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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:NOS1AP-ASH1L (FusionGDB2 ID:HG9722TG55870)

Fusion Gene Summary for NOS1AP-ASH1L

check button Fusion gene summary
Fusion gene informationFusion gene name: NOS1AP-ASH1L
Fusion gene ID: hg9722tg55870
HgeneTgene
Gene symbol

NOS1AP

ASH1L

Gene ID

9722

55870

Gene namenitric oxide synthase 1 adaptor proteinASH1 like histone lysine methyltransferase
Synonyms6330408P19Rik|CAPONASH1|ASH1L1|KMT2H|MRD52
Cytomap('NOS1AP')('ASH1L')

1q23.3

1q22

Type of geneprotein-codingprotein-coding
Descriptioncarboxyl-terminal PDZ ligand of neuronal nitric oxide synthase proteinC-terminal PDZ domain ligand of neuronal nitric oxide synthase (CAPON)C-terminal PDZ ligand of neuronal nitric oxide synthase proteinligand of neuronal nitric oxide synthase with carhistone-lysine N-methyltransferase ASH1LASH1-like proteinabsent small and homeotic disks protein 1 homologash1 (absent, small, or homeotic)-likelysine N-methyltransferase 2Hprobable histone-lysine N-methyltransferase ASH1L
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000361897, ENST00000530878, 
ENST00000454693, ENST00000493151, 
Fusion gene scores* DoF score15 X 9 X 8=108017 X 13 X 7=1547
# samples 1818
** MAII scorelog2(18/1080*10)=-2.58496250072116
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(18/1547*10)=-3.10340438511936
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: NOS1AP [Title/Abstract] AND ASH1L [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointNOS1AP(162257226)-ASH1L(155452240), # samples:1
Anticipated loss of major functional domain due to fusion event.NOS1AP-ASH1L seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
NOS1AP-ASH1L seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
NOS1AP-ASH1L seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
NOS1AP-ASH1L seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneNOS1AP

GO:0098974

postsynaptic actin cytoskeleton organization

26869880

TgeneASH1L

GO:0097676

histone H3-K36 dimethylation

26002201


check buttonFusion gene breakpoints across NOS1AP (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across ASH1L (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUADTCGA-L9-A444-01ANOS1APchr1

162257226

+ASH1Lchr1

155452240

-


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Fusion Gene ORF analysis for NOS1AP-ASH1L

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000361897ENST00000548830NOS1APchr1

162257226

+ASH1Lchr1

155452240

-
5CDS-3UTRENST00000530878ENST00000548830NOS1APchr1

162257226

+ASH1Lchr1

155452240

-
In-frameENST00000361897ENST00000368346NOS1APchr1

162257226

+ASH1Lchr1

155452240

-
In-frameENST00000361897ENST00000392403NOS1APchr1

162257226

+ASH1Lchr1

155452240

-
In-frameENST00000530878ENST00000368346NOS1APchr1

162257226

+ASH1Lchr1

155452240

-
In-frameENST00000530878ENST00000392403NOS1APchr1

162257226

+ASH1Lchr1

155452240

-
intron-3CDSENST00000454693ENST00000368346NOS1APchr1

162257226

+ASH1Lchr1

155452240

-
intron-3CDSENST00000454693ENST00000392403NOS1APchr1

162257226

+ASH1Lchr1

155452240

-
intron-3CDSENST00000493151ENST00000368346NOS1APchr1

162257226

+ASH1Lchr1

155452240

-
intron-3CDSENST00000493151ENST00000392403NOS1APchr1

162257226

+ASH1Lchr1

155452240

-
intron-3UTRENST00000454693ENST00000548830NOS1APchr1

162257226

+ASH1Lchr1

155452240

-
intron-3UTRENST00000493151ENST00000548830NOS1APchr1

162257226

+ASH1Lchr1

155452240

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000530878NOS1APchr1162257226+ENST00000368346ASH1Lchr1155452240-1155667422191632980
ENST00000530878NOS1APchr1162257226+ENST00000392403ASH1Lchr1155452240-1075467422191482975
ENST00000361897NOS1APchr1162257226+ENST00000368346ASH1Lchr1155452240-1155467221991612980
ENST00000361897NOS1APchr1162257226+ENST00000392403ASH1Lchr1155452240-1075267221991462975

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000530878ENST00000368346NOS1APchr1162257226+ASH1Lchr1155452240-0.0002465750.9997534
ENST00000530878ENST00000392403NOS1APchr1162257226+ASH1Lchr1155452240-0.0002396580.9997603
ENST00000361897ENST00000368346NOS1APchr1162257226+ASH1Lchr1155452240-0.000246010.999754
ENST00000361897ENST00000392403NOS1APchr1162257226+ASH1Lchr1155452240-0.0002392590.9997607

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Fusion Genomic Features for NOS1AP-ASH1L


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

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Fusion Protein Features for NOS1AP-ASH1L


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr1:162257226/chr1:155452240)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneASH1Lchr1:162257226chr1:155452240ENST000003683461281380_14241402970.0Compositional biasNote=Pro-rich
TgeneASH1Lchr1:162257226chr1:155452240ENST000003683461281580_17911402970.0Compositional biasNote=Ser-rich
TgeneASH1Lchr1:162257226chr1:155452240ENST000003924031281380_14241402965.0Compositional biasNote=Pro-rich
TgeneASH1Lchr1:162257226chr1:155452240ENST000003924031281580_17911402965.0Compositional biasNote=Ser-rich
TgeneASH1Lchr1:162257226chr1:155452240ENST000003683461281347_13591402970.0DNA bindingNote=A.T hook 2
TgeneASH1Lchr1:162257226chr1:155452240ENST000003683461281847_18591402970.0DNA bindingNote=A.T hook 3
TgeneASH1Lchr1:162257226chr1:155452240ENST00000368346128887_8991402970.0DNA bindingNote=A.T hook 1
TgeneASH1Lchr1:162257226chr1:155452240ENST000003924031281347_13591402965.0DNA bindingNote=A.T hook 2
TgeneASH1Lchr1:162257226chr1:155452240ENST000003924031281847_18591402965.0DNA bindingNote=A.T hook 3
TgeneASH1Lchr1:162257226chr1:155452240ENST00000392403128887_8991402965.0DNA bindingNote=A.T hook 1
TgeneASH1Lchr1:162257226chr1:155452240ENST000003683461282091_21421402970.0DomainAWS
TgeneASH1Lchr1:162257226chr1:155452240ENST000003683461282145_22611402970.0DomainSET
TgeneASH1Lchr1:162257226chr1:155452240ENST000003683461282269_22851402970.0DomainPost-SET
TgeneASH1Lchr1:162257226chr1:155452240ENST000003683461282463_25331402970.0DomainBromo
TgeneASH1Lchr1:162257226chr1:155452240ENST000003683461282661_27981402970.0DomainBAH
TgeneASH1Lchr1:162257226chr1:155452240ENST000003924031282091_21421402965.0DomainAWS
TgeneASH1Lchr1:162257226chr1:155452240ENST000003924031282145_22611402965.0DomainSET
TgeneASH1Lchr1:162257226chr1:155452240ENST000003924031282269_22851402965.0DomainPost-SET
TgeneASH1Lchr1:162257226chr1:155452240ENST000003924031282463_25331402965.0DomainBromo
TgeneASH1Lchr1:162257226chr1:155452240ENST000003924031282661_27981402965.0DomainBAH
TgeneASH1Lchr1:162257226chr1:155452240ENST000003683461282069_22881402970.0RegionNote=Catalytic domain
TgeneASH1Lchr1:162257226chr1:155452240ENST000003924031282069_22881402965.0RegionNote=Catalytic domain
TgeneASH1Lchr1:162257226chr1:155452240ENST000003683461282585_26311402970.0Zinc fingerNote=PHD-type
TgeneASH1Lchr1:162257226chr1:155452240ENST000003924031282585_26311402965.0Zinc fingerNote=PHD-type

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneNOS1APchr1:162257226chr1:155452240ENST00000361897+310322_36390507.0Coiled coilOntology_term=ECO:0000255
HgeneNOS1APchr1:162257226chr1:155452240ENST00000493151+12322_3630212.0Coiled coilOntology_term=ECO:0000255
HgeneNOS1APchr1:162257226chr1:155452240ENST00000530878+310322_36390502.0Coiled coilOntology_term=ECO:0000255
HgeneNOS1APchr1:162257226chr1:155452240ENST00000361897+310301_30890507.0Compositional biasNote=Poly-Gln
HgeneNOS1APchr1:162257226chr1:155452240ENST00000493151+12301_3080212.0Compositional biasNote=Poly-Gln
HgeneNOS1APchr1:162257226chr1:155452240ENST00000530878+310301_30890502.0Compositional biasNote=Poly-Gln
HgeneNOS1APchr1:162257226chr1:155452240ENST00000361897+31026_19690507.0DomainPID
HgeneNOS1APchr1:162257226chr1:155452240ENST00000493151+1226_1960212.0DomainPID
HgeneNOS1APchr1:162257226chr1:155452240ENST00000530878+31026_19690502.0DomainPID
HgeneNOS1APchr1:162257226chr1:155452240ENST00000361897+310504_50690507.0MotifPDZ-binding
HgeneNOS1APchr1:162257226chr1:155452240ENST00000493151+12504_5060212.0MotifPDZ-binding
HgeneNOS1APchr1:162257226chr1:155452240ENST00000530878+310504_50690502.0MotifPDZ-binding


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Fusion Gene Sequence for NOS1AP-ASH1L


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>59665_59665_1_NOS1AP-ASH1L_NOS1AP_chr1_162257226_ENST00000361897_ASH1L_chr1_155452240_ENST00000368346_length(transcript)=11554nt_BP=672nt
CGTCGCCTTTTCTTCTTCGTCCCGGGCGGTGCGTTCCACTGCTCTGGGGCCGGCGCCGCGCCCAGTCCCGCTTCGGGCCGCAAGCCCCAC
CGCTCCCCTCCCCGGGCAGGGGCGCCGCGCAGCCCGCTCCCGCCGCCACCTCCTCCCCTGCCGCCCTCCTAGCCGGCAGGAATTGCGCGA
CCACAGCGCCGCTCGCGTCGCCCGCATCAGCTCAGCCCGCTGCCGCTCGGCCCTCGGCACCGCTCCGGGTCCGGCCGCCGCGCGGCCAGG
GCTCCCCCTGCCCAGCGCTCCCAGGCCCCGCCACGCGTCGCCGCGCCCAGCTCCAGTCTCCCCTCCCCGGGGTCTCGCCAGCCCCTTCCT
GCAGCCGCCGCCTCCGAAGGAGCGGGTCCGCCGCGGGTAACCATGCCTAGCAAAACCAAGTACAACCTTGTGGACGATGGGCACGACCTG
CGGATCCCCTTGCACAACGAGGACGCCTTCCAGCACGGCATCTGCTTTGAGGCCAAGTACGTAGGAAGCCTGGACGTGCCAAGGCCCAAC
AGCAGGGTGGAGATCGTGGCTGCCATGCGCCGGATACGGTATGAGTTTAAAGCCAAGAACATCAAGAAGAAGAAAGTGAGCATTATGGTT
TCAGTGGATGGAGTGAAAGTGATTCTGAAGAAGAAGAAAAAGGACCCTTCAAAGTTGTACAAGAAAGCAGATGATGTTGCAGCCATTGAA
TGCCAGTCTGAAGAAGTCATCCGTCTTCATTCACAGGGAGAAAACAATCCTTTGTCTAAGAAGCTGTCTCCAGTACACTCAGAAATGGCA
GATTATATTAATGCAACGCCATCTACTCTTCTTGGTAGCCGGGATCCTGATTTAAAGGACAGAGCATTACTTAATGGAGGAACTAGTGTA
ACAGAAAAGTTGGCACAGCTGATTGCTACCTGTCCTCCTTCCAAGTCTTCCAAGACAAAACCGAAGAAGTTAGGAACTGGCACTACAGCA
GGATTGGTTAGCAAGGATTTGATCAGGAAAGCAGGTGTTGGCTCTGTAGCTGGAATAATACATAAGGACTTAATAAAAAAGCCAACCATC
AGCACAGCAGTTGGATTGGTAACTAAAGATCCTGGGAAAAAGCCAGTGTTTAATGCAGCAGTAGGATTGGTCAATAAGGACTCTGTGAAA
AAACTGGGAACTGGCACTACAGCGGTATTCATTAATAAAAACTTAGGCAAAAAGCCAGGAACTATCACTACAGTAGGACTGCTAAGCAAA
GATTCAGGAAAGAAGCTAGGAATTGGTATTGTTCCAGGTTTAGTGCATAAAGAGTCTGGCAAGAAGTTAGGACTTGGCACTGTGGTTGGA
CTGGTTAATAAAGATTTGGGAAAGAAATTGGGTTCTACTGTTGGCCTAGTGGCCAAGGACTGTGCAAAGAAGATTGTAGCAAGTTCAGCA
ATGGGATTGGTTAATAAGGACATTGGAAAGAAACTAATGAGTTGTCCTTTGGCAGGTCTGATCAGTAAAGATGCCATAAACCTTAAAGCC
GAAGCACTGCTCCCCACTCAGGAACCGCTTAAGGCTTCTTGTAGTACAAACATCAATAATCAGGAAAGTCAGGAACTTTCTGAATCCCTG
AAAGATAGTGCCACCAGCAAAACTTTTGAAAAGAATGTTGTACGGCAGAATAAAGAAAGCATATTGGAAAAGTTCTCAGTACGAAAAGAA
ATCATTAATTTGGAGAAAGAAATGTTTAATGAAGGAACATGCATTCAGCAAGACAGTTTCTCATCCAGTGAAAAGGGATCTTATGAAACC
TCAAAGCATGAAAAGCAGCCTCCTGTATATTGCACTTCTCCGGACTTTAAAATGGGAGGTGCTTCTGATGTATCTACCGCTAAATCCCCA
TTCAGTGCAGTAGGAGAAAGCAATCTCCCTTCCCCATCACCTACTGTATCTGTTAATCCTTTAACCAGAAGTCCCCCTGAAACTTCTTCA
CAGTTGGCTCCTAATCCATTACTTTTAAGTTCTACTACAGAACTAATCGAAGAAATTTCTGAATCTGTTGGAAAGAACCAGTTTACTTCT
GAAAGTACCCACTTGAACGTTGGTCATAGGTCAGTTGGTCATAGTATAAGTATTGAATGTAAAGGGATTGATAAAGAGGTAAATGATTCA
AAAACTACCCATATAGATATTCCAAGAATAAGCTCTTCCCTTGGAAAAAAGCCAAGTTTGACTTCTGAATCCAGCATTCATACTATTACT
CCTTCAGTTGTTAACTTCACTAGTTTATTTAGTAATAAGCCTTTTTTAAAACTGGGTGCAGTATCTGCATCAGACAAACACTGCCAAGTT
GCTGAAAGCCTAAGTACTAGTTTGCAGTCCAAACCATTAAAAAAAAGAAAAGGAAGAAAACCTCGGTGGACTAAAGTGGTGGCAAGAAGC
ACATGCCGGTCTCCAAAAGGGCTAGAATTAGAAAGATCAGAGCTTTTTAAAAACGTTTCATGTAGCTCACTATCAAATAGTAATTCTGAG
CCAGCCAAGTTTATGAAAAACATTGGACCCCCTTCATTTGTAGATCATGACTTCCTTAAACGCCGATTGCCAAAGTTGAGCAAATCCACA
GCTCCATCTCTTGCTCTCTTAGCTGATAGTGAAAAACCATCTCATAAGTCTTTTGCTACTCACAAACTATCCTCCAGTATGTGTGTCTCT
AGTGACCTTTTGTCTGATATTTATAAGCCCAAAAGAGGAAGGCCTAAATCTAAGGAGATGCCTCAACTGGAAGGGCCACCTAAAAGGACT
TTAAAAATCCCTGCTTCTAAAGTGTTTTCTTTACAGTCTAAGGAAGAACAAGAACCCCCAATTTTACAGCCAGAAATTGAAATCCCTTCC
TTCAAACAAGGTCTGTCTGTGTCTCCTTTTCCAAAAAAGAGAGGCAGGCCTAAGAGGCAAATGAGGTCACCAGTCAAGATGAAGCCACCT
GTACTGTCAGTGGCTCCATTTGTTGCCACTGAAAGTCCAAGCAAGCTAGAATCTGAAAGTGACAACCATAGAAGTAGCAGTGATTTCTTT
GAGAGCGAGGATCAACTTCAGGATCCAGATGACCTAGATGACAGTCATAGGCCAAGTGTCTGTAGTATGAGTGACCTTGAGATGGAACCA
GATAAAAAAATTACCAAGAGAAACAATGGACAATTAATGAAAACAATTATCCGCAAAATAAATAAAATGAAGACTTTAAAGAGAAAGAAA
CTGTTGAATCAGATTCTTTCAAGTTCTGTAGAATCAAGTAATAAAGGGAAAGTGCAATCCAAACTCCATAATACGGTATCAAGTCTTGCT
GCCACATTTGGCTCTAAATTGGGCCAACAGATAAATGTCAGCAAGAAAGGAACCATTTATATAGGAAAGAGAAGAGGTCGCAAACCAAAA
ACTGTCTTAAATGGTATTCTTTCTGGTAGTCCTACTAGCCTTGCTGTTCTTGAGCAAACAGCTCAACAGGCAGCTGGGTCAGCATTAGGA
CAGATTCTTCCCCCATTACTGCCTTCATCTGCTAGTAGTTCTGAGATTCTTCCATCACCTATTTGCTCTCAGTCTTCTGGGACTAGTGGA
GGTCAGAGCCCTGTAAGTAGTGATGCAGGTTTTGTTGAACCCAGTTCAGTGCCATATTTGCATTTACACTCCAGACAGGGCAGTATGATT
CAGACTCTTGCAATGAAGAAGGCCTCAAAGGGGAGGAGGCGGTTATCTCCTCCTACTTTGTTGCCAAATTCTCCTTCGCACTTGAGTGAA
CTCACATCTCTAAAAGAAGCTACTCCTTCCCCAATCAGTGAGTCTCATAGTGATGAGACCATTCCCAGTGATAGTGGAATTGGAACAGAT
AATAACAGCACATCAGACAGGGCAGAGAAATTTTGTGGGCAAAAAAAGAGGAGGCATTCTTTTGAGCATGTTTCTCTGATTCCCCCTGAA
ACCTCTACAGTGCTAAGCAGTCTTAAAGAAAAACATAAACACAAATGTAAGCGCAGGAATCATGATTACCTCAGCTATGACAAGATGAAA
AGGCAGAAACGAAAACGGAAAAAGAAATATCCCCAGCTTCGAAATAGACAGGATCCAGACTTTATTGCAGAGCTGGAGGAACTAATAAGT
CGCCTAAGTGAAATTCGGATCACTCATCGAAGTCATCATTTTATCCCCCGAGATCTTCTGCCAACTATCTTTCGAATCAACTTTAATAGT
TTCTATACACATCCTTCTTTCCCCTTAGACCCTTTGCACTACATTCGAAAACCTGACTTAAAAAAGAAAAGAGGGAGACCCCCTAAGATG
AGGGAGGCAATGGCTGAAATGCCTTTTATGCACAGCCTTAGTTTTCCTCTTTCTAGTACTGGATTCTATCCATCTTATGGTATGCCTTAC
TCTCCTTCACCCCTTACAGCTGCTCCCATAGGATTAGGTTACTATGGAAGGTATCCTCCCACTCTTTATCCACCTCCTCCATCTCCTTCT
TTCACCACGCCACTTCCACCTCCTTCCTATATGCATGCTGGTCATTTACTTCTCAATCCTGCCAAATACCATAAGAAAAAGCATAAGCTA
CTTCGACAGGAGGCCTTTCTTACAACCAGCAGGACTCCCCTCCTTTCCATGAGTACCTACCCCAGTGTTCCTCCTGAGATGGCCTATGGT
TGGATGGTTGAGCACAAACACAGGCACCGTCACAAACACAGAGAACACCGTTCTTCTGAACAACCCCAGGTTTCTATGGACACTGGCTCT
TCCCGATCTGTCCTGGAATCTTTGAAGCGCTATAGATTTGGAAAGGATGCTGTTGGAGAGCGATATAAGCATAAGGAAAAGCACCGTTGT
CACATGTCCTGCCCTCATCTCTCTCCTTCAAAAAGCTTAATAAACAGAGAGGAACAGTGGGTCCACCGAGAGCCTTCAGAATCTAGTCCA
TTGGCCTTGGGATTGCAGACACCTTTACAGATTGACTGTTCAGAAAGTTCTCCAAGCTTATCCCTTGGAGGATTCACTCCCAACTCTGAG
CCAGCCAGCAGTGATGAACATACAAACCTTTTCACAAGTGCAATAGGCAGCTGCAGAGTTTCAAACCCTAACTCCAGTGGCCGGAAGAAA
TTAACTGACAGCCCTGGACTCTTTTCTGCACAGGACACTTCACTAAATCGGCTTCACAGAAAGGAGTCACTGCCTTCTAACGAAAGGGCA
GTACAGACTTTGGCAGGCTCCCAGCCAACCTCTGATAAACCCTCCCAGCGGCCATCAGAGAGCACAAATTGTAGCCCTACCCGGAAAAGG
TCTTCATCTGAGAGTACTTCTTCAACAGTAAACGGAGTTCCCTCTCGAAGTCCAAGATTAGTTGCTTCTGGGGATGACTCTGTGGATAGT
CTGCTGCAGCGGATGGTACAAAATGAGGACCAAGAGCCCATGGAGAAAAGTATTGATGCTGTGATTGCAACTGCCTCTGCACCACCTTCT
TCCAGTCCAGGCCGTAGCCACAGCAAGGACCGAACCCTGGGAAAACCAGACAGCCTTTTAGTGCCTGCAGTCACAAGTGACTCTTGCAAT
AATAGCATCTCACTCCTATCTGAAAAGTTGACAAGCAGCTGTTCCCCCCATCATATCAAGAGAAGTGTAGTGGAAGCTATGCAACGCCAA
GCTCGGAAAATGTGCAATTACGACAAAATCTTGGCCACAAAGAAAAACCTAGACCATGTCAATAAAATCTTAAAAGCCAAAAAACTTCAA
AGGCAGGCCAGGACAGGGAATAACTTTGTGAAACGTAGGCCAGGTCGACCTCGGAAATGTCCCCTTCAGGCTGTCGTATCAATGCAAGCA
TTCCAGGCTGCTCAGTTTGTCAACCCAGAATTGAACAGAGACGAGGAAGGAGCAGCACTGCACCTCAGTCCTGACACAGTTACAGATGTA
ATTGAGGCTGTTGTTCAGAGTGTAAATCTGAACCCAGAACATAAAAAGGGGTTGAAGAGAAAAGGTTGGCTATTGGAAGAACAGACCAGA
AAAAAGCAGAAGCCATTACCAGAGGAAGAAGAGCAAGAGAATAATAAAAGCTTTAATGAAGCACCAGTTGAGATTCCCAGTCCTTCTGAA
ACCCCAGCTAAACCTTCTGAACCTGAAAGTACCTTGCAGCCTGTGCTTTCTCTCATCCCAAGGGAAAAGAAGCCCCCACGTCCCCCAAAG
AAGAAGTATCAGAAAGCAGGGCTGTATTCTGACGTTTACAAAACTACAGACCCAAAGAGTCGATTGATCCAATTAAAGAAAGAGAAGCTG
GAGTATACTCCAGGAGAGCATGAATATGGATTATTTCCAGCGCCCATTCATGTTGTGTTTTTTGTTTCAGGAAAGTATCTAAGACAAAAG
AGAATTGACTTCCAGCTTCCTTATGATATCCTTTGGCAGTGGAAACACAATCAGCTATACAAAAAGCCAGATGTCCCACTATATAAGAAA
ATTCGTTCAAATGTCTACGTTGATGTCAAACCCCTTTCTGGTTACGAAGCTACCACCTGTAACTGTAAGAAGCCAGATGATGACACCAGG
AAGGGCTGTGTTGATGACTGCCTCAATAGAATGATCTTTGCTGAGTGTTCCCCCAACACTTGCCCATGTGGCGAGCAATGCTGTAACCAG
AGGATACAGAGGCATGAATGGGTGCAATGTCTAGAACGATTTCGAGCTGAGGAAAAAGGTTGGGGAATCAGAACCAAAGAGCCCCTAAAA
GCTGGGCAGTTCATCATTGAATACCTAGGGGAGGTCGTCAGTGAACAGGAGTTCAGGAACAGGATGATTGAGCAGTATCATAATCACAGT
GACCACTACTGCCTGAACCTGGATAGTGGGATGGTGATTGACAGTTACCGCATGGGAAATGAGGCCCGATTCATCAACCATAGCTGTGAC
CCAAATTGTGAAATGCAGAAATGGTCTGTTAATGGAGTATACCGGATTGGACTCTATGCTCTTAAAGACATGCCAGCTGGGACTGAACTC
ACTTATGATTATAACTTTCATTCCTTCAATGTGGAAAAACAGCAACTTTGTAAGTGTGGCTTTGAGAAATGTCGAGGAATCATCGGAGGC
AAGAGTCAGCGTGTGAATGGACTCACCAGCAGCAAAAACAGCCAGCCCATGGCCACACACAAAAAATCTGGACGGTCAAAAGAGAAGAGA
AAGTCTAAGCACAAGCTGAAGAAAAGGAGAGGCCATCTCTCTGAGGAACCCAGTGAAAATATCAACACCCCAACTAGATTGACCCCCCAA
TTACAGATGAAGCCAATGTCCAATCGTGAAAGGAACTTTGTGTTAAAGCATCATGTATTCTTGGTCCGAAACTGGGAGAAGATTCGTCAA
AAACAGGAGGAAGTAAAGCACACCAGTGATAATATTCACTCAGCATCATTATATACCCGTTGGAATGGGATCTGCCGAGATGATGGGAAT
ATCAAGTCTGATGTCTTCATGACCCAGTTCTCTGCCCTGCAGACAGCTCGATCTGTTCGAACAAGACGGTTGGCAGCTGCAGAGGAAAAT
ATTGAAGTGGCTCGGGCAGCCCGCCTAGCCCAGATCTTCAAAGAAATTTGTGATGGTATCATCTCTTATAAAGATTCTTCCCGGCAAGCA
CTGGCAGCTCCACTTTTGAACCTTCCCCCAAAGAAAAAGAATGCTGATTATTATGAGAAGATCTCTGATCCCCTAGATCTTATCACCATA
GAGAAGCAGATCCTCACTGGTTACTATAAGACAGTGGAAGCTTTTGATGCTGACATGCTCAAAGTCTTTCGGAATGCTGAGAAGTACTAT
GGGCGTAAATCCCCAGTTGGGAGAGATGTTTGTCGTCTACGAAAGGCCTATTACAATGCCCGGCATGAGGCATCAGCCCAGATTGATGAG
ATTGTGGGAGAGACAGCAAGTGAGGCAGACAGCAGTGAGACCTCAGTCTCTGAAAAGGAGAATGGGCATGAGAAGGACGACGATGTTATT
CGCTGTATCTGTGGCCTCTACAAGGATGAAGGTCTCATGATCCAGTGTGACAAGTGCATGGTATGGCAGCACTGTGATTGTATGGGAGTG
AACTCAGATGTGGAGCACTACCTTTGTGAGCAGTGTGACCCAAGGCCTGTGGACAGGGAGGTTCCCATGATCCCTCGGCCCCACTATGCC
CAACCTGGCTGTGTCTACTTCATCTGTTTGCTCCGAGATGACTTGCTGCTTCGTCAGGGTGACTGTGTGTATCTGATGAGGGATAGTCGG
CGCACCCCTGATGGCCACCCGGTCCGTCAGTCCTATCGACTGTTATCTCACATTAACCGAGATAAACTTGACATCTTTCGCATTGAGAAG
CTTTGGAAGAATGAAAAAGAGGAACGGTTTGCCTTTGGTCACCATTATTTCCGTCCCCACGAAACACACCACTCTCCATCCCGTCGGTTC
TATCATAATGAACTATTTCGGGTGCCACTCTATGAGATCATTCCCTTGGAGGCTGTAGTGGGGACCTGCTGTGTGTTGGACCTTTATACG
TATTGTAAAGGGAGACCCAAAGGAGTAAAGGAGCAAGATGTGTACATCTGTGATTATCGGCTTGACAAGTCAGCACACCTGTTTTACAAG
ATCCACCGGAACCGCTATCCTGTCTGCACCAAACCCTATGCTTTTGATCACTTCCCCAAGAAGCTCACTCCCAAAAAAGATTTCTCGCCT
CATTACGTCCCAGACAACTACAAGAGGAATGGAGGACGATCATCCTGGAAGTCTGAGCGCTCAAAGCCACCCCTAAAAGACTTGGGCCAG
GAGGATGATGCTCTACCCTTGATTGAAGAGGTTCTAGCCAGTCAAGAGCAAGCAGCCAATGAGATACCCAGCCTGGAGGAGCCAGAACGG
GAAGGGGCCACTGCTAACGTCAGTGAGGGTGAAAAAAAAACAGAGGAAAGTAGTCAAGAACCCCAGTCAACCTGTACCCCTGAGGAACGA
CGGCATAACCAACGGGAACGACTCAACCAGATCTTGCTCAATCTCCTTGAAAAAATCCCTGGAAAAAATGCCATTGATGTGACCTACTTG
CTGGAGGAAGGATCAGGCAGGAAACTGCGAAGGCGTACTTTGTTTATCCCAGAAAACAGCTTTCGAAAGTGACCCTCAAAGAATGAGAAC
CTCAAGCATCTGGGATCCAGTGGAGCTAATCAGTCCTGCCTCCTGCTCTCTGGGTATAGACAGGGGTGGGAAGGGTCCATCTGGGCAAGG
GGAATGGGGCCATGTTGTTGACATTAGGTACTTAATAAGCCTTGGAGCTAGTGGAGAGGGAGAGGAAAGGGTTCTGTCCAAGACAGTTCA
GGTTAATTAATTTTCTTCTCCATTGCTTCACCTTAAGGGTTAATAATGTAGAGAGGAGGGAGGACCACATTGATGACCAGAACCTACTGG
TACTTTATAGCATTTGCCCCACCCCACAGCTTAGGTTTTTCTGTCATCCTCAGATCCCACAGGCATTGCGAAGAAGCTGCTTCCTATACC
CAGGTATAACTCAAAATCCAAAGGGATAGGGCCAGGATCCCTATTCCTACCCCATCTATTCTCTGTTGGCTCCAAGAGCTACCCCAGAGA
CCTTAAACAGAAACAGTAGCTGAGGCTTCTTCCTAGATACCTGACTAGGGAAGTTTGTCTCTCCTTTCTTGCCCAACCAGGTCAAAGTAA
AATGTGAGTTGACAGCTCAAAGCACTTGTAACTGCTGCCCCCTCCCTACCTCTACTCCCCAAAATGGAATCATGGGATAGGGAAGGCCCC
CATGGGGTCAGAAGGGCACGGTAGTTCTTGCAATTATTTTTGTTTTACCCTTCATAACCTGTCAAACATATTTTTTTCTAATGAGAAAGC
CAGGCCCCCGCCAGCACACATGCTGTTTTTAATGCGCTGTAGTTCTTGTGTGTCTGCTGTGCTGTGCAAATGGAGATTCAGTTCAAAATA
AAATCATTTAAAAACCTACATAAAAAGAACTCTAAACCCACCCCTGCAACAAAAGTCACTACATAAACTGTTCAGCAGTATTCACCTATC
AGAGTATTTGTTGTGAGTATAGATTATCAATTGAAAACACTACTCTTGTTTTCTTAATTGTACAGTTTTCAATGTCCCTTTCTTAAAGAG
ACAGTATATTTCTCTTCACCCCTAGCCCATCTTCCCTCACCCTCCTGAATGACATCAGGAGGTATATCCAGGGTGTCTCCTTCCTTCCTA
CTCTCTTGACCAGAAGTTAACAGACTATACTGTCTCTTTAAAAATAAAATTTAAAAAGCTTTGTTGTCTTTTCAGACATACATATGCATA
TATGTTTTAGATGTTCTTATAAGAGAAAAGATGGTTTTTAAATGTGCCAAGTTGTGTGTGTGTGTGTATATATATGTGTGTATGTGTGTG
TATATATATATGTGTGTGTGTATATATATACACACACACACACACACCTGCTGTGTGATTGGTAAGCAATACAATAGTAAACATGTCCCC
ATTACTTTTTTCTAATATTGGACCAATGCTGTCCTAATTGTACATTTCCCCTTATGGTGACGATGCTCTGACTCGTTTAGGTAGACACAT
TGACCACCTTCCATTCCATTAAATATTTTTTCCTTTTTCCCCTTTCTGTGTCATTCTTGAGGAAAAAACAAAAGAGAGAGGGGATGCCAA
TGATCCCCTTGAGCAGAGAAAAAGCAAAATAAATATTTTATTAAAGAAAAAAGAGAATTAAGAAAATAGTTTGGAGTATTTTCTTACTGT
AGAGAAGCACTGTACATTACTAAGAGACCTGGGTATAAGATACTCACATGTGGAGCTGGAAAAATCGCATGTCCAAGCCCGTTTGAGTGG
TTTCTTTTGTTTTTCATTGCAGGGAGTGGGTGGGAGGGAGGTGGGACTAGGGGCACTTTGGGGGTCTCCTTTTAGTCAAAAGCGAGAAAA
TGACAAGAAAGAGATTAAAATTCAATGTTTCCTTTATAGTGTTAAACACTAAAATTTTAAAAAAGATGAAAAAGAAAAAAAAACTTTGTA
AAATGCGAGAACAGAAGCAAAAGACACTACGCTCTGTCATTTTATCTTTCTTTTGTTGAAAGACTAAAAAAAAACTGAAATGTTTTTTAG
ACAATCAAATGTTAGGTAAGTGCAAAAACTTGTTTTTTCTTACTGGTGTAGAAATTAATGCCTTTTTTTATTTTTCAGTTATTTTATAAT
AACGAAATAAAAAGAACCCCCCAGCTGCCAGGCGGGTTTTGGTGTTTGAAATGCGGGGCAAAGCACTACATCACTGCAAATAGATACAGA
GTTAGTCTGCATGTCTGTAGGCTGTGTGATTGCGGAAAATATAAATGCTGCTAATATATTTCCTTTTTACAAAAGCATATCTAAATAGAT
GATTGTTTTGATGTTAATCTTTGTAAATTATGTATTACCAATTTTAACATTGGATGTAATTGCATACAAAGCTTGCATCTCAATCCTTGA

>59665_59665_1_NOS1AP-ASH1L_NOS1AP_chr1_162257226_ENST00000361897_ASH1L_chr1_155452240_ENST00000368346_length(amino acids)=2980AA_BP=151
MPLGPRHRSGSGRRAARAPPAQRSQAPPRVAAPSSSLPSPGSRQPLPAAAASEGAGPPRVTMPSKTKYNLVDDGHDLRIPLHNEDAFQHG
ICFEAKYVGSLDVPRPNSRVEIVAAMRRIRYEFKAKNIKKKKVSIMVSVDGVKVILKKKKKDPSKLYKKADDVAAIECQSEEVIRLHSQG
ENNPLSKKLSPVHSEMADYINATPSTLLGSRDPDLKDRALLNGGTSVTEKLAQLIATCPPSKSSKTKPKKLGTGTTAGLVSKDLIRKAGV
GSVAGIIHKDLIKKPTISTAVGLVTKDPGKKPVFNAAVGLVNKDSVKKLGTGTTAVFINKNLGKKPGTITTVGLLSKDSGKKLGIGIVPG
LVHKESGKKLGLGTVVGLVNKDLGKKLGSTVGLVAKDCAKKIVASSAMGLVNKDIGKKLMSCPLAGLISKDAINLKAEALLPTQEPLKAS
CSTNINNQESQELSESLKDSATSKTFEKNVVRQNKESILEKFSVRKEIINLEKEMFNEGTCIQQDSFSSSEKGSYETSKHEKQPPVYCTS
PDFKMGGASDVSTAKSPFSAVGESNLPSPSPTVSVNPLTRSPPETSSQLAPNPLLLSSTTELIEEISESVGKNQFTSESTHLNVGHRSVG
HSISIECKGIDKEVNDSKTTHIDIPRISSSLGKKPSLTSESSIHTITPSVVNFTSLFSNKPFLKLGAVSASDKHCQVAESLSTSLQSKPL
KKRKGRKPRWTKVVARSTCRSPKGLELERSELFKNVSCSSLSNSNSEPAKFMKNIGPPSFVDHDFLKRRLPKLSKSTAPSLALLADSEKP
SHKSFATHKLSSSMCVSSDLLSDIYKPKRGRPKSKEMPQLEGPPKRTLKIPASKVFSLQSKEEQEPPILQPEIEIPSFKQGLSVSPFPKK
RGRPKRQMRSPVKMKPPVLSVAPFVATESPSKLESESDNHRSSSDFFESEDQLQDPDDLDDSHRPSVCSMSDLEMEPDKKITKRNNGQLM
KTIIRKINKMKTLKRKKLLNQILSSSVESSNKGKVQSKLHNTVSSLAATFGSKLGQQINVSKKGTIYIGKRRGRKPKTVLNGILSGSPTS
LAVLEQTAQQAAGSALGQILPPLLPSSASSSEILPSPICSQSSGTSGGQSPVSSDAGFVEPSSVPYLHLHSRQGSMIQTLAMKKASKGRR
RLSPPTLLPNSPSHLSELTSLKEATPSPISESHSDETIPSDSGIGTDNNSTSDRAEKFCGQKKRRHSFEHVSLIPPETSTVLSSLKEKHK
HKCKRRNHDYLSYDKMKRQKRKRKKKYPQLRNRQDPDFIAELEELISRLSEIRITHRSHHFIPRDLLPTIFRINFNSFYTHPSFPLDPLH
YIRKPDLKKKRGRPPKMREAMAEMPFMHSLSFPLSSTGFYPSYGMPYSPSPLTAAPIGLGYYGRYPPTLYPPPPSPSFTTPLPPPSYMHA
GHLLLNPAKYHKKKHKLLRQEAFLTTSRTPLLSMSTYPSVPPEMAYGWMVEHKHRHRHKHREHRSSEQPQVSMDTGSSRSVLESLKRYRF
GKDAVGERYKHKEKHRCHMSCPHLSPSKSLINREEQWVHREPSESSPLALGLQTPLQIDCSESSPSLSLGGFTPNSEPASSDEHTNLFTS
AIGSCRVSNPNSSGRKKLTDSPGLFSAQDTSLNRLHRKESLPSNERAVQTLAGSQPTSDKPSQRPSESTNCSPTRKRSSSESTSSTVNGV
PSRSPRLVASGDDSVDSLLQRMVQNEDQEPMEKSIDAVIATASAPPSSSPGRSHSKDRTLGKPDSLLVPAVTSDSCNNSISLLSEKLTSS
CSPHHIKRSVVEAMQRQARKMCNYDKILATKKNLDHVNKILKAKKLQRQARTGNNFVKRRPGRPRKCPLQAVVSMQAFQAAQFVNPELNR
DEEGAALHLSPDTVTDVIEAVVQSVNLNPEHKKGLKRKGWLLEEQTRKKQKPLPEEEEQENNKSFNEAPVEIPSPSETPAKPSEPESTLQ
PVLSLIPREKKPPRPPKKKYQKAGLYSDVYKTTDPKSRLIQLKKEKLEYTPGEHEYGLFPAPIHVVFFVSGKYLRQKRIDFQLPYDILWQ
WKHNQLYKKPDVPLYKKIRSNVYVDVKPLSGYEATTCNCKKPDDDTRKGCVDDCLNRMIFAECSPNTCPCGEQCCNQRIQRHEWVQCLER
FRAEEKGWGIRTKEPLKAGQFIIEYLGEVVSEQEFRNRMIEQYHNHSDHYCLNLDSGMVIDSYRMGNEARFINHSCDPNCEMQKWSVNGV
YRIGLYALKDMPAGTELTYDYNFHSFNVEKQQLCKCGFEKCRGIIGGKSQRVNGLTSSKNSQPMATHKKSGRSKEKRKSKHKLKKRRGHL
SEEPSENINTPTRLTPQLQMKPMSNRERNFVLKHHVFLVRNWEKIRQKQEEVKHTSDNIHSASLYTRWNGICRDDGNIKSDVFMTQFSAL
QTARSVRTRRLAAAEENIEVARAARLAQIFKEICDGIISYKDSSRQALAAPLLNLPPKKKNADYYEKISDPLDLITIEKQILTGYYKTVE
AFDADMLKVFRNAEKYYGRKSPVGRDVCRLRKAYYNARHEASAQIDEIVGETASEADSSETSVSEKENGHEKDDDVIRCICGLYKDEGLM
IQCDKCMVWQHCDCMGVNSDVEHYLCEQCDPRPVDREVPMIPRPHYAQPGCVYFICLLRDDLLLRQGDCVYLMRDSRRTPDGHPVRQSYR
LLSHINRDKLDIFRIEKLWKNEKEERFAFGHHYFRPHETHHSPSRRFYHNELFRVPLYEIIPLEAVVGTCCVLDLYTYCKGRPKGVKEQD
VYICDYRLDKSAHLFYKIHRNRYPVCTKPYAFDHFPKKLTPKKDFSPHYVPDNYKRNGGRSSWKSERSKPPLKDLGQEDDALPLIEEVLA
SQEQAANEIPSLEEPEREGATANVSEGEKKTEESSQEPQSTCTPEERRHNQRERLNQILLNLLEKIPGKNAIDVTYLLEEGSGRKLRRRT

--------------------------------------------------------------
>59665_59665_2_NOS1AP-ASH1L_NOS1AP_chr1_162257226_ENST00000361897_ASH1L_chr1_155452240_ENST00000392403_length(transcript)=10752nt_BP=672nt
CGTCGCCTTTTCTTCTTCGTCCCGGGCGGTGCGTTCCACTGCTCTGGGGCCGGCGCCGCGCCCAGTCCCGCTTCGGGCCGCAAGCCCCAC
CGCTCCCCTCCCCGGGCAGGGGCGCCGCGCAGCCCGCTCCCGCCGCCACCTCCTCCCCTGCCGCCCTCCTAGCCGGCAGGAATTGCGCGA
CCACAGCGCCGCTCGCGTCGCCCGCATCAGCTCAGCCCGCTGCCGCTCGGCCCTCGGCACCGCTCCGGGTCCGGCCGCCGCGCGGCCAGG
GCTCCCCCTGCCCAGCGCTCCCAGGCCCCGCCACGCGTCGCCGCGCCCAGCTCCAGTCTCCCCTCCCCGGGGTCTCGCCAGCCCCTTCCT
GCAGCCGCCGCCTCCGAAGGAGCGGGTCCGCCGCGGGTAACCATGCCTAGCAAAACCAAGTACAACCTTGTGGACGATGGGCACGACCTG
CGGATCCCCTTGCACAACGAGGACGCCTTCCAGCACGGCATCTGCTTTGAGGCCAAGTACGTAGGAAGCCTGGACGTGCCAAGGCCCAAC
AGCAGGGTGGAGATCGTGGCTGCCATGCGCCGGATACGGTATGAGTTTAAAGCCAAGAACATCAAGAAGAAGAAAGTGAGCATTATGGTT
TCAGTGGATGGAGTGAAAGTGATTCTGAAGAAGAAGAAAAAGGACCCTTCAAAGTTGTACAAGAAAGCAGATGATGTTGCAGCCATTGAA
TGCCAGTCTGAAGAAGTCATCCGTCTTCATTCACAGGGAGAAAACAATCCTTTGTCTAAGAAGCTGTCTCCAGTACACTCAGAAATGGCA
GATTATATTAATGCAACGCCATCTACTCTTCTTGGTAGCCGGGATCCTGATTTAAAGGACAGAGCATTACTTAATGGAGGAACTAGTGTA
ACAGAAAAGTTGGCACAGCTGATTGCTACCTGTCCTCCTTCCAAGTCTTCCAAGACAAAACCGAAGAAGTTAGGAACTGGCACTACAGCA
GGATTGGTTAGCAAGGATTTGATCAGGAAAGCAGGTGTTGGCTCTGTAGCTGGAATAATACATAAGGACTTAATAAAAAAGCCAACCATC
AGCACAGCAGTTGGATTGGTAACTAAAGATCCTGGGAAAAAGCCAGTGTTTAATGCAGCAGTAGGATTGGTCAATAAGGACTCTGTGAAA
AAACTGGGAACTGGCACTACAGCGGTATTCATTAATAAAAACTTAGGCAAAAAGCCAGGAACTATCACTACAGTAGGACTGCTAAGCAAA
GATTCAGGAAAGAAGCTAGGAATTGGTATTGTTCCAGGTTTAGTGCATAAAGAGTCTGGCAAGAAGTTAGGACTTGGCACTGTGGTTGGA
CTGGTTAATAAAGATTTGGGAAAGAAATTGGGTTCTACTGTTGGCCTAGTGGCCAAGGACTGTGCAAAGAAGATTGTAGCAAGTTCAGCA
ATGGGATTGGTTAATAAGGACATTGGAAAGAAACTAATGAGTTGTCCTTTGGCAGGTCTGATCAGTAAAGATGCCATAAACCTTAAAGCC
GAAGCACTGCTCCCCACTCAGGAACCGCTTAAGGCTTCTTGTAGTACAAACATCAATAATCAGGAAAGTCAGGAACTTTCTGAATCCCTG
AAAGATAGTGCCACCAGCAAAACTTTTGAAAAGAATGTTGTACGGCAGAATAAAGAAAGCATATTGGAAAAGTTCTCAGTACGAAAAGAA
ATCATTAATTTGGAGAAAGAAATGTTTAATGAAGGAACATGCATTCAGCAAGACAGTTTCTCATCCAGTGAAAAGGGATCTTATGAAACC
TCAAAGCATGAAAAGCAGCCTCCTGTATATTGCACTTCTCCGGACTTTAAAATGGGAGGTGCTTCTGATGTATCTACCGCTAAATCCCCA
TTCAGTGCAGTAGGAGAAAGCAATCTCCCTTCCCCATCACCTACTGTATCTGTTAATCCTTTAACCAGAAGTCCCCCTGAAACTTCTTCA
CAGTTGGCTCCTAATCCATTACTTTTAAGTTCTACTACAGAACTAATCGAAGAAATTTCTGAATCTGTTGGAAAGAACCAGTTTACTTCT
GAAAGTACCCACTTGAACGTTGGTCATAGGTCAGTTGGTCATAGTATAAGTATTGAATGTAAAGGGATTGATAAAGAGGTAAATGATTCA
AAAACTACCCATATAGATATTCCAAGAATAAGCTCTTCCCTTGGAAAAAAGCCAAGTTTGACTTCTGAATCCAGCATTCATACTATTACT
CCTTCAGTTGTTAACTTCACTAGTTTATTTAGTAATAAGCCTTTTTTAAAACTGGGTGCAGTATCTGCATCAGACAAACACTGCCAAGTT
GCTGAAAGCCTAAGTACTAGTTTGCAGTCCAAACCATTAAAAAAAAGAAAAGGAAGAAAACCTCGGTGGACTAAAGTGGTGGCAAGAAGC
ACATGCCGGTCTCCAAAAGGGCTAGAATTAGAAAGATCAGAGCTTTTTAAAAACGTTTCATGTAGCTCACTATCAAATAGTAATTCTGAG
CCAGCCAAGTTTATGAAAAACATTGGACCCCCTTCATTTGTAGATCATGACTTCCTTAAACGCCGATTGCCAAAGTTGAGCAAATCCACA
GCTCCATCTCTTGCTCTCTTAGCTGATAGTGAAAAACCATCTCATAAGTCTTTTGCTACTCACAAACTATCCTCCAGTATGTGTGTCTCT
AGTGACCTTTTGTCTGATATTTATAAGCCCAAAAGAGGAAGGCCTAAATCTAAGGAGATGCCTCAACTGGAAGGGCCACCTAAAAGGACT
TTAAAAATCCCTGCTTCTAAAGTGTTTTCTTTACAGTCTAAGGAAGAACAAGAACCCCCAATTTTACAGCCAGAAATTGAAATCCCTTCC
TTCAAACAAGGTCTGTCTGTGTCTCCTTTTCCAAAAAAGAGAGGCAGGCCTAAGAGGCAAATGAGGTCACCAGTCAAGATGAAGCCACCT
GTACTGTCAGTGGCTCCATTTGTTGCCACTGAAAGTCCAAGCAAGCTAGAATCTGAAAGTGACAACCATAGAAGTAGCAGTGATTTCTTT
GAGAGCGAGGATCAACTTCAGGATCCAGATGACCTAGATGACAGTCATAGGCCAAGTGTCTGTAGTATGAGTGACCTTGAGATGGAACCA
GATAAAAAAATTACCAAGAGAAACAATGGACAATTAATGAAAACAATTATCCGCAAAATAAATAAAATGAAGACTTTAAAGAGAAAGAAA
CTGTTGAATCAGATTCTTTCAAGTTCTGTAGAATCAAGTAATAAAGGGAAAGTGCAATCCAAACTCCATAATACGGTATCAAGTCTTGCT
GCCACATTTGGCTCTAAATTGGGCCAACAGATAAATGTCAGCAAGAAAGGAACCATTTATATAGGAAAGAGAAGAGGTCGCAAACCAAAA
ACTGTCTTAAATGGTATTCTTTCTGGTAGTCCTACTAGCCTTGCTGTTCTTGAGCAAACAGCTCAACAGGCAGCTGGGTCAGCATTAGGA
CAGATTCTTCCCCCATTACTGCCTTCATCTGCTAGTAGTTCTGAGATTCTTCCATCACCTATTTGCTCTCAGTCTTCTGGGACTAGTGGA
GGTCAGAGCCCTGTAAGTAGTGATGCAGGTTTTGTTGAACCCAGTTCAGTGCCATATTTGCATTTACACTCCAGACAGGGCAGTATGATT
CAGACTCTTGCAATGAAGAAGGCCTCAAAGGGGAGGAGGCGGTTATCTCCTCCTACTTTGTTGCCAAATTCTCCTTCGCACTTGAGTGAA
CTCACATCTCTAAAAGAAGCTACTCCTTCCCCAATCAGTGAGTCTCATAGTGATGAGACCATTCCCAGTGATAGTGGAATTGGAACAGAT
AATAACAGCACATCAGACAGGGCAGAGAAATTTTGTGGGCAAAAAAAGAGGAGGCATTCTTTTGAGCATGTTTCTCTGATTCCCCCTGAA
ACCTCTACAGTGCTAAGCAGTCTTAAAGAAAAACATAAACACAAATGTAAGCGCAGGAATCATGATTACCTCAGCTATGACAAGATGAAA
AGGCAGAAACGAAAACGGAAAAAGAAATATCCCCAGCTTCGAAATAGACAGGATCCAGACTTTATTGCAGAGCTGGAGGAACTAATAAGT
CGCCTAAGTGAAATTCGGATCACTCATCGAAGTCATCATTTTATCCCCCGAGATCTTCTGCCAACTATCTTTCGAATCAACTTTAATAGT
TTCTATACACATCCTTCTTTCCCCTTAGACCCTTTGCACTACATTCGAAAACCTGACTTAAAAAAGAAAAGAGGGAGACCCCCTAAGATG
AGGGAGGCAATGGCTGAAATGCCTTTTATGCACAGCCTTAGTTTTCCTCTTTCTAGTACTGGATTCTATCCATCTTATGGTATGCCTTAC
TCTCCTTCACCCCTTACAGCTGCTCCCATAGGATTAGGTTACTATGGAAGGTATCCTCCCACTCTTTATCCACCTCCTCCATCTCCTTCT
TTCACCACGCCACTTCCACCTCCTTCCTATATGCATGCTGGTCATTTACTTCTCAATCCTGCCAAATACCATAAGAAAAAGCATAAGCTA
CTTCGACAGGAGGCCTTTCTTACAACCAGCAGGACTCCCCTCCTTTCCATGAGTACCTACCCCAGTGTTCCTCCTGAGATGGCCTATGGT
TGGATGGTTGAGCACAAACACAGGCACCGTCACAAACACAGAGAACACCGTTCTTCTGAACAACCCCAGGTTTCTATGGACACTGGCTCT
TCCCGATCTGTCCTGGAATCTTTGAAGCGCTATAGATTTGGAAAGGATGCTGTTGGAGAGCGATATAAGCATAAGGAAAAGCACCGTTGT
CACATGTCCTGCCCTCATCTCTCTCCTTCAAAAAGCTTAATAAACAGAGAGGAACAGTGGGTCCACCGAGAGCCTTCAGAATCTAGTCCA
TTGGCCTTGGGATTGCAGACACCTTTACAGATTGACTGTTCAGAAAGTTCTCCAAGCTTATCCCTTGGAGGATTCACTCCCAACTCTGAG
CCAGCCAGCAGTGATGAACATACAAACCTTTTCACAAGTGCAATAGGCAGCTGCAGAGTTTCAAACCCTAACTCCAGTGGCCGGAAGAAA
TTAACTGACAGCCCTGGACTCTTTTCTGCACAGGACACTTCACTAAATCGGCTTCACAGAAAGGAGTCACTGCCTTCTAACGAAAGGGCA
GTACAGACTTTGGCAGGCTCCCAGCCAACCTCTGATAAACCCTCCCAGCGGCCATCAGAGAGCACAAATTGTAGCCCTACCCGGAAAAGG
TCTTCATCTGAGAGTACTTCTTCAACAGTAAACGGAGTTCCCTCTCGAAGTCCAAGATTAGTTGCTTCTGGGGATGACTCTGTGGATAGT
CTGCTGCAGCGGATGGTACAAAATGAGGACCAAGAGCCCATGGAGAAAAGTATTGATGCTGTGATTGCAACTGCCTCTGCACCACCTTCT
TCCAGTCCAGGCCGTAGCCACAGCAAGGACCGAACCCTGGGAAAACCAGACAGCCTTTTAGTGCCTGCAGTCACAAGTGACTCTTGCAAT
AATAGCATCTCACTCCTATCTGAAAAGTTGACAAGCAGCTGTTCCCCCCATCATATCAAGAGAAGTGTAGTGGAAGCTATGCAACGCCAA
GCTCGGAAAATGTGCAATTACGACAAAATCTTGGCCACAAAGAAAAACCTAGACCATGTCAATAAAATCTTAAAAGCCAAAAAACTTCAA
AGGCAGGCCAGGACAGGGAATAACTTTGTGAAACGTAGGCCAGGTCGACCTCGGAAATGTCCCCTTCAGGCTGTCGTATCAATGCAAGCA
TTCCAGGCTGCTCAGTTTGTCAACCCAGAATTGAACAGAGACGAGGAAGGAGCAGCACTGCACCTCAGTCCTGACACAGTTACAGATGTA
ATTGAGGCTGTTGTTCAGAGTGTAAATCTGAACCCAGAACATAAAAAGGGGTTGAAGAGAAAAGGTTGGCTATTGGAAGAACAGACCAGA
AAAAAGCAGAAGCCATTACCAGAGGAAGAAGAGCAAGAGAATAATAAAAGCTTTAATGAAGCACCAGTTGAGATTCCCAGTCCTTCTGAA
ACCCCAGCTAAACCTTCTGAACCTGAAAGTACCTTGCAGCCTGTGCTTTCTCTCATCCCAAGGGAAAAGAAGCCCCCACGTCCCCCAAAG
AAGAAGTATCAGAAAGCAGGGCTGTATTCTGACGTTTACAAAACTACAGACCCAAAGAGTCGATTGATCCAATTAAAGAAAGAGAAGCTG
GAGTATACTCCAGGAGAGCATGAATATGGATTATTTCCAGCGCCCATTCATGTTGGAAAGTATCTAAGACAAAAGAGAATTGACTTCCAG
CTTCCTTATGATATCCTTTGGCAGTGGAAACACAATCAGCTATACAAAAAGCCAGATGTCCCACTATATAAGAAAATTCGTTCAAATGTC
TACGTTGATGTCAAACCCCTTTCTGGTTACGAAGCTACCACCTGTAACTGTAAGAAGCCAGATGATGACACCAGGAAGGGCTGTGTTGAT
GACTGCCTCAATAGAATGATCTTTGCTGAGTGTTCCCCCAACACTTGCCCATGTGGCGAGCAATGCTGTAACCAGAGGATACAGAGGCAT
GAATGGGTGCAATGTCTAGAACGATTTCGAGCTGAGGAAAAAGGTTGGGGAATCAGAACCAAAGAGCCCCTAAAAGCTGGGCAGTTCATC
ATTGAATACCTAGGGGAGGTCGTCAGTGAACAGGAGTTCAGGAACAGGATGATTGAGCAGTATCATAATCACAGTGACCACTACTGCCTG
AACCTGGATAGTGGGATGGTGATTGACAGTTACCGCATGGGAAATGAGGCCCGATTCATCAACCATAGCTGTGACCCAAATTGTGAAATG
CAGAAATGGTCTGTTAATGGAGTATACCGGATTGGACTCTATGCTCTTAAAGACATGCCAGCTGGGACTGAACTCACTTATGATTATAAC
TTTCATTCCTTCAATGTGGAAAAACAGCAACTTTGTAAGTGTGGCTTTGAGAAATGTCGAGGAATCATCGGAGGCAAGAGTCAGCGTGTG
AATGGACTCACCAGCAGCAAAAACAGCCAGCCCATGGCCACACACAAAAAATCTGGACGGTCAAAAGAGAAGAGAAAGTCTAAGCACAAG
CTGAAGAAAAGGAGAGGCCATCTCTCTGAGGAACCCAGTGAAAATATCAACACCCCAACTAGATTGACCCCCCAATTACAGATGAAGCCA
ATGTCCAATCGTGAAAGGAACTTTGTGTTAAAGCATCATGTATTCTTGGTCCGAAACTGGGAGAAGATTCGTCAAAAACAGGAGGAAGTA
AAGCACACCAGTGATAATATTCACTCAGCATCATTATATACCCGTTGGAATGGGATCTGCCGAGATGATGGGAATATCAAGTCTGATGTC
TTCATGACCCAGTTCTCTGCCCTGCAGACAGCTCGATCTGTTCGAACAAGACGGTTGGCAGCTGCAGAGGAAAATATTGAAGTGGCTCGG
GCAGCCCGCCTAGCCCAGATCTTCAAAGAAATTTGTGATGGTATCATCTCTTATAAAGATTCTTCCCGGCAAGCACTGGCAGCTCCACTT
TTGAACCTTCCCCCAAAGAAAAAGAATGCTGATTATTATGAGAAGATCTCTGATCCCCTAGATCTTATCACCATAGAGAAGCAGATCCTC
ACTGGTTACTATAAGACAGTGGAAGCTTTTGATGCTGACATGCTCAAAGTCTTTCGGAATGCTGAGAAGTACTATGGGCGTAAATCCCCA
GTTGGGAGAGATGTTTGTCGTCTACGAAAGGCCTATTACAATGCCCGGCATGAGGCATCAGCCCAGATTGATGAGATTGTGGGAGAGACA
GCAAGTGAGGCAGACAGCAGTGAGACCTCAGTCTCTGAAAAGGAGAATGGGCATGAGAAGGACGACGATGTTATTCGCTGTATCTGTGGC
CTCTACAAGGATGAAGGTCTCATGATCCAGTGTGACAAGTGCATGGTATGGCAGCACTGTGATTGTATGGGAGTGAACTCAGATGTGGAG
CACTACCTTTGTGAGCAGTGTGACCCAAGGCCTGTGGACAGGGAGGTTCCCATGATCCCTCGGCCCCACTATGCCCAACCTGGCTGTGTC
TACTTCATCTGTTTGCTCCGAGATGACTTGCTGCTTCGTCAGGGTGACTGTGTGTATCTGATGAGGGATAGTCGGCGCACCCCTGATGGC
CACCCGGTCCGTCAGTCCTATCGACTGTTATCTCACATTAACCGAGATAAACTTGACATCTTTCGCATTGAGAAGCTTTGGAAGAATGAA
AAAGAGGAACGGTTTGCCTTTGGTCACCATTATTTCCGTCCCCACGAAACACACCACTCTCCATCCCGTCGGTTCTATCATAATGAACTA
TTTCGGGTGCCACTCTATGAGATCATTCCCTTGGAGGCTGTAGTGGGGACCTGCTGTGTGTTGGACCTTTATACGTATTGTAAAGGGAGA
CCCAAAGGAGTAAAGGAGCAAGATGTGTACATCTGTGATTATCGGCTTGACAAGTCAGCACACCTGTTTTACAAGATCCACCGGAACCGC
TATCCTGTCTGCACCAAACCCTATGCTTTTGATCACTTCCCCAAGAAGCTCACTCCCAAAAAAGATTTCTCGCCTCATTACGTCCCAGAC
AACTACAAGAGGAATGGAGGACGATCATCCTGGAAGTCTGAGCGCTCAAAGCCACCCCTAAAAGACTTGGGCCAGGAGGATGATGCTCTA
CCCTTGATTGAAGAGGTTCTAGCCAGTCAAGAGCAAGCAGCCAATGAGATACCCAGCCTGGAGGAGCCAGAACGGGAAGGGGCCACTGCT
AACGTCAGTGAGGGTGAAAAAAAAACAGAGGAAAGTAGTCAAGAACCCCAGTCAACCTGTACCCCTGAGGAACGACGGCATAACCAACGG
GAACGACTCAACCAGATCTTGCTCAATCTCCTTGAAAAAATCCCTGGAAAAAATGCCATTGATGTGACCTACTTGCTGGAGGAAGGATCA
GGCAGGAAACTGCGAAGGCGTACTTTGTTTATCCCAGAAAACAGCTTTCGAAAGTGACCCTCAAAGAATGAGAACCTCAAGCATCTGGGA
TCCAGTGGAGCTAATCAGTCCTGCCTCCTGCTCTCTGGGTATAGACAGGGGTGGGAAGGGTCCATCTGGGCAAGGGGAATGGGGCCATGT
TGTTGACATTAGGTACTTAATAAGCCTTGGAGCTAGTGGAGAGGGAGAGGAAAGGGTTCTGTCCAAGACAGTTCAGGTTAATTAATTTTC
TTCTCCATTGCTTCACCTTAAGGGTTAATAATGTAGAGAGGAGGGAGGACCACATTGATGACCAGAACCTACTGGTACTTTATAGCATTT
GCCCCACCCCACAGCTTAGGTTTTTCTGTCATCCTCAGATCCCACAGGCATTGCGAAGAAGCTGCTTCCTATACCCAGGTATAACTCAAA
ATCCAAAGGGATAGGGCCAGGATCCCTATTCCTACCCCATCTATTCTCTGTTGGCTCCAAGAGCTACCCCAGAGACCTTAAACAGAAACA
GTAGCTGAGGCTTCTTCCTAGATACCTGACTAGGGAAGTTTGTCTCTCCTTTCTTGCCCAACCAGGTCAAAGTAAAATGTGAGTTGACAG
CTCAAAGCACTTGTAACTGCTGCCCCCTCCCTACCTCTACTCCCCAAAATGGAATCATGGGATAGGGAAGGCCCCCATGGGGTCAGAAGG
GCACGGTAGTTCTTGCAATTATTTTTGTTTTACCCTTCATAACCTGTCAAACATATTTTTTTCTAATGAGAAAGCCAGGCCCCCGCCAGC
ACACATGCTGTTTTTAATGCGCTGTAGTTCTTGTGTGTCTGCTGTGCTGTGCAAATGGAGATTCAGTTCAAAATAAAATCATTTAAAAAC
CTACATAAAAAGAACTCTAAACCCACCCCTGCAACAAAAGTCACTACATAAACTGTTCAGCAGTATTCACCTATCAGAGTATTTGTTGTG
AGTATAGATTATCAATTGAAAACACTACTCTTGTTTTCTTAATTGTACAGTTTTCAATGTCCCTTTCTTAAAGAGACAGTATATTTCTCT
TCACCCCTAGCCCATCTTCCCTCACCCTCCTGAATGACATCAGGAGGTATATCCAGGGTGTCTCCTTCCTTCCTACTCTCTTGACCAGAA
GTTAACAGACTATACTGTCTCTTTAAAAATAAAATTTAAAAAGCTTTGTTGTCTTTTCAGACATACATATGCATATATGTTTTAGATGTT
CTTATAAGAGAAAAGATGGTTTTTAAATGTGCCAAGTTGTGTGTGTGTGTGTATATATATGTGTGTATGTGTGTGTATATATATATGTGT
GTGTGTATATATATACACACACACACACACACCTGCTGTGTGATTGGTAAGCAATACAATAGTAAACATGTCCCCATTACTTTTTTCTAA
TATTGGACCAATGCTGTCCTAATTGTACATTTCCCCTTATGGTGACGATGCTCTGACTCGTTTAGGTAGACACATTGACCACCTTCCATT
CCATTAAATATTTTTTCCTTTTTCCCCTTTCTGTGTCATTCTTGAGGAAAAAACAAAAGAGAGAGGGGATGCCAATGATCCCCTTGAGCA

>59665_59665_2_NOS1AP-ASH1L_NOS1AP_chr1_162257226_ENST00000361897_ASH1L_chr1_155452240_ENST00000392403_length(amino acids)=2975AA_BP=151
MPLGPRHRSGSGRRAARAPPAQRSQAPPRVAAPSSSLPSPGSRQPLPAAAASEGAGPPRVTMPSKTKYNLVDDGHDLRIPLHNEDAFQHG
ICFEAKYVGSLDVPRPNSRVEIVAAMRRIRYEFKAKNIKKKKVSIMVSVDGVKVILKKKKKDPSKLYKKADDVAAIECQSEEVIRLHSQG
ENNPLSKKLSPVHSEMADYINATPSTLLGSRDPDLKDRALLNGGTSVTEKLAQLIATCPPSKSSKTKPKKLGTGTTAGLVSKDLIRKAGV
GSVAGIIHKDLIKKPTISTAVGLVTKDPGKKPVFNAAVGLVNKDSVKKLGTGTTAVFINKNLGKKPGTITTVGLLSKDSGKKLGIGIVPG
LVHKESGKKLGLGTVVGLVNKDLGKKLGSTVGLVAKDCAKKIVASSAMGLVNKDIGKKLMSCPLAGLISKDAINLKAEALLPTQEPLKAS
CSTNINNQESQELSESLKDSATSKTFEKNVVRQNKESILEKFSVRKEIINLEKEMFNEGTCIQQDSFSSSEKGSYETSKHEKQPPVYCTS
PDFKMGGASDVSTAKSPFSAVGESNLPSPSPTVSVNPLTRSPPETSSQLAPNPLLLSSTTELIEEISESVGKNQFTSESTHLNVGHRSVG
HSISIECKGIDKEVNDSKTTHIDIPRISSSLGKKPSLTSESSIHTITPSVVNFTSLFSNKPFLKLGAVSASDKHCQVAESLSTSLQSKPL
KKRKGRKPRWTKVVARSTCRSPKGLELERSELFKNVSCSSLSNSNSEPAKFMKNIGPPSFVDHDFLKRRLPKLSKSTAPSLALLADSEKP
SHKSFATHKLSSSMCVSSDLLSDIYKPKRGRPKSKEMPQLEGPPKRTLKIPASKVFSLQSKEEQEPPILQPEIEIPSFKQGLSVSPFPKK
RGRPKRQMRSPVKMKPPVLSVAPFVATESPSKLESESDNHRSSSDFFESEDQLQDPDDLDDSHRPSVCSMSDLEMEPDKKITKRNNGQLM
KTIIRKINKMKTLKRKKLLNQILSSSVESSNKGKVQSKLHNTVSSLAATFGSKLGQQINVSKKGTIYIGKRRGRKPKTVLNGILSGSPTS
LAVLEQTAQQAAGSALGQILPPLLPSSASSSEILPSPICSQSSGTSGGQSPVSSDAGFVEPSSVPYLHLHSRQGSMIQTLAMKKASKGRR
RLSPPTLLPNSPSHLSELTSLKEATPSPISESHSDETIPSDSGIGTDNNSTSDRAEKFCGQKKRRHSFEHVSLIPPETSTVLSSLKEKHK
HKCKRRNHDYLSYDKMKRQKRKRKKKYPQLRNRQDPDFIAELEELISRLSEIRITHRSHHFIPRDLLPTIFRINFNSFYTHPSFPLDPLH
YIRKPDLKKKRGRPPKMREAMAEMPFMHSLSFPLSSTGFYPSYGMPYSPSPLTAAPIGLGYYGRYPPTLYPPPPSPSFTTPLPPPSYMHA
GHLLLNPAKYHKKKHKLLRQEAFLTTSRTPLLSMSTYPSVPPEMAYGWMVEHKHRHRHKHREHRSSEQPQVSMDTGSSRSVLESLKRYRF
GKDAVGERYKHKEKHRCHMSCPHLSPSKSLINREEQWVHREPSESSPLALGLQTPLQIDCSESSPSLSLGGFTPNSEPASSDEHTNLFTS
AIGSCRVSNPNSSGRKKLTDSPGLFSAQDTSLNRLHRKESLPSNERAVQTLAGSQPTSDKPSQRPSESTNCSPTRKRSSSESTSSTVNGV
PSRSPRLVASGDDSVDSLLQRMVQNEDQEPMEKSIDAVIATASAPPSSSPGRSHSKDRTLGKPDSLLVPAVTSDSCNNSISLLSEKLTSS
CSPHHIKRSVVEAMQRQARKMCNYDKILATKKNLDHVNKILKAKKLQRQARTGNNFVKRRPGRPRKCPLQAVVSMQAFQAAQFVNPELNR
DEEGAALHLSPDTVTDVIEAVVQSVNLNPEHKKGLKRKGWLLEEQTRKKQKPLPEEEEQENNKSFNEAPVEIPSPSETPAKPSEPESTLQ
PVLSLIPREKKPPRPPKKKYQKAGLYSDVYKTTDPKSRLIQLKKEKLEYTPGEHEYGLFPAPIHVGKYLRQKRIDFQLPYDILWQWKHNQ
LYKKPDVPLYKKIRSNVYVDVKPLSGYEATTCNCKKPDDDTRKGCVDDCLNRMIFAECSPNTCPCGEQCCNQRIQRHEWVQCLERFRAEE
KGWGIRTKEPLKAGQFIIEYLGEVVSEQEFRNRMIEQYHNHSDHYCLNLDSGMVIDSYRMGNEARFINHSCDPNCEMQKWSVNGVYRIGL
YALKDMPAGTELTYDYNFHSFNVEKQQLCKCGFEKCRGIIGGKSQRVNGLTSSKNSQPMATHKKSGRSKEKRKSKHKLKKRRGHLSEEPS
ENINTPTRLTPQLQMKPMSNRERNFVLKHHVFLVRNWEKIRQKQEEVKHTSDNIHSASLYTRWNGICRDDGNIKSDVFMTQFSALQTARS
VRTRRLAAAEENIEVARAARLAQIFKEICDGIISYKDSSRQALAAPLLNLPPKKKNADYYEKISDPLDLITIEKQILTGYYKTVEAFDAD
MLKVFRNAEKYYGRKSPVGRDVCRLRKAYYNARHEASAQIDEIVGETASEADSSETSVSEKENGHEKDDDVIRCICGLYKDEGLMIQCDK
CMVWQHCDCMGVNSDVEHYLCEQCDPRPVDREVPMIPRPHYAQPGCVYFICLLRDDLLLRQGDCVYLMRDSRRTPDGHPVRQSYRLLSHI
NRDKLDIFRIEKLWKNEKEERFAFGHHYFRPHETHHSPSRRFYHNELFRVPLYEIIPLEAVVGTCCVLDLYTYCKGRPKGVKEQDVYICD
YRLDKSAHLFYKIHRNRYPVCTKPYAFDHFPKKLTPKKDFSPHYVPDNYKRNGGRSSWKSERSKPPLKDLGQEDDALPLIEEVLASQEQA
ANEIPSLEEPEREGATANVSEGEKKTEESSQEPQSTCTPEERRHNQRERLNQILLNLLEKIPGKNAIDVTYLLEEGSGRKLRRRTLFIPE

--------------------------------------------------------------
>59665_59665_3_NOS1AP-ASH1L_NOS1AP_chr1_162257226_ENST00000530878_ASH1L_chr1_155452240_ENST00000368346_length(transcript)=11556nt_BP=674nt
ACCGTCGCCTTTTCTTCTTCGTCCCGGGCGGTGCGTTCCACTGCTCTGGGGCCGGCGCCGCGCCCAGTCCCGCTTCGGGCCGCAAGCCCC
ACCGCTCCCCTCCCCGGGCAGGGGCGCCGCGCAGCCCGCTCCCGCCGCCACCTCCTCCCCTGCCGCCCTCCTAGCCGGCAGGAATTGCGC
GACCACAGCGCCGCTCGCGTCGCCCGCATCAGCTCAGCCCGCTGCCGCTCGGCCCTCGGCACCGCTCCGGGTCCGGCCGCCGCGCGGCCA
GGGCTCCCCCTGCCCAGCGCTCCCAGGCCCCGCCACGCGTCGCCGCGCCCAGCTCCAGTCTCCCCTCCCCGGGGTCTCGCCAGCCCCTTC
CTGCAGCCGCCGCCTCCGAAGGAGCGGGTCCGCCGCGGGTAACCATGCCTAGCAAAACCAAGTACAACCTTGTGGACGATGGGCACGACC
TGCGGATCCCCTTGCACAACGAGGACGCCTTCCAGCACGGCATCTGCTTTGAGGCCAAGTACGTAGGAAGCCTGGACGTGCCAAGGCCCA
ACAGCAGGGTGGAGATCGTGGCTGCCATGCGCCGGATACGGTATGAGTTTAAAGCCAAGAACATCAAGAAGAAGAAAGTGAGCATTATGG
TTTCAGTGGATGGAGTGAAAGTGATTCTGAAGAAGAAGAAAAAGGACCCTTCAAAGTTGTACAAGAAAGCAGATGATGTTGCAGCCATTG
AATGCCAGTCTGAAGAAGTCATCCGTCTTCATTCACAGGGAGAAAACAATCCTTTGTCTAAGAAGCTGTCTCCAGTACACTCAGAAATGG
CAGATTATATTAATGCAACGCCATCTACTCTTCTTGGTAGCCGGGATCCTGATTTAAAGGACAGAGCATTACTTAATGGAGGAACTAGTG
TAACAGAAAAGTTGGCACAGCTGATTGCTACCTGTCCTCCTTCCAAGTCTTCCAAGACAAAACCGAAGAAGTTAGGAACTGGCACTACAG
CAGGATTGGTTAGCAAGGATTTGATCAGGAAAGCAGGTGTTGGCTCTGTAGCTGGAATAATACATAAGGACTTAATAAAAAAGCCAACCA
TCAGCACAGCAGTTGGATTGGTAACTAAAGATCCTGGGAAAAAGCCAGTGTTTAATGCAGCAGTAGGATTGGTCAATAAGGACTCTGTGA
AAAAACTGGGAACTGGCACTACAGCGGTATTCATTAATAAAAACTTAGGCAAAAAGCCAGGAACTATCACTACAGTAGGACTGCTAAGCA
AAGATTCAGGAAAGAAGCTAGGAATTGGTATTGTTCCAGGTTTAGTGCATAAAGAGTCTGGCAAGAAGTTAGGACTTGGCACTGTGGTTG
GACTGGTTAATAAAGATTTGGGAAAGAAATTGGGTTCTACTGTTGGCCTAGTGGCCAAGGACTGTGCAAAGAAGATTGTAGCAAGTTCAG
CAATGGGATTGGTTAATAAGGACATTGGAAAGAAACTAATGAGTTGTCCTTTGGCAGGTCTGATCAGTAAAGATGCCATAAACCTTAAAG
CCGAAGCACTGCTCCCCACTCAGGAACCGCTTAAGGCTTCTTGTAGTACAAACATCAATAATCAGGAAAGTCAGGAACTTTCTGAATCCC
TGAAAGATAGTGCCACCAGCAAAACTTTTGAAAAGAATGTTGTACGGCAGAATAAAGAAAGCATATTGGAAAAGTTCTCAGTACGAAAAG
AAATCATTAATTTGGAGAAAGAAATGTTTAATGAAGGAACATGCATTCAGCAAGACAGTTTCTCATCCAGTGAAAAGGGATCTTATGAAA
CCTCAAAGCATGAAAAGCAGCCTCCTGTATATTGCACTTCTCCGGACTTTAAAATGGGAGGTGCTTCTGATGTATCTACCGCTAAATCCC
CATTCAGTGCAGTAGGAGAAAGCAATCTCCCTTCCCCATCACCTACTGTATCTGTTAATCCTTTAACCAGAAGTCCCCCTGAAACTTCTT
CACAGTTGGCTCCTAATCCATTACTTTTAAGTTCTACTACAGAACTAATCGAAGAAATTTCTGAATCTGTTGGAAAGAACCAGTTTACTT
CTGAAAGTACCCACTTGAACGTTGGTCATAGGTCAGTTGGTCATAGTATAAGTATTGAATGTAAAGGGATTGATAAAGAGGTAAATGATT
CAAAAACTACCCATATAGATATTCCAAGAATAAGCTCTTCCCTTGGAAAAAAGCCAAGTTTGACTTCTGAATCCAGCATTCATACTATTA
CTCCTTCAGTTGTTAACTTCACTAGTTTATTTAGTAATAAGCCTTTTTTAAAACTGGGTGCAGTATCTGCATCAGACAAACACTGCCAAG
TTGCTGAAAGCCTAAGTACTAGTTTGCAGTCCAAACCATTAAAAAAAAGAAAAGGAAGAAAACCTCGGTGGACTAAAGTGGTGGCAAGAA
GCACATGCCGGTCTCCAAAAGGGCTAGAATTAGAAAGATCAGAGCTTTTTAAAAACGTTTCATGTAGCTCACTATCAAATAGTAATTCTG
AGCCAGCCAAGTTTATGAAAAACATTGGACCCCCTTCATTTGTAGATCATGACTTCCTTAAACGCCGATTGCCAAAGTTGAGCAAATCCA
CAGCTCCATCTCTTGCTCTCTTAGCTGATAGTGAAAAACCATCTCATAAGTCTTTTGCTACTCACAAACTATCCTCCAGTATGTGTGTCT
CTAGTGACCTTTTGTCTGATATTTATAAGCCCAAAAGAGGAAGGCCTAAATCTAAGGAGATGCCTCAACTGGAAGGGCCACCTAAAAGGA
CTTTAAAAATCCCTGCTTCTAAAGTGTTTTCTTTACAGTCTAAGGAAGAACAAGAACCCCCAATTTTACAGCCAGAAATTGAAATCCCTT
CCTTCAAACAAGGTCTGTCTGTGTCTCCTTTTCCAAAAAAGAGAGGCAGGCCTAAGAGGCAAATGAGGTCACCAGTCAAGATGAAGCCAC
CTGTACTGTCAGTGGCTCCATTTGTTGCCACTGAAAGTCCAAGCAAGCTAGAATCTGAAAGTGACAACCATAGAAGTAGCAGTGATTTCT
TTGAGAGCGAGGATCAACTTCAGGATCCAGATGACCTAGATGACAGTCATAGGCCAAGTGTCTGTAGTATGAGTGACCTTGAGATGGAAC
CAGATAAAAAAATTACCAAGAGAAACAATGGACAATTAATGAAAACAATTATCCGCAAAATAAATAAAATGAAGACTTTAAAGAGAAAGA
AACTGTTGAATCAGATTCTTTCAAGTTCTGTAGAATCAAGTAATAAAGGGAAAGTGCAATCCAAACTCCATAATACGGTATCAAGTCTTG
CTGCCACATTTGGCTCTAAATTGGGCCAACAGATAAATGTCAGCAAGAAAGGAACCATTTATATAGGAAAGAGAAGAGGTCGCAAACCAA
AAACTGTCTTAAATGGTATTCTTTCTGGTAGTCCTACTAGCCTTGCTGTTCTTGAGCAAACAGCTCAACAGGCAGCTGGGTCAGCATTAG
GACAGATTCTTCCCCCATTACTGCCTTCATCTGCTAGTAGTTCTGAGATTCTTCCATCACCTATTTGCTCTCAGTCTTCTGGGACTAGTG
GAGGTCAGAGCCCTGTAAGTAGTGATGCAGGTTTTGTTGAACCCAGTTCAGTGCCATATTTGCATTTACACTCCAGACAGGGCAGTATGA
TTCAGACTCTTGCAATGAAGAAGGCCTCAAAGGGGAGGAGGCGGTTATCTCCTCCTACTTTGTTGCCAAATTCTCCTTCGCACTTGAGTG
AACTCACATCTCTAAAAGAAGCTACTCCTTCCCCAATCAGTGAGTCTCATAGTGATGAGACCATTCCCAGTGATAGTGGAATTGGAACAG
ATAATAACAGCACATCAGACAGGGCAGAGAAATTTTGTGGGCAAAAAAAGAGGAGGCATTCTTTTGAGCATGTTTCTCTGATTCCCCCTG
AAACCTCTACAGTGCTAAGCAGTCTTAAAGAAAAACATAAACACAAATGTAAGCGCAGGAATCATGATTACCTCAGCTATGACAAGATGA
AAAGGCAGAAACGAAAACGGAAAAAGAAATATCCCCAGCTTCGAAATAGACAGGATCCAGACTTTATTGCAGAGCTGGAGGAACTAATAA
GTCGCCTAAGTGAAATTCGGATCACTCATCGAAGTCATCATTTTATCCCCCGAGATCTTCTGCCAACTATCTTTCGAATCAACTTTAATA
GTTTCTATACACATCCTTCTTTCCCCTTAGACCCTTTGCACTACATTCGAAAACCTGACTTAAAAAAGAAAAGAGGGAGACCCCCTAAGA
TGAGGGAGGCAATGGCTGAAATGCCTTTTATGCACAGCCTTAGTTTTCCTCTTTCTAGTACTGGATTCTATCCATCTTATGGTATGCCTT
ACTCTCCTTCACCCCTTACAGCTGCTCCCATAGGATTAGGTTACTATGGAAGGTATCCTCCCACTCTTTATCCACCTCCTCCATCTCCTT
CTTTCACCACGCCACTTCCACCTCCTTCCTATATGCATGCTGGTCATTTACTTCTCAATCCTGCCAAATACCATAAGAAAAAGCATAAGC
TACTTCGACAGGAGGCCTTTCTTACAACCAGCAGGACTCCCCTCCTTTCCATGAGTACCTACCCCAGTGTTCCTCCTGAGATGGCCTATG
GTTGGATGGTTGAGCACAAACACAGGCACCGTCACAAACACAGAGAACACCGTTCTTCTGAACAACCCCAGGTTTCTATGGACACTGGCT
CTTCCCGATCTGTCCTGGAATCTTTGAAGCGCTATAGATTTGGAAAGGATGCTGTTGGAGAGCGATATAAGCATAAGGAAAAGCACCGTT
GTCACATGTCCTGCCCTCATCTCTCTCCTTCAAAAAGCTTAATAAACAGAGAGGAACAGTGGGTCCACCGAGAGCCTTCAGAATCTAGTC
CATTGGCCTTGGGATTGCAGACACCTTTACAGATTGACTGTTCAGAAAGTTCTCCAAGCTTATCCCTTGGAGGATTCACTCCCAACTCTG
AGCCAGCCAGCAGTGATGAACATACAAACCTTTTCACAAGTGCAATAGGCAGCTGCAGAGTTTCAAACCCTAACTCCAGTGGCCGGAAGA
AATTAACTGACAGCCCTGGACTCTTTTCTGCACAGGACACTTCACTAAATCGGCTTCACAGAAAGGAGTCACTGCCTTCTAACGAAAGGG
CAGTACAGACTTTGGCAGGCTCCCAGCCAACCTCTGATAAACCCTCCCAGCGGCCATCAGAGAGCACAAATTGTAGCCCTACCCGGAAAA
GGTCTTCATCTGAGAGTACTTCTTCAACAGTAAACGGAGTTCCCTCTCGAAGTCCAAGATTAGTTGCTTCTGGGGATGACTCTGTGGATA
GTCTGCTGCAGCGGATGGTACAAAATGAGGACCAAGAGCCCATGGAGAAAAGTATTGATGCTGTGATTGCAACTGCCTCTGCACCACCTT
CTTCCAGTCCAGGCCGTAGCCACAGCAAGGACCGAACCCTGGGAAAACCAGACAGCCTTTTAGTGCCTGCAGTCACAAGTGACTCTTGCA
ATAATAGCATCTCACTCCTATCTGAAAAGTTGACAAGCAGCTGTTCCCCCCATCATATCAAGAGAAGTGTAGTGGAAGCTATGCAACGCC
AAGCTCGGAAAATGTGCAATTACGACAAAATCTTGGCCACAAAGAAAAACCTAGACCATGTCAATAAAATCTTAAAAGCCAAAAAACTTC
AAAGGCAGGCCAGGACAGGGAATAACTTTGTGAAACGTAGGCCAGGTCGACCTCGGAAATGTCCCCTTCAGGCTGTCGTATCAATGCAAG
CATTCCAGGCTGCTCAGTTTGTCAACCCAGAATTGAACAGAGACGAGGAAGGAGCAGCACTGCACCTCAGTCCTGACACAGTTACAGATG
TAATTGAGGCTGTTGTTCAGAGTGTAAATCTGAACCCAGAACATAAAAAGGGGTTGAAGAGAAAAGGTTGGCTATTGGAAGAACAGACCA
GAAAAAAGCAGAAGCCATTACCAGAGGAAGAAGAGCAAGAGAATAATAAAAGCTTTAATGAAGCACCAGTTGAGATTCCCAGTCCTTCTG
AAACCCCAGCTAAACCTTCTGAACCTGAAAGTACCTTGCAGCCTGTGCTTTCTCTCATCCCAAGGGAAAAGAAGCCCCCACGTCCCCCAA
AGAAGAAGTATCAGAAAGCAGGGCTGTATTCTGACGTTTACAAAACTACAGACCCAAAGAGTCGATTGATCCAATTAAAGAAAGAGAAGC
TGGAGTATACTCCAGGAGAGCATGAATATGGATTATTTCCAGCGCCCATTCATGTTGTGTTTTTTGTTTCAGGAAAGTATCTAAGACAAA
AGAGAATTGACTTCCAGCTTCCTTATGATATCCTTTGGCAGTGGAAACACAATCAGCTATACAAAAAGCCAGATGTCCCACTATATAAGA
AAATTCGTTCAAATGTCTACGTTGATGTCAAACCCCTTTCTGGTTACGAAGCTACCACCTGTAACTGTAAGAAGCCAGATGATGACACCA
GGAAGGGCTGTGTTGATGACTGCCTCAATAGAATGATCTTTGCTGAGTGTTCCCCCAACACTTGCCCATGTGGCGAGCAATGCTGTAACC
AGAGGATACAGAGGCATGAATGGGTGCAATGTCTAGAACGATTTCGAGCTGAGGAAAAAGGTTGGGGAATCAGAACCAAAGAGCCCCTAA
AAGCTGGGCAGTTCATCATTGAATACCTAGGGGAGGTCGTCAGTGAACAGGAGTTCAGGAACAGGATGATTGAGCAGTATCATAATCACA
GTGACCACTACTGCCTGAACCTGGATAGTGGGATGGTGATTGACAGTTACCGCATGGGAAATGAGGCCCGATTCATCAACCATAGCTGTG
ACCCAAATTGTGAAATGCAGAAATGGTCTGTTAATGGAGTATACCGGATTGGACTCTATGCTCTTAAAGACATGCCAGCTGGGACTGAAC
TCACTTATGATTATAACTTTCATTCCTTCAATGTGGAAAAACAGCAACTTTGTAAGTGTGGCTTTGAGAAATGTCGAGGAATCATCGGAG
GCAAGAGTCAGCGTGTGAATGGACTCACCAGCAGCAAAAACAGCCAGCCCATGGCCACACACAAAAAATCTGGACGGTCAAAAGAGAAGA
GAAAGTCTAAGCACAAGCTGAAGAAAAGGAGAGGCCATCTCTCTGAGGAACCCAGTGAAAATATCAACACCCCAACTAGATTGACCCCCC
AATTACAGATGAAGCCAATGTCCAATCGTGAAAGGAACTTTGTGTTAAAGCATCATGTATTCTTGGTCCGAAACTGGGAGAAGATTCGTC
AAAAACAGGAGGAAGTAAAGCACACCAGTGATAATATTCACTCAGCATCATTATATACCCGTTGGAATGGGATCTGCCGAGATGATGGGA
ATATCAAGTCTGATGTCTTCATGACCCAGTTCTCTGCCCTGCAGACAGCTCGATCTGTTCGAACAAGACGGTTGGCAGCTGCAGAGGAAA
ATATTGAAGTGGCTCGGGCAGCCCGCCTAGCCCAGATCTTCAAAGAAATTTGTGATGGTATCATCTCTTATAAAGATTCTTCCCGGCAAG
CACTGGCAGCTCCACTTTTGAACCTTCCCCCAAAGAAAAAGAATGCTGATTATTATGAGAAGATCTCTGATCCCCTAGATCTTATCACCA
TAGAGAAGCAGATCCTCACTGGTTACTATAAGACAGTGGAAGCTTTTGATGCTGACATGCTCAAAGTCTTTCGGAATGCTGAGAAGTACT
ATGGGCGTAAATCCCCAGTTGGGAGAGATGTTTGTCGTCTACGAAAGGCCTATTACAATGCCCGGCATGAGGCATCAGCCCAGATTGATG
AGATTGTGGGAGAGACAGCAAGTGAGGCAGACAGCAGTGAGACCTCAGTCTCTGAAAAGGAGAATGGGCATGAGAAGGACGACGATGTTA
TTCGCTGTATCTGTGGCCTCTACAAGGATGAAGGTCTCATGATCCAGTGTGACAAGTGCATGGTATGGCAGCACTGTGATTGTATGGGAG
TGAACTCAGATGTGGAGCACTACCTTTGTGAGCAGTGTGACCCAAGGCCTGTGGACAGGGAGGTTCCCATGATCCCTCGGCCCCACTATG
CCCAACCTGGCTGTGTCTACTTCATCTGTTTGCTCCGAGATGACTTGCTGCTTCGTCAGGGTGACTGTGTGTATCTGATGAGGGATAGTC
GGCGCACCCCTGATGGCCACCCGGTCCGTCAGTCCTATCGACTGTTATCTCACATTAACCGAGATAAACTTGACATCTTTCGCATTGAGA
AGCTTTGGAAGAATGAAAAAGAGGAACGGTTTGCCTTTGGTCACCATTATTTCCGTCCCCACGAAACACACCACTCTCCATCCCGTCGGT
TCTATCATAATGAACTATTTCGGGTGCCACTCTATGAGATCATTCCCTTGGAGGCTGTAGTGGGGACCTGCTGTGTGTTGGACCTTTATA
CGTATTGTAAAGGGAGACCCAAAGGAGTAAAGGAGCAAGATGTGTACATCTGTGATTATCGGCTTGACAAGTCAGCACACCTGTTTTACA
AGATCCACCGGAACCGCTATCCTGTCTGCACCAAACCCTATGCTTTTGATCACTTCCCCAAGAAGCTCACTCCCAAAAAAGATTTCTCGC
CTCATTACGTCCCAGACAACTACAAGAGGAATGGAGGACGATCATCCTGGAAGTCTGAGCGCTCAAAGCCACCCCTAAAAGACTTGGGCC
AGGAGGATGATGCTCTACCCTTGATTGAAGAGGTTCTAGCCAGTCAAGAGCAAGCAGCCAATGAGATACCCAGCCTGGAGGAGCCAGAAC
GGGAAGGGGCCACTGCTAACGTCAGTGAGGGTGAAAAAAAAACAGAGGAAAGTAGTCAAGAACCCCAGTCAACCTGTACCCCTGAGGAAC
GACGGCATAACCAACGGGAACGACTCAACCAGATCTTGCTCAATCTCCTTGAAAAAATCCCTGGAAAAAATGCCATTGATGTGACCTACT
TGCTGGAGGAAGGATCAGGCAGGAAACTGCGAAGGCGTACTTTGTTTATCCCAGAAAACAGCTTTCGAAAGTGACCCTCAAAGAATGAGA
ACCTCAAGCATCTGGGATCCAGTGGAGCTAATCAGTCCTGCCTCCTGCTCTCTGGGTATAGACAGGGGTGGGAAGGGTCCATCTGGGCAA
GGGGAATGGGGCCATGTTGTTGACATTAGGTACTTAATAAGCCTTGGAGCTAGTGGAGAGGGAGAGGAAAGGGTTCTGTCCAAGACAGTT
CAGGTTAATTAATTTTCTTCTCCATTGCTTCACCTTAAGGGTTAATAATGTAGAGAGGAGGGAGGACCACATTGATGACCAGAACCTACT
GGTACTTTATAGCATTTGCCCCACCCCACAGCTTAGGTTTTTCTGTCATCCTCAGATCCCACAGGCATTGCGAAGAAGCTGCTTCCTATA
CCCAGGTATAACTCAAAATCCAAAGGGATAGGGCCAGGATCCCTATTCCTACCCCATCTATTCTCTGTTGGCTCCAAGAGCTACCCCAGA
GACCTTAAACAGAAACAGTAGCTGAGGCTTCTTCCTAGATACCTGACTAGGGAAGTTTGTCTCTCCTTTCTTGCCCAACCAGGTCAAAGT
AAAATGTGAGTTGACAGCTCAAAGCACTTGTAACTGCTGCCCCCTCCCTACCTCTACTCCCCAAAATGGAATCATGGGATAGGGAAGGCC
CCCATGGGGTCAGAAGGGCACGGTAGTTCTTGCAATTATTTTTGTTTTACCCTTCATAACCTGTCAAACATATTTTTTTCTAATGAGAAA
GCCAGGCCCCCGCCAGCACACATGCTGTTTTTAATGCGCTGTAGTTCTTGTGTGTCTGCTGTGCTGTGCAAATGGAGATTCAGTTCAAAA
TAAAATCATTTAAAAACCTACATAAAAAGAACTCTAAACCCACCCCTGCAACAAAAGTCACTACATAAACTGTTCAGCAGTATTCACCTA
TCAGAGTATTTGTTGTGAGTATAGATTATCAATTGAAAACACTACTCTTGTTTTCTTAATTGTACAGTTTTCAATGTCCCTTTCTTAAAG
AGACAGTATATTTCTCTTCACCCCTAGCCCATCTTCCCTCACCCTCCTGAATGACATCAGGAGGTATATCCAGGGTGTCTCCTTCCTTCC
TACTCTCTTGACCAGAAGTTAACAGACTATACTGTCTCTTTAAAAATAAAATTTAAAAAGCTTTGTTGTCTTTTCAGACATACATATGCA
TATATGTTTTAGATGTTCTTATAAGAGAAAAGATGGTTTTTAAATGTGCCAAGTTGTGTGTGTGTGTGTATATATATGTGTGTATGTGTG
TGTATATATATATGTGTGTGTGTATATATATACACACACACACACACACCTGCTGTGTGATTGGTAAGCAATACAATAGTAAACATGTCC
CCATTACTTTTTTCTAATATTGGACCAATGCTGTCCTAATTGTACATTTCCCCTTATGGTGACGATGCTCTGACTCGTTTAGGTAGACAC
ATTGACCACCTTCCATTCCATTAAATATTTTTTCCTTTTTCCCCTTTCTGTGTCATTCTTGAGGAAAAAACAAAAGAGAGAGGGGATGCC
AATGATCCCCTTGAGCAGAGAAAAAGCAAAATAAATATTTTATTAAAGAAAAAAGAGAATTAAGAAAATAGTTTGGAGTATTTTCTTACT
GTAGAGAAGCACTGTACATTACTAAGAGACCTGGGTATAAGATACTCACATGTGGAGCTGGAAAAATCGCATGTCCAAGCCCGTTTGAGT
GGTTTCTTTTGTTTTTCATTGCAGGGAGTGGGTGGGAGGGAGGTGGGACTAGGGGCACTTTGGGGGTCTCCTTTTAGTCAAAAGCGAGAA
AATGACAAGAAAGAGATTAAAATTCAATGTTTCCTTTATAGTGTTAAACACTAAAATTTTAAAAAAGATGAAAAAGAAAAAAAAACTTTG
TAAAATGCGAGAACAGAAGCAAAAGACACTACGCTCTGTCATTTTATCTTTCTTTTGTTGAAAGACTAAAAAAAAACTGAAATGTTTTTT
AGACAATCAAATGTTAGGTAAGTGCAAAAACTTGTTTTTTCTTACTGGTGTAGAAATTAATGCCTTTTTTTATTTTTCAGTTATTTTATA
ATAACGAAATAAAAAGAACCCCCCAGCTGCCAGGCGGGTTTTGGTGTTTGAAATGCGGGGCAAAGCACTACATCACTGCAAATAGATACA
GAGTTAGTCTGCATGTCTGTAGGCTGTGTGATTGCGGAAAATATAAATGCTGCTAATATATTTCCTTTTTACAAAAGCATATCTAAATAG
ATGATTGTTTTGATGTTAATCTTTGTAAATTATGTATTACCAATTTTAACATTGGATGTAATTGCATACAAAGCTTGCATCTCAATCCTT

>59665_59665_3_NOS1AP-ASH1L_NOS1AP_chr1_162257226_ENST00000530878_ASH1L_chr1_155452240_ENST00000368346_length(amino acids)=2980AA_BP=151
MPLGPRHRSGSGRRAARAPPAQRSQAPPRVAAPSSSLPSPGSRQPLPAAAASEGAGPPRVTMPSKTKYNLVDDGHDLRIPLHNEDAFQHG
ICFEAKYVGSLDVPRPNSRVEIVAAMRRIRYEFKAKNIKKKKVSIMVSVDGVKVILKKKKKDPSKLYKKADDVAAIECQSEEVIRLHSQG
ENNPLSKKLSPVHSEMADYINATPSTLLGSRDPDLKDRALLNGGTSVTEKLAQLIATCPPSKSSKTKPKKLGTGTTAGLVSKDLIRKAGV
GSVAGIIHKDLIKKPTISTAVGLVTKDPGKKPVFNAAVGLVNKDSVKKLGTGTTAVFINKNLGKKPGTITTVGLLSKDSGKKLGIGIVPG
LVHKESGKKLGLGTVVGLVNKDLGKKLGSTVGLVAKDCAKKIVASSAMGLVNKDIGKKLMSCPLAGLISKDAINLKAEALLPTQEPLKAS
CSTNINNQESQELSESLKDSATSKTFEKNVVRQNKESILEKFSVRKEIINLEKEMFNEGTCIQQDSFSSSEKGSYETSKHEKQPPVYCTS
PDFKMGGASDVSTAKSPFSAVGESNLPSPSPTVSVNPLTRSPPETSSQLAPNPLLLSSTTELIEEISESVGKNQFTSESTHLNVGHRSVG
HSISIECKGIDKEVNDSKTTHIDIPRISSSLGKKPSLTSESSIHTITPSVVNFTSLFSNKPFLKLGAVSASDKHCQVAESLSTSLQSKPL
KKRKGRKPRWTKVVARSTCRSPKGLELERSELFKNVSCSSLSNSNSEPAKFMKNIGPPSFVDHDFLKRRLPKLSKSTAPSLALLADSEKP
SHKSFATHKLSSSMCVSSDLLSDIYKPKRGRPKSKEMPQLEGPPKRTLKIPASKVFSLQSKEEQEPPILQPEIEIPSFKQGLSVSPFPKK
RGRPKRQMRSPVKMKPPVLSVAPFVATESPSKLESESDNHRSSSDFFESEDQLQDPDDLDDSHRPSVCSMSDLEMEPDKKITKRNNGQLM
KTIIRKINKMKTLKRKKLLNQILSSSVESSNKGKVQSKLHNTVSSLAATFGSKLGQQINVSKKGTIYIGKRRGRKPKTVLNGILSGSPTS
LAVLEQTAQQAAGSALGQILPPLLPSSASSSEILPSPICSQSSGTSGGQSPVSSDAGFVEPSSVPYLHLHSRQGSMIQTLAMKKASKGRR
RLSPPTLLPNSPSHLSELTSLKEATPSPISESHSDETIPSDSGIGTDNNSTSDRAEKFCGQKKRRHSFEHVSLIPPETSTVLSSLKEKHK
HKCKRRNHDYLSYDKMKRQKRKRKKKYPQLRNRQDPDFIAELEELISRLSEIRITHRSHHFIPRDLLPTIFRINFNSFYTHPSFPLDPLH
YIRKPDLKKKRGRPPKMREAMAEMPFMHSLSFPLSSTGFYPSYGMPYSPSPLTAAPIGLGYYGRYPPTLYPPPPSPSFTTPLPPPSYMHA
GHLLLNPAKYHKKKHKLLRQEAFLTTSRTPLLSMSTYPSVPPEMAYGWMVEHKHRHRHKHREHRSSEQPQVSMDTGSSRSVLESLKRYRF
GKDAVGERYKHKEKHRCHMSCPHLSPSKSLINREEQWVHREPSESSPLALGLQTPLQIDCSESSPSLSLGGFTPNSEPASSDEHTNLFTS
AIGSCRVSNPNSSGRKKLTDSPGLFSAQDTSLNRLHRKESLPSNERAVQTLAGSQPTSDKPSQRPSESTNCSPTRKRSSSESTSSTVNGV
PSRSPRLVASGDDSVDSLLQRMVQNEDQEPMEKSIDAVIATASAPPSSSPGRSHSKDRTLGKPDSLLVPAVTSDSCNNSISLLSEKLTSS
CSPHHIKRSVVEAMQRQARKMCNYDKILATKKNLDHVNKILKAKKLQRQARTGNNFVKRRPGRPRKCPLQAVVSMQAFQAAQFVNPELNR
DEEGAALHLSPDTVTDVIEAVVQSVNLNPEHKKGLKRKGWLLEEQTRKKQKPLPEEEEQENNKSFNEAPVEIPSPSETPAKPSEPESTLQ
PVLSLIPREKKPPRPPKKKYQKAGLYSDVYKTTDPKSRLIQLKKEKLEYTPGEHEYGLFPAPIHVVFFVSGKYLRQKRIDFQLPYDILWQ
WKHNQLYKKPDVPLYKKIRSNVYVDVKPLSGYEATTCNCKKPDDDTRKGCVDDCLNRMIFAECSPNTCPCGEQCCNQRIQRHEWVQCLER
FRAEEKGWGIRTKEPLKAGQFIIEYLGEVVSEQEFRNRMIEQYHNHSDHYCLNLDSGMVIDSYRMGNEARFINHSCDPNCEMQKWSVNGV
YRIGLYALKDMPAGTELTYDYNFHSFNVEKQQLCKCGFEKCRGIIGGKSQRVNGLTSSKNSQPMATHKKSGRSKEKRKSKHKLKKRRGHL
SEEPSENINTPTRLTPQLQMKPMSNRERNFVLKHHVFLVRNWEKIRQKQEEVKHTSDNIHSASLYTRWNGICRDDGNIKSDVFMTQFSAL
QTARSVRTRRLAAAEENIEVARAARLAQIFKEICDGIISYKDSSRQALAAPLLNLPPKKKNADYYEKISDPLDLITIEKQILTGYYKTVE
AFDADMLKVFRNAEKYYGRKSPVGRDVCRLRKAYYNARHEASAQIDEIVGETASEADSSETSVSEKENGHEKDDDVIRCICGLYKDEGLM
IQCDKCMVWQHCDCMGVNSDVEHYLCEQCDPRPVDREVPMIPRPHYAQPGCVYFICLLRDDLLLRQGDCVYLMRDSRRTPDGHPVRQSYR
LLSHINRDKLDIFRIEKLWKNEKEERFAFGHHYFRPHETHHSPSRRFYHNELFRVPLYEIIPLEAVVGTCCVLDLYTYCKGRPKGVKEQD
VYICDYRLDKSAHLFYKIHRNRYPVCTKPYAFDHFPKKLTPKKDFSPHYVPDNYKRNGGRSSWKSERSKPPLKDLGQEDDALPLIEEVLA
SQEQAANEIPSLEEPEREGATANVSEGEKKTEESSQEPQSTCTPEERRHNQRERLNQILLNLLEKIPGKNAIDVTYLLEEGSGRKLRRRT

--------------------------------------------------------------
>59665_59665_4_NOS1AP-ASH1L_NOS1AP_chr1_162257226_ENST00000530878_ASH1L_chr1_155452240_ENST00000392403_length(transcript)=10754nt_BP=674nt
ACCGTCGCCTTTTCTTCTTCGTCCCGGGCGGTGCGTTCCACTGCTCTGGGGCCGGCGCCGCGCCCAGTCCCGCTTCGGGCCGCAAGCCCC
ACCGCTCCCCTCCCCGGGCAGGGGCGCCGCGCAGCCCGCTCCCGCCGCCACCTCCTCCCCTGCCGCCCTCCTAGCCGGCAGGAATTGCGC
GACCACAGCGCCGCTCGCGTCGCCCGCATCAGCTCAGCCCGCTGCCGCTCGGCCCTCGGCACCGCTCCGGGTCCGGCCGCCGCGCGGCCA
GGGCTCCCCCTGCCCAGCGCTCCCAGGCCCCGCCACGCGTCGCCGCGCCCAGCTCCAGTCTCCCCTCCCCGGGGTCTCGCCAGCCCCTTC
CTGCAGCCGCCGCCTCCGAAGGAGCGGGTCCGCCGCGGGTAACCATGCCTAGCAAAACCAAGTACAACCTTGTGGACGATGGGCACGACC
TGCGGATCCCCTTGCACAACGAGGACGCCTTCCAGCACGGCATCTGCTTTGAGGCCAAGTACGTAGGAAGCCTGGACGTGCCAAGGCCCA
ACAGCAGGGTGGAGATCGTGGCTGCCATGCGCCGGATACGGTATGAGTTTAAAGCCAAGAACATCAAGAAGAAGAAAGTGAGCATTATGG
TTTCAGTGGATGGAGTGAAAGTGATTCTGAAGAAGAAGAAAAAGGACCCTTCAAAGTTGTACAAGAAAGCAGATGATGTTGCAGCCATTG
AATGCCAGTCTGAAGAAGTCATCCGTCTTCATTCACAGGGAGAAAACAATCCTTTGTCTAAGAAGCTGTCTCCAGTACACTCAGAAATGG
CAGATTATATTAATGCAACGCCATCTACTCTTCTTGGTAGCCGGGATCCTGATTTAAAGGACAGAGCATTACTTAATGGAGGAACTAGTG
TAACAGAAAAGTTGGCACAGCTGATTGCTACCTGTCCTCCTTCCAAGTCTTCCAAGACAAAACCGAAGAAGTTAGGAACTGGCACTACAG
CAGGATTGGTTAGCAAGGATTTGATCAGGAAAGCAGGTGTTGGCTCTGTAGCTGGAATAATACATAAGGACTTAATAAAAAAGCCAACCA
TCAGCACAGCAGTTGGATTGGTAACTAAAGATCCTGGGAAAAAGCCAGTGTTTAATGCAGCAGTAGGATTGGTCAATAAGGACTCTGTGA
AAAAACTGGGAACTGGCACTACAGCGGTATTCATTAATAAAAACTTAGGCAAAAAGCCAGGAACTATCACTACAGTAGGACTGCTAAGCA
AAGATTCAGGAAAGAAGCTAGGAATTGGTATTGTTCCAGGTTTAGTGCATAAAGAGTCTGGCAAGAAGTTAGGACTTGGCACTGTGGTTG
GACTGGTTAATAAAGATTTGGGAAAGAAATTGGGTTCTACTGTTGGCCTAGTGGCCAAGGACTGTGCAAAGAAGATTGTAGCAAGTTCAG
CAATGGGATTGGTTAATAAGGACATTGGAAAGAAACTAATGAGTTGTCCTTTGGCAGGTCTGATCAGTAAAGATGCCATAAACCTTAAAG
CCGAAGCACTGCTCCCCACTCAGGAACCGCTTAAGGCTTCTTGTAGTACAAACATCAATAATCAGGAAAGTCAGGAACTTTCTGAATCCC
TGAAAGATAGTGCCACCAGCAAAACTTTTGAAAAGAATGTTGTACGGCAGAATAAAGAAAGCATATTGGAAAAGTTCTCAGTACGAAAAG
AAATCATTAATTTGGAGAAAGAAATGTTTAATGAAGGAACATGCATTCAGCAAGACAGTTTCTCATCCAGTGAAAAGGGATCTTATGAAA
CCTCAAAGCATGAAAAGCAGCCTCCTGTATATTGCACTTCTCCGGACTTTAAAATGGGAGGTGCTTCTGATGTATCTACCGCTAAATCCC
CATTCAGTGCAGTAGGAGAAAGCAATCTCCCTTCCCCATCACCTACTGTATCTGTTAATCCTTTAACCAGAAGTCCCCCTGAAACTTCTT
CACAGTTGGCTCCTAATCCATTACTTTTAAGTTCTACTACAGAACTAATCGAAGAAATTTCTGAATCTGTTGGAAAGAACCAGTTTACTT
CTGAAAGTACCCACTTGAACGTTGGTCATAGGTCAGTTGGTCATAGTATAAGTATTGAATGTAAAGGGATTGATAAAGAGGTAAATGATT
CAAAAACTACCCATATAGATATTCCAAGAATAAGCTCTTCCCTTGGAAAAAAGCCAAGTTTGACTTCTGAATCCAGCATTCATACTATTA
CTCCTTCAGTTGTTAACTTCACTAGTTTATTTAGTAATAAGCCTTTTTTAAAACTGGGTGCAGTATCTGCATCAGACAAACACTGCCAAG
TTGCTGAAAGCCTAAGTACTAGTTTGCAGTCCAAACCATTAAAAAAAAGAAAAGGAAGAAAACCTCGGTGGACTAAAGTGGTGGCAAGAA
GCACATGCCGGTCTCCAAAAGGGCTAGAATTAGAAAGATCAGAGCTTTTTAAAAACGTTTCATGTAGCTCACTATCAAATAGTAATTCTG
AGCCAGCCAAGTTTATGAAAAACATTGGACCCCCTTCATTTGTAGATCATGACTTCCTTAAACGCCGATTGCCAAAGTTGAGCAAATCCA
CAGCTCCATCTCTTGCTCTCTTAGCTGATAGTGAAAAACCATCTCATAAGTCTTTTGCTACTCACAAACTATCCTCCAGTATGTGTGTCT
CTAGTGACCTTTTGTCTGATATTTATAAGCCCAAAAGAGGAAGGCCTAAATCTAAGGAGATGCCTCAACTGGAAGGGCCACCTAAAAGGA
CTTTAAAAATCCCTGCTTCTAAAGTGTTTTCTTTACAGTCTAAGGAAGAACAAGAACCCCCAATTTTACAGCCAGAAATTGAAATCCCTT
CCTTCAAACAAGGTCTGTCTGTGTCTCCTTTTCCAAAAAAGAGAGGCAGGCCTAAGAGGCAAATGAGGTCACCAGTCAAGATGAAGCCAC
CTGTACTGTCAGTGGCTCCATTTGTTGCCACTGAAAGTCCAAGCAAGCTAGAATCTGAAAGTGACAACCATAGAAGTAGCAGTGATTTCT
TTGAGAGCGAGGATCAACTTCAGGATCCAGATGACCTAGATGACAGTCATAGGCCAAGTGTCTGTAGTATGAGTGACCTTGAGATGGAAC
CAGATAAAAAAATTACCAAGAGAAACAATGGACAATTAATGAAAACAATTATCCGCAAAATAAATAAAATGAAGACTTTAAAGAGAAAGA
AACTGTTGAATCAGATTCTTTCAAGTTCTGTAGAATCAAGTAATAAAGGGAAAGTGCAATCCAAACTCCATAATACGGTATCAAGTCTTG
CTGCCACATTTGGCTCTAAATTGGGCCAACAGATAAATGTCAGCAAGAAAGGAACCATTTATATAGGAAAGAGAAGAGGTCGCAAACCAA
AAACTGTCTTAAATGGTATTCTTTCTGGTAGTCCTACTAGCCTTGCTGTTCTTGAGCAAACAGCTCAACAGGCAGCTGGGTCAGCATTAG
GACAGATTCTTCCCCCATTACTGCCTTCATCTGCTAGTAGTTCTGAGATTCTTCCATCACCTATTTGCTCTCAGTCTTCTGGGACTAGTG
GAGGTCAGAGCCCTGTAAGTAGTGATGCAGGTTTTGTTGAACCCAGTTCAGTGCCATATTTGCATTTACACTCCAGACAGGGCAGTATGA
TTCAGACTCTTGCAATGAAGAAGGCCTCAAAGGGGAGGAGGCGGTTATCTCCTCCTACTTTGTTGCCAAATTCTCCTTCGCACTTGAGTG
AACTCACATCTCTAAAAGAAGCTACTCCTTCCCCAATCAGTGAGTCTCATAGTGATGAGACCATTCCCAGTGATAGTGGAATTGGAACAG
ATAATAACAGCACATCAGACAGGGCAGAGAAATTTTGTGGGCAAAAAAAGAGGAGGCATTCTTTTGAGCATGTTTCTCTGATTCCCCCTG
AAACCTCTACAGTGCTAAGCAGTCTTAAAGAAAAACATAAACACAAATGTAAGCGCAGGAATCATGATTACCTCAGCTATGACAAGATGA
AAAGGCAGAAACGAAAACGGAAAAAGAAATATCCCCAGCTTCGAAATAGACAGGATCCAGACTTTATTGCAGAGCTGGAGGAACTAATAA
GTCGCCTAAGTGAAATTCGGATCACTCATCGAAGTCATCATTTTATCCCCCGAGATCTTCTGCCAACTATCTTTCGAATCAACTTTAATA
GTTTCTATACACATCCTTCTTTCCCCTTAGACCCTTTGCACTACATTCGAAAACCTGACTTAAAAAAGAAAAGAGGGAGACCCCCTAAGA
TGAGGGAGGCAATGGCTGAAATGCCTTTTATGCACAGCCTTAGTTTTCCTCTTTCTAGTACTGGATTCTATCCATCTTATGGTATGCCTT
ACTCTCCTTCACCCCTTACAGCTGCTCCCATAGGATTAGGTTACTATGGAAGGTATCCTCCCACTCTTTATCCACCTCCTCCATCTCCTT
CTTTCACCACGCCACTTCCACCTCCTTCCTATATGCATGCTGGTCATTTACTTCTCAATCCTGCCAAATACCATAAGAAAAAGCATAAGC
TACTTCGACAGGAGGCCTTTCTTACAACCAGCAGGACTCCCCTCCTTTCCATGAGTACCTACCCCAGTGTTCCTCCTGAGATGGCCTATG
GTTGGATGGTTGAGCACAAACACAGGCACCGTCACAAACACAGAGAACACCGTTCTTCTGAACAACCCCAGGTTTCTATGGACACTGGCT
CTTCCCGATCTGTCCTGGAATCTTTGAAGCGCTATAGATTTGGAAAGGATGCTGTTGGAGAGCGATATAAGCATAAGGAAAAGCACCGTT
GTCACATGTCCTGCCCTCATCTCTCTCCTTCAAAAAGCTTAATAAACAGAGAGGAACAGTGGGTCCACCGAGAGCCTTCAGAATCTAGTC
CATTGGCCTTGGGATTGCAGACACCTTTACAGATTGACTGTTCAGAAAGTTCTCCAAGCTTATCCCTTGGAGGATTCACTCCCAACTCTG
AGCCAGCCAGCAGTGATGAACATACAAACCTTTTCACAAGTGCAATAGGCAGCTGCAGAGTTTCAAACCCTAACTCCAGTGGCCGGAAGA
AATTAACTGACAGCCCTGGACTCTTTTCTGCACAGGACACTTCACTAAATCGGCTTCACAGAAAGGAGTCACTGCCTTCTAACGAAAGGG
CAGTACAGACTTTGGCAGGCTCCCAGCCAACCTCTGATAAACCCTCCCAGCGGCCATCAGAGAGCACAAATTGTAGCCCTACCCGGAAAA
GGTCTTCATCTGAGAGTACTTCTTCAACAGTAAACGGAGTTCCCTCTCGAAGTCCAAGATTAGTTGCTTCTGGGGATGACTCTGTGGATA
GTCTGCTGCAGCGGATGGTACAAAATGAGGACCAAGAGCCCATGGAGAAAAGTATTGATGCTGTGATTGCAACTGCCTCTGCACCACCTT
CTTCCAGTCCAGGCCGTAGCCACAGCAAGGACCGAACCCTGGGAAAACCAGACAGCCTTTTAGTGCCTGCAGTCACAAGTGACTCTTGCA
ATAATAGCATCTCACTCCTATCTGAAAAGTTGACAAGCAGCTGTTCCCCCCATCATATCAAGAGAAGTGTAGTGGAAGCTATGCAACGCC
AAGCTCGGAAAATGTGCAATTACGACAAAATCTTGGCCACAAAGAAAAACCTAGACCATGTCAATAAAATCTTAAAAGCCAAAAAACTTC
AAAGGCAGGCCAGGACAGGGAATAACTTTGTGAAACGTAGGCCAGGTCGACCTCGGAAATGTCCCCTTCAGGCTGTCGTATCAATGCAAG
CATTCCAGGCTGCTCAGTTTGTCAACCCAGAATTGAACAGAGACGAGGAAGGAGCAGCACTGCACCTCAGTCCTGACACAGTTACAGATG
TAATTGAGGCTGTTGTTCAGAGTGTAAATCTGAACCCAGAACATAAAAAGGGGTTGAAGAGAAAAGGTTGGCTATTGGAAGAACAGACCA
GAAAAAAGCAGAAGCCATTACCAGAGGAAGAAGAGCAAGAGAATAATAAAAGCTTTAATGAAGCACCAGTTGAGATTCCCAGTCCTTCTG
AAACCCCAGCTAAACCTTCTGAACCTGAAAGTACCTTGCAGCCTGTGCTTTCTCTCATCCCAAGGGAAAAGAAGCCCCCACGTCCCCCAA
AGAAGAAGTATCAGAAAGCAGGGCTGTATTCTGACGTTTACAAAACTACAGACCCAAAGAGTCGATTGATCCAATTAAAGAAAGAGAAGC
TGGAGTATACTCCAGGAGAGCATGAATATGGATTATTTCCAGCGCCCATTCATGTTGGAAAGTATCTAAGACAAAAGAGAATTGACTTCC
AGCTTCCTTATGATATCCTTTGGCAGTGGAAACACAATCAGCTATACAAAAAGCCAGATGTCCCACTATATAAGAAAATTCGTTCAAATG
TCTACGTTGATGTCAAACCCCTTTCTGGTTACGAAGCTACCACCTGTAACTGTAAGAAGCCAGATGATGACACCAGGAAGGGCTGTGTTG
ATGACTGCCTCAATAGAATGATCTTTGCTGAGTGTTCCCCCAACACTTGCCCATGTGGCGAGCAATGCTGTAACCAGAGGATACAGAGGC
ATGAATGGGTGCAATGTCTAGAACGATTTCGAGCTGAGGAAAAAGGTTGGGGAATCAGAACCAAAGAGCCCCTAAAAGCTGGGCAGTTCA
TCATTGAATACCTAGGGGAGGTCGTCAGTGAACAGGAGTTCAGGAACAGGATGATTGAGCAGTATCATAATCACAGTGACCACTACTGCC
TGAACCTGGATAGTGGGATGGTGATTGACAGTTACCGCATGGGAAATGAGGCCCGATTCATCAACCATAGCTGTGACCCAAATTGTGAAA
TGCAGAAATGGTCTGTTAATGGAGTATACCGGATTGGACTCTATGCTCTTAAAGACATGCCAGCTGGGACTGAACTCACTTATGATTATA
ACTTTCATTCCTTCAATGTGGAAAAACAGCAACTTTGTAAGTGTGGCTTTGAGAAATGTCGAGGAATCATCGGAGGCAAGAGTCAGCGTG
TGAATGGACTCACCAGCAGCAAAAACAGCCAGCCCATGGCCACACACAAAAAATCTGGACGGTCAAAAGAGAAGAGAAAGTCTAAGCACA
AGCTGAAGAAAAGGAGAGGCCATCTCTCTGAGGAACCCAGTGAAAATATCAACACCCCAACTAGATTGACCCCCCAATTACAGATGAAGC
CAATGTCCAATCGTGAAAGGAACTTTGTGTTAAAGCATCATGTATTCTTGGTCCGAAACTGGGAGAAGATTCGTCAAAAACAGGAGGAAG
TAAAGCACACCAGTGATAATATTCACTCAGCATCATTATATACCCGTTGGAATGGGATCTGCCGAGATGATGGGAATATCAAGTCTGATG
TCTTCATGACCCAGTTCTCTGCCCTGCAGACAGCTCGATCTGTTCGAACAAGACGGTTGGCAGCTGCAGAGGAAAATATTGAAGTGGCTC
GGGCAGCCCGCCTAGCCCAGATCTTCAAAGAAATTTGTGATGGTATCATCTCTTATAAAGATTCTTCCCGGCAAGCACTGGCAGCTCCAC
TTTTGAACCTTCCCCCAAAGAAAAAGAATGCTGATTATTATGAGAAGATCTCTGATCCCCTAGATCTTATCACCATAGAGAAGCAGATCC
TCACTGGTTACTATAAGACAGTGGAAGCTTTTGATGCTGACATGCTCAAAGTCTTTCGGAATGCTGAGAAGTACTATGGGCGTAAATCCC
CAGTTGGGAGAGATGTTTGTCGTCTACGAAAGGCCTATTACAATGCCCGGCATGAGGCATCAGCCCAGATTGATGAGATTGTGGGAGAGA
CAGCAAGTGAGGCAGACAGCAGTGAGACCTCAGTCTCTGAAAAGGAGAATGGGCATGAGAAGGACGACGATGTTATTCGCTGTATCTGTG
GCCTCTACAAGGATGAAGGTCTCATGATCCAGTGTGACAAGTGCATGGTATGGCAGCACTGTGATTGTATGGGAGTGAACTCAGATGTGG
AGCACTACCTTTGTGAGCAGTGTGACCCAAGGCCTGTGGACAGGGAGGTTCCCATGATCCCTCGGCCCCACTATGCCCAACCTGGCTGTG
TCTACTTCATCTGTTTGCTCCGAGATGACTTGCTGCTTCGTCAGGGTGACTGTGTGTATCTGATGAGGGATAGTCGGCGCACCCCTGATG
GCCACCCGGTCCGTCAGTCCTATCGACTGTTATCTCACATTAACCGAGATAAACTTGACATCTTTCGCATTGAGAAGCTTTGGAAGAATG
AAAAAGAGGAACGGTTTGCCTTTGGTCACCATTATTTCCGTCCCCACGAAACACACCACTCTCCATCCCGTCGGTTCTATCATAATGAAC
TATTTCGGGTGCCACTCTATGAGATCATTCCCTTGGAGGCTGTAGTGGGGACCTGCTGTGTGTTGGACCTTTATACGTATTGTAAAGGGA
GACCCAAAGGAGTAAAGGAGCAAGATGTGTACATCTGTGATTATCGGCTTGACAAGTCAGCACACCTGTTTTACAAGATCCACCGGAACC
GCTATCCTGTCTGCACCAAACCCTATGCTTTTGATCACTTCCCCAAGAAGCTCACTCCCAAAAAAGATTTCTCGCCTCATTACGTCCCAG
ACAACTACAAGAGGAATGGAGGACGATCATCCTGGAAGTCTGAGCGCTCAAAGCCACCCCTAAAAGACTTGGGCCAGGAGGATGATGCTC
TACCCTTGATTGAAGAGGTTCTAGCCAGTCAAGAGCAAGCAGCCAATGAGATACCCAGCCTGGAGGAGCCAGAACGGGAAGGGGCCACTG
CTAACGTCAGTGAGGGTGAAAAAAAAACAGAGGAAAGTAGTCAAGAACCCCAGTCAACCTGTACCCCTGAGGAACGACGGCATAACCAAC
GGGAACGACTCAACCAGATCTTGCTCAATCTCCTTGAAAAAATCCCTGGAAAAAATGCCATTGATGTGACCTACTTGCTGGAGGAAGGAT
CAGGCAGGAAACTGCGAAGGCGTACTTTGTTTATCCCAGAAAACAGCTTTCGAAAGTGACCCTCAAAGAATGAGAACCTCAAGCATCTGG
GATCCAGTGGAGCTAATCAGTCCTGCCTCCTGCTCTCTGGGTATAGACAGGGGTGGGAAGGGTCCATCTGGGCAAGGGGAATGGGGCCAT
GTTGTTGACATTAGGTACTTAATAAGCCTTGGAGCTAGTGGAGAGGGAGAGGAAAGGGTTCTGTCCAAGACAGTTCAGGTTAATTAATTT
TCTTCTCCATTGCTTCACCTTAAGGGTTAATAATGTAGAGAGGAGGGAGGACCACATTGATGACCAGAACCTACTGGTACTTTATAGCAT
TTGCCCCACCCCACAGCTTAGGTTTTTCTGTCATCCTCAGATCCCACAGGCATTGCGAAGAAGCTGCTTCCTATACCCAGGTATAACTCA
AAATCCAAAGGGATAGGGCCAGGATCCCTATTCCTACCCCATCTATTCTCTGTTGGCTCCAAGAGCTACCCCAGAGACCTTAAACAGAAA
CAGTAGCTGAGGCTTCTTCCTAGATACCTGACTAGGGAAGTTTGTCTCTCCTTTCTTGCCCAACCAGGTCAAAGTAAAATGTGAGTTGAC
AGCTCAAAGCACTTGTAACTGCTGCCCCCTCCCTACCTCTACTCCCCAAAATGGAATCATGGGATAGGGAAGGCCCCCATGGGGTCAGAA
GGGCACGGTAGTTCTTGCAATTATTTTTGTTTTACCCTTCATAACCTGTCAAACATATTTTTTTCTAATGAGAAAGCCAGGCCCCCGCCA
GCACACATGCTGTTTTTAATGCGCTGTAGTTCTTGTGTGTCTGCTGTGCTGTGCAAATGGAGATTCAGTTCAAAATAAAATCATTTAAAA
ACCTACATAAAAAGAACTCTAAACCCACCCCTGCAACAAAAGTCACTACATAAACTGTTCAGCAGTATTCACCTATCAGAGTATTTGTTG
TGAGTATAGATTATCAATTGAAAACACTACTCTTGTTTTCTTAATTGTACAGTTTTCAATGTCCCTTTCTTAAAGAGACAGTATATTTCT
CTTCACCCCTAGCCCATCTTCCCTCACCCTCCTGAATGACATCAGGAGGTATATCCAGGGTGTCTCCTTCCTTCCTACTCTCTTGACCAG
AAGTTAACAGACTATACTGTCTCTTTAAAAATAAAATTTAAAAAGCTTTGTTGTCTTTTCAGACATACATATGCATATATGTTTTAGATG
TTCTTATAAGAGAAAAGATGGTTTTTAAATGTGCCAAGTTGTGTGTGTGTGTGTATATATATGTGTGTATGTGTGTGTATATATATATGT
GTGTGTGTATATATATACACACACACACACACACCTGCTGTGTGATTGGTAAGCAATACAATAGTAAACATGTCCCCATTACTTTTTTCT
AATATTGGACCAATGCTGTCCTAATTGTACATTTCCCCTTATGGTGACGATGCTCTGACTCGTTTAGGTAGACACATTGACCACCTTCCA
TTCCATTAAATATTTTTTCCTTTTTCCCCTTTCTGTGTCATTCTTGAGGAAAAAACAAAAGAGAGAGGGGATGCCAATGATCCCCTTGAG

>59665_59665_4_NOS1AP-ASH1L_NOS1AP_chr1_162257226_ENST00000530878_ASH1L_chr1_155452240_ENST00000392403_length(amino acids)=2975AA_BP=151
MPLGPRHRSGSGRRAARAPPAQRSQAPPRVAAPSSSLPSPGSRQPLPAAAASEGAGPPRVTMPSKTKYNLVDDGHDLRIPLHNEDAFQHG
ICFEAKYVGSLDVPRPNSRVEIVAAMRRIRYEFKAKNIKKKKVSIMVSVDGVKVILKKKKKDPSKLYKKADDVAAIECQSEEVIRLHSQG
ENNPLSKKLSPVHSEMADYINATPSTLLGSRDPDLKDRALLNGGTSVTEKLAQLIATCPPSKSSKTKPKKLGTGTTAGLVSKDLIRKAGV
GSVAGIIHKDLIKKPTISTAVGLVTKDPGKKPVFNAAVGLVNKDSVKKLGTGTTAVFINKNLGKKPGTITTVGLLSKDSGKKLGIGIVPG
LVHKESGKKLGLGTVVGLVNKDLGKKLGSTVGLVAKDCAKKIVASSAMGLVNKDIGKKLMSCPLAGLISKDAINLKAEALLPTQEPLKAS
CSTNINNQESQELSESLKDSATSKTFEKNVVRQNKESILEKFSVRKEIINLEKEMFNEGTCIQQDSFSSSEKGSYETSKHEKQPPVYCTS
PDFKMGGASDVSTAKSPFSAVGESNLPSPSPTVSVNPLTRSPPETSSQLAPNPLLLSSTTELIEEISESVGKNQFTSESTHLNVGHRSVG
HSISIECKGIDKEVNDSKTTHIDIPRISSSLGKKPSLTSESSIHTITPSVVNFTSLFSNKPFLKLGAVSASDKHCQVAESLSTSLQSKPL
KKRKGRKPRWTKVVARSTCRSPKGLELERSELFKNVSCSSLSNSNSEPAKFMKNIGPPSFVDHDFLKRRLPKLSKSTAPSLALLADSEKP
SHKSFATHKLSSSMCVSSDLLSDIYKPKRGRPKSKEMPQLEGPPKRTLKIPASKVFSLQSKEEQEPPILQPEIEIPSFKQGLSVSPFPKK
RGRPKRQMRSPVKMKPPVLSVAPFVATESPSKLESESDNHRSSSDFFESEDQLQDPDDLDDSHRPSVCSMSDLEMEPDKKITKRNNGQLM
KTIIRKINKMKTLKRKKLLNQILSSSVESSNKGKVQSKLHNTVSSLAATFGSKLGQQINVSKKGTIYIGKRRGRKPKTVLNGILSGSPTS
LAVLEQTAQQAAGSALGQILPPLLPSSASSSEILPSPICSQSSGTSGGQSPVSSDAGFVEPSSVPYLHLHSRQGSMIQTLAMKKASKGRR
RLSPPTLLPNSPSHLSELTSLKEATPSPISESHSDETIPSDSGIGTDNNSTSDRAEKFCGQKKRRHSFEHVSLIPPETSTVLSSLKEKHK
HKCKRRNHDYLSYDKMKRQKRKRKKKYPQLRNRQDPDFIAELEELISRLSEIRITHRSHHFIPRDLLPTIFRINFNSFYTHPSFPLDPLH
YIRKPDLKKKRGRPPKMREAMAEMPFMHSLSFPLSSTGFYPSYGMPYSPSPLTAAPIGLGYYGRYPPTLYPPPPSPSFTTPLPPPSYMHA
GHLLLNPAKYHKKKHKLLRQEAFLTTSRTPLLSMSTYPSVPPEMAYGWMVEHKHRHRHKHREHRSSEQPQVSMDTGSSRSVLESLKRYRF
GKDAVGERYKHKEKHRCHMSCPHLSPSKSLINREEQWVHREPSESSPLALGLQTPLQIDCSESSPSLSLGGFTPNSEPASSDEHTNLFTS
AIGSCRVSNPNSSGRKKLTDSPGLFSAQDTSLNRLHRKESLPSNERAVQTLAGSQPTSDKPSQRPSESTNCSPTRKRSSSESTSSTVNGV
PSRSPRLVASGDDSVDSLLQRMVQNEDQEPMEKSIDAVIATASAPPSSSPGRSHSKDRTLGKPDSLLVPAVTSDSCNNSISLLSEKLTSS
CSPHHIKRSVVEAMQRQARKMCNYDKILATKKNLDHVNKILKAKKLQRQARTGNNFVKRRPGRPRKCPLQAVVSMQAFQAAQFVNPELNR
DEEGAALHLSPDTVTDVIEAVVQSVNLNPEHKKGLKRKGWLLEEQTRKKQKPLPEEEEQENNKSFNEAPVEIPSPSETPAKPSEPESTLQ
PVLSLIPREKKPPRPPKKKYQKAGLYSDVYKTTDPKSRLIQLKKEKLEYTPGEHEYGLFPAPIHVGKYLRQKRIDFQLPYDILWQWKHNQ
LYKKPDVPLYKKIRSNVYVDVKPLSGYEATTCNCKKPDDDTRKGCVDDCLNRMIFAECSPNTCPCGEQCCNQRIQRHEWVQCLERFRAEE
KGWGIRTKEPLKAGQFIIEYLGEVVSEQEFRNRMIEQYHNHSDHYCLNLDSGMVIDSYRMGNEARFINHSCDPNCEMQKWSVNGVYRIGL
YALKDMPAGTELTYDYNFHSFNVEKQQLCKCGFEKCRGIIGGKSQRVNGLTSSKNSQPMATHKKSGRSKEKRKSKHKLKKRRGHLSEEPS
ENINTPTRLTPQLQMKPMSNRERNFVLKHHVFLVRNWEKIRQKQEEVKHTSDNIHSASLYTRWNGICRDDGNIKSDVFMTQFSALQTARS
VRTRRLAAAEENIEVARAARLAQIFKEICDGIISYKDSSRQALAAPLLNLPPKKKNADYYEKISDPLDLITIEKQILTGYYKTVEAFDAD
MLKVFRNAEKYYGRKSPVGRDVCRLRKAYYNARHEASAQIDEIVGETASEADSSETSVSEKENGHEKDDDVIRCICGLYKDEGLMIQCDK
CMVWQHCDCMGVNSDVEHYLCEQCDPRPVDREVPMIPRPHYAQPGCVYFICLLRDDLLLRQGDCVYLMRDSRRTPDGHPVRQSYRLLSHI
NRDKLDIFRIEKLWKNEKEERFAFGHHYFRPHETHHSPSRRFYHNELFRVPLYEIIPLEAVVGTCCVLDLYTYCKGRPKGVKEQDVYICD
YRLDKSAHLFYKIHRNRYPVCTKPYAFDHFPKKLTPKKDFSPHYVPDNYKRNGGRSSWKSERSKPPLKDLGQEDDALPLIEEVLASQEQA
ANEIPSLEEPEREGATANVSEGEKKTEESSQEPQSTCTPEERRHNQRERLNQILLNLLEKIPGKNAIDVTYLLEEGSGRKLRRRTLFIPE

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Fusion Gene PPI Analysis for NOS1AP-ASH1L


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneNOS1APchr1:162257226chr1:155452240ENST00000361897+310494_50690.0507.0NOS1
HgeneNOS1APchr1:162257226chr1:155452240ENST00000493151+12494_5060212.0NOS1
HgeneNOS1APchr1:162257226chr1:155452240ENST00000530878+310494_50690.0502.0NOS1


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for NOS1AP-ASH1L


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for NOS1AP-ASH1L


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneNOS1APC0035828Romano-Ward Syndrome2ORPHANET
HgeneNOS1APC0036341Schizophrenia2PSYGENET
TgeneC4540478MENTAL RETARDATION, AUTOSOMAL DOMINANT 524GENOMICS_ENGLAND;UNIPROT
TgeneC3714756Intellectual Disability2GENOMICS_ENGLAND
TgeneC0023903Liver neoplasms1CTD_human
TgeneC0033578Prostatic Neoplasms1CTD_human
TgeneC0345904Malignant neoplasm of liver1CTD_human
TgeneC0376358Malignant neoplasm of prostate1CTD_human
TgeneC1535926Neurodevelopmental Disorders1CTD_human