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Fusion Protein:DIS3L2-INPP5D

Fusion Gene and Fusion Protein Summary

Fusion gene summary

Fusion partner gene information	Fusion gene name: DIS3L2-INPP5D
	FusionPDB ID: 22905
	FusionGDB2.0 ID: 22905
		Hgene	Tgene
	Gene symbol	DIS3L2	INPP5D
	Gene ID	129563	3635
	Gene name	DIS3 like 3'-5' exoribonuclease 2	inositol polyphosphate-5-phosphatase D
	Synonyms	FAM6A\|PRLMNS\|hDIS3L2	SHIP\|SHIP-1\|SHIP1\|SIP-145\|hp51CN\|p150Ship
	Cytomap	2q37.1	2q37.1
	Type of gene	protein-coding	protein-coding
	Description	DIS3-like exonuclease 2DIS3 mitotic control homolog-like 2family with sequence similarity 6, member A	phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1SH2 domain-containing inositol 5'-phosphatase 1inositol polyphosphate-5-phosphatase, 145kDinositol polyphosphate-5-phosphatase, 145kDaphosphatidylinositol 4,5-bisphosphate 5-phosphatasesignaling
	Modification date	20200313	20200313
	UniProtAcc	Q8IYB7 Main function of 5'-partner protein: FUNCTION: 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mitosis, and negatively regulates cell proliferation. {ECO:0000255\|HAMAP-Rule:MF_03045, ECO:0000269\|PubMed:23756462, ECO:0000269\|PubMed:24141620}.	Q92835 Main function of 5'-partner protein: FUNCTION: Phosphatidylinositol (PtdIns) phosphatase that specifically hydrolyzes the 5-phosphate of phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3) to produce PtdIns(3,4)P2, thereby negatively regulating the PI3K (phosphoinositide 3-kinase) pathways (PubMed:8723348, PubMed:10764818, PubMed:8769125). Able also to hydrolyzes the 5-phosphate of phosphatidylinositol-4,5-bisphosphate (PtdIns(4,5)P3) and inositol 1,3,4,5-tetrakisphosphate (PubMed:9108392, PubMed:10764818, PubMed:8769125). Acts as a negative regulator of B-cell antigen receptor signaling. Mediates signaling from the FC-gamma-RIIB receptor (FCGR2B), playing a central role in terminating signal transduction from activating immune/hematopoietic cell receptor systems. Acts as a negative regulator of myeloid cell proliferation/survival and chemotaxis, mast cell degranulation, immune cells homeostasis, integrin alpha-IIb/beta-3 signaling in platelets and JNK signaling in B-cells. Regulates proliferation of osteoclast precursors, macrophage programming, phagocytosis and activation and is required for endotoxin tolerance. Involved in the control of cell-cell junctions, CD32a signaling in neutrophils and modulation of EGF-induced phospholipase C activity (PubMed:16682172). Key regulator of neutrophil migration, by governing the formation of the leading edge and polarization required for chemotaxis. Modulates FCGR3/CD16-mediated cytotoxicity in NK cells. Mediates the activin/TGF-beta-induced apoptosis through its Smad-dependent expression. {ECO:0000269\|PubMed:10764818, ECO:0000269\|PubMed:12421919, ECO:0000269\|PubMed:16682172, ECO:0000269\|PubMed:8723348, ECO:0000269\|PubMed:8769125, ECO:0000269\|PubMed:9108392}.
Ensembl transtripts involved in fusion gene	ENST ids	ENST00000273009, ENST00000325385, ENST00000409307, ENST00000360410, ENST00000409401, ENST00000470087,	ENST00000474278, ENST00000538935, ENST00000359570, ENST00000450745, ENST00000455936,
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)	* DoF score	27 X 9 X 12=2916	8 X 10 X 5=400
	# samples	25	10
	** MAII score	log2(25/2916*10)=-3.54399071966485 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(10/400*10)=-2 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Fusion gene context	PubMed: DIS3L2 [Title/Abstract] AND INPP5D [Title/Abstract] AND fusion [Title/Abstract]
Fusion neoantigen context	PubMed: DIS3L2 [Title/Abstract] AND INPP5D [Title/Abstract] AND neoantigen [Title/Abstract]
Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)	DIS3L2(233103355)-INPP5D(234054804), # samples:1
Anticipated loss of major functional domain due to fusion event.	DIS3L2-INPP5D seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. DIS3L2-INPP5D seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. DIS3L2-INPP5D seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. DIS3L2-INPP5D seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. DIS3L2-INPP5D seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Hgene	DIS3L2	GO:0010587	miRNA catabolic process	24141620

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr2:233103355/chr2:234054804)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Retention analysis results of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features, are available here.

Fusion gene breakpoints across DIS3L2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across INPP5D (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

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Fusion Amino Acid Sequences

Fusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000273009	DIS3L2	chr2	233103355	+	ENST00000359570	INPP5D	chr2	234054804	+	5942	1931	578	4747	1389
ENST00000273009	DIS3L2	chr2	233103355	+	ENST00000450745	INPP5D	chr2	234054804	+	5942	1931	578	4747	1389
ENST00000273009	DIS3L2	chr2	233103355	+	ENST00000455936	INPP5D	chr2	234054804	+	5946	1931	578	4750	1390
ENST00000325385	DIS3L2	chr2	233103355	+	ENST00000359570	INPP5D	chr2	234054804	+	5604	1593	240	4409	1389
ENST00000325385	DIS3L2	chr2	233103355	+	ENST00000450745	INPP5D	chr2	234054804	+	5604	1593	240	4409	1389
ENST00000325385	DIS3L2	chr2	233103355	+	ENST00000455936	INPP5D	chr2	234054804	+	5608	1593	240	4412	1390
ENST00000409307	DIS3L2	chr2	233103355	+	ENST00000359570	INPP5D	chr2	234054804	+	5328	1317	0	4133	1377
ENST00000409307	DIS3L2	chr2	233103355	+	ENST00000450745	INPP5D	chr2	234054804	+	5328	1317	0	4133	1377
ENST00000409307	DIS3L2	chr2	233103355	+	ENST00000455936	INPP5D	chr2	234054804	+	5332	1317	0	4136	1378

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000273009	ENST00000359570	DIS3L2	chr2	233103355	+	INPP5D	chr2	234054804	+	0.003918701	0.9960813
ENST00000273009	ENST00000450745	DIS3L2	chr2	233103355	+	INPP5D	chr2	234054804	+	0.003918701	0.9960813
ENST00000273009	ENST00000455936	DIS3L2	chr2	233103355	+	INPP5D	chr2	234054804	+	0.004120413	0.99587953
ENST00000325385	ENST00000359570	DIS3L2	chr2	233103355	+	INPP5D	chr2	234054804	+	0.00261378	0.9973863
ENST00000325385	ENST00000450745	DIS3L2	chr2	233103355	+	INPP5D	chr2	234054804	+	0.00261378	0.9973863
ENST00000325385	ENST00000455936	DIS3L2	chr2	233103355	+	INPP5D	chr2	234054804	+	0.002753305	0.99724674
ENST00000409307	ENST00000359570	DIS3L2	chr2	233103355	+	INPP5D	chr2	234054804	+	0.001779036	0.998221
ENST00000409307	ENST00000450745	DIS3L2	chr2	233103355	+	INPP5D	chr2	234054804	+	0.001779036	0.998221
ENST00000409307	ENST00000455936	DIS3L2	chr2	233103355	+	INPP5D	chr2	234054804	+	0.001882815	0.9981172

Predicted full-length fusion amino acid sequences. For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among all the predicted ones.

Get the fusion protein sequences from here.

Fusion protein sequence information is available in the fasta format.
>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

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Fusion Protein Breakpoint Sequences for DIS3L2-INPP5D

+/-13 AA sequence from the breakpoints of the fusion protein sequences.

Hgene	Hchr	Hbp	Tgene	Tchr	Tbp	Length(fusion protein)	BP in fusion protein	Peptide
DIS3L2	chr2	233103355	INPP5D	chr2	234054804	1317	439	AAERATSVYLVQKQVPGEANPINMVS
DIS3L2	chr2	233103355	INPP5D	chr2	234054804	1317	439	AAERATSVYLVQKVPGEANPINMVSK
DIS3L2	chr2	233103355	INPP5D	chr2	234054804	1593	451	AAERATSVYLVQKQVPGEANPINMVS
DIS3L2	chr2	233103355	INPP5D	chr2	234054804	1593	451	AAERATSVYLVQKVPGEANPINMVSK
DIS3L2	chr2	233103355	INPP5D	chr2	234054804	1931	451	AAERATSVYLVQKQVPGEANPINMVS
DIS3L2	chr2	233103355	INPP5D	chr2	234054804	1931	451	AAERATSVYLVQKVPGEANPINMVSK

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Potential FusionNeoAntigen Information of DIS3L2-INPP5D in HLA I

Multiple sequence alignments of the potential FusionNeoAntigens per fusion breakpoints. If the MSA is empty, then it means that there were predicted fusion neoantigens in this fusion breakpoint, but those predicted fusion neoantigens were not across the breakpoint, which is not fusion-specific.

DIS3L2-INPP5D_233103355_234054804.msa

Potential FusionNeoAntigen Information
* We used NetMHCpan v4.1 (%rank<0.5) and deepHLApan v1.1 (immunogenic score>0.5)

Fusion gene	Hchr	Hbp	Tgene	Tchr	Tbp	HLA I	FusionNeoAntigen peptide	Binding score	Immunogenic score	Neoantigen start (at BP 13)	Neoantigen end (at BP 13)
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	HLA-B52:01	SVYLVQKV	0.9942	0.9745	6	14
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	HLA-A30:08	SVYLVQKQV	0.8743	0.6683	6	15
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	HLA-A02:21	SVYLVQKQV	0.8032	0.5529	6	15
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	HLA-B52:01	SVYLVQKQV	0.6211	0.9707	6	15
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	HLA-B13:02	SVYLVQKQV	0.5272	0.6742	6	15
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	HLA-A02:13	YLVQKVPGEA	0.9211	0.5733	8	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	HLA-B13:02	KQVPGEANPI	0.8434	0.8461	12	22
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	HLA-A02:38	YLVQKVPGEA	0.8278	0.5031	8	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	HLA-B51:07	SVYLVQKV	0.9939	0.9088	6	14
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	HLA-C15:06	SVYLVQKQV	0.997	0.7448	6	15
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	HLA-C15:04	SVYLVQKQV	0.9957	0.7364	6	15
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	HLA-C12:04	TSVYLVQKV	0.9826	0.9779	5	14
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	HLA-C06:03	TSVYLVQKV	0.9818	0.9645	5	14
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	HLA-C06:03	SVYLVQKQV	0.9536	0.9685	6	15
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	HLA-C12:04	SVYLVQKQV	0.9471	0.9792	6	15
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	HLA-B15:04	VQKQVPGEA	0.9222	0.8644	10	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	HLA-C02:06	SVYLVQKQV	0.8529	0.8787	6	15
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	HLA-C02:06	TSVYLVQKV	0.7675	0.9189	5	14
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	HLA-B51:07	SVYLVQKQV	0.6483	0.9023	6	15
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	HLA-C01:17	KVPGEANPI	0.0678	0.8761	12	21
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	HLA-C01:30	KVPGEANPI	0.0099	0.9035	12	21
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	HLA-C15:02	TSVYLVQKV	0.9997	0.7407	5	14
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	HLA-C15:05	TSVYLVQKV	0.9996	0.791	5	14
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	HLA-C15:02	SVYLVQKQV	0.998	0.7122	6	15
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	HLA-C15:05	SVYLVQKQV	0.997	0.7721	6	15
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	HLA-C15:09	SVYLVQKQV	0.9957	0.7364	6	15
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	HLA-A69:01	TSVYLVQKV	0.9955	0.6913	5	14
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	HLA-A69:01	SVYLVQKQV	0.9594	0.6116	6	15
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	HLA-A02:06	SVYLVQKQV	0.8032	0.5529	6	15
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	HLA-C06:08	SVYLVQKQV	0.7913	0.9612	6	15
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	HLA-C01:02	KVPGEANPI	0.0352	0.8758	12	21
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	HLA-C01:03	KVPGEANPI	0.0331	0.8338	12	21
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	HLA-A02:03	YLVQKVPGEA	0.9832	0.5564	8	18

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Potential FusionNeoAntigen Information of DIS3L2-INPP5D in HLA II

DIS3L2-INPP5D_233103355_234054804.msa

Potential FusionNeoAntigen Information
* We used NetMHCIIpan v4.1 (%rank<0.5).

Fusion gene	Hchr	Hbp	Tgene	Tchr	Tbp	HLA II	FusionNeoAntigen peptide	Neoantigen start (at BP 13)	Neoantigen end (at BP 13)
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0401	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0405	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0405	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0405	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0405	SVYLVQKVPGEANPI	6	21
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0407	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0407	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0409	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0409	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0409	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0409	SVYLVQKVPGEANPI	6	21
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0417	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0417	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0417	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0419	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0424	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0424	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0424	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0429	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0429	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0429	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0429	SVYLVQKVPGEANPI	6	21
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0430	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0430	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0430	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0430	SVYLVQKVPGEANPI	6	21
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0431	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0433	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0434	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0434	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0435	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0435	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0438	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0438	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0443	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0445	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0445	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0445	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0445	SVYLVQKVPGEANPI	6	21
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0447	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0447	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0448	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0448	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0448	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0448	SVYLVQKVPGEANPI	6	21
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0454	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0457	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0457	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0457	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0457	SVYLVQKVPGEANPI	6	21
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0461	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0462	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0462	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0462	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0463	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0464	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0464	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0472	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0474	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0475	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0476	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0477	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0477	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0477	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0477	SVYLVQKVPGEANPI	6	21
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0480	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0480	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0480	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0480	SVYLVQKVPGEANPI	6	21
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0482	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0482	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0483	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0483	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0483	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0483	SVYLVQKVPGEANPI	6	21
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0484	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0484	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0484	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0484	SVYLVQKVPGEANPI	6	21
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0486	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0486	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0487	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0487	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0487	SVYLVQKVPGEANPI	6	21
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0487	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0489	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0489	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0489	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0489	SVYLVQKVPGEANPI	6	21
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0801	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0801	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0801	TSVYLVQKQVPGEAN	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0802	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0802	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0802	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0803	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0803	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0803	TSVYLVQKQVPGEAN	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0804	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0804	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0804	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0804	ERATSVYLVQKVPGE	2	17
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0804	SVYLVQKVPGEANPI	6	21
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0805	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0805	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0806	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0806	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0806	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0806	SVYLVQKQVPGEANP	6	21
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0806	TSVYLVQKQVPGEAN	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0807	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0807	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0808	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0808	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0809	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0809	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0809	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0810	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0810	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0810	SVYLVQKQVPGEANP	6	21
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0811	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0811	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0812	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0812	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0813	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0813	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0813	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0813	TSVYLVQKQVPGEAN	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0814	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0814	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0814	TSVYLVQKQVPGEAN	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0815	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0815	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0815	TSVYLVQKQVPGEAN	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0816	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0816	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0816	TSVYLVQKQVPGEAN	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0818	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0818	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0820	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0820	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0820	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0820	ERATSVYLVQKVPGE	2	17
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0821	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0821	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0821	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0822	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0822	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0822	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0822	SVYLVQKQVPGEANP	6	21
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0822	TSVYLVQKQVPGEAN	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0823	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0823	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0823	TSVYLVQKQVPGEAN	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0824	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0824	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0824	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0824	TSVYLVQKQVPGEAN	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0824	ATSVYLVQKQVPGEA	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0826	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0826	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0826	TSVYLVQKQVPGEAN	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0827	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0827	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0827	TSVYLVQKQVPGEAN	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0828	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0828	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0828	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0828	ERATSVYLVQKVPGE	2	17
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0829	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0829	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0830	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0830	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0830	TSVYLVQKQVPGEAN	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0831	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0831	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0831	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0831	ERATSVYLVQKVPGE	2	17
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0832	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0832	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0832	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0832	TSVYLVQKQVPGEAN	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0833	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0833	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0833	TSVYLVQKQVPGEAN	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0835	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0835	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0835	TSVYLVQKQVPGEAN	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0836	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0836	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0836	TSVYLVQKQVPGEAN	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0837	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0837	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0838	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0838	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0838	TSVYLVQKQVPGEAN	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0839	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0839	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0839	TSVYLVQKQVPGEAN	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0840	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-0840	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1001	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1003	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1101	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1101	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1103	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1104	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1104	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1104	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1104	ERATSVYLVQKVPGE	2	17
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1105	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1105	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1105	TSVYLVQKQVPGEAN	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1106	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1106	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1106	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1106	ERATSVYLVQKVPGE	2	17
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1108	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1108	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1109	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1109	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1110	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1110	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1112	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1112	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1113	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1113	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1115	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1115	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1117	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1117	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1118	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1118	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1118	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1118	ERATSVYLVQKVPGE	2	17
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1119	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1124	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1124	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1125	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1125	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1125	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1125	ERATSVYLVQKVPGE	2	17
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1127	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1127	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1128	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1128	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1129	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1129	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1130	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1130	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1130	TSVYLVQKQVPGEAN	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1130	ATSVYLVQKQVPGEA	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1131	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1132	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1132	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1133	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1133	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1134	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1134	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1135	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1135	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1135	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1135	ERATSVYLVQKVPGE	2	17
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1137	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1137	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1138	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1138	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1138	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1138	ERATSVYLVQKVPGE	2	17
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1139	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1139	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1141	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1141	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1142	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1142	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1142	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1142	ERATSVYLVQKVPGE	2	17
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1143	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1143	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1143	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1143	ERATSVYLVQKVPGE	2	17
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1144	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1144	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1144	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1144	ERATSVYLVQKVPGE	2	17
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1145	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1146	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1146	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1146	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1146	ERATSVYLVQKVPGE	2	17
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1147	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1147	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1147	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1147	ERATSVYLVQKVPGE	2	17
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1148	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1149	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1149	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1150	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1150	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1150	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1150	ERATSVYLVQKVPGE	2	17
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1151	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1151	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1152	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1152	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1154	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1154	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1154	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1154	ERATSVYLVQKVPGE	2	17
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1156	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1156	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1156	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1156	ERATSVYLVQKVPGE	2	17
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1157	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1157	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1157	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1158	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1158	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1158	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1158	ERATSVYLVQKVPGE	2	17
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1159	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1160	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1160	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1160	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1160	ERATSVYLVQKVPGE	2	17
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1161	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1161	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1162	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1162	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1163	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1164	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1166	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1166	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1167	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1167	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1167	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1167	ERATSVYLVQKVPGE	2	17
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1169	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1169	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1172	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1172	TSVYLVQKQVPGEAN	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1172	ATSVYLVQKQVPGEA	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1174	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1174	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1175	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1175	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1176	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1177	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1177	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1177	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1177	ERATSVYLVQKVPGE	2	17
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1178	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1178	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1178	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1178	ERATSVYLVQKVPGE	2	17
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1180	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1180	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1181	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1181	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1182	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1183	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1183	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1183	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1183	ERATSVYLVQKVPGE	2	17
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1184	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1184	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1184	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1184	ERATSVYLVQKVPGE	2	17
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1185	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1187	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1187	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1188	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1188	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1188	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1188	ERATSVYLVQKVPGE	2	17
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1189	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1189	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1190	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1190	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1191	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1191	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1192	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1192	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1192	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1193	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1194	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1194	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1195	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1195	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1196	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1196	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1204	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1209	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1216	TSVYLVQKQVPGEAN	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1216	ATSVYLVQKQVPGEA	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1305	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1305	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1306	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1306	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1306	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1306	ERATSVYLVQKVPGE	2	17
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1307	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1307	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1308	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1309	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1309	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-13100	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-13101	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1310	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1311	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1311	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1311	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1311	ERATSVYLVQKVPGE	2	17
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1312	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1313	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1313	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1314	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1314	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1318	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1318	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1318	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1318	ERATSVYLVQKVPGE	2	17
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1324	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1326	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1326	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1326	TSVYLVQKQVPGEAN	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1337	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1342	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1342	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1342	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1342	ERATSVYLVQKVPGE	2	17
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1344	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1344	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1346	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1347	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1347	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1349	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1350	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1350	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1355	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1355	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1356	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1356	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1358	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1358	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1360	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1360	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1362	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1362	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1370	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1372	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1377	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1381	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1382	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1384	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1385	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1386	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1389	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1402	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1402	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1403	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1405	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1405	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1406	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1406	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1406	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1408	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1408	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1409	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1409	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1409	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1411	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1411	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1412	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1412	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1412	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1413	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1413	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1413	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1415	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1415	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1415	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1415	ERATSVYLVQKVPGE	2	17
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1415	SVYLVQKVPGEANPI	6	21
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1417	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1417	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1418	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1418	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1420	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1420	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1420	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1421	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1421	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1422	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1423	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1423	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1424	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1425	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1427	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1427	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1427	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1429	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1429	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1430	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1431	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1433	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1433	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1434	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1434	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1437	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1437	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1440	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1441	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1441	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1443	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1443	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1445	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1445	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1446	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1446	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1446	TSVYLVQKQVPGEAN	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1446	ATSVYLVQKQVPGEA	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1449	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1451	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1452	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1452	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1453	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1456	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1456	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1459	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1459	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1463	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1463	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1464	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1464	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1465	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1467	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1469	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1472	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1472	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1473	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1473	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1473	ERATSVYLVQKVPGE	2	17
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1474	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1474	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1477	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1478	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1478	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1480	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1480	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1480	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1481	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1481	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1483	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1483	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1483	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1484	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1484	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1484	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1484	ERATSVYLVQKVPGE	2	17
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1485	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1485	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1489	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1489	TSVYLVQKVPGEANP	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1491	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1491	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1494	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1494	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1496	ATSVYLVQKVPGEAN	4	19
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB1-1496	RATSVYLVQKVPGEA	3	18
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB5-0102	TSVYLVQKQVPGEAN	5	20
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	1931	DRB5-0108N	TSVYLVQKQVPGEAN	5	20

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Fusion breakpoint peptide structures of DIS3L2-INPP5D

3D structures of the fusion breakpoint peptide of 14AA sequence that have potential fusion neoantigens
* The minimum length of the amino acid sequence in RoseTTAFold is 14AA. Here, we predicted the 14AA fusion protein breakpoint sequence not the fusion neoantigen peptide, which is shorter than 14 AA.

File name	BPseq	Hgene	Tgene	Hchr	Hbp	Tchr	Tbp	AAlen
9175	SVYLVQKQVPGEAN	DIS3L2	INPP5D	chr2	233103355	chr2	234054804	1931

File name	BPseq	Hgene	Tgene	Hchr	Hbp	Tchr	Tbp	AAlen
9176	SVYLVQKVPGEANP	DIS3L2	INPP5D	chr2	233103355	chr2	234054804	1931

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Filtering FusionNeoAntigens Through Checking the Interaction with HLAs in 3D of DIS3L2-INPP5D

Virtual screening between 25 HLAs (from PDB) and FusionNeoAntigens
* We used Glide to predict the interaction between HLAs and neoantigens.

HLA allele	PDB ID	File name	BPseq	Docking score	Glide score
HLA-B14:02	3BVN	9175	SVYLVQKQVPGEAN	-7.9962	-8.1096
HLA-B14:02	3BVN	9175	SVYLVQKQVPGEAN	-5.70842	-6.74372
HLA-B52:01	3W39	9175	SVYLVQKQVPGEAN	-6.83737	-6.95077
HLA-B52:01	3W39	9175	SVYLVQKQVPGEAN	-4.4836	-5.5189
HLA-A11:01	4UQ2	9175	SVYLVQKQVPGEAN	-10.0067	-10.1201
HLA-A11:01	4UQ2	9175	SVYLVQKQVPGEAN	-9.03915	-10.0745
HLA-A24:02	5HGA	9175	SVYLVQKQVPGEAN	-6.56204	-6.67544
HLA-A24:02	5HGA	9175	SVYLVQKQVPGEAN	-5.42271	-6.45801
HLA-B44:05	3DX8	9175	SVYLVQKQVPGEAN	-7.85648	-8.89178
HLA-B44:05	3DX8	9175	SVYLVQKQVPGEAN	-5.3978	-5.5112
HLA-A02:01	6TDR	9175	SVYLVQKQVPGEAN	-3.37154	-4.40684
HLA-B14:02	3BVN	9176	SVYLVQKVPGEANP	-7.9962	-8.1096
HLA-B14:02	3BVN	9176	SVYLVQKVPGEANP	-5.70842	-6.74372
HLA-B52:01	3W39	9176	SVYLVQKVPGEANP	-6.83737	-6.95077
HLA-B52:01	3W39	9176	SVYLVQKVPGEANP	-4.4836	-5.5189
HLA-A11:01	4UQ2	9176	SVYLVQKVPGEANP	-10.0067	-10.1201
HLA-A11:01	4UQ2	9176	SVYLVQKVPGEANP	-9.03915	-10.0745
HLA-A24:02	5HGA	9176	SVYLVQKVPGEANP	-6.56204	-6.67544
HLA-A24:02	5HGA	9176	SVYLVQKVPGEANP	-5.42271	-6.45801
HLA-B44:05	3DX8	9176	SVYLVQKVPGEANP	-7.85648	-8.89178
HLA-B44:05	3DX8	9176	SVYLVQKVPGEANP	-5.3978	-5.5112
HLA-A02:01	6TDR	9176	SVYLVQKVPGEANP	-3.37154	-4.40684

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Vaccine Design for the FusionNeoAntigens of DIS3L2-INPP5D

mRNA and peptide sequences of FusionNeoAntigens that have potential interaction with HLA-Is.

Fusion gene	Hchr	Hbp	Tchr	Tbp	Start in +/-13AA	End in +/-13AA	FusionNeoAntigen peptide sequence	FusionNeoAntigen RNA sequence
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	10	19	VQKQVPGEA	GTTCAAAAGCAGGTTCCTGGTGAGGCC
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	12	21	KVPGEANPI	AAGGTTCCTGGTGAGGCCAATCCCATC
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	12	22	KQVPGEANPI	AAGCAGGTTCCTGGTGAGGCCAATCCCATC
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	5	14	TSVYLVQKV	ACAAGCGTCTACTTGGTTCAAAAGGTT
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	6	14	SVYLVQKV	AGCGTCTACTTGGTTCAAAAGGTT
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	6	15	SVYLVQKQV	AGCGTCTACTTGGTTCAAAAGCAGGTT
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	8	18	YLVQKVPGEA	TACTTGGTTCAAAAGGTTCCTGGTGAGGCC

mRNA and peptide sequences of FusionNeoAntigens that have potential interaction with HLA-IIs.

Fusion gene	Hchr	Hbp	Tchr	Tbp	Start in +/-13AA	End in +/-13AA	FusionNeoAntigen peptide	FusionNEoAntigen RNA sequence
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	2	17	ERATSVYLVQKVPGE	GAGAGGGCTACAAGCGTCTACTTGGTTCAAAAGGTTCCTGGTGAG
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	3	18	RATSVYLVQKVPGEA	AGGGCTACAAGCGTCTACTTGGTTCAAAAGGTTCCTGGTGAGGCC
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	4	19	ATSVYLVQKQVPGEA	GCTACAAGCGTCTACTTGGTTCAAAAGCAGGTTCCTGGTGAGGCC
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	4	19	ATSVYLVQKVPGEAN	GCTACAAGCGTCTACTTGGTTCAAAAGGTTCCTGGTGAGGCCAAT
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	5	20	TSVYLVQKQVPGEAN	ACAAGCGTCTACTTGGTTCAAAAGCAGGTTCCTGGTGAGGCCAAT
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	5	20	TSVYLVQKVPGEANP	ACAAGCGTCTACTTGGTTCAAAAGGTTCCTGGTGAGGCCAATCCC
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	6	21	SVYLVQKQVPGEANP	AGCGTCTACTTGGTTCAAAAGCAGGTTCCTGGTGAGGCCAATCCC
DIS3L2-INPP5D	chr2	233103355	chr2	234054804	6	21	SVYLVQKVPGEANPI	AGCGTCTACTTGGTTCAAAAGGTTCCTGGTGAGGCCAATCCCATC

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Information of the samples that have these potential fusion neoantigens of DIS3L2-INPP5D

These samples were reported as having these fusion breakpoints. For individual breakpoints, we checked the open reading frames considering multiple gene isoforms and chose the in-frame fusion genes only. Then, we made fusion protein sequences and predicted the fusion neoantigens. These fusion-positive samples may have these potential fusion neoantigens.

Cancer type	Fusion gene	Hchr	Hbp	Henst	Tchr	Tbp	Tenst	Sample
ESCA	DIS3L2-INPP5D	chr2	233103355	ENST00000273009	chr2	234054804	ENST00000359570	TCGA-L5-A4OP
ESCA	DIS3L2-INPP5D	chr2	233103355	ENST00000273009	chr2	234054804	ENST00000455936	TCGA-L5-A4OP

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Potential target of CAR-T therapy development for DIS3L2-INPP5D

Predicted 3D structure. We used RoseTTAFold.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, to provide the retention of the transmembrane domain, we only show the protein feature retention information of those transmembrane features

* Minus value of BPloci means that the break point is located before the CDS.

- In-frame and retained 'Transmembrane'.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Subcellular localization prediction of the transmembrane domain retained fusion proteins
* We used DeepLoc 1.0. The order of the X-axis of the barplot is as follows: Entry_ID, Localization, Type, Nucleus, Cytoplasm, Extracellular, Mitochondrion, Cell_membrane, Endoplasmic_reticulum, Plastid, Golgi.apparatus, Lysosome.Vacuole, Peroxisome. Y-axis is the output score of DeepLoc. Clicking the image will open a new tab with a large image.

Hgene

Hchr

Hbp

Henst

Tgene

Tchr

Tbp

Tenst

DeepLoc result

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Related Drugs to DIS3L2-INPP5D

Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)

Hgene

Tgene

Drug

Source

PMID

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Related Diseases to DIS3L2-INPP5D

Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)

Hgene

Tgene

Disease

Source

PMID

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source

	Fusion Gene and Fusion Protein Summary
	Fusion Amino Acid Sequences (multiple BPs and multiple gene isoforms)
	Fusion Protein Breakpoint Sequences - (for the Screening of the FusionNeoAntigens)
	Potential FusionNeoAntigens in HLA I - (netMHCpan v4.1 + deepHLApan v1.1)
	Potential FusionNeoAntigens in HLA II - (netMHCIIpan v4.1)
	Fusion Breakpoint 14 AA Peptide Structure - (RoseTTAFold)
	Filtering FusionNeoAntigens Through Checking the Interaction with HLAs in 3D - (Glide)
	Vaccine Design for the FusionNeoAntigens (RNA/protein sequences)
	Potential target of CAR-T therapy development
	Information on the samples that have these potential fusion neoantigens
	Fusion Protein Targeting Drugs - (Manual Curation)
	Fusion Protein Related diseases - (Manual Curation)