGGCATCCGTGGAGGAGACGGACCAAAGCCACTTGGCCACTGCGGGCTCTACTT CATCGCATTCCTTGCAAAAGTATTACATCACGGGGGAGGCAGAGGGTTTCCCTGCCACGGTCTGAGAGCTCCCTGGCTCCCACACGGTTC AGATAATCCCTGCTGCATTTTACCCTCATCATGCACCACTTTAGCCAAATTCTGTCTCCTGCATACACTCCGGCATGCATCCAACACCAA TGGCTTTCTAGATGAGTGGCCATTCATTTGCTTGCTCAGTTCTTAGTGGCACATCTTCTGTCTTCTGTTGGGAACAGCCAAAGGGATTCC AAGGCTAAATCTTTGTAACAGCTCTCTTTCCCCCTTGCTATGTTACTAAGCGTGAGGATTCCCGTAGCTCTTCACAGCTGAACTCAGTCT ATGGGTTGGGGCTCAGATAACTCTGTGCATTTAAGCTACTTGTAGAGACCCAGGCCTGGAGAGTAGACATTTTGCCTCTGATAAGCACTT TTTAAATGGCTCTAAGAATAAGCCACAGCAAAGAATTTAAAGTGGCTCCTTTAATTGGTGACTTGGAGAAAGCTAGGTCAAGGGTTTATT ATAGCACCCTCTTGTATTCCTATGGCAATGCATCCTTTTATGAAAGTGGTACACCTTAAAGCTTTTATATGACTGTAGCAGAGTATCTGG TGATTGTCAATTCATTCCCCCTATAGGAATACAAGGGGCACACAGGGAAGGCAGATCCCCTAGTTGGCAAGACTATTTTAACTTGATACA CTGCAGATTCAGATGTGCTGAAAGCTCTGCCTCTGGCTTTCCGGTCATGGGTTCCAGTTAATTCATGCCTCCCATGGACCTATGGAGAGC AGCAAGTTGATCTTAGTTAAGTCTCCCTATATGAGGGATAAGTTCCTGATTTTTGTTTTTATTTTTGTGTTACAAAAGAAAGCCCTCCCT CCCTGAACTTGCAGTAAGGTCAGCTTCAGGACCTGTTCCAGTGGGCACTGTACTTGGATCTTCCCGGCGTGTGTGTGCCTTACACAGGGG TGAACTGTTCACTGTGGTGATGCATGATGAGGGTAAATGGTAGTTGAAAGGAGCAGGGGCCCTGGTGTTGCATTTAGCCCTGGGGCATGG AGCTGAACAGTACTTGTGCAGGATTGTTGTGGCTACTAGAGAACAAGAGGGAAAGTAGGGCAGAAACTGGATACAGTTCTGAGGCACAGC CAGACTTGCTCAGGGTGGCCCTGCCACAGGCTGCAGCTACCTAGGAACATTCCTTGCAGACCCCGCATTGCCCTTTGGGGGTGCCCTGGG ATCCCTGGGGTAGTCCAGCTCTTCTTCATTTCCCAGCGTGGCCCTGGTTGGAAGAAGCAGCTGTCACAGCTGCTGTAGACAGCTGTGTTC CTACAATTGGCCCAGCACCCTGGGGCACGGGAGAAGGGTGGGGACCGTTGCTGTCACTACTCAGGCTGACTGGGGCCTGGTCAGATTACG TATGCCCTTGGTGGTTTAGAGATAATCCAAAATCAGGGTTTGGTTTGGGGAAGAAAATCCTCCCCCTTCCTCCCCCGCCCCGTTCCCTAC CGCCTCCACTCCTGCCAGCTCATTTCCTTCAATTTCCTTTGACCTATAGGCTAAAAAAGAAAGGCTCATTCCAGCCACAGGGCAGCCTTC CCTGGGCCTTTGCTTCTCTAGCACAATTATGGGTTACTTCCTTTTTCTTAACAAAAAAGAATGTTTGATTTCCTCTGGGTGACCTTATTG TCTGTAATTGAAACCCTATTGAGAGGTGATGTCTGTGTTAGCCAATGACCCAGGTGAGCTGCTCGGGCTTCTCTTGGTATGTCTTGTTTG GAAAAGTGGATTTCATTCATTTCTGATTGTCCAGTTAAGTGATCACCAAAGGACTGAGAATCTGGGAGGGCAAAAAAAAAAAAAAAGTTT TTATGTGCACTTAAATTTGGGGACAATTTTATGTATCTGTGTTAAGGATATGTTTAAGAACATAATTCTTTTGTTGCTGTTTGTTTAAGA AGCACCTTAGTTTGTTTAAGAAGCACCTTATATAGTATAATATATATTTTTTTGAAATTACATTGCTTGTTTATCAGACAATTGAATGTA GTAATTCTGTTCTGGATTTAATTTGACTGGGTTAACATGCAAAAACCAAGGAAAAATATTTAGTTTTTTTTTTTTTTTTTGTATACTTTT CAAGCTACCTTGTCATGTATACAGTCATTTATGCCTAAAGCCTGGTGATTATTCATTTAAATGAAGATCACATTTCATATCAACTTTTGT ATCCACAGTAGACAAAATAGCACTAATCCAGATGCCTATTGTTGGATACTGAATGACAGACAATCTTATGTAGCAAAGATTATGCCTGAA AAGGAAAATTATTCAGGGCAGCTAATTTTGCTTTTACCAAAATATCAGTAGTAATATTTTTGGACAGTAGCTAATGGGTCAGTGGGTTCT TTTTAATGTTTATACTTAGATTTTCTTTTAAAAAAATTAAAATAAAACAAAAAAAAATTTCTAGGACTAGACGATGTAATACCAGCTAAA GCCAAACAATTATACAGTGGAAGGTTTTACATTATTCATCCAATGTGTTTCTATTCATGTTAAGATACTACTACATTTGAAGTGGGCAGA GAACATCAGATGATTGAAATGTTCGCCCAGGGGTCTCCAGCAACTTTGGAAATCTCTTTGTATTTTTACTTGAAGTGCCACTAATGGACA GCAGATATTTTCTGGCTGATGTTGGTATTGGGTGTAGGAACATGATTTAAAAAAAAACTCTTGCCTCTGCTTTCCCCCACTCTGAGGCAA GTTAAAATGTAAAAGATGTGATTTATCTGGGGGGCTCAGGTATGGTGGGGAAGTGGATTCAGGAATCTGGGGAATGGCAAATATATTAAG AAGAGTATTGAAAGTATTTGGAGGAAAATGGTTAATTCTGGGTGTGCACCAGGGTTCAGTAGAGTCCACTTCTGCCCTGGAGACCACAAA TCAACTAGCTCCATTTACAGCCATTTCTAAAATGGCAGCTTCAGTTCTAGAGAAGAAAGAACAACATCAGCAGTAAAGTCCATGGAATAG CTAGTGGTCTGTGTTTCTTTTCGCCATTGCCTAGCTTGCCGTAATGATTCTATAATGCCATCATGCAGCAATTATGAGAGGCTAGGTCAT CCAAAGAGAAGACCCTATCAATGTAGGTTGCAAAATCTAACCCCTAAGGAAGTGCAGTCTTTGATTTGATTTCCCTAGTAACCTTGCAGA TATGTTTAACCAAGCCATAGCCCATGCCTTTTGAGGGCTGAACAAATAAGGGACTTACTGATAATTTACTTTTGATCACATTAAGGTGTT CTCACCTTGAAATCTTATACACTGAAATGGCCATTGATTTAGGCCACTGGCTTAGAGTACTCCTTCCCCTGCATGACACTGATTACAAAT ACTTTCCTATTCATACTTTCCAATTATGAGATGGACTGTGGGTACTGGGAGTGATCACTAACACCATAGTAATGTCTAATATTCACAGGC AGATCTGCTTGGGGAAGCTAGTTATGTGAAAGGCAAATAGAGTCATACAGTAGCTCAAAAGGCAACCATAATTCTCTTTGGTGCAGGTCT TGGGAGCGTGATCTAGATTACACTGCACCATTCCCAAGTTAATCCCCTGAAAACTTACTCTCAACTGGAGCAAATGAACTTTGGTCCCAA ATATCCATCTTTTCAGTAGCGTTAATTATGCTCTGTTTCCAACTGCATTTCCTTTCCAATTGAATTAAAGTGTGGCCTCGTTTTTAGTCA TTTAAAATTGTTTTCTAAGTAATTGCTGCCTCTATTATGGCACTTCAATTTTGCACTGTCTTTTGAGATTCAAGAAAAATTTCTATTCTT TTTTTTGCATCCAATTGTGCCTGAACTTTTAAAATATGTAAATGCTGCCATGTTCCAAACCCATCGTCAGTGTGTGTGTTTAGAGCTGTG CACCCTAGAAACAACATATTGTCCCATGAGCAGGTGCCTGAGACACAGACCCCTTTGCATTCACAGAGAGGTCATTGGTTATAGAGACTT GAATTAATAAGTGACATTATGCCAGTTTCTGTTCTCTCACAGGTGATAAACAATGCTTTTTGTGCACTACATACTCTTCAGTGTAGAGCT CTTGTTTTATGGGAAAAGGCTCAAATGCCAAATTGTGTTTGATGGATTAATATGCCCTTTTGCCGATGCATACTATTACTGATGTGACTC GGTTTTGTCGCAGCTTTGCTTTGTTTAATGAAACACACTTGTAAACCTCTTTTGCACTTTGAAAAAGAATCCAGCGGGATGCTCGAGCAC >3361_3361_1_AKAP7-ESR1_AKAP7_chr6_131466556_ENST00000368123_ESR1_chr6_152415520_ENST00000206249_length(amino acids)=167AA_BP=29 MSEEFEANTMDSLVDMPFATVDIQDDCGRVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMS -------------------------------------------------------------- >3361_3361_2_AKAP7-ESR1_AKAP7_chr6_131466556_ENST00000368123_ESR1_chr6_152415520_ENST00000338799_length(transcript)=602nt_BP=96nt GAAAAAAGAAAATGTCAGAGGAATTTGAAGCCAATACTATGGATTCTCTGGTAGACATGCCATTTGCTACTGTAGATATTCAGGATGACT GTGGAAGAGTGTACACATTTCTGTCCAGCACCCTGAAGTCTCTGGAAGAGAAGGACCATATCCACCGAGTCCTGGACAAGATCACAGACA CTTTGATCCACCTGATGGCCAAGGCAGGCCTGACCCTGCAGCAGCAGCACCAGCGGCTGGCCCAGCTCCTCCTCATCCTCTCCCACATCA GGCACATGAGTAACAAAGGCATGGAGCATCTGTACAGCATGAAGTGCAAGAACGTGGTGCCCCTCTATGACCTGCTGCTGGAGATGCTGG ACGCCCACCGCCTACATGCGCCCACTAGCCGTGGAGGGGCATCCGTGGAGGAGACGGACCAAAGCCACTTGGCCACTGCGGGCTCTACTT CATCGCATTCCTTGCAAAAGTATTACATCACGGGGGAGGCAGAGGGTTTCCCTGCCACGGTCTGAGAGCTCCCTGGCTCCCACACGGTTC >3361_3361_2_AKAP7-ESR1_AKAP7_chr6_131466556_ENST00000368123_ESR1_chr6_152415520_ENST00000338799_length(amino acids)=167AA_BP=29 MSEEFEANTMDSLVDMPFATVDIQDDCGRVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMS -------------------------------------------------------------- >3361_3361_3_AKAP7-ESR1_AKAP7_chr6_131466556_ENST00000368123_ESR1_chr6_152415520_ENST00000406599_length(transcript)=527nt_BP=96nt GAAAAAAGAAAATGTCAGAGGAATTTGAAGCCAATACTATGGATTCTCTGGTAGACATGCCATTTGCTACTGTAGATATTCAGGATGACT GTGGAAGAGTGTACACATTTCTGTCCAGCACCCTGAAGTCTCTGGAAGAGAAGGACCATATCCACCGAGTCCTGGACAAGATCACAGACA CTTTGATCCACCTGATGGCCAAGGCAGGCCTGACCCTGCAGCAGCAGCACCAGCGGCTGGCCCAGCTCCTCCTCATCCTCTCCCACATCA GGCACATGAGTAACAAAGGCATGGAGCATCTGTACAGCATGAAGTGCAAGAACGTGGTGCCCCTCTATGACCTGCTGCTGGAGATGCTGG ACGCCCACCGCCTACATGCGCCCACTAGCCGTGGAGGGGCATCCGTGGAGGAGACGGACCAAAGCCACTTGGCCACTGCGGGCTCTACTT >3361_3361_3_AKAP7-ESR1_AKAP7_chr6_131466556_ENST00000368123_ESR1_chr6_152415520_ENST00000406599_length(amino acids)=167AA_BP=29 MSEEFEANTMDSLVDMPFATVDIQDDCGRVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMS -------------------------------------------------------------- >3361_3361_4_AKAP7-ESR1_AKAP7_chr6_131466556_ENST00000368123_ESR1_chr6_152415520_ENST00000440973_length(transcript)=4823nt_BP=96nt GAAAAAAGAAAATGTCAGAGGAATTTGAAGCCAATACTATGGATTCTCTGGTAGACATGCCATTTGCTACTGTAGATATTCAGGATGACT GTGGAAGAGTGTACACATTTCTGTCCAGCACCCTGAAGTCTCTGGAAGAGAAGGACCATATCCACCGAGTCCTGGACAAGATCACAGACA CTTTGATCCACCTGATGGCCAAGGCAGGCCTGACCCTGCAGCAGCAGCACCAGCGGCTGGCCCAGCTCCTCCTCATCCTCTCCCACATCA GGCACATGAGTAACAAAGGCATGGAGCATCTGTACAGCATGAAGTGCAAGAACGTGGTGCCCCTCTATGACCTGCTGCTGGAGATGCTGG ACGCCCACCGCCTACATGCGCCCACTAGCCGTGGAGGGGCATCCGTGGAGGAGACGGACCAAAGCCACTTGGCCACTGCGGGCTCTACTT CATCGCATTCCTTGCAAAAGTATTACATCACGGGGGAGGCAGAGGGTTTCCCTGCCACGGTCTGAGAGCTCCCTGGCTCCCACACGGTTC AGATAATCCCTGCTGCATTTTACCCTCATCATGCACCACTTTAGCCAAATTCTGTCTCCTGCATACACTCCGGCATGCATCCAACACCAA TGGCTTTCTAGATGAGTGGCCATTCATTTGCTTGCTCAGTTCTTAGTGGCACATCTTCTGTCTTCTGTTGGGAACAGCCAAAGGGATTCC AAGGCTAAATCTTTGTAACAGCTCTCTTTCCCCCTTGCTATGTTACTAAGCGTGAGGATTCCCGTAGCTCTTCACAGCTGAACTCAGTCT ATGGGTTGGGGCTCAGATAACTCTGTGCATTTAAGCTACTTGTAGAGACCCAGGCCTGGAGAGTAGACATTTTGCCTCTGATAAGCACTT TTTAAATGGCTCTAAGAATAAGCCACAGCAAAGAATTTAAAGTGGCTCCTTTAATTGGTGACTTGGAGAAAGCTAGGTCAAGGGTTTATT ATAGCACCCTCTTGTATTCCTATGGCAATGCATCCTTTTATGAAAGTGGTACACCTTAAAGCTTTTATATGACTGTAGCAGAGTATCTGG TGATTGTCAATTCATTCCCCCTATAGGAATACAAGGGGCACACAGGGAAGGCAGATCCCCTAGTTGGCAAGACTATTTTAACTTGATACA CTGCAGATTCAGATGTGCTGAAAGCTCTGCCTCTGGCTTTCCGGTCATGGGTTCCAGTTAATTCATGCCTCCCATGGACCTATGGAGAGC AGCAAGTTGATCTTAGTTAAGTCTCCCTATATGAGGGATAAGTTCCTGATTTTTGTTTTTATTTTTGTGTTACAAAAGAAAGCCCTCCCT CCCTGAACTTGCAGTAAGGTCAGCTTCAGGACCTGTTCCAGTGGGCACTGTACTTGGATCTTCCCGGCGTGTGTGTGCCTTACACAGGGG TGAACTGTTCACTGTGGTGATGCATGATGAGGGTAAATGGTAGTTGAAAGGAGCAGGGGCCCTGGTGTTGCATTTAGCCCTGGGGCATGG AGCTGAACAGTACTTGTGCAGGATTGTTGTGGCTACTAGAGAACAAGAGGGAAAGTAGGGCAGAAACTGGATACAGTTCTGAGGCACAGC CAGACTTGCTCAGGGTGGCCCTGCCACAGGCTGCAGCTACCTAGGAACATTCCTTGCAGACCCCGCATTGCCCTTTGGGGGTGCCCTGGG ATCCCTGGGGTAGTCCAGCTCTTCTTCATTTCCCAGCGTGGCCCTGGTTGGAAGAAGCAGCTGTCACAGCTGCTGTAGACAGCTGTGTTC CTACAATTGGCCCAGCACCCTGGGGCACGGGAGAAGGGTGGGGACCGTTGCTGTCACTACTCAGGCTGACTGGGGCCTGGTCAGATTACG TATGCCCTTGGTGGTTTAGAGATAATCCAAAATCAGGGTTTGGTTTGGGGAAGAAAATCCTCCCCCTTCCTCCCCCGCCCCGTTCCCTAC CGCCTCCACTCCTGCCAGCTCATTTCCTTCAATTTCCTTTGACCTATAGGCTAAAAAAGAAAGGCTCATTCCAGCCACAGGGCAGCCTTC CCTGGGCCTTTGCTTCTCTAGCACAATTATGGGTTACTTCCTTTTTCTTAACAAAAAAGAATGTTTGATTTCCTCTGGGTGACCTTATTG TCTGTAATTGAAACCCTATTGAGAGGTGATGTCTGTGTTAGCCAATGACCCAGGTGAGCTGCTCGGGCTTCTCTTGGTATGTCTTGTTTG GAAAAGTGGATTTCATTCATTTCTGATTGTCCAGTTAAGTGATCACCAAAGGACTGAGAATCTGGGAGGGCAAAAAAAAAAAAAAAGTTT TTATGTGCACTTAAATTTGGGGACAATTTTATGTATCTGTGTTAAGGATATGTTTAAGAACATAATTCTTTTGTTGCTGTTTGTTTAAGA AGCACCTTAGTTTGTTTAAGAAGCACCTTATATAGTATAATATATATTTTTTTGAAATTACATTGCTTGTTTATCAGACAATTGAATGTA GTAATTCTGTTCTGGATTTAATTTGACTGGGTTAACATGCAAAAACCAAGGAAAAATATTTAGTTTTTTTTTTTTTTTTTGTATACTTTT CAAGCTACCTTGTCATGTATACAGTCATTTATGCCTAAAGCCTGGTGATTATTCATTTAAATGAAGATCACATTTCATATCAACTTTTGT ATCCACAGTAGACAAAATAGCACTAATCCAGATGCCTATTGTTGGATACTGAATGACAGACAATCTTATGTAGCAAAGATTATGCCTGAA AAGGAAAATTATTCAGGGCAGCTAATTTTGCTTTTACCAAAATATCAGTAGTAATATTTTTGGACAGTAGCTAATGGGTCAGTGGGTTCT TTTTAATGTTTATACTTAGATTTTCTTTTAAAAAAATTAAAATAAAACAAAAAAAAATTTCTAGGACTAGACGATGTAATACCAGCTAAA GCCAAACAATTATACAGTGGAAGGTTTTACATTATTCATCCAATGTGTTTCTATTCATGTTAAGATACTACTACATTTGAAGTGGGCAGA GAACATCAGATGATTGAAATGTTCGCCCAGGGGTCTCCAGCAACTTTGGAAATCTCTTTGTATTTTTACTTGAAGTGCCACTAATGGACA GCAGATATTTTCTGGCTGATGTTGGTATTGGGTGTAGGAACATGATTTAAAAAAAAACTCTTGCCTCTGCTTTCCCCCACTCTGAGGCAA GTTAAAATGTAAAAGATGTGATTTATCTGGGGGGCTCAGGTATGGTGGGGAAGTGGATTCAGGAATCTGGGGAATGGCAAATATATTAAG AAGAGTATTGAAAGTATTTGGAGGAAAATGGTTAATTCTGGGTGTGCACCAGGGTTCAGTAGAGTCCACTTCTGCCCTGGAGACCACAAA TCAACTAGCTCCATTTACAGCCATTTCTAAAATGGCAGCTTCAGTTCTAGAGAAGAAAGAACAACATCAGCAGTAAAGTCCATGGAATAG CTAGTGGTCTGTGTTTCTTTTCGCCATTGCCTAGCTTGCCGTAATGATTCTATAATGCCATCATGCAGCAATTATGAGAGGCTAGGTCAT CCAAAGAGAAGACCCTATCAATGTAGGTTGCAAAATCTAACCCCTAAGGAAGTGCAGTCTTTGATTTGATTTCCCTAGTAACCTTGCAGA TATGTTTAACCAAGCCATAGCCCATGCCTTTTGAGGGCTGAACAAATAAGGGACTTACTGATAATTTACTTTTGATCACATTAAGGTGTT CTCACCTTGAAATCTTATACACTGAAATGGCCATTGATTTAGGCCACTGGCTTAGAGTACTCCTTCCCCTGCATGACACTGATTACAAAT ACTTTCCTATTCATACTTTCCAATTATGAGATGGACTGTGGGTACTGGGAGTGATCACTAACACCATAGTAATGTCTAATATTCACAGGC AGATCTGCTTGGGGAAGCTAGTTATGTGAAAGGCAAATAGAGTCATACAGTAGCTCAAAAGGCAACCATAATTCTCTTTGGTGCAGGTCT TGGGAGCGTGATCTAGATTACACTGCACCATTCCCAAGTTAATCCCCTGAAAACTTACTCTCAACTGGAGCAAATGAACTTTGGTCCCAA ATATCCATCTTTTCAGTAGCGTTAATTATGCTCTGTTTCCAACTGCATTTCCTTTCCAATTGAATTAAAGTGTGGCCTCGTTTTTAGTCA TTTAAAATTGTTTTCTAAGTAATTGCTGCCTCTATTATGGCACTTCAATTTTGCACTGTCTTTTGAGATTCAAGAAAAATTTCTATTCTT TTTTTTGCATCCAATTGTGCCTGAACTTTTAAAATATGTAAATGCTGCCATGTTCCAAACCCATCGTCAGTGTGTGTGTTTAGAGCTGTG CACCCTAGAAACAACATATTGTCCCATGAGCAGGTGCCTGAGACACAGACCCCTTTGCATTCACAGAGAGGTCATTGGTTATAGAGACTT GAATTAATAAGTGACATTATGCCAGTTTCTGTTCTCTCACAGGTGATAAACAATGCTTTTTGTGCACTACATACTCTTCAGTGTAGAGCT CTTGTTTTATGGGAAAAGGCTCAAATGCCAAATTGTGTTTGATGGATTAATATGCCCTTTTGCCGATGCATACTATTACTGATGTGACTC GGTTTTGTCGCAGCTTTGCTTTGTTTAATGAAACACACTTGTAAACCTCTTTTGCACTTTGAAAAAGAATCCAGCGGGATGCTCGAGCAC >3361_3361_4_AKAP7-ESR1_AKAP7_chr6_131466556_ENST00000368123_ESR1_chr6_152415520_ENST00000440973_length(amino acids)=167AA_BP=29 MSEEFEANTMDSLVDMPFATVDIQDDCGRVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMS -------------------------------------------------------------- >3361_3361_5_AKAP7-ESR1_AKAP7_chr6_131466556_ENST00000368123_ESR1_chr6_152415520_ENST00000443427_length(transcript)=4823nt_BP=96nt GAAAAAAGAAAATGTCAGAGGAATTTGAAGCCAATACTATGGATTCTCTGGTAGACATGCCATTTGCTACTGTAGATATTCAGGATGACT GTGGAAGAGTGTACACATTTCTGTCCAGCACCCTGAAGTCTCTGGAAGAGAAGGACCATATCCACCGAGTCCTGGACAAGATCACAGACA CTTTGATCCACCTGATGGCCAAGGCAGGCCTGACCCTGCAGCAGCAGCACCAGCGGCTGGCCCAGCTCCTCCTCATCCTCTCCCACATCA GGCACATGAGTAACAAAGGCATGGAGCATCTGTACAGCATGAAGTGCAAGAACGTGGTGCCCCTCTATGACCTGCTGCTGGAGATGCTGG ACGCCCACCGCCTACATGCGCCCACTAGCCGTGGAGGGGCATCCGTGGAGGAGACGGACCAAAGCCACTTGGCCACTGCGGGCTCTACTT CATCGCATTCCTTGCAAAAGTATTACATCACGGGGGAGGCAGAGGGTTTCCCTGCCACGGTCTGAGAGCTCCCTGGCTCCCACACGGTTC AGATAATCCCTGCTGCATTTTACCCTCATCATGCACCACTTTAGCCAAATTCTGTCTCCTGCATACACTCCGGCATGCATCCAACACCAA TGGCTTTCTAGATGAGTGGCCATTCATTTGCTTGCTCAGTTCTTAGTGGCACATCTTCTGTCTTCTGTTGGGAACAGCCAAAGGGATTCC AAGGCTAAATCTTTGTAACAGCTCTCTTTCCCCCTTGCTATGTTACTAAGCGTGAGGATTCCCGTAGCTCTTCACAGCTGAACTCAGTCT ATGGGTTGGGGCTCAGATAACTCTGTGCATTTAAGCTACTTGTAGAGACCCAGGCCTGGAGAGTAGACATTTTGCCTCTGATAAGCACTT TTTAAATGGCTCTAAGAATAAGCCACAGCAAAGAATTTAAAGTGGCTCCTTTAATTGGTGACTTGGAGAAAGCTAGGTCAAGGGTTTATT ATAGCACCCTCTTGTATTCCTATGGCAATGCATCCTTTTATGAAAGTGGTACACCTTAAAGCTTTTATATGACTGTAGCAGAGTATCTGG TGATTGTCAATTCATTCCCCCTATAGGAATACAAGGGGCACACAGGGAAGGCAGATCCCCTAGTTGGCAAGACTATTTTAACTTGATACA CTGCAGATTCAGATGTGCTGAAAGCTCTGCCTCTGGCTTTCCGGTCATGGGTTCCAGTTAATTCATGCCTCCCATGGACCTATGGAGAGC AGCAAGTTGATCTTAGTTAAGTCTCCCTATATGAGGGATAAGTTCCTGATTTTTGTTTTTATTTTTGTGTTACAAAAGAAAGCCCTCCCT CCCTGAACTTGCAGTAAGGTCAGCTTCAGGACCTGTTCCAGTGGGCACTGTACTTGGATCTTCCCGGCGTGTGTGTGCCTTACACAGGGG TGAACTGTTCACTGTGGTGATGCATGATGAGGGTAAATGGTAGTTGAAAGGAGCAGGGGCCCTGGTGTTGCATTTAGCCCTGGGGCATGG AGCTGAACAGTACTTGTGCAGGATTGTTGTGGCTACTAGAGAACAAGAGGGAAAGTAGGGCAGAAACTGGATACAGTTCTGAGGCACAGC CAGACTTGCTCAGGGTGGCCCTGCCACAGGCTGCAGCTACCTAGGAACATTCCTTGCAGACCCCGCATTGCCCTTTGGGGGTGCCCTGGG ATCCCTGGGGTAGTCCAGCTCTTCTTCATTTCCCAGCGTGGCCCTGGTTGGAAGAAGCAGCTGTCACAGCTGCTGTAGACAGCTGTGTTC CTACAATTGGCCCAGCACCCTGGGGCACGGGAGAAGGGTGGGGACCGTTGCTGTCACTACTCAGGCTGACTGGGGCCTGGTCAGATTACG TATGCCCTTGGTGGTTTAGAGATAATCCAAAATCAGGGTTTGGTTTGGGGAAGAAAATCCTCCCCCTTCCTCCCCCGCCCCGTTCCCTAC CGCCTCCACTCCTGCCAGCTCATTTCCTTCAATTTCCTTTGACCTATAGGCTAAAAAAGAAAGGCTCATTCCAGCCACAGGGCAGCCTTC CCTGGGCCTTTGCTTCTCTAGCACAATTATGGGTTACTTCCTTTTTCTTAACAAAAAAGAATGTTTGATTTCCTCTGGGTGACCTTATTG TCTGTAATTGAAACCCTATTGAGAGGTGATGTCTGTGTTAGCCAATGACCCAGGTGAGCTGCTCGGGCTTCTCTTGGTATGTCTTGTTTG GAAAAGTGGATTTCATTCATTTCTGATTGTCCAGTTAAGTGATCACCAAAGGACTGAGAATCTGGGAGGGCAAAAAAAAAAAAAAAGTTT TTATGTGCACTTAAATTTGGGGACAATTTTATGTATCTGTGTTAAGGATATGTTTAAGAACATAATTCTTTTGTTGCTGTTTGTTTAAGA AGCACCTTAGTTTGTTTAAGAAGCACCTTATATAGTATAATATATATTTTTTTGAAATTACATTGCTTGTTTATCAGACAATTGAATGTA GTAATTCTGTTCTGGATTTAATTTGACTGGGTTAACATGCAAAAACCAAGGAAAAATATTTAGTTTTTTTTTTTTTTTTTGTATACTTTT CAAGCTACCTTGTCATGTATACAGTCATTTATGCCTAAAGCCTGGTGATTATTCATTTAAATGAAGATCACATTTCATATCAACTTTTGT ATCCACAGTAGACAAAATAGCACTAATCCAGATGCCTATTGTTGGATACTGAATGACAGACAATCTTATGTAGCAAAGATTATGCCTGAA AAGGAAAATTATTCAGGGCAGCTAATTTTGCTTTTACCAAAATATCAGTAGTAATATTTTTGGACAGTAGCTAATGGGTCAGTGGGTTCT TTTTAATGTTTATACTTAGATTTTCTTTTAAAAAAATTAAAATAAAACAAAAAAAAATTTCTAGGACTAGACGATGTAATACCAGCTAAA GCCAAACAATTATACAGTGGAAGGTTTTACATTATTCATCCAATGTGTTTCTATTCATGTTAAGATACTACTACATTTGAAGTGGGCAGA GAACATCAGATGATTGAAATGTTCGCCCAGGGGTCTCCAGCAACTTTGGAAATCTCTTTGTATTTTTACTTGAAGTGCCACTAATGGACA GCAGATATTTTCTGGCTGATGTTGGTATTGGGTGTAGGAACATGATTTAAAAAAAAACTCTTGCCTCTGCTTTCCCCCACTCTGAGGCAA GTTAAAATGTAAAAGATGTGATTTATCTGGGGGGCTCAGGTATGGTGGGGAAGTGGATTCAGGAATCTGGGGAATGGCAAATATATTAAG AAGAGTATTGAAAGTATTTGGAGGAAAATGGTTAATTCTGGGTGTGCACCAGGGTTCAGTAGAGTCCACTTCTGCCCTGGAGACCACAAA TCAACTAGCTCCATTTACAGCCATTTCTAAAATGGCAGCTTCAGTTCTAGAGAAGAAAGAACAACATCAGCAGTAAAGTCCATGGAATAG CTAGTGGTCTGTGTTTCTTTTCGCCATTGCCTAGCTTGCCGTAATGATTCTATAATGCCATCATGCAGCAATTATGAGAGGCTAGGTCAT CCAAAGAGAAGACCCTATCAATGTAGGTTGCAAAATCTAACCCCTAAGGAAGTGCAGTCTTTGATTTGATTTCCCTAGTAACCTTGCAGA TATGTTTAACCAAGCCATAGCCCATGCCTTTTGAGGGCTGAACAAATAAGGGACTTACTGATAATTTACTTTTGATCACATTAAGGTGTT CTCACCTTGAAATCTTATACACTGAAATGGCCATTGATTTAGGCCACTGGCTTAGAGTACTCCTTCCCCTGCATGACACTGATTACAAAT ACTTTCCTATTCATACTTTCCAATTATGAGATGGACTGTGGGTACTGGGAGTGATCACTAACACCATAGTAATGTCTAATATTCACAGGC AGATCTGCTTGGGGAAGCTAGTTATGTGAAAGGCAAATAGAGTCATACAGTAGCTCAAAAGGCAACCATAATTCTCTTTGGTGCAGGTCT TGGGAGCGTGATCTAGATTACACTGCACCATTCCCAAGTTAATCCCCTGAAAACTTACTCTCAACTGGAGCAAATGAACTTTGGTCCCAA ATATCCATCTTTTCAGTAGCGTTAATTATGCTCTGTTTCCAACTGCATTTCCTTTCCAATTGAATTAAAGTGTGGCCTCGTTTTTAGTCA TTTAAAATTGTTTTCTAAGTAATTGCTGCCTCTATTATGGCACTTCAATTTTGCACTGTCTTTTGAGATTCAAGAAAAATTTCTATTCTT TTTTTTGCATCCAATTGTGCCTGAACTTTTAAAATATGTAAATGCTGCCATGTTCCAAACCCATCGTCAGTGTGTGTGTTTAGAGCTGTG CACCCTAGAAACAACATATTGTCCCATGAGCAGGTGCCTGAGACACAGACCCCTTTGCATTCACAGAGAGGTCATTGGTTATAGAGACTT GAATTAATAAGTGACATTATGCCAGTTTCTGTTCTCTCACAGGTGATAAACAATGCTTTTTGTGCACTACATACTCTTCAGTGTAGAGCT CTTGTTTTATGGGAAAAGGCTCAAATGCCAAATTGTGTTTGATGGATTAATATGCCCTTTTGCCGATGCATACTATTACTGATGTGACTC GGTTTTGTCGCAGCTTTGCTTTGTTTAATGAAACACACTTGTAAACCTCTTTTGCACTTTGAAAAAGAATCCAGCGGGATGCTCGAGCAC >3361_3361_5_AKAP7-ESR1_AKAP7_chr6_131466556_ENST00000368123_ESR1_chr6_152415520_ENST00000443427_length(amino acids)=167AA_BP=29 MSEEFEANTMDSLVDMPFATVDIQDDCGRVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMS -------------------------------------------------------------- >3361_3361_6_AKAP7-ESR1_AKAP7_chr6_131466556_ENST00000368123_ESR1_chr6_152415520_ENST00000456483_length(transcript)=4823nt_BP=96nt GAAAAAAGAAAATGTCAGAGGAATTTGAAGCCAATACTATGGATTCTCTGGTAGACATGCCATTTGCTACTGTAGATATTCAGGATGACT GTGGAAGAGTGTACACATTTCTGTCCAGCACCCTGAAGTCTCTGGAAGAGAAGGACCATATCCACCGAGTCCTGGACAAGATCACAGACA CTTTGATCCACCTGATGGCCAAGGCAGGCCTGACCCTGCAGCAGCAGCACCAGCGGCTGGCCCAGCTCCTCCTCATCCTCTCCCACATCA GGCACATGAGTAACAAAGGCATGGAGCATCTGTACAGCATGAAGTGCAAGAACGTGGTGCCCCTCTATGACCTGCTGCTGGAGATGCTGG ACGCCCACCGCCTACATGCGCCCACTAGCCGTGGAGGGGCATCCGTGGAGGAGACGGACCAAAGCCACTTGGCCACTGCGGGCTCTACTT CATCGCATTCCTTGCAAAAGTATTACATCACGGGGGAGGCAGAGGGTTTCCCTGCCACGGTCTGAGAGCTCCCTGGCTCCCACACGGTTC AGATAATCCCTGCTGCATTTTACCCTCATCATGCACCACTTTAGCCAAATTCTGTCTCCTGCATACACTCCGGCATGCATCCAACACCAA TGGCTTTCTAGATGAGTGGCCATTCATTTGCTTGCTCAGTTCTTAGTGGCACATCTTCTGTCTTCTGTTGGGAACAGCCAAAGGGATTCC AAGGCTAAATCTTTGTAACAGCTCTCTTTCCCCCTTGCTATGTTACTAAGCGTGAGGATTCCCGTAGCTCTTCACAGCTGAACTCAGTCT ATGGGTTGGGGCTCAGATAACTCTGTGCATTTAAGCTACTTGTAGAGACCCAGGCCTGGAGAGTAGACATTTTGCCTCTGATAAGCACTT TTTAAATGGCTCTAAGAATAAGCCACAGCAAAGAATTTAAAGTGGCTCCTTTAATTGGTGACTTGGAGAAAGCTAGGTCAAGGGTTTATT ATAGCACCCTCTTGTATTCCTATGGCAATGCATCCTTTTATGAAAGTGGTACACCTTAAAGCTTTTATATGACTGTAGCAGAGTATCTGG TGATTGTCAATTCATTCCCCCTATAGGAATACAAGGGGCACACAGGGAAGGCAGATCCCCTAGTTGGCAAGACTATTTTAACTTGATACA CTGCAGATTCAGATGTGCTGAAAGCTCTGCCTCTGGCTTTCCGGTCATGGGTTCCAGTTAATTCATGCCTCCCATGGACCTATGGAGAGC AGCAAGTTGATCTTAGTTAAGTCTCCCTATATGAGGGATAAGTTCCTGATTTTTGTTTTTATTTTTGTGTTACAAAAGAAAGCCCTCCCT CCCTGAACTTGCAGTAAGGTCAGCTTCAGGACCTGTTCCAGTGGGCACTGTACTTGGATCTTCCCGGCGTGTGTGTGCCTTACACAGGGG TGAACTGTTCACTGTGGTGATGCATGATGAGGGTAAATGGTAGTTGAAAGGAGCAGGGGCCCTGGTGTTGCATTTAGCCCTGGGGCATGG AGCTGAACAGTACTTGTGCAGGATTGTTGTGGCTACTAGAGAACAAGAGGGAAAGTAGGGCAGAAACTGGATACAGTTCTGAGGCACAGC CAGACTTGCTCAGGGTGGCCCTGCCACAGGCTGCAGCTACCTAGGAACATTCCTTGCAGACCCCGCATTGCCCTTTGGGGGTGCCCTGGG ATCCCTGGGGTAGTCCAGCTCTTCTTCATTTCCCAGCGTGGCCCTGGTTGGAAGAAGCAGCTGTCACAGCTGCTGTAGACAGCTGTGTTC CTACAATTGGCCCAGCACCCTGGGGCACGGGAGAAGGGTGGGGACCGTTGCTGTCACTACTCAGGCTGACTGGGGCCTGGTCAGATTACG TATGCCCTTGGTGGTTTAGAGATAATCCAAAATCAGGGTTTGGTTTGGGGAAGAAAATCCTCCCCCTTCCTCCCCCGCCCCGTTCCCTAC CGCCTCCACTCCTGCCAGCTCATTTCCTTCAATTTCCTTTGACCTATAGGCTAAAAAAGAAAGGCTCATTCCAGCCACAGGGCAGCCTTC CCTGGGCCTTTGCTTCTCTAGCACAATTATGGGTTACTTCCTTTTTCTTAACAAAAAAGAATGTTTGATTTCCTCTGGGTGACCTTATTG TCTGTAATTGAAACCCTATTGAGAGGTGATGTCTGTGTTAGCCAATGACCCAGGTGAGCTGCTCGGGCTTCTCTTGGTATGTCTTGTTTG GAAAAGTGGATTTCATTCATTTCTGATTGTCCAGTTAAGTGATCACCAAAGGACTGAGAATCTGGGAGGGCAAAAAAAAAAAAAAAGTTT TTATGTGCACTTAAATTTGGGGACAATTTTATGTATCTGTGTTAAGGATATGTTTAAGAACATAATTCTTTTGTTGCTGTTTGTTTAAGA AGCACCTTAGTTTGTTTAAGAAGCACCTTATATAGTATAATATATATTTTTTTGAAATTACATTGCTTGTTTATCAGACAATTGAATGTA GTAATTCTGTTCTGGATTTAATTTGACTGGGTTAACATGCAAAAACCAAGGAAAAATATTTAGTTTTTTTTTTTTTTTTTGTATACTTTT CAAGCTACCTTGTCATGTATACAGTCATTTATGCCTAAAGCCTGGTGATTATTCATTTAAATGAAGATCACATTTCATATCAACTTTTGT ATCCACAGTAGACAAAATAGCACTAATCCAGATGCCTATTGTTGGATACTGAATGACAGACAATCTTATGTAGCAAAGATTATGCCTGAA AAGGAAAATTATTCAGGGCAGCTAATTTTGCTTTTACCAAAATATCAGTAGTAATATTTTTGGACAGTAGCTAATGGGTCAGTGGGTTCT TTTTAATGTTTATACTTAGATTTTCTTTTAAAAAAATTAAAATAAAACAAAAAAAAATTTCTAGGACTAGACGATGTAATACCAGCTAAA GCCAAACAATTATACAGTGGAAGGTTTTACATTATTCATCCAATGTGTTTCTATTCATGTTAAGATACTACTACATTTGAAGTGGGCAGA GAACATCAGATGATTGAAATGTTCGCCCAGGGGTCTCCAGCAACTTTGGAAATCTCTTTGTATTTTTACTTGAAGTGCCACTAATGGACA GCAGATATTTTCTGGCTGATGTTGGTATTGGGTGTAGGAACATGATTTAAAAAAAAACTCTTGCCTCTGCTTTCCCCCACTCTGAGGCAA GTTAAAATGTAAAAGATGTGATTTATCTGGGGGGCTCAGGTATGGTGGGGAAGTGGATTCAGGAATCTGGGGAATGGCAAATATATTAAG AAGAGTATTGAAAGTATTTGGAGGAAAATGGTTAATTCTGGGTGTGCACCAGGGTTCAGTAGAGTCCACTTCTGCCCTGGAGACCACAAA TCAACTAGCTCCATTTACAGCCATTTCTAAAATGGCAGCTTCAGTTCTAGAGAAGAAAGAACAACATCAGCAGTAAAGTCCATGGAATAG CTAGTGGTCTGTGTTTCTTTTCGCCATTGCCTAGCTTGCCGTAATGATTCTATAATGCCATCATGCAGCAATTATGAGAGGCTAGGTCAT CCAAAGAGAAGACCCTATCAATGTAGGTTGCAAAATCTAACCCCTAAGGAAGTGCAGTCTTTGATTTGATTTCCCTAGTAACCTTGCAGA TATGTTTAACCAAGCCATAGCCCATGCCTTTTGAGGGCTGAACAAATAAGGGACTTACTGATAATTTACTTTTGATCACATTAAGGTGTT CTCACCTTGAAATCTTATACACTGAAATGGCCATTGATTTAGGCCACTGGCTTAGAGTACTCCTTCCCCTGCATGACACTGATTACAAAT ACTTTCCTATTCATACTTTCCAATTATGAGATGGACTGTGGGTACTGGGAGTGATCACTAACACCATAGTAATGTCTAATATTCACAGGC AGATCTGCTTGGGGAAGCTAGTTATGTGAAAGGCAAATAGAGTCATACAGTAGCTCAAAAGGCAACCATAATTCTCTTTGGTGCAGGTCT TGGGAGCGTGATCTAGATTACACTGCACCATTCCCAAGTTAATCCCCTGAAAACTTACTCTCAACTGGAGCAAATGAACTTTGGTCCCAA ATATCCATCTTTTCAGTAGCGTTAATTATGCTCTGTTTCCAACTGCATTTCCTTTCCAATTGAATTAAAGTGTGGCCTCGTTTTTAGTCA TTTAAAATTGTTTTCTAAGTAATTGCTGCCTCTATTATGGCACTTCAATTTTGCACTGTCTTTTGAGATTCAAGAAAAATTTCTATTCTT TTTTTTGCATCCAATTGTGCCTGAACTTTTAAAATATGTAAATGCTGCCATGTTCCAAACCCATCGTCAGTGTGTGTGTTTAGAGCTGTG CACCCTAGAAACAACATATTGTCCCATGAGCAGGTGCCTGAGACACAGACCCCTTTGCATTCACAGAGAGGTCATTGGTTATAGAGACTT GAATTAATAAGTGACATTATGCCAGTTTCTGTTCTCTCACAGGTGATAAACAATGCTTTTTGTGCACTACATACTCTTCAGTGTAGAGCT CTTGTTTTATGGGAAAAGGCTCAAATGCCAAATTGTGTTTGATGGATTAATATGCCCTTTTGCCGATGCATACTATTACTGATGTGACTC GGTTTTGTCGCAGCTTTGCTTTGTTTAATGAAACACACTTGTAAACCTCTTTTGCACTTTGAAAAAGAATCCAGCGGGATGCTCGAGCAC >3361_3361_6_AKAP7-ESR1_AKAP7_chr6_131466556_ENST00000368123_ESR1_chr6_152415520_ENST00000456483_length(amino acids)=167AA_BP=29 MSEEFEANTMDSLVDMPFATVDIQDDCGRVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMS -------------------------------------------------------------- >3361_3361_7_AKAP7-ESR1_AKAP7_chr6_131466556_ENST00000431975_ESR1_chr6_152415520_ENST00000206249_length(transcript)=4973nt_BP=249nt GCCCTGGCCTCCGCCTCGGCCTCGCCTCCAGCCCCGGGACGCGGCCCGCCACCGCCGCTGCCGCCAGCCCAGACGCGCCGCCCGCATGCG CCGCGACCATGGAGCGCCCCGAAGCGGGAGGAATTAATTCCAATGAGTGTGAAAATGTATCAAGAAAAAAGAAAATGTCAGAGGAATTTG AAGCCAATACTATGGATTCTCTGGTAGACATGCCATTTGCTACTGTAGATATTCAGGATGACTGTGGAAGAGTGTACACATTTCTGTCCA GCACCCTGAAGTCTCTGGAAGAGAAGGACCATATCCACCGAGTCCTGGACAAGATCACAGACACTTTGATCCACCTGATGGCCAAGGCAG GCCTGACCCTGCAGCAGCAGCACCAGCGGCTGGCCCAGCTCCTCCTCATCCTCTCCCACATCAGGCACATGAGTAACAAAGGCATGGAGC ATCTGTACAGCATGAAGTGCAAGAACGTGGTGCCCCTCTATGACCTGCTGCTGGAGATGCTGGACGCCCACCGCCTACATGCGCCCACTA GCCGTGGAGGGGCATCCGTGGAGGAGACGGACCAAAGCCACTTGGCCACTGCGGGCTCTACTTCATCGCATTCCTTGCAAAAGTATTACA TCACGGGGGAGGCAGAGGGTTTCCCTGCCACGGTCTGAGAGCTCCCTGGCTCCCACACGGTTCAGATAATCCCTGCTGCATTTTACCCTC ATCATGCACCACTTTAGCCAAATTCTGTCTCCTGCATACACTCCGGCATGCATCCAACACCAATGGCTTTCTAGATGAGTGGCCATTCAT TTGCTTGCTCAGTTCTTAGTGGCACATCTTCTGTCTTCTGTTGGGAACAGCCAAAGGGATTCCAAGGCTAAATCTTTGTAACAGCTCTCT TTCCCCCTTGCTATGTTACTAAGCGTGAGGATTCCCGTAGCTCTTCACAGCTGAACTCAGTCTATGGGTTGGGGCTCAGATAACTCTGTG CATTTAAGCTACTTGTAGAGACCCAGGCCTGGAGAGTAGACATTTTGCCTCTGATAAGCACTTTTTAAATGGCTCTAAGAATAAGCCACA GCAAAGAATTTAAAGTGGCTCCTTTAATTGGTGACTTGGAGAAAGCTAGGTCAAGGGTTTATTATAGCACCCTCTTGTATTCCTATGGCA ATGCATCCTTTTATGAAAGTGGTACACCTTAAAGCTTTTATATGACTGTAGCAGAGTATCTGGTGATTGTCAATTCATTCCCCCTATAGG AATACAAGGGGCACACAGGGAAGGCAGATCCCCTAGTTGGCAAGACTATTTTAACTTGATACACTGCAGATTCAGATGTGCTGAAAGCTC TGCCTCTGGCTTTCCGGTCATGGGTTCCAGTTAATTCATGCCTCCCATGGACCTATGGAGAGCAGCAAGTTGATCTTAGTTAAGTCTCCC TATATGAGGGATAAGTTCCTGATTTTTGTTTTTATTTTTGTGTTACAAAAGAAAGCCCTCCCTCCCTGAACTTGCAGTAAGGTCAGCTTC AGGACCTGTTCCAGTGGGCACTGTACTTGGATCTTCCCGGCGTGTGTGTGCCTTACACAGGGGTGAACTGTTCACTGTGGTGATGCATGA TGAGGGTAAATGGTAGTTGAAAGGAGCAGGGGCCCTGGTGTTGCATTTAGCCCTGGGGCATGGAGCTGAACAGTACTTGTGCAGGATTGT TGTGGCTACTAGAGAACAAGAGGGAAAGTAGGGCAGAAACTGGATACAGTTCTGAGGCACAGCCAGACTTGCTCAGGGTGGCCCTGCCAC AGGCTGCAGCTACCTAGGAACATTCCTTGCAGACCCCGCATTGCCCTTTGGGGGTGCCCTGGGATCCCTGGGGTAGTCCAGCTCTTCTTC ATTTCCCAGCGTGGCCCTGGTTGGAAGAAGCAGCTGTCACAGCTGCTGTAGACAGCTGTGTTCCTACAATTGGCCCAGCACCCTGGGGCA CGGGAGAAGGGTGGGGACCGTTGCTGTCACTACTCAGGCTGACTGGGGCCTGGTCAGATTACGTATGCCCTTGGTGGTTTAGAGATAATC CAAAATCAGGGTTTGGTTTGGGGAAGAAAATCCTCCCCCTTCCTCCCCCGCCCCGTTCCCTACCGCCTCCACTCCTGCCAGCTCATTTCC TTCAATTTCCTTTGACCTATAGGCTAAAAAAGAAAGGCTCATTCCAGCCACAGGGCAGCCTTCCCTGGGCCTTTGCTTCTCTAGCACAAT TATGGGTTACTTCCTTTTTCTTAACAAAAAAGAATGTTTGATTTCCTCTGGGTGACCTTATTGTCTGTAATTGAAACCCTATTGAGAGGT GATGTCTGTGTTAGCCAATGACCCAGGTGAGCTGCTCGGGCTTCTCTTGGTATGTCTTGTTTGGAAAAGTGGATTTCATTCATTTCTGAT TGTCCAGTTAAGTGATCACCAAAGGACTGAGAATCTGGGAGGGCAAAAAAAAAAAAAAAGTTTTTATGTGCACTTAAATTTGGGGACAAT TTTATGTATCTGTGTTAAGGATATGTTTAAGAACATAATTCTTTTGTTGCTGTTTGTTTAAGAAGCACCTTAGTTTGTTTAAGAAGCACC TTATATAGTATAATATATATTTTTTTGAAATTACATTGCTTGTTTATCAGACAATTGAATGTAGTAATTCTGTTCTGGATTTAATTTGAC TGGGTTAACATGCAAAAACCAAGGAAAAATATTTAGTTTTTTTTTTTTTTTTTGTATACTTTTCAAGCTACCTTGTCATGTATACAGTCA TTTATGCCTAAAGCCTGGTGATTATTCATTTAAATGAAGATCACATTTCATATCAACTTTTGTATCCACAGTAGACAAAATAGCACTAAT CCAGATGCCTATTGTTGGATACTGAATGACAGACAATCTTATGTAGCAAAGATTATGCCTGAAAAGGAAAATTATTCAGGGCAGCTAATT TTGCTTTTACCAAAATATCAGTAGTAATATTTTTGGACAGTAGCTAATGGGTCAGTGGGTTCTTTTTAATGTTTATACTTAGATTTTCTT TTAAAAAAATTAAAATAAAACAAAAAAAAATTTCTAGGACTAGACGATGTAATACCAGCTAAAGCCAAACAATTATACAGTGGAAGGTTT TACATTATTCATCCAATGTGTTTCTATTCATGTTAAGATACTACTACATTTGAAGTGGGCAGAGAACATCAGATGATTGAAATGTTCGCC CAGGGGTCTCCAGCAACTTTGGAAATCTCTTTGTATTTTTACTTGAAGTGCCACTAATGGACAGCAGATATTTTCTGGCTGATGTTGGTA TTGGGTGTAGGAACATGATTTAAAAAAAAACTCTTGCCTCTGCTTTCCCCCACTCTGAGGCAAGTTAAAATGTAAAAGATGTGATTTATC TGGGGGGCTCAGGTATGGTGGGGAAGTGGATTCAGGAATCTGGGGAATGGCAAATATATTAAGAAGAGTATTGAAAGTATTTGGAGGAAA ATGGTTAATTCTGGGTGTGCACCAGGGTTCAGTAGAGTCCACTTCTGCCCTGGAGACCACAAATCAACTAGCTCCATTTACAGCCATTTC TAAAATGGCAGCTTCAGTTCTAGAGAAGAAAGAACAACATCAGCAGTAAAGTCCATGGAATAGCTAGTGGTCTGTGTTTCTTTTCGCCAT TGCCTAGCTTGCCGTAATGATTCTATAATGCCATCATGCAGCAATTATGAGAGGCTAGGTCATCCAAAGAGAAGACCCTATCAATGTAGG TTGCAAAATCTAACCCCTAAGGAAGTGCAGTCTTTGATTTGATTTCCCTAGTAACCTTGCAGATATGTTTAACCAAGCCATAGCCCATGC CTTTTGAGGGCTGAACAAATAAGGGACTTACTGATAATTTACTTTTGATCACATTAAGGTGTTCTCACCTTGAAATCTTATACACTGAAA TGGCCATTGATTTAGGCCACTGGCTTAGAGTACTCCTTCCCCTGCATGACACTGATTACAAATACTTTCCTATTCATACTTTCCAATTAT GAGATGGACTGTGGGTACTGGGAGTGATCACTAACACCATAGTAATGTCTAATATTCACAGGCAGATCTGCTTGGGGAAGCTAGTTATGT GAAAGGCAAATAGAGTCATACAGTAGCTCAAAAGGCAACCATAATTCTCTTTGGTGCAGGTCTTGGGAGCGTGATCTAGATTACACTGCA CCATTCCCAAGTTAATCCCCTGAAAACTTACTCTCAACTGGAGCAAATGAACTTTGGTCCCAAATATCCATCTTTTCAGTAGCGTTAATT ATGCTCTGTTTCCAACTGCATTTCCTTTCCAATTGAATTAAAGTGTGGCCTCGTTTTTAGTCATTTAAAATTGTTTTCTAAGTAATTGCT GCCTCTATTATGGCACTTCAATTTTGCACTGTCTTTTGAGATTCAAGAAAAATTTCTATTCTTTTTTTTGCATCCAATTGTGCCTGAACT TTTAAAATATGTAAATGCTGCCATGTTCCAAACCCATCGTCAGTGTGTGTGTTTAGAGCTGTGCACCCTAGAAACAACATATTGTCCCAT GAGCAGGTGCCTGAGACACAGACCCCTTTGCATTCACAGAGAGGTCATTGGTTATAGAGACTTGAATTAATAAGTGACATTATGCCAGTT TCTGTTCTCTCACAGGTGATAAACAATGCTTTTTGTGCACTACATACTCTTCAGTGTAGAGCTCTTGTTTTATGGGAAAAGGCTCAAATG CCAAATTGTGTTTGATGGATTAATATGCCCTTTTGCCGATGCATACTATTACTGATGTGACTCGGTTTTGTCGCAGCTTTGCTTTGTTTA ATGAAACACACTTGTAAACCTCTTTTGCACTTTGAAAAAGAATCCAGCGGGATGCTCGAGCACCTGTAAACAATTTTCTCAACCTATTTG >3361_3361_7_AKAP7-ESR1_AKAP7_chr6_131466556_ENST00000431975_ESR1_chr6_152415520_ENST00000206249_length(amino acids)=189AA_BP=51 MERPEAGGINSNECENVSRKKKMSEEFEANTMDSLVDMPFATVDIQDDCGRVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLT LQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLLLEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITG -------------------------------------------------------------- >3361_3361_8_AKAP7-ESR1_AKAP7_chr6_131466556_ENST00000431975_ESR1_chr6_152415520_ENST00000338799_length(transcript)=755nt_BP=249nt GCCCTGGCCTCCGCCTCGGCCTCGCCTCCAGCCCCGGGACGCGGCCCGCCACCGCCGCTGCCGCCAGCCCAGACGCGCCGCCCGCATGCG CCGCGACCATGGAGCGCCCCGAAGCGGGAGGAATTAATTCCAATGAGTGTGAAAATGTATCAAGAAAAAAGAAAATGTCAGAGGAATTTG AAGCCAATACTATGGATTCTCTGGTAGACATGCCATTTGCTACTGTAGATATTCAGGATGACTGTGGAAGAGTGTACACATTTCTGTCCA GCACCCTGAAGTCTCTGGAAGAGAAGGACCATATCCACCGAGTCCTGGACAAGATCACAGACACTTTGATCCACCTGATGGCCAAGGCAG GCCTGACCCTGCAGCAGCAGCACCAGCGGCTGGCCCAGCTCCTCCTCATCCTCTCCCACATCAGGCACATGAGTAACAAAGGCATGGAGC ATCTGTACAGCATGAAGTGCAAGAACGTGGTGCCCCTCTATGACCTGCTGCTGGAGATGCTGGACGCCCACCGCCTACATGCGCCCACTA GCCGTGGAGGGGCATCCGTGGAGGAGACGGACCAAAGCCACTTGGCCACTGCGGGCTCTACTTCATCGCATTCCTTGCAAAAGTATTACA TCACGGGGGAGGCAGAGGGTTTCCCTGCCACGGTCTGAGAGCTCCCTGGCTCCCACACGGTTCAGATAATCCCTGCTGCATTTTACCCTC >3361_3361_8_AKAP7-ESR1_AKAP7_chr6_131466556_ENST00000431975_ESR1_chr6_152415520_ENST00000338799_length(amino acids)=189AA_BP=51 MERPEAGGINSNECENVSRKKKMSEEFEANTMDSLVDMPFATVDIQDDCGRVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLT LQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLLLEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITG -------------------------------------------------------------- >3361_3361_9_AKAP7-ESR1_AKAP7_chr6_131466556_ENST00000431975_ESR1_chr6_152415520_ENST00000406599_length(transcript)=680nt_BP=249nt GCCCTGGCCTCCGCCTCGGCCTCGCCTCCAGCCCCGGGACGCGGCCCGCCACCGCCGCTGCCGCCAGCCCAGACGCGCCGCCCGCATGCG CCGCGACCATGGAGCGCCCCGAAGCGGGAGGAATTAATTCCAATGAGTGTGAAAATGTATCAAGAAAAAAGAAAATGTCAGAGGAATTTG AAGCCAATACTATGGATTCTCTGGTAGACATGCCATTTGCTACTGTAGATATTCAGGATGACTGTGGAAGAGTGTACACATTTCTGTCCA GCACCCTGAAGTCTCTGGAAGAGAAGGACCATATCCACCGAGTCCTGGACAAGATCACAGACACTTTGATCCACCTGATGGCCAAGGCAG GCCTGACCCTGCAGCAGCAGCACCAGCGGCTGGCCCAGCTCCTCCTCATCCTCTCCCACATCAGGCACATGAGTAACAAAGGCATGGAGC ATCTGTACAGCATGAAGTGCAAGAACGTGGTGCCCCTCTATGACCTGCTGCTGGAGATGCTGGACGCCCACCGCCTACATGCGCCCACTA GCCGTGGAGGGGCATCCGTGGAGGAGACGGACCAAAGCCACTTGGCCACTGCGGGCTCTACTTCATCGCATTCCTTGCAAAAGTATTACA >3361_3361_9_AKAP7-ESR1_AKAP7_chr6_131466556_ENST00000431975_ESR1_chr6_152415520_ENST00000406599_length(amino acids)=189AA_BP=51 MERPEAGGINSNECENVSRKKKMSEEFEANTMDSLVDMPFATVDIQDDCGRVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLT LQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLLLEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITG -------------------------------------------------------------- >3361_3361_10_AKAP7-ESR1_AKAP7_chr6_131466556_ENST00000431975_ESR1_chr6_152415520_ENST00000440973_length(transcript)=4976nt_BP=249nt GCCCTGGCCTCCGCCTCGGCCTCGCCTCCAGCCCCGGGACGCGGCCCGCCACCGCCGCTGCCGCCAGCCCAGACGCGCCGCCCGCATGCG CCGCGACCATGGAGCGCCCCGAAGCGGGAGGAATTAATTCCAATGAGTGTGAAAATGTATCAAGAAAAAAGAAAATGTCAGAGGAATTTG AAGCCAATACTATGGATTCTCTGGTAGACATGCCATTTGCTACTGTAGATATTCAGGATGACTGTGGAAGAGTGTACACATTTCTGTCCA GCACCCTGAAGTCTCTGGAAGAGAAGGACCATATCCACCGAGTCCTGGACAAGATCACAGACACTTTGATCCACCTGATGGCCAAGGCAG GCCTGACCCTGCAGCAGCAGCACCAGCGGCTGGCCCAGCTCCTCCTCATCCTCTCCCACATCAGGCACATGAGTAACAAAGGCATGGAGC ATCTGTACAGCATGAAGTGCAAGAACGTGGTGCCCCTCTATGACCTGCTGCTGGAGATGCTGGACGCCCACCGCCTACATGCGCCCACTA GCCGTGGAGGGGCATCCGTGGAGGAGACGGACCAAAGCCACTTGGCCACTGCGGGCTCTACTTCATCGCATTCCTTGCAAAAGTATTACA TCACGGGGGAGGCAGAGGGTTTCCCTGCCACGGTCTGAGAGCTCCCTGGCTCCCACACGGTTCAGATAATCCCTGCTGCATTTTACCCTC ATCATGCACCACTTTAGCCAAATTCTGTCTCCTGCATACACTCCGGCATGCATCCAACACCAATGGCTTTCTAGATGAGTGGCCATTCAT TTGCTTGCTCAGTTCTTAGTGGCACATCTTCTGTCTTCTGTTGGGAACAGCCAAAGGGATTCCAAGGCTAAATCTTTGTAACAGCTCTCT TTCCCCCTTGCTATGTTACTAAGCGTGAGGATTCCCGTAGCTCTTCACAGCTGAACTCAGTCTATGGGTTGGGGCTCAGATAACTCTGTG CATTTAAGCTACTTGTAGAGACCCAGGCCTGGAGAGTAGACATTTTGCCTCTGATAAGCACTTTTTAAATGGCTCTAAGAATAAGCCACA GCAAAGAATTTAAAGTGGCTCCTTTAATTGGTGACTTGGAGAAAGCTAGGTCAAGGGTTTATTATAGCACCCTCTTGTATTCCTATGGCA ATGCATCCTTTTATGAAAGTGGTACACCTTAAAGCTTTTATATGACTGTAGCAGAGTATCTGGTGATTGTCAATTCATTCCCCCTATAGG AATACAAGGGGCACACAGGGAAGGCAGATCCCCTAGTTGGCAAGACTATTTTAACTTGATACACTGCAGATTCAGATGTGCTGAAAGCTC TGCCTCTGGCTTTCCGGTCATGGGTTCCAGTTAATTCATGCCTCCCATGGACCTATGGAGAGCAGCAAGTTGATCTTAGTTAAGTCTCCC TATATGAGGGATAAGTTCCTGATTTTTGTTTTTATTTTTGTGTTACAAAAGAAAGCCCTCCCTCCCTGAACTTGCAGTAAGGTCAGCTTC AGGACCTGTTCCAGTGGGCACTGTACTTGGATCTTCCCGGCGTGTGTGTGCCTTACACAGGGGTGAACTGTTCACTGTGGTGATGCATGA TGAGGGTAAATGGTAGTTGAAAGGAGCAGGGGCCCTGGTGTTGCATTTAGCCCTGGGGCATGGAGCTGAACAGTACTTGTGCAGGATTGT TGTGGCTACTAGAGAACAAGAGGGAAAGTAGGGCAGAAACTGGATACAGTTCTGAGGCACAGCCAGACTTGCTCAGGGTGGCCCTGCCAC AGGCTGCAGCTACCTAGGAACATTCCTTGCAGACCCCGCATTGCCCTTTGGGGGTGCCCTGGGATCCCTGGGGTAGTCCAGCTCTTCTTC ATTTCCCAGCGTGGCCCTGGTTGGAAGAAGCAGCTGTCACAGCTGCTGTAGACAGCTGTGTTCCTACAATTGGCCCAGCACCCTGGGGCA CGGGAGAAGGGTGGGGACCGTTGCTGTCACTACTCAGGCTGACTGGGGCCTGGTCAGATTACGTATGCCCTTGGTGGTTTAGAGATAATC CAAAATCAGGGTTTGGTTTGGGGAAGAAAATCCTCCCCCTTCCTCCCCCGCCCCGTTCCCTACCGCCTCCACTCCTGCCAGCTCATTTCC TTCAATTTCCTTTGACCTATAGGCTAAAAAAGAAAGGCTCATTCCAGCCACAGGGCAGCCTTCCCTGGGCCTTTGCTTCTCTAGCACAAT TATGGGTTACTTCCTTTTTCTTAACAAAAAAGAATGTTTGATTTCCTCTGGGTGACCTTATTGTCTGTAATTGAAACCCTATTGAGAGGT GATGTCTGTGTTAGCCAATGACCCAGGTGAGCTGCTCGGGCTTCTCTTGGTATGTCTTGTTTGGAAAAGTGGATTTCATTCATTTCTGAT TGTCCAGTTAAGTGATCACCAAAGGACTGAGAATCTGGGAGGGCAAAAAAAAAAAAAAAGTTTTTATGTGCACTTAAATTTGGGGACAAT TTTATGTATCTGTGTTAAGGATATGTTTAAGAACATAATTCTTTTGTTGCTGTTTGTTTAAGAAGCACCTTAGTTTGTTTAAGAAGCACC TTATATAGTATAATATATATTTTTTTGAAATTACATTGCTTGTTTATCAGACAATTGAATGTAGTAATTCTGTTCTGGATTTAATTTGAC TGGGTTAACATGCAAAAACCAAGGAAAAATATTTAGTTTTTTTTTTTTTTTTTGTATACTTTTCAAGCTACCTTGTCATGTATACAGTCA TTTATGCCTAAAGCCTGGTGATTATTCATTTAAATGAAGATCACATTTCATATCAACTTTTGTATCCACAGTAGACAAAATAGCACTAAT CCAGATGCCTATTGTTGGATACTGAATGACAGACAATCTTATGTAGCAAAGATTATGCCTGAAAAGGAAAATTATTCAGGGCAGCTAATT TTGCTTTTACCAAAATATCAGTAGTAATATTTTTGGACAGTAGCTAATGGGTCAGTGGGTTCTTTTTAATGTTTATACTTAGATTTTCTT TTAAAAAAATTAAAATAAAACAAAAAAAAATTTCTAGGACTAGACGATGTAATACCAGCTAAAGCCAAACAATTATACAGTGGAAGGTTT TACATTATTCATCCAATGTGTTTCTATTCATGTTAAGATACTACTACATTTGAAGTGGGCAGAGAACATCAGATGATTGAAATGTTCGCC CAGGGGTCTCCAGCAACTTTGGAAATCTCTTTGTATTTTTACTTGAAGTGCCACTAATGGACAGCAGATATTTTCTGGCTGATGTTGGTA TTGGGTGTAGGAACATGATTTAAAAAAAAACTCTTGCCTCTGCTTTCCCCCACTCTGAGGCAAGTTAAAATGTAAAAGATGTGATTTATC TGGGGGGCTCAGGTATGGTGGGGAAGTGGATTCAGGAATCTGGGGAATGGCAAATATATTAAGAAGAGTATTGAAAGTATTTGGAGGAAA ATGGTTAATTCTGGGTGTGCACCAGGGTTCAGTAGAGTCCACTTCTGCCCTGGAGACCACAAATCAACTAGCTCCATTTACAGCCATTTC TAAAATGGCAGCTTCAGTTCTAGAGAAGAAAGAACAACATCAGCAGTAAAGTCCATGGAATAGCTAGTGGTCTGTGTTTCTTTTCGCCAT TGCCTAGCTTGCCGTAATGATTCTATAATGCCATCATGCAGCAATTATGAGAGGCTAGGTCATCCAAAGAGAAGACCCTATCAATGTAGG TTGCAAAATCTAACCCCTAAGGAAGTGCAGTCTTTGATTTGATTTCCCTAGTAACCTTGCAGATATGTTTAACCAAGCCATAGCCCATGC CTTTTGAGGGCTGAACAAATAAGGGACTTACTGATAATTTACTTTTGATCACATTAAGGTGTTCTCACCTTGAAATCTTATACACTGAAA TGGCCATTGATTTAGGCCACTGGCTTAGAGTACTCCTTCCCCTGCATGACACTGATTACAAATACTTTCCTATTCATACTTTCCAATTAT GAGATGGACTGTGGGTACTGGGAGTGATCACTAACACCATAGTAATGTCTAATATTCACAGGCAGATCTGCTTGGGGAAGCTAGTTATGT GAAAGGCAAATAGAGTCATACAGTAGCTCAAAAGGCAACCATAATTCTCTTTGGTGCAGGTCTTGGGAGCGTGATCTAGATTACACTGCA CCATTCCCAAGTTAATCCCCTGAAAACTTACTCTCAACTGGAGCAAATGAACTTTGGTCCCAAATATCCATCTTTTCAGTAGCGTTAATT ATGCTCTGTTTCCAACTGCATTTCCTTTCCAATTGAATTAAAGTGTGGCCTCGTTTTTAGTCATTTAAAATTGTTTTCTAAGTAATTGCT GCCTCTATTATGGCACTTCAATTTTGCACTGTCTTTTGAGATTCAAGAAAAATTTCTATTCTTTTTTTTGCATCCAATTGTGCCTGAACT TTTAAAATATGTAAATGCTGCCATGTTCCAAACCCATCGTCAGTGTGTGTGTTTAGAGCTGTGCACCCTAGAAACAACATATTGTCCCAT GAGCAGGTGCCTGAGACACAGACCCCTTTGCATTCACAGAGAGGTCATTGGTTATAGAGACTTGAATTAATAAGTGACATTATGCCAGTT TCTGTTCTCTCACAGGTGATAAACAATGCTTTTTGTGCACTACATACTCTTCAGTGTAGAGCTCTTGTTTTATGGGAAAAGGCTCAAATG CCAAATTGTGTTTGATGGATTAATATGCCCTTTTGCCGATGCATACTATTACTGATGTGACTCGGTTTTGTCGCAGCTTTGCTTTGTTTA ATGAAACACACTTGTAAACCTCTTTTGCACTTTGAAAAAGAATCCAGCGGGATGCTCGAGCACCTGTAAACAATTTTCTCAACCTATTTG >3361_3361_10_AKAP7-ESR1_AKAP7_chr6_131466556_ENST00000431975_ESR1_chr6_152415520_ENST00000440973_length(amino acids)=189AA_BP=51 MERPEAGGINSNECENVSRKKKMSEEFEANTMDSLVDMPFATVDIQDDCGRVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLT LQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLLLEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITG -------------------------------------------------------------- >3361_3361_11_AKAP7-ESR1_AKAP7_chr6_131466556_ENST00000431975_ESR1_chr6_152415520_ENST00000443427_length(transcript)=4976nt_BP=249nt GCCCTGGCCTCCGCCTCGGCCTCGCCTCCAGCCCCGGGACGCGGCCCGCCACCGCCGCTGCCGCCAGCCCAGACGCGCCGCCCGCATGCG CCGCGACCATGGAGCGCCCCGAAGCGGGAGGAATTAATTCCAATGAGTGTGAAAATGTATCAAGAAAAAAGAAAATGTCAGAGGAATTTG AAGCCAATACTATGGATTCTCTGGTAGACATGCCATTTGCTACTGTAGATATTCAGGATGACTGTGGAAGAGTGTACACATTTCTGTCCA GCACCCTGAAGTCTCTGGAAGAGAAGGACCATATCCACCGAGTCCTGGACAAGATCACAGACACTTTGATCCACCTGATGGCCAAGGCAG GCCTGACCCTGCAGCAGCAGCACCAGCGGCTGGCCCAGCTCCTCCTCATCCTCTCCCACATCAGGCACATGAGTAACAAAGGCATGGAGC ATCTGTACAGCATGAAGTGCAAGAACGTGGTGCCCCTCTATGACCTGCTGCTGGAGATGCTGGACGCCCACCGCCTACATGCGCCCACTA GCCGTGGAGGGGCATCCGTGGAGGAGACGGACCAAAGCCACTTGGCCACTGCGGGCTCTACTTCATCGCATTCCTTGCAAAAGTATTACA TCACGGGGGAGGCAGAGGGTTTCCCTGCCACGGTCTGAGAGCTCCCTGGCTCCCACACGGTTCAGATAATCCCTGCTGCATTTTACCCTC ATCATGCACCACTTTAGCCAAATTCTGTCTCCTGCATACACTCCGGCATGCATCCAACACCAATGGCTTTCTAGATGAGTGGCCATTCAT TTGCTTGCTCAGTTCTTAGTGGCACATCTTCTGTCTTCTGTTGGGAACAGCCAAAGGGATTCCAAGGCTAAATCTTTGTAACAGCTCTCT TTCCCCCTTGCTATGTTACTAAGCGTGAGGATTCCCGTAGCTCTTCACAGCTGAACTCAGTCTATGGGTTGGGGCTCAGATAACTCTGTG CATTTAAGCTACTTGTAGAGACCCAGGCCTGGAGAGTAGACATTTTGCCTCTGATAAGCACTTTTTAAATGGCTCTAAGAATAAGCCACA GCAAAGAATTTAAAGTGGCTCCTTTAATTGGTGACTTGGAGAAAGCTAGGTCAAGGGTTTATTATAGCACCCTCTTGTATTCCTATGGCA ATGCATCCTTTTATGAAAGTGGTACACCTTAAAGCTTTTATATGACTGTAGCAGAGTATCTGGTGATTGTCAATTCATTCCCCCTATAGG AATACAAGGGGCACACAGGGAAGGCAGATCCCCTAGTTGGCAAGACTATTTTAACTTGATACACTGCAGATTCAGATGTGCTGAAAGCTC TGCCTCTGGCTTTCCGGTCATGGGTTCCAGTTAATTCATGCCTCCCATGGACCTATGGAGAGCAGCAAGTTGATCTTAGTTAAGTCTCCC TATATGAGGGATAAGTTCCTGATTTTTGTTTTTATTTTTGTGTTACAAAAGAAAGCCCTCCCTCCCTGAACTTGCAGTAAGGTCAGCTTC AGGACCTGTTCCAGTGGGCACTGTACTTGGATCTTCCCGGCGTGTGTGTGCCTTACACAGGGGTGAACTGTTCACTGTGGTGATGCATGA TGAGGGTAAATGGTAGTTGAAAGGAGCAGGGGCCCTGGTGTTGCATTTAGCCCTGGGGCATGGAGCTGAACAGTACTTGTGCAGGATTGT TGTGGCTACTAGAGAACAAGAGGGAAAGTAGGGCAGAAACTGGATACAGTTCTGAGGCACAGCCAGACTTGCTCAGGGTGGCCCTGCCAC AGGCTGCAGCTACCTAGGAACATTCCTTGCAGACCCCGCATTGCCCTTTGGGGGTGCCCTGGGATCCCTGGGGTAGTCCAGCTCTTCTTC ATTTCCCAGCGTGGCCCTGGTTGGAAGAAGCAGCTGTCACAGCTGCTGTAGACAGCTGTGTTCCTACAATTGGCCCAGCACCCTGGGGCA CGGGAGAAGGGTGGGGACCGTTGCTGTCACTACTCAGGCTGACTGGGGCCTGGTCAGATTACGTATGCCCTTGGTGGTTTAGAGATAATC CAAAATCAGGGTTTGGTTTGGGGAAGAAAATCCTCCCCCTTCCTCCCCCGCCCCGTTCCCTACCGCCTCCACTCCTGCCAGCTCATTTCC TTCAATTTCCTTTGACCTATAGGCTAAAAAAGAAAGGCTCATTCCAGCCACAGGGCAGCCTTCCCTGGGCCTTTGCTTCTCTAGCACAAT TATGGGTTACTTCCTTTTTCTTAACAAAAAAGAATGTTTGATTTCCTCTGGGTGACCTTATTGTCTGTAATTGAAACCCTATTGAGAGGT GATGTCTGTGTTAGCCAATGACCCAGGTGAGCTGCTCGGGCTTCTCTTGGTATGTCTTGTTTGGAAAAGTGGATTTCATTCATTTCTGAT TGTCCAGTTAAGTGATCACCAAAGGACTGAGAATCTGGGAGGGCAAAAAAAAAAAAAAAGTTTTTATGTGCACTTAAATTTGGGGACAAT TTTATGTATCTGTGTTAAGGATATGTTTAAGAACATAATTCTTTTGTTGCTGTTTGTTTAAGAAGCACCTTAGTTTGTTTAAGAAGCACC TTATATAGTATAATATATATTTTTTTGAAATTACATTGCTTGTTTATCAGACAATTGAATGTAGTAATTCTGTTCTGGATTTAATTTGAC TGGGTTAACATGCAAAAACCAAGGAAAAATATTTAGTTTTTTTTTTTTTTTTTGTATACTTTTCAAGCTACCTTGTCATGTATACAGTCA TTTATGCCTAAAGCCTGGTGATTATTCATTTAAATGAAGATCACATTTCATATCAACTTTTGTATCCACAGTAGACAAAATAGCACTAAT CCAGATGCCTATTGTTGGATACTGAATGACAGACAATCTTATGTAGCAAAGATTATGCCTGAAAAGGAAAATTATTCAGGGCAGCTAATT TTGCTTTTACCAAAATATCAGTAGTAATATTTTTGGACAGTAGCTAATGGGTCAGTGGGTTCTTTTTAATGTTTATACTTAGATTTTCTT TTAAAAAAATTAAAATAAAACAAAAAAAAATTTCTAGGACTAGACGATGTAATACCAGCTAAAGCCAAACAATTATACAGTGGAAGGTTT TACATTATTCATCCAATGTGTTTCTATTCATGTTAAGATACTACTACATTTGAAGTGGGCAGAGAACATCAGATGATTGAAATGTTCGCC CAGGGGTCTCCAGCAACTTTGGAAATCTCTTTGTATTTTTACTTGAAGTGCCACTAATGGACAGCAGATATTTTCTGGCTGATGTTGGTA TTGGGTGTAGGAACATGATTTAAAAAAAAACTCTTGCCTCTGCTTTCCCCCACTCTGAGGCAAGTTAAAATGTAAAAGATGTGATTTATC TGGGGGGCTCAGGTATGGTGGGGAAGTGGATTCAGGAATCTGGGGAATGGCAAATATATTAAGAAGAGTATTGAAAGTATTTGGAGGAAA ATGGTTAATTCTGGGTGTGCACCAGGGTTCAGTAGAGTCCACTTCTGCCCTGGAGACCACAAATCAACTAGCTCCATTTACAGCCATTTC TAAAATGGCAGCTTCAGTTCTAGAGAAGAAAGAACAACATCAGCAGTAAAGTCCATGGAATAGCTAGTGGTCTGTGTTTCTTTTCGCCAT TGCCTAGCTTGCCGTAATGATTCTATAATGCCATCATGCAGCAATTATGAGAGGCTAGGTCATCCAAAGAGAAGACCCTATCAATGTAGG TTGCAAAATCTAACCCCTAAGGAAGTGCAGTCTTTGATTTGATTTCCCTAGTAACCTTGCAGATATGTTTAACCAAGCCATAGCCCATGC CTTTTGAGGGCTGAACAAATAAGGGACTTACTGATAATTTACTTTTGATCACATTAAGGTGTTCTCACCTTGAAATCTTATACACTGAAA TGGCCATTGATTTAGGCCACTGGCTTAGAGTACTCCTTCCCCTGCATGACACTGATTACAAATACTTTCCTATTCATACTTTCCAATTAT GAGATGGACTGTGGGTACTGGGAGTGATCACTAACACCATAGTAATGTCTAATATTCACAGGCAGATCTGCTTGGGGAAGCTAGTTATGT GAAAGGCAAATAGAGTCATACAGTAGCTCAAAAGGCAACCATAATTCTCTTTGGTGCAGGTCTTGGGAGCGTGATCTAGATTACACTGCA CCATTCCCAAGTTAATCCCCTGAAAACTTACTCTCAACTGGAGCAAATGAACTTTGGTCCCAAATATCCATCTTTTCAGTAGCGTTAATT ATGCTCTGTTTCCAACTGCATTTCCTTTCCAATTGAATTAAAGTGTGGCCTCGTTTTTAGTCATTTAAAATTGTTTTCTAAGTAATTGCT GCCTCTATTATGGCACTTCAATTTTGCACTGTCTTTTGAGATTCAAGAAAAATTTCTATTCTTTTTTTTGCATCCAATTGTGCCTGAACT TTTAAAATATGTAAATGCTGCCATGTTCCAAACCCATCGTCAGTGTGTGTGTTTAGAGCTGTGCACCCTAGAAACAACATATTGTCCCAT GAGCAGGTGCCTGAGACACAGACCCCTTTGCATTCACAGAGAGGTCATTGGTTATAGAGACTTGAATTAATAAGTGACATTATGCCAGTT TCTGTTCTCTCACAGGTGATAAACAATGCTTTTTGTGCACTACATACTCTTCAGTGTAGAGCTCTTGTTTTATGGGAAAAGGCTCAAATG CCAAATTGTGTTTGATGGATTAATATGCCCTTTTGCCGATGCATACTATTACTGATGTGACTCGGTTTTGTCGCAGCTTTGCTTTGTTTA ATGAAACACACTTGTAAACCTCTTTTGCACTTTGAAAAAGAATCCAGCGGGATGCTCGAGCACCTGTAAACAATTTTCTCAACCTATTTG >3361_3361_11_AKAP7-ESR1_AKAP7_chr6_131466556_ENST00000431975_ESR1_chr6_152415520_ENST00000443427_length(amino acids)=189AA_BP=51 MERPEAGGINSNECENVSRKKKMSEEFEANTMDSLVDMPFATVDIQDDCGRVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLT LQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLLLEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITG -------------------------------------------------------------- >3361_3361_12_AKAP7-ESR1_AKAP7_chr6_131466556_ENST00000431975_ESR1_chr6_152415520_ENST00000456483_length(transcript)=4976nt_BP=249nt GCCCTGGCCTCCGCCTCGGCCTCGCCTCCAGCCCCGGGACGCGGCCCGCCACCGCCGCTGCCGCCAGCCCAGACGCGCCGCCCGCATGCG CCGCGACCATGGAGCGCCCCGAAGCGGGAGGAATTAATTCCAATGAGTGTGAAAATGTATCAAGAAAAAAGAAAATGTCAGAGGAATTTG AAGCCAATACTATGGATTCTCTGGTAGACATGCCATTTGCTACTGTAGATATTCAGGATGACTGTGGAAGAGTGTACACATTTCTGTCCA GCACCCTGAAGTCTCTGGAAGAGAAGGACCATATCCACCGAGTCCTGGACAAGATCACAGACACTTTGATCCACCTGATGGCCAAGGCAG GCCTGACCCTGCAGCAGCAGCACCAGCGGCTGGCCCAGCTCCTCCTCATCCTCTCCCACATCAGGCACATGAGTAACAAAGGCATGGAGC ATCTGTACAGCATGAAGTGCAAGAACGTGGTGCCCCTCTATGACCTGCTGCTGGAGATGCTGGACGCCCACCGCCTACATGCGCCCACTA GCCGTGGAGGGGCATCCGTGGAGGAGACGGACCAAAGCCACTTGGCCACTGCGGGCTCTACTTCATCGCATTCCTTGCAAAAGTATTACA TCACGGGGGAGGCAGAGGGTTTCCCTGCCACGGTCTGAGAGCTCCCTGGCTCCCACACGGTTCAGATAATCCCTGCTGCATTTTACCCTC ATCATGCACCACTTTAGCCAAATTCTGTCTCCTGCATACACTCCGGCATGCATCCAACACCAATGGCTTTCTAGATGAGTGGCCATTCAT TTGCTTGCTCAGTTCTTAGTGGCACATCTTCTGTCTTCTGTTGGGAACAGCCAAAGGGATTCCAAGGCTAAATCTTTGTAACAGCTCTCT TTCCCCCTTGCTATGTTACTAAGCGTGAGGATTCCCGTAGCTCTTCACAGCTGAACTCAGTCTATGGGTTGGGGCTCAGATAACTCTGTG CATTTAAGCTACTTGTAGAGACCCAGGCCTGGAGAGTAGACATTTTGCCTCTGATAAGCACTTTTTAAATGGCTCTAAGAATAAGCCACA GCAAAGAATTTAAAGTGGCTCCTTTAATTGGTGACTTGGAGAAAGCTAGGTCAAGGGTTTATTATAGCACCCTCTTGTATTCCTATGGCA ATGCATCCTTTTATGAAAGTGGTACACCTTAAAGCTTTTATATGACTGTAGCAGAGTATCTGGTGATTGTCAATTCATTCCCCCTATAGG AATACAAGGGGCACACAGGGAAGGCAGATCCCCTAGTTGGCAAGACTATTTTAACTTGATACACTGCAGATTCAGATGTGCTGAAAGCTC TGCCTCTGGCTTTCCGGTCATGGGTTCCAGTTAATTCATGCCTCCCATGGACCTATGGAGAGCAGCAAGTTGATCTTAGTTAAGTCTCCC TATATGAGGGATAAGTTCCTGATTTTTGTTTTTATTTTTGTGTTACAAAAGAAAGCCCTCCCTCCCTGAACTTGCAGTAAGGTCAGCTTC AGGACCTGTTCCAGTGGGCACTGTACTTGGATCTTCCCGGCGTGTGTGTGCCTTACACAGGGGTGAACTGTTCACTGTGGTGATGCATGA TGAGGGTAAATGGTAGTTGAAAGGAGCAGGGGCCCTGGTGTTGCATTTAGCCCTGGGGCATGGAGCTGAACAGTACTTGTGCAGGATTGT TGTGGCTACTAGAGAACAAGAGGGAAAGTAGGGCAGAAACTGGATACAGTTCTGAGGCACAGCCAGACTTGCTCAGGGTGGCCCTGCCAC AGGCTGCAGCTACCTAGGAACATTCCTTGCAGACCCCGCATTGCCCTTTGGGGGTGCCCTGGGATCCCTGGGGTAGTCCAGCTCTTCTTC ATTTCCCAGCGTGGCCCTGGTTGGAAGAAGCAGCTGTCACAGCTGCTGTAGACAGCTGTGTTCCTACAATTGGCCCAGCACCCTGGGGCA CGGGAGAAGGGTGGGGACCGTTGCTGTCACTACTCAGGCTGACTGGGGCCTGGTCAGATTACGTATGCCCTTGGTGGTTTAGAGATAATC CAAAATCAGGGTTTGGTTTGGGGAAGAAAATCCTCCCCCTTCCTCCCCCGCCCCGTTCCCTACCGCCTCCACTCCTGCCAGCTCATTTCC TTCAATTTCCTTTGACCTATAGGCTAAAAAAGAAAGGCTCATTCCAGCCACAGGGCAGCCTTCCCTGGGCCTTTGCTTCTCTAGCACAAT TATGGGTTACTTCCTTTTTCTTAACAAAAAAGAATGTTTGATTTCCTCTGGGTGACCTTATTGTCTGTAATTGAAACCCTATTGAGAGGT GATGTCTGTGTTAGCCAATGACCCAGGTGAGCTGCTCGGGCTTCTCTTGGTATGTCTTGTTTGGAAAAGTGGATTTCATTCATTTCTGAT TGTCCAGTTAAGTGATCACCAAAGGACTGAGAATCTGGGAGGGCAAAAAAAAAAAAAAAGTTTTTATGTGCACTTAAATTTGGGGACAAT TTTATGTATCTGTGTTAAGGATATGTTTAAGAACATAATTCTTTTGTTGCTGTTTGTTTAAGAAGCACCTTAGTTTGTTTAAGAAGCACC TTATATAGTATAATATATATTTTTTTGAAATTACATTGCTTGTTTATCAGACAATTGAATGTAGTAATTCTGTTCTGGATTTAATTTGAC TGGGTTAACATGCAAAAACCAAGGAAAAATATTTAGTTTTTTTTTTTTTTTTTGTATACTTTTCAAGCTACCTTGTCATGTATACAGTCA TTTATGCCTAAAGCCTGGTGATTATTCATTTAAATGAAGATCACATTTCATATCAACTTTTGTATCCACAGTAGACAAAATAGCACTAAT CCAGATGCCTATTGTTGGATACTGAATGACAGACAATCTTATGTAGCAAAGATTATGCCTGAAAAGGAAAATTATTCAGGGCAGCTAATT TTGCTTTTACCAAAATATCAGTAGTAATATTTTTGGACAGTAGCTAATGGGTCAGTGGGTTCTTTTTAATGTTTATACTTAGATTTTCTT TTAAAAAAATTAAAATAAAACAAAAAAAAATTTCTAGGACTAGACGATGTAATACCAGCTAAAGCCAAACAATTATACAGTGGAAGGTTT TACATTATTCATCCAATGTGTTTCTATTCATGTTAAGATACTACTACATTTGAAGTGGGCAGAGAACATCAGATGATTGAAATGTTCGCC CAGGGGTCTCCAGCAACTTTGGAAATCTCTTTGTATTTTTACTTGAAGTGCCACTAATGGACAGCAGATATTTTCTGGCTGATGTTGGTA TTGGGTGTAGGAACATGATTTAAAAAAAAACTCTTGCCTCTGCTTTCCCCCACTCTGAGGCAAGTTAAAATGTAAAAGATGTGATTTATC TGGGGGGCTCAGGTATGGTGGGGAAGTGGATTCAGGAATCTGGGGAATGGCAAATATATTAAGAAGAGTATTGAAAGTATTTGGAGGAAA ATGGTTAATTCTGGGTGTGCACCAGGGTTCAGTAGAGTCCACTTCTGCCCTGGAGACCACAAATCAACTAGCTCCATTTACAGCCATTTC TAAAATGGCAGCTTCAGTTCTAGAGAAGAAAGAACAACATCAGCAGTAAAGTCCATGGAATAGCTAGTGGTCTGTGTTTCTTTTCGCCAT TGCCTAGCTTGCCGTAATGATTCTATAATGCCATCATGCAGCAATTATGAGAGGCTAGGTCATCCAAAGAGAAGACCCTATCAATGTAGG TTGCAAAATCTAACCCCTAAGGAAGTGCAGTCTTTGATTTGATTTCCCTAGTAACCTTGCAGATATGTTTAACCAAGCCATAGCCCATGC CTTTTGAGGGCTGAACAAATAAGGGACTTACTGATAATTTACTTTTGATCACATTAAGGTGTTCTCACCTTGAAATCTTATACACTGAAA TGGCCATTGATTTAGGCCACTGGCTTAGAGTACTCCTTCCCCTGCATGACACTGATTACAAATACTTTCCTATTCATACTTTCCAATTAT GAGATGGACTGTGGGTACTGGGAGTGATCACTAACACCATAGTAATGTCTAATATTCACAGGCAGATCTGCTTGGGGAAGCTAGTTATGT GAAAGGCAAATAGAGTCATACAGTAGCTCAAAAGGCAACCATAATTCTCTTTGGTGCAGGTCTTGGGAGCGTGATCTAGATTACACTGCA CCATTCCCAAGTTAATCCCCTGAAAACTTACTCTCAACTGGAGCAAATGAACTTTGGTCCCAAATATCCATCTTTTCAGTAGCGTTAATT ATGCTCTGTTTCCAACTGCATTTCCTTTCCAATTGAATTAAAGTGTGGCCTCGTTTTTAGTCATTTAAAATTGTTTTCTAAGTAATTGCT GCCTCTATTATGGCACTTCAATTTTGCACTGTCTTTTGAGATTCAAGAAAAATTTCTATTCTTTTTTTTGCATCCAATTGTGCCTGAACT TTTAAAATATGTAAATGCTGCCATGTTCCAAACCCATCGTCAGTGTGTGTGTTTAGAGCTGTGCACCCTAGAAACAACATATTGTCCCAT GAGCAGGTGCCTGAGACACAGACCCCTTTGCATTCACAGAGAGGTCATTGGTTATAGAGACTTGAATTAATAAGTGACATTATGCCAGTT TCTGTTCTCTCACAGGTGATAAACAATGCTTTTTGTGCACTACATACTCTTCAGTGTAGAGCTCTTGTTTTATGGGAAAAGGCTCAAATG CCAAATTGTGTTTGATGGATTAATATGCCCTTTTGCCGATGCATACTATTACTGATGTGACTCGGTTTTGTCGCAGCTTTGCTTTGTTTA ATGAAACACACTTGTAAACCTCTTTTGCACTTTGAAAAAGAATCCAGCGGGATGCTCGAGCACCTGTAAACAATTTTCTCAACCTATTTG >3361_3361_12_AKAP7-ESR1_AKAP7_chr6_131466556_ENST00000431975_ESR1_chr6_152415520_ENST00000456483_length(amino acids)=189AA_BP=51 MERPEAGGINSNECENVSRKKKMSEEFEANTMDSLVDMPFATVDIQDDCGRVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLT LQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLLLEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITG -------------------------------------------------------------- >3361_3361_13_AKAP7-ESR1_AKAP7_chr6_131466556_ENST00000541650_ESR1_chr6_152415520_ENST00000206249_length(transcript)=4899nt_BP=175nt GACGCGCCGCCCGCATGCGCCGCGACCATGGAGCGCCCCGAAGCGGGAATTAATTCCAATGAGTGTGAAAATGTATCAAGAAAAAAGAAA ATGTCAGAGGAATTTGAAGCCAATACTATGGATTCTCTGGTAGACATGCCATTTGCTACTGTAGATATTCAGGATGACTGTGGAAGAGTG TACACATTTCTGTCCAGCACCCTGAAGTCTCTGGAAGAGAAGGACCATATCCACCGAGTCCTGGACAAGATCACAGACACTTTGATCCAC CTGATGGCCAAGGCAGGCCTGACCCTGCAGCAGCAGCACCAGCGGCTGGCCCAGCTCCTCCTCATCCTCTCCCACATCAGGCACATGAGT AACAAAGGCATGGAGCATCTGTACAGCATGAAGTGCAAGAACGTGGTGCCCCTCTATGACCTGCTGCTGGAGATGCTGGACGCCCACCGC CTACATGCGCCCACTAGCCGTGGAGGGGCATCCGTGGAGGAGACGGACCAAAGCCACTTGGCCACTGCGGGCTCTACTTCATCGCATTCC TTGCAAAAGTATTACATCACGGGGGAGGCAGAGGGTTTCCCTGCCACGGTCTGAGAGCTCCCTGGCTCCCACACGGTTCAGATAATCCCT GCTGCATTTTACCCTCATCATGCACCACTTTAGCCAAATTCTGTCTCCTGCATACACTCCGGCATGCATCCAACACCAATGGCTTTCTAG ATGAGTGGCCATTCATTTGCTTGCTCAGTTCTTAGTGGCACATCTTCTGTCTTCTGTTGGGAACAGCCAAAGGGATTCCAAGGCTAAATC TTTGTAACAGCTCTCTTTCCCCCTTGCTATGTTACTAAGCGTGAGGATTCCCGTAGCTCTTCACAGCTGAACTCAGTCTATGGGTTGGGG CTCAGATAACTCTGTGCATTTAAGCTACTTGTAGAGACCCAGGCCTGGAGAGTAGACATTTTGCCTCTGATAAGCACTTTTTAAATGGCT CTAAGAATAAGCCACAGCAAAGAATTTAAAGTGGCTCCTTTAATTGGTGACTTGGAGAAAGCTAGGTCAAGGGTTTATTATAGCACCCTC TTGTATTCCTATGGCAATGCATCCTTTTATGAAAGTGGTACACCTTAAAGCTTTTATATGACTGTAGCAGAGTATCTGGTGATTGTCAAT TCATTCCCCCTATAGGAATACAAGGGGCACACAGGGAAGGCAGATCCCCTAGTTGGCAAGACTATTTTAACTTGATACACTGCAGATTCA GATGTGCTGAAAGCTCTGCCTCTGGCTTTCCGGTCATGGGTTCCAGTTAATTCATGCCTCCCATGGACCTATGGAGAGCAGCAAGTTGAT CTTAGTTAAGTCTCCCTATATGAGGGATAAGTTCCTGATTTTTGTTTTTATTTTTGTGTTACAAAAGAAAGCCCTCCCTCCCTGAACTTG CAGTAAGGTCAGCTTCAGGACCTGTTCCAGTGGGCACTGTACTTGGATCTTCCCGGCGTGTGTGTGCCTTACACAGGGGTGAACTGTTCA CTGTGGTGATGCATGATGAGGGTAAATGGTAGTTGAAAGGAGCAGGGGCCCTGGTGTTGCATTTAGCCCTGGGGCATGGAGCTGAACAGT ACTTGTGCAGGATTGTTGTGGCTACTAGAGAACAAGAGGGAAAGTAGGGCAGAAACTGGATACAGTTCTGAGGCACAGCCAGACTTGCTC AGGGTGGCCCTGCCACAGGCTGCAGCTACCTAGGAACATTCCTTGCAGACCCCGCATTGCCCTTTGGGGGTGCCCTGGGATCCCTGGGGT AGTCCAGCTCTTCTTCATTTCCCAGCGTGGCCCTGGTTGGAAGAAGCAGCTGTCACAGCTGCTGTAGACAGCTGTGTTCCTACAATTGGC CCAGCACCCTGGGGCACGGGAGAAGGGTGGGGACCGTTGCTGTCACTACTCAGGCTGACTGGGGCCTGGTCAGATTACGTATGCCCTTGG TGGTTTAGAGATAATCCAAAATCAGGGTTTGGTTTGGGGAAGAAAATCCTCCCCCTTCCTCCCCCGCCCCGTTCCCTACCGCCTCCACTC CTGCCAGCTCATTTCCTTCAATTTCCTTTGACCTATAGGCTAAAAAAGAAAGGCTCATTCCAGCCACAGGGCAGCCTTCCCTGGGCCTTT GCTTCTCTAGCACAATTATGGGTTACTTCCTTTTTCTTAACAAAAAAGAATGTTTGATTTCCTCTGGGTGACCTTATTGTCTGTAATTGA AACCCTATTGAGAGGTGATGTCTGTGTTAGCCAATGACCCAGGTGAGCTGCTCGGGCTTCTCTTGGTATGTCTTGTTTGGAAAAGTGGAT TTCATTCATTTCTGATTGTCCAGTTAAGTGATCACCAAAGGACTGAGAATCTGGGAGGGCAAAAAAAAAAAAAAAGTTTTTATGTGCACT TAAATTTGGGGACAATTTTATGTATCTGTGTTAAGGATATGTTTAAGAACATAATTCTTTTGTTGCTGTTTGTTTAAGAAGCACCTTAGT TTGTTTAAGAAGCACCTTATATAGTATAATATATATTTTTTTGAAATTACATTGCTTGTTTATCAGACAATTGAATGTAGTAATTCTGTT CTGGATTTAATTTGACTGGGTTAACATGCAAAAACCAAGGAAAAATATTTAGTTTTTTTTTTTTTTTTTGTATACTTTTCAAGCTACCTT GTCATGTATACAGTCATTTATGCCTAAAGCCTGGTGATTATTCATTTAAATGAAGATCACATTTCATATCAACTTTTGTATCCACAGTAG ACAAAATAGCACTAATCCAGATGCCTATTGTTGGATACTGAATGACAGACAATCTTATGTAGCAAAGATTATGCCTGAAAAGGAAAATTA TTCAGGGCAGCTAATTTTGCTTTTACCAAAATATCAGTAGTAATATTTTTGGACAGTAGCTAATGGGTCAGTGGGTTCTTTTTAATGTTT ATACTTAGATTTTCTTTTAAAAAAATTAAAATAAAACAAAAAAAAATTTCTAGGACTAGACGATGTAATACCAGCTAAAGCCAAACAATT ATACAGTGGAAGGTTTTACATTATTCATCCAATGTGTTTCTATTCATGTTAAGATACTACTACATTTGAAGTGGGCAGAGAACATCAGAT GATTGAAATGTTCGCCCAGGGGTCTCCAGCAACTTTGGAAATCTCTTTGTATTTTTACTTGAAGTGCCACTAATGGACAGCAGATATTTT CTGGCTGATGTTGGTATTGGGTGTAGGAACATGATTTAAAAAAAAACTCTTGCCTCTGCTTTCCCCCACTCTGAGGCAAGTTAAAATGTA AAAGATGTGATTTATCTGGGGGGCTCAGGTATGGTGGGGAAGTGGATTCAGGAATCTGGGGAATGGCAAATATATTAAGAAGAGTATTGA AAGTATTTGGAGGAAAATGGTTAATTCTGGGTGTGCACCAGGGTTCAGTAGAGTCCACTTCTGCCCTGGAGACCACAAATCAACTAGCTC CATTTACAGCCATTTCTAAAATGGCAGCTTCAGTTCTAGAGAAGAAAGAACAACATCAGCAGTAAAGTCCATGGAATAGCTAGTGGTCTG TGTTTCTTTTCGCCATTGCCTAGCTTGCCGTAATGATTCTATAATGCCATCATGCAGCAATTATGAGAGGCTAGGTCATCCAAAGAGAAG ACCCTATCAATGTAGGTTGCAAAATCTAACCCCTAAGGAAGTGCAGTCTTTGATTTGATTTCCCTAGTAACCTTGCAGATATGTTTAACC AAGCCATAGCCCATGCCTTTTGAGGGCTGAACAAATAAGGGACTTACTGATAATTTACTTTTGATCACATTAAGGTGTTCTCACCTTGAA ATCTTATACACTGAAATGGCCATTGATTTAGGCCACTGGCTTAGAGTACTCCTTCCCCTGCATGACACTGATTACAAATACTTTCCTATT CATACTTTCCAATTATGAGATGGACTGTGGGTACTGGGAGTGATCACTAACACCATAGTAATGTCTAATATTCACAGGCAGATCTGCTTG GGGAAGCTAGTTATGTGAAAGGCAAATAGAGTCATACAGTAGCTCAAAAGGCAACCATAATTCTCTTTGGTGCAGGTCTTGGGAGCGTGA TCTAGATTACACTGCACCATTCCCAAGTTAATCCCCTGAAAACTTACTCTCAACTGGAGCAAATGAACTTTGGTCCCAAATATCCATCTT TTCAGTAGCGTTAATTATGCTCTGTTTCCAACTGCATTTCCTTTCCAATTGAATTAAAGTGTGGCCTCGTTTTTAGTCATTTAAAATTGT TTTCTAAGTAATTGCTGCCTCTATTATGGCACTTCAATTTTGCACTGTCTTTTGAGATTCAAGAAAAATTTCTATTCTTTTTTTTGCATC CAATTGTGCCTGAACTTTTAAAATATGTAAATGCTGCCATGTTCCAAACCCATCGTCAGTGTGTGTGTTTAGAGCTGTGCACCCTAGAAA CAACATATTGTCCCATGAGCAGGTGCCTGAGACACAGACCCCTTTGCATTCACAGAGAGGTCATTGGTTATAGAGACTTGAATTAATAAG TGACATTATGCCAGTTTCTGTTCTCTCACAGGTGATAAACAATGCTTTTTGTGCACTACATACTCTTCAGTGTAGAGCTCTTGTTTTATG GGAAAAGGCTCAAATGCCAAATTGTGTTTGATGGATTAATATGCCCTTTTGCCGATGCATACTATTACTGATGTGACTCGGTTTTGTCGC AGCTTTGCTTTGTTTAATGAAACACACTTGTAAACCTCTTTTGCACTTTGAAAAAGAATCCAGCGGGATGCTCGAGCACCTGTAAACAAT >3361_3361_13_AKAP7-ESR1_AKAP7_chr6_131466556_ENST00000541650_ESR1_chr6_152415520_ENST00000206249_length(amino acids)=188AA_BP=50 MERPEAGINSNECENVSRKKKMSEEFEANTMDSLVDMPFATVDIQDDCGRVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTL QQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLLLEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITGE -------------------------------------------------------------- >3361_3361_14_AKAP7-ESR1_AKAP7_chr6_131466556_ENST00000541650_ESR1_chr6_152415520_ENST00000338799_length(transcript)=681nt_BP=175nt GACGCGCCGCCCGCATGCGCCGCGACCATGGAGCGCCCCGAAGCGGGAATTAATTCCAATGAGTGTGAAAATGTATCAAGAAAAAAGAAA ATGTCAGAGGAATTTGAAGCCAATACTATGGATTCTCTGGTAGACATGCCATTTGCTACTGTAGATATTCAGGATGACTGTGGAAGAGTG TACACATTTCTGTCCAGCACCCTGAAGTCTCTGGAAGAGAAGGACCATATCCACCGAGTCCTGGACAAGATCACAGACACTTTGATCCAC CTGATGGCCAAGGCAGGCCTGACCCTGCAGCAGCAGCACCAGCGGCTGGCCCAGCTCCTCCTCATCCTCTCCCACATCAGGCACATGAGT AACAAAGGCATGGAGCATCTGTACAGCATGAAGTGCAAGAACGTGGTGCCCCTCTATGACCTGCTGCTGGAGATGCTGGACGCCCACCGC CTACATGCGCCCACTAGCCGTGGAGGGGCATCCGTGGAGGAGACGGACCAAAGCCACTTGGCCACTGCGGGCTCTACTTCATCGCATTCC TTGCAAAAGTATTACATCACGGGGGAGGCAGAGGGTTTCCCTGCCACGGTCTGAGAGCTCCCTGGCTCCCACACGGTTCAGATAATCCCT >3361_3361_14_AKAP7-ESR1_AKAP7_chr6_131466556_ENST00000541650_ESR1_chr6_152415520_ENST00000338799_length(amino acids)=188AA_BP=50 MERPEAGINSNECENVSRKKKMSEEFEANTMDSLVDMPFATVDIQDDCGRVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTL QQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLLLEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITGE -------------------------------------------------------------- >3361_3361_15_AKAP7-ESR1_AKAP7_chr6_131466556_ENST00000541650_ESR1_chr6_152415520_ENST00000406599_length(transcript)=606nt_BP=175nt GACGCGCCGCCCGCATGCGCCGCGACCATGGAGCGCCCCGAAGCGGGAATTAATTCCAATGAGTGTGAAAATGTATCAAGAAAAAAGAAA ATGTCAGAGGAATTTGAAGCCAATACTATGGATTCTCTGGTAGACATGCCATTTGCTACTGTAGATATTCAGGATGACTGTGGAAGAGTG TACACATTTCTGTCCAGCACCCTGAAGTCTCTGGAAGAGAAGGACCATATCCACCGAGTCCTGGACAAGATCACAGACACTTTGATCCAC CTGATGGCCAAGGCAGGCCTGACCCTGCAGCAGCAGCACCAGCGGCTGGCCCAGCTCCTCCTCATCCTCTCCCACATCAGGCACATGAGT AACAAAGGCATGGAGCATCTGTACAGCATGAAGTGCAAGAACGTGGTGCCCCTCTATGACCTGCTGCTGGAGATGCTGGACGCCCACCGC CTACATGCGCCCACTAGCCGTGGAGGGGCATCCGTGGAGGAGACGGACCAAAGCCACTTGGCCACTGCGGGCTCTACTTCATCGCATTCC >3361_3361_15_AKAP7-ESR1_AKAP7_chr6_131466556_ENST00000541650_ESR1_chr6_152415520_ENST00000406599_length(amino acids)=188AA_BP=50 MERPEAGINSNECENVSRKKKMSEEFEANTMDSLVDMPFATVDIQDDCGRVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTL QQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLLLEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITGE -------------------------------------------------------------- >3361_3361_16_AKAP7-ESR1_AKAP7_chr6_131466556_ENST00000541650_ESR1_chr6_152415520_ENST00000440973_length(transcript)=4902nt_BP=175nt GACGCGCCGCCCGCATGCGCCGCGACCATGGAGCGCCCCGAAGCGGGAATTAATTCCAATGAGTGTGAAAATGTATCAAGAAAAAAGAAA ATGTCAGAGGAATTTGAAGCCAATACTATGGATTCTCTGGTAGACATGCCATTTGCTACTGTAGATATTCAGGATGACTGTGGAAGAGTG TACACATTTCTGTCCAGCACCCTGAAGTCTCTGGAAGAGAAGGACCATATCCACCGAGTCCTGGACAAGATCACAGACACTTTGATCCAC CTGATGGCCAAGGCAGGCCTGACCCTGCAGCAGCAGCACCAGCGGCTGGCCCAGCTCCTCCTCATCCTCTCCCACATCAGGCACATGAGT AACAAAGGCATGGAGCATCTGTACAGCATGAAGTGCAAGAACGTGGTGCCCCTCTATGACCTGCTGCTGGAGATGCTGGACGCCCACCGC CTACATGCGCCCACTAGCCGTGGAGGGGCATCCGTGGAGGAGACGGACCAAAGCCACTTGGCCACTGCGGGCTCTACTTCATCGCATTCC TTGCAAAAGTATTACATCACGGGGGAGGCAGAGGGTTTCCCTGCCACGGTCTGAGAGCTCCCTGGCTCCCACACGGTTCAGATAATCCCT GCTGCATTTTACCCTCATCATGCACCACTTTAGCCAAATTCTGTCTCCTGCATACACTCCGGCATGCATCCAACACCAATGGCTTTCTAG ATGAGTGGCCATTCATTTGCTTGCTCAGTTCTTAGTGGCACATCTTCTGTCTTCTGTTGGGAACAGCCAAAGGGATTCCAAGGCTAAATC TTTGTAACAGCTCTCTTTCCCCCTTGCTATGTTACTAAGCGTGAGGATTCCCGTAGCTCTTCACAGCTGAACTCAGTCTATGGGTTGGGG CTCAGATAACTCTGTGCATTTAAGCTACTTGTAGAGACCCAGGCCTGGAGAGTAGACATTTTGCCTCTGATAAGCACTTTTTAAATGGCT CTAAGAATAAGCCACAGCAAAGAATTTAAAGTGGCTCCTTTAATTGGTGACTTGGAGAAAGCTAGGTCAAGGGTTTATTATAGCACCCTC TTGTATTCCTATGGCAATGCATCCTTTTATGAAAGTGGTACACCTTAAAGCTTTTATATGACTGTAGCAGAGTATCTGGTGATTGTCAAT TCATTCCCCCTATAGGAATACAAGGGGCACACAGGGAAGGCAGATCCCCTAGTTGGCAAGACTATTTTAACTTGATACACTGCAGATTCA GATGTGCTGAAAGCTCTGCCTCTGGCTTTCCGGTCATGGGTTCCAGTTAATTCATGCCTCCCATGGACCTATGGAGAGCAGCAAGTTGAT CTTAGTTAAGTCTCCCTATATGAGGGATAAGTTCCTGATTTTTGTTTTTATTTTTGTGTTACAAAAGAAAGCCCTCCCTCCCTGAACTTG CAGTAAGGTCAGCTTCAGGACCTGTTCCAGTGGGCACTGTACTTGGATCTTCCCGGCGTGTGTGTGCCTTACACAGGGGTGAACTGTTCA CTGTGGTGATGCATGATGAGGGTAAATGGTAGTTGAAAGGAGCAGGGGCCCTGGTGTTGCATTTAGCCCTGGGGCATGGAGCTGAACAGT ACTTGTGCAGGATTGTTGTGGCTACTAGAGAACAAGAGGGAAAGTAGGGCAGAAACTGGATACAGTTCTGAGGCACAGCCAGACTTGCTC AGGGTGGCCCTGCCACAGGCTGCAGCTACCTAGGAACATTCCTTGCAGACCCCGCATTGCCCTTTGGGGGTGCCCTGGGATCCCTGGGGT AGTCCAGCTCTTCTTCATTTCCCAGCGTGGCCCTGGTTGGAAGAAGCAGCTGTCACAGCTGCTGTAGACAGCTGTGTTCCTACAATTGGC CCAGCACCCTGGGGCACGGGAGAAGGGTGGGGACCGTTGCTGTCACTACTCAGGCTGACTGGGGCCTGGTCAGATTACGTATGCCCTTGG TGGTTTAGAGATAATCCAAAATCAGGGTTTGGTTTGGGGAAGAAAATCCTCCCCCTTCCTCCCCCGCCCCGTTCCCTACCGCCTCCACTC CTGCCAGCTCATTTCCTTCAATTTCCTTTGACCTATAGGCTAAAAAAGAAAGGCTCATTCCAGCCACAGGGCAGCCTTCCCTGGGCCTTT GCTTCTCTAGCACAATTATGGGTTACTTCCTTTTTCTTAACAAAAAAGAATGTTTGATTTCCTCTGGGTGACCTTATTGTCTGTAATTGA AACCCTATTGAGAGGTGATGTCTGTGTTAGCCAATGACCCAGGTGAGCTGCTCGGGCTTCTCTTGGTATGTCTTGTTTGGAAAAGTGGAT TTCATTCATTTCTGATTGTCCAGTTAAGTGATCACCAAAGGACTGAGAATCTGGGAGGGCAAAAAAAAAAAAAAAGTTTTTATGTGCACT TAAATTTGGGGACAATTTTATGTATCTGTGTTAAGGATATGTTTAAGAACATAATTCTTTTGTTGCTGTTTGTTTAAGAAGCACCTTAGT TTGTTTAAGAAGCACCTTATATAGTATAATATATATTTTTTTGAAATTACATTGCTTGTTTATCAGACAATTGAATGTAGTAATTCTGTT CTGGATTTAATTTGACTGGGTTAACATGCAAAAACCAAGGAAAAATATTTAGTTTTTTTTTTTTTTTTTGTATACTTTTCAAGCTACCTT GTCATGTATACAGTCATTTATGCCTAAAGCCTGGTGATTATTCATTTAAATGAAGATCACATTTCATATCAACTTTTGTATCCACAGTAG ACAAAATAGCACTAATCCAGATGCCTATTGTTGGATACTGAATGACAGACAATCTTATGTAGCAAAGATTATGCCTGAAAAGGAAAATTA TTCAGGGCAGCTAATTTTGCTTTTACCAAAATATCAGTAGTAATATTTTTGGACAGTAGCTAATGGGTCAGTGGGTTCTTTTTAATGTTT ATACTTAGATTTTCTTTTAAAAAAATTAAAATAAAACAAAAAAAAATTTCTAGGACTAGACGATGTAATACCAGCTAAAGCCAAACAATT ATACAGTGGAAGGTTTTACATTATTCATCCAATGTGTTTCTATTCATGTTAAGATACTACTACATTTGAAGTGGGCAGAGAACATCAGAT GATTGAAATGTTCGCCCAGGGGTCTCCAGCAACTTTGGAAATCTCTTTGTATTTTTACTTGAAGTGCCACTAATGGACAGCAGATATTTT CTGGCTGATGTTGGTATTGGGTGTAGGAACATGATTTAAAAAAAAACTCTTGCCTCTGCTTTCCCCCACTCTGAGGCAAGTTAAAATGTA AAAGATGTGATTTATCTGGGGGGCTCAGGTATGGTGGGGAAGTGGATTCAGGAATCTGGGGAATGGCAAATATATTAAGAAGAGTATTGA AAGTATTTGGAGGAAAATGGTTAATTCTGGGTGTGCACCAGGGTTCAGTAGAGTCCACTTCTGCCCTGGAGACCACAAATCAACTAGCTC CATTTACAGCCATTTCTAAAATGGCAGCTTCAGTTCTAGAGAAGAAAGAACAACATCAGCAGTAAAGTCCATGGAATAGCTAGTGGTCTG TGTTTCTTTTCGCCATTGCCTAGCTTGCCGTAATGATTCTATAATGCCATCATGCAGCAATTATGAGAGGCTAGGTCATCCAAAGAGAAG ACCCTATCAATGTAGGTTGCAAAATCTAACCCCTAAGGAAGTGCAGTCTTTGATTTGATTTCCCTAGTAACCTTGCAGATATGTTTAACC AAGCCATAGCCCATGCCTTTTGAGGGCTGAACAAATAAGGGACTTACTGATAATTTACTTTTGATCACATTAAGGTGTTCTCACCTTGAA ATCTTATACACTGAAATGGCCATTGATTTAGGCCACTGGCTTAGAGTACTCCTTCCCCTGCATGACACTGATTACAAATACTTTCCTATT CATACTTTCCAATTATGAGATGGACTGTGGGTACTGGGAGTGATCACTAACACCATAGTAATGTCTAATATTCACAGGCAGATCTGCTTG GGGAAGCTAGTTATGTGAAAGGCAAATAGAGTCATACAGTAGCTCAAAAGGCAACCATAATTCTCTTTGGTGCAGGTCTTGGGAGCGTGA TCTAGATTACACTGCACCATTCCCAAGTTAATCCCCTGAAAACTTACTCTCAACTGGAGCAAATGAACTTTGGTCCCAAATATCCATCTT TTCAGTAGCGTTAATTATGCTCTGTTTCCAACTGCATTTCCTTTCCAATTGAATTAAAGTGTGGCCTCGTTTTTAGTCATTTAAAATTGT TTTCTAAGTAATTGCTGCCTCTATTATGGCACTTCAATTTTGCACTGTCTTTTGAGATTCAAGAAAAATTTCTATTCTTTTTTTTGCATC CAATTGTGCCTGAACTTTTAAAATATGTAAATGCTGCCATGTTCCAAACCCATCGTCAGTGTGTGTGTTTAGAGCTGTGCACCCTAGAAA CAACATATTGTCCCATGAGCAGGTGCCTGAGACACAGACCCCTTTGCATTCACAGAGAGGTCATTGGTTATAGAGACTTGAATTAATAAG TGACATTATGCCAGTTTCTGTTCTCTCACAGGTGATAAACAATGCTTTTTGTGCACTACATACTCTTCAGTGTAGAGCTCTTGTTTTATG GGAAAAGGCTCAAATGCCAAATTGTGTTTGATGGATTAATATGCCCTTTTGCCGATGCATACTATTACTGATGTGACTCGGTTTTGTCGC AGCTTTGCTTTGTTTAATGAAACACACTTGTAAACCTCTTTTGCACTTTGAAAAAGAATCCAGCGGGATGCTCGAGCACCTGTAAACAAT >3361_3361_16_AKAP7-ESR1_AKAP7_chr6_131466556_ENST00000541650_ESR1_chr6_152415520_ENST00000440973_length(amino acids)=188AA_BP=50 MERPEAGINSNECENVSRKKKMSEEFEANTMDSLVDMPFATVDIQDDCGRVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTL QQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLLLEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITGE -------------------------------------------------------------- >3361_3361_17_AKAP7-ESR1_AKAP7_chr6_131466556_ENST00000541650_ESR1_chr6_152415520_ENST00000443427_length(transcript)=4902nt_BP=175nt GACGCGCCGCCCGCATGCGCCGCGACCATGGAGCGCCCCGAAGCGGGAATTAATTCCAATGAGTGTGAAAATGTATCAAGAAAAAAGAAA ATGTCAGAGGAATTTGAAGCCAATACTATGGATTCTCTGGTAGACATGCCATTTGCTACTGTAGATATTCAGGATGACTGTGGAAGAGTG TACACATTTCTGTCCAGCACCCTGAAGTCTCTGGAAGAGAAGGACCATATCCACCGAGTCCTGGACAAGATCACAGACACTTTGATCCAC CTGATGGCCAAGGCAGGCCTGACCCTGCAGCAGCAGCACCAGCGGCTGGCCCAGCTCCTCCTCATCCTCTCCCACATCAGGCACATGAGT AACAAAGGCATGGAGCATCTGTACAGCATGAAGTGCAAGAACGTGGTGCCCCTCTATGACCTGCTGCTGGAGATGCTGGACGCCCACCGC CTACATGCGCCCACTAGCCGTGGAGGGGCATCCGTGGAGGAGACGGACCAAAGCCACTTGGCCACTGCGGGCTCTACTTCATCGCATTCC TTGCAAAAGTATTACATCACGGGGGAGGCAGAGGGTTTCCCTGCCACGGTCTGAGAGCTCCCTGGCTCCCACACGGTTCAGATAATCCCT GCTGCATTTTACCCTCATCATGCACCACTTTAGCCAAATTCTGTCTCCTGCATACACTCCGGCATGCATCCAACACCAATGGCTTTCTAG ATGAGTGGCCATTCATTTGCTTGCTCAGTTCTTAGTGGCACATCTTCTGTCTTCTGTTGGGAACAGCCAAAGGGATTCCAAGGCTAAATC TTTGTAACAGCTCTCTTTCCCCCTTGCTATGTTACTAAGCGTGAGGATTCCCGTAGCTCTTCACAGCTGAACTCAGTCTATGGGTTGGGG CTCAGATAACTCTGTGCATTTAAGCTACTTGTAGAGACCCAGGCCTGGAGAGTAGACATTTTGCCTCTGATAAGCACTTTTTAAATGGCT CTAAGAATAAGCCACAGCAAAGAATTTAAAGTGGCTCCTTTAATTGGTGACTTGGAGAAAGCTAGGTCAAGGGTTTATTATAGCACCCTC TTGTATTCCTATGGCAATGCATCCTTTTATGAAAGTGGTACACCTTAAAGCTTTTATATGACTGTAGCAGAGTATCTGGTGATTGTCAAT TCATTCCCCCTATAGGAATACAAGGGGCACACAGGGAAGGCAGATCCCCTAGTTGGCAAGACTATTTTAACTTGATACACTGCAGATTCA GATGTGCTGAAAGCTCTGCCTCTGGCTTTCCGGTCATGGGTTCCAGTTAATTCATGCCTCCCATGGACCTATGGAGAGCAGCAAGTTGAT CTTAGTTAAGTCTCCCTATATGAGGGATAAGTTCCTGATTTTTGTTTTTATTTTTGTGTTACAAAAGAAAGCCCTCCCTCCCTGAACTTG CAGTAAGGTCAGCTTCAGGACCTGTTCCAGTGGGCACTGTACTTGGATCTTCCCGGCGTGTGTGTGCCTTACACAGGGGTGAACTGTTCA CTGTGGTGATGCATGATGAGGGTAAATGGTAGTTGAAAGGAGCAGGGGCCCTGGTGTTGCATTTAGCCCTGGGGCATGGAGCTGAACAGT ACTTGTGCAGGATTGTTGTGGCTACTAGAGAACAAGAGGGAAAGTAGGGCAGAAACTGGATACAGTTCTGAGGCACAGCCAGACTTGCTC AGGGTGGCCCTGCCACAGGCTGCAGCTACCTAGGAACATTCCTTGCAGACCCCGCATTGCCCTTTGGGGGTGCCCTGGGATCCCTGGGGT AGTCCAGCTCTTCTTCATTTCCCAGCGTGGCCCTGGTTGGAAGAAGCAGCTGTCACAGCTGCTGTAGACAGCTGTGTTCCTACAATTGGC CCAGCACCCTGGGGCACGGGAGAAGGGTGGGGACCGTTGCTGTCACTACTCAGGCTGACTGGGGCCTGGTCAGATTACGTATGCCCTTGG TGGTTTAGAGATAATCCAAAATCAGGGTTTGGTTTGGGGAAGAAAATCCTCCCCCTTCCTCCCCCGCCCCGTTCCCTACCGCCTCCACTC CTGCCAGCTCATTTCCTTCAATTTCCTTTGACCTATAGGCTAAAAAAGAAAGGCTCATTCCAGCCACAGGGCAGCCTTCCCTGGGCCTTT GCTTCTCTAGCACAATTATGGGTTACTTCCTTTTTCTTAACAAAAAAGAATGTTTGATTTCCTCTGGGTGACCTTATTGTCTGTAATTGA AACCCTATTGAGAGGTGATGTCTGTGTTAGCCAATGACCCAGGTGAGCTGCTCGGGCTTCTCTTGGTATGTCTTGTTTGGAAAAGTGGAT TTCATTCATTTCTGATTGTCCAGTTAAGTGATCACCAAAGGACTGAGAATCTGGGAGGGCAAAAAAAAAAAAAAAGTTTTTATGTGCACT TAAATTTGGGGACAATTTTATGTATCTGTGTTAAGGATATGTTTAAGAACATAATTCTTTTGTTGCTGTTTGTTTAAGAAGCACCTTAGT TTGTTTAAGAAGCACCTTATATAGTATAATATATATTTTTTTGAAATTACATTGCTTGTTTATCAGACAATTGAATGTAGTAATTCTGTT CTGGATTTAATTTGACTGGGTTAACATGCAAAAACCAAGGAAAAATATTTAGTTTTTTTTTTTTTTTTTGTATACTTTTCAAGCTACCTT GTCATGTATACAGTCATTTATGCCTAAAGCCTGGTGATTATTCATTTAAATGAAGATCACATTTCATATCAACTTTTGTATCCACAGTAG ACAAAATAGCACTAATCCAGATGCCTATTGTTGGATACTGAATGACAGACAATCTTATGTAGCAAAGATTATGCCTGAAAAGGAAAATTA TTCAGGGCAGCTAATTTTGCTTTTACCAAAATATCAGTAGTAATATTTTTGGACAGTAGCTAATGGGTCAGTGGGTTCTTTTTAATGTTT ATACTTAGATTTTCTTTTAAAAAAATTAAAATAAAACAAAAAAAAATTTCTAGGACTAGACGATGTAATACCAGCTAAAGCCAAACAATT ATACAGTGGAAGGTTTTACATTATTCATCCAATGTGTTTCTATTCATGTTAAGATACTACTACATTTGAAGTGGGCAGAGAACATCAGAT GATTGAAATGTTCGCCCAGGGGTCTCCAGCAACTTTGGAAATCTCTTTGTATTTTTACTTGAAGTGCCACTAATGGACAGCAGATATTTT CTGGCTGATGTTGGTATTGGGTGTAGGAACATGATTTAAAAAAAAACTCTTGCCTCTGCTTTCCCCCACTCTGAGGCAAGTTAAAATGTA AAAGATGTGATTTATCTGGGGGGCTCAGGTATGGTGGGGAAGTGGATTCAGGAATCTGGGGAATGGCAAATATATTAAGAAGAGTATTGA AAGTATTTGGAGGAAAATGGTTAATTCTGGGTGTGCACCAGGGTTCAGTAGAGTCCACTTCTGCCCTGGAGACCACAAATCAACTAGCTC CATTTACAGCCATTTCTAAAATGGCAGCTTCAGTTCTAGAGAAGAAAGAACAACATCAGCAGTAAAGTCCATGGAATAGCTAGTGGTCTG TGTTTCTTTTCGCCATTGCCTAGCTTGCCGTAATGATTCTATAATGCCATCATGCAGCAATTATGAGAGGCTAGGTCATCCAAAGAGAAG ACCCTATCAATGTAGGTTGCAAAATCTAACCCCTAAGGAAGTGCAGTCTTTGATTTGATTTCCCTAGTAACCTTGCAGATATGTTTAACC AAGCCATAGCCCATGCCTTTTGAGGGCTGAACAAATAAGGGACTTACTGATAATTTACTTTTGATCACATTAAGGTGTTCTCACCTTGAA ATCTTATACACTGAAATGGCCATTGATTTAGGCCACTGGCTTAGAGTACTCCTTCCCCTGCATGACACTGATTACAAATACTTTCCTATT CATACTTTCCAATTATGAGATGGACTGTGGGTACTGGGAGTGATCACTAACACCATAGTAATGTCTAATATTCACAGGCAGATCTGCTTG GGGAAGCTAGTTATGTGAAAGGCAAATAGAGTCATACAGTAGCTCAAAAGGCAACCATAATTCTCTTTGGTGCAGGTCTTGGGAGCGTGA TCTAGATTACACTGCACCATTCCCAAGTTAATCCCCTGAAAACTTACTCTCAACTGGAGCAAATGAACTTTGGTCCCAAATATCCATCTT TTCAGTAGCGTTAATTATGCTCTGTTTCCAACTGCATTTCCTTTCCAATTGAATTAAAGTGTGGCCTCGTTTTTAGTCATTTAAAATTGT TTTCTAAGTAATTGCTGCCTCTATTATGGCACTTCAATTTTGCACTGTCTTTTGAGATTCAAGAAAAATTTCTATTCTTTTTTTTGCATC CAATTGTGCCTGAACTTTTAAAATATGTAAATGCTGCCATGTTCCAAACCCATCGTCAGTGTGTGTGTTTAGAGCTGTGCACCCTAGAAA CAACATATTGTCCCATGAGCAGGTGCCTGAGACACAGACCCCTTTGCATTCACAGAGAGGTCATTGGTTATAGAGACTTGAATTAATAAG TGACATTATGCCAGTTTCTGTTCTCTCACAGGTGATAAACAATGCTTTTTGTGCACTACATACTCTTCAGTGTAGAGCTCTTGTTTTATG GGAAAAGGCTCAAATGCCAAATTGTGTTTGATGGATTAATATGCCCTTTTGCCGATGCATACTATTACTGATGTGACTCGGTTTTGTCGC AGCTTTGCTTTGTTTAATGAAACACACTTGTAAACCTCTTTTGCACTTTGAAAAAGAATCCAGCGGGATGCTCGAGCACCTGTAAACAAT >3361_3361_17_AKAP7-ESR1_AKAP7_chr6_131466556_ENST00000541650_ESR1_chr6_152415520_ENST00000443427_length(amino acids)=188AA_BP=50 MERPEAGINSNECENVSRKKKMSEEFEANTMDSLVDMPFATVDIQDDCGRVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTL QQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLLLEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITGE -------------------------------------------------------------- >3361_3361_18_AKAP7-ESR1_AKAP7_chr6_131466556_ENST00000541650_ESR1_chr6_152415520_ENST00000456483_length(transcript)=4902nt_BP=175nt GACGCGCCGCCCGCATGCGCCGCGACCATGGAGCGCCCCGAAGCGGGAATTAATTCCAATGAGTGTGAAAATGTATCAAGAAAAAAGAAA ATGTCAGAGGAATTTGAAGCCAATACTATGGATTCTCTGGTAGACATGCCATTTGCTACTGTAGATATTCAGGATGACTGTGGAAGAGTG TACACATTTCTGTCCAGCACCCTGAAGTCTCTGGAAGAGAAGGACCATATCCACCGAGTCCTGGACAAGATCACAGACACTTTGATCCAC CTGATGGCCAAGGCAGGCCTGACCCTGCAGCAGCAGCACCAGCGGCTGGCCCAGCTCCTCCTCATCCTCTCCCACATCAGGCACATGAGT AACAAAGGCATGGAGCATCTGTACAGCATGAAGTGCAAGAACGTGGTGCCCCTCTATGACCTGCTGCTGGAGATGCTGGACGCCCACCGC CTACATGCGCCCACTAGCCGTGGAGGGGCATCCGTGGAGGAGACGGACCAAAGCCACTTGGCCACTGCGGGCTCTACTTCATCGCATTCC TTGCAAAAGTATTACATCACGGGGGAGGCAGAGGGTTTCCCTGCCACGGTCTGAGAGCTCCCTGGCTCCCACACGGTTCAGATAATCCCT GCTGCATTTTACCCTCATCATGCACCACTTTAGCCAAATTCTGTCTCCTGCATACACTCCGGCATGCATCCAACACCAATGGCTTTCTAG ATGAGTGGCCATTCATTTGCTTGCTCAGTTCTTAGTGGCACATCTTCTGTCTTCTGTTGGGAACAGCCAAAGGGATTCCAAGGCTAAATC TTTGTAACAGCTCTCTTTCCCCCTTGCTATGTTACTAAGCGTGAGGATTCCCGTAGCTCTTCACAGCTGAACTCAGTCTATGGGTTGGGG CTCAGATAACTCTGTGCATTTAAGCTACTTGTAGAGACCCAGGCCTGGAGAGTAGACATTTTGCCTCTGATAAGCACTTTTTAAATGGCT CTAAGAATAAGCCACAGCAAAGAATTTAAAGTGGCTCCTTTAATTGGTGACTTGGAGAAAGCTAGGTCAAGGGTTTATTATAGCACCCTC TTGTATTCCTATGGCAATGCATCCTTTTATGAAAGTGGTACACCTTAAAGCTTTTATATGACTGTAGCAGAGTATCTGGTGATTGTCAAT TCATTCCCCCTATAGGAATACAAGGGGCACACAGGGAAGGCAGATCCCCTAGTTGGCAAGACTATTTTAACTTGATACACTGCAGATTCA GATGTGCTGAAAGCTCTGCCTCTGGCTTTCCGGTCATGGGTTCCAGTTAATTCATGCCTCCCATGGACCTATGGAGAGCAGCAAGTTGAT CTTAGTTAAGTCTCCCTATATGAGGGATAAGTTCCTGATTTTTGTTTTTATTTTTGTGTTACAAAAGAAAGCCCTCCCTCCCTGAACTTG CAGTAAGGTCAGCTTCAGGACCTGTTCCAGTGGGCACTGTACTTGGATCTTCCCGGCGTGTGTGTGCCTTACACAGGGGTGAACTGTTCA CTGTGGTGATGCATGATGAGGGTAAATGGTAGTTGAAAGGAGCAGGGGCCCTGGTGTTGCATTTAGCCCTGGGGCATGGAGCTGAACAGT ACTTGTGCAGGATTGTTGTGGCTACTAGAGAACAAGAGGGAAAGTAGGGCAGAAACTGGATACAGTTCTGAGGCACAGCCAGACTTGCTC AGGGTGGCCCTGCCACAGGCTGCAGCTACCTAGGAACATTCCTTGCAGACCCCGCATTGCCCTTTGGGGGTGCCCTGGGATCCCTGGGGT AGTCCAGCTCTTCTTCATTTCCCAGCGTGGCCCTGGTTGGAAGAAGCAGCTGTCACAGCTGCTGTAGACAGCTGTGTTCCTACAATTGGC CCAGCACCCTGGGGCACGGGAGAAGGGTGGGGACCGTTGCTGTCACTACTCAGGCTGACTGGGGCCTGGTCAGATTACGTATGCCCTTGG TGGTTTAGAGATAATCCAAAATCAGGGTTTGGTTTGGGGAAGAAAATCCTCCCCCTTCCTCCCCCGCCCCGTTCCCTACCGCCTCCACTC CTGCCAGCTCATTTCCTTCAATTTCCTTTGACCTATAGGCTAAAAAAGAAAGGCTCATTCCAGCCACAGGGCAGCCTTCCCTGGGCCTTT GCTTCTCTAGCACAATTATGGGTTACTTCCTTTTTCTTAACAAAAAAGAATGTTTGATTTCCTCTGGGTGACCTTATTGTCTGTAATTGA AACCCTATTGAGAGGTGATGTCTGTGTTAGCCAATGACCCAGGTGAGCTGCTCGGGCTTCTCTTGGTATGTCTTGTTTGGAAAAGTGGAT TTCATTCATTTCTGATTGTCCAGTTAAGTGATCACCAAAGGACTGAGAATCTGGGAGGGCAAAAAAAAAAAAAAAGTTTTTATGTGCACT TAAATTTGGGGACAATTTTATGTATCTGTGTTAAGGATATGTTTAAGAACATAATTCTTTTGTTGCTGTTTGTTTAAGAAGCACCTTAGT TTGTTTAAGAAGCACCTTATATAGTATAATATATATTTTTTTGAAATTACATTGCTTGTTTATCAGACAATTGAATGTAGTAATTCTGTT CTGGATTTAATTTGACTGGGTTAACATGCAAAAACCAAGGAAAAATATTTAGTTTTTTTTTTTTTTTTTGTATACTTTTCAAGCTACCTT GTCATGTATACAGTCATTTATGCCTAAAGCCTGGTGATTATTCATTTAAATGAAGATCACATTTCATATCAACTTTTGTATCCACAGTAG ACAAAATAGCACTAATCCAGATGCCTATTGTTGGATACTGAATGACAGACAATCTTATGTAGCAAAGATTATGCCTGAAAAGGAAAATTA TTCAGGGCAGCTAATTTTGCTTTTACCAAAATATCAGTAGTAATATTTTTGGACAGTAGCTAATGGGTCAGTGGGTTCTTTTTAATGTTT ATACTTAGATTTTCTTTTAAAAAAATTAAAATAAAACAAAAAAAAATTTCTAGGACTAGACGATGTAATACCAGCTAAAGCCAAACAATT ATACAGTGGAAGGTTTTACATTATTCATCCAATGTGTTTCTATTCATGTTAAGATACTACTACATTTGAAGTGGGCAGAGAACATCAGAT GATTGAAATGTTCGCCCAGGGGTCTCCAGCAACTTTGGAAATCTCTTTGTATTTTTACTTGAAGTGCCACTAATGGACAGCAGATATTTT CTGGCTGATGTTGGTATTGGGTGTAGGAACATGATTTAAAAAAAAACTCTTGCCTCTGCTTTCCCCCACTCTGAGGCAAGTTAAAATGTA AAAGATGTGATTTATCTGGGGGGCTCAGGTATGGTGGGGAAGTGGATTCAGGAATCTGGGGAATGGCAAATATATTAAGAAGAGTATTGA AAGTATTTGGAGGAAAATGGTTAATTCTGGGTGTGCACCAGGGTTCAGTAGAGTCCACTTCTGCCCTGGAGACCACAAATCAACTAGCTC CATTTACAGCCATTTCTAAAATGGCAGCTTCAGTTCTAGAGAAGAAAGAACAACATCAGCAGTAAAGTCCATGGAATAGCTAGTGGTCTG TGTTTCTTTTCGCCATTGCCTAGCTTGCCGTAATGATTCTATAATGCCATCATGCAGCAATTATGAGAGGCTAGGTCATCCAAAGAGAAG ACCCTATCAATGTAGGTTGCAAAATCTAACCCCTAAGGAAGTGCAGTCTTTGATTTGATTTCCCTAGTAACCTTGCAGATATGTTTAACC AAGCCATAGCCCATGCCTTTTGAGGGCTGAACAAATAAGGGACTTACTGATAATTTACTTTTGATCACATTAAGGTGTTCTCACCTTGAA ATCTTATACACTGAAATGGCCATTGATTTAGGCCACTGGCTTAGAGTACTCCTTCCCCTGCATGACACTGATTACAAATACTTTCCTATT CATACTTTCCAATTATGAGATGGACTGTGGGTACTGGGAGTGATCACTAACACCATAGTAATGTCTAATATTCACAGGCAGATCTGCTTG GGGAAGCTAGTTATGTGAAAGGCAAATAGAGTCATACAGTAGCTCAAAAGGCAACCATAATTCTCTTTGGTGCAGGTCTTGGGAGCGTGA TCTAGATTACACTGCACCATTCCCAAGTTAATCCCCTGAAAACTTACTCTCAACTGGAGCAAATGAACTTTGGTCCCAAATATCCATCTT TTCAGTAGCGTTAATTATGCTCTGTTTCCAACTGCATTTCCTTTCCAATTGAATTAAAGTGTGGCCTCGTTTTTAGTCATTTAAAATTGT TTTCTAAGTAATTGCTGCCTCTATTATGGCACTTCAATTTTGCACTGTCTTTTGAGATTCAAGAAAAATTTCTATTCTTTTTTTTGCATC CAATTGTGCCTGAACTTTTAAAATATGTAAATGCTGCCATGTTCCAAACCCATCGTCAGTGTGTGTGTTTAGAGCTGTGCACCCTAGAAA CAACATATTGTCCCATGAGCAGGTGCCTGAGACACAGACCCCTTTGCATTCACAGAGAGGTCATTGGTTATAGAGACTTGAATTAATAAG TGACATTATGCCAGTTTCTGTTCTCTCACAGGTGATAAACAATGCTTTTTGTGCACTACATACTCTTCAGTGTAGAGCTCTTGTTTTATG GGAAAAGGCTCAAATGCCAAATTGTGTTTGATGGATTAATATGCCCTTTTGCCGATGCATACTATTACTGATGTGACTCGGTTTTGTCGC AGCTTTGCTTTGTTTAATGAAACACACTTGTAAACCTCTTTTGCACTTTGAAAAAGAATCCAGCGGGATGCTCGAGCACCTGTAAACAAT >3361_3361_18_AKAP7-ESR1_AKAP7_chr6_131466556_ENST00000541650_ESR1_chr6_152415520_ENST00000456483_length(amino acids)=188AA_BP=50 MERPEAGINSNECENVSRKKKMSEEFEANTMDSLVDMPFATVDIQDDCGRVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTL QQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLLLEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITGE -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for AKAP7-ESR1 |
Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
Hgene | Hgene's interactors | Tgene | Tgene's interactors |
- Retained PPIs in in-frame fusion. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
- Lost PPIs in in-frame fusion. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
Tgene | ESR1 | chr6:131466556 | chr6:152415520 | ENST00000206249 | 5 | 8 | 262_595 | 456.3333333333333 | 596.0 | AKAP13 | |
Tgene | ESR1 | chr6:131466556 | chr6:152415520 | ENST00000338799 | 6 | 9 | 262_595 | 456.3333333333333 | 596.0 | AKAP13 | |
Tgene | ESR1 | chr6:131466556 | chr6:152415520 | ENST00000440973 | 7 | 10 | 262_595 | 456.3333333333333 | 596.0 | AKAP13 | |
Tgene | ESR1 | chr6:131466556 | chr6:152415520 | ENST00000443427 | 6 | 9 | 262_595 | 456.3333333333333 | 596.0 | AKAP13 | |
Tgene | ESR1 | chr6:131466556 | chr6:152415520 | ENST00000456483 | 5 | 8 | 262_595 | 344.3333333333333 | 484.0 | AKAP13 | |
Tgene | ESR1 | chr6:131466556 | chr6:152415520 | ENST00000206249 | 5 | 8 | 35_174 | 456.3333333333333 | 596.0 | DDX5%3B self-association | |
Tgene | ESR1 | chr6:131466556 | chr6:152415520 | ENST00000338799 | 6 | 9 | 35_174 | 456.3333333333333 | 596.0 | DDX5%3B self-association | |
Tgene | ESR1 | chr6:131466556 | chr6:152415520 | ENST00000440973 | 7 | 10 | 35_174 | 456.3333333333333 | 596.0 | DDX5%3B self-association | |
Tgene | ESR1 | chr6:131466556 | chr6:152415520 | ENST00000443427 | 6 | 9 | 35_174 | 456.3333333333333 | 596.0 | DDX5%3B self-association | |
Tgene | ESR1 | chr6:131466556 | chr6:152415520 | ENST00000456483 | 5 | 8 | 35_174 | 344.3333333333333 | 484.0 | DDX5%3B self-association |
- Retained PPIs, but lost function due to frame-shift fusion. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for AKAP7-ESR1 |
Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for AKAP7-ESR1 |
Diseases associated with fusion partners. (DisGeNet 4.0) |
Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
Hgene | AKAP7 | C0013146 | Drug abuse | 1 | CTD_human |
Hgene | AKAP7 | C0013170 | Drug habituation | 1 | CTD_human |
Hgene | AKAP7 | C0013222 | Drug Use Disorders | 1 | CTD_human |
Hgene | AKAP7 | C0029231 | Organic Mental Disorders, Substance-Induced | 1 | CTD_human |
Hgene | AKAP7 | C0038580 | Substance Dependence | 1 | CTD_human |
Hgene | AKAP7 | C0038586 | Substance Use Disorders | 1 | CTD_human |
Hgene | AKAP7 | C0236969 | Substance-Related Disorders | 1 | CTD_human |
Hgene | AKAP7 | C0740858 | Substance abuse problem | 1 | CTD_human |
Hgene | AKAP7 | C1510472 | Drug Dependence | 1 | CTD_human |
Hgene | AKAP7 | C4316881 | Prescription Drug Abuse | 1 | CTD_human |
Tgene | C0006142 | Malignant neoplasm of breast | 14 | CGI;CTD_human;GENOMICS_ENGLAND;UNIPROT | |
Tgene | C0678222 | Breast Carcinoma | 14 | CGI;CTD_human | |
Tgene | C1257931 | Mammary Neoplasms, Human | 14 | CTD_human | |
Tgene | C1458155 | Mammary Neoplasms | 14 | CTD_human | |
Tgene | C4704874 | Mammary Carcinoma, Human | 14 | CTD_human | |
Tgene | C0005586 | Bipolar Disorder | 5 | PSYGENET | |
Tgene | C0011570 | Mental Depression | 5 | PSYGENET | |
Tgene | C0011581 | Depressive disorder | 5 | PSYGENET | |
Tgene | C0036341 | Schizophrenia | 5 | PSYGENET | |
Tgene | C0525045 | Mood Disorders | 4 | PSYGENET | |
Tgene | C3809250 | ESTROGEN RESISTANCE | 3 | GENOMICS_ENGLAND;ORPHANET;UNIPROT | |
Tgene | C0001418 | Adenocarcinoma | 2 | CTD_human | |
Tgene | C0007097 | Carcinoma | 2 | CTD_human | |
Tgene | C0007621 | Neoplastic Cell Transformation | 2 | CTD_human | |
Tgene | C0010054 | Coronary Arteriosclerosis | 2 | CTD_human | |
Tgene | C0021364 | Male infertility | 2 | CTD_human | |
Tgene | C0024121 | Lung Neoplasms | 2 | CTD_human | |
Tgene | C0024667 | Animal Mammary Neoplasms | 2 | CTD_human | |
Tgene | C0025500 | Mesothelioma | 2 | CTD_human | |
Tgene | C0027626 | Neoplasm Invasiveness | 2 | CTD_human | |
Tgene | C0033578 | Prostatic Neoplasms | 2 | CTD_human | |
Tgene | C0205641 | Adenocarcinoma, Basal Cell | 2 | CTD_human | |
Tgene | C0205642 | Adenocarcinoma, Oxyphilic | 2 | CTD_human | |
Tgene | C0205643 | Carcinoma, Cribriform | 2 | CTD_human | |
Tgene | C0205644 | Carcinoma, Granular Cell | 2 | CTD_human | |
Tgene | C0205645 | Adenocarcinoma, Tubular | 2 | CTD_human | |
Tgene | C0205696 | Anaplastic carcinoma | 2 | CTD_human | |
Tgene | C0205697 | Carcinoma, Spindle-Cell | 2 | CTD_human | |
Tgene | C0205698 | Undifferentiated carcinoma | 2 | CTD_human | |
Tgene | C0205699 | Carcinomatosis | 2 | CTD_human | |
Tgene | C0242379 | Malignant neoplasm of lung | 2 | CTD_human | |
Tgene | C0376358 | Malignant neoplasm of prostate | 2 | CTD_human | |
Tgene | C0848676 | Subfertility, Male | 2 | CTD_human | |
Tgene | C0917731 | Male sterility | 2 | CTD_human | |
Tgene | C1257925 | Mammary Carcinoma, Animal | 2 | CTD_human | |
Tgene | C1956346 | Coronary Artery Disease | 2 | CTD_human | |
Tgene | C2239176 | Liver carcinoma | 2 | CTD_human | |
Tgene | C0002395 | Alzheimer's Disease | 1 | CTD_human | |
Tgene | C0004114 | Astrocytoma | 1 | CTD_human | |
Tgene | C0004153 | Atherosclerosis | 1 | CTD_human | |
Tgene | C0005684 | Malignant neoplasm of urinary bladder | 1 | CTD_human | |
Tgene | C0005695 | Bladder Neoplasm | 1 | CTD_human | |
Tgene | C0005940 | Bone Diseases | 1 | CTD_human | |
Tgene | C0005944 | Metabolic Bone Disorder | 1 | CTD_human | |
Tgene | C0007852 | Cervical Migraine Syndrome | 1 | CTD_human | |
Tgene | C0011265 | Presenile dementia | 1 | CTD_human | |
Tgene | C0014170 | Endometrial Neoplasms | 1 | CTD_human | |
Tgene | C0017658 | Glomerulonephritis | 1 | CTD_human | |
Tgene | C0018984 | Hemicrania migraine | 1 | CTD_human | |
Tgene | C0021361 | Female infertility | 1 | CTD_human | |
Tgene | C0023267 | Fibroid Tumor | 1 | CTD_human | |
Tgene | C0023418 | leukemia | 1 | CTD_human | |
Tgene | C0023903 | Liver neoplasms | 1 | CTD_human | |
Tgene | C0024668 | Mammary Neoplasms, Experimental | 1 | CTD_human | |
Tgene | C0024809 | Marijuana Abuse | 1 | PSYGENET | |
Tgene | C0026858 | Musculoskeletal Pain | 1 | CTD_human | |
Tgene | C0027051 | Myocardial Infarction | 1 | CTD_human | |
Tgene | C0027627 | Neoplasm Metastasis | 1 | CTD_human | |
Tgene | C0027643 | Neoplasm Recurrence, Local | 1 | CTD_human | |
Tgene | C0027819 | Neuroblastoma | 1 | CTD_human | |
Tgene | C0028754 | Obesity | 1 | CTD_human | |
Tgene | C0028960 | Oligospermia | 1 | CTD_human | |
Tgene | C0029453 | Osteopenia | 1 | CTD_human | |
Tgene | C0033937 | Psychoses, Drug | 1 | CTD_human | |
Tgene | C0033941 | Psychoses, Substance-Induced | 1 | CTD_human | |
Tgene | C0036939 | Shared Paranoid Disorder | 1 | PSYGENET | |
Tgene | C0038279 | Sterility, Postpartum | 1 | CTD_human | |
Tgene | C0042133 | Uterine Fibroids | 1 | CTD_human | |
Tgene | C0149931 | Migraine Disorders | 1 | CTD_human | |
Tgene | C0205768 | Subependymal Giant Cell Astrocytoma | 1 | CTD_human | |
Tgene | C0235874 | Disease Exacerbation | 1 | CTD_human | |
Tgene | C0270858 | Abdominal Migraine | 1 | CTD_human | |
Tgene | C0276496 | Familial Alzheimer Disease (FAD) | 1 | CTD_human | |
Tgene | C0280783 | Juvenile Pilocytic Astrocytoma | 1 | CTD_human | |
Tgene | C0280785 | Diffuse Astrocytoma | 1 | CTD_human | |
Tgene | C0282612 | Prostatic Intraepithelial Neoplasias | 1 | CTD_human | |
Tgene | C0334579 | Anaplastic astrocytoma | 1 | CTD_human | |
Tgene | C0334580 | Protoplasmic astrocytoma | 1 | CTD_human | |
Tgene | C0334581 | Gemistocytic astrocytoma | 1 | CTD_human | |
Tgene | C0334582 | Fibrillary Astrocytoma | 1 | CTD_human | |
Tgene | C0334583 | Pilocytic Astrocytoma | 1 | CTD_human | |
Tgene | C0338070 | Childhood Cerebral Astrocytoma | 1 | CTD_human | |
Tgene | C0338489 | Status Migrainosus | 1 | CTD_human | |
Tgene | C0341869 | Subfertility, Female | 1 | CTD_human | |
Tgene | C0345904 | Malignant neoplasm of liver | 1 | CTD_human | |
Tgene | C0476089 | Endometrial Carcinoma | 1 | CGI;CTD_human | |
Tgene | C0494463 | Alzheimer Disease, Late Onset | 1 | CTD_human | |
Tgene | C0521664 | Acute Confusional Migraine | 1 | CTD_human | |
Tgene | C0546126 | Acute Confusional Senile Dementia | 1 | CTD_human | |
Tgene | C0547065 | Mixed oligoastrocytoma | 1 | CTD_human | |
Tgene | C0700438 | Sick Headaches | 1 | CTD_human | |
Tgene | C0750900 | Alzheimer's Disease, Focal Onset | 1 | CTD_human | |
Tgene | C0750901 | Alzheimer Disease, Early Onset | 1 | CTD_human | |
Tgene | C0750935 | Cerebral Astrocytoma | 1 | CTD_human | |
Tgene | C0750936 | Intracranial Astrocytoma | 1 | CTD_human | |
Tgene | C0917730 | Female sterility | 1 | CTD_human | |
Tgene | C1563937 | Atherogenesis | 1 | CTD_human | |
Tgene | C1704230 | Grade I Astrocytoma | 1 | CTD_human | |
Tgene | C1704377 | Bright Disease | 1 | CTD_human | |
Tgene | C1720887 | Female Urogenital Diseases | 1 | CTD_human | |
Tgene | C1800706 | Idiopathic Pulmonary Fibrosis | 1 | CTD_human | |
Tgene | C4721508 | Hamman-Rich Disease | 1 | CTD_human | |
Tgene | C4721509 | Usual Interstitial Pneumonia | 1 | CTD_human | |
Tgene | C4721952 | Familial Idiopathic Pulmonary Fibrosis | 1 | CTD_human |