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Center for Computational Systems Medicine
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Fusion Gene and Fusion Protein Summary

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Fusion Amino Acid Sequences (multiple BPs and multiple gene isoforms)

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Fusion Protein Breakpoint Sequences - (for the Screening of the FusionNeoAntigens)

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Potential FusionNeoAntigens in HLA I - (netMHCpan v4.1 + deepHLApan v1.1)

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Potential FusionNeoAntigens in HLA II - (netMHCIIpan v4.1)

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Fusion Breakpoint 14 AA Peptide Structure - (RoseTTAFold)

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Filtering FusionNeoAntigens Through Checking the Interaction with HLAs in 3D - (Glide)

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Vaccine Design for the FusionNeoAntigens (RNA/protein sequences)

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Potential target of CAR-T therapy development

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Information on the samples that have these potential fusion neoantigens

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Fusion Protein Targeting Drugs - (Manual Curation)

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Fusion Protein Related diseases - (Manual Curation)

Fusion Protein:GOSR2-CTNND1

Fusion Gene and Fusion Protein Summary

check button Fusion gene summary
Fusion partner gene informationFusion gene name: GOSR2-CTNND1
FusionPDB ID: 34037
FusionGDB2.0 ID: 34037
HgeneTgene
Gene symbol

GOSR2

CTNND1

Gene ID

9570

100528016

Gene namegolgi SNAP receptor complex member 2TMX2-CTNND1 readthrough (NMD candidate)
SynonymsBos1|EPM6|GS27CAS|CTNND1|p120(cas)|p120(ctn)
Cytomap

17q21.32

11q12.1

Type of geneprotein-codingncRNA
DescriptionGolgi SNAP receptor complex member 227 kDa Golgi SNARE proteinmembrinCadherin-associated Src substrateCatenin delta-1TMX2-CTNND1 readthrough (non-protein coding)p120 catenin
Modification date2020031320200313
UniProtAcc

O14653

Main function of 5'-partner protein: FUNCTION: Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network. {ECO:0000269|PubMed:9349823}.

O60716

Main function of 5'-partner protein: FUNCTION: Key regulator of cell-cell adhesion that associates with and regulates the cell adhesion properties of both C-, E- and N-cadherins, being critical for their surface stability (PubMed:14610055, PubMed:20371349). Beside cell-cell adhesion, regulates gene transcription through several transcription factors including ZBTB33/Kaiso2 and GLIS2, and the activity of Rho family GTPases and downstream cytoskeletal dynamics (PubMed:10207085, PubMed:20371349). Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors (PubMed:17344476). {ECO:0000269|PubMed:10207085, ECO:0000269|PubMed:14610055, ECO:0000269|PubMed:17344476, ECO:0000269|PubMed:20371349}.
Ensembl transtripts involved in fusion geneENST idsENST00000225567, ENST00000393456, 
ENST00000415811, ENST00000439730, 
ENST00000575949, ENST00000576910, 
ENST00000358694, ENST00000399050, 
ENST00000415361, ENST00000426142, 
ENST00000525902, ENST00000526357, 
ENST00000526772, ENST00000526938, 
ENST00000527467, ENST00000528232, 
ENST00000528621, ENST00000529526, 
ENST00000529873, ENST00000529986, 
ENST00000530748, ENST00000531014, 
ENST00000532245, ENST00000532463, 
ENST00000532649, ENST00000532787, 
ENST00000532844, ENST00000533667, 
ENST00000534579, ENST00000360682, 
ENST00000361332, ENST00000361391, 
ENST00000361796, ENST00000399039, 
ENST00000428599, ENST00000524630, 
ENST00000529919, ENST00000530094, 
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)* DoF score4 X 3 X 3=3617 X 21 X 10=3570
# samples 425
** MAII scorelog2(4/36*10)=0.15200309344505
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
log2(25/3570*10)=-3.83592407425437
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Fusion gene context

PubMed: GOSR2 [Title/Abstract] AND CTNND1 [Title/Abstract] AND fusion [Title/Abstract]

Fusion neoantigen context

PubMed: GOSR2 [Title/Abstract] AND CTNND1 [Title/Abstract] AND neoantigen [Title/Abstract]

Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)GOSR2(45000587)-CTNND1(57569205), # samples:1
Anticipated loss of major functional domain due to fusion event.GOSR2-CTNND1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
GOSR2-CTNND1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
GOSR2-CTNND1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
GOSR2-CTNND1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneGOSR2

GO:0006888

ER to Golgi vesicle-mediated transport

9349823

HgeneGOSR2

GO:0006891

intra-Golgi vesicle-mediated transport

9349823



check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr17:45000587/chr11:57569205)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonRetention analysis results of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features, are available here.

check buttonFusion gene breakpoints across GOSR2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across CTNND1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure


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Fusion Amino Acid Sequences


check buttonFusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)
BP loci
(transcript)
Predicted start
(transcript)
Predicted stop
(transcript)
Seq length
(amino acids)
ENST00000439730GOSR2chr1745000587+ENST00000524630CTNND1chr1157569205+517389601934624
ENST00000439730GOSR2chr1745000587+ENST00000529919CTNND1chr1157569205+358289601949629
ENST00000439730GOSR2chr1745000587+ENST00000399039CTNND1chr1157569205+399089601949629
ENST00000439730GOSR2chr1745000587+ENST00000360682CTNND1chr1157569205+484889601976638
ENST00000439730GOSR2chr1745000587+ENST00000361796CTNND1chr1157569205+480689601934624
ENST00000439730GOSR2chr1745000587+ENST00000361391CTNND1chr1157569205+482989601958632
ENST00000439730GOSR2chr1745000587+ENST00000530094CTNND1chr1157569205+489289602021653
ENST00000439730GOSR2chr1745000587+ENST00000428599CTNND1chr1157569205+480589601934624
ENST00000439730GOSR2chr1745000587+ENST00000361332CTNND1chr1157569205+489289602021653
ENST00000576910GOSR2chr1745000587+ENST00000524630CTNND1chr1157569205+5189105761950624
ENST00000576910GOSR2chr1745000587+ENST00000529919CTNND1chr1157569205+3598105761965629
ENST00000576910GOSR2chr1745000587+ENST00000399039CTNND1chr1157569205+4006105761965629
ENST00000576910GOSR2chr1745000587+ENST00000360682CTNND1chr1157569205+4864105761992638
ENST00000576910GOSR2chr1745000587+ENST00000361796CTNND1chr1157569205+4822105761950624
ENST00000576910GOSR2chr1745000587+ENST00000361391CTNND1chr1157569205+4845105761974632
ENST00000576910GOSR2chr1745000587+ENST00000530094CTNND1chr1157569205+4908105762037653
ENST00000576910GOSR2chr1745000587+ENST00000428599CTNND1chr1157569205+4821105761950624
ENST00000576910GOSR2chr1745000587+ENST00000361332CTNND1chr1157569205+4908105762037653
ENST00000393456GOSR2chr1745000587+ENST00000524630CTNND1chr1157569205+517086571931624
ENST00000393456GOSR2chr1745000587+ENST00000529919CTNND1chr1157569205+357986571946629
ENST00000393456GOSR2chr1745000587+ENST00000399039CTNND1chr1157569205+398786571946629
ENST00000393456GOSR2chr1745000587+ENST00000360682CTNND1chr1157569205+484586571973638
ENST00000393456GOSR2chr1745000587+ENST00000361796CTNND1chr1157569205+480386571931624
ENST00000393456GOSR2chr1745000587+ENST00000361391CTNND1chr1157569205+482686571955632
ENST00000393456GOSR2chr1745000587+ENST00000530094CTNND1chr1157569205+488986572018653
ENST00000393456GOSR2chr1745000587+ENST00000428599CTNND1chr1157569205+480286571931624
ENST00000393456GOSR2chr1745000587+ENST00000361332CTNND1chr1157569205+488986572018653
ENST00000415811GOSR2chr1745000587+ENST00000524630CTNND1chr1157569205+516884551929624
ENST00000415811GOSR2chr1745000587+ENST00000529919CTNND1chr1157569205+357784551944629
ENST00000415811GOSR2chr1745000587+ENST00000399039CTNND1chr1157569205+398584551944629
ENST00000415811GOSR2chr1745000587+ENST00000360682CTNND1chr1157569205+484384551971638
ENST00000415811GOSR2chr1745000587+ENST00000361796CTNND1chr1157569205+480184551929624
ENST00000415811GOSR2chr1745000587+ENST00000361391CTNND1chr1157569205+482484551953632
ENST00000415811GOSR2chr1745000587+ENST00000530094CTNND1chr1157569205+488784552016653
ENST00000415811GOSR2chr1745000587+ENST00000428599CTNND1chr1157569205+480084551929624
ENST00000415811GOSR2chr1745000587+ENST00000361332CTNND1chr1157569205+488784552016653
ENST00000575949GOSR2chr1745000587+ENST00000524630CTNND1chr1157569205+515369401914624
ENST00000575949GOSR2chr1745000587+ENST00000529919CTNND1chr1157569205+356269401929629
ENST00000575949GOSR2chr1745000587+ENST00000399039CTNND1chr1157569205+397069401929629
ENST00000575949GOSR2chr1745000587+ENST00000360682CTNND1chr1157569205+482869401956638
ENST00000575949GOSR2chr1745000587+ENST00000361796CTNND1chr1157569205+478669401914624
ENST00000575949GOSR2chr1745000587+ENST00000361391CTNND1chr1157569205+480969401938632
ENST00000575949GOSR2chr1745000587+ENST00000530094CTNND1chr1157569205+487269402001653
ENST00000575949GOSR2chr1745000587+ENST00000428599CTNND1chr1157569205+478569401914624
ENST00000575949GOSR2chr1745000587+ENST00000361332CTNND1chr1157569205+487269402001653
ENST00000225567GOSR2chr1745000587+ENST00000524630CTNND1chr1157569205+514460311905624
ENST00000225567GOSR2chr1745000587+ENST00000529919CTNND1chr1157569205+355360311920629
ENST00000225567GOSR2chr1745000587+ENST00000399039CTNND1chr1157569205+396160311920629
ENST00000225567GOSR2chr1745000587+ENST00000360682CTNND1chr1157569205+481960311947638
ENST00000225567GOSR2chr1745000587+ENST00000361796CTNND1chr1157569205+477760311905624
ENST00000225567GOSR2chr1745000587+ENST00000361391CTNND1chr1157569205+480060311929632
ENST00000225567GOSR2chr1745000587+ENST00000530094CTNND1chr1157569205+486360311992653
ENST00000225567GOSR2chr1745000587+ENST00000428599CTNND1chr1157569205+477660311905624
ENST00000225567GOSR2chr1745000587+ENST00000361332CTNND1chr1157569205+486360311992653

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000439730ENST00000524630GOSR2chr1745000587+CTNND1chr1157569205+0.0017698440.99823016
ENST00000439730ENST00000529919GOSR2chr1745000587+CTNND1chr1157569205+0.0050339450.9949661
ENST00000439730ENST00000399039GOSR2chr1745000587+CTNND1chr1157569205+0.0030087580.9969913
ENST00000439730ENST00000360682GOSR2chr1745000587+CTNND1chr1157569205+0.0017974960.99820244
ENST00000439730ENST00000361796GOSR2chr1745000587+CTNND1chr1157569205+0.0019487440.9980513
ENST00000439730ENST00000361391GOSR2chr1745000587+CTNND1chr1157569205+0.0017294690.9982705
ENST00000439730ENST00000530094GOSR2chr1745000587+CTNND1chr1157569205+0.0019285810.9980715
ENST00000439730ENST00000428599GOSR2chr1745000587+CTNND1chr1157569205+0.0019415680.9980584
ENST00000439730ENST00000361332GOSR2chr1745000587+CTNND1chr1157569205+0.0019285810.9980715
ENST00000576910ENST00000524630GOSR2chr1745000587+CTNND1chr1157569205+0.0017436710.99825627
ENST00000576910ENST00000529919GOSR2chr1745000587+CTNND1chr1157569205+0.0049663320.9950336
ENST00000576910ENST00000399039GOSR2chr1745000587+CTNND1chr1157569205+0.0030103310.9969896
ENST00000576910ENST00000360682GOSR2chr1745000587+CTNND1chr1157569205+0.0017899170.9982101
ENST00000576910ENST00000361796GOSR2chr1745000587+CTNND1chr1157569205+0.0019312110.99806875
ENST00000576910ENST00000361391GOSR2chr1745000587+CTNND1chr1157569205+0.0017215470.9982785
ENST00000576910ENST00000530094GOSR2chr1745000587+CTNND1chr1157569205+0.0019191810.99808085
ENST00000576910ENST00000428599GOSR2chr1745000587+CTNND1chr1157569205+0.0019242160.9980757
ENST00000576910ENST00000361332GOSR2chr1745000587+CTNND1chr1157569205+0.0019191810.99808085
ENST00000393456ENST00000524630GOSR2chr1745000587+CTNND1chr1157569205+0.0017787880.9982212
ENST00000393456ENST00000529919GOSR2chr1745000587+CTNND1chr1157569205+0.0050703170.9949297
ENST00000393456ENST00000399039GOSR2chr1745000587+CTNND1chr1157569205+0.0030436810.99695635
ENST00000393456ENST00000360682GOSR2chr1745000587+CTNND1chr1157569205+0.0018081790.9981918
ENST00000393456ENST00000361796GOSR2chr1745000587+CTNND1chr1157569205+0.0019585230.9980414
ENST00000393456ENST00000361391GOSR2chr1745000587+CTNND1chr1157569205+0.001740140.99825984
ENST00000393456ENST00000530094GOSR2chr1745000587+CTNND1chr1157569205+0.0019391910.99806076
ENST00000393456ENST00000428599GOSR2chr1745000587+CTNND1chr1157569205+0.0019513810.99804866
ENST00000393456ENST00000361332GOSR2chr1745000587+CTNND1chr1157569205+0.0019391910.99806076
ENST00000415811ENST00000524630GOSR2chr1745000587+CTNND1chr1157569205+0.0017922450.9982078
ENST00000415811ENST00000529919GOSR2chr1745000587+CTNND1chr1157569205+0.0051097670.9948902
ENST00000415811ENST00000399039GOSR2chr1745000587+CTNND1chr1157569205+0.0030788890.9969212
ENST00000415811ENST00000360682GOSR2chr1745000587+CTNND1chr1157569205+0.0018238720.9981761
ENST00000415811ENST00000361796GOSR2chr1745000587+CTNND1chr1157569205+0.0019743650.99802566
ENST00000415811ENST00000361391GOSR2chr1745000587+CTNND1chr1157569205+0.0017557680.9982443
ENST00000415811ENST00000530094GOSR2chr1745000587+CTNND1chr1157569205+0.0019553390.9980446
ENST00000415811ENST00000428599GOSR2chr1745000587+CTNND1chr1157569205+0.0019671640.99803287
ENST00000415811ENST00000361332GOSR2chr1745000587+CTNND1chr1157569205+0.0019553390.9980446
ENST00000575949ENST00000524630GOSR2chr1745000587+CTNND1chr1157569205+0.0018411620.9981589
ENST00000575949ENST00000529919GOSR2chr1745000587+CTNND1chr1157569205+0.0053051050.9946949
ENST00000575949ENST00000399039GOSR2chr1745000587+CTNND1chr1157569205+0.0031953460.9968047
ENST00000575949ENST00000360682GOSR2chr1745000587+CTNND1chr1157569205+0.0018757440.9981243
ENST00000575949ENST00000361796GOSR2chr1745000587+CTNND1chr1157569205+0.0020318250.99796814
ENST00000575949ENST00000361391GOSR2chr1745000587+CTNND1chr1157569205+0.0018060530.9981939
ENST00000575949ENST00000530094GOSR2chr1745000587+CTNND1chr1157569205+0.0020099320.99799013
ENST00000575949ENST00000428599GOSR2chr1745000587+CTNND1chr1157569205+0.0020251980.9979748
ENST00000575949ENST00000361332GOSR2chr1745000587+CTNND1chr1157569205+0.0020099320.99799013
ENST00000225567ENST00000524630GOSR2chr1745000587+CTNND1chr1157569205+0.0018347440.9981653
ENST00000225567ENST00000529919GOSR2chr1745000587+CTNND1chr1157569205+0.0052467510.99475324
ENST00000225567ENST00000399039GOSR2chr1745000587+CTNND1chr1157569205+0.0031751630.99682486
ENST00000225567ENST00000360682GOSR2chr1745000587+CTNND1chr1157569205+0.0018649760.998135
ENST00000225567ENST00000361796GOSR2chr1745000587+CTNND1chr1157569205+0.0020268960.99797314
ENST00000225567ENST00000361391GOSR2chr1745000587+CTNND1chr1157569205+0.0017943040.99820566
ENST00000225567ENST00000530094GOSR2chr1745000587+CTNND1chr1157569205+0.0019965380.9980034
ENST00000225567ENST00000428599GOSR2chr1745000587+CTNND1chr1157569205+0.0020197020.9979803
ENST00000225567ENST00000361332GOSR2chr1745000587+CTNND1chr1157569205+0.0019965380.9980034

check button Predicted full-length fusion amino acid sequences. For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among all the predicted ones.

Get the fusion protein sequences from here.

Fusion protein sequence information is available in the fasta format.
>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

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Fusion Protein Breakpoint Sequences for GOSR2-CTNND1

check button +/-13 AA sequence from the breakpoints of the fusion protein sequences.
HgeneHchrHbpTgeneTchrTbpLength(fusion protein)BP in fusion proteinPeptide

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Potential FusionNeoAntigen Information of GOSR2-CTNND1 in HLA I

check button Multiple sequence alignments of the potential FusionNeoAntigens per fusion breakpoints. If the MSA is empty, then it means that there were predicted fusion neoantigens in this fusion breakpoint, but those predicted fusion neoantigens were not across the breakpoint, which is not fusion-specific.

check button Potential FusionNeoAntigen Information
* We used NetMHCpan v4.1 (%rank<0.5) and deepHLApan v1.1 (immunogenic score>0.5)
Fusion geneHchrHbpTgeneTchrTbpHLA IFusionNeoAntigen peptideBinding scoreImmunogenic scoreNeoantigen start (at BP 13)Neoantigen end (at BP 13)

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Potential FusionNeoAntigen Information of GOSR2-CTNND1 in HLA II

check button Multiple sequence alignments of the potential FusionNeoAntigens per fusion breakpoints. If the MSA is empty, then it means that there were predicted fusion neoantigens in this fusion breakpoint, but those predicted fusion neoantigens were not across the breakpoint, which is not fusion-specific.

check button Potential FusionNeoAntigen Information
* We used NetMHCIIpan v4.1 (%rank<0.5).
Fusion geneHchrHbpTgeneTchrTbpHLA IIFusionNeoAntigen peptideNeoantigen start (at BP 13)Neoantigen end (at BP 13)

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Fusion breakpoint peptide structures of GOSR2-CTNND1

check button3D structures of the fusion breakpoint peptide of 14AA sequence that have potential fusion neoantigens
* The minimum length of the amino acid sequence in RoseTTAFold is 14AA. Here, we predicted the 14AA fusion protein breakpoint sequence not the fusion neoantigen peptide, which is shorter than 14 AA.

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Filtering FusionNeoAntigens Through Checking the Interaction with HLAs in 3D of GOSR2-CTNND1

check buttonVirtual screening between 25 HLAs (from PDB) and FusionNeoAntigens
* We used Glide to predict the interaction between HLAs and neoantigens.
HLA allelePDB IDFile nameBPseqDocking scoreGlide score

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Vaccine Design for the FusionNeoAntigens of GOSR2-CTNND1

check button mRNA and peptide sequences of FusionNeoAntigens that have potential interaction with HLA-Is.
Fusion geneHchrHbpTchrTbpStart in +/-13AAEnd in +/-13AAFusionNeoAntigen peptide sequenceFusionNeoAntigen RNA sequence

check button mRNA and peptide sequences of FusionNeoAntigens that have potential interaction with HLA-IIs.
Fusion geneHchrHbpTchrTbpStart in +/-13AAEnd in +/-13AAFusionNeoAntigen peptideFusionNEoAntigen RNA sequence

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Information of the samples that have these potential fusion neoantigens of GOSR2-CTNND1

check button These samples were reported as having these fusion breakpoints. For individual breakpoints, we checked the open reading frames considering multiple gene isoforms and chose the in-frame fusion genes only. Then, we made fusion protein sequences and predicted the fusion neoantigens. These fusion-positive samples may have these potential fusion neoantigens.
Cancer typeFusion geneHchrHbpHenstTchrTbpTenstSample

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Potential target of CAR-T therapy development for GOSR2-CTNND1

check button Predicted 3D structure. We used RoseTTAFold.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, to provide the retention of the transmembrane domain, we only show the protein feature retention information of those transmembrane features


* Minus value of BPloci means that the break point is located before the CDS.
- In-frame and retained 'Transmembrane'.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

check button Subcellular localization prediction of the transmembrane domain retained fusion proteins
* We used DeepLoc 1.0. The order of the X-axis of the barplot is as follows: Entry_ID, Localization, Type, Nucleus, Cytoplasm, Extracellular, Mitochondrion, Cell_membrane, Endoplasmic_reticulum, Plastid, Golgi.apparatus, Lysosome.Vacuole, Peroxisome. Y-axis is the output score of DeepLoc. Clicking the image will open a new tab with a large image.
HgeneHchrHbpHenstTgeneTchrTbpTenstDeepLoc result

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Related Drugs to GOSR2-CTNND1

check button Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDrugSourcePMID

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Related Diseases to GOSR2-CTNND1

check button Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDiseaseSourcePMID

check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource