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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:CEP350-TOR1AIP1 (FusionGDB2 ID:HG9857TG26092)

Fusion Gene Summary for CEP350-TOR1AIP1

check button Fusion gene summary
Fusion gene informationFusion gene name: CEP350-TOR1AIP1
Fusion gene ID: hg9857tg26092
HgeneTgene
Gene symbol

CEP350

TOR1AIP1

Gene ID

9857

26092

Gene namecentrosomal protein 350torsin 1A interacting protein 1
SynonymsCAP350|GM133LAP1|LAP1B|LAP1C|LGMD2Y
Cytomap('CEP350')('TOR1AIP1')

1q25.2

1q25.2

Type of geneprotein-codingprotein-coding
Descriptioncentrosome-associated protein 350centrosomal protein 350kDatorsin-1A-interacting protein 1lamin-associated protein 1Blamina-associated polypeptide 1Btorsin A interacting protein 1
Modification date2020031320200329
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000367607, ENST00000490141, 
Fusion gene scores* DoF score11 X 10 X 8=8806 X 5 X 4=120
# samples 137
** MAII scorelog2(13/880*10)=-2.75899190049621
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(7/120*10)=-0.777607578663552
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: CEP350 [Title/Abstract] AND TOR1AIP1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCEP350(179981210)-TOR1AIP1(179869261), # samples:3
Anticipated loss of major functional domain due to fusion event.CEP350-TOR1AIP1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
CEP350-TOR1AIP1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
CEP350-TOR1AIP1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
CEP350-TOR1AIP1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneTOR1AIP1

GO:0032781

positive regulation of ATPase activity

23569223


check buttonFusion gene breakpoints across CEP350 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across TOR1AIP1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BLCATCGA-E7-A85H-01ACEP350chr1

179981210

-TOR1AIP1chr1

179869261

+
ChimerDB4BLCATCGA-E7-A85H-01ACEP350chr1

179981210

+TOR1AIP1chr1

179869261

+
ChimerDB4BLCATCGA-UY-A9PE-01ACEP350chr1

179966310

-TOR1AIP1chr1

179869261

+
ChimerDB4BLCATCGA-UY-A9PE-01ACEP350chr1

179966310

+TOR1AIP1chr1

179869261

+


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Fusion Gene ORF analysis for CEP350-TOR1AIP1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000367607ENST00000474875CEP350chr1

179981210

+TOR1AIP1chr1

179869261

+
5CDS-3UTRENST00000367607ENST00000474875CEP350chr1

179966310

+TOR1AIP1chr1

179869261

+
In-frameENST00000367607ENST00000271583CEP350chr1

179981210

+TOR1AIP1chr1

179869261

+
In-frameENST00000367607ENST00000271583CEP350chr1

179966310

+TOR1AIP1chr1

179869261

+
In-frameENST00000367607ENST00000435319CEP350chr1

179981210

+TOR1AIP1chr1

179869261

+
In-frameENST00000367607ENST00000435319CEP350chr1

179966310

+TOR1AIP1chr1

179869261

+
In-frameENST00000367607ENST00000528443CEP350chr1

179981210

+TOR1AIP1chr1

179869261

+
In-frameENST00000367607ENST00000528443CEP350chr1

179966310

+TOR1AIP1chr1

179869261

+
In-frameENST00000367607ENST00000606911CEP350chr1

179981210

+TOR1AIP1chr1

179869261

+
In-frameENST00000367607ENST00000606911CEP350chr1

179966310

+TOR1AIP1chr1

179869261

+
intron-3CDSENST00000490141ENST00000271583CEP350chr1

179981210

+TOR1AIP1chr1

179869261

+
intron-3CDSENST00000490141ENST00000271583CEP350chr1

179966310

+TOR1AIP1chr1

179869261

+
intron-3CDSENST00000490141ENST00000435319CEP350chr1

179981210

+TOR1AIP1chr1

179869261

+
intron-3CDSENST00000490141ENST00000435319CEP350chr1

179966310

+TOR1AIP1chr1

179869261

+
intron-3CDSENST00000490141ENST00000528443CEP350chr1

179981210

+TOR1AIP1chr1

179869261

+
intron-3CDSENST00000490141ENST00000528443CEP350chr1

179966310

+TOR1AIP1chr1

179869261

+
intron-3CDSENST00000490141ENST00000606911CEP350chr1

179981210

+TOR1AIP1chr1

179869261

+
intron-3CDSENST00000490141ENST00000606911CEP350chr1

179966310

+TOR1AIP1chr1

179869261

+
intron-3UTRENST00000490141ENST00000474875CEP350chr1

179981210

+TOR1AIP1chr1

179869261

+
intron-3UTRENST00000490141ENST00000474875CEP350chr1

179966310

+TOR1AIP1chr1

179869261

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000367607CEP350chr1179981210+ENST00000528443TOR1AIP1chr1179869261+442218114182952844
ENST00000367607CEP350chr1179981210+ENST00000271583TOR1AIP1chr1179869261+403618114182997859
ENST00000367607CEP350chr1179981210+ENST00000606911TOR1AIP1chr1179869261+971418114182952844
ENST00000367607CEP350chr1179981210+ENST00000435319TOR1AIP1chr1179869261+479118114182952844

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000367607ENST00000528443CEP350chr1179981210+TOR1AIP1chr1179869261+0.0005859210.9994141
ENST00000367607ENST00000271583CEP350chr1179981210+TOR1AIP1chr1179869261+0.0007157860.9992842
ENST00000367607ENST00000606911CEP350chr1179981210+TOR1AIP1chr1179869261+0.0002698640.99973017
ENST00000367607ENST00000435319CEP350chr1179981210+TOR1AIP1chr1179869261+0.0003828340.9996171

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Fusion Genomic Features for CEP350-TOR1AIP1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
CEP350chr1179966310+TOR1AIP1chr1179869260+0.0028152930.9971847
CEP350chr1179981210+TOR1AIP1chr1179869260+1.27E-081
CEP350chr1179966310+TOR1AIP1chr1179869260+0.0028152930.9971847
CEP350chr1179981210+TOR1AIP1chr1179869260+1.27E-081

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for CEP350-TOR1AIP1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr1:179981210/chr1:179869261)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneTOR1AIP1chr1:179966310chr1:179869261ENST00000435319210359_43582463.0Coiled coilOntology_term=ECO:0000255
TgeneTOR1AIP1chr1:179981210chr1:179869261ENST00000435319210359_43582463.0Coiled coilOntology_term=ECO:0000255
TgeneTOR1AIP1chr1:179966310chr1:179869261ENST00000435319210339_35582463.0TransmembraneHelical
TgeneTOR1AIP1chr1:179981210chr1:179869261ENST00000435319210339_35582463.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCEP350chr1:179966310chr1:179869261ENST00000367607+6381369_14113393118.0Coiled coilOntology_term=ECO:0000255
HgeneCEP350chr1:179966310chr1:179869261ENST00000367607+6381707_18003393118.0Coiled coilOntology_term=ECO:0000255
HgeneCEP350chr1:179966310chr1:179869261ENST00000367607+6381856_18993393118.0Coiled coilOntology_term=ECO:0000255
HgeneCEP350chr1:179966310chr1:179869261ENST00000367607+6382051_21103393118.0Coiled coilOntology_term=ECO:0000255
HgeneCEP350chr1:179966310chr1:179869261ENST00000367607+6382719_27523393118.0Coiled coilOntology_term=ECO:0000255
HgeneCEP350chr1:179966310chr1:179869261ENST00000367607+638598_6453393118.0Coiled coilOntology_term=ECO:0000255
HgeneCEP350chr1:179981210chr1:179869261ENST00000367607+9381369_14114643118.0Coiled coilOntology_term=ECO:0000255
HgeneCEP350chr1:179981210chr1:179869261ENST00000367607+9381707_18004643118.0Coiled coilOntology_term=ECO:0000255
HgeneCEP350chr1:179981210chr1:179869261ENST00000367607+9381856_18994643118.0Coiled coilOntology_term=ECO:0000255
HgeneCEP350chr1:179981210chr1:179869261ENST00000367607+9382051_21104643118.0Coiled coilOntology_term=ECO:0000255
HgeneCEP350chr1:179981210chr1:179869261ENST00000367607+9382719_27524643118.0Coiled coilOntology_term=ECO:0000255
HgeneCEP350chr1:179981210chr1:179869261ENST00000367607+938598_6454643118.0Coiled coilOntology_term=ECO:0000255
HgeneCEP350chr1:179966310chr1:179869261ENST00000367607+6381112_12813393118.0Compositional biasNote=Ser-rich
HgeneCEP350chr1:179966310chr1:179869261ENST00000367607+6381502_15563393118.0Compositional biasNote=Ser-rich
HgeneCEP350chr1:179981210chr1:179869261ENST00000367607+9381112_12814643118.0Compositional biasNote=Ser-rich
HgeneCEP350chr1:179981210chr1:179869261ENST00000367607+9381502_15564643118.0Compositional biasNote=Ser-rich
HgeneCEP350chr1:179966310chr1:179869261ENST00000367607+6382517_25593393118.0DomainCAP-Gly
HgeneCEP350chr1:179981210chr1:179869261ENST00000367607+9382517_25594643118.0DomainCAP-Gly
TgeneTOR1AIP1chr1:179966310chr1:179869261ENST000004353192101_33882463.0Topological domainNuclear
TgeneTOR1AIP1chr1:179981210chr1:179869261ENST000004353192101_33882463.0Topological domainNuclear


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Fusion Gene Sequence for CEP350-TOR1AIP1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>15859_15859_1_CEP350-TOR1AIP1_CEP350_chr1_179981210_ENST00000367607_TOR1AIP1_chr1_179869261_ENST00000271583_length(transcript)=4036nt_BP=1811nt
GCCCGACTGCTCCCGCCCTGCCTCGCGCCGCCGCCACAGCCGCTGCCGCTGGCGCCGCTCCTCCTCCGTGTCAGTTGTTGGGCTGTAATG
GCGACTGGGCCGCCCCTGACGAAGTGACTCCCGGGCCGGGGAGCGGGGCCAGACCTGCGCCAGAGAGAACTGCAGGGAGCCGCAGCTCGG
GGGGTGGCTTGCCCTGAGGGAGGGGAGGCAGCCTTTCCGCCTTGTCTTCCTTCCCAGCGGACCGGCGGATCCCCGGAGCCGGTGCGAGGA
GGGCACCCGGTGCGTCCCCGGAGCGGGGAGGCCAGGCCGGGCAGCCCTGGGGCCGGTCGGGGCGGCGTCACTGCACCCTCCGCCAGGCTC
CGCGGGATGCACCGTGGTAGCCGAGGGCGGAGGCGACACTCTCAGGTAAATTGGCAGGATGAGGAGCAGCAAATCAAAAGAGGTGCCTTT
ACCAAATCCAAGGAACTCTCAAAGCAAGGATACTGTTCAAGCAGATATAACCACATCGTGGGATGCACTTTCTCAAACCAAGGCTGCTCT
GAGACACATTGAAAATAAATTAGAAGTAGCCCCTACAAGTACAGCTGTGTGTGATTCTGTCATGGATACCAAGAAGTCTTCTACAAGTGC
TACTCGAAAAATAAGTAGAAAAGATGGTAGATACCTGGATGATTCTTGGGTTAATGCTCCAATCTCCAAATCCACTAAATCACGAAAAGA
GAAATCTCGTAGTCCTCTCAGGGCCACCACCCTGGAGAGTAATGTGAAGAAAAATAATCGTGTGGAATTTCGTGAACCTTTGGTTTCTTA
TAGGGAAATCCATGGTGCACCTTCCAATTTCAGTTCCAGCCATCTGGAATCAAAGCACGTATACTGTGTAGATGTTAATGAAGAAAAGAC
TGAGAGCGGTAACTGGATGATAGGCAGTCGAGAAGAACGGAATATACGGAGCTGTGATTTTGAGAGCTCCCAATCATCTGTCATCAATGA
TACAGTTGTTAGGTTTTTAAATGATCGACCAGCAATTGATGCATTGCAAAATTCTGAATGTTTGATTAGGATGGGAGCTTCTATGAGAAC
TGAGGAAGAAATGCCTAACAGAACAAAAGGAAGTGAGAATAATTTGAAGCTTTCTGTGAATAACATGGCCCATGATACTGATCCAAAAGC
GTTACGACTAACTGACTCTTCTCCATCCTCTACTAGTACTTCTAATTCCCAAAGATTAGATATTCTAAAGCGGCGACAACATGATGTCAA
ACTGGAAAAACTTAAGGAACGGATTAGAAAACAGTGGGAACACTCAGAAGAAACAAATGGCCGGGGCCAGAAGCTGGGTCATATTGACCA
TCCAGTAATGGTTGTTAATGTTGATAACTCAGTAACAGCAAAAGTCAGAAAAGTGGCAACAGCACCACCTGCTCCAGCATATAAAGGTTT
CAACCCTTCAGAGACCAAGATTCGAACACCTGATGGGAAAGTGTGGCAGGAGGCTGAGTTTCAAAACATGAGTAGAGAACTGTATCGAGA
TTTAGCACTTCACTTTGCAGATGATATTTCTATAAAGGAGAAACCTGCTGAAAAAAGTAAAGAGAAGAAAGTAGTCAAGCCAGTACGAAA
AGTCCAAAAAGTAGCACAGTTATCAAGTACAGAATGCAGAACAGGTAGTAGTCATCTTATAAGTACATCTTCTTGGCGAGATGGACAAAA
ATTAGTAAAGAAGATTCTGGGACCTGCTCCCAGAATGGAGCCAAAAGAGCAAAGAACAGCATCAAGTGACAGAGGTGGAAGAGAAAGAAC
TGCTAAATCTGAAGCCACCAGTGTCCAACAGAAGGTCAATTTCTCTGAAGAAGGAGAAACTGAAGAAGATGATCAAGACAGCTCTCACAG
CAGTGTCACTACTGTTAAGGCCAGATCCAGGGATTCTGATGAATCTGGAGATAAAACCACCAGATCATCTAGTCAATATATAGAATCATT
TTGGCAGTCATCACAAAGTCAAAACTTCACAGCTCATGATAAGCAACCTTCAGTGCTAAGCTCAGGATATCAAAAAACTCCCCAGGAATG
GGCCCCACAAACTGCAAGAATAAGGACCAGGATGCAAACATCTTCACCAGGCAAGAGTTCAATATATGGCAGTTTTTCAGATGATGACAG
CATTCTGAAATCAGAGCTTGGAAACCAGTCACCATCAACCTCCAGCCGACAAGTGACTGGACAACCCCAAAATGCATCTTTTGTCAAGAG
GAACCGGTGGTGGCTACTTCCTCTGATAGCTGCTCTTGCCTCTGGGAGTTTTTGGTTCTTTAGTACTCCTGAGGTAGAAACCACTGCTGT
TCAAGAGTTCCAGAACCAGATGAATCAACTTAAGAATAAGTACCAAGGTCAAGATGAGAAGCTGTGGAAAAGGAGCCAAACATTCCTGGA
AAAACATCTTAATAGCTCCCATCCTCGGTCTCAGCCTGCTATCTTACTGCTCACTGCTGCCCGAGATGCTGAAGAAGCACTTAGGTGTCT
GAGTGAACAAATTGCTGATGCCTATTCTTCTTTTCGTAGTGTCCGTGCCATCCGGATTGATGGGACAGATAAAGCTACTCAAGACAGTGA
TACTGTCAAACTAGAGGTAGACCAAGAACTGAGCAATGGATTTAAGAATGGCCAGAATGCAGCTGTGGTACACCGCTTTGAGTCATTTCC
CGCAGGCTCTACTTTGATCTTCTACAAATATTGTGACCATGAAAACGCGGCCTTCAAAGATGTAGCCTTAGTCCTGACTGTCTTATTGGA
GGAAGAGACACTTGGAACAAGTCTAGGCCTAAAGGAAGTTGAAGAAAAAGTAAGAGATTTTCTTAAAGTCAAGTTCACCAATTCTAACAC
ACCCAACTCCTACAATCATATGGACCCAGACAAACTGAATGGCCTCTGGAGCCGTATTTCTCACTTAGTTCTGCCTGTGCAACCTGAAAA
TGCCCTGAAAAGGGGCATCTGCTTATAAGAAGTGAGAGAGAAGAAAAATCATGTCCCAAGTTCTGAGAATTGTTCACACTTTCTAACCAG
AGACAGAATTCAGAGCTCTTTTTGAAAGAACTAGTTTCTTTTTAAAGAAGTTAAGTGCTTACATAAACATGGAACATATAAATCATTCAT
TCAACCTAATTATCTGTGATATGAGAGAATCATTTCAGTTTCCATTGAGAGCTCTGTTAAAGGTATCTTAGGAGTGCAGATTATATGCAG
TTCCTTAGAGAATCTGTTTTGATTCTGGGCTGAGTTATTACAGTTATGGTATGACCAGTGAGAGGGATTTGTGTCCTTTCTTATGAACCT
TCCTGATTTTTTAACTTAGATTTCTCACTAAGTTTCCTGAGTTATTAGTAAGATTGCTCCCTAAATGTAACCAGGGATTTTCCCATTATG
TTCCCTTTTATACCATTTAGGTGTGAGTTCCTTAGCTTCTGCCTATAGGAACATAAGTAATGAAAGGTCATCTAGGTGTGTGTTTGGAAT
TTTTTTCTTTTGTTTTTTGGAAAATGGAAAGAACAAGGCAAGGAAGGAAAATTAATGGGGAAGCTGAAGGGAGGAAATGTTACAGTAATC
CACTGAGATGTAGTTTAGTCAAACATAGGTATATGAACTGTTAATCTTGGTGGATTCCGTTGGGATTTGTTTTTTACATCTCCTTTTTCC
TTCCTTGAAGAAAAATTCTTGGCTGTCCCAAGGATTCTTCATGTATATTGCAAAATTTAATATATTTGTTCACTTGAGTCTTAAGAGTAG
GTCAGGCCAAGGCAGGTGGATCACCTGAGGTCAGAAGTTCAAGACCAGCCTGGCCAACATGGTGAAACCCCGTCTCTACTAAAAATACAA
AAATTAGCTGGGCGTGGTGGTGCATGCCTGAAATCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATTGCTTGAACCCGGGAGGCGGAGGT

>15859_15859_1_CEP350-TOR1AIP1_CEP350_chr1_179981210_ENST00000367607_TOR1AIP1_chr1_179869261_ENST00000271583_length(amino acids)=859AA_BP=678
MRSSKSKEVPLPNPRNSQSKDTVQADITTSWDALSQTKAALRHIENKLEVAPTSTAVCDSVMDTKKSSTSATRKISRKDGRYLDDSWVNA
PISKSTKSRKEKSRSPLRATTLESNVKKNNRVEFREPLVSYREIHGAPSNFSSSHLESKHVYCVDVNEEKTESGNWMIGSREERNIRSCD
FESSQSSVINDTVVRFLNDRPAIDALQNSECLIRMGASMRTEEEMPNRTKGSENNLKLSVNNMAHDTDPKALRLTDSSPSSTSTSNSQRL
DILKRRQHDVKLEKLKERIRKQWEHSEETNGRGQKLGHIDHPVMVVNVDNSVTAKVRKVATAPPAPAYKGFNPSETKIRTPDGKVWQEAE
FQNMSRELYRDLALHFADDISIKEKPAEKSKEKKVVKPVRKVQKVAQLSSTECRTGSSHLISTSSWRDGQKLVKKILGPAPRMEPKEQRT
ASSDRGGRERTAKSEATSVQQKVNFSEEGETEEDDQDSSHSSVTTVKARSRDSDESGDKTTRSSSQYIESFWQSSQSQNFTAHDKQPSVL
SSGYQKTPQEWAPQTARIRTRMQTSSPGKSSIYGSFSDDDSILKSELGNQSPSTSSRQVTGQPQNASFVKRNRWWLLPLIAALASGSFWF
FSTPEVETTAVQEFQNQMNQLKNKYQGQDEKLWKRSQTFLEKHLNSSHPRSQPAILLLTAARDAEEALRCLSEQIADAYSSFRSVRAIRI
DGTDKATQDSDTVKLEVDQELSNGFKNGQNAAVVHRFESFPAGSTLIFYKYCDHENAAFKDVALVLTVLLEEETLGTSLGLKEVEEKVRD

--------------------------------------------------------------
>15859_15859_2_CEP350-TOR1AIP1_CEP350_chr1_179981210_ENST00000367607_TOR1AIP1_chr1_179869261_ENST00000435319_length(transcript)=4791nt_BP=1811nt
GCCCGACTGCTCCCGCCCTGCCTCGCGCCGCCGCCACAGCCGCTGCCGCTGGCGCCGCTCCTCCTCCGTGTCAGTTGTTGGGCTGTAATG
GCGACTGGGCCGCCCCTGACGAAGTGACTCCCGGGCCGGGGAGCGGGGCCAGACCTGCGCCAGAGAGAACTGCAGGGAGCCGCAGCTCGG
GGGGTGGCTTGCCCTGAGGGAGGGGAGGCAGCCTTTCCGCCTTGTCTTCCTTCCCAGCGGACCGGCGGATCCCCGGAGCCGGTGCGAGGA
GGGCACCCGGTGCGTCCCCGGAGCGGGGAGGCCAGGCCGGGCAGCCCTGGGGCCGGTCGGGGCGGCGTCACTGCACCCTCCGCCAGGCTC
CGCGGGATGCACCGTGGTAGCCGAGGGCGGAGGCGACACTCTCAGGTAAATTGGCAGGATGAGGAGCAGCAAATCAAAAGAGGTGCCTTT
ACCAAATCCAAGGAACTCTCAAAGCAAGGATACTGTTCAAGCAGATATAACCACATCGTGGGATGCACTTTCTCAAACCAAGGCTGCTCT
GAGACACATTGAAAATAAATTAGAAGTAGCCCCTACAAGTACAGCTGTGTGTGATTCTGTCATGGATACCAAGAAGTCTTCTACAAGTGC
TACTCGAAAAATAAGTAGAAAAGATGGTAGATACCTGGATGATTCTTGGGTTAATGCTCCAATCTCCAAATCCACTAAATCACGAAAAGA
GAAATCTCGTAGTCCTCTCAGGGCCACCACCCTGGAGAGTAATGTGAAGAAAAATAATCGTGTGGAATTTCGTGAACCTTTGGTTTCTTA
TAGGGAAATCCATGGTGCACCTTCCAATTTCAGTTCCAGCCATCTGGAATCAAAGCACGTATACTGTGTAGATGTTAATGAAGAAAAGAC
TGAGAGCGGTAACTGGATGATAGGCAGTCGAGAAGAACGGAATATACGGAGCTGTGATTTTGAGAGCTCCCAATCATCTGTCATCAATGA
TACAGTTGTTAGGTTTTTAAATGATCGACCAGCAATTGATGCATTGCAAAATTCTGAATGTTTGATTAGGATGGGAGCTTCTATGAGAAC
TGAGGAAGAAATGCCTAACAGAACAAAAGGAAGTGAGAATAATTTGAAGCTTTCTGTGAATAACATGGCCCATGATACTGATCCAAAAGC
GTTACGACTAACTGACTCTTCTCCATCCTCTACTAGTACTTCTAATTCCCAAAGATTAGATATTCTAAAGCGGCGACAACATGATGTCAA
ACTGGAAAAACTTAAGGAACGGATTAGAAAACAGTGGGAACACTCAGAAGAAACAAATGGCCGGGGCCAGAAGCTGGGTCATATTGACCA
TCCAGTAATGGTTGTTAATGTTGATAACTCAGTAACAGCAAAAGTCAGAAAAGTGGCAACAGCACCACCTGCTCCAGCATATAAAGGTTT
CAACCCTTCAGAGACCAAGATTCGAACACCTGATGGGAAAGTGTGGCAGGAGGCTGAGTTTCAAAACATGAGTAGAGAACTGTATCGAGA
TTTAGCACTTCACTTTGCAGATGATATTTCTATAAAGGAGAAACCTGCTGAAAAAAGTAAAGAGAAGAAAGTAGTCAAGCCAGTACGAAA
AGTCCAAAAAGTAGCACAGTTATCAAGTACAGAATGCAGAACAGGTAGTAGTCATCTTATAAGTACATCTTCTTGGCGAGATGGACAAAA
ATTAGTAAAGAAGATTCTGGGACCTGCTCCCAGAATGGAGCCAAAAGAGCAAAGAACAGCATCAAGTGACAGAGGTGGAAGAGAAAGAAC
TGCTAAATCTGAAGCCACCAGTGTCCAACAGAAGGTCAATTTCTCTGAAGAAGGAGAAACTGAAGAAGATGATCAAGACAGCTCTCACAG
CAGTGTCACTACTGTTAAGGCCAGATCCAGGGATTCTGATGAATCTGGAGATAAAACCACCAGATCATCTAGTCAATATATAGAATCATT
TTGGCAGTCATCACAAAGTCAAAACTTCACAGCTCATGATAAGCAACCTTCAGTGCTAAGCTCAGGATATCAAAAAACTCCCCAGGAATG
GGCCCCACAAACTGCAAGAATAAGGACCAGGATGCAAAATGACAGCATTCTGAAATCAGAGCTTGGAAACCAGTCACCATCAACCTCCAG
CCGACAAGTGACTGGACAACCCCAAAATGCATCTTTTGTCAAGAGGAACCGGTGGTGGCTACTTCCTCTGATAGCTGCTCTTGCCTCTGG
GAGTTTTTGGTTCTTTAGTACTCCTGAGGTAGAAACCACTGCTGTTCAAGAGTTCCAGAACCAGATGAATCAACTTAAGAATAAGTACCA
AGGTCAAGATGAGAAGCTGTGGAAAAGGAGCCAAACATTCCTGGAAAAACATCTTAATAGCTCCCATCCTCGGTCTCAGCCTGCTATCTT
ACTGCTCACTGCTGCCCGAGATGCTGAAGAAGCACTTAGGTGTCTGAGTGAACAAATTGCTGATGCCTATTCTTCTTTTCGTAGTGTCCG
TGCCATCCGGATTGATGGGACAGATAAAGCTACTCAAGACAGTGATACTGTCAAACTAGAGGTAGACCAAGAACTGAGCAATGGATTTAA
GAATGGCCAGAATGCAGCTGTGGTACACCGCTTTGAGTCATTTCCCGCAGGCTCTACTTTGATCTTCTACAAATATTGTGACCATGAAAA
CGCGGCCTTCAAAGATGTAGCCTTAGTCCTGACTGTCTTATTGGAGGAAGAGACACTTGGAACAAGTCTAGGCCTAAAGGAAGTTGAAGA
AAAAGTAAGAGATTTTCTTAAAGTCAAGTTCACCAATTCTAACACACCCAACTCCTACAATCATATGGACCCAGACAAACTGAATGGCCT
CTGGAGCCGTATTTCTCACTTAGTTCTGCCTGTGCAACCTGAAAATGCCCTGAAAAGGGGCATCTGCTTATAAGAAGTGAGAGAGAAGAA
AAATCATGTCCCAAGTTCTGAGAATTGTTCACACTTTCTAACCAGAGACAGAATTCAGAGCTCTTTTTGAAAGAACTAGTTTCTTTTTAA
AGAAGTTAAGTGCTTACATAAACATGGAACATATAAATCATTCATTCAACCTAATTATCTGTGATATGAGAGAATCATTTCAGTTTCCAT
TGAGAGCTCTGTTAAAGGTATCTTAGGAGTGCAGATTATATGCAGTTCCTTAGAGAATCTGTTTTGATTCTGGGCTGAGTTATTACAGTT
ATGGTATGACCAGTGAGAGGGATTTGTGTCCTTTCTTATGAACCTTCCTGATTTTTTAACTTAGATTTCTCACTAAGTTTCCTGAGTTAT
TAGTAAGATTGCTCCCTAAATGTAACCAGGGATTTTCCCATTATGTTCCCTTTTATACCATTTAGGTGTGAGTTCCTTAGCTTCTGCCTA
TAGGAACATAAGTAATGAAAGGTCATCTAGGTGTGTGTTTGGAATTTTTTTCTTTTGTTTTTTGGAAAATGGAAAGAACAAGGCAAGGAA
GGAAAATTAATGGGGAAGCTGAAGGGAGGAAATGTTACAGTAATCCACTGAGATGTAGTTTAGTCAAACATAGGTATATGAACTGTTAAT
CTTGGTGGATTCCGTTGGGATTTGTTTTTTACATCTCCTTTTTCCTTCCTTGAAGAAAAATTCTTGGCTGTCCCAAGGATTCTTCATGTA
TATTGCAAAATTTAATATATTTGTTCACTTGAGTCTTAAGAGTAGGTCAGGCCAAGGCAGGTGGATCACCTGAGGTCAGAAGTTCAAGAC
CAGCCTGGCCAACATGGTGAAACCCCGTCTCTACTAAAAATACAAAAATTAGCTGGGCGTGGTGGTGCATGCCTGAAATCCCAGCTACTT
GGGAGGCTGAGGCAGGAGAATTGCTTGAACCCGGGAGGCGGAGGTTGCAGTAAGCCGAGACCATGCTTATTGCCCTCCAGTCTGGGCAAC
AAAAATGAAACTCCGTCTCAAAAAAAAAAAAGTAGGTCAATTCGTAACAGTTTATTTTGGACACACCCTGAAGCTTTTGTTTTGAATTAA
GAAATGAGTTTCAGGAATTGACAAACCATTTGTTAACCAGCTGTCCTGGGCTATTGAAGAAGATTTCATTTTCCGCGCATCCACTTGTTG
CAGTCCAAGTCCTCTAGTGCAACGCCATAGCAAATATAAAGATTTACTATGCACGTGATACATTTTATGGAGTGCCTCAAGCCAAGATAG
TGAATTTATATGAAGGGTGTGAAATGTATTTCTTTACTACTATAGTAGTTTAGTTATAACTTTGCATCTATAATTGAGCTTTCTCATCTG
TCAAATGCTATGGTTTTCTTAAAATGTTACAATTCTAGATCTATCCACCTTGTTTTTTTATTGTCTACAAACCATTAAATGTAAATATTG
TTTTTAGAGTCAGTCATTGGCTTTGTCATTTACCCTTTGAGAGTTCCACAAGTGGTAGTAGAGTGGTTTAACGTCTTTCCTCTAGTACTA
CCAGTATTCATAAATGTATACCCCTTACTGTAATTTGTTCCTCTTAGAAGTCAGATCATCTGATTTATAGAGGATTATGAAAACCAGAGT
TTTTGAAAAGGCTTATTTTATACATACGTATTATATAGAGAAACAAATGTTTTTATTAAATGTTTCATTGACCCAAGTAATTTAAAAGTA
ATATGTTACCTATGTCTTTCAGGAAAAATAATTATAGCAGCTGATCTGTAAATGACTTTAAAAGCTATTTTAGTAATTTAAATAAATTTA

>15859_15859_2_CEP350-TOR1AIP1_CEP350_chr1_179981210_ENST00000367607_TOR1AIP1_chr1_179869261_ENST00000435319_length(amino acids)=844AA_BP=663
MRSSKSKEVPLPNPRNSQSKDTVQADITTSWDALSQTKAALRHIENKLEVAPTSTAVCDSVMDTKKSSTSATRKISRKDGRYLDDSWVNA
PISKSTKSRKEKSRSPLRATTLESNVKKNNRVEFREPLVSYREIHGAPSNFSSSHLESKHVYCVDVNEEKTESGNWMIGSREERNIRSCD
FESSQSSVINDTVVRFLNDRPAIDALQNSECLIRMGASMRTEEEMPNRTKGSENNLKLSVNNMAHDTDPKALRLTDSSPSSTSTSNSQRL
DILKRRQHDVKLEKLKERIRKQWEHSEETNGRGQKLGHIDHPVMVVNVDNSVTAKVRKVATAPPAPAYKGFNPSETKIRTPDGKVWQEAE
FQNMSRELYRDLALHFADDISIKEKPAEKSKEKKVVKPVRKVQKVAQLSSTECRTGSSHLISTSSWRDGQKLVKKILGPAPRMEPKEQRT
ASSDRGGRERTAKSEATSVQQKVNFSEEGETEEDDQDSSHSSVTTVKARSRDSDESGDKTTRSSSQYIESFWQSSQSQNFTAHDKQPSVL
SSGYQKTPQEWAPQTARIRTRMQNDSILKSELGNQSPSTSSRQVTGQPQNASFVKRNRWWLLPLIAALASGSFWFFSTPEVETTAVQEFQ
NQMNQLKNKYQGQDEKLWKRSQTFLEKHLNSSHPRSQPAILLLTAARDAEEALRCLSEQIADAYSSFRSVRAIRIDGTDKATQDSDTVKL
EVDQELSNGFKNGQNAAVVHRFESFPAGSTLIFYKYCDHENAAFKDVALVLTVLLEEETLGTSLGLKEVEEKVRDFLKVKFTNSNTPNSY

--------------------------------------------------------------
>15859_15859_3_CEP350-TOR1AIP1_CEP350_chr1_179981210_ENST00000367607_TOR1AIP1_chr1_179869261_ENST00000528443_length(transcript)=4422nt_BP=1811nt
GCCCGACTGCTCCCGCCCTGCCTCGCGCCGCCGCCACAGCCGCTGCCGCTGGCGCCGCTCCTCCTCCGTGTCAGTTGTTGGGCTGTAATG
GCGACTGGGCCGCCCCTGACGAAGTGACTCCCGGGCCGGGGAGCGGGGCCAGACCTGCGCCAGAGAGAACTGCAGGGAGCCGCAGCTCGG
GGGGTGGCTTGCCCTGAGGGAGGGGAGGCAGCCTTTCCGCCTTGTCTTCCTTCCCAGCGGACCGGCGGATCCCCGGAGCCGGTGCGAGGA
GGGCACCCGGTGCGTCCCCGGAGCGGGGAGGCCAGGCCGGGCAGCCCTGGGGCCGGTCGGGGCGGCGTCACTGCACCCTCCGCCAGGCTC
CGCGGGATGCACCGTGGTAGCCGAGGGCGGAGGCGACACTCTCAGGTAAATTGGCAGGATGAGGAGCAGCAAATCAAAAGAGGTGCCTTT
ACCAAATCCAAGGAACTCTCAAAGCAAGGATACTGTTCAAGCAGATATAACCACATCGTGGGATGCACTTTCTCAAACCAAGGCTGCTCT
GAGACACATTGAAAATAAATTAGAAGTAGCCCCTACAAGTACAGCTGTGTGTGATTCTGTCATGGATACCAAGAAGTCTTCTACAAGTGC
TACTCGAAAAATAAGTAGAAAAGATGGTAGATACCTGGATGATTCTTGGGTTAATGCTCCAATCTCCAAATCCACTAAATCACGAAAAGA
GAAATCTCGTAGTCCTCTCAGGGCCACCACCCTGGAGAGTAATGTGAAGAAAAATAATCGTGTGGAATTTCGTGAACCTTTGGTTTCTTA
TAGGGAAATCCATGGTGCACCTTCCAATTTCAGTTCCAGCCATCTGGAATCAAAGCACGTATACTGTGTAGATGTTAATGAAGAAAAGAC
TGAGAGCGGTAACTGGATGATAGGCAGTCGAGAAGAACGGAATATACGGAGCTGTGATTTTGAGAGCTCCCAATCATCTGTCATCAATGA
TACAGTTGTTAGGTTTTTAAATGATCGACCAGCAATTGATGCATTGCAAAATTCTGAATGTTTGATTAGGATGGGAGCTTCTATGAGAAC
TGAGGAAGAAATGCCTAACAGAACAAAAGGAAGTGAGAATAATTTGAAGCTTTCTGTGAATAACATGGCCCATGATACTGATCCAAAAGC
GTTACGACTAACTGACTCTTCTCCATCCTCTACTAGTACTTCTAATTCCCAAAGATTAGATATTCTAAAGCGGCGACAACATGATGTCAA
ACTGGAAAAACTTAAGGAACGGATTAGAAAACAGTGGGAACACTCAGAAGAAACAAATGGCCGGGGCCAGAAGCTGGGTCATATTGACCA
TCCAGTAATGGTTGTTAATGTTGATAACTCAGTAACAGCAAAAGTCAGAAAAGTGGCAACAGCACCACCTGCTCCAGCATATAAAGGTTT
CAACCCTTCAGAGACCAAGATTCGAACACCTGATGGGAAAGTGTGGCAGGAGGCTGAGTTTCAAAACATGAGTAGAGAACTGTATCGAGA
TTTAGCACTTCACTTTGCAGATGATATTTCTATAAAGGAGAAACCTGCTGAAAAAAGTAAAGAGAAGAAAGTAGTCAAGCCAGTACGAAA
AGTCCAAAAAGTAGCACAGTTATCAAGTACAGAATGCAGAACAGGTAGTAGTCATCTTATAAGTACATCTTCTTGGCGAGATGGACAAAA
ATTAGTAAAGAAGATTCTGGGACCTGCTCCCAGAATGGAGCCAAAAGAGCAAAGAACAGCATCAAGTGACAGAGGTGGAAGAGAAAGAAC
TGCTAAATCTGAAGCCACCAGTGTCCAACAGAAGGTCAATTTCTCTGAAGAAGGAGAAACTGAAGAAGATGATCAAGACAGCTCTCACAG
CAGTGTCACTACTGTTAAGGCCAGATCCAGGGATTCTGATGAATCTGGAGATAAAACCACCAGATCATCTAGTCAATATATAGAATCATT
TTGGCAGTCATCACAAAGTCAAAACTTCACAGCTCATGATAAGCAACCTTCAGTGCTAAGCTCAGGATATCAAAAAACTCCCCAGGAATG
GGCCCCACAAACTGCAAGAATAAGGACCAGGATGCAAAATGACAGCATTCTGAAATCAGAGCTTGGAAACCAGTCACCATCAACCTCCAG
CCGACAAGTGACTGGACAACCCCAAAATGCATCTTTTGTCAAGAGGAACCGGTGGTGGCTACTTCCTCTGATAGCTGCTCTTGCCTCTGG
GAGTTTTTGGTTCTTTAGTACTCCTGAGGTAGAAACCACTGCTGTTCAAGAGTTCCAGAACCAGATGAATCAACTTAAGAATAAGTACCA
AGGTCAAGATGAGAAGCTGTGGAAAAGGAGCCAAACATTCCTGGAAAAACATCTTAATAGCTCCCATCCTCGGTCTCAGCCTGCTATCTT
ACTGCTCACTGCTGCCCGAGATGCTGAAGAAGCACTTAGGTGTCTGAGTGAACAAATTGCTGATGCCTATTCTTCTTTTCGTAGTGTCCG
TGCCATCCGGATTGATGGGACAGATAAAGCTACTCAAGACAGTGATACTGTCAAACTAGAGGTAGACCAAGAACTGAGCAATGGATTTAA
GAATGGCCAGAATGCAGCTGTGGTACACCGCTTTGAGTCATTTCCCGCAGGCTCTACTTTGATCTTCTACAAATATTGTGACCATGAAAA
CGCGGCCTTCAAAGATGTAGCCTTAGTCCTGACTGTCTTATTGGAGGAAGAGACACTTGGAACAAGTCTAGGCCTAAAGGAAGTTGAAGA
AAAAGTAAGAGATTTTCTTAAAGTCAAGTTCACCAATTCTAACACACCCAACTCCTACAATCATATGGACCCAGACAAACTGAATGGCCT
CTGGAGCCGTATTTCTCACTTAGTTCTGCCTGTGCAACCTGAAAATGCCCTGAAAAGGGGCATCTGCTTATAAGAAGTGAGAGAGAAGAA
AAATCATGTCCCAAGTTCTGAGAATTGTTCACACTTTCTAACCAGAGACAGAATTCAGAGCTCTTTTTGAAAGAACTAGTTTCTTTTTAA
AGAAGTTAAGTGCTTACATAAACATGGAACATATAAATCATTCATTCAACCTAATTATCTGTGATATGAGAGAATCATTTCAGTTTCCAT
TGAGAGCTCTGTTAAAGGTATCTTAGGAGTGCAGATTATATGCAGTTCCTTAGAGAATCTGTTTTGATTCTGGGCTGAGTTATTACAGTT
ATGGTATGACCAGTGAGAGGGATTTGTGTCCTTTCTTATGAACCTTCCTGATTTTTTAACTTAGATTTCTCACTAAGTTTCCTGAGTTAT
TAGTAAGATTGCTCCCTAAATGTAACCAGGGATTTTCCCATTATGTTCCCTTTTATACCATTTAGGTGTGAGTTCCTTAGCTTCTGCCTA
TAGGAACATAAGTAATGAAAGGTCATCTAGGTGTGTGTTTGGAATTTTTTTCTTTTGTTTTTTGGAAAATGGAAAGAACAAGGCAAGGAA
GGAAAATTAATGGGGAAGCTGAAGGGAGGAAATGTTACAGTAATCCACTGAGATGTAGTTTAGTCAAACATAGGTATATGAACTGTTAAT
CTTGGTGGATTCCGTTGGGATTTGTTTTTTACATCTCCTTTTTCCTTCCTTGAAGAAAAATTCTTGGCTGTCCCAAGGATTCTTCATGTA
TATTGCAAAATTTAATATATTTGTTCACTTGAGTCTTAAGAGTAGGTCAGGCCAAGGCAGGTGGATCACCTGAGGTCAGAAGTTCAAGAC
CAGCCTGGCCAACATGGTGAAACCCCGTCTCTACTAAAAATACAAAAATTAGCTGGGCGTGGTGGTGCATGCCTGAAATCCCAGCTACTT
GGGAGGCTGAGGCAGGAGAATTGCTTGAACCCGGGAGGCGGAGGTTGCAGTAAGCCGAGACCATGCTTATTGCCCTCCAGTCTGGGCAAC
AAAAATGAAACTCCGTCTCAAAAAAAAAAAAGTAGGTCAATTCGTAACAGTTTATTTTGGACACACCCTGAAGCTTTTGTTTTGAATTAA
GAAATGAGTTTCAGGAATTGACAAACCATTTGTTAACCAGCTGTCCTGGGCTATTGAAGAAGATTTCATTTTCCGCGCATCCACTTGTTG
CAGTCCAAGTCCTCTAGTGCAACGCCATAGCAAATATAAAGATTTACTATGCACGTGATACATTTTATGGAGTGCCTCAAGCCAAGATAG
TGAATTTATATGAAGGGTGTGAAATGTATTTCTTTACTACTATAGTAGTTTAGTTATAACTTTGCATCTATAATTGAGCTTTCTCATCTG
TCAAATGCTATGGTTTTCTTAAAATGTTACAATTCTAGATCTATCCACCTTGTTTTTTTATTGTCTACAAACCATTAAATGTAAATATTG

>15859_15859_3_CEP350-TOR1AIP1_CEP350_chr1_179981210_ENST00000367607_TOR1AIP1_chr1_179869261_ENST00000528443_length(amino acids)=844AA_BP=663
MRSSKSKEVPLPNPRNSQSKDTVQADITTSWDALSQTKAALRHIENKLEVAPTSTAVCDSVMDTKKSSTSATRKISRKDGRYLDDSWVNA
PISKSTKSRKEKSRSPLRATTLESNVKKNNRVEFREPLVSYREIHGAPSNFSSSHLESKHVYCVDVNEEKTESGNWMIGSREERNIRSCD
FESSQSSVINDTVVRFLNDRPAIDALQNSECLIRMGASMRTEEEMPNRTKGSENNLKLSVNNMAHDTDPKALRLTDSSPSSTSTSNSQRL
DILKRRQHDVKLEKLKERIRKQWEHSEETNGRGQKLGHIDHPVMVVNVDNSVTAKVRKVATAPPAPAYKGFNPSETKIRTPDGKVWQEAE
FQNMSRELYRDLALHFADDISIKEKPAEKSKEKKVVKPVRKVQKVAQLSSTECRTGSSHLISTSSWRDGQKLVKKILGPAPRMEPKEQRT
ASSDRGGRERTAKSEATSVQQKVNFSEEGETEEDDQDSSHSSVTTVKARSRDSDESGDKTTRSSSQYIESFWQSSQSQNFTAHDKQPSVL
SSGYQKTPQEWAPQTARIRTRMQNDSILKSELGNQSPSTSSRQVTGQPQNASFVKRNRWWLLPLIAALASGSFWFFSTPEVETTAVQEFQ
NQMNQLKNKYQGQDEKLWKRSQTFLEKHLNSSHPRSQPAILLLTAARDAEEALRCLSEQIADAYSSFRSVRAIRIDGTDKATQDSDTVKL
EVDQELSNGFKNGQNAAVVHRFESFPAGSTLIFYKYCDHENAAFKDVALVLTVLLEEETLGTSLGLKEVEEKVRDFLKVKFTNSNTPNSY

--------------------------------------------------------------
>15859_15859_4_CEP350-TOR1AIP1_CEP350_chr1_179981210_ENST00000367607_TOR1AIP1_chr1_179869261_ENST00000606911_length(transcript)=9714nt_BP=1811nt
GCCCGACTGCTCCCGCCCTGCCTCGCGCCGCCGCCACAGCCGCTGCCGCTGGCGCCGCTCCTCCTCCGTGTCAGTTGTTGGGCTGTAATG
GCGACTGGGCCGCCCCTGACGAAGTGACTCCCGGGCCGGGGAGCGGGGCCAGACCTGCGCCAGAGAGAACTGCAGGGAGCCGCAGCTCGG
GGGGTGGCTTGCCCTGAGGGAGGGGAGGCAGCCTTTCCGCCTTGTCTTCCTTCCCAGCGGACCGGCGGATCCCCGGAGCCGGTGCGAGGA
GGGCACCCGGTGCGTCCCCGGAGCGGGGAGGCCAGGCCGGGCAGCCCTGGGGCCGGTCGGGGCGGCGTCACTGCACCCTCCGCCAGGCTC
CGCGGGATGCACCGTGGTAGCCGAGGGCGGAGGCGACACTCTCAGGTAAATTGGCAGGATGAGGAGCAGCAAATCAAAAGAGGTGCCTTT
ACCAAATCCAAGGAACTCTCAAAGCAAGGATACTGTTCAAGCAGATATAACCACATCGTGGGATGCACTTTCTCAAACCAAGGCTGCTCT
GAGACACATTGAAAATAAATTAGAAGTAGCCCCTACAAGTACAGCTGTGTGTGATTCTGTCATGGATACCAAGAAGTCTTCTACAAGTGC
TACTCGAAAAATAAGTAGAAAAGATGGTAGATACCTGGATGATTCTTGGGTTAATGCTCCAATCTCCAAATCCACTAAATCACGAAAAGA
GAAATCTCGTAGTCCTCTCAGGGCCACCACCCTGGAGAGTAATGTGAAGAAAAATAATCGTGTGGAATTTCGTGAACCTTTGGTTTCTTA
TAGGGAAATCCATGGTGCACCTTCCAATTTCAGTTCCAGCCATCTGGAATCAAAGCACGTATACTGTGTAGATGTTAATGAAGAAAAGAC
TGAGAGCGGTAACTGGATGATAGGCAGTCGAGAAGAACGGAATATACGGAGCTGTGATTTTGAGAGCTCCCAATCATCTGTCATCAATGA
TACAGTTGTTAGGTTTTTAAATGATCGACCAGCAATTGATGCATTGCAAAATTCTGAATGTTTGATTAGGATGGGAGCTTCTATGAGAAC
TGAGGAAGAAATGCCTAACAGAACAAAAGGAAGTGAGAATAATTTGAAGCTTTCTGTGAATAACATGGCCCATGATACTGATCCAAAAGC
GTTACGACTAACTGACTCTTCTCCATCCTCTACTAGTACTTCTAATTCCCAAAGATTAGATATTCTAAAGCGGCGACAACATGATGTCAA
ACTGGAAAAACTTAAGGAACGGATTAGAAAACAGTGGGAACACTCAGAAGAAACAAATGGCCGGGGCCAGAAGCTGGGTCATATTGACCA
TCCAGTAATGGTTGTTAATGTTGATAACTCAGTAACAGCAAAAGTCAGAAAAGTGGCAACAGCACCACCTGCTCCAGCATATAAAGGTTT
CAACCCTTCAGAGACCAAGATTCGAACACCTGATGGGAAAGTGTGGCAGGAGGCTGAGTTTCAAAACATGAGTAGAGAACTGTATCGAGA
TTTAGCACTTCACTTTGCAGATGATATTTCTATAAAGGAGAAACCTGCTGAAAAAAGTAAAGAGAAGAAAGTAGTCAAGCCAGTACGAAA
AGTCCAAAAAGTAGCACAGTTATCAAGTACAGAATGCAGAACAGGTAGTAGTCATCTTATAAGTACATCTTCTTGGCGAGATGGACAAAA
ATTAGTAAAGAAGATTCTGGGACCTGCTCCCAGAATGGAGCCAAAAGAGCAAAGAACAGCATCAAGTGACAGAGGTGGAAGAGAAAGAAC
TGCTAAATCTGAAGCCACCAGTGTCCAACAGAAGGTCAATTTCTCTGAAGAAGGAGAAACTGAAGAAGATGATCAAGACAGCTCTCACAG
CAGTGTCACTACTGTTAAGGCCAGATCCAGGGATTCTGATGAATCTGGAGATAAAACCACCAGATCATCTAGTCAATATATAGAATCATT
TTGGCAGTCATCACAAAGTCAAAACTTCACAGCTCATGATAAGCAACCTTCAGTGCTAAGCTCAGGATATCAAAAAACTCCCCAGGAATG
GGCCCCACAAACTGCAAGAATAAGGACCAGGATGCAAAATGACAGCATTCTGAAATCAGAGCTTGGAAACCAGTCACCATCAACCTCCAG
CCGACAAGTGACTGGACAACCCCAAAATGCATCTTTTGTCAAGAGGAACCGGTGGTGGCTACTTCCTCTGATAGCTGCTCTTGCCTCTGG
GAGTTTTTGGTTCTTTAGTACTCCTGAGGTAGAAACCACTGCTGTTCAAGAGTTCCAGAACCAGATGAATCAACTTAAGAATAAGTACCA
AGGTCAAGATGAGAAGCTGTGGAAAAGGAGCCAAACATTCCTGGAAAAACATCTTAATAGCTCCCATCCTCGGTCTCAGCCTGCTATCTT
ACTGCTCACTGCTGCCCGAGATGCTGAAGAAGCACTTAGGTGTCTGAGTGAACAAATTGCTGATGCCTATTCTTCTTTTCGTAGTGTCCG
TGCCATCCGGATTGATGGGACAGATAAAGCTACTCAAGACAGTGATACTGTCAAACTAGAGGTAGACCAAGAACTGAGCAATGGATTTAA
GAATGGCCAGAATGCAGCTGTGGTACACCGCTTTGAGTCATTTCCCGCAGGCTCTACTTTGATCTTCTACAAATATTGTGACCATGAAAA
CGCGGCCTTCAAAGATGTAGCCTTAGTCCTGACTGTCTTATTGGAGGAAGAGACACTTGGAACAAGTCTAGGCCTAAAGGAAGTTGAAGA
AAAAGTAAGAGATTTTCTTAAAGTCAAGTTCACCAATTCTAACACACCCAACTCCTACAATCATATGGACCCAGACAAACTGAATGGCCT
CTGGAGCCGTATTTCTCACTTAGTTCTGCCTGTGCAACCTGAAAATGCCCTGAAAAGGGGCATCTGCTTATAAGAAGTGAGAGAGAAGAA
AAATCATGTCCCAAGTTCTGAGAATTGTTCACACTTTCTAACCAGAGACAGAATTCAGAGCTCTTTTTGAAAGAACTAGTTTCTTTTTAA
AGAAGTTAAGTGCTTACATAAACATGGAACATATAAATCATTCATTCAACCTAATTATCTGTGATATGAGAGAATCATTTCAGTTTCCAT
TGAGAGCTCTGTTAAAGGTATCTTAGGAGTGCAGATTATATGCAGTTCCTTAGAGAATCTGTTTTGATTCTGGGCTGAGTTATTACAGTT
ATGGTATGACCAGTGAGAGGGATTTGTGTCCTTTCTTATGAACCTTCCTGATTTTTTAACTTAGATTTCTCACTAAGTTTCCTGAGTTAT
TAGTAAGATTGCTCCCTAAATGTAACCAGGGATTTTCCCATTATGTTCCCTTTTATACCATTTAGGTGTGAGTTCCTTAGCTTCTGCCTA
TAGGAACATAAGTAATGAAAGGTCATCTAGGTGTGTGTTTGGAATTTTTTTCTTTTGTTTTTTGGAAAATGGAAAGAACAAGGCAAGGAA
GGAAAATTAATGGGGAAGCTGAAGGGAGGAAATGTTACAGTAATCCACTGAGATGTAGTTTAGTCAAACATAGGTATATGAACTGTTAAT
CTTGGTGGATTCCGTTGGGATTTGTTTTTTACATCTCCTTTTTCCTTCCTTGAAGAAAAATTCTTGGCTGTCCCAAGGATTCTTCATGTA
TATTGCAAAATTTAATATATTTGTTCACTTGAGTCTTAAGAGTAGGTCAGGCCAAGGCAGGTGGATCACCTGAGGTCAGAAGTTCAAGAC
CAGCCTGGCCAACATGGTGAAACCCCGTCTCTACTAAAAATACAAAAATTAGCTGGGCGTGGTGGTGCATGCCTGAAATCCCAGCTACTT
GGGAGGCTGAGGCAGGAGAATTGCTTGAACCCGGGAGGCGGAGGTTGCAGTAAGCCGAGACCATGCTTATTGCCCTCCAGTCTGGGCAAC
AAAAATGAAACTCCGTCTCAAAAAAAAAAAAGTAGGTCAATTCGTAACAGTTTATTTTGGACACACCCTGAAGCTTTTGTTTTGAATTAA
GAAATGAGTTTCAGGAATTGACAAACCATTTGTTAACCAGCTGTCCTGGGCTATTGAAGAAGATTTCATTTTCCGCGCATCCACTTGTTG
CAGTCCAAGTCCTCTAGTGCAACGCCATAGCAAATATAAAGATTTACTATGCACGTGATACATTTTATGGAGTGCCTCAAGCCAAGATAG
TGAATTTATATGAAGGGTGTGAAATGTATTTCTTTACTACTATAGTAGTTTAGTTATAACTTTGCATCTATAATTGAGCTTTCTCATCTG
TCAAATGCTATGGTTTTCTTAAAATGTTACAATTCTAGATCTATCCACCTTGTTTTTTTATTGTCTACAAACCATTAAATGTAAATATTG
TTTTTAGAGTCAGTCATTGGCTTTGTCATTTACCCTTTGAGAGTTCCACAAGTGGTAGTAGAGTGGTTTAACGTCTTTCCTCTAGTACTA
CCAGTATTCATAAATGTATACCCCTTACTGTAATTTGTTCCTCTTAGAAGTCAGATCATCTGATTTATAGAGGATTATGAAAACCAGAGT
TTTTGAAAAGGCTTATTTTATACATACGTATTATATAGAGAAACAAATGTTTTTATTAAATGTTTCATTGACCCAAGTAATTTAAAAGTA
ATATGTTACCTATGTCTTTCAGGAAAAATAATTATAGCAGCTGATCTGTAAATGACTTTAAAAGCTATTTTAGTAATTTAAATAAATTTA
CTTTCTTGGTTTATACTCTCTATGTGTTATAAACTTAATGATTTATCATCTTTAAAAAAAGAAATCCAAGTATTTTCCTTGAACAATTGT
AGCAACTCTGGCTAGGAGAAACAAAAATCAAAGAACTGGAGCCATTTGCAAGTACATTGGTTAGAAGTGGAATAGCCGTAACTTTCCATT
TTATCTCGGCACTTAGGGTTTTTAAAAATACAGTTAAGTTAGATATTCCTGACTTAGCAAAAGAATCTCCACAGCAGCTTTTCTTTTTTT
TTTTTTTAAGTAGACATGGGATCTCGCTATATTGCCCAGGCTGTTTTTGAACTCTTGGCCTCAAGCAGTCCTCCTGCCTAAGCCTCCTAA
GTAGCTGGGATTACAGGCATAAGTCACTACACCTGGCTTCTTAACCTTTTCTTTATCACCTCCCTGAAGAACTTTTTTAGATTTTTTTCT
TAGTCACCCCTTCCCCATGATATTTCAACACCAGATATATACTATGTATCTGTTTATGGACTGTAAATGTTTTTTGCTTTATACAAAATA
GAATTTTTTTTTGTCCCCAATGAACCAATTTTCACCCCCATTGAGAATGCATGCTCAAGAGCATCCACGTTTTAGATAATTGCTGCCTAA
AATGTTCTATTTGCTATTCATGTTACTGTGATCCTTTTAGAAGGGAAAATTTATTTTTTATTTTTTTTATTTTTTATTTTTTTTATTTTT
GAGACAATCTCACTCTTGCCCAGGCTGGAGTGCAGTGGCGCAATCTCGGCTCACTGCAACCTCCGCCTCCCATGTTCAAGTGATTCTTCT
GCCTCAGCCTCCCGAGTAGCTGGGATTACAGGTTCACACCACCATGCCCGGCTAATTTTTTGTATTTTTAGTAGAGACGGAGTTTCACCA
TGTTGGCCAGGCTGGTCTTGAACTCCTGACCTCAGGTGATCCACCTGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCGCGG
AGCCTGGCCTAGAAAGGAAAATTTAAGTAAGATACCAGCTTCAGAATAGGAGCTAGGGTCTAGAGAAATGGAGCACATTGTAACTGGCTG
ACAACAGTGGCCCAGGAAAACCACAGTAACTTAATTTGAAACTTAATTTGCTTCCCTTGTTTTAATGACTTTTTAATATTTAAAGATGTT
TTCTAAACCTCTAATCCTCAAAACAAAAATTGGAAGTAAACTGATTTTCATTCAGTGAACTGCCATTTAGAAGTGATAGGGGTTTACATA
CTTTGTACCATTAGTTAACGCCTAAGCTAAAAGTATAATATCCAGTTTCCCTATGATCTCAAGTTTATGGAAAGTAGCCTTTCTTTTGGC
AGTGTAAACAAGCAGTTACATTAAATACGTAAAGATAATGCATTATTCTGCTATTTTGTCCTTATCAAGATCATGTAGTAAAATTTTGTG
GTATAAGAGGATAGTGTTTTTCCCTAAGGAAGAGGATTTTATTGGCATTAACCACCAAAGATGGGGTTCCTGAGCCTGGAAAACCAAGCT
GAGAAGGCTGCCATTGACTGGAAAAGGAGGAAATTCCTCCCTTGAATGCCCTCTTTCTGGCCTGGATTCTGAGAATTCCTTGTGTGTTTA
AGGACCCTTGTGGGTGGTAGAGAAACTAGTTCCTGTCACCTGAGCATAAACAGAAGAACCCCTTTGTACTCTACACCCCAGACATAATGA
ACTACTTGCAATTTCCTAAACACATCATTCACTTGTCTTTTGCACATTCTTAGACTCTTGGAATACTTCATTTCCTGCCCTCTCGCTTTC
TCCAATCTCATGTTCTGCTAATTTTTATTTGTCCTTAAAGTCTTCGTTTTCTTAGGGCAGCACTTCAGTGAAATCTTTCATAATTCCCTT
CCCCCAGATACTATTTTAGGTGCCTCCTGTTTTTTTTCTTTCTTTCTTTCTTTCTTTCTTTTTTCTTTTTCTTTTTTTGGTAGCTTAAAC
AATAAGACCTTTATTGTTACAAAACCCAGCAGCGTGAGGAGTTCCTGGGTTGGGTGAATTAGAGGCTGGAAAAATTCATCGCAAGCATTA
CAAGATAACCAATGATACCCCTGATGAAAGAAAACCTCTGCAAACTGCTAGCTGAAGCCAGCTCCTGTCCTTTTATCCAAAACTGGGTAG
TGTCCAGCCAAACCATTTTGGGGGTTGAATGAGTCACTTCAAAGGGCTCAAATGACTGGTGAATCTTCCAGATAAAAGGAGAGAACACAG
ACTTTCCTGCGCATTTTAAAGTGACTGAGGTGCTCCACACTCTGATTTATCCTTTATTACCCTGTGGCAGCATTAGCATACCCCTGCTAC
CACATGCATCTTGCAAGCAGTGATGTGTCATCAATATATGCACCGTGGCAATCACAGAATGCTCAAATATTTATTGAATAAAAAGAGCAA
GCCATACCTAATTATAGCTAGGTAAGTTGCATCTTAGTGTTTTATTTGCTTTCCCCACCCCCATCCCCCATTACGCCTAAGCCCTATCTA
AAAGTTGTATATAACTCATCTGGGTTTAGCAATGCTATGAATAAGGAAAAACAAAGAGGACCAATCTACGCCGTGGAAGGGAAATGCACT
TCTCTGATAGAGACAGTGATCATTACAGGTCCTCAAGGGAAAGGTGGAATATCAAGGGAAAAGACTGGGAAGCTGTGAGGTCTTTCCACA
GTGATATTTGGCATTTGCATTTTCTAAAAATAGCTAGCAAGTATTCTTCCATCTTTTTCTGTTGCCTAAGAGGGTATTATAATTCAGATA
AAAGATGGCTATGGATGTACGAACAAGATGGATAAGAAAAATATTCGAGAATTAGAACTGACCAGATTTGATTGACTGTAGAAGTGCTGA
AAATTTCTCTTTCTTCTGTTTAGCTCATATATCTTCTCCCCAGATACTAAGCATAAAGTGATAGACTAAATTCCTATCTCTGCATGTCAA
TATGTTGACTTTTAGTTTGAAGTAGAGCCACACATATTTGGTCAGAAATTGATTGTAGAGAATAAAAACCCTGTCCAACCAGGAAATGAG
CAAAAGAGGGCTGGGGTGAAGATTGCAAGAATATACATCTCAGACTCCAGGAAAAGGAAAATACAGGAACTGTGAAGACTGTTTTCATTT
GGAGACCAGCAGCCATTCCCTCTGTCTCTCTATTGCTGCTACCCAATTAGCAACTTCCCCTTTGTGACTTAAATGCCAAAAAGATGACAT
TAATGGCTCAATTCAGTGTATGAAGGATTCCTGAGAAGAATATATGATAAAGCATAGCTTCCTAGGTCACCCTTTTAACAGGGACCAGGA
GTTTGGGTTGTGGTAGGGCTGTGTCCTGAGGTCAGGCCAAGAAGTGGGCTGATATGTTAAAGGACAACTGAATACTTCTTCAACTATATA
AAGACCTTCTATATGTAATGCCATGCTATGTCATTAATGGCATTTCATTTTAGCTTTTTAAAAAACCCAACGAAGGGAAATTCAAGGTAA
TGGAAACATTTTAAGTTTTAAAATCTGAGTCCTGGTCATGGGTCTACTACAAATGTGATTTCTTCCCATTGCTTCTGTTTCTCTAGGCTA
AACCAGGAAGATAGTTGTCAAAACTTCGGGTACTATTTTAACATACATCAGCACTTGTTAATTTGCTGTAATTCCCTCAATAGAACACCA
AGCTTTAGTTTTCAGTATGTTTCTTGGGCAAGTGAGGTGGTAGGTGGCCATGTACTAGATCAAACTTGATTTTCTAGGGATTGTTTTCCC
ACTTTTAGAGAATACCATTCTTAGGCTAAACTCAATTACAGAATCTACTGCATGCTATACAGCCCTCTATAGAAATATTCACCCTGAGTA
GTTAATTATGTTTCTTAATGGGTAAATGTTTTATCTAGTCCCTCTTTTTTTTTAATTTGATAAAATCCAGATCTCTCAGAGCTTAAATAC
ACTTCCTCTTATTTTCCCTACAACAAATATGGAAAAGATCTATAATATATATTTGAATATGTATTAAGTTGTTCCTCACCCTTTTCTATT
TTTTATTAGCTATTGAGTGTTTATTAATGCTTCAAACACTTCCAAGTGCTTTATGTATATTAACTGATTTAATTCTTAAGTTACTCTATG
AGATGGTATTATTATCCCAACTTAATAGGAAACTGAAGCACAGTGAGCTAAAGTAACTCTCGAAGTGGTGGAGCAGAGAGATGAACCCAG
GCAGTCTGACTTTAGAACATCTATGCTTACCACTATGATGTTCTCAAGGACCCCATTCTGAATATAGGAATAAACAAATTCAGTTTCTCC
CACTTTAATCTCACAACACCCTTCTGACTCCAGATGTGTGTGGAGGGGGGTTCCCCACGCATTAAGCAAATAAGCAATTTTGCAGCAGAC
ACCAGCTGGGTGTCCTCTAATTCAATTCACTTCTTACACTACCTGGAGATAGCATCAGATACCATAGGTTGAAGGCTCAGTGCCACAAGA
TGGCTCCCACTTCAGATGACAATCAGAAGCCCCAGATGGTGACCAAGGGTCCTAACCAACTAGCTATAAGTTAGGGTTCCCATAACCCCT
TCTTGAGCTCCATTAGTTTGCTAGAGAGGCTCACAGAACTCGGAAACACTATACAGTCATGCTGTACATAATGACATTTCAATGTCAGCC
TGCATAGACAATGGTGATCCCATAAGATTATAATACTGTATTTTTACTGTACCTTTTCTATGTTTAGGTATGTTTAGATAGACAAATAGT
CAATCCTTGAACAACTTGGGTTTGAACTGTGTGGGTCCATTTATACATGGATTTTTTTTCAATAAATGTATTGGAAAATTTTTTGGAGAT

>15859_15859_4_CEP350-TOR1AIP1_CEP350_chr1_179981210_ENST00000367607_TOR1AIP1_chr1_179869261_ENST00000606911_length(amino acids)=844AA_BP=663
MRSSKSKEVPLPNPRNSQSKDTVQADITTSWDALSQTKAALRHIENKLEVAPTSTAVCDSVMDTKKSSTSATRKISRKDGRYLDDSWVNA
PISKSTKSRKEKSRSPLRATTLESNVKKNNRVEFREPLVSYREIHGAPSNFSSSHLESKHVYCVDVNEEKTESGNWMIGSREERNIRSCD
FESSQSSVINDTVVRFLNDRPAIDALQNSECLIRMGASMRTEEEMPNRTKGSENNLKLSVNNMAHDTDPKALRLTDSSPSSTSTSNSQRL
DILKRRQHDVKLEKLKERIRKQWEHSEETNGRGQKLGHIDHPVMVVNVDNSVTAKVRKVATAPPAPAYKGFNPSETKIRTPDGKVWQEAE
FQNMSRELYRDLALHFADDISIKEKPAEKSKEKKVVKPVRKVQKVAQLSSTECRTGSSHLISTSSWRDGQKLVKKILGPAPRMEPKEQRT
ASSDRGGRERTAKSEATSVQQKVNFSEEGETEEDDQDSSHSSVTTVKARSRDSDESGDKTTRSSSQYIESFWQSSQSQNFTAHDKQPSVL
SSGYQKTPQEWAPQTARIRTRMQNDSILKSELGNQSPSTSSRQVTGQPQNASFVKRNRWWLLPLIAALASGSFWFFSTPEVETTAVQEFQ
NQMNQLKNKYQGQDEKLWKRSQTFLEKHLNSSHPRSQPAILLLTAARDAEEALRCLSEQIADAYSSFRSVRAIRIDGTDKATQDSDTVKL
EVDQELSNGFKNGQNAAVVHRFESFPAGSTLIFYKYCDHENAAFKDVALVLTVLLEEETLGTSLGLKEVEEKVRDFLKVKFTNSNTPNSY

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Fusion Gene PPI Analysis for CEP350-TOR1AIP1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
TgeneTOR1AIP1chr1:179966310chr1:179869261ENST00000435319210356_58382.33333333333333463.0TOR1A
TgeneTOR1AIP1chr1:179981210chr1:179869261ENST00000435319210356_58382.33333333333333463.0TOR1A


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for CEP350-TOR1AIP1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for CEP350-TOR1AIP1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneC0009918Contracture of joint1GENOMICS_ENGLAND
TgeneC4310731MYOPATHY, AUTOSOMAL RECESSIVE, WITH RIGID SPINE AND DISTAL JOINT CONTRACTURES1CTD_human;GENOMICS_ENGLAND;ORPHANET