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in Kim Lab

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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:CTIF-C5orf56 (FusionGDB2 ID:HG9811TG441108)

Fusion Gene Summary for CTIF-C5orf56

check button Fusion gene summary
Fusion gene informationFusion gene name: CTIF-C5orf56
Fusion gene ID: hg9811tg441108
HgeneTgene
Gene symbol

CTIF

C5orf56

Gene ID

9811

441108

Gene namecap binding complex dependent translation initiation factorIRF1 antisense RNA 1
SynonymsGm672|KIAA0427C5orf56
Cytomap('CTIF')('C5orf56')

18q21.1

5q31.1

Type of geneprotein-codingncRNA
DescriptionCBP80/20-dependent translation initiation factoruncharacterized protein C5orf56
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000256413, ENST00000382998, 
ENST00000592658, 		ENST00000592658, 
ENST00000256413, ENST00000382998, 
Fusion gene scores* DoF score20 X 11 X 10=22005 X 4 X 5=100
# samples 235
** MAII scorelog2(23/2200*10)=-3.25779775746765
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(5/100*10)=-1
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: CTIF [Title/Abstract] AND C5orf56 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCTIF(46288060)-C5orf56(131785342), # samples:3
Anticipated loss of major functional domain due to fusion event.CTIF-C5orf56 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
CTIF-C5orf56 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
CTIF-C5orf56 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
CTIF-C5orf56 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
C5orf56-CTIF seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
C5orf56-CTIF seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across CTIF (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across C5orf56 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4UCECTCGA-DF-A2KR-01ACTIFchr18

46288060

-C5orf56chr5

131785342

+
ChimerDB4UCECTCGA-DF-A2KR-01ACTIFchr18

46288060

+C5orf56chr5

131785342

+


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Fusion Gene ORF analysis for CTIF-C5orf56

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000256413ENST00000464024CTIFchr18

46288060

+C5orf56chr5

131785342

+
5CDS-intronENST00000382998ENST00000464024CTIFchr18

46288060

+C5orf56chr5

131785342

+
In-frameENST00000256413ENST00000337752CTIFchr18

46288060

+C5orf56chr5

131785342

+
In-frameENST00000256413ENST00000378947CTIFchr18

46288060

+C5orf56chr5

131785342

+
In-frameENST00000256413ENST00000378953CTIFchr18

46288060

+C5orf56chr5

131785342

+
In-frameENST00000256413ENST00000407797CTIFchr18

46288060

+C5orf56chr5

131785342

+
In-frameENST00000382998ENST00000337752CTIFchr18

46288060

+C5orf56chr5

131785342

+
In-frameENST00000382998ENST00000378947CTIFchr18

46288060

+C5orf56chr5

131785342

+
In-frameENST00000382998ENST00000378953CTIFchr18

46288060

+C5orf56chr5

131785342

+
In-frameENST00000382998ENST00000407797CTIFchr18

46288060

+C5orf56chr5

131785342

+
intron-3CDSENST00000592658ENST00000337752CTIFchr18

46288060

+C5orf56chr5

131785342

+
intron-3CDSENST00000592658ENST00000378947CTIFchr18

46288060

+C5orf56chr5

131785342

+
intron-3CDSENST00000592658ENST00000378953CTIFchr18

46288060

+C5orf56chr5

131785342

+
intron-3CDSENST00000592658ENST00000407797CTIFchr18

46288060

+C5orf56chr5

131785342

+
intron-intronENST00000592658ENST00000464024CTIFchr18

46288060

+C5orf56chr5

131785342

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000256413CTIFchr1846288060+ENST00000378953C5orf56chr5131785342+208416662951971558
ENST00000256413CTIFchr1846288060+ENST00000337752C5orf56chr5131785342+351216662951998567
ENST00000256413CTIFchr1846288060+ENST00000378947C5orf56chr5131785342+211616662951860521
ENST00000256413CTIFchr1846288060+ENST00000407797C5orf56chr5131785342+257516662951731478
ENST00000382998CTIFchr1846288060+ENST00000378953C5orf56chr5131785342+205216342571939560
ENST00000382998CTIFchr1846288060+ENST00000337752C5orf56chr5131785342+348016342571966569
ENST00000382998CTIFchr1846288060+ENST00000378947C5orf56chr5131785342+208416342571828523
ENST00000382998CTIFchr1846288060+ENST00000407797C5orf56chr5131785342+254316342571699480

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000256413ENST00000378953CTIFchr1846288060+C5orf56chr5131785342+0.0288321470.97116786
ENST00000256413ENST00000337752CTIFchr1846288060+C5orf56chr5131785342+0.0090950660.990905
ENST00000256413ENST00000378947CTIFchr1846288060+C5orf56chr5131785342+0.0426820670.957318
ENST00000256413ENST00000407797CTIFchr1846288060+C5orf56chr5131785342+0.0223500060.9776499
ENST00000382998ENST00000378953CTIFchr1846288060+C5orf56chr5131785342+0.0375195970.9624804
ENST00000382998ENST00000337752CTIFchr1846288060+C5orf56chr5131785342+0.0115243530.9884757
ENST00000382998ENST00000378947CTIFchr1846288060+C5orf56chr5131785342+0.0539017470.9460983
ENST00000382998ENST00000407797CTIFchr1846288060+C5orf56chr5131785342+0.0280439820.97195596

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Fusion Genomic Features for CTIF-C5orf56


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
CTIFchr1846288060+C5orf56chr5131785341+0.0001304880.99986947
CTIFchr1846288060+C5orf56chr5131785341+0.0001304880.99986947

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for CTIF-C5orf56


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr18:46288060/chr5:131785342)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCTIFchr18:46288060chr5:131785342ENST00000256413+912376_577457599.0DomainNote=MIF4G
HgeneCTIFchr18:46288060chr5:131785342ENST00000382998+1013376_577459601.0DomainNote=MIF4G


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Fusion Gene Sequence for CTIF-C5orf56


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>20229_20229_1_CTIF-C5orf56_CTIF_chr18_46288060_ENST00000256413_C5orf56_chr5_131785342_ENST00000337752_length(transcript)=3512nt_BP=1666nt
CTTTCCCTGTGTCAGATCAGGGATCATTTTTTTTCCTTCCTCTACTCCCTCCCCCCTACCCGCCCCTCCCTCCCTGTTTCCCTTCCCTCC
CTCCCTCCCCTCTCTGCTGGGTCTGTGCGCTGGGGCGCCCGATCCCCTCCGCAGCTGGGACGCTCCGAACTCGAGGCAGGAGTCGGCTCT
CCGGAGCCTCGTCCCTCCCTTCCCCTTCCCTGCCCCCTTCCCCCACCCCCGACTCGGGCTTGGCGCGGCGGCCAGAGGAACCCCGAGTCC
CGGCCCAGGCCCCTGAGCTGGAGGGATGGAAAACTCCTCTGCAGCATCAGCCTCCTCGGAGGCAGGGAGCAGCCGCTCCCAGGAGATCGA
GGAGCTGGAGCGCTTCATCGACAGCTACGTGCTGGAGTACCAGGTGCAGGGGCTGCTGGCTGACAAGACGGAGGGTGATGGCGAGAGCGA
GAGGACCCAGTCCCACATCTCCCAGTGGACAGCGGACTGCAGCGAACCGCTGGACAGCAGCTGTTCCTTCTCCCGAGGGCGAGCCCCCCC
ACAGCAGAATGGCAGCAAAGACAACTCTCTGGACATGCTGGGCACGGACATCTGGGCGGCCAACACCTTCGATTCCTTCAGTGGTGCCAC
CTGGGACCTGCAGCCGGAAAAGCTGGACTTCACCCAGTTCCACCGCAAAGTCCGACACACGCCCAAGCAGCCCCTGCCACACATCGACCG
CGAAGGGTGTGGCAAAGGGAAGCTGGAAGATGGGGATGGCATCAACCTGAATGACATCGAGAAGGTCCTTCCAGCCTGGCAGGGCTACCA
CCCGATGCCCCATGAAGTGGAGATCGCACACACCAAGAAGCTGTTCCGCAGGAGGAGAAATGATCGAAGGCGGCAGCAGAGACCTCCGGG
GGGCAACAAGCCCCAACAGCATGGTGACCACCAGCCAGGCAGTGCCAAACACAACAGGGACCACCAGAAATCCTACCAGGGGGGCTCAGC
ACCCCACCCCTCAGGGAGGCCCACTCACCATGGCTACAGCCAGAACCGGCGCTGGCACCATGGCAACATGAAGCACCCACCAGGCGACAA
GGGGGAGGCAGGCGCACACCGCAATGCCAAAGAGACCATGACCATCGAGAACCCAAAACTGGAGGACACTGCAGGGGACACCGGGCACAG
CAGCCTTGAGGCCCCCCGCAGCCCTGACACCCTGGCCCCGGTGGCTTCTGAGCGGCTGCCCCCACAGCAGTCAGGGGGGCCAGAGGTTGA
GACAAAACGTAAAGACAGTATTCTTCCCGAGCGCATCGGGGAGCGGCCCAAAATTACCCTGCTCCAGTCTTCCAAAGACAGACTGCGGCG
AAGGCTAAAGGAAAAGGATGAAGTGGCCGTGGAGACGACCACTCCCCAGCAGAACAAGATGGACAAGCTGATCGAGATCCTGAACAGCAT
GCGGAACAACAGCAGCGACGTGGACACCAAGCTCACCACCTTCATGGAGGAGGCCCAGAACTCCACCAACTCCGAGGAGATGCTGGGCGA
GATCGTGCGCACAATCTACCAGAAGGCTGTGTCCGACCGCAGCTTCGCCTTCACCGCTGCCAAGCTCTGCGACAAGATGGCGCTCTTTAT
GGTGGAGGGGACCAAGTTCCGGAGCCTGCTCCTCAACATGCTGCAGGTGCCAGAGTTTGTAGCCTATTGGAGGAAAACACACCAAGGGAA
TCTTCAAACTCTTCTTCTCCACTGGCTCCTGCTGTGCTCCTGTCTCCATCACCTGTATAATGCTTCCTGCCATCCTGCCTTCCCCGTGGA
GTACAGCCATGCTGTCTGCTGCTTACAGCCAAGATTCTGGAAAGAAATGTCTCCTTTTTCCTCGTCATCAACCACTCATTTATTCAGCAA
GTGTTTCTTTTACACTTGCCTGTGCTGGGCATGGCAGCAATGCAGCAGTGAACAAAACCATCAGCCCTGCTCTCATGCAGCTTATAATCA
AGTAGAGAGACAGACATAAATGATTAATAGATGCTCCTGTAATGGTGGTTGTGAGGTGTGCTGCCACAGCCCAGCCACACACGCCAGTTC
CCTTCTCTGCACATGTACATGTCTGCTCATCCTTCCCACCTGAACTCATGTGCCACCTCACTTATGCCCCTTCCCAATGCCGCACCCACA
CAACAGGGTGTCCCTCTGTGCCCACAGCAGCCCTTGGGTATAACTGTTCCCCACAGAGGCTGAACCCCAAGGGCAGAGTCCAGGCCACAC
TCACCACGGAGACCCCTGCCTGGCACAGAGCCCAGCCCAGCAGAGATGCTCAGAAGATGAATGAAAGTCCCTGCTGAGATTGATCCAATC
TGTTTGTGAACATCTCTGGGGTCCAAGAATTCACGGCTTTCTTTTTCTTTAGAGAGCCTTTTGTTTCTTTTTGCCATTATATACTATATT
TGGGTTAGGGCACAACAATGTGAATATACTTAATACTGAACTCTACACTTGAAAATGGTTAAGATGGTAAAGTTTTAAGTTATATGTATT
TTGCCACAATTTTTTAAAATGCAGAGCATAGGTACAAAGAAGGAAAAAAAGGGGGCAAGGTCCATTTTATTGAGAAATAAAGAACAAAGG
GTTCAATTCAGAGAGGATTGGATTTTAAAACGTAATTTAGATTAGGGAAATGCAAATGAAAACCATAATAAGTAAGATACCACTTCACAT
CTGTTAGGATGGCTATTTTAAAACAACAAAAACAACCTGAAAATAAGTGTTGGCAAGGATGTGAAGAAATAGATACCCTTGTGCATTGCT
ATTGGGAACGTAAAATCATGCAGCCTTTGTTGAAAACAATGTGGTGGTTCCTCAAAAACTTAGTTATCATATGATCCCGCAGTTCCACTT
CTAGGAATATACCCAAAAGAATTGAAAGCAGGGACTCAAAGTGATATTTGTACACCAGTGTTTGTAGCAGTATTATTCACAATAGCCAAA
AGGTGGAAACAACCCAGATGTCCATGACAAGAGGAGTGGATAAACAAAATATGGTGAATATGTACAATGGAACATAATTCAGCTTTAAAA
AGGAATGAAATTCTGGTACATGTTATAACATAGATGAACCTTAAAAACATTATGCTAAGTGAAATAAGCCAGACACAGAAGGAAAAATAC
CAGATGATCCCACTTATATGAGGTACCTAGAATAGTGAAATTCATAGAGACAGAAAGTAGAAGGATGGTTGCCAGGGGCTGGAAGGAGGA
AGAACAGGGAGATACTGCTTAGTGGATGCAGAGTTTATGTTGAGGGTGATGAAAAAGTTCTGGAGATGGATGGTGGTGATGGCTGCACAA
CAGTGAGAATGTACTTCATACTATGGAACTCTGCACTTAAAAATGGTTAAAATGGATGTAGACATTTTATGTCTATTTTGCCATAACAAG
AAAGTAATTTGGGTGTATTTTAGAGATTTTAGAAAATACTGTAAGCACAAGAGGAAAAAAATTAAAATCATTCGCAATCACCAGGTAGAG
AC

>20229_20229_1_CTIF-C5orf56_CTIF_chr18_46288060_ENST00000256413_C5orf56_chr5_131785342_ENST00000337752_length(amino acids)=567AA_BP=455
MENSSAASASSEAGSSRSQEIEELERFIDSYVLEYQVQGLLADKTEGDGESERTQSHISQWTADCSEPLDSSCSFSRGRAPPQQNGSKDN
SLDMLGTDIWAANTFDSFSGATWDLQPEKLDFTQFHRKVRHTPKQPLPHIDREGCGKGKLEDGDGINLNDIEKVLPAWQGYHPMPHEVEI
AHTKKLFRRRRNDRRRQQRPPGGNKPQQHGDHQPGSAKHNRDHQKSYQGGSAPHPSGRPTHHGYSQNRRWHHGNMKHPPGDKGEAGAHRN
AKETMTIENPKLEDTAGDTGHSSLEAPRSPDTLAPVASERLPPQQSGGPEVETKRKDSILPERIGERPKITLLQSSKDRLRRRLKEKDEV
AVETTTPQQNKMDKLIEILNSMRNNSSDVDTKLTTFMEEAQNSTNSEEMLGEIVRTIYQKAVSDRSFAFTAAKLCDKMALFMVEGTKFRS
LLLNMLQVPEFVAYWRKTHQGNLQTLLLHWLLLCSCLHHLYNASCHPAFPVEYSHAVCCLQPRFWKEMSPFSSSSTTHLFSKCFFYTCLC
WAWQQCSSEQNHQPCSHAAYNQVERQT

--------------------------------------------------------------
>20229_20229_2_CTIF-C5orf56_CTIF_chr18_46288060_ENST00000256413_C5orf56_chr5_131785342_ENST00000378947_length(transcript)=2116nt_BP=1666nt
CTTTCCCTGTGTCAGATCAGGGATCATTTTTTTTCCTTCCTCTACTCCCTCCCCCCTACCCGCCCCTCCCTCCCTGTTTCCCTTCCCTCC
CTCCCTCCCCTCTCTGCTGGGTCTGTGCGCTGGGGCGCCCGATCCCCTCCGCAGCTGGGACGCTCCGAACTCGAGGCAGGAGTCGGCTCT
CCGGAGCCTCGTCCCTCCCTTCCCCTTCCCTGCCCCCTTCCCCCACCCCCGACTCGGGCTTGGCGCGGCGGCCAGAGGAACCCCGAGTCC
CGGCCCAGGCCCCTGAGCTGGAGGGATGGAAAACTCCTCTGCAGCATCAGCCTCCTCGGAGGCAGGGAGCAGCCGCTCCCAGGAGATCGA
GGAGCTGGAGCGCTTCATCGACAGCTACGTGCTGGAGTACCAGGTGCAGGGGCTGCTGGCTGACAAGACGGAGGGTGATGGCGAGAGCGA
GAGGACCCAGTCCCACATCTCCCAGTGGACAGCGGACTGCAGCGAACCGCTGGACAGCAGCTGTTCCTTCTCCCGAGGGCGAGCCCCCCC
ACAGCAGAATGGCAGCAAAGACAACTCTCTGGACATGCTGGGCACGGACATCTGGGCGGCCAACACCTTCGATTCCTTCAGTGGTGCCAC
CTGGGACCTGCAGCCGGAAAAGCTGGACTTCACCCAGTTCCACCGCAAAGTCCGACACACGCCCAAGCAGCCCCTGCCACACATCGACCG
CGAAGGGTGTGGCAAAGGGAAGCTGGAAGATGGGGATGGCATCAACCTGAATGACATCGAGAAGGTCCTTCCAGCCTGGCAGGGCTACCA
CCCGATGCCCCATGAAGTGGAGATCGCACACACCAAGAAGCTGTTCCGCAGGAGGAGAAATGATCGAAGGCGGCAGCAGAGACCTCCGGG
GGGCAACAAGCCCCAACAGCATGGTGACCACCAGCCAGGCAGTGCCAAACACAACAGGGACCACCAGAAATCCTACCAGGGGGGCTCAGC
ACCCCACCCCTCAGGGAGGCCCACTCACCATGGCTACAGCCAGAACCGGCGCTGGCACCATGGCAACATGAAGCACCCACCAGGCGACAA
GGGGGAGGCAGGCGCACACCGCAATGCCAAAGAGACCATGACCATCGAGAACCCAAAACTGGAGGACACTGCAGGGGACACCGGGCACAG
CAGCCTTGAGGCCCCCCGCAGCCCTGACACCCTGGCCCCGGTGGCTTCTGAGCGGCTGCCCCCACAGCAGTCAGGGGGGCCAGAGGTTGA
GACAAAACGTAAAGACAGTATTCTTCCCGAGCGCATCGGGGAGCGGCCCAAAATTACCCTGCTCCAGTCTTCCAAAGACAGACTGCGGCG
AAGGCTAAAGGAAAAGGATGAAGTGGCCGTGGAGACGACCACTCCCCAGCAGAACAAGATGGACAAGCTGATCGAGATCCTGAACAGCAT
GCGGAACAACAGCAGCGACGTGGACACCAAGCTCACCACCTTCATGGAGGAGGCCCAGAACTCCACCAACTCCGAGGAGATGCTGGGCGA
GATCGTGCGCACAATCTACCAGAAGGCTGTGTCCGACCGCAGCTTCGCCTTCACCGCTGCCAAGCTCTGCGACAAGATGGCGCTCTTTAT
GGTGGAGGGGACCAAGTTCCGGAGCCTGCTCCTCAACATGCTGCAGGTGCCAGAGTTTGTAGCCTATTGGAGGAAAACACACCAAGCCTA
CGCCACTCTGTGCCCTTTAGCCAAGGAAGCCCAGCTGAGGCCCCGCAGCGTCCCTGCCCAGCAGAGCTACAGGAGGCCCGAGGCCCCTTC
CTGTTCACTCTTGCTCTATAGACGCCACGCTGCAAAGCAGATGTGCAGGGACACCACCTGAAGACCCAGCCTGCAGCTCAGCCCTACACA
CTGTGGATGGTGGAGATCCCAGAGGGCCAAGAGAAGCTTATTGAGACTTCTCTGCACTGCCCCTCCCACAGCAGGAGGTTCATGGCCCAT
GCATTTCTGGGAGGGTTGACAGGGCCCAGGTTGTGGAATACCTGTCTGTGAGCCCCATGTCCTGTCTTGTCCCAGCTGCCTGTAGTTTGA
CAGAGTATGCTAGAGGTCAGCCATTGCTAGGGAGGCTGCCACTAAC

>20229_20229_2_CTIF-C5orf56_CTIF_chr18_46288060_ENST00000256413_C5orf56_chr5_131785342_ENST00000378947_length(amino acids)=521AA_BP=455
MENSSAASASSEAGSSRSQEIEELERFIDSYVLEYQVQGLLADKTEGDGESERTQSHISQWTADCSEPLDSSCSFSRGRAPPQQNGSKDN
SLDMLGTDIWAANTFDSFSGATWDLQPEKLDFTQFHRKVRHTPKQPLPHIDREGCGKGKLEDGDGINLNDIEKVLPAWQGYHPMPHEVEI
AHTKKLFRRRRNDRRRQQRPPGGNKPQQHGDHQPGSAKHNRDHQKSYQGGSAPHPSGRPTHHGYSQNRRWHHGNMKHPPGDKGEAGAHRN
AKETMTIENPKLEDTAGDTGHSSLEAPRSPDTLAPVASERLPPQQSGGPEVETKRKDSILPERIGERPKITLLQSSKDRLRRRLKEKDEV
AVETTTPQQNKMDKLIEILNSMRNNSSDVDTKLTTFMEEAQNSTNSEEMLGEIVRTIYQKAVSDRSFAFTAAKLCDKMALFMVEGTKFRS
LLLNMLQVPEFVAYWRKTHQAYATLCPLAKEAQLRPRSVPAQQSYRRPEAPSCSLLLYRRHAAKQMCRDTT

--------------------------------------------------------------
>20229_20229_3_CTIF-C5orf56_CTIF_chr18_46288060_ENST00000256413_C5orf56_chr5_131785342_ENST00000378953_length(transcript)=2084nt_BP=1666nt
CTTTCCCTGTGTCAGATCAGGGATCATTTTTTTTCCTTCCTCTACTCCCTCCCCCCTACCCGCCCCTCCCTCCCTGTTTCCCTTCCCTCC
CTCCCTCCCCTCTCTGCTGGGTCTGTGCGCTGGGGCGCCCGATCCCCTCCGCAGCTGGGACGCTCCGAACTCGAGGCAGGAGTCGGCTCT
CCGGAGCCTCGTCCCTCCCTTCCCCTTCCCTGCCCCCTTCCCCCACCCCCGACTCGGGCTTGGCGCGGCGGCCAGAGGAACCCCGAGTCC
CGGCCCAGGCCCCTGAGCTGGAGGGATGGAAAACTCCTCTGCAGCATCAGCCTCCTCGGAGGCAGGGAGCAGCCGCTCCCAGGAGATCGA
GGAGCTGGAGCGCTTCATCGACAGCTACGTGCTGGAGTACCAGGTGCAGGGGCTGCTGGCTGACAAGACGGAGGGTGATGGCGAGAGCGA
GAGGACCCAGTCCCACATCTCCCAGTGGACAGCGGACTGCAGCGAACCGCTGGACAGCAGCTGTTCCTTCTCCCGAGGGCGAGCCCCCCC
ACAGCAGAATGGCAGCAAAGACAACTCTCTGGACATGCTGGGCACGGACATCTGGGCGGCCAACACCTTCGATTCCTTCAGTGGTGCCAC
CTGGGACCTGCAGCCGGAAAAGCTGGACTTCACCCAGTTCCACCGCAAAGTCCGACACACGCCCAAGCAGCCCCTGCCACACATCGACCG
CGAAGGGTGTGGCAAAGGGAAGCTGGAAGATGGGGATGGCATCAACCTGAATGACATCGAGAAGGTCCTTCCAGCCTGGCAGGGCTACCA
CCCGATGCCCCATGAAGTGGAGATCGCACACACCAAGAAGCTGTTCCGCAGGAGGAGAAATGATCGAAGGCGGCAGCAGAGACCTCCGGG
GGGCAACAAGCCCCAACAGCATGGTGACCACCAGCCAGGCAGTGCCAAACACAACAGGGACCACCAGAAATCCTACCAGGGGGGCTCAGC
ACCCCACCCCTCAGGGAGGCCCACTCACCATGGCTACAGCCAGAACCGGCGCTGGCACCATGGCAACATGAAGCACCCACCAGGCGACAA
GGGGGAGGCAGGCGCACACCGCAATGCCAAAGAGACCATGACCATCGAGAACCCAAAACTGGAGGACACTGCAGGGGACACCGGGCACAG
CAGCCTTGAGGCCCCCCGCAGCCCTGACACCCTGGCCCCGGTGGCTTCTGAGCGGCTGCCCCCACAGCAGTCAGGGGGGCCAGAGGTTGA
GACAAAACGTAAAGACAGTATTCTTCCCGAGCGCATCGGGGAGCGGCCCAAAATTACCCTGCTCCAGTCTTCCAAAGACAGACTGCGGCG
AAGGCTAAAGGAAAAGGATGAAGTGGCCGTGGAGACGACCACTCCCCAGCAGAACAAGATGGACAAGCTGATCGAGATCCTGAACAGCAT
GCGGAACAACAGCAGCGACGTGGACACCAAGCTCACCACCTTCATGGAGGAGGCCCAGAACTCCACCAACTCCGAGGAGATGCTGGGCGA
GATCGTGCGCACAATCTACCAGAAGGCTGTGTCCGACCGCAGCTTCGCCTTCACCGCTGCCAAGCTCTGCGACAAGATGGCGCTCTTTAT
GGTGGAGGGGACCAAGTTCCGGAGCCTGCTCCTCAACATGCTGCAGGTGCCAGAGTTTGTAGCCTATTGGAGGAAAACACACCAAGATCA
CCTCTGCAGCCTGCACAGCCGGGCCTTTGGACTCCTGGATGCTAGAGTGACCTGGGCGCTGAGGAGGGCCCCCGAGCCAGTACCAGGAAA
GGATAGACTCCTGCTTGCAGCATTCCCAGCAGAGGCATCGCCTGTGGACACCGCGTCTGTGTCTGTATATGGCAGAGCTCCCAGATATAT
GCACAAGGGAGTGAAAAAATGTGTTTGCACCCCAGTCTCTAAAAATTCAACAGCCTGGTTACTTCTGGGTGGTATATCGTAGGTGGCTTT
AATACGTGTTATTTGCTCATCTGTATTTCTTACTCTTTGCACAATTAAACCATGTTCCTTTTACTTATGTACATTTTTAATAAAAGAAAG
TTGTTAATGACTCA

>20229_20229_3_CTIF-C5orf56_CTIF_chr18_46288060_ENST00000256413_C5orf56_chr5_131785342_ENST00000378953_length(amino acids)=558AA_BP=455
MENSSAASASSEAGSSRSQEIEELERFIDSYVLEYQVQGLLADKTEGDGESERTQSHISQWTADCSEPLDSSCSFSRGRAPPQQNGSKDN
SLDMLGTDIWAANTFDSFSGATWDLQPEKLDFTQFHRKVRHTPKQPLPHIDREGCGKGKLEDGDGINLNDIEKVLPAWQGYHPMPHEVEI
AHTKKLFRRRRNDRRRQQRPPGGNKPQQHGDHQPGSAKHNRDHQKSYQGGSAPHPSGRPTHHGYSQNRRWHHGNMKHPPGDKGEAGAHRN
AKETMTIENPKLEDTAGDTGHSSLEAPRSPDTLAPVASERLPPQQSGGPEVETKRKDSILPERIGERPKITLLQSSKDRLRRRLKEKDEV
AVETTTPQQNKMDKLIEILNSMRNNSSDVDTKLTTFMEEAQNSTNSEEMLGEIVRTIYQKAVSDRSFAFTAAKLCDKMALFMVEGTKFRS
LLLNMLQVPEFVAYWRKTHQDHLCSLHSRAFGLLDARVTWALRRAPEPVPGKDRLLLAAFPAEASPVDTASVSVYGRAPRYMHKGVKKCV
CTPVSKNSTAWLLLGGIS

--------------------------------------------------------------
>20229_20229_4_CTIF-C5orf56_CTIF_chr18_46288060_ENST00000256413_C5orf56_chr5_131785342_ENST00000407797_length(transcript)=2575nt_BP=1666nt
CTTTCCCTGTGTCAGATCAGGGATCATTTTTTTTCCTTCCTCTACTCCCTCCCCCCTACCCGCCCCTCCCTCCCTGTTTCCCTTCCCTCC
CTCCCTCCCCTCTCTGCTGGGTCTGTGCGCTGGGGCGCCCGATCCCCTCCGCAGCTGGGACGCTCCGAACTCGAGGCAGGAGTCGGCTCT
CCGGAGCCTCGTCCCTCCCTTCCCCTTCCCTGCCCCCTTCCCCCACCCCCGACTCGGGCTTGGCGCGGCGGCCAGAGGAACCCCGAGTCC
CGGCCCAGGCCCCTGAGCTGGAGGGATGGAAAACTCCTCTGCAGCATCAGCCTCCTCGGAGGCAGGGAGCAGCCGCTCCCAGGAGATCGA
GGAGCTGGAGCGCTTCATCGACAGCTACGTGCTGGAGTACCAGGTGCAGGGGCTGCTGGCTGACAAGACGGAGGGTGATGGCGAGAGCGA
GAGGACCCAGTCCCACATCTCCCAGTGGACAGCGGACTGCAGCGAACCGCTGGACAGCAGCTGTTCCTTCTCCCGAGGGCGAGCCCCCCC
ACAGCAGAATGGCAGCAAAGACAACTCTCTGGACATGCTGGGCACGGACATCTGGGCGGCCAACACCTTCGATTCCTTCAGTGGTGCCAC
CTGGGACCTGCAGCCGGAAAAGCTGGACTTCACCCAGTTCCACCGCAAAGTCCGACACACGCCCAAGCAGCCCCTGCCACACATCGACCG
CGAAGGGTGTGGCAAAGGGAAGCTGGAAGATGGGGATGGCATCAACCTGAATGACATCGAGAAGGTCCTTCCAGCCTGGCAGGGCTACCA
CCCGATGCCCCATGAAGTGGAGATCGCACACACCAAGAAGCTGTTCCGCAGGAGGAGAAATGATCGAAGGCGGCAGCAGAGACCTCCGGG
GGGCAACAAGCCCCAACAGCATGGTGACCACCAGCCAGGCAGTGCCAAACACAACAGGGACCACCAGAAATCCTACCAGGGGGGCTCAGC
ACCCCACCCCTCAGGGAGGCCCACTCACCATGGCTACAGCCAGAACCGGCGCTGGCACCATGGCAACATGAAGCACCCACCAGGCGACAA
GGGGGAGGCAGGCGCACACCGCAATGCCAAAGAGACCATGACCATCGAGAACCCAAAACTGGAGGACACTGCAGGGGACACCGGGCACAG
CAGCCTTGAGGCCCCCCGCAGCCCTGACACCCTGGCCCCGGTGGCTTCTGAGCGGCTGCCCCCACAGCAGTCAGGGGGGCCAGAGGTTGA
GACAAAACGTAAAGACAGTATTCTTCCCGAGCGCATCGGGGAGCGGCCCAAAATTACCCTGCTCCAGTCTTCCAAAGACAGACTGCGGCG
AAGGCTAAAGGAAAAGGATGAAGTGGCCGTGGAGACGACCACTCCCCAGCAGAACAAGATGGACAAGCTGATCGAGATCCTGAACAGCAT
GCGGAACAACAGCAGCGACGTGGACACCAAGCTCACCACCTTCATGGAGGAGGCCCAGAACTCCACCAACTCCGAGGAGATGCTGGGCGA
GATCGTGCGCACAATCTACCAGAAGGCTGTGTCCGACCGCAGCTTCGCCTTCACCGCTGCCAAGCTCTGCGACAAGATGGCGCTCTTTAT
GGTGGAGGGGACCAAGTTCCGGAGCCTGCTCCTCAACATGCTGCAGGTGCCAGAGTTTGTAGCCTATTGGAGGAAAACACACCAAGCCCC
GAACAGCACAGTGAATGGATAGGGCAGCAGATGAGCTCTGCCCCACGCCGGCCCTGTTTCAGAACAGCACTCCAGAGTGCCGCACTGCTT
GCTGAACCACAGCTGTTACTGCAGATTGAGGAGCCTCAGAGGGAACAGAAGATAAAGATCATTATGGAATTTAGGATTGCAGGACATTCT
TTGACATTTCATAACAGCCAGGGGAGATCAACTGTGGTCAGGGGACAGGGGCAGGAAGAAACCATGGCCAAGGCCTGTCTGGCAGGACTT
GAAGGGGCAGAGGGACCCTTGCAAATGACCCTGCCTGGAACCCACCCCCAGTTGGCCCCTGTATAGCACTGATCCAGCTGGGGCTTTTAT
CCCAGGATACCCTCTTCAGGGATGCCTGTATTTGTTGATTATCTGCCATATGCCTGGTCACTGCAGAATACAAGGAAGAAAATAGCCTTC
AGCAGAAGCTGAGACAGGAGCCTAGAGGATGGACAGTAAGGAGTCGAAGGCTCAGGATGAGGCTTTCCTGACTTTCTCCCCTAGAGGACT
GATGTTCTCTACTGGTACAGACCTTGTTTTATTCATCCTTATGTCCCTAACCTGGAATGGGCCCAGGGTGACAGTTATAATAAGTGTTTG
TCAAGTGAGCAAGTGTGTGGAGTGTGCATTGTAGAGAGTAAGGTCTCTACAGGATCCTGCTGGAGAGGCAGCCCACTGGGCTCACCACTT
CTCCAGAGGAGGGACTGGTCCCTTGCCAGACAGCCCTGCCAGCTGGAGCAGGCTTCCTCAGGGGTGCCTGGAGCTGTTGACCATGGCTGT
TGCCCTCTGGCCCCTCTTGGGAAGAGCAACCTGTCAGGTGTTAAAGACGGTCTTC

>20229_20229_4_CTIF-C5orf56_CTIF_chr18_46288060_ENST00000256413_C5orf56_chr5_131785342_ENST00000407797_length(amino acids)=478AA_BP=455
MENSSAASASSEAGSSRSQEIEELERFIDSYVLEYQVQGLLADKTEGDGESERTQSHISQWTADCSEPLDSSCSFSRGRAPPQQNGSKDN
SLDMLGTDIWAANTFDSFSGATWDLQPEKLDFTQFHRKVRHTPKQPLPHIDREGCGKGKLEDGDGINLNDIEKVLPAWQGYHPMPHEVEI
AHTKKLFRRRRNDRRRQQRPPGGNKPQQHGDHQPGSAKHNRDHQKSYQGGSAPHPSGRPTHHGYSQNRRWHHGNMKHPPGDKGEAGAHRN
AKETMTIENPKLEDTAGDTGHSSLEAPRSPDTLAPVASERLPPQQSGGPEVETKRKDSILPERIGERPKITLLQSSKDRLRRRLKEKDEV
AVETTTPQQNKMDKLIEILNSMRNNSSDVDTKLTTFMEEAQNSTNSEEMLGEIVRTIYQKAVSDRSFAFTAAKLCDKMALFMVEGTKFRS
LLLNMLQVPEFVAYWRKTHQAPNSTVNG

--------------------------------------------------------------
>20229_20229_5_CTIF-C5orf56_CTIF_chr18_46288060_ENST00000382998_C5orf56_chr5_131785342_ENST00000337752_length(transcript)=3480nt_BP=1634nt
CTGTGCGCTGGGGCGCCCGATCCCCTCCGCAGCTGGGACGCTCCGAACTCGAGGCAGGAGTCGGCTCTCCGGAGCCTCGTCCCTCCCTTC
CCCTTCCCTGCCCCCTTCCCCCACCCCCGACTCGGGCTTGGCGCGGCGGCCAGAGGAACCCCGAGCCCGCATTTGCTGCATCGAGCAGTT
GGTTTAGTATCAGCCAAACTTGCAGCTGTTCAGACCGCGCTCCGCCGAGTCCCGGCCCAGGCCCCTGAGCTGGAGGGATGGAAAACTCCT
CTGCAGCATCAGCCTCCTCGGAGGCAGGGAGCAGCCGCTCCCAGGAGATCGAGGAGCTGGAGCGCTTCATCGACAGCTACGTGCTGGAGT
ACCAGGTGCAGGGGCTGCTGGCTGACAAGACGGAGGGTGATGGCGAGAGCGAGAGGACCCAGTCCCACATCTCCCAGTGGACAGCGGACT
GCAGCGAACCGCTGGACAGCAGCTGTTCCTTCTCCCGAGGGCGAGCCCCCCCACAGCAGAATGGCAGCAAAGACAACTCTCTGGACATGC
TGGGCACGGACATCTGGGCGGCCAACACCTTCGATTCCTTCAGTGGTGCCACCTGGGACCTGCAGCCGGAAAAGCTGGACTTCACCCAGT
TCCACCGCAAAGTCCGACACACGCCCAAGCAGCCCCTGCCACACATCGACCGCGAAGGGTGTGGCAAAGGGAAGCTGGAAGATGGGGATG
GCATCAACCTGAATGACATCGAGAAGGTCCTTCCAGCCTGGCAGGGCTACCACCCGATGCCCCATGAAGTGGAGATCGCACACACCAAGA
AGCTGTTCCGCAGGAGGAGAAATGATCGAAGGCGGCAGCAGAGACCTCCGGGGGGCAACAAGCCCCAACAGCATGGTGACCACCAGCCAG
GCAGTGCCAAACACAACAGGGACCACCAGAAATCCTACCAGGGGGGCTCAGCACCCCACCCCTCAGGGAGGCCCACTCACCATGGCTACA
GCCAGAACCGGCGCTGGCACCATGGCAACATGAAGCACCCACCAGGCGACAAGGGGGAGGCAGGCGCACACCGCAATGCCAAAGAGACCA
TGACCATCGAGAACCCAAAACTGGAGGACACTGCAGGGGACACCGGGCACAGCAGCCTTGAGGCCCCCCGCAGCCCTGACACCCTGGCCC
CGGTGGCTTCTGAGCGGCTGCCCCCACAGCAGTCAGGGGGGCCAGAGGTTGAGACAAAACGTAAAGACAGTATTCTTCCCGAGCGCATCG
GGGAGCGGCCCAAAATTACCCTGCTCCAGTCTTCCAAAGACAGACTGCGGCGAAGGCTAAAGGAAAAGGTACCGGATGAAGTGGCCGTGG
AGACGACCACTCCCCAGCAGAACAAGATGGACAAGCTGATCGAGATCCTGAACAGCATGCGGAACAACAGCAGCGACGTGGACACCAAGC
TCACCACCTTCATGGAGGAGGCCCAGAACTCCACCAACTCCGAGGAGATGCTGGGCGAGATCGTGCGCACAATCTACCAGAAGGCTGTGT
CCGACCGCAGCTTCGCCTTCACCGCTGCCAAGCTCTGCGACAAGATGGCGCTCTTTATGGTGGAGGGGACCAAGTTCCGGAGCCTGCTCC
TCAACATGCTGCAGGTGCCAGAGTTTGTAGCCTATTGGAGGAAAACACACCAAGGGAATCTTCAAACTCTTCTTCTCCACTGGCTCCTGC
TGTGCTCCTGTCTCCATCACCTGTATAATGCTTCCTGCCATCCTGCCTTCCCCGTGGAGTACAGCCATGCTGTCTGCTGCTTACAGCCAA
GATTCTGGAAAGAAATGTCTCCTTTTTCCTCGTCATCAACCACTCATTTATTCAGCAAGTGTTTCTTTTACACTTGCCTGTGCTGGGCAT
GGCAGCAATGCAGCAGTGAACAAAACCATCAGCCCTGCTCTCATGCAGCTTATAATCAAGTAGAGAGACAGACATAAATGATTAATAGAT
GCTCCTGTAATGGTGGTTGTGAGGTGTGCTGCCACAGCCCAGCCACACACGCCAGTTCCCTTCTCTGCACATGTACATGTCTGCTCATCC
TTCCCACCTGAACTCATGTGCCACCTCACTTATGCCCCTTCCCAATGCCGCACCCACACAACAGGGTGTCCCTCTGTGCCCACAGCAGCC
CTTGGGTATAACTGTTCCCCACAGAGGCTGAACCCCAAGGGCAGAGTCCAGGCCACACTCACCACGGAGACCCCTGCCTGGCACAGAGCC
CAGCCCAGCAGAGATGCTCAGAAGATGAATGAAAGTCCCTGCTGAGATTGATCCAATCTGTTTGTGAACATCTCTGGGGTCCAAGAATTC
ACGGCTTTCTTTTTCTTTAGAGAGCCTTTTGTTTCTTTTTGCCATTATATACTATATTTGGGTTAGGGCACAACAATGTGAATATACTTA
ATACTGAACTCTACACTTGAAAATGGTTAAGATGGTAAAGTTTTAAGTTATATGTATTTTGCCACAATTTTTTAAAATGCAGAGCATAGG
TACAAAGAAGGAAAAAAAGGGGGCAAGGTCCATTTTATTGAGAAATAAAGAACAAAGGGTTCAATTCAGAGAGGATTGGATTTTAAAACG
TAATTTAGATTAGGGAAATGCAAATGAAAACCATAATAAGTAAGATACCACTTCACATCTGTTAGGATGGCTATTTTAAAACAACAAAAA
CAACCTGAAAATAAGTGTTGGCAAGGATGTGAAGAAATAGATACCCTTGTGCATTGCTATTGGGAACGTAAAATCATGCAGCCTTTGTTG
AAAACAATGTGGTGGTTCCTCAAAAACTTAGTTATCATATGATCCCGCAGTTCCACTTCTAGGAATATACCCAAAAGAATTGAAAGCAGG
GACTCAAAGTGATATTTGTACACCAGTGTTTGTAGCAGTATTATTCACAATAGCCAAAAGGTGGAAACAACCCAGATGTCCATGACAAGA
GGAGTGGATAAACAAAATATGGTGAATATGTACAATGGAACATAATTCAGCTTTAAAAAGGAATGAAATTCTGGTACATGTTATAACATA
GATGAACCTTAAAAACATTATGCTAAGTGAAATAAGCCAGACACAGAAGGAAAAATACCAGATGATCCCACTTATATGAGGTACCTAGAA
TAGTGAAATTCATAGAGACAGAAAGTAGAAGGATGGTTGCCAGGGGCTGGAAGGAGGAAGAACAGGGAGATACTGCTTAGTGGATGCAGA
GTTTATGTTGAGGGTGATGAAAAAGTTCTGGAGATGGATGGTGGTGATGGCTGCACAACAGTGAGAATGTACTTCATACTATGGAACTCT
GCACTTAAAAATGGTTAAAATGGATGTAGACATTTTATGTCTATTTTGCCATAACAAGAAAGTAATTTGGGTGTATTTTAGAGATTTTAG
AAAATACTGTAAGCACAAGAGGAAAAAAATTAAAATCATTCGCAATCACCAGGTAGAGAC

>20229_20229_5_CTIF-C5orf56_CTIF_chr18_46288060_ENST00000382998_C5orf56_chr5_131785342_ENST00000337752_length(amino acids)=569AA_BP=457
MENSSAASASSEAGSSRSQEIEELERFIDSYVLEYQVQGLLADKTEGDGESERTQSHISQWTADCSEPLDSSCSFSRGRAPPQQNGSKDN
SLDMLGTDIWAANTFDSFSGATWDLQPEKLDFTQFHRKVRHTPKQPLPHIDREGCGKGKLEDGDGINLNDIEKVLPAWQGYHPMPHEVEI
AHTKKLFRRRRNDRRRQQRPPGGNKPQQHGDHQPGSAKHNRDHQKSYQGGSAPHPSGRPTHHGYSQNRRWHHGNMKHPPGDKGEAGAHRN
AKETMTIENPKLEDTAGDTGHSSLEAPRSPDTLAPVASERLPPQQSGGPEVETKRKDSILPERIGERPKITLLQSSKDRLRRRLKEKVPD
EVAVETTTPQQNKMDKLIEILNSMRNNSSDVDTKLTTFMEEAQNSTNSEEMLGEIVRTIYQKAVSDRSFAFTAAKLCDKMALFMVEGTKF
RSLLLNMLQVPEFVAYWRKTHQGNLQTLLLHWLLLCSCLHHLYNASCHPAFPVEYSHAVCCLQPRFWKEMSPFSSSSTTHLFSKCFFYTC
LCWAWQQCSSEQNHQPCSHAAYNQVERQT

--------------------------------------------------------------
>20229_20229_6_CTIF-C5orf56_CTIF_chr18_46288060_ENST00000382998_C5orf56_chr5_131785342_ENST00000378947_length(transcript)=2084nt_BP=1634nt
CTGTGCGCTGGGGCGCCCGATCCCCTCCGCAGCTGGGACGCTCCGAACTCGAGGCAGGAGTCGGCTCTCCGGAGCCTCGTCCCTCCCTTC
CCCTTCCCTGCCCCCTTCCCCCACCCCCGACTCGGGCTTGGCGCGGCGGCCAGAGGAACCCCGAGCCCGCATTTGCTGCATCGAGCAGTT
GGTTTAGTATCAGCCAAACTTGCAGCTGTTCAGACCGCGCTCCGCCGAGTCCCGGCCCAGGCCCCTGAGCTGGAGGGATGGAAAACTCCT
CTGCAGCATCAGCCTCCTCGGAGGCAGGGAGCAGCCGCTCCCAGGAGATCGAGGAGCTGGAGCGCTTCATCGACAGCTACGTGCTGGAGT
ACCAGGTGCAGGGGCTGCTGGCTGACAAGACGGAGGGTGATGGCGAGAGCGAGAGGACCCAGTCCCACATCTCCCAGTGGACAGCGGACT
GCAGCGAACCGCTGGACAGCAGCTGTTCCTTCTCCCGAGGGCGAGCCCCCCCACAGCAGAATGGCAGCAAAGACAACTCTCTGGACATGC
TGGGCACGGACATCTGGGCGGCCAACACCTTCGATTCCTTCAGTGGTGCCACCTGGGACCTGCAGCCGGAAAAGCTGGACTTCACCCAGT
TCCACCGCAAAGTCCGACACACGCCCAAGCAGCCCCTGCCACACATCGACCGCGAAGGGTGTGGCAAAGGGAAGCTGGAAGATGGGGATG
GCATCAACCTGAATGACATCGAGAAGGTCCTTCCAGCCTGGCAGGGCTACCACCCGATGCCCCATGAAGTGGAGATCGCACACACCAAGA
AGCTGTTCCGCAGGAGGAGAAATGATCGAAGGCGGCAGCAGAGACCTCCGGGGGGCAACAAGCCCCAACAGCATGGTGACCACCAGCCAG
GCAGTGCCAAACACAACAGGGACCACCAGAAATCCTACCAGGGGGGCTCAGCACCCCACCCCTCAGGGAGGCCCACTCACCATGGCTACA
GCCAGAACCGGCGCTGGCACCATGGCAACATGAAGCACCCACCAGGCGACAAGGGGGAGGCAGGCGCACACCGCAATGCCAAAGAGACCA
TGACCATCGAGAACCCAAAACTGGAGGACACTGCAGGGGACACCGGGCACAGCAGCCTTGAGGCCCCCCGCAGCCCTGACACCCTGGCCC
CGGTGGCTTCTGAGCGGCTGCCCCCACAGCAGTCAGGGGGGCCAGAGGTTGAGACAAAACGTAAAGACAGTATTCTTCCCGAGCGCATCG
GGGAGCGGCCCAAAATTACCCTGCTCCAGTCTTCCAAAGACAGACTGCGGCGAAGGCTAAAGGAAAAGGTACCGGATGAAGTGGCCGTGG
AGACGACCACTCCCCAGCAGAACAAGATGGACAAGCTGATCGAGATCCTGAACAGCATGCGGAACAACAGCAGCGACGTGGACACCAAGC
TCACCACCTTCATGGAGGAGGCCCAGAACTCCACCAACTCCGAGGAGATGCTGGGCGAGATCGTGCGCACAATCTACCAGAAGGCTGTGT
CCGACCGCAGCTTCGCCTTCACCGCTGCCAAGCTCTGCGACAAGATGGCGCTCTTTATGGTGGAGGGGACCAAGTTCCGGAGCCTGCTCC
TCAACATGCTGCAGGTGCCAGAGTTTGTAGCCTATTGGAGGAAAACACACCAAGCCTACGCCACTCTGTGCCCTTTAGCCAAGGAAGCCC
AGCTGAGGCCCCGCAGCGTCCCTGCCCAGCAGAGCTACAGGAGGCCCGAGGCCCCTTCCTGTTCACTCTTGCTCTATAGACGCCACGCTG
CAAAGCAGATGTGCAGGGACACCACCTGAAGACCCAGCCTGCAGCTCAGCCCTACACACTGTGGATGGTGGAGATCCCAGAGGGCCAAGA
GAAGCTTATTGAGACTTCTCTGCACTGCCCCTCCCACAGCAGGAGGTTCATGGCCCATGCATTTCTGGGAGGGTTGACAGGGCCCAGGTT
GTGGAATACCTGTCTGTGAGCCCCATGTCCTGTCTTGTCCCAGCTGCCTGTAGTTTGACAGAGTATGCTAGAGGTCAGCCATTGCTAGGG
AGGCTGCCACTAAC

>20229_20229_6_CTIF-C5orf56_CTIF_chr18_46288060_ENST00000382998_C5orf56_chr5_131785342_ENST00000378947_length(amino acids)=523AA_BP=457
MENSSAASASSEAGSSRSQEIEELERFIDSYVLEYQVQGLLADKTEGDGESERTQSHISQWTADCSEPLDSSCSFSRGRAPPQQNGSKDN
SLDMLGTDIWAANTFDSFSGATWDLQPEKLDFTQFHRKVRHTPKQPLPHIDREGCGKGKLEDGDGINLNDIEKVLPAWQGYHPMPHEVEI
AHTKKLFRRRRNDRRRQQRPPGGNKPQQHGDHQPGSAKHNRDHQKSYQGGSAPHPSGRPTHHGYSQNRRWHHGNMKHPPGDKGEAGAHRN
AKETMTIENPKLEDTAGDTGHSSLEAPRSPDTLAPVASERLPPQQSGGPEVETKRKDSILPERIGERPKITLLQSSKDRLRRRLKEKVPD
EVAVETTTPQQNKMDKLIEILNSMRNNSSDVDTKLTTFMEEAQNSTNSEEMLGEIVRTIYQKAVSDRSFAFTAAKLCDKMALFMVEGTKF
RSLLLNMLQVPEFVAYWRKTHQAYATLCPLAKEAQLRPRSVPAQQSYRRPEAPSCSLLLYRRHAAKQMCRDTT

--------------------------------------------------------------
>20229_20229_7_CTIF-C5orf56_CTIF_chr18_46288060_ENST00000382998_C5orf56_chr5_131785342_ENST00000378953_length(transcript)=2052nt_BP=1634nt
CTGTGCGCTGGGGCGCCCGATCCCCTCCGCAGCTGGGACGCTCCGAACTCGAGGCAGGAGTCGGCTCTCCGGAGCCTCGTCCCTCCCTTC
CCCTTCCCTGCCCCCTTCCCCCACCCCCGACTCGGGCTTGGCGCGGCGGCCAGAGGAACCCCGAGCCCGCATTTGCTGCATCGAGCAGTT
GGTTTAGTATCAGCCAAACTTGCAGCTGTTCAGACCGCGCTCCGCCGAGTCCCGGCCCAGGCCCCTGAGCTGGAGGGATGGAAAACTCCT
CTGCAGCATCAGCCTCCTCGGAGGCAGGGAGCAGCCGCTCCCAGGAGATCGAGGAGCTGGAGCGCTTCATCGACAGCTACGTGCTGGAGT
ACCAGGTGCAGGGGCTGCTGGCTGACAAGACGGAGGGTGATGGCGAGAGCGAGAGGACCCAGTCCCACATCTCCCAGTGGACAGCGGACT
GCAGCGAACCGCTGGACAGCAGCTGTTCCTTCTCCCGAGGGCGAGCCCCCCCACAGCAGAATGGCAGCAAAGACAACTCTCTGGACATGC
TGGGCACGGACATCTGGGCGGCCAACACCTTCGATTCCTTCAGTGGTGCCACCTGGGACCTGCAGCCGGAAAAGCTGGACTTCACCCAGT
TCCACCGCAAAGTCCGACACACGCCCAAGCAGCCCCTGCCACACATCGACCGCGAAGGGTGTGGCAAAGGGAAGCTGGAAGATGGGGATG
GCATCAACCTGAATGACATCGAGAAGGTCCTTCCAGCCTGGCAGGGCTACCACCCGATGCCCCATGAAGTGGAGATCGCACACACCAAGA
AGCTGTTCCGCAGGAGGAGAAATGATCGAAGGCGGCAGCAGAGACCTCCGGGGGGCAACAAGCCCCAACAGCATGGTGACCACCAGCCAG
GCAGTGCCAAACACAACAGGGACCACCAGAAATCCTACCAGGGGGGCTCAGCACCCCACCCCTCAGGGAGGCCCACTCACCATGGCTACA
GCCAGAACCGGCGCTGGCACCATGGCAACATGAAGCACCCACCAGGCGACAAGGGGGAGGCAGGCGCACACCGCAATGCCAAAGAGACCA
TGACCATCGAGAACCCAAAACTGGAGGACACTGCAGGGGACACCGGGCACAGCAGCCTTGAGGCCCCCCGCAGCCCTGACACCCTGGCCC
CGGTGGCTTCTGAGCGGCTGCCCCCACAGCAGTCAGGGGGGCCAGAGGTTGAGACAAAACGTAAAGACAGTATTCTTCCCGAGCGCATCG
GGGAGCGGCCCAAAATTACCCTGCTCCAGTCTTCCAAAGACAGACTGCGGCGAAGGCTAAAGGAAAAGGTACCGGATGAAGTGGCCGTGG
AGACGACCACTCCCCAGCAGAACAAGATGGACAAGCTGATCGAGATCCTGAACAGCATGCGGAACAACAGCAGCGACGTGGACACCAAGC
TCACCACCTTCATGGAGGAGGCCCAGAACTCCACCAACTCCGAGGAGATGCTGGGCGAGATCGTGCGCACAATCTACCAGAAGGCTGTGT
CCGACCGCAGCTTCGCCTTCACCGCTGCCAAGCTCTGCGACAAGATGGCGCTCTTTATGGTGGAGGGGACCAAGTTCCGGAGCCTGCTCC
TCAACATGCTGCAGGTGCCAGAGTTTGTAGCCTATTGGAGGAAAACACACCAAGATCACCTCTGCAGCCTGCACAGCCGGGCCTTTGGAC
TCCTGGATGCTAGAGTGACCTGGGCGCTGAGGAGGGCCCCCGAGCCAGTACCAGGAAAGGATAGACTCCTGCTTGCAGCATTCCCAGCAG
AGGCATCGCCTGTGGACACCGCGTCTGTGTCTGTATATGGCAGAGCTCCCAGATATATGCACAAGGGAGTGAAAAAATGTGTTTGCACCC
CAGTCTCTAAAAATTCAACAGCCTGGTTACTTCTGGGTGGTATATCGTAGGTGGCTTTAATACGTGTTATTTGCTCATCTGTATTTCTTA
CTCTTTGCACAATTAAACCATGTTCCTTTTACTTATGTACATTTTTAATAAAAGAAAGTTGTTAATGACTCA

>20229_20229_7_CTIF-C5orf56_CTIF_chr18_46288060_ENST00000382998_C5orf56_chr5_131785342_ENST00000378953_length(amino acids)=560AA_BP=457
MENSSAASASSEAGSSRSQEIEELERFIDSYVLEYQVQGLLADKTEGDGESERTQSHISQWTADCSEPLDSSCSFSRGRAPPQQNGSKDN
SLDMLGTDIWAANTFDSFSGATWDLQPEKLDFTQFHRKVRHTPKQPLPHIDREGCGKGKLEDGDGINLNDIEKVLPAWQGYHPMPHEVEI
AHTKKLFRRRRNDRRRQQRPPGGNKPQQHGDHQPGSAKHNRDHQKSYQGGSAPHPSGRPTHHGYSQNRRWHHGNMKHPPGDKGEAGAHRN
AKETMTIENPKLEDTAGDTGHSSLEAPRSPDTLAPVASERLPPQQSGGPEVETKRKDSILPERIGERPKITLLQSSKDRLRRRLKEKVPD
EVAVETTTPQQNKMDKLIEILNSMRNNSSDVDTKLTTFMEEAQNSTNSEEMLGEIVRTIYQKAVSDRSFAFTAAKLCDKMALFMVEGTKF
RSLLLNMLQVPEFVAYWRKTHQDHLCSLHSRAFGLLDARVTWALRRAPEPVPGKDRLLLAAFPAEASPVDTASVSVYGRAPRYMHKGVKK
CVCTPVSKNSTAWLLLGGIS

--------------------------------------------------------------
>20229_20229_8_CTIF-C5orf56_CTIF_chr18_46288060_ENST00000382998_C5orf56_chr5_131785342_ENST00000407797_length(transcript)=2543nt_BP=1634nt
CTGTGCGCTGGGGCGCCCGATCCCCTCCGCAGCTGGGACGCTCCGAACTCGAGGCAGGAGTCGGCTCTCCGGAGCCTCGTCCCTCCCTTC
CCCTTCCCTGCCCCCTTCCCCCACCCCCGACTCGGGCTTGGCGCGGCGGCCAGAGGAACCCCGAGCCCGCATTTGCTGCATCGAGCAGTT
GGTTTAGTATCAGCCAAACTTGCAGCTGTTCAGACCGCGCTCCGCCGAGTCCCGGCCCAGGCCCCTGAGCTGGAGGGATGGAAAACTCCT
CTGCAGCATCAGCCTCCTCGGAGGCAGGGAGCAGCCGCTCCCAGGAGATCGAGGAGCTGGAGCGCTTCATCGACAGCTACGTGCTGGAGT
ACCAGGTGCAGGGGCTGCTGGCTGACAAGACGGAGGGTGATGGCGAGAGCGAGAGGACCCAGTCCCACATCTCCCAGTGGACAGCGGACT
GCAGCGAACCGCTGGACAGCAGCTGTTCCTTCTCCCGAGGGCGAGCCCCCCCACAGCAGAATGGCAGCAAAGACAACTCTCTGGACATGC
TGGGCACGGACATCTGGGCGGCCAACACCTTCGATTCCTTCAGTGGTGCCACCTGGGACCTGCAGCCGGAAAAGCTGGACTTCACCCAGT
TCCACCGCAAAGTCCGACACACGCCCAAGCAGCCCCTGCCACACATCGACCGCGAAGGGTGTGGCAAAGGGAAGCTGGAAGATGGGGATG
GCATCAACCTGAATGACATCGAGAAGGTCCTTCCAGCCTGGCAGGGCTACCACCCGATGCCCCATGAAGTGGAGATCGCACACACCAAGA
AGCTGTTCCGCAGGAGGAGAAATGATCGAAGGCGGCAGCAGAGACCTCCGGGGGGCAACAAGCCCCAACAGCATGGTGACCACCAGCCAG
GCAGTGCCAAACACAACAGGGACCACCAGAAATCCTACCAGGGGGGCTCAGCACCCCACCCCTCAGGGAGGCCCACTCACCATGGCTACA
GCCAGAACCGGCGCTGGCACCATGGCAACATGAAGCACCCACCAGGCGACAAGGGGGAGGCAGGCGCACACCGCAATGCCAAAGAGACCA
TGACCATCGAGAACCCAAAACTGGAGGACACTGCAGGGGACACCGGGCACAGCAGCCTTGAGGCCCCCCGCAGCCCTGACACCCTGGCCC
CGGTGGCTTCTGAGCGGCTGCCCCCACAGCAGTCAGGGGGGCCAGAGGTTGAGACAAAACGTAAAGACAGTATTCTTCCCGAGCGCATCG
GGGAGCGGCCCAAAATTACCCTGCTCCAGTCTTCCAAAGACAGACTGCGGCGAAGGCTAAAGGAAAAGGTACCGGATGAAGTGGCCGTGG
AGACGACCACTCCCCAGCAGAACAAGATGGACAAGCTGATCGAGATCCTGAACAGCATGCGGAACAACAGCAGCGACGTGGACACCAAGC
TCACCACCTTCATGGAGGAGGCCCAGAACTCCACCAACTCCGAGGAGATGCTGGGCGAGATCGTGCGCACAATCTACCAGAAGGCTGTGT
CCGACCGCAGCTTCGCCTTCACCGCTGCCAAGCTCTGCGACAAGATGGCGCTCTTTATGGTGGAGGGGACCAAGTTCCGGAGCCTGCTCC
TCAACATGCTGCAGGTGCCAGAGTTTGTAGCCTATTGGAGGAAAACACACCAAGCCCCGAACAGCACAGTGAATGGATAGGGCAGCAGAT
GAGCTCTGCCCCACGCCGGCCCTGTTTCAGAACAGCACTCCAGAGTGCCGCACTGCTTGCTGAACCACAGCTGTTACTGCAGATTGAGGA
GCCTCAGAGGGAACAGAAGATAAAGATCATTATGGAATTTAGGATTGCAGGACATTCTTTGACATTTCATAACAGCCAGGGGAGATCAAC
TGTGGTCAGGGGACAGGGGCAGGAAGAAACCATGGCCAAGGCCTGTCTGGCAGGACTTGAAGGGGCAGAGGGACCCTTGCAAATGACCCT
GCCTGGAACCCACCCCCAGTTGGCCCCTGTATAGCACTGATCCAGCTGGGGCTTTTATCCCAGGATACCCTCTTCAGGGATGCCTGTATT
TGTTGATTATCTGCCATATGCCTGGTCACTGCAGAATACAAGGAAGAAAATAGCCTTCAGCAGAAGCTGAGACAGGAGCCTAGAGGATGG
ACAGTAAGGAGTCGAAGGCTCAGGATGAGGCTTTCCTGACTTTCTCCCCTAGAGGACTGATGTTCTCTACTGGTACAGACCTTGTTTTAT
TCATCCTTATGTCCCTAACCTGGAATGGGCCCAGGGTGACAGTTATAATAAGTGTTTGTCAAGTGAGCAAGTGTGTGGAGTGTGCATTGT
AGAGAGTAAGGTCTCTACAGGATCCTGCTGGAGAGGCAGCCCACTGGGCTCACCACTTCTCCAGAGGAGGGACTGGTCCCTTGCCAGACA
GCCCTGCCAGCTGGAGCAGGCTTCCTCAGGGGTGCCTGGAGCTGTTGACCATGGCTGTTGCCCTCTGGCCCCTCTTGGGAAGAGCAACCT
GTCAGGTGTTAAAGACGGTCTTC

>20229_20229_8_CTIF-C5orf56_CTIF_chr18_46288060_ENST00000382998_C5orf56_chr5_131785342_ENST00000407797_length(amino acids)=480AA_BP=457
MENSSAASASSEAGSSRSQEIEELERFIDSYVLEYQVQGLLADKTEGDGESERTQSHISQWTADCSEPLDSSCSFSRGRAPPQQNGSKDN
SLDMLGTDIWAANTFDSFSGATWDLQPEKLDFTQFHRKVRHTPKQPLPHIDREGCGKGKLEDGDGINLNDIEKVLPAWQGYHPMPHEVEI
AHTKKLFRRRRNDRRRQQRPPGGNKPQQHGDHQPGSAKHNRDHQKSYQGGSAPHPSGRPTHHGYSQNRRWHHGNMKHPPGDKGEAGAHRN
AKETMTIENPKLEDTAGDTGHSSLEAPRSPDTLAPVASERLPPQQSGGPEVETKRKDSILPERIGERPKITLLQSSKDRLRRRLKEKVPD
EVAVETTTPQQNKMDKLIEILNSMRNNSSDVDTKLTTFMEEAQNSTNSEEMLGEIVRTIYQKAVSDRSFAFTAAKLCDKMALFMVEGTKF
RSLLLNMLQVPEFVAYWRKTHQAPNSTVNG

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Fusion Gene PPI Analysis for CTIF-C5orf56


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
HgeneCTIFchr18:46288060chr5:131785342ENST00000256413+9121_305457.0599.0NCBP1/CBP80
HgeneCTIFchr18:46288060chr5:131785342ENST00000382998+10131_305459.0601.0NCBP1/CBP80


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for CTIF-C5orf56


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for CTIF-C5orf56


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource