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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:DGCR2-CLTCL1 (FusionGDB2 ID:HG9993TG8218)

Fusion Gene Summary for DGCR2-CLTCL1

check button Fusion gene summary
Fusion gene informationFusion gene name: DGCR2-CLTCL1
Fusion gene ID: hg9993tg8218
HgeneTgene
Gene symbol

DGCR2

CLTCL1

Gene ID

9993

8218

Gene nameDiGeorge syndrome critical region gene 2clathrin heavy chain like 1
SynonymsDGS-C|IDD|LAN|SEZ-12CHC22|CLH22|CLTCL|CLTD
Cytomap('DGCR2')('CLTCL1')

22q11.21

22q11.21

Type of geneprotein-codingprotein-coding
Descriptionintegral membrane protein DGCR2/IDDDiGeorge syndrome critical region protein 2integral membrane protein deleted in DiGeorge syndromeclathrin heavy chain 2CLH-22Clathrin, heavy polypeptide Dclathrin heavy chain on chromosome 22clathrin, heavy polypeptide-like 1
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000545799, ENST00000263196, 
ENST00000537045, ENST00000473832, 
Fusion gene scores* DoF score16 X 15 X 8=19209 X 7 X 7=441
# samples 2112
** MAII scorelog2(21/1920*10)=-3.1926450779424
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(12/441*10)=-1.877744249949
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: DGCR2 [Title/Abstract] AND CLTCL1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointDGCR2(19076881)-CLTCL1(19263353), # samples:3
Anticipated loss of major functional domain due to fusion event.DGCR2-CLTCL1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
DGCR2-CLTCL1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
DGCR2-CLTCL1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
DGCR2-CLTCL1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
DGCR2-CLTCL1 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
DGCR2-CLTCL1 seems lost the major protein functional domain in Tgene partner, which is a CGC due to the frame-shifted ORF.
DGCR2-CLTCL1 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneCLTCL1

GO:0000278

mitotic cell cycle

19509056

TgeneCLTCL1

GO:0000278

mitotic cell cycle

20065094

TgeneCLTCL1

GO:0006898

receptor-mediated endocytosis

19509056


check buttonFusion gene breakpoints across DGCR2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across CLTCL1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-A7-A26G-01ADGCR2chr22

19076881

-CLTCL1chr22

19263353

-
ChimerDB4BRCATCGA-A7-A4SC-01ADGCR2chr22

19076881

-CLTCL1chr22

19178947

-
ChimerDB4STADTCGA-CD-A489-01ADGCR2chr22

19044499

-CLTCL1chr22

19263353

-


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Fusion Gene ORF analysis for DGCR2-CLTCL1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000545799ENST00000263200DGCR2chr22

19044499

-CLTCL1chr22

19263353

-
3UTR-3CDSENST00000545799ENST00000353891DGCR2chr22

19044499

-CLTCL1chr22

19263353

-
3UTR-3CDSENST00000545799ENST00000427926DGCR2chr22

19044499

-CLTCL1chr22

19263353

-
3UTR-intronENST00000545799ENST00000442042DGCR2chr22

19044499

-CLTCL1chr22

19263353

-
5CDS-5UTRENST00000263196ENST00000442042DGCR2chr22

19076881

-CLTCL1chr22

19178947

-
5CDS-5UTRENST00000545799ENST00000442042DGCR2chr22

19076881

-CLTCL1chr22

19178947

-
5CDS-intronENST00000263196ENST00000442042DGCR2chr22

19076881

-CLTCL1chr22

19263353

-
5CDS-intronENST00000263196ENST00000442042DGCR2chr22

19044499

-CLTCL1chr22

19263353

-
5CDS-intronENST00000537045ENST00000442042DGCR2chr22

19044499

-CLTCL1chr22

19263353

-
5CDS-intronENST00000545799ENST00000442042DGCR2chr22

19076881

-CLTCL1chr22

19263353

-
Frame-shiftENST00000263196ENST00000263200DGCR2chr22

19076881

-CLTCL1chr22

19263353

-
Frame-shiftENST00000263196ENST00000263200DGCR2chr22

19076881

-CLTCL1chr22

19178947

-
Frame-shiftENST00000263196ENST00000263200DGCR2chr22

19044499

-CLTCL1chr22

19263353

-
Frame-shiftENST00000263196ENST00000353891DGCR2chr22

19076881

-CLTCL1chr22

19263353

-
Frame-shiftENST00000263196ENST00000353891DGCR2chr22

19076881

-CLTCL1chr22

19178947

-
Frame-shiftENST00000263196ENST00000353891DGCR2chr22

19044499

-CLTCL1chr22

19263353

-
Frame-shiftENST00000263196ENST00000427926DGCR2chr22

19076881

-CLTCL1chr22

19263353

-
Frame-shiftENST00000263196ENST00000427926DGCR2chr22

19076881

-CLTCL1chr22

19178947

-
Frame-shiftENST00000263196ENST00000427926DGCR2chr22

19044499

-CLTCL1chr22

19263353

-
Frame-shiftENST00000537045ENST00000263200DGCR2chr22

19044499

-CLTCL1chr22

19263353

-
Frame-shiftENST00000537045ENST00000353891DGCR2chr22

19044499

-CLTCL1chr22

19263353

-
Frame-shiftENST00000537045ENST00000427926DGCR2chr22

19044499

-CLTCL1chr22

19263353

-
In-frameENST00000545799ENST00000263200DGCR2chr22

19076881

-CLTCL1chr22

19263353

-
In-frameENST00000545799ENST00000263200DGCR2chr22

19076881

-CLTCL1chr22

19178947

-
In-frameENST00000545799ENST00000353891DGCR2chr22

19076881

-CLTCL1chr22

19263353

-
In-frameENST00000545799ENST00000353891DGCR2chr22

19076881

-CLTCL1chr22

19178947

-
In-frameENST00000545799ENST00000427926DGCR2chr22

19076881

-CLTCL1chr22

19263353

-
In-frameENST00000545799ENST00000427926DGCR2chr22

19076881

-CLTCL1chr22

19178947

-
intron-3CDSENST00000473832ENST00000263200DGCR2chr22

19076881

-CLTCL1chr22

19263353

-
intron-3CDSENST00000473832ENST00000263200DGCR2chr22

19076881

-CLTCL1chr22

19178947

-
intron-3CDSENST00000473832ENST00000263200DGCR2chr22

19044499

-CLTCL1chr22

19263353

-
intron-3CDSENST00000473832ENST00000353891DGCR2chr22

19076881

-CLTCL1chr22

19263353

-
intron-3CDSENST00000473832ENST00000353891DGCR2chr22

19076881

-CLTCL1chr22

19178947

-
intron-3CDSENST00000473832ENST00000353891DGCR2chr22

19044499

-CLTCL1chr22

19263353

-
intron-3CDSENST00000473832ENST00000427926DGCR2chr22

19076881

-CLTCL1chr22

19263353

-
intron-3CDSENST00000473832ENST00000427926DGCR2chr22

19076881

-CLTCL1chr22

19178947

-
intron-3CDSENST00000473832ENST00000427926DGCR2chr22

19044499

-CLTCL1chr22

19263353

-
intron-3CDSENST00000537045ENST00000263200DGCR2chr22

19076881

-CLTCL1chr22

19263353

-
intron-3CDSENST00000537045ENST00000263200DGCR2chr22

19076881

-CLTCL1chr22

19178947

-
intron-3CDSENST00000537045ENST00000353891DGCR2chr22

19076881

-CLTCL1chr22

19263353

-
intron-3CDSENST00000537045ENST00000353891DGCR2chr22

19076881

-CLTCL1chr22

19178947

-
intron-3CDSENST00000537045ENST00000427926DGCR2chr22

19076881

-CLTCL1chr22

19263353

-
intron-3CDSENST00000537045ENST00000427926DGCR2chr22

19076881

-CLTCL1chr22

19178947

-
intron-5UTRENST00000473832ENST00000442042DGCR2chr22

19076881

-CLTCL1chr22

19178947

-
intron-5UTRENST00000537045ENST00000442042DGCR2chr22

19076881

-CLTCL1chr22

19178947

-
intron-intronENST00000473832ENST00000442042DGCR2chr22

19076881

-CLTCL1chr22

19263353

-
intron-intronENST00000473832ENST00000442042DGCR2chr22

19044499

-CLTCL1chr22

19263353

-
intron-intronENST00000537045ENST00000442042DGCR2chr22

19076881

-CLTCL1chr22

19263353

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)
BP loci
(transcript)
Predicted start
(transcript)
Predicted stop
(transcript)
Seq length
(amino acids)
ENST00000545799DGCR2chr2219076881-ENST00000353891CLTCL1chr2219263353-563040325651121618
ENST00000545799DGCR2chr2219076881-ENST00000263200CLTCL1chr2219263353-580140325652831675
ENST00000545799DGCR2chr2219076881-ENST00000427926CLTCL1chr2219263353-579840325652831675
ENST00000545799DGCR2chr2219076881-ENST00000353891CLTCL1chr2219178947-1481403256963235
ENST00000545799DGCR2chr2219076881-ENST00000263200CLTCL1chr2219178947-16524032561134292
ENST00000545799DGCR2chr2219076881-ENST00000427926CLTCL1chr2219178947-16494032561134292

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000545799ENST00000353891DGCR2chr2219076881-CLTCL1chr2219263353-0.0038447860.9961552
ENST00000545799ENST00000263200DGCR2chr2219076881-CLTCL1chr2219263353-0.0038226580.9961773
ENST00000545799ENST00000427926DGCR2chr2219076881-CLTCL1chr2219263353-0.0038319810.99616796
ENST00000545799ENST00000353891DGCR2chr2219076881-CLTCL1chr2219178947-0.0054508980.9945491
ENST00000545799ENST00000263200DGCR2chr2219076881-CLTCL1chr2219178947-0.0057757430.99422425
ENST00000545799ENST00000427926DGCR2chr2219076881-CLTCL1chr2219178947-0.0057367810.99426323

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Fusion Genomic Features for DGCR2-CLTCL1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

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Fusion Protein Features for DGCR2-CLTCL1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr22:19076881/chr22:19263353)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneDGCR2chr22:19076881chr22:19178947ENST00000263196-21028_6867551.0DomainLDL-receptor class A
HgeneDGCR2chr22:19076881chr22:19263353ENST00000263196-21028_6867551.0DomainLDL-receptor class A
TgeneCLTCL1chr22:19076881chr22:19178947ENST0000026320025331551_164013971712.3333333333333RegionTrimerization
TgeneCLTCL1chr22:19076881chr22:19178947ENST0000035389125321551_164013971665.0RegionTrimerization
TgeneCLTCL1chr22:19076881chr22:19178947ENST0000042792626341551_164013971710.6666666666667RegionTrimerization
TgeneCLTCL1chr22:19076881chr22:19263353ENST00000263200033108_149141712.3333333333333RegionNote=WD40-like repeat 3
TgeneCLTCL1chr22:19076881chr22:19263353ENST000002632000331213_1522141712.3333333333333RegionInvolved in binding clathrin light chain
TgeneCLTCL1chr22:19076881chr22:19263353ENST00000263200033150_195141712.3333333333333RegionNote=WD40-like repeat 4
TgeneCLTCL1chr22:19076881chr22:19263353ENST000002632000331551_1640141712.3333333333333RegionTrimerization
TgeneCLTCL1chr22:19076881chr22:19263353ENST00000263200033196_257141712.3333333333333RegionNote=WD40-like repeat 5
TgeneCLTCL1chr22:19076881chr22:19263353ENST0000026320003324_67141712.3333333333333RegionNote=WD40-like repeat 1
TgeneCLTCL1chr22:19076881chr22:19263353ENST00000263200033258_301141712.3333333333333RegionNote=WD40-like repeat 6
TgeneCLTCL1chr22:19076881chr22:19263353ENST00000263200033302_330141712.3333333333333RegionNote=WD40-like repeat 7
TgeneCLTCL1chr22:19076881chr22:19263353ENST00000263200033449_465141712.3333333333333RegionBinding site for the uncoating ATPase%2C involved in lattice disassembly
TgeneCLTCL1chr22:19076881chr22:19263353ENST00000263200033480_523141712.3333333333333RegionNote=Flexible linker
TgeneCLTCL1chr22:19076881chr22:19263353ENST00000263200033524_1640141712.3333333333333RegionNote=Heavy chain arm
TgeneCLTCL1chr22:19076881chr22:19263353ENST00000263200033524_634141712.3333333333333RegionNote=Distal segment
TgeneCLTCL1chr22:19076881chr22:19263353ENST00000263200033639_1640141712.3333333333333RegionNote=Proximal segment
TgeneCLTCL1chr22:19076881chr22:19263353ENST0000026320003368_107141712.3333333333333RegionNote=WD40-like repeat 2
TgeneCLTCL1chr22:19076881chr22:19263353ENST00000353891032108_149141665.0RegionNote=WD40-like repeat 3
TgeneCLTCL1chr22:19076881chr22:19263353ENST000003538910321213_1522141665.0RegionInvolved in binding clathrin light chain
TgeneCLTCL1chr22:19076881chr22:19263353ENST00000353891032150_195141665.0RegionNote=WD40-like repeat 4
TgeneCLTCL1chr22:19076881chr22:19263353ENST000003538910321551_1640141665.0RegionTrimerization
TgeneCLTCL1chr22:19076881chr22:19263353ENST00000353891032196_257141665.0RegionNote=WD40-like repeat 5
TgeneCLTCL1chr22:19076881chr22:19263353ENST0000035389103224_67141665.0RegionNote=WD40-like repeat 1
TgeneCLTCL1chr22:19076881chr22:19263353ENST00000353891032258_301141665.0RegionNote=WD40-like repeat 6
TgeneCLTCL1chr22:19076881chr22:19263353ENST00000353891032302_330141665.0RegionNote=WD40-like repeat 7
TgeneCLTCL1chr22:19076881chr22:19263353ENST00000353891032449_465141665.0RegionBinding site for the uncoating ATPase%2C involved in lattice disassembly
TgeneCLTCL1chr22:19076881chr22:19263353ENST00000353891032480_523141665.0RegionNote=Flexible linker
TgeneCLTCL1chr22:19076881chr22:19263353ENST00000353891032524_1640141665.0RegionNote=Heavy chain arm
TgeneCLTCL1chr22:19076881chr22:19263353ENST00000353891032524_634141665.0RegionNote=Distal segment
TgeneCLTCL1chr22:19076881chr22:19263353ENST00000353891032639_1640141665.0RegionNote=Proximal segment
TgeneCLTCL1chr22:19076881chr22:19263353ENST0000035389103268_107141665.0RegionNote=WD40-like repeat 2
TgeneCLTCL1chr22:19076881chr22:19263353ENST00000427926034108_149141710.6666666666667RegionNote=WD40-like repeat 3
TgeneCLTCL1chr22:19076881chr22:19263353ENST000004279260341213_1522141710.6666666666667RegionInvolved in binding clathrin light chain
TgeneCLTCL1chr22:19076881chr22:19263353ENST00000427926034150_195141710.6666666666667RegionNote=WD40-like repeat 4
TgeneCLTCL1chr22:19076881chr22:19263353ENST000004279260341551_1640141710.6666666666667RegionTrimerization
TgeneCLTCL1chr22:19076881chr22:19263353ENST00000427926034196_257141710.6666666666667RegionNote=WD40-like repeat 5
TgeneCLTCL1chr22:19076881chr22:19263353ENST0000042792603424_67141710.6666666666667RegionNote=WD40-like repeat 1
TgeneCLTCL1chr22:19076881chr22:19263353ENST00000427926034258_301141710.6666666666667RegionNote=WD40-like repeat 6
TgeneCLTCL1chr22:19076881chr22:19263353ENST00000427926034302_330141710.6666666666667RegionNote=WD40-like repeat 7
TgeneCLTCL1chr22:19076881chr22:19263353ENST00000427926034449_465141710.6666666666667RegionBinding site for the uncoating ATPase%2C involved in lattice disassembly
TgeneCLTCL1chr22:19076881chr22:19263353ENST00000427926034480_523141710.6666666666667RegionNote=Flexible linker
TgeneCLTCL1chr22:19076881chr22:19263353ENST00000427926034524_1640141710.6666666666667RegionNote=Heavy chain arm
TgeneCLTCL1chr22:19076881chr22:19263353ENST00000427926034524_634141710.6666666666667RegionNote=Distal segment
TgeneCLTCL1chr22:19076881chr22:19263353ENST00000427926034639_1640141710.6666666666667RegionNote=Proximal segment
TgeneCLTCL1chr22:19076881chr22:19263353ENST0000042792603468_107141710.6666666666667RegionNote=WD40-like repeat 2
TgeneCLTCL1chr22:19076881chr22:19178947ENST0000026320025331423_156613971712.3333333333333RepeatNote=CHCR 7
TgeneCLTCL1chr22:19076881chr22:19178947ENST0000035389125321423_156613971665.0RepeatNote=CHCR 7
TgeneCLTCL1chr22:19076881chr22:19178947ENST0000042792626341423_156613971710.6666666666667RepeatNote=CHCR 7
TgeneCLTCL1chr22:19076881chr22:19263353ENST000002632000331128_1269141712.3333333333333RepeatNote=CHCR 5
TgeneCLTCL1chr22:19076881chr22:19263353ENST000002632000331274_1420141712.3333333333333RepeatNote=CHCR 6
TgeneCLTCL1chr22:19076881chr22:19263353ENST000002632000331423_1566141712.3333333333333RepeatNote=CHCR 7
TgeneCLTCL1chr22:19076881chr22:19263353ENST00000263200033537_683141712.3333333333333RepeatNote=CHCR 1
TgeneCLTCL1chr22:19076881chr22:19263353ENST00000263200033686_828141712.3333333333333RepeatNote=CHCR 2
TgeneCLTCL1chr22:19076881chr22:19263353ENST00000263200033833_972141712.3333333333333RepeatNote=CHCR 3
TgeneCLTCL1chr22:19076881chr22:19263353ENST00000263200033979_1124141712.3333333333333RepeatNote=CHCR 4
TgeneCLTCL1chr22:19076881chr22:19263353ENST000003538910321128_1269141665.0RepeatNote=CHCR 5
TgeneCLTCL1chr22:19076881chr22:19263353ENST000003538910321274_1420141665.0RepeatNote=CHCR 6
TgeneCLTCL1chr22:19076881chr22:19263353ENST000003538910321423_1566141665.0RepeatNote=CHCR 7
TgeneCLTCL1chr22:19076881chr22:19263353ENST00000353891032537_683141665.0RepeatNote=CHCR 1
TgeneCLTCL1chr22:19076881chr22:19263353ENST00000353891032686_828141665.0RepeatNote=CHCR 2
TgeneCLTCL1chr22:19076881chr22:19263353ENST00000353891032833_972141665.0RepeatNote=CHCR 3
TgeneCLTCL1chr22:19076881chr22:19263353ENST00000353891032979_1124141665.0RepeatNote=CHCR 4
TgeneCLTCL1chr22:19076881chr22:19263353ENST000004279260341128_1269141710.6666666666667RepeatNote=CHCR 5
TgeneCLTCL1chr22:19076881chr22:19263353ENST000004279260341274_1420141710.6666666666667RepeatNote=CHCR 6
TgeneCLTCL1chr22:19076881chr22:19263353ENST000004279260341423_1566141710.6666666666667RepeatNote=CHCR 7
TgeneCLTCL1chr22:19076881chr22:19263353ENST00000427926034537_683141710.6666666666667RepeatNote=CHCR 1
TgeneCLTCL1chr22:19076881chr22:19263353ENST00000427926034686_828141710.6666666666667RepeatNote=CHCR 2
TgeneCLTCL1chr22:19076881chr22:19263353ENST00000427926034833_972141710.6666666666667RepeatNote=CHCR 3
TgeneCLTCL1chr22:19076881chr22:19263353ENST00000427926034979_1124141710.6666666666667RepeatNote=CHCR 4

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneDGCR2chr22:19076881chr22:19178947ENST00000263196-210115_24167551.0DomainC-type lectin
HgeneDGCR2chr22:19076881chr22:19178947ENST00000263196-210270_33367551.0DomainNote=VWFC
HgeneDGCR2chr22:19076881chr22:19178947ENST00000537045-19115_2410510.0DomainC-type lectin
HgeneDGCR2chr22:19076881chr22:19178947ENST00000537045-19270_3330510.0DomainNote=VWFC
HgeneDGCR2chr22:19076881chr22:19178947ENST00000537045-1928_680510.0DomainLDL-receptor class A
HgeneDGCR2chr22:19076881chr22:19263353ENST00000263196-210115_24167551.0DomainC-type lectin
HgeneDGCR2chr22:19076881chr22:19263353ENST00000263196-210270_33367551.0DomainNote=VWFC
HgeneDGCR2chr22:19076881chr22:19263353ENST00000537045-19115_2410510.0DomainC-type lectin
HgeneDGCR2chr22:19076881chr22:19263353ENST00000537045-19270_3330510.0DomainNote=VWFC
HgeneDGCR2chr22:19076881chr22:19263353ENST00000537045-1928_680510.0DomainLDL-receptor class A
HgeneDGCR2chr22:19076881chr22:19178947ENST00000263196-21021_34967551.0Topological domainExtracellular
HgeneDGCR2chr22:19076881chr22:19178947ENST00000263196-210369_55067551.0Topological domainCytoplasmic
HgeneDGCR2chr22:19076881chr22:19178947ENST00000537045-1921_3490510.0Topological domainExtracellular
HgeneDGCR2chr22:19076881chr22:19178947ENST00000537045-19369_5500510.0Topological domainCytoplasmic
HgeneDGCR2chr22:19076881chr22:19263353ENST00000263196-21021_34967551.0Topological domainExtracellular
HgeneDGCR2chr22:19076881chr22:19263353ENST00000263196-210369_55067551.0Topological domainCytoplasmic
HgeneDGCR2chr22:19076881chr22:19263353ENST00000537045-1921_3490510.0Topological domainExtracellular
HgeneDGCR2chr22:19076881chr22:19263353ENST00000537045-19369_5500510.0Topological domainCytoplasmic
HgeneDGCR2chr22:19076881chr22:19178947ENST00000263196-210350_36867551.0TransmembraneHelical
HgeneDGCR2chr22:19076881chr22:19178947ENST00000537045-19350_3680510.0TransmembraneHelical
HgeneDGCR2chr22:19076881chr22:19263353ENST00000263196-210350_36867551.0TransmembraneHelical
HgeneDGCR2chr22:19076881chr22:19263353ENST00000537045-19350_3680510.0TransmembraneHelical
TgeneCLTCL1chr22:19076881chr22:19178947ENST000002632002533108_14913971712.3333333333333RegionNote=WD40-like repeat 3
TgeneCLTCL1chr22:19076881chr22:19178947ENST0000026320025331213_152213971712.3333333333333RegionInvolved in binding clathrin light chain
TgeneCLTCL1chr22:19076881chr22:19178947ENST000002632002533150_19513971712.3333333333333RegionNote=WD40-like repeat 4
TgeneCLTCL1chr22:19076881chr22:19178947ENST000002632002533196_25713971712.3333333333333RegionNote=WD40-like repeat 5
TgeneCLTCL1chr22:19076881chr22:19178947ENST00000263200253324_6713971712.3333333333333RegionNote=WD40-like repeat 1
TgeneCLTCL1chr22:19076881chr22:19178947ENST000002632002533258_30113971712.3333333333333RegionNote=WD40-like repeat 6
TgeneCLTCL1chr22:19076881chr22:19178947ENST0000026320025332_47913971712.3333333333333RegionNote=Globular terminal domain
TgeneCLTCL1chr22:19076881chr22:19178947ENST000002632002533302_33013971712.3333333333333RegionNote=WD40-like repeat 7
TgeneCLTCL1chr22:19076881chr22:19178947ENST000002632002533449_46513971712.3333333333333RegionBinding site for the uncoating ATPase%2C involved in lattice disassembly
TgeneCLTCL1chr22:19076881chr22:19178947ENST000002632002533480_52313971712.3333333333333RegionNote=Flexible linker
TgeneCLTCL1chr22:19076881chr22:19178947ENST000002632002533524_164013971712.3333333333333RegionNote=Heavy chain arm
TgeneCLTCL1chr22:19076881chr22:19178947ENST000002632002533524_63413971712.3333333333333RegionNote=Distal segment
TgeneCLTCL1chr22:19076881chr22:19178947ENST000002632002533639_164013971712.3333333333333RegionNote=Proximal segment
TgeneCLTCL1chr22:19076881chr22:19178947ENST00000263200253368_10713971712.3333333333333RegionNote=WD40-like repeat 2
TgeneCLTCL1chr22:19076881chr22:19178947ENST000003538912532108_14913971665.0RegionNote=WD40-like repeat 3
TgeneCLTCL1chr22:19076881chr22:19178947ENST0000035389125321213_152213971665.0RegionInvolved in binding clathrin light chain
TgeneCLTCL1chr22:19076881chr22:19178947ENST000003538912532150_19513971665.0RegionNote=WD40-like repeat 4
TgeneCLTCL1chr22:19076881chr22:19178947ENST000003538912532196_25713971665.0RegionNote=WD40-like repeat 5
TgeneCLTCL1chr22:19076881chr22:19178947ENST00000353891253224_6713971665.0RegionNote=WD40-like repeat 1
TgeneCLTCL1chr22:19076881chr22:19178947ENST000003538912532258_30113971665.0RegionNote=WD40-like repeat 6
TgeneCLTCL1chr22:19076881chr22:19178947ENST0000035389125322_47913971665.0RegionNote=Globular terminal domain
TgeneCLTCL1chr22:19076881chr22:19178947ENST000003538912532302_33013971665.0RegionNote=WD40-like repeat 7
TgeneCLTCL1chr22:19076881chr22:19178947ENST000003538912532449_46513971665.0RegionBinding site for the uncoating ATPase%2C involved in lattice disassembly
TgeneCLTCL1chr22:19076881chr22:19178947ENST000003538912532480_52313971665.0RegionNote=Flexible linker
TgeneCLTCL1chr22:19076881chr22:19178947ENST000003538912532524_164013971665.0RegionNote=Heavy chain arm
TgeneCLTCL1chr22:19076881chr22:19178947ENST000003538912532524_63413971665.0RegionNote=Distal segment
TgeneCLTCL1chr22:19076881chr22:19178947ENST000003538912532639_164013971665.0RegionNote=Proximal segment
TgeneCLTCL1chr22:19076881chr22:19178947ENST00000353891253268_10713971665.0RegionNote=WD40-like repeat 2
TgeneCLTCL1chr22:19076881chr22:19178947ENST000004279262634108_14913971710.6666666666667RegionNote=WD40-like repeat 3
TgeneCLTCL1chr22:19076881chr22:19178947ENST0000042792626341213_152213971710.6666666666667RegionInvolved in binding clathrin light chain
TgeneCLTCL1chr22:19076881chr22:19178947ENST000004279262634150_19513971710.6666666666667RegionNote=WD40-like repeat 4
TgeneCLTCL1chr22:19076881chr22:19178947ENST000004279262634196_25713971710.6666666666667RegionNote=WD40-like repeat 5
TgeneCLTCL1chr22:19076881chr22:19178947ENST00000427926263424_6713971710.6666666666667RegionNote=WD40-like repeat 1
TgeneCLTCL1chr22:19076881chr22:19178947ENST000004279262634258_30113971710.6666666666667RegionNote=WD40-like repeat 6
TgeneCLTCL1chr22:19076881chr22:19178947ENST0000042792626342_47913971710.6666666666667RegionNote=Globular terminal domain
TgeneCLTCL1chr22:19076881chr22:19178947ENST000004279262634302_33013971710.6666666666667RegionNote=WD40-like repeat 7
TgeneCLTCL1chr22:19076881chr22:19178947ENST000004279262634449_46513971710.6666666666667RegionBinding site for the uncoating ATPase%2C involved in lattice disassembly
TgeneCLTCL1chr22:19076881chr22:19178947ENST000004279262634480_52313971710.6666666666667RegionNote=Flexible linker
TgeneCLTCL1chr22:19076881chr22:19178947ENST000004279262634524_164013971710.6666666666667RegionNote=Heavy chain arm
TgeneCLTCL1chr22:19076881chr22:19178947ENST000004279262634524_63413971710.6666666666667RegionNote=Distal segment
TgeneCLTCL1chr22:19076881chr22:19178947ENST000004279262634639_164013971710.6666666666667RegionNote=Proximal segment
TgeneCLTCL1chr22:19076881chr22:19178947ENST00000427926263468_10713971710.6666666666667RegionNote=WD40-like repeat 2
TgeneCLTCL1chr22:19076881chr22:19263353ENST000002632000332_479141712.3333333333333RegionNote=Globular terminal domain
TgeneCLTCL1chr22:19076881chr22:19263353ENST000003538910322_479141665.0RegionNote=Globular terminal domain
TgeneCLTCL1chr22:19076881chr22:19263353ENST000004279260342_479141710.6666666666667RegionNote=Globular terminal domain
TgeneCLTCL1chr22:19076881chr22:19178947ENST0000026320025331128_126913971712.3333333333333RepeatNote=CHCR 5
TgeneCLTCL1chr22:19076881chr22:19178947ENST0000026320025331274_142013971712.3333333333333RepeatNote=CHCR 6
TgeneCLTCL1chr22:19076881chr22:19178947ENST000002632002533537_68313971712.3333333333333RepeatNote=CHCR 1
TgeneCLTCL1chr22:19076881chr22:19178947ENST000002632002533686_82813971712.3333333333333RepeatNote=CHCR 2
TgeneCLTCL1chr22:19076881chr22:19178947ENST000002632002533833_97213971712.3333333333333RepeatNote=CHCR 3
TgeneCLTCL1chr22:19076881chr22:19178947ENST000002632002533979_112413971712.3333333333333RepeatNote=CHCR 4
TgeneCLTCL1chr22:19076881chr22:19178947ENST0000035389125321128_126913971665.0RepeatNote=CHCR 5
TgeneCLTCL1chr22:19076881chr22:19178947ENST0000035389125321274_142013971665.0RepeatNote=CHCR 6
TgeneCLTCL1chr22:19076881chr22:19178947ENST000003538912532537_68313971665.0RepeatNote=CHCR 1
TgeneCLTCL1chr22:19076881chr22:19178947ENST000003538912532686_82813971665.0RepeatNote=CHCR 2
TgeneCLTCL1chr22:19076881chr22:19178947ENST000003538912532833_97213971665.0RepeatNote=CHCR 3
TgeneCLTCL1chr22:19076881chr22:19178947ENST000003538912532979_112413971665.0RepeatNote=CHCR 4
TgeneCLTCL1chr22:19076881chr22:19178947ENST0000042792626341128_126913971710.6666666666667RepeatNote=CHCR 5
TgeneCLTCL1chr22:19076881chr22:19178947ENST0000042792626341274_142013971710.6666666666667RepeatNote=CHCR 6
TgeneCLTCL1chr22:19076881chr22:19178947ENST000004279262634537_68313971710.6666666666667RepeatNote=CHCR 1
TgeneCLTCL1chr22:19076881chr22:19178947ENST000004279262634686_82813971710.6666666666667RepeatNote=CHCR 2
TgeneCLTCL1chr22:19076881chr22:19178947ENST000004279262634833_97213971710.6666666666667RepeatNote=CHCR 3
TgeneCLTCL1chr22:19076881chr22:19178947ENST000004279262634979_112413971710.6666666666667RepeatNote=CHCR 4


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Fusion Gene Sequence for DGCR2-CLTCL1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>22400_22400_1_DGCR2-CLTCL1_DGCR2_chr22_19076881_ENST00000545799_CLTCL1_chr22_19178947_ENST00000263200_length(transcript)=1652nt_BP=403nt
GCGCGCAGCTGGAGTCGGTGCCTGAGGTTGCAGCCGAGAGTGTGCGCCAGCCCGCGGCCCAGCCGAAGCTCTTTCCCGCCGCCTCTCCGC
GCCTCGCCCAGGTTCAGCTCCGCCTGACCCTCCGCTTGGCACGGTCCCCTGACCCTCAGTCCGGCCTGGTCCGGCCTTCCAGCCGCCCCG
GGGACGATGAACGGAGGATAAATGGTGCCCAAGGCAGACAGCGGCGCCTTCCTGCTGCTCTTCCTGCTCGTGCTCACTGTCACCGAGCCG
CTGCGGCCAGAGCTGCGGTGCAACCCTGGGCAGTTTGCGTGTCGCAGCGGCACCATCCAGTGCATCCCCCTCCCCTGGCAGTGTGACGGC
TGGGCGACTTGCGAGGATGAGAGCGACGAAGCCAACTGTCCAGGTTGCCAACGTCGAGCTCTGTTACAGAGCCCTGCAGTTCTATTTGGA
TTACAAACCACTGCTCATCAATGACCTGCTGCTGGTGCTTTCACCCCGGCTGGACCACACCTGGACAGTCAGTTTCTTTTCAAAGGCAGG
TCAGCTGCCCCTGGTGAAGCCTTACCTGCGGTCAGTCCAGAGCCACAACAACAAGAGTGTGAATGAGGCACTCAACCACCTGCTGACAGA
GGAGGAGGACTATCAGGGCTTAAGGGCATCTATCGATGCCTATGACAACTTTGACAACATCAGCCTGGCTCAGCAGCTGGAGAAGCATCA
GCTGATGGAGTTCAGGTGCATTGCGGCCTATCTGTACAAGGGCAATAACTGGTGGGCCCAGAGCGTGGAGCTCTGCAAGAAGGATCATCT
CTACAAGGATGCCATGCAGCATGCTGCAGAGTCGCGGGATGCTGAGCTGGCCCAGAAGTTGCTGCAGTGGTTCCTGGAGGAAGGCAAGAG
GGAGTGCTTCGCAGCTTGTCTCTTCACCTGCTATGACCTGCTTCGCCCAGACATGGTGCTTGAGCTGGCCTGGAGGCACAACCTCGTGGA
CTTGGCCATGCCCTACTTCATCCAGGTGATGAGGGAGTACCTGAGCAAGGTGGACAAACTGGATGCCTTGGAGAGTCTGCGCAAGCAAGA
GGAGCATGTGACAGAGCCTGCCCCTCTCGTGTTTGATTTTGATGGGCATGAATGAGACCCAGCTGATTGCACTAAGCCCTGCCGTGGGCC
CAGCCCCTGCCAGCTTCCCCTATGGATATGCCTCTGCTCCCAACTTCGCCAGCCTCCAATGTACAACTTCCGCGTGTAGTGGGCGTTGTC
ACCACCCACCCTACCTGCAGAGTTACTAACTTCTCCAAGGAGCATGTCACTCCAGCAGCACAGGGGACGCAATGGGAGGCAGGGACACCT
GGACAATATTTATTTTTGCTGAAACCCAATGACGGCAACCTCTGAGCCATCCCAGAGCCTGGGGAGGCCAGGGTAGAGGCTGACGGCGCA
AGACCAGCTTTAGCCGACAACAGAGACTGGACTGTGGGCCCTCCTGCTGGAGCCAGGCCTTCCTCCTGGGCGCCTCCGACTGGCTGGAGC
TGCCCCCTCCAGGCCAGTTTGAAGACTACATGAACACGTCTTGTTTGGAGGTACCGGACCTCATAAAAGGACTCTCAGCCTCTTGGCAAT

>22400_22400_1_DGCR2-CLTCL1_DGCR2_chr22_19076881_ENST00000545799_CLTCL1_chr22_19178947_ENST00000263200_length(amino acids)=292AA_BP=3
MSPSRCGQSCGATLGSLRVAAAPSSASPSPGSVTAGRLARMRATKPTVQVANVELCYRALQFYLDYKPLLINDLLLVLSPRLDHTWTVSF
FSKAGQLPLVKPYLRSVQSHNNKSVNEALNHLLTEEEDYQGLRASIDAYDNFDNISLAQQLEKHQLMEFRCIAAYLYKGNNWWAQSVELC
KKDHLYKDAMQHAAESRDAELAQKLLQWFLEEGKRECFAACLFTCYDLLRPDMVLELAWRHNLVDLAMPYFIQVMREYLSKVDKLDALES

--------------------------------------------------------------
>22400_22400_2_DGCR2-CLTCL1_DGCR2_chr22_19076881_ENST00000545799_CLTCL1_chr22_19178947_ENST00000353891_length(transcript)=1481nt_BP=403nt
GCGCGCAGCTGGAGTCGGTGCCTGAGGTTGCAGCCGAGAGTGTGCGCCAGCCCGCGGCCCAGCCGAAGCTCTTTCCCGCCGCCTCTCCGC
GCCTCGCCCAGGTTCAGCTCCGCCTGACCCTCCGCTTGGCACGGTCCCCTGACCCTCAGTCCGGCCTGGTCCGGCCTTCCAGCCGCCCCG
GGGACGATGAACGGAGGATAAATGGTGCCCAAGGCAGACAGCGGCGCCTTCCTGCTGCTCTTCCTGCTCGTGCTCACTGTCACCGAGCCG
CTGCGGCCAGAGCTGCGGTGCAACCCTGGGCAGTTTGCGTGTCGCAGCGGCACCATCCAGTGCATCCCCCTCCCCTGGCAGTGTGACGGC
TGGGCGACTTGCGAGGATGAGAGCGACGAAGCCAACTGTCCAGGTTGCCAACGTCGAGCTCTGTTACAGAGCCCTGCAGTTCTATTTGGA
TTACAAACCACTGCTCATCAATGACCTGCTGCTGGTGCTTTCACCCCGGCTGGACCACACCTGGACAGTCAGTTTCTTTTCAAAGGCAGG
TCAGCTGCCCCTGGTGAAGCCTTACCTGCGGTCAGTCCAGAGCCACAACAACAAGAGTGTGAATGAGGCACTCAACCACCTGCTGACAGA
GGAGGAGGACTATCAGGATGCCATGCAGCATGCTGCAGAGTCGCGGGATGCTGAGCTGGCCCAGAAGTTGCTGCAGTGGTTCCTGGAGGA
AGGCAAGAGGGAGTGCTTCGCAGCTTGTCTCTTCACCTGCTATGACCTGCTTCGCCCAGACATGGTGCTTGAGCTGGCCTGGAGGCACAA
CCTCGTGGACTTGGCCATGCCCTACTTCATCCAGGTGATGAGGGAGTACCTGAGCAAGGTGGACAAACTGGATGCCTTGGAGAGTCTGCG
CAAGCAAGAGGAGCATGTGACAGAGCCTGCCCCTCTCGTGTTTGATTTTGATGGGCATGAATGAGACCCAGCTGATTGCACTAAGCCCTG
CCGTGGGCCCAGCCCCTGCCAGCTTCCCCTATGGATATGCCTCTGCTCCCAACTTCGCCAGCCTCCAATGTACAACTTCCGCGTGTAGTG
GGCGTTGTCACCACCCACCCTACCTGCAGAGTTACTAACTTCTCCAAGGAGCATGTCACTCCAGCAGCACAGGGGACGCAATGGGAGGCA
GGGACACCTGGACAATATTTATTTTTGCTGAAACCCAATGACGGCAACCTCTGAGCCATCCCAGAGCCTGGGGAGGCCAGGGTAGAGGCT
GACGGCGCAAGACCAGCTTTAGCCGACAACAGAGACTGGACTGTGGGCCCTCCTGCTGGAGCCAGGCCTTCCTCCTGGGCGCCTCCGACT
GGCTGGAGCTGCCCCCTCCAGGCCAGTTTGAAGACTACATGAACACGTCTTGTTTGGAGGTACCGGACCTCATAAAAGGACTCTCAGCCT

>22400_22400_2_DGCR2-CLTCL1_DGCR2_chr22_19076881_ENST00000545799_CLTCL1_chr22_19178947_ENST00000353891_length(amino acids)=235AA_BP=3
MSPSRCGQSCGATLGSLRVAAAPSSASPSPGSVTAGRLARMRATKPTVQVANVELCYRALQFYLDYKPLLINDLLLVLSPRLDHTWTVSF
FSKAGQLPLVKPYLRSVQSHNNKSVNEALNHLLTEEEDYQDAMQHAAESRDAELAQKLLQWFLEEGKRECFAACLFTCYDLLRPDMVLEL

--------------------------------------------------------------
>22400_22400_3_DGCR2-CLTCL1_DGCR2_chr22_19076881_ENST00000545799_CLTCL1_chr22_19178947_ENST00000427926_length(transcript)=1649nt_BP=403nt
GCGCGCAGCTGGAGTCGGTGCCTGAGGTTGCAGCCGAGAGTGTGCGCCAGCCCGCGGCCCAGCCGAAGCTCTTTCCCGCCGCCTCTCCGC
GCCTCGCCCAGGTTCAGCTCCGCCTGACCCTCCGCTTGGCACGGTCCCCTGACCCTCAGTCCGGCCTGGTCCGGCCTTCCAGCCGCCCCG
GGGACGATGAACGGAGGATAAATGGTGCCCAAGGCAGACAGCGGCGCCTTCCTGCTGCTCTTCCTGCTCGTGCTCACTGTCACCGAGCCG
CTGCGGCCAGAGCTGCGGTGCAACCCTGGGCAGTTTGCGTGTCGCAGCGGCACCATCCAGTGCATCCCCCTCCCCTGGCAGTGTGACGGC
TGGGCGACTTGCGAGGATGAGAGCGACGAAGCCAACTGTCCAGGTTGCCAACGTCGAGCTCTGTTACAGAGCCCTGCAGTTCTATTTGGA
TTACAAACCACTGCTCATCAATGACCTGCTGCTGGTGCTTTCACCCCGGCTGGACCACACCTGGACAGTCAGTTTCTTTTCAAAGGCAGG
TCAGCTGCCCCTGGTGAAGCCTTACCTGCGGTCAGTCCAGAGCCACAACAACAAGAGTGTGAATGAGGCACTCAACCACCTGCTGACAGA
GGAGGAGGACTATCAGGGCTTAAGGGCATCTATCGATGCCTATGACAACTTTGACAACATCAGCCTGGCTCAGCAGCTGGAGAAGCATCA
GCTGATGGAGTTCAGGTGCATTGCGGCCTATCTGTACAAGGGCAATAACTGGTGGGCCCAGAGCGTGGAGCTCTGCAAGAAGGATCATCT
CTACAAGGATGCCATGCAGCATGCTGCAGAGTCGCGGGATGCTGAGCTGGCCCAGAAGTTGCTGCAGTGGTTCCTGGAGGAAGGCAAGAG
GGAGTGCTTCGCAGCTTGTCTCTTCACCTGCTATGACCTGCTTCGCCCAGACATGGTGCTTGAGCTGGCCTGGAGGCACAACCTCGTGGA
CTTGGCCATGCCCTACTTCATCCAGGTGATGAGGGAGTACCTGAGCAAGGTGGACAAACTGGATGCCTTGGAGAGTCTGCGCAAGCAAGA
GGAGCATGTGACAGAGCCTGCCCCTCTCGTGTTTGATTTTGATGGGCATGAATGAGACCCAGCTGATTGCACTAAGCCCTGCCGTGGGCC
CAGCCCCTGCCAGCTTCCCCTATGGATATGCCTCTGCTCCCAACTTCGCCAGCCTCCAATGTACAACTTCCGCGTGTAGTGGGCGTTGTC
ACCACCCACCCTACCTGCAGAGTTACTAACTTCTCCAAGGAGCATGTCACTCCAGCAGCACAGGGGACGCAATGGGAGGCAGGGACACCT
GGACAATATTTATTTTTGCTGAAACCCAATGACGGCAACCTCTGAGCCATCCCAGAGCCTGGGGAGGCCAGGGTAGAGGCTGACGGCGCA
AGACCAGCTTTAGCCGACAACAGAGACTGGACTGTGGGCCCTCCTGCTGGAGCCAGGCCTTCCTCCTGGGCGCCTCCGACTGGCTGGAGC
TGCCCCCTCCAGGCCAGTTTGAAGACTACATGAACACGTCTTGTTTGGAGGTACCGGACCTCATAAAAGGACTCTCAGCCTCTTGGCAAT

>22400_22400_3_DGCR2-CLTCL1_DGCR2_chr22_19076881_ENST00000545799_CLTCL1_chr22_19178947_ENST00000427926_length(amino acids)=292AA_BP=3
MSPSRCGQSCGATLGSLRVAAAPSSASPSPGSVTAGRLARMRATKPTVQVANVELCYRALQFYLDYKPLLINDLLLVLSPRLDHTWTVSF
FSKAGQLPLVKPYLRSVQSHNNKSVNEALNHLLTEEEDYQGLRASIDAYDNFDNISLAQQLEKHQLMEFRCIAAYLYKGNNWWAQSVELC
KKDHLYKDAMQHAAESRDAELAQKLLQWFLEEGKRECFAACLFTCYDLLRPDMVLELAWRHNLVDLAMPYFIQVMREYLSKVDKLDALES

--------------------------------------------------------------
>22400_22400_4_DGCR2-CLTCL1_DGCR2_chr22_19076881_ENST00000545799_CLTCL1_chr22_19263353_ENST00000263200_length(transcript)=5801nt_BP=403nt
GCGCGCAGCTGGAGTCGGTGCCTGAGGTTGCAGCCGAGAGTGTGCGCCAGCCCGCGGCCCAGCCGAAGCTCTTTCCCGCCGCCTCTCCGC
GCCTCGCCCAGGTTCAGCTCCGCCTGACCCTCCGCTTGGCACGGTCCCCTGACCCTCAGTCCGGCCTGGTCCGGCCTTCCAGCCGCCCCG
GGGACGATGAACGGAGGATAAATGGTGCCCAAGGCAGACAGCGGCGCCTTCCTGCTGCTCTTCCTGCTCGTGCTCACTGTCACCGAGCCG
CTGCGGCCAGAGCTGCGGTGCAACCCTGGGCAGTTTGCGTGTCGCAGCGGCACCATCCAGTGCATCCCCCTCCCCTGGCAGTGTGACGGC
TGGGCGACTTGCGAGGATGAGAGCGACGAAGCCAACTGTCCAGCTCCAAAACCTTGGAATTAATCCAGCTAACATTGGATTCAGCACACT
GACCATGGAATCTGACAAGTTCATATGTATCCGAGAGAAAGTTGGTGAGCAGGCACAGGTCACGATCATTGACATGAGTGACCCAATGGC
TCCGATCCGACGGCCTATCTCTGCAGAGAGTGCCATCATGAATCCAGCCTCTAAGGTGATAGCTCTGAAAGCTGGGAAGACACTTCAGAT
CTTTAATATTGAGATGAAGAGTAAAATGAAGGCTCATACTATGGCAGAAGAAGTGATTTTCTGGAAATGGGTTTCTGTGAACACTGTTGC
CTTGGTGACCGAGACCGCGGTCTACCACTGGAGCATGGAAGGTGACTCCCAGCCCATGAAGATGTTTGATAGACATACCAGTCTGGTGGG
CTGCCAGGTGATTCACTACCGGACTGATGAGTACCAGAAGTGGCTGCTGCTCGTAGGCATCTCGGCTCAGCAAAACCGTGTGGTTGGAGC
AATGCAGCTCTACTCTGTGGATAGGAAGGTTTCACAACCCATAGAAGGCCATGCTGCGGCTTTTGCAGAGTTCAAGATGGAGGGGAATGC
CAAGCCTGCCACCCTTTTCTGCTTTGCTGTACGTAATCCCACAGGAGGCAAGTTGCACATCATTGAAGTTGGACAGCCTGCAGCGGGAAA
CCAACCTTTTGTAAAGAAAGCAGTAGATGTGTTTTTTCCTCCAGAGGCACAGAATGATTTTCCAGTGGCTATGCAGATTGGAGCTAAACA
TGGTGTTATTTACTTGATCACAAAGTATGGCTATCTTCATCTGTACGACCTAGAGTCTGGCGTGTGCATCTGCATGAACCGTATTAGTGC
TGACACAATATTTGTCACTGCTCCACACAAACCAACCTCTGGAATTATTGGTGTCAACAAAAAGGGACAGGTACTGTCAGTTTGTGTTGA
GGAAGATAACATTGTGAATTATGCAACCAACGTGCTTCAGAATCCAGACCTTGGTCTGCGTTTGGCCGTTCGTAGTAACCTGGCTGGGGC
AGAGAAGTTGTTTGTGAGAAAATTCAATACCCTCTTTGCACAGGGCAGCTATGCTGAAGCCGCCAAAGTTGCAGCGTCTGCACCAAAGGG
AATCCTGCGTACCAGAGAGACGGTCCAGAAATTCCAGAGTATACCCGCTCAGTCTGGCCAGGCTTCTCCATTGCTGCAGTACTTCGGAAT
CCTGCTCGACCAGGGTCAGCTCAATAAACTTGAATCCTTAGAACTTTGCCATCTGGTTCTTCAGCAGGGGCGTAAGCAACTCCTAGAGAA
GTGGCTGAAAGAAGATAAGCTGGAGTGCTCAGAGGAGCTCGGAGACTTGGTCAAAACCACTGACCCCATGCTCGCTCTGAGTGTGTACCT
TCGGGCAAATGTGCCAAGCAAAGTGATCCAGTGTTTTGCAGAAACAGGCCAATTCCAGAAAATTGTGCTCTATGCCAAAAAGGTTGGGTA
CACCCCAGACTGGATCTTTCTGCTGAGGGGTGTAATGAAGATCAGTCCGGAACAGGGCCTGCAGTTTTCTCGAATGCTAGTGCAGGACGA
GGAGCCGCTGGCCAACATTAGCCAGATTGTGGACATTTTCATGGAAAACAGTTTAATTCAGCAGTGTACTTCCTTCTTATTGGATGCCTT
GAAGAATAATCGCCCAGCTGAGGGACTCCTGCAGACATGGCTGTTGGAGATGAACCTTGTTCATGCACCCCAGGTTGCAGATGCCATCCT
TGGAAATAAAATGTTTACTCATTACGACCGGGCCCACATTGCCCAGCTCTGTGAGAAGGCAGGCCTCCTGCAGCAAGCACTGGAGCACTA
CACCGACCTCTATGACATCAAGAGGGCTGTGGTCCACACTCACCTCCTCAATCCCGAGTGGCTTGTCAATTTCTTTGGCTCCTTATCGGT
GGAGGATTCTGTGGAGTGTCTGCATGCCATGCTGTCTGCTAACATCAGACAGAACCTTCAGCTGTGTGTGCAGGTGGCCTCTAAGTACCA
CGAGCAGCTGGGCACGCAGGCCCTGGTGGAGCTCTTTGAATCCTTCAAGAGTTACAAAGGCCTCTTCTACTTCCTGGGCTCAATCGTGAA
CTTCAGCCAAGACCCAGATGTGCATCTGAAATACATTCAGGCTGCCTGTAAGACAGGGCAGATCAAGGAGGTGGAGAGGATATGCCGAGA
GAGCAGCTGCTACAACCCAGAGCGTGTGAAGAACTTCCTGAAGGAGGCCAAGCTCACAGACCAGCTTCCCCTCATCATCGTGTGTGATCG
TTTTGGCTTTGTCCATGACCTTGTCCTATATTTATACCGCAACAACCTGCAGAGGTACATTGAGATCTACGTGCAGAAGGTCAACCCTAG
CCGGACCCCAGCTGTGATTGGAGGGCTGCTTGATGTGGATTGTTCTGAGGAAGTGATTAAACACTTAATCATGGCAGTGAGAGGACAGTT
CTCTACTGATGAGTTGGTGGCTGAAGTAGAAAAAAGAAATAGGCTCAAGCTGCTGCTTCCCTGGCTGGAGTCCCAGATTCAGGAAGGCTG
TGAGGAGCCTGCCACTCACAATGCACTGGCTAAAATCTACATCGACAGCAACAACAGCCCCGAGTGCTTCCTGAGAGAGAATGCCTACTA
TGACAGCAGCGTGGTGGGCCGCTACTGTGAGAAGCGAGACCCCCATCTGGCCTGTGTTGCCTATGAGCGGGGGCAGTGTGACCTTGAGCT
CATCAAGGTGTGCAATGAGAATTCTCTGTTCAAAAGCGAGGCCCGCTACCTGGTATGCAGAAAGGATCCGGAGCTCTGGGCTCACGTCCT
TGAGGAGACCAACCCATCCAGGAGACAGCTAATTGACCAGGTGGTACAGACAGCATTGTCAGAAACACGGGATCCTGAAGAGATTTCGGT
CACTGTCAAAGCCTTTATGACAGCCGACCTGCCTAATGAACTGATTGAACTGCTGGAGAAGATAGTTCTGGATAACTCTGTCTTCAGCGA
GCACAGGAATCTACAGAATCTGTTGATCCTGACTGCCATCAAGGCAGACCGCACACGGGTCATGGAGTACATCAGCCGCCTGGACAACTA
TGACGCACTGGACATCGCGAGCATCGCTGTCAGCAGCGCACTGTATGAGGAGGCCTTCACCGTTTTCCACAAGTTTGATATGAATGCCTC
AGCAATCCAGGTCCTGATCGAGCACATTGGAAACCTGGACCGGGCATATGAGTTTGCGGAGAGATGCAATGAGCCTGCTGTGTGGAGTCA
GCTGGCCCAAGCCCAGCTCCAGAAAGATTTGGTGAAGGAAGCCATCAACTCCTATATCAGAGGGGACGACCCTTCCTCTTACCTGGAAGT
TGTTCAGTCAGCCAGCAGGAGCAACAACTGGGAGGATCTAGTTAAATTTCTGCAGATGGCCAGGAAAAAGGGCCGTGAGTCCTATATAGA
GACTGAACTTATTTTTGCCTTGGCTAAAACCAGCCGTGTTTCTGAGCTAGAAGATTTTATTAATGGACCCAACAATGCCCACATCCAGCA
GGTTGGAGACCGCTGTTACGAGGAGGGAATGTACGAGGCTGCCAAGCTGCTCTATAGCAATGTTTCTAACTTTGCCCGCCTGGCTTCCAC
CTTGGTTCACCTCGGTGAGTATCAGGCAGCAGTGGACAACAGCCGCAAGGCCAGCAGCACCCGGACGTGGAAGGAGGTGTGCTTTGCCTG
CATGGATGGACAAGAGTTCCGCTTCGCACAGCTGTGTGGTCTTCACATCGTCATTCATGCAGATGAGCTGGAGGAGCTGATGTGCTATTA
CCAGGATCGTGGCTACTTTGAGGAGCTGATCTTGCTGTTGGAAGCGGCCCTGGGCCTGGAGCGGGCCCACATGGGCATGTTCACTGAGCT
GGCCATCCTCTACTCCAAATTCAAGCCACAGAAGATGCTGGAGCATCTGGAGCTTTTCTGGTCCCGTGTCAACATCCCAAAGGTGCTGAG
GGCTGCAGAGCAGGCACACCTGTGGGCTGAGCTGGTGTTCCTCTATGACAAGTACGAGGAGTATGACAATGCTGTGCTCACCATGATGAG
CCACCCCACTGAGGCCTGGAAGGAGGGTCAGTTCAAGGACATCATTACCAAGGTTGCCAACGTCGAGCTCTGTTACAGAGCCCTGCAGTT
CTATTTGGATTACAAACCACTGCTCATCAATGACCTGCTGCTGGTGCTTTCACCCCGGCTGGACCACACCTGGACAGTCAGTTTCTTTTC
AAAGGCAGGTCAGCTGCCCCTGGTGAAGCCTTACCTGCGGTCAGTCCAGAGCCACAACAACAAGAGTGTGAATGAGGCACTCAACCACCT
GCTGACAGAGGAGGAGGACTATCAGGGCTTAAGGGCATCTATCGATGCCTATGACAACTTTGACAACATCAGCCTGGCTCAGCAGCTGGA
GAAGCATCAGCTGATGGAGTTCAGGTGCATTGCGGCCTATCTGTACAAGGGCAATAACTGGTGGGCCCAGAGCGTGGAGCTCTGCAAGAA
GGATCATCTCTACAAGGATGCCATGCAGCATGCTGCAGAGTCGCGGGATGCTGAGCTGGCCCAGAAGTTGCTGCAGTGGTTCCTGGAGGA
AGGCAAGAGGGAGTGCTTCGCAGCTTGTCTCTTCACCTGCTATGACCTGCTTCGCCCAGACATGGTGCTTGAGCTGGCCTGGAGGCACAA
CCTCGTGGACTTGGCCATGCCCTACTTCATCCAGGTGATGAGGGAGTACCTGAGCAAGGTGGACAAACTGGATGCCTTGGAGAGTCTGCG
CAAGCAAGAGGAGCATGTGACAGAGCCTGCCCCTCTCGTGTTTGATTTTGATGGGCATGAATGAGACCCAGCTGATTGCACTAAGCCCTG
CCGTGGGCCCAGCCCCTGCCAGCTTCCCCTATGGATATGCCTCTGCTCCCAACTTCGCCAGCCTCCAATGTACAACTTCCGCGTGTAGTG
GGCGTTGTCACCACCCACCCTACCTGCAGAGTTACTAACTTCTCCAAGGAGCATGTCACTCCAGCAGCACAGGGGACGCAATGGGAGGCA
GGGACACCTGGACAATATTTATTTTTGCTGAAACCCAATGACGGCAACCTCTGAGCCATCCCAGAGCCTGGGGAGGCCAGGGTAGAGGCT
GACGGCGCAAGACCAGCTTTAGCCGACAACAGAGACTGGACTGTGGGCCCTCCTGCTGGAGCCAGGCCTTCCTCCTGGGCGCCTCCGACT
GGCTGGAGCTGCCCCCTCCAGGCCAGTTTGAAGACTACATGAACACGTCTTGTTTGGAGGTACCGGACCTCATAAAAGGACTCTCAGCCT

>22400_22400_4_DGCR2-CLTCL1_DGCR2_chr22_19076881_ENST00000545799_CLTCL1_chr22_19263353_ENST00000263200_length(amino acids)=1675AA_BP=3
MSPSRCGQSCGATLGSLRVAAAPSSASPSPGSVTAGRLARMRATKPTVQLQNLGINPANIGFSTLTMESDKFICIREKVGEQAQVTIIDM
SDPMAPIRRPISAESAIMNPASKVIALKAGKTLQIFNIEMKSKMKAHTMAEEVIFWKWVSVNTVALVTETAVYHWSMEGDSQPMKMFDRH
TSLVGCQVIHYRTDEYQKWLLLVGISAQQNRVVGAMQLYSVDRKVSQPIEGHAAAFAEFKMEGNAKPATLFCFAVRNPTGGKLHIIEVGQ
PAAGNQPFVKKAVDVFFPPEAQNDFPVAMQIGAKHGVIYLITKYGYLHLYDLESGVCICMNRISADTIFVTAPHKPTSGIIGVNKKGQVL
SVCVEEDNIVNYATNVLQNPDLGLRLAVRSNLAGAEKLFVRKFNTLFAQGSYAEAAKVAASAPKGILRTRETVQKFQSIPAQSGQASPLL
QYFGILLDQGQLNKLESLELCHLVLQQGRKQLLEKWLKEDKLECSEELGDLVKTTDPMLALSVYLRANVPSKVIQCFAETGQFQKIVLYA
KKVGYTPDWIFLLRGVMKISPEQGLQFSRMLVQDEEPLANISQIVDIFMENSLIQQCTSFLLDALKNNRPAEGLLQTWLLEMNLVHAPQV
ADAILGNKMFTHYDRAHIAQLCEKAGLLQQALEHYTDLYDIKRAVVHTHLLNPEWLVNFFGSLSVEDSVECLHAMLSANIRQNLQLCVQV
ASKYHEQLGTQALVELFESFKSYKGLFYFLGSIVNFSQDPDVHLKYIQAACKTGQIKEVERICRESSCYNPERVKNFLKEAKLTDQLPLI
IVCDRFGFVHDLVLYLYRNNLQRYIEIYVQKVNPSRTPAVIGGLLDVDCSEEVIKHLIMAVRGQFSTDELVAEVEKRNRLKLLLPWLESQ
IQEGCEEPATHNALAKIYIDSNNSPECFLRENAYYDSSVVGRYCEKRDPHLACVAYERGQCDLELIKVCNENSLFKSEARYLVCRKDPEL
WAHVLEETNPSRRQLIDQVVQTALSETRDPEEISVTVKAFMTADLPNELIELLEKIVLDNSVFSEHRNLQNLLILTAIKADRTRVMEYIS
RLDNYDALDIASIAVSSALYEEAFTVFHKFDMNASAIQVLIEHIGNLDRAYEFAERCNEPAVWSQLAQAQLQKDLVKEAINSYIRGDDPS
SYLEVVQSASRSNNWEDLVKFLQMARKKGRESYIETELIFALAKTSRVSELEDFINGPNNAHIQQVGDRCYEEGMYEAAKLLYSNVSNFA
RLASTLVHLGEYQAAVDNSRKASSTRTWKEVCFACMDGQEFRFAQLCGLHIVIHADELEELMCYYQDRGYFEELILLLEAALGLERAHMG
MFTELAILYSKFKPQKMLEHLELFWSRVNIPKVLRAAEQAHLWAELVFLYDKYEEYDNAVLTMMSHPTEAWKEGQFKDIITKVANVELCY
RALQFYLDYKPLLINDLLLVLSPRLDHTWTVSFFSKAGQLPLVKPYLRSVQSHNNKSVNEALNHLLTEEEDYQGLRASIDAYDNFDNISL
AQQLEKHQLMEFRCIAAYLYKGNNWWAQSVELCKKDHLYKDAMQHAAESRDAELAQKLLQWFLEEGKRECFAACLFTCYDLLRPDMVLEL

--------------------------------------------------------------
>22400_22400_5_DGCR2-CLTCL1_DGCR2_chr22_19076881_ENST00000545799_CLTCL1_chr22_19263353_ENST00000353891_length(transcript)=5630nt_BP=403nt
GCGCGCAGCTGGAGTCGGTGCCTGAGGTTGCAGCCGAGAGTGTGCGCCAGCCCGCGGCCCAGCCGAAGCTCTTTCCCGCCGCCTCTCCGC
GCCTCGCCCAGGTTCAGCTCCGCCTGACCCTCCGCTTGGCACGGTCCCCTGACCCTCAGTCCGGCCTGGTCCGGCCTTCCAGCCGCCCCG
GGGACGATGAACGGAGGATAAATGGTGCCCAAGGCAGACAGCGGCGCCTTCCTGCTGCTCTTCCTGCTCGTGCTCACTGTCACCGAGCCG
CTGCGGCCAGAGCTGCGGTGCAACCCTGGGCAGTTTGCGTGTCGCAGCGGCACCATCCAGTGCATCCCCCTCCCCTGGCAGTGTGACGGC
TGGGCGACTTGCGAGGATGAGAGCGACGAAGCCAACTGTCCAGCTCCAAAACCTTGGAATTAATCCAGCTAACATTGGATTCAGCACACT
GACCATGGAATCTGACAAGTTCATATGTATCCGAGAGAAAGTTGGTGAGCAGGCACAGGTCACGATCATTGACATGAGTGACCCAATGGC
TCCGATCCGACGGCCTATCTCTGCAGAGAGTGCCATCATGAATCCAGCCTCTAAGGTGATAGCTCTGAAAGCTGGGAAGACACTTCAGAT
CTTTAATATTGAGATGAAGAGTAAAATGAAGGCTCATACTATGGCAGAAGAAGTGATTTTCTGGAAATGGGTTTCTGTGAACACTGTTGC
CTTGGTGACCGAGACCGCGGTCTACCACTGGAGCATGGAAGGTGACTCCCAGCCCATGAAGATGTTTGATAGACATACCAGTCTGGTGGG
CTGCCAGGTGATTCACTACCGGACTGATGAGTACCAGAAGTGGCTGCTGCTCGTAGGCATCTCGGCTCAGCAAAACCGTGTGGTTGGAGC
AATGCAGCTCTACTCTGTGGATAGGAAGGTTTCACAACCCATAGAAGGCCATGCTGCGGCTTTTGCAGAGTTCAAGATGGAGGGGAATGC
CAAGCCTGCCACCCTTTTCTGCTTTGCTGTACGTAATCCCACAGGAGGCAAGTTGCACATCATTGAAGTTGGACAGCCTGCAGCGGGAAA
CCAACCTTTTGTAAAGAAAGCAGTAGATGTGTTTTTTCCTCCAGAGGCACAGAATGATTTTCCAGTGGCTATGCAGATTGGAGCTAAACA
TGGTGTTATTTACTTGATCACAAAGTATGGCTATCTTCATCTGTACGACCTAGAGTCTGGCGTGTGCATCTGCATGAACCGTATTAGTGC
TGACACAATATTTGTCACTGCTCCACACAAACCAACCTCTGGAATTATTGGTGTCAACAAAAAGGGACAGGTACTGTCAGTTTGTGTTGA
GGAAGATAACATTGTGAATTATGCAACCAACGTGCTTCAGAATCCAGACCTTGGTCTGCGTTTGGCCGTTCGTAGTAACCTGGCTGGGGC
AGAGAAGTTGTTTGTGAGAAAATTCAATACCCTCTTTGCACAGGGCAGCTATGCTGAAGCCGCCAAAGTTGCAGCGTCTGCACCAAAGGG
AATCCTGCGTACCAGAGAGACGGTCCAGAAATTCCAGAGTATACCCGCTCAGTCTGGCCAGGCTTCTCCATTGCTGCAGTACTTCGGAAT
CCTGCTCGACCAGGGTCAGCTCAATAAACTTGAATCCTTAGAACTTTGCCATCTGGTTCTTCAGCAGGGGCGTAAGCAACTCCTAGAGAA
GTGGCTGAAAGAAGATAAGCTGGAGTGCTCAGAGGAGCTCGGAGACTTGGTCAAAACCACTGACCCCATGCTCGCTCTGAGTGTGTACCT
TCGGGCAAATGTGCCAAGCAAAGTGATCCAGTGTTTTGCAGAAACAGGCCAATTCCAGAAAATTGTGCTCTATGCCAAAAAGGTTGGGTA
CACCCCAGACTGGATCTTTCTGCTGAGGGGTGTAATGAAGATCAGTCCGGAACAGGGCCTGCAGTTTTCTCGAATGCTAGTGCAGGACGA
GGAGCCGCTGGCCAACATTAGCCAGATTGTGGACATTTTCATGGAAAACAGTTTAATTCAGCAGTGTACTTCCTTCTTATTGGATGCCTT
GAAGAATAATCGCCCAGCTGAGGGACTCCTGCAGACATGGCTGTTGGAGATGAACCTTGTTCATGCACCCCAGGTTGCAGATGCCATCCT
TGGAAATAAAATGTTTACTCATTACGACCGGGCCCACATTGCCCAGCTCTGTGAGAAGGCAGGCCTCCTGCAGCAAGCACTGGAGCACTA
CACCGACCTCTATGACATCAAGAGGGCTGTGGTCCACACTCACCTCCTCAATCCCGAGTGGCTTGTCAATTTCTTTGGCTCCTTATCGGT
GGAGGATTCTGTGGAGTGTCTGCATGCCATGCTGTCTGCTAACATCAGACAGAACCTTCAGCTGTGTGTGCAGGTGGCCTCTAAGTACCA
CGAGCAGCTGGGCACGCAGGCCCTGGTGGAGCTCTTTGAATCCTTCAAGAGTTACAAAGGCCTCTTCTACTTCCTGGGCTCAATCGTGAA
CTTCAGCCAAGACCCAGATGTGCATCTGAAATACATTCAGGCTGCCTGTAAGACAGGGCAGATCAAGGAGGTGGAGAGGATATGCCGAGA
GAGCAGCTGCTACAACCCAGAGCGTGTGAAGAACTTCCTGAAGGAGGCCAAGCTCACAGACCAGCTTCCCCTCATCATCGTGTGTGATCG
TTTTGGCTTTGTCCATGACCTTGTCCTATATTTATACCGCAACAACCTGCAGAGGTACATTGAGATCTACGTGCAGAAGGTCAACCCTAG
CCGGACCCCAGCTGTGATTGGAGGGCTGCTTGATGTGGATTGTTCTGAGGAAGTGATTAAACACTTAATCATGGCAGTGAGAGGACAGTT
CTCTACTGATGAGTTGGTGGCTGAAGTAGAAAAAAGAAATAGGCTCAAGCTGCTGCTTCCCTGGCTGGAGTCCCAGATTCAGGAAGGCTG
TGAGGAGCCTGCCACTCACAATGCACTGGCTAAAATCTACATCGACAGCAACAACAGCCCCGAGTGCTTCCTGAGAGAGAATGCCTACTA
TGACAGCAGCGTGGTGGGCCGCTACTGTGAGAAGCGAGACCCCCATCTGGCCTGTGTTGCCTATGAGCGGGGGCAGTGTGACCTTGAGCT
CATCAAGGTGTGCAATGAGAATTCTCTGTTCAAAAGCGAGGCCCGCTACCTGGTATGCAGAAAGGATCCGGAGCTCTGGGCTCACGTCCT
TGAGGAGACCAACCCATCCAGGAGACAGCTAATTGACCAGGTGGTACAGACAGCATTGTCAGAAACACGGGATCCTGAAGAGATTTCGGT
CACTGTCAAAGCCTTTATGACAGCCGACCTGCCTAATGAACTGATTGAACTGCTGGAGAAGATAGTTCTGGATAACTCTGTCTTCAGCGA
GCACAGGAATCTACAGAATCTGTTGATCCTGACTGCCATCAAGGCAGACCGCACACGGGTCATGGAGTACATCAGCCGCCTGGACAACTA
TGACGCACTGGACATCGCGAGCATCGCTGTCAGCAGCGCACTGTATGAGGAGGCCTTCACCGTTTTCCACAAGTTTGATATGAATGCCTC
AGCAATCCAGGTCCTGATCGAGCACATTGGAAACCTGGACCGGGCATATGAGTTTGCGGAGAGATGCAATGAGCCTGCTGTGTGGAGTCA
GCTGGCCCAAGCCCAGCTCCAGAAAGATTTGGTGAAGGAAGCCATCAACTCCTATATCAGAGGGGACGACCCTTCCTCTTACCTGGAAGT
TGTTCAGTCAGCCAGCAGGAGCAACAACTGGGAGGATCTAGTTAAATTTCTGCAGATGGCCAGGAAAAAGGGCCGTGAGTCCTATATAGA
GACTGAACTTATTTTTGCCTTGGCTAAAACCAGCCGTGTTTCTGAGCTAGAAGATTTTATTAATGGACCCAACAATGCCCACATCCAGCA
GGTTGGAGACCGCTGTTACGAGGAGGGAATGTACGAGGCTGCCAAGCTGCTCTATAGCAATGTTTCTAACTTTGCCCGCCTGGCTTCCAC
CTTGGTTCACCTCGGTGAGTATCAGGCAGCAGTGGACAACAGCCGCAAGGCCAGCAGCACCCGGACGTGGAAGGAGGTGTGCTTTGCCTG
CATGGATGGACAAGAGTTCCGCTTCGCACAGCTGTGTGGTCTTCACATCGTCATTCATGCAGATGAGCTGGAGGAGCTGATGTGCTATTA
CCAGGATCGTGGCTACTTTGAGGAGCTGATCTTGCTGTTGGAAGCGGCCCTGGGCCTGGAGCGGGCCCACATGGGCATGTTCACTGAGCT
GGCCATCCTCTACTCCAAATTCAAGCCACAGAAGATGCTGGAGCATCTGGAGCTTTTCTGGTCCCGTGTCAACATCCCAAAGGTGCTGAG
GGCTGCAGAGCAGGCACACCTGTGGGCTGAGCTGGTGTTCCTCTATGACAAGTACGAGGAGTATGACAATGCTGTGCTCACCATGATGAG
CCACCCCACTGAGGCCTGGAAGGAGGGTCAGTTCAAGGACATCATTACCAAGGTTGCCAACGTCGAGCTCTGTTACAGAGCCCTGCAGTT
CTATTTGGATTACAAACCACTGCTCATCAATGACCTGCTGCTGGTGCTTTCACCCCGGCTGGACCACACCTGGACAGTCAGTTTCTTTTC
AAAGGCAGGTCAGCTGCCCCTGGTGAAGCCTTACCTGCGGTCAGTCCAGAGCCACAACAACAAGAGTGTGAATGAGGCACTCAACCACCT
GCTGACAGAGGAGGAGGACTATCAGGATGCCATGCAGCATGCTGCAGAGTCGCGGGATGCTGAGCTGGCCCAGAAGTTGCTGCAGTGGTT
CCTGGAGGAAGGCAAGAGGGAGTGCTTCGCAGCTTGTCTCTTCACCTGCTATGACCTGCTTCGCCCAGACATGGTGCTTGAGCTGGCCTG
GAGGCACAACCTCGTGGACTTGGCCATGCCCTACTTCATCCAGGTGATGAGGGAGTACCTGAGCAAGGTGGACAAACTGGATGCCTTGGA
GAGTCTGCGCAAGCAAGAGGAGCATGTGACAGAGCCTGCCCCTCTCGTGTTTGATTTTGATGGGCATGAATGAGACCCAGCTGATTGCAC
TAAGCCCTGCCGTGGGCCCAGCCCCTGCCAGCTTCCCCTATGGATATGCCTCTGCTCCCAACTTCGCCAGCCTCCAATGTACAACTTCCG
CGTGTAGTGGGCGTTGTCACCACCCACCCTACCTGCAGAGTTACTAACTTCTCCAAGGAGCATGTCACTCCAGCAGCACAGGGGACGCAA
TGGGAGGCAGGGACACCTGGACAATATTTATTTTTGCTGAAACCCAATGACGGCAACCTCTGAGCCATCCCAGAGCCTGGGGAGGCCAGG
GTAGAGGCTGACGGCGCAAGACCAGCTTTAGCCGACAACAGAGACTGGACTGTGGGCCCTCCTGCTGGAGCCAGGCCTTCCTCCTGGGCG
CCTCCGACTGGCTGGAGCTGCCCCCTCCAGGCCAGTTTGAAGACTACATGAACACGTCTTGTTTGGAGGTACCGGACCTCATAAAAGGAC

>22400_22400_5_DGCR2-CLTCL1_DGCR2_chr22_19076881_ENST00000545799_CLTCL1_chr22_19263353_ENST00000353891_length(amino acids)=1618AA_BP=3
MSPSRCGQSCGATLGSLRVAAAPSSASPSPGSVTAGRLARMRATKPTVQLQNLGINPANIGFSTLTMESDKFICIREKVGEQAQVTIIDM
SDPMAPIRRPISAESAIMNPASKVIALKAGKTLQIFNIEMKSKMKAHTMAEEVIFWKWVSVNTVALVTETAVYHWSMEGDSQPMKMFDRH
TSLVGCQVIHYRTDEYQKWLLLVGISAQQNRVVGAMQLYSVDRKVSQPIEGHAAAFAEFKMEGNAKPATLFCFAVRNPTGGKLHIIEVGQ
PAAGNQPFVKKAVDVFFPPEAQNDFPVAMQIGAKHGVIYLITKYGYLHLYDLESGVCICMNRISADTIFVTAPHKPTSGIIGVNKKGQVL
SVCVEEDNIVNYATNVLQNPDLGLRLAVRSNLAGAEKLFVRKFNTLFAQGSYAEAAKVAASAPKGILRTRETVQKFQSIPAQSGQASPLL
QYFGILLDQGQLNKLESLELCHLVLQQGRKQLLEKWLKEDKLECSEELGDLVKTTDPMLALSVYLRANVPSKVIQCFAETGQFQKIVLYA
KKVGYTPDWIFLLRGVMKISPEQGLQFSRMLVQDEEPLANISQIVDIFMENSLIQQCTSFLLDALKNNRPAEGLLQTWLLEMNLVHAPQV
ADAILGNKMFTHYDRAHIAQLCEKAGLLQQALEHYTDLYDIKRAVVHTHLLNPEWLVNFFGSLSVEDSVECLHAMLSANIRQNLQLCVQV
ASKYHEQLGTQALVELFESFKSYKGLFYFLGSIVNFSQDPDVHLKYIQAACKTGQIKEVERICRESSCYNPERVKNFLKEAKLTDQLPLI
IVCDRFGFVHDLVLYLYRNNLQRYIEIYVQKVNPSRTPAVIGGLLDVDCSEEVIKHLIMAVRGQFSTDELVAEVEKRNRLKLLLPWLESQ
IQEGCEEPATHNALAKIYIDSNNSPECFLRENAYYDSSVVGRYCEKRDPHLACVAYERGQCDLELIKVCNENSLFKSEARYLVCRKDPEL
WAHVLEETNPSRRQLIDQVVQTALSETRDPEEISVTVKAFMTADLPNELIELLEKIVLDNSVFSEHRNLQNLLILTAIKADRTRVMEYIS
RLDNYDALDIASIAVSSALYEEAFTVFHKFDMNASAIQVLIEHIGNLDRAYEFAERCNEPAVWSQLAQAQLQKDLVKEAINSYIRGDDPS
SYLEVVQSASRSNNWEDLVKFLQMARKKGRESYIETELIFALAKTSRVSELEDFINGPNNAHIQQVGDRCYEEGMYEAAKLLYSNVSNFA
RLASTLVHLGEYQAAVDNSRKASSTRTWKEVCFACMDGQEFRFAQLCGLHIVIHADELEELMCYYQDRGYFEELILLLEAALGLERAHMG
MFTELAILYSKFKPQKMLEHLELFWSRVNIPKVLRAAEQAHLWAELVFLYDKYEEYDNAVLTMMSHPTEAWKEGQFKDIITKVANVELCY
RALQFYLDYKPLLINDLLLVLSPRLDHTWTVSFFSKAGQLPLVKPYLRSVQSHNNKSVNEALNHLLTEEEDYQDAMQHAAESRDAELAQK

--------------------------------------------------------------
>22400_22400_6_DGCR2-CLTCL1_DGCR2_chr22_19076881_ENST00000545799_CLTCL1_chr22_19263353_ENST00000427926_length(transcript)=5798nt_BP=403nt
GCGCGCAGCTGGAGTCGGTGCCTGAGGTTGCAGCCGAGAGTGTGCGCCAGCCCGCGGCCCAGCCGAAGCTCTTTCCCGCCGCCTCTCCGC
GCCTCGCCCAGGTTCAGCTCCGCCTGACCCTCCGCTTGGCACGGTCCCCTGACCCTCAGTCCGGCCTGGTCCGGCCTTCCAGCCGCCCCG
GGGACGATGAACGGAGGATAAATGGTGCCCAAGGCAGACAGCGGCGCCTTCCTGCTGCTCTTCCTGCTCGTGCTCACTGTCACCGAGCCG
CTGCGGCCAGAGCTGCGGTGCAACCCTGGGCAGTTTGCGTGTCGCAGCGGCACCATCCAGTGCATCCCCCTCCCCTGGCAGTGTGACGGC
TGGGCGACTTGCGAGGATGAGAGCGACGAAGCCAACTGTCCAGCTCCAAAACCTTGGAATTAATCCAGCTAACATTGGATTCAGCACACT
GACCATGGAATCTGACAAGTTCATATGTATCCGAGAGAAAGTTGGTGAGCAGGCACAGGTCACGATCATTGACATGAGTGACCCAATGGC
TCCGATCCGACGGCCTATCTCTGCAGAGAGTGCCATCATGAATCCAGCCTCTAAGGTGATAGCTCTGAAAGCTGGGAAGACACTTCAGAT
CTTTAATATTGAGATGAAGAGTAAAATGAAGGCTCATACTATGGCAGAAGAAGTGATTTTCTGGAAATGGGTTTCTGTGAACACTGTTGC
CTTGGTGACCGAGACCGCGGTCTACCACTGGAGCATGGAAGGTGACTCCCAGCCCATGAAGATGTTTGATAGACATACCAGTCTGGTGGG
CTGCCAGGTGATTCACTACCGGACTGATGAGTACCAGAAGTGGCTGCTGCTCGTAGGCATCTCGGCTCAGCAAAACCGTGTGGTTGGAGC
AATGCAGCTCTACTCTGTGGATAGGAAGGTTTCACAACCCATAGAAGGCCATGCTGCGGCTTTTGCAGAGTTCAAGATGGAGGGGAATGC
CAAGCCTGCCACCCTTTTCTGCTTTGCTGTACGTAATCCCACAGGAGGCAAGTTGCACATCATTGAAGTTGGACAGCCTGCAGCGGGAAA
CCAACCTTTTGTAAAGAAAGCAGTAGATGTGTTTTTTCCTCCAGAGGCACAGAATGATTTTCCAGTGGCTATGCAGATTGGAGCTAAACA
TGGTGTTATTTACTTGATCACAAAGTATGGCTATCTTCATCTGTACGACCTAGAGTCTGGCGTGTGCATCTGCATGAACCGTATTAGTGC
TGACACAATATTTGTCACTGCTCCACACAAACCAACCTCTGGAATTATTGGTGTCAACAAAAAGGGACAGGTACTGTCAGTTTGTGTTGA
GGAAGATAACATTGTGAATTATGCAACCAACGTGCTTCAGAATCCAGACCTTGGTCTGCGTTTGGCCGTTCGTAGTAACCTGGCTGGGGC
AGAGAAGTTGTTTGTGAGAAAATTCAATACCCTCTTTGCACAGGGCAGCTATGCTGAAGCCGCCAAAGTTGCAGCGTCTGCACCAAAGGG
AATCCTGCGTACCAGAGAGACGGTCCAGAAATTCCAGAGTATACCCGCTCAGTCTGGCCAGGCTTCTCCATTGCTGCAGTACTTCGGAAT
CCTGCTCGACCAGGGTCAGCTCAATAAACTTGAATCCTTAGAACTTTGCCATCTGGTTCTTCAGCAGGGGCGTAAGCAACTCCTAGAGAA
GTGGCTGAAAGAAGATAAGCTGGAGTGCTCAGAGGAGCTCGGAGACTTGGTCAAAACCACTGACCCCATGCTCGCTCTGAGTGTGTACCT
TCGGGCAAATGTGCCAAGCAAAGTGATCCAGTGTTTTGCAGAAACAGGCCAATTCCAGAAAATTGTGCTCTATGCCAAAAAGGTTGGGTA
CACCCCAGACTGGATCTTTCTGCTGAGGGGTGTAATGAAGATCAGTCCGGAACAGGGCCTGCAGTTTTCTCGAATGCTAGTGCAGGACGA
GGAGCCGCTGGCCAACATTAGCCAGATTGTGGACATTTTCATGGAAAACAGTTTAATTCAGCAGTGTACTTCCTTCTTATTGGATGCCTT
GAAGAATAATCGCCCAGCTGAGGGACTCCTGCAGACATGGCTGTTGGAGATGAACCTTGTTCATGCACCCCAGGTTGCAGATGCCATCCT
TGGAAATAAAATGTTTACTCATTACGACCGGGCCCACATTGCCCAGCTCTGTGAGAAGGCAGGCCTCCTGCAGCAAGCACTGGAGCACTA
CACCGACCTCTATGACATCAAGAGGGCTGTGGTCCACACTCACCTCCTCAATCCCGAGTGGCTTGTCAATTTCTTTGGCTCCTTATCGGT
GGAGGATTCTGTGGAGTGTCTGCATGCCATGCTGTCTGCTAACATCAGACAGAACCTTCAGCTGTGTGTGCAGGTGGCCTCTAAGTACCA
CGAGCAGCTGGGCACGCAGGCCCTGGTGGAGCTCTTTGAATCCTTCAAGAGTTACAAAGGCCTCTTCTACTTCCTGGGCTCAATCGTGAA
CTTCAGCCAAGACCCAGATGTGCATCTGAAATACATTCAGGCTGCCTGTAAGACAGGGCAGATCAAGGAGGTGGAGAGGATATGCCGAGA
GAGCAGCTGCTACAACCCAGAGCGTGTGAAGAACTTCCTGAAGGAGGCCAAGCTCACAGACCAGCTTCCCCTCATCATCGTGTGTGATCG
TTTTGGCTTTGTCCATGACCTTGTCCTATATTTATACCGCAACAACCTGCAGAGGTACATTGAGATCTACGTGCAGAAGGTCAACCCTAG
CCGGACCCCAGCTGTGATTGGAGGGCTGCTTGATGTGGATTGTTCTGAGGAAGTGATTAAACACTTAATCATGGCAGTGAGAGGACAGTT
CTCTACTGATGAGTTGGTGGCTGAAGTAGAAAAAAGAAATAGGCTCAAGCTGCTGCTTCCCTGGCTGGAGTCCCAGATTCAGGAAGGCTG
TGAGGAGCCTGCCACTCACAATGCACTGGCTAAAATCTACATCGACAGCAACAACAGCCCCGAGTGCTTCCTGAGAGAGAATGCCTACTA
TGACAGCAGCGTGGTGGGCCGCTACTGTGAGAAGCGAGACCCCCATCTGGCCTGTGTTGCCTATGAGCGGGGGCAGTGTGACCTTGAGCT
CATCAAGGTGTGCAATGAGAATTCTCTGTTCAAAAGCGAGGCCCGCTACCTGGTATGCAGAAAGGATCCGGAGCTCTGGGCTCACGTCCT
TGAGGAGACCAACCCATCCAGGAGACAGCTAATTGACCAGGTGGTACAGACAGCATTGTCAGAAACACGGGATCCTGAAGAGATTTCGGT
CACTGTCAAAGCCTTTATGACAGCCGACCTGCCTAATGAACTGATTGAACTGCTGGAGAAGATAGTTCTGGATAACTCTGTCTTCAGCGA
GCACAGGAATCTACAGAATCTGTTGATCCTGACTGCCATCAAGGCAGACCGCACACGGGTCATGGAGTACATCAGCCGCCTGGACAACTA
TGACGCACTGGACATCGCGAGCATCGCTGTCAGCAGCGCACTGTATGAGGAGGCCTTCACCGTTTTCCACAAGTTTGATATGAATGCCTC
AGCAATCCAGGTCCTGATCGAGCACATTGGAAACCTGGACCGGGCATATGAGTTTGCGGAGAGATGCAATGAGCCTGCTGTGTGGAGTCA
GCTGGCCCAAGCCCAGCTCCAGAAAGATTTGGTGAAGGAAGCCATCAACTCCTATATCAGAGGGGACGACCCTTCCTCTTACCTGGAAGT
TGTTCAGTCAGCCAGCAGGAGCAACAACTGGGAGGATCTAGTTAAATTTCTGCAGATGGCCAGGAAAAAGGGCCGTGAGTCCTATATAGA
GACTGAACTTATTTTTGCCTTGGCTAAAACCAGCCGTGTTTCTGAGCTAGAAGATTTTATTAATGGACCCAACAATGCCCACATCCAGCA
GGTCGGGGACCGCTGTTACGAGGAGGGAATGTACGAGGCTGCCAAGCTGCTCTATAGCAATGTTTCTAACTTTGCCCGCCTGGCTTCCAC
CTTGGTTCACCTCGGTGAGTATCAGGCAGCAGTGGACAACAGCCGCAAGGCCAGCAGCACCCGGACGTGGAAGGAGGTGTGCTTTGCCTG
CATGGATGGACAAGAGTTCCGCTTCGCACAGCTGTGTGGTCTTCACATCGTCATTCATGCAGATGAGCTGGAGGAGCTGATGTGCTATTA
CCAGGATCGTGGCTACTTTGAGGAGCTGATCTTGCTGTTGGAAGCGGCCCTGGGCCTGGAGCGGGCCCACATGGGCATGTTCACTGAGCT
GGCCATCCTCTACTCCAAATTCAAGCCACAGAAGATGCTGGAGCATCTGGAGCTTTTCTGGTCCCGTGTCAACATCCCAAAGGTGCTGAG
GGCTGCAGAGCAGGCACACCTGTGGGCTGAGCTGGTGTTCCTCTATGACAAGTACGAGGAGTATGACAATGCTGTGCTCACCATGATGAG
CCACCCCACTGAGGCCTGGAAGGAGGGTCAGTTCAAGGACATCATTACCAAGGTTGCCAACGTCGAGCTCTGTTACAGAGCCCTGCAGTT
CTATTTGGATTACAAACCACTGCTCATCAATGACCTGCTGCTGGTGCTTTCACCCCGGCTGGACCACACCTGGACAGTCAGTTTCTTTTC
AAAGGCAGGTCAGCTGCCCCTGGTGAAGCCTTACCTGCGGTCAGTCCAGAGCCACAACAACAAGAGTGTGAATGAGGCACTCAACCACCT
GCTGACAGAGGAGGAGGACTATCAGGGCTTAAGGGCATCTATCGATGCCTATGACAACTTTGACAACATCAGCCTGGCTCAGCAGCTGGA
GAAGCATCAGCTGATGGAGTTCAGGTGCATTGCGGCCTATCTGTACAAGGGCAATAACTGGTGGGCCCAGAGCGTGGAGCTCTGCAAGAA
GGATCATCTCTACAAGGATGCCATGCAGCATGCTGCAGAGTCGCGGGATGCTGAGCTGGCCCAGAAGTTGCTGCAGTGGTTCCTGGAGGA
AGGCAAGAGGGAGTGCTTCGCAGCTTGTCTCTTCACCTGCTATGACCTGCTTCGCCCAGACATGGTGCTTGAGCTGGCCTGGAGGCACAA
CCTCGTGGACTTGGCCATGCCCTACTTCATCCAGGTGATGAGGGAGTACCTGAGCAAGGTGGACAAACTGGATGCCTTGGAGAGTCTGCG
CAAGCAAGAGGAGCATGTGACAGAGCCTGCCCCTCTCGTGTTTGATTTTGATGGGCATGAATGAGACCCAGCTGATTGCACTAAGCCCTG
CCGTGGGCCCAGCCCCTGCCAGCTTCCCCTATGGATATGCCTCTGCTCCCAACTTCGCCAGCCTCCAATGTACAACTTCCGCGTGTAGTG
GGCGTTGTCACCACCCACCCTACCTGCAGAGTTACTAACTTCTCCAAGGAGCATGTCACTCCAGCAGCACAGGGGACGCAATGGGAGGCA
GGGACACCTGGACAATATTTATTTTTGCTGAAACCCAATGACGGCAACCTCTGAGCCATCCCAGAGCCTGGGGAGGCCAGGGTAGAGGCT
GACGGCGCAAGACCAGCTTTAGCCGACAACAGAGACTGGACTGTGGGCCCTCCTGCTGGAGCCAGGCCTTCCTCCTGGGCGCCTCCGACT
GGCTGGAGCTGCCCCCTCCAGGCCAGTTTGAAGACTACATGAACACGTCTTGTTTGGAGGTACCGGACCTCATAAAAGGACTCTCAGCCT

>22400_22400_6_DGCR2-CLTCL1_DGCR2_chr22_19076881_ENST00000545799_CLTCL1_chr22_19263353_ENST00000427926_length(amino acids)=1675AA_BP=3
MSPSRCGQSCGATLGSLRVAAAPSSASPSPGSVTAGRLARMRATKPTVQLQNLGINPANIGFSTLTMESDKFICIREKVGEQAQVTIIDM
SDPMAPIRRPISAESAIMNPASKVIALKAGKTLQIFNIEMKSKMKAHTMAEEVIFWKWVSVNTVALVTETAVYHWSMEGDSQPMKMFDRH
TSLVGCQVIHYRTDEYQKWLLLVGISAQQNRVVGAMQLYSVDRKVSQPIEGHAAAFAEFKMEGNAKPATLFCFAVRNPTGGKLHIIEVGQ
PAAGNQPFVKKAVDVFFPPEAQNDFPVAMQIGAKHGVIYLITKYGYLHLYDLESGVCICMNRISADTIFVTAPHKPTSGIIGVNKKGQVL
SVCVEEDNIVNYATNVLQNPDLGLRLAVRSNLAGAEKLFVRKFNTLFAQGSYAEAAKVAASAPKGILRTRETVQKFQSIPAQSGQASPLL
QYFGILLDQGQLNKLESLELCHLVLQQGRKQLLEKWLKEDKLECSEELGDLVKTTDPMLALSVYLRANVPSKVIQCFAETGQFQKIVLYA
KKVGYTPDWIFLLRGVMKISPEQGLQFSRMLVQDEEPLANISQIVDIFMENSLIQQCTSFLLDALKNNRPAEGLLQTWLLEMNLVHAPQV
ADAILGNKMFTHYDRAHIAQLCEKAGLLQQALEHYTDLYDIKRAVVHTHLLNPEWLVNFFGSLSVEDSVECLHAMLSANIRQNLQLCVQV
ASKYHEQLGTQALVELFESFKSYKGLFYFLGSIVNFSQDPDVHLKYIQAACKTGQIKEVERICRESSCYNPERVKNFLKEAKLTDQLPLI
IVCDRFGFVHDLVLYLYRNNLQRYIEIYVQKVNPSRTPAVIGGLLDVDCSEEVIKHLIMAVRGQFSTDELVAEVEKRNRLKLLLPWLESQ
IQEGCEEPATHNALAKIYIDSNNSPECFLRENAYYDSSVVGRYCEKRDPHLACVAYERGQCDLELIKVCNENSLFKSEARYLVCRKDPEL
WAHVLEETNPSRRQLIDQVVQTALSETRDPEEISVTVKAFMTADLPNELIELLEKIVLDNSVFSEHRNLQNLLILTAIKADRTRVMEYIS
RLDNYDALDIASIAVSSALYEEAFTVFHKFDMNASAIQVLIEHIGNLDRAYEFAERCNEPAVWSQLAQAQLQKDLVKEAINSYIRGDDPS
SYLEVVQSASRSNNWEDLVKFLQMARKKGRESYIETELIFALAKTSRVSELEDFINGPNNAHIQQVGDRCYEEGMYEAAKLLYSNVSNFA
RLASTLVHLGEYQAAVDNSRKASSTRTWKEVCFACMDGQEFRFAQLCGLHIVIHADELEELMCYYQDRGYFEELILLLEAALGLERAHMG
MFTELAILYSKFKPQKMLEHLELFWSRVNIPKVLRAAEQAHLWAELVFLYDKYEEYDNAVLTMMSHPTEAWKEGQFKDIITKVANVELCY
RALQFYLDYKPLLINDLLLVLSPRLDHTWTVSFFSKAGQLPLVKPYLRSVQSHNNKSVNEALNHLLTEEEDYQGLRASIDAYDNFDNISL
AQQLEKHQLMEFRCIAAYLYKGNNWWAQSVELCKKDHLYKDAMQHAAESRDAELAQKLLQWFLEEGKRECFAACLFTCYDLLRPDMVLEL

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Fusion Gene PPI Analysis for DGCR2-CLTCL1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for DGCR2-CLTCL1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for DGCR2-CLTCL1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneDGCR2C0036341Schizophrenia1CTD_human
TgeneC0002768Congenital Pain Insensitivity1GENOMICS_ENGLAND