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Center for Computational Systems Medicine
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Fusion Gene and Fusion Protein Summary

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Fusion Amino Acid Sequences (multiple BPs and multiple gene isoforms)

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Fusion Protein Breakpoint Sequences - (for the Screening of the FusionNeoAntigens)

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Potential FusionNeoAntigens in HLA I - (netMHCpan v4.1 + deepHLApan v1.1)

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Potential FusionNeoAntigens in HLA II - (netMHCIIpan v4.1)

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Fusion Breakpoint 14 AA Peptide Structure - (RoseTTAFold)

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Filtering FusionNeoAntigens Through Checking the Interaction with HLAs in 3D - (Glide)

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Vaccine Design for the FusionNeoAntigens (RNA/protein sequences)

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Potential target of CAR-T therapy development

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Information on the samples that have these potential fusion neoantigens

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Fusion Protein Targeting Drugs - (Manual Curation)

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Fusion Protein Related diseases - (Manual Curation)

Fusion Protein:CACNA1D-GNL3

Fusion Gene and Fusion Protein Summary

check button Fusion gene summary
Fusion partner gene informationFusion gene name: CACNA1D-GNL3
FusionPDB ID: 12320
FusionGDB2.0 ID: 12320
HgeneTgene
Gene symbol

CACNA1D

GNL3

Gene ID

776

26354

Gene namecalcium voltage-gated channel subunit alpha1 DG protein nucleolar 3
SynonymsCACH3|CACN4|CACNL1A2|CCHL1A2|Cav1.3|PASNA|SANDDC77032|E2IG3|NNP47|NS
Cytomap

3p21.1

3p21.1

Type of geneprotein-codingprotein-coding
Descriptionvoltage-dependent L-type calcium channel subunit alpha-1Dcalcium channel, L type, alpha-1 polypeptidecalcium channel, neuroendocrine/brain-type, alpha 1 subunitcalcium channel, voltage-dependent, L type, alpha 1D subunitvoltage-gated calcium channel aguanine nucleotide-binding protein-like 3E2-induced gene 3 proteinestradiol-induced nucleotide binding proteinguanine nucleotide binding protein-like 3 (nucleolar)novel nucleolar protein 47nucleolar GTP-binding protein 3nucleostemin
Modification date2020031320200327
UniProtAcc

Q01668

Main function of 5'-partner protein: FUNCTION: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1D gives rise to L-type calcium currents. Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group. They are blocked by dihydropyridines (DHP), phenylalkylamines, and by benzothiazepines. {ECO:0000269|PubMed:18482979, ECO:0000269|PubMed:25620733, ECO:0000269|PubMed:28472301}.

Q9NVN8

Main function of 5'-partner protein: FUNCTION: Stabilizes TERF1 telomeric association by preventing TERF1 recruitment by PML. Stabilizes TERF1 protein by preventing its ubiquitination and hence proteasomal degradation. Does so by interfering with TERF1-binding to FBXO4 E3 ubiquitin-protein ligase. Required for cell proliferation. By stabilizing TRF1 protein during mitosis, promotes metaphase-to-anaphase transition. Stabilizes MDM2 protein by preventing its ubiquitination, and hence proteasomal degradation. By acting on MDM2, may affect TP53 activity. Required for normal processing of ribosomal pre-rRNA. Binds GTP. {ECO:0000269|PubMed:16251348, ECO:0000269|PubMed:17034816, ECO:0000269|PubMed:19487455, ECO:0000269|PubMed:21132010}.
Ensembl transtripts involved in fusion geneENST idsENST00000288139, ENST00000350061, 
ENST00000422281, ENST00000540742, 
ENST00000498251, ENST00000544977, 
ENST00000460073, ENST00000394799, 
ENST00000418458, 
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)* DoF score11 X 9 X 5=4954 X 8 X 4=128
# samples 156
** MAII scorelog2(15/495*10)=-1.72246602447109
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(6/128*10)=-1.09310940439148
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Fusion gene context

PubMed: CACNA1D [Title/Abstract] AND GNL3 [Title/Abstract] AND fusion [Title/Abstract]

Fusion neoantigen context

PubMed: CACNA1D [Title/Abstract] AND GNL3 [Title/Abstract] AND neoantigen [Title/Abstract]

Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)CACNA1D(53804579)-GNL3(52724608), # samples:3
Anticipated loss of major functional domain due to fusion event.CACNA1D-GNL3 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
CACNA1D-GNL3 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
CACNA1D-GNL3 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
CACNA1D-GNL3 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
CACNA1D-GNL3 seems lost the major protein functional domain in Hgene partner, which is a CGC due to the frame-shifted ORF.
CACNA1D-GNL3 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
CACNA1D-GNL3 seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
CACNA1D-GNL3 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneCACNA1D

GO:0006816

calcium ion transport

11160515

HgeneCACNA1D

GO:0051928

positive regulation of calcium ion transport

1309651

HgeneCACNA1D

GO:0070509

calcium ion import

1309651

TgeneGNL3

GO:0017145

stem cell division

25522312



check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr3:53804579/chr3:52724608)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonRetention analysis results of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features, are available here.

check buttonFusion gene breakpoints across CACNA1D (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across GNL3 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure


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Fusion Amino Acid Sequences


check buttonFusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)
BP loci
(transcript)
Predicted start
(transcript)
Predicted stop
(transcript)
Seq length
(amino acids)
ENST00000350061CACNA1Dchr353804579+ENST00000418458GNL3chr352724960+5768455551155501679
ENST00000350061CACNA1Dchr353804579+ENST00000394799GNL3chr352724960+5768455551155501679
ENST00000288139CACNA1Dchr353804579+ENST00000418458GNL3chr352724960+5435422211852171699
ENST00000288139CACNA1Dchr353804579+ENST00000394799GNL3chr352724960+5435422211852171699
ENST00000422281CACNA1Dchr353804579+ENST00000418458GNL3chr352724960+52123999049941664
ENST00000422281CACNA1Dchr353804579+ENST00000394799GNL3chr352724960+52123999049941664
ENST00000540742CACNA1Dchr353804579+ENST00000418458GNL3chr352724960+1965752171747576
ENST00000540742CACNA1Dchr353804579+ENST00000394799GNL3chr352724960+1965752171747576
ENST00000350061CACNA1Dchr353804579+ENST00000418458GNL3chr352724961+5768455551155501679
ENST00000350061CACNA1Dchr353804579+ENST00000394799GNL3chr352724961+5768455551155501679
ENST00000288139CACNA1Dchr353804579+ENST00000418458GNL3chr352724961+5435422211852171699
ENST00000288139CACNA1Dchr353804579+ENST00000394799GNL3chr352724961+5435422211852171699
ENST00000422281CACNA1Dchr353804579+ENST00000418458GNL3chr352724961+52123999049941664
ENST00000422281CACNA1Dchr353804579+ENST00000394799GNL3chr352724961+52123999049941664
ENST00000540742CACNA1Dchr353804579+ENST00000418458GNL3chr352724961+1965752171747576
ENST00000540742CACNA1Dchr353804579+ENST00000394799GNL3chr352724961+1965752171747576

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000350061ENST00000418458CACNA1Dchr353804579+GNL3chr352724960+0.0006694640.9993305
ENST00000350061ENST00000394799CACNA1Dchr353804579+GNL3chr352724960+0.0006694640.9993305
ENST00000288139ENST00000418458CACNA1Dchr353804579+GNL3chr352724960+0.000451980.999548
ENST00000288139ENST00000394799CACNA1Dchr353804579+GNL3chr352724960+0.000451980.999548
ENST00000422281ENST00000418458CACNA1Dchr353804579+GNL3chr352724960+0.0008201320.9991799
ENST00000422281ENST00000394799CACNA1Dchr353804579+GNL3chr352724960+0.0008201320.9991799
ENST00000540742ENST00000418458CACNA1Dchr353804579+GNL3chr352724960+0.0008762750.99912375
ENST00000540742ENST00000394799CACNA1Dchr353804579+GNL3chr352724960+0.0008762750.99912375
ENST00000350061ENST00000418458CACNA1Dchr353804579+GNL3chr352724961+0.0006694640.9993305
ENST00000350061ENST00000394799CACNA1Dchr353804579+GNL3chr352724961+0.0006694640.9993305
ENST00000288139ENST00000418458CACNA1Dchr353804579+GNL3chr352724961+0.000451980.999548
ENST00000288139ENST00000394799CACNA1Dchr353804579+GNL3chr352724961+0.000451980.999548
ENST00000422281ENST00000418458CACNA1Dchr353804579+GNL3chr352724961+0.0008201320.9991799
ENST00000422281ENST00000394799CACNA1Dchr353804579+GNL3chr352724961+0.0008201320.9991799
ENST00000540742ENST00000418458CACNA1Dchr353804579+GNL3chr352724961+0.0008762750.99912375
ENST00000540742ENST00000394799CACNA1Dchr353804579+GNL3chr352724961+0.0008762750.99912375

check button Predicted full-length fusion amino acid sequences. For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among all the predicted ones.

Get the fusion protein sequences from here.

Fusion protein sequence information is available in the fasta format.
>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

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Fusion Protein Breakpoint Sequences for CACNA1D-GNL3

check button +/-13 AA sequence from the breakpoints of the fusion protein sequences.
HgeneHchrHbpTgeneTchrTbpLength(fusion protein)BP in fusion proteinPeptide
CACNA1Dchr353804579GNL3chr35272496039991331EGIRTLLWTFIKSFQRVKAKKNAAPF
CACNA1Dchr353804579GNL3chr35272496042221366EGIRTLLWTFIKSFQRVKAKKNAAPF
CACNA1Dchr353804579GNL3chr35272496045551346EGIRTLLWTFIKSFQRVKAKKNAAPF
CACNA1Dchr353804579GNL3chr352724960752243EGIRTLLWTFIKSFQRVKAKKNAAPF
CACNA1Dchr353804579GNL3chr35272496139991331EGIRTLLWTFIKSFQRVKAKKNAAPF
CACNA1Dchr353804579GNL3chr35272496142221366EGIRTLLWTFIKSFQRVKAKKNAAPF
CACNA1Dchr353804579GNL3chr35272496145551346EGIRTLLWTFIKSFQRVKAKKNAAPF
CACNA1Dchr353804579GNL3chr352724961752243EGIRTLLWTFIKSFQRVKAKKNAAPF

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Potential FusionNeoAntigen Information of CACNA1D-GNL3 in HLA I

check button Multiple sequence alignments of the potential FusionNeoAntigens per fusion breakpoints. If the MSA is empty, then it means that there were predicted fusion neoantigens in this fusion breakpoint, but those predicted fusion neoantigens were not across the breakpoint, which is not fusion-specific.
CACNA1D-GNL3_53804579_52724960.msa

check button Potential FusionNeoAntigen Information
* We used NetMHCpan v4.1 (%rank<0.5) and deepHLApan v1.1 (immunogenic score>0.5)
Fusion geneHchrHbpTgeneTchrTbpHLA IFusionNeoAntigen peptideBinding scoreImmunogenic scoreNeoantigen start (at BP 13)Neoantigen end (at BP 13)
CACNA1D-GNL3chr353804579chr3527249604222HLA-A30:08KSFQRVKAK0.99860.52851120
CACNA1D-GNL3chr353804579chr3527249604222HLA-A32:13LLWTFIKSF0.92280.845514
CACNA1D-GNL3chr353804579chr3527249604222HLA-A30:08KSFQRVKAKK0.99760.57621121
CACNA1D-GNL3chr353804579chr3527249604222HLA-B57:01RTLLWTFIKSF0.99880.8621314
CACNA1D-GNL3chr353804579chr3527249604222HLA-B57:03RTLLWTFIKSF0.99260.8625314
CACNA1D-GNL3chr353804579chr3527249604222HLA-A30:01KSFQRVKAK0.99880.72121120
CACNA1D-GNL3chr353804579chr3527249604222HLA-A32:01LLWTFIKSF0.9640.8989514
CACNA1D-GNL3chr353804579chr3527249604222HLA-A30:01FIKSFQRVK0.92780.6883918
CACNA1D-GNL3chr353804579chr3527249604222HLA-A30:01SFQRVKAKK0.90750.86351221
CACNA1D-GNL3chr353804579chr3527249604222HLA-C04:04TFIKSFQRV0.36550.6277817
CACNA1D-GNL3chr353804579chr3527249604222HLA-C06:06TFIKSFQRV0.11340.9588817
CACNA1D-GNL3chr353804579chr3527249604222HLA-A30:01KSFQRVKAKK0.99760.77491121
CACNA1D-GNL3chr353804579chr3527249604222HLA-B57:10RTLLWTFIKSF0.99880.8621314
CACNA1D-GNL3chr353804579chr3527249604222HLA-A32:01RTLLWTFIKSF0.99040.8212314

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Potential FusionNeoAntigen Information of CACNA1D-GNL3 in HLA II

check button Multiple sequence alignments of the potential FusionNeoAntigens per fusion breakpoints. If the MSA is empty, then it means that there were predicted fusion neoantigens in this fusion breakpoint, but those predicted fusion neoantigens were not across the breakpoint, which is not fusion-specific.
CACNA1D-GNL3_53804579_52724960.msa

check button Potential FusionNeoAntigen Information
* We used NetMHCIIpan v4.1 (%rank<0.5).
Fusion geneHchrHbpTgeneTchrTbpHLA IIFusionNeoAntigen peptideNeoantigen start (at BP 13)Neoantigen end (at BP 13)
CACNA1D-GNL3chr353804579chr3527249604222DRB1-0103IKSFQRVKAKKNAAP1025
CACNA1D-GNL3chr353804579chr3527249604222DRB1-0103FIKSFQRVKAKKNAA924
CACNA1D-GNL3chr353804579chr3527249604222DRB1-0804WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-0804LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-0804TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-0806WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-0810WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-0812WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-0812LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-0815WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-0820WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-0820LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-0820TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-0822WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-0828WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-0828LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-0828TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-0830WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-0831WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-0831LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-0831TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1102WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1102LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1102TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1102LLWTFIKSFQRVKAK520
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1103WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1103LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1103TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1104WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1104LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1104TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1106WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1106LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1106TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1111WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1111LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1111TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1113WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1113LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1113TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1114WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1114LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1114TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1116WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1116LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1116TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1116LLWTFIKSFQRVKAK520
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1117WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1118WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1118LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1118TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1119WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1120WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1120LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1120TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1121WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1121TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1121LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1125WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1125LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1125TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1130IKSFQRVKAKKNAAP1025
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1130FIKSFQRVKAKKNAA924
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1131WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1132WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1134WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1134LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1134TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1135WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1135LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1135TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1136WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1136LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1136TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1138WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1138LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1138TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1141WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1141LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1141TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1142WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1142LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1142TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1143WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1143LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1143TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1144WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1144LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1144TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1145WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1145TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1145LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1146WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1146LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1146TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1147WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1147LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1147TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1148WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1148LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1148TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1148LLWTFIKSFQRVKAK520
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1150WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1150LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1152WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1154WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1154LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1154TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1155WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1155TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1155LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1156WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1156LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1157WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1157LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1157TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1158WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1158LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1158TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1159WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1159TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1159LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1160WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1160LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1160TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1163WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1163LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1163TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1164WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1165WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1165LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1165TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1165LLWTFIKSFQRVKAK520
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1167WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1167LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1167TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1168WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1168LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1169WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1169LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1169TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1170WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1170TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1170LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1172WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1176WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1176LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1176TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1177WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1177LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1177TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1178WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1178LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1178TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1182WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1182LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1182TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1183WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1184WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1184LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1184TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1185WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1185LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1185TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1186WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1186TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1188WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1188LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1189WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1189LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1189TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1192WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1192LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1192TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1204WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1204LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1204TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1209WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1209LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1209TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1301WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1301LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1301TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1301LLWTFIKSFQRVKAK520
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1302WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1302LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1302TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1304WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1304LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1304TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1306WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1306LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1306TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1308WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1308LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1308TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1308LLWTFIKSFQRVKAK520
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1309WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1309LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1309TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1309LLWTFIKSFQRVKAK520
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1311WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1311LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1311TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1315WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1315LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1315TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1315LLWTFIKSFQRVKAK520
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1316WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1316TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1317WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1317LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1317TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1317LLWTFIKSFQRVKAK520
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1318WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1318LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1318TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1319WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1319TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1319LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1319LLWTFIKSFQRVKAK520
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1320WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1320LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1320TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1322WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1322LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1322TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1322LLWTFIKSFQRVKAK520
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1323WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1323LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1323TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1324WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1324LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1324TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1326WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1327WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1327TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1327LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1329WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1329LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1332WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1332LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1332TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1334WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1334LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1334TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1335WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1335LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1335TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1335LLWTFIKSFQRVKAK520
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1336WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1336LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1336TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1339WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1339LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1339TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1341WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1342WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1342LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1342TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1343WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1343LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1343TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1344WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1344LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1344TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1348WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1348LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1348TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1351WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1351LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1351TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1351LLWTFIKSFQRVKAK520
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1352WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1352LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1352TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1352LLWTFIKSFQRVKAK520
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1353WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1353TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1353LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1353LLWTFIKSFQRVKAK520
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1354WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1354LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1354TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1357WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1357LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1357TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1357LLWTFIKSFQRVKAK520
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1358WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1359WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1359LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1359TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1359LLWTFIKSFQRVKAK520
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1361WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1361LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1361TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1363WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1363LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1363TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1364WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1364LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1364TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1364LLWTFIKSFQRVKAK520
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1367IKSFQRVKAKKNAAP1025
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1368WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1368LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1368TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1368LLWTFIKSFQRVKAK520
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1369WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1369LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1369TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1369LLWTFIKSFQRVKAK520
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1370WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1370LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1370TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1370LLWTFIKSFQRVKAK520
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1371WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1371LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1371TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1372WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1372LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1372TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1372LLWTFIKSFQRVKAK520
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1373WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1373LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1373TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1374WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1374LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1374TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1375WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1375LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1375TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1376WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1376LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1376TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1377WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1378WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1378LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1378TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1379WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1379LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1379TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1379LLWTFIKSFQRVKAK520
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1380WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1380LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1380TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1380LLWTFIKSFQRVKAK520
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1382WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1383WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1383LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1383TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1383LLWTFIKSFQRVKAK520
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1384WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1384LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1384TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1384LLWTFIKSFQRVKAK520
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1386WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1387WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1387LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1387TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1387LLWTFIKSFQRVKAK520
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1391WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1391LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1391TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1391LLWTFIKSFQRVKAK520
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1392WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1392LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1392TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1392LLWTFIKSFQRVKAK520
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1393WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1393LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1393TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1397WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1397LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1397TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1398WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1398LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1398TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1399WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1399LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1399TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1403WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1405WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1406WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1406LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1406TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1408WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1411WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1411LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1412WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1412LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1412TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1415WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1415LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1415TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1416WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1416LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1416TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1417WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1417LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1417TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1418WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1418LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1420WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1420LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1420TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1421WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1423WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1424WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1424LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1424TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1427WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1429WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1429LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1429TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1431WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1433WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1434WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1434LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1434TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1437WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1437LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1437TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1437LLWTFIKSFQRVKAK520
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1440WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1443WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1445WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1445LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1452WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1452LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1455WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1456WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1459WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1464WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1464LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1465WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1465LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1465TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1467WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1467TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1467LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1472WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1472LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1473WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1474WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1477WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1478WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1478LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1478TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1480WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1480LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1481WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1481LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1481TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1483WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1483LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1483TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1484WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1484LWTFIKSFQRVKAKK621
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1484TFIKSFQRVKAKKNA823
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1491WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB1-1496WTFIKSFQRVKAKKN722
CACNA1D-GNL3chr353804579chr3527249604222DRB5-0101TLLWTFIKSFQRVKA419
CACNA1D-GNL3chr353804579chr3527249604222DRB5-0101RTLLWTFIKSFQRVK318
CACNA1D-GNL3chr353804579chr3527249604222DRB5-0102TLLWTFIKSFQRVKA419
CACNA1D-GNL3chr353804579chr3527249604222DRB5-0102IKSFQRVKAKKNAAP1025
CACNA1D-GNL3chr353804579chr3527249604222DRB5-0102RTLLWTFIKSFQRVK318
CACNA1D-GNL3chr353804579chr3527249604222DRB5-0102FIKSFQRVKAKKNAA924
CACNA1D-GNL3chr353804579chr3527249604222DRB5-0103IKSFQRVKAKKNAAP1025
CACNA1D-GNL3chr353804579chr3527249604222DRB5-0103FIKSFQRVKAKKNAA924
CACNA1D-GNL3chr353804579chr3527249604222DRB5-0103TLLWTFIKSFQRVKA419
CACNA1D-GNL3chr353804579chr3527249604222DRB5-0103KSFQRVKAKKNAAPF1126
CACNA1D-GNL3chr353804579chr3527249604222DRB5-0103RTLLWTFIKSFQRVK318
CACNA1D-GNL3chr353804579chr3527249604222DRB5-0104IKSFQRVKAKKNAAP1025
CACNA1D-GNL3chr353804579chr3527249604222DRB5-0104TLLWTFIKSFQRVKA419
CACNA1D-GNL3chr353804579chr3527249604222DRB5-0104FIKSFQRVKAKKNAA924
CACNA1D-GNL3chr353804579chr3527249604222DRB5-0104RTLLWTFIKSFQRVK318
CACNA1D-GNL3chr353804579chr3527249604222DRB5-0105TLLWTFIKSFQRVKA419
CACNA1D-GNL3chr353804579chr3527249604222DRB5-0105RTLLWTFIKSFQRVK318
CACNA1D-GNL3chr353804579chr3527249604222DRB5-0108NTLLWTFIKSFQRVKA419
CACNA1D-GNL3chr353804579chr3527249604222DRB5-0108NIKSFQRVKAKKNAAP1025
CACNA1D-GNL3chr353804579chr3527249604222DRB5-0108NRTLLWTFIKSFQRVK318
CACNA1D-GNL3chr353804579chr3527249604222DRB5-0108NFIKSFQRVKAKKNAA924
CACNA1D-GNL3chr353804579chr3527249604222DRB5-0111TLLWTFIKSFQRVKA419
CACNA1D-GNL3chr353804579chr3527249604222DRB5-0111RTLLWTFIKSFQRVK318
CACNA1D-GNL3chr353804579chr3527249604222DRB5-0112IKSFQRVKAKKNAAP1025
CACNA1D-GNL3chr353804579chr3527249604222DRB5-0113TLLWTFIKSFQRVKA419
CACNA1D-GNL3chr353804579chr3527249604222DRB5-0113RTLLWTFIKSFQRVK318
CACNA1D-GNL3chr353804579chr3527249604222DRB5-0114TLLWTFIKSFQRVKA419
CACNA1D-GNL3chr353804579chr3527249604222DRB5-0114RTLLWTFIKSFQRVK318
CACNA1D-GNL3chr353804579chr3527249604222DRB5-0203TLLWTFIKSFQRVKA419
CACNA1D-GNL3chr353804579chr3527249604222DRB5-0203RTLLWTFIKSFQRVK318

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Fusion breakpoint peptide structures of CACNA1D-GNL3

check button3D structures of the fusion breakpoint peptide of 14AA sequence that have potential fusion neoantigens
* The minimum length of the amino acid sequence in RoseTTAFold is 14AA. Here, we predicted the 14AA fusion protein breakpoint sequence not the fusion neoantigen peptide, which is shorter than 14 AA.
File nameBPseqHgeneTgeneHchrHbpTchrTbpAAlen
5819LWTFIKSFQRVKAKCACNA1DGNL3chr353804579chr3527249604222

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Filtering FusionNeoAntigens Through Checking the Interaction with HLAs in 3D of CACNA1D-GNL3

check buttonVirtual screening between 25 HLAs (from PDB) and FusionNeoAntigens
* We used Glide to predict the interaction between HLAs and neoantigens.
HLA allelePDB IDFile nameBPseqDocking scoreGlide score
HLA-B14:023BVN5819LWTFIKSFQRVKAK-7.9962-8.1096
HLA-B14:023BVN5819LWTFIKSFQRVKAK-5.70842-6.74372
HLA-B52:013W395819LWTFIKSFQRVKAK-6.83737-6.95077
HLA-B52:013W395819LWTFIKSFQRVKAK-4.4836-5.5189
HLA-A11:014UQ25819LWTFIKSFQRVKAK-10.0067-10.1201
HLA-A11:014UQ25819LWTFIKSFQRVKAK-9.03915-10.0745
HLA-A24:025HGA5819LWTFIKSFQRVKAK-6.56204-6.67544
HLA-A24:025HGA5819LWTFIKSFQRVKAK-5.42271-6.45801
HLA-B44:053DX85819LWTFIKSFQRVKAK-7.85648-8.89178
HLA-B44:053DX85819LWTFIKSFQRVKAK-5.3978-5.5112
HLA-A02:016TDR5819LWTFIKSFQRVKAK-3.37154-4.40684

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Vaccine Design for the FusionNeoAntigens of CACNA1D-GNL3

check button mRNA and peptide sequences of FusionNeoAntigens that have potential interaction with HLA-Is.
Fusion geneHchrHbpTchrTbpStart in +/-13AAEnd in +/-13AAFusionNeoAntigen peptide sequenceFusionNeoAntigen RNA sequence
CACNA1D-GNL3chr353804579chr3527249601120KSFQRVKAKTTTCAGCGTGTGAAGGCAAAGAAGAAT
CACNA1D-GNL3chr353804579chr3527249601121KSFQRVKAKKTTTCAGCGTGTGAAGGCAAAGAAGAATGCT
CACNA1D-GNL3chr353804579chr3527249601221SFQRVKAKKCAGCGTGTGAAGGCAAAGAAGAATGCT
CACNA1D-GNL3chr353804579chr352724960314RTLLWTFIKSFTTGCTGTGGACTTTTATTAAGTCCTTTCAGCGT
CACNA1D-GNL3chr353804579chr352724960514LLWTFIKSFTGGACTTTTATTAAGTCCTTTCAGCGT
CACNA1D-GNL3chr353804579chr352724960817TFIKSFQRVATTAAGTCCTTTCAGCGTGTGAAGGCA
CACNA1D-GNL3chr353804579chr352724960918FIKSFQRVKAAGTCCTTTCAGCGTGTGAAGGCAAAG

check button mRNA and peptide sequences of FusionNeoAntigens that have potential interaction with HLA-IIs.
Fusion geneHchrHbpTchrTbpStart in +/-13AAEnd in +/-13AAFusionNeoAntigen peptideFusionNEoAntigen RNA sequence
CACNA1D-GNL3chr353804579chr3527249601025IKSFQRVKAKKNAAPTCCTTTCAGCGTGTGAAGGCAAAGAAGAATGCTGCTCCATTCAGA
CACNA1D-GNL3chr353804579chr3527249601126KSFQRVKAKKNAAPFTTTCAGCGTGTGAAGGCAAAGAAGAATGCTGCTCCATTCAGAAGT
CACNA1D-GNL3chr353804579chr352724960318RTLLWTFIKSFQRVKTTGCTGTGGACTTTTATTAAGTCCTTTCAGCGTGTGAAGGCAAAG
CACNA1D-GNL3chr353804579chr352724960419TLLWTFIKSFQRVKACTGTGGACTTTTATTAAGTCCTTTCAGCGTGTGAAGGCAAAGAAG
CACNA1D-GNL3chr353804579chr352724960520LLWTFIKSFQRVKAKTGGACTTTTATTAAGTCCTTTCAGCGTGTGAAGGCAAAGAAGAAT
CACNA1D-GNL3chr353804579chr352724960621LWTFIKSFQRVKAKKACTTTTATTAAGTCCTTTCAGCGTGTGAAGGCAAAGAAGAATGCT
CACNA1D-GNL3chr353804579chr352724960722WTFIKSFQRVKAKKNTTTATTAAGTCCTTTCAGCGTGTGAAGGCAAAGAAGAATGCTGCT
CACNA1D-GNL3chr353804579chr352724960823TFIKSFQRVKAKKNAATTAAGTCCTTTCAGCGTGTGAAGGCAAAGAAGAATGCTGCTCCA
CACNA1D-GNL3chr353804579chr352724960924FIKSFQRVKAKKNAAAAGTCCTTTCAGCGTGTGAAGGCAAAGAAGAATGCTGCTCCATTC

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Information of the samples that have these potential fusion neoantigens of CACNA1D-GNL3

check button These samples were reported as having these fusion breakpoints. For individual breakpoints, we checked the open reading frames considering multiple gene isoforms and chose the in-frame fusion genes only. Then, we made fusion protein sequences and predicted the fusion neoantigens. These fusion-positive samples may have these potential fusion neoantigens.
Cancer typeFusion geneHchrHbpHenstTchrTbpTenstSample
ESCACACNA1D-GNL3chr353804579ENST00000288139chr352724960ENST00000394799TCGA-L5-A4OS

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Potential target of CAR-T therapy development for CACNA1D-GNL3

check button Predicted 3D structure. We used RoseTTAFold.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, to provide the retention of the transmembrane domain, we only show the protein feature retention information of those transmembrane features


* Minus value of BPloci means that the break point is located before the CDS.
- In-frame and retained 'Transmembrane'.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCACNA1Dchr3:53804579chr3:52724960ENST00000288139+33491018_103713682182.0TransmembraneHelical%3B Name%3DS5 of repeat III
HgeneCACNA1Dchr3:53804579chr3:52724960ENST00000288139+33491128_114813682182.0TransmembraneHelical%3B Name%3DS6 of repeat III
HgeneCACNA1Dchr3:53804579chr3:52724960ENST00000288139+33491206_122413682182.0TransmembraneHelical%3B Name%3DS1 of repeat IV
HgeneCACNA1Dchr3:53804579chr3:52724960ENST00000288139+33491240_125913682182.0TransmembraneHelical%3B Name%3DS2 of repeat IV
HgeneCACNA1Dchr3:53804579chr3:52724960ENST00000288139+33491267_128813682182.0TransmembraneHelical%3B Name%3DS3 of repeat IV
HgeneCACNA1Dchr3:53804579chr3:52724960ENST00000288139+3349127_14513682182.0TransmembraneHelical%3B Name%3DS1 of repeat I
HgeneCACNA1Dchr3:53804579chr3:52724960ENST00000288139+33491314_133313682182.0TransmembraneHelical%3B Name%3DS4 of repeat IV
HgeneCACNA1Dchr3:53804579chr3:52724960ENST00000288139+3349164_18313682182.0TransmembraneHelical%3B Name%3DS2 of repeat I
HgeneCACNA1Dchr3:53804579chr3:52724960ENST00000288139+3349196_21413682182.0TransmembraneHelical%3B Name%3DS3 of repeat I
HgeneCACNA1Dchr3:53804579chr3:52724960ENST00000288139+3349236_25413682182.0TransmembraneHelical%3B Name%3DS4 of repeat I
HgeneCACNA1Dchr3:53804579chr3:52724960ENST00000288139+3349274_29313682182.0TransmembraneHelical%3B Name%3DS5 of repeat I
HgeneCACNA1Dchr3:53804579chr3:52724960ENST00000288139+3349382_40613682182.0TransmembraneHelical%3B Name%3DS6 of repeat I
HgeneCACNA1Dchr3:53804579chr3:52724960ENST00000288139+3349524_54313682182.0TransmembraneHelical%3B Name%3DS1 of repeat II
HgeneCACNA1Dchr3:53804579chr3:52724960ENST00000288139+3349559_57713682182.0TransmembraneHelical%3B Name%3DS2 of repeat II
HgeneCACNA1Dchr3:53804579chr3:52724960ENST00000288139+3349586_60413682182.0TransmembraneHelical%3B Name%3DS3 of repeat II
HgeneCACNA1Dchr3:53804579chr3:52724960ENST00000288139+3349615_63313682182.0TransmembraneHelical%3B Name%3DS4 of repeat II
HgeneCACNA1Dchr3:53804579chr3:52724960ENST00000288139+3349653_67313682182.0TransmembraneHelical%3B Name%3DS5 of repeat II
HgeneCACNA1Dchr3:53804579chr3:52724960ENST00000288139+3349728_75213682182.0TransmembraneHelical%3B Name%3DS6 of repeat II
HgeneCACNA1Dchr3:53804579chr3:52724960ENST00000288139+3349887_90513682182.0TransmembraneHelical%3B Name%3DS1 of repeat III
HgeneCACNA1Dchr3:53804579chr3:52724960ENST00000288139+3349922_94113682182.0TransmembraneHelical%3B Name%3DS2 of repeat III
HgeneCACNA1Dchr3:53804579chr3:52724960ENST00000288139+3349954_97213682182.0TransmembraneHelical%3B Name%3DS3 of repeat III
HgeneCACNA1Dchr3:53804579chr3:52724960ENST00000288139+3349979_99813682182.0TransmembraneHelical%3B Name%3DS4 of repeat III
HgeneCACNA1Dchr3:53804579chr3:52724960ENST00000350061+32481018_103713482162.0TransmembraneHelical%3B Name%3DS5 of repeat III
HgeneCACNA1Dchr3:53804579chr3:52724960ENST00000350061+32481128_114813482162.0TransmembraneHelical%3B Name%3DS6 of repeat III
HgeneCACNA1Dchr3:53804579chr3:52724960ENST00000350061+32481206_122413482162.0TransmembraneHelical%3B Name%3DS1 of repeat IV
HgeneCACNA1Dchr3:53804579chr3:52724960ENST00000350061+32481240_125913482162.0TransmembraneHelical%3B Name%3DS2 of repeat IV
HgeneCACNA1Dchr3:53804579chr3:52724960ENST00000350061+32481267_128813482162.0TransmembraneHelical%3B Name%3DS3 of repeat IV
HgeneCACNA1Dchr3:53804579chr3:52724960ENST00000350061+3248127_14513482162.0TransmembraneHelical%3B Name%3DS1 of repeat I
HgeneCACNA1Dchr3:53804579chr3:52724960ENST00000350061+32481314_133313482162.0TransmembraneHelical%3B Name%3DS4 of repeat IV
HgeneCACNA1Dchr3:53804579chr3:52724960ENST00000350061+3248164_18313482162.0TransmembraneHelical%3B Name%3DS2 of repeat I
HgeneCACNA1Dchr3:53804579chr3:52724960ENST00000350061+3248196_21413482162.0TransmembraneHelical%3B Name%3DS3 of repeat I
HgeneCACNA1Dchr3:53804579chr3:52724960ENST00000350061+3248236_25413482162.0TransmembraneHelical%3B Name%3DS4 of repeat I
HgeneCACNA1Dchr3:53804579chr3:52724960ENST00000350061+3248274_29313482162.0TransmembraneHelical%3B Name%3DS5 of repeat I
HgeneCACNA1Dchr3:53804579chr3:52724960ENST00000350061+3248382_40613482162.0TransmembraneHelical%3B Name%3DS6 of repeat I
HgeneCACNA1Dchr3:53804579chr3:52724960ENST00000350061+3248524_54313482162.0TransmembraneHelical%3B Name%3DS1 of repeat II
HgeneCACNA1Dchr3:53804579chr3:52724960ENST00000350061+3248559_57713482162.0TransmembraneHelical%3B Name%3DS2 of repeat II
HgeneCACNA1Dchr3:53804579chr3:52724960ENST00000350061+3248586_60413482162.0TransmembraneHelical%3B Name%3DS3 of repeat II
HgeneCACNA1Dchr3:53804579chr3:52724960ENST00000350061+3248615_63313482162.0TransmembraneHelical%3B Name%3DS4 of repeat II
HgeneCACNA1Dchr3:53804579chr3:52724960ENST00000350061+3248653_67313482162.0TransmembraneHelical%3B Name%3DS5 of repeat II
HgeneCACNA1Dchr3:53804579chr3:52724960ENST00000350061+3248728_75213482162.0TransmembraneHelical%3B Name%3DS6 of repeat II
HgeneCACNA1Dchr3:53804579chr3:52724960ENST00000350061+3248887_90513482162.0TransmembraneHelical%3B Name%3DS1 of repeat III
HgeneCACNA1Dchr3:53804579chr3:52724960ENST00000350061+3248922_94113482162.0TransmembraneHelical%3B Name%3DS2 of repeat III
HgeneCACNA1Dchr3:53804579chr3:52724960ENST00000350061+3248954_97213482162.0TransmembraneHelical%3B Name%3DS3 of repeat III
HgeneCACNA1Dchr3:53804579chr3:52724960ENST00000350061+3248979_99813482162.0TransmembraneHelical%3B Name%3DS4 of repeat III
HgeneCACNA1Dchr3:53804579chr3:52724960ENST00000422281+31461018_103713332138.0TransmembraneHelical%3B Name%3DS5 of repeat III
HgeneCACNA1Dchr3:53804579chr3:52724960ENST00000422281+31461128_114813332138.0TransmembraneHelical%3B Name%3DS6 of repeat III
HgeneCACNA1Dchr3:53804579chr3:52724960ENST00000422281+31461206_122413332138.0TransmembraneHelical%3B Name%3DS1 of repeat IV
HgeneCACNA1Dchr3:53804579chr3:52724960ENST00000422281+31461240_125913332138.0TransmembraneHelical%3B Name%3DS2 of repeat IV
HgeneCACNA1Dchr3:53804579chr3:52724960ENST00000422281+31461267_128813332138.0TransmembraneHelical%3B Name%3DS3 of repeat IV
HgeneCACNA1Dchr3:53804579chr3:52724960ENST00000422281+3146127_14513332138.0TransmembraneHelical%3B Name%3DS1 of repeat I
HgeneCACNA1Dchr3:53804579chr3:52724960ENST00000422281+31461314_133313332138.0TransmembraneHelical%3B Name%3DS4 of repeat IV
HgeneCACNA1Dchr3:53804579chr3:52724960ENST00000422281+3146164_18313332138.0TransmembraneHelical%3B Name%3DS2 of repeat I
HgeneCACNA1Dchr3:53804579chr3:52724960ENST00000422281+3146196_21413332138.0TransmembraneHelical%3B Name%3DS3 of repeat I
HgeneCACNA1Dchr3:53804579chr3:52724960ENST00000422281+3146236_25413332138.0TransmembraneHelical%3B Name%3DS4 of repeat I
HgeneCACNA1Dchr3:53804579chr3:52724960ENST00000422281+3146274_29313332138.0TransmembraneHelical%3B Name%3DS5 of repeat I
HgeneCACNA1Dchr3:53804579chr3:52724960ENST00000422281+3146382_40613332138.0TransmembraneHelical%3B Name%3DS6 of repeat I
HgeneCACNA1Dchr3:53804579chr3:52724960ENST00000422281+3146524_54313332138.0TransmembraneHelical%3B Name%3DS1 of repeat II
HgeneCACNA1Dchr3:53804579chr3:52724960ENST00000422281+3146559_57713332138.0TransmembraneHelical%3B Name%3DS2 of repeat II
HgeneCACNA1Dchr3:53804579chr3:52724960ENST00000422281+3146586_60413332138.0TransmembraneHelical%3B Name%3DS3 of repeat II
HgeneCACNA1Dchr3:53804579chr3:52724960ENST00000422281+3146615_63313332138.0TransmembraneHelical%3B Name%3DS4 of repeat II
HgeneCACNA1Dchr3:53804579chr3:52724960ENST00000422281+3146653_67313332138.0TransmembraneHelical%3B Name%3DS5 of repeat II
HgeneCACNA1Dchr3:53804579chr3:52724960ENST00000422281+3146728_75213332138.0TransmembraneHelical%3B Name%3DS6 of repeat II
HgeneCACNA1Dchr3:53804579chr3:52724960ENST00000422281+3146887_90513332138.0TransmembraneHelical%3B Name%3DS1 of repeat III
HgeneCACNA1Dchr3:53804579chr3:52724960ENST00000422281+3146922_94113332138.0TransmembraneHelical%3B Name%3DS2 of repeat III
HgeneCACNA1Dchr3:53804579chr3:52724960ENST00000422281+3146954_97213332138.0TransmembraneHelical%3B Name%3DS3 of repeat III
HgeneCACNA1Dchr3:53804579chr3:52724960ENST00000422281+3146979_99813332138.0TransmembraneHelical%3B Name%3DS4 of repeat III
HgeneCACNA1Dchr3:53804579chr3:52724961ENST00000288139+33491018_103713682182.0TransmembraneHelical%3B Name%3DS5 of repeat III
HgeneCACNA1Dchr3:53804579chr3:52724961ENST00000288139+33491128_114813682182.0TransmembraneHelical%3B Name%3DS6 of repeat III
HgeneCACNA1Dchr3:53804579chr3:52724961ENST00000288139+33491206_122413682182.0TransmembraneHelical%3B Name%3DS1 of repeat IV
HgeneCACNA1Dchr3:53804579chr3:52724961ENST00000288139+33491240_125913682182.0TransmembraneHelical%3B Name%3DS2 of repeat IV
HgeneCACNA1Dchr3:53804579chr3:52724961ENST00000288139+33491267_128813682182.0TransmembraneHelical%3B Name%3DS3 of repeat IV
HgeneCACNA1Dchr3:53804579chr3:52724961ENST00000288139+3349127_14513682182.0TransmembraneHelical%3B Name%3DS1 of repeat I
HgeneCACNA1Dchr3:53804579chr3:52724961ENST00000288139+33491314_133313682182.0TransmembraneHelical%3B Name%3DS4 of repeat IV
HgeneCACNA1Dchr3:53804579chr3:52724961ENST00000288139+3349164_18313682182.0TransmembraneHelical%3B Name%3DS2 of repeat I
HgeneCACNA1Dchr3:53804579chr3:52724961ENST00000288139+3349196_21413682182.0TransmembraneHelical%3B Name%3DS3 of repeat I
HgeneCACNA1Dchr3:53804579chr3:52724961ENST00000288139+3349236_25413682182.0TransmembraneHelical%3B Name%3DS4 of repeat I
HgeneCACNA1Dchr3:53804579chr3:52724961ENST00000288139+3349274_29313682182.0TransmembraneHelical%3B Name%3DS5 of repeat I
HgeneCACNA1Dchr3:53804579chr3:52724961ENST00000288139+3349382_40613682182.0TransmembraneHelical%3B Name%3DS6 of repeat I
HgeneCACNA1Dchr3:53804579chr3:52724961ENST00000288139+3349524_54313682182.0TransmembraneHelical%3B Name%3DS1 of repeat II
HgeneCACNA1Dchr3:53804579chr3:52724961ENST00000288139+3349559_57713682182.0TransmembraneHelical%3B Name%3DS2 of repeat II
HgeneCACNA1Dchr3:53804579chr3:52724961ENST00000288139+3349586_60413682182.0TransmembraneHelical%3B Name%3DS3 of repeat II
HgeneCACNA1Dchr3:53804579chr3:52724961ENST00000288139+3349615_63313682182.0TransmembraneHelical%3B Name%3DS4 of repeat II
HgeneCACNA1Dchr3:53804579chr3:52724961ENST00000288139+3349653_67313682182.0TransmembraneHelical%3B Name%3DS5 of repeat II
HgeneCACNA1Dchr3:53804579chr3:52724961ENST00000288139+3349728_75213682182.0TransmembraneHelical%3B Name%3DS6 of repeat II
HgeneCACNA1Dchr3:53804579chr3:52724961ENST00000288139+3349887_90513682182.0TransmembraneHelical%3B Name%3DS1 of repeat III
HgeneCACNA1Dchr3:53804579chr3:52724961ENST00000288139+3349922_94113682182.0TransmembraneHelical%3B Name%3DS2 of repeat III
HgeneCACNA1Dchr3:53804579chr3:52724961ENST00000288139+3349954_97213682182.0TransmembraneHelical%3B Name%3DS3 of repeat III
HgeneCACNA1Dchr3:53804579chr3:52724961ENST00000288139+3349979_99813682182.0TransmembraneHelical%3B Name%3DS4 of repeat III
HgeneCACNA1Dchr3:53804579chr3:52724961ENST00000350061+32481018_103713482162.0TransmembraneHelical%3B Name%3DS5 of repeat III
HgeneCACNA1Dchr3:53804579chr3:52724961ENST00000350061+32481128_114813482162.0TransmembraneHelical%3B Name%3DS6 of repeat III
HgeneCACNA1Dchr3:53804579chr3:52724961ENST00000350061+32481206_122413482162.0TransmembraneHelical%3B Name%3DS1 of repeat IV
HgeneCACNA1Dchr3:53804579chr3:52724961ENST00000350061+32481240_125913482162.0TransmembraneHelical%3B Name%3DS2 of repeat IV
HgeneCACNA1Dchr3:53804579chr3:52724961ENST00000350061+32481267_128813482162.0TransmembraneHelical%3B Name%3DS3 of repeat IV
HgeneCACNA1Dchr3:53804579chr3:52724961ENST00000350061+3248127_14513482162.0TransmembraneHelical%3B Name%3DS1 of repeat I
HgeneCACNA1Dchr3:53804579chr3:52724961ENST00000350061+32481314_133313482162.0TransmembraneHelical%3B Name%3DS4 of repeat IV
HgeneCACNA1Dchr3:53804579chr3:52724961ENST00000350061+3248164_18313482162.0TransmembraneHelical%3B Name%3DS2 of repeat I
HgeneCACNA1Dchr3:53804579chr3:52724961ENST00000350061+3248196_21413482162.0TransmembraneHelical%3B Name%3DS3 of repeat I
HgeneCACNA1Dchr3:53804579chr3:52724961ENST00000350061+3248236_25413482162.0TransmembraneHelical%3B Name%3DS4 of repeat I
HgeneCACNA1Dchr3:53804579chr3:52724961ENST00000350061+3248274_29313482162.0TransmembraneHelical%3B Name%3DS5 of repeat I
HgeneCACNA1Dchr3:53804579chr3:52724961ENST00000350061+3248382_40613482162.0TransmembraneHelical%3B Name%3DS6 of repeat I
HgeneCACNA1Dchr3:53804579chr3:52724961ENST00000350061+3248524_54313482162.0TransmembraneHelical%3B Name%3DS1 of repeat II
HgeneCACNA1Dchr3:53804579chr3:52724961ENST00000350061+3248559_57713482162.0TransmembraneHelical%3B Name%3DS2 of repeat II
HgeneCACNA1Dchr3:53804579chr3:52724961ENST00000350061+3248586_60413482162.0TransmembraneHelical%3B Name%3DS3 of repeat II
HgeneCACNA1Dchr3:53804579chr3:52724961ENST00000350061+3248615_63313482162.0TransmembraneHelical%3B Name%3DS4 of repeat II
HgeneCACNA1Dchr3:53804579chr3:52724961ENST00000350061+3248653_67313482162.0TransmembraneHelical%3B Name%3DS5 of repeat II
HgeneCACNA1Dchr3:53804579chr3:52724961ENST00000350061+3248728_75213482162.0TransmembraneHelical%3B Name%3DS6 of repeat II
HgeneCACNA1Dchr3:53804579chr3:52724961ENST00000350061+3248887_90513482162.0TransmembraneHelical%3B Name%3DS1 of repeat III
HgeneCACNA1Dchr3:53804579chr3:52724961ENST00000350061+3248922_94113482162.0TransmembraneHelical%3B Name%3DS2 of repeat III
HgeneCACNA1Dchr3:53804579chr3:52724961ENST00000350061+3248954_97213482162.0TransmembraneHelical%3B Name%3DS3 of repeat III
HgeneCACNA1Dchr3:53804579chr3:52724961ENST00000350061+3248979_99813482162.0TransmembraneHelical%3B Name%3DS4 of repeat III
HgeneCACNA1Dchr3:53804579chr3:52724961ENST00000422281+31461018_103713332138.0TransmembraneHelical%3B Name%3DS5 of repeat III
HgeneCACNA1Dchr3:53804579chr3:52724961ENST00000422281+31461128_114813332138.0TransmembraneHelical%3B Name%3DS6 of repeat III
HgeneCACNA1Dchr3:53804579chr3:52724961ENST00000422281+31461206_122413332138.0TransmembraneHelical%3B Name%3DS1 of repeat IV
HgeneCACNA1Dchr3:53804579chr3:52724961ENST00000422281+31461240_125913332138.0TransmembraneHelical%3B Name%3DS2 of repeat IV
HgeneCACNA1Dchr3:53804579chr3:52724961ENST00000422281+31461267_128813332138.0TransmembraneHelical%3B Name%3DS3 of repeat IV
HgeneCACNA1Dchr3:53804579chr3:52724961ENST00000422281+3146127_14513332138.0TransmembraneHelical%3B Name%3DS1 of repeat I
HgeneCACNA1Dchr3:53804579chr3:52724961ENST00000422281+31461314_133313332138.0TransmembraneHelical%3B Name%3DS4 of repeat IV
HgeneCACNA1Dchr3:53804579chr3:52724961ENST00000422281+3146164_18313332138.0TransmembraneHelical%3B Name%3DS2 of repeat I
HgeneCACNA1Dchr3:53804579chr3:52724961ENST00000422281+3146196_21413332138.0TransmembraneHelical%3B Name%3DS3 of repeat I
HgeneCACNA1Dchr3:53804579chr3:52724961ENST00000422281+3146236_25413332138.0TransmembraneHelical%3B Name%3DS4 of repeat I
HgeneCACNA1Dchr3:53804579chr3:52724961ENST00000422281+3146274_29313332138.0TransmembraneHelical%3B Name%3DS5 of repeat I
HgeneCACNA1Dchr3:53804579chr3:52724961ENST00000422281+3146382_40613332138.0TransmembraneHelical%3B Name%3DS6 of repeat I
HgeneCACNA1Dchr3:53804579chr3:52724961ENST00000422281+3146524_54313332138.0TransmembraneHelical%3B Name%3DS1 of repeat II
HgeneCACNA1Dchr3:53804579chr3:52724961ENST00000422281+3146559_57713332138.0TransmembraneHelical%3B Name%3DS2 of repeat II
HgeneCACNA1Dchr3:53804579chr3:52724961ENST00000422281+3146586_60413332138.0TransmembraneHelical%3B Name%3DS3 of repeat II
HgeneCACNA1Dchr3:53804579chr3:52724961ENST00000422281+3146615_63313332138.0TransmembraneHelical%3B Name%3DS4 of repeat II
HgeneCACNA1Dchr3:53804579chr3:52724961ENST00000422281+3146653_67313332138.0TransmembraneHelical%3B Name%3DS5 of repeat II
HgeneCACNA1Dchr3:53804579chr3:52724961ENST00000422281+3146728_75213332138.0TransmembraneHelical%3B Name%3DS6 of repeat II
HgeneCACNA1Dchr3:53804579chr3:52724961ENST00000422281+3146887_90513332138.0TransmembraneHelical%3B Name%3DS1 of repeat III
HgeneCACNA1Dchr3:53804579chr3:52724961ENST00000422281+3146922_94113332138.0TransmembraneHelical%3B Name%3DS2 of repeat III
HgeneCACNA1Dchr3:53804579chr3:52724961ENST00000422281+3146954_97213332138.0TransmembraneHelical%3B Name%3DS3 of repeat III
HgeneCACNA1Dchr3:53804579chr3:52724961ENST00000422281+3146979_99813332138.0TransmembraneHelical%3B Name%3DS4 of repeat III

check button Subcellular localization prediction of the transmembrane domain retained fusion proteins
* We used DeepLoc 1.0. The order of the X-axis of the barplot is as follows: Entry_ID, Localization, Type, Nucleus, Cytoplasm, Extracellular, Mitochondrion, Cell_membrane, Endoplasmic_reticulum, Plastid, Golgi.apparatus, Lysosome.Vacuole, Peroxisome. Y-axis is the output score of DeepLoc. Clicking the image will open a new tab with a large image.
HgeneHchrHbpHenstTgeneTchrTbpTenstDeepLoc result
CACNA1Dchr353804579ENST00000288139GNL3chr352724960ENST00000394799
CACNA1Dchr353804579ENST00000350061GNL3chr352724960ENST00000394799
CACNA1Dchr353804579ENST00000422281GNL3chr352724960ENST00000394799
CACNA1Dchr353804579ENST00000540742GNL3chr352724960ENST00000394799

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Related Drugs to CACNA1D-GNL3

check button Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDrugSourcePMID

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Related Diseases to CACNA1D-GNL3

check button Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDiseaseSourcePMID

check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource