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Center for Computational Systems Medicine
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Fusion Gene and Fusion Protein Summary

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Fusion Amino Acid Sequences (multiple BPs and multiple gene isoforms)

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Fusion Protein Breakpoint Sequences - (for the Screening of the FusionNeoAntigens)

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Potential FusionNeoAntigens in HLA I - (netMHCpan v4.1 + deepHLApan v1.1)

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Potential FusionNeoAntigens in HLA II - (netMHCIIpan v4.1)

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Fusion Breakpoint 14 AA Peptide Structure - (RoseTTAFold)

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Filtering FusionNeoAntigens Through Checking the Interaction with HLAs in 3D - (Glide)

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Vaccine Design for the FusionNeoAntigens (RNA/protein sequences)

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Potential target of CAR-T therapy development

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Information on the samples that have these potential fusion neoantigens

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Fusion Protein Targeting Drugs - (Manual Curation)

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Fusion Protein Related diseases - (Manual Curation)

Fusion Protein:MPHOSPH8-FLNA

Fusion Gene and Fusion Protein Summary

check button Fusion gene summary
Fusion partner gene informationFusion gene name: MPHOSPH8-FLNA
FusionPDB ID: 54693
FusionGDB2.0 ID: 54693
HgeneTgene
Gene symbol

MPHOSPH8

FLNA

Gene ID

54737

2316

Gene nameM-phase phosphoprotein 8filamin A
SynonymsHSMPP8|TWA3|mpp8ABP-280|ABPX|CSBS|CVD1|FGS2|FLN|FLN-A|FLN1|FMD|MNS|NHBP|OPD|OPD1|OPD2|XLVD|XMVD
Cytomap

13q12.11

Xq28

Type of geneprotein-codingprotein-coding
DescriptionM-phase phosphoprotein 8M-phase phosphoprotein, mppM-phase phosphoprotein, mpp8two hybrid-associated protein 3 with RanBPMfilamin-Aactin binding protein 280alpha-filaminendothelial actin-binding proteinepididymis secretory sperm binding proteinfilamin A, alphafilamin-1non-muscle filamin
Modification date2020031320200313
UniProtAcc

Q99549

Main function of 5'-partner protein: FUNCTION: Heterochromatin component that specifically recognizes and binds methylated 'Lys-9' of histone H3 (H3K9me) and promotes recruitment of proteins that mediate epigenetic repression (PubMed:20871592, PubMed:26022416). Mediates recruitment of the HUSH complex to H3K9me3 sites: the HUSH complex is recruited to genomic loci rich in H3K9me3 and is required to maintain transcriptional silencing by promoting recruitment of SETDB1, a histone methyltransferase that mediates further deposition of H3K9me3, as well as MORC2 (PubMed:26022416, PubMed:28581500). Binds H3K9me and promotes DNA methylation by recruiting DNMT3A to target CpG sites; these can be situated within the coding region of the gene (PubMed:20871592). Mediates down-regulation of CDH1 expression (PubMed:20871592). Also represses L1 retrotransposons in collaboration with MORC2 and, probably, SETDB1, the silencing is dependent of repressive epigenetic modifications, such as H3K9me3 mark. Silencing events often occur within introns of transcriptionally active genes, and lead to the down-regulation of host gene expression (PubMed:29211708). The HUSH complex is also involved in the silencing of unintegrated retroviral DNA by being recruited by ZNF638: some part of the retroviral DNA formed immediately after infection remains unintegrated in the host genome and is transcriptionally repressed (PubMed:30487602). {ECO:0000269|PubMed:20871592, ECO:0000269|PubMed:26022416, ECO:0000269|PubMed:28581500, ECO:0000269|PubMed:29211708, ECO:0000269|PubMed:30487602}.

P21333

Main function of 5'-partner protein: FUNCTION: Promotes orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. Anchors various transmembrane proteins to the actin cytoskeleton and serves as a scaffold for a wide range of cytoplasmic signaling proteins. Interaction with FLNB may allow neuroblast migration from the ventricular zone into the cortical plate. Tethers cell surface-localized furin, modulates its rate of internalization and directs its intracellular trafficking (By similarity). Involved in ciliogenesis. Plays a role in cell-cell contacts and adherens junctions during the development of blood vessels, heart and brain organs. Plays a role in platelets morphology through interaction with SYK that regulates ITAM- and ITAM-like-containing receptor signaling, resulting in by platelet cytoskeleton organization maintenance (By similarity). During the axon guidance process, required for growth cone collapse induced by SEMA3A-mediated stimulation of neurons (PubMed:25358863). {ECO:0000250, ECO:0000250|UniProtKB:Q8BTM8, ECO:0000269|PubMed:22121117, ECO:0000269|PubMed:25358863}.
Ensembl transtripts involved in fusion geneENST idsENST00000361479, ENST00000414242, 
ENST00000496525, 
ENST00000344736, 
ENST00000369856, ENST00000498491, 
ENST00000360319, ENST00000369850, 
ENST00000422373, 
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)* DoF score8 X 11 X 5=44025 X 31 X 6=4650
# samples 1231
** MAII scorelog2(12/440*10)=-1.87446911791614
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(31/4650*10)=-3.90689059560852
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Fusion gene context

PubMed: MPHOSPH8 [Title/Abstract] AND FLNA [Title/Abstract] AND fusion [Title/Abstract]

Fusion neoantigen context

PubMed: MPHOSPH8 [Title/Abstract] AND FLNA [Title/Abstract] AND neoantigen [Title/Abstract]

Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)MPHOSPH8(20224400)-FLNA(153596458), # samples:1
Anticipated loss of major functional domain due to fusion event.MPHOSPH8-FLNA seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
MPHOSPH8-FLNA seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
MPHOSPH8-FLNA seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
MPHOSPH8-FLNA seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneMPHOSPH8

GO:0045814

negative regulation of gene expression, epigenetic

26022416|28581500|29211708

HgeneMPHOSPH8

GO:0090309

positive regulation of methylation-dependent chromatin silencing

28581500|29211708

TgeneFLNA

GO:0016479

negative regulation of transcription by RNA polymerase I

22307607

TgeneFLNA

GO:0030334

regulation of cell migration

16291724

TgeneFLNA

GO:0031532

actin cytoskeleton reorganization

10051605

TgeneFLNA

GO:0034394

protein localization to cell surface

18322202

TgeneFLNA

GO:0043113

receptor clustering

10692483

TgeneFLNA

GO:0043433

negative regulation of DNA-binding transcription factor activity

15684392

TgeneFLNA

GO:0044319

wound healing, spreading of cells

16291724

TgeneFLNA

GO:0045184

establishment of protein localization

18322202

TgeneFLNA

GO:0051764

actin crosslink formation

10051605

TgeneFLNA

GO:0072659

protein localization to plasma membrane

24951510

TgeneFLNA

GO:0090307

mitotic spindle assembly

18548008

TgeneFLNA

GO:1901381

positive regulation of potassium ion transmembrane transport

24951510



check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr13:20224400/chrX:153596458)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonRetention analysis results of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features, are available here.

check buttonFusion gene breakpoints across MPHOSPH8 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across FLNA (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure


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Fusion Amino Acid Sequences


check buttonFusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)
BP loci
(transcript)
Predicted start
(transcript)
Predicted stop
(transcript)
Seq length
(amino acids)
ENST00000414242MPHOSPH8chr1320224400+ENST00000360319FLNAchrX153596458-9547167710192233040
ENST00000414242MPHOSPH8chr1320224400+ENST00000422373FLNAchrX153596458-9541167710192233040
ENST00000414242MPHOSPH8chr1320224400+ENST00000369850FLNAchrX153596458-9449167710192473048
ENST00000361479MPHOSPH8chr1320224400+ENST00000360319FLNAchrX153596458-951416446891903040
ENST00000361479MPHOSPH8chr1320224400+ENST00000422373FLNAchrX153596458-950816446891903040
ENST00000361479MPHOSPH8chr1320224400+ENST00000369850FLNAchrX153596458-941616446892143048

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000414242ENST00000360319MPHOSPH8chr1320224400+FLNAchrX153596458-0.0009008420.99909914
ENST00000414242ENST00000422373MPHOSPH8chr1320224400+FLNAchrX153596458-0.0008972650.9991027
ENST00000414242ENST00000369850MPHOSPH8chr1320224400+FLNAchrX153596458-0.0008978020.99910223
ENST00000361479ENST00000360319MPHOSPH8chr1320224400+FLNAchrX153596458-0.0008902630.9991097
ENST00000361479ENST00000422373MPHOSPH8chr1320224400+FLNAchrX153596458-0.0008870030.999113
ENST00000361479ENST00000369850MPHOSPH8chr1320224400+FLNAchrX153596458-0.0008878330.9991122

check button Predicted full-length fusion amino acid sequences. For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among all the predicted ones.

Get the fusion protein sequences from here.

Fusion protein sequence information is available in the fasta format.
>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

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Fusion Protein Breakpoint Sequences for MPHOSPH8-FLNA

check button +/-13 AA sequence from the breakpoints of the fusion protein sequences.
HgeneHchrHbpTgeneTchrTbpLength(fusion protein)BP in fusion proteinPeptide
MPHOSPH8chr1320224400FLNAchrX15359645816441780SGTTNKPNKFTVETRGAGTGGLGLAV
MPHOSPH8chr1320224400FLNAchrX1535964581644525EVLDSVCQADENSDSKAIVDGNLKLI
MPHOSPH8chr1320224400FLNAchrX15359645816771780SGTTNKPNKFTVETRGAGTGGLGLAV
MPHOSPH8chr1320224400FLNAchrX1535964581677525EVLDSVCQADENSDSKAIVDGNLKLI

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Potential FusionNeoAntigen Information of MPHOSPH8-FLNA in HLA I

check button Multiple sequence alignments of the potential FusionNeoAntigens per fusion breakpoints. If the MSA is empty, then it means that there were predicted fusion neoantigens in this fusion breakpoint, but those predicted fusion neoantigens were not across the breakpoint, which is not fusion-specific.
MPHOSPH8-FLNA_20224400_153596458.msa

check button Potential FusionNeoAntigen Information
* We used NetMHCpan v4.1 (%rank<0.5) and deepHLApan v1.1 (immunogenic score>0.5)
Fusion geneHchrHbpTgeneTchrTbpHLA IFusionNeoAntigen peptideBinding scoreImmunogenic scoreNeoantigen start (at BP 13)Neoantigen end (at BP 13)
MPHOSPH8-FLNAchr1320224400chrX1535964581644HLA-B67:01KPNKFTVET0.30190.7433514

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Potential FusionNeoAntigen Information of MPHOSPH8-FLNA in HLA II

check button Multiple sequence alignments of the potential FusionNeoAntigens per fusion breakpoints. If the MSA is empty, then it means that there were predicted fusion neoantigens in this fusion breakpoint, but those predicted fusion neoantigens were not across the breakpoint, which is not fusion-specific.
MPHOSPH8-FLNA_20224400_153596458.msa

check button Potential FusionNeoAntigen Information
* We used NetMHCIIpan v4.1 (%rank<0.5).
Fusion geneHchrHbpTgeneTchrTbpHLA IIFusionNeoAntigen peptideNeoantigen start (at BP 13)Neoantigen end (at BP 13)
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0466PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0466KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0466NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0466NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0801PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0801KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0801NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0802PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0802KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0802NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0802NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0803PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0803KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0805PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0805KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0805NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0807PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0807KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0808PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0808KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0808NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0809PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0809KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0809NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0809NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0811PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0811KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0811NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0813PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0813KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0813NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0813NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0814PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0814KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0815PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0815KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0815NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0815NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0816PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0816KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0816NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0818PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0818KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0820PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0820KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0821PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0821KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0821NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0821NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0823PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0823KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0824PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0824KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0824NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0824NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0826PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0826KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0826NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0827PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0827KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0829PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0829KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0830PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0830KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0830NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0830NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0831PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0831KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0833PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0833KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0835PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0835KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0836PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0836KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0837PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0837KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0838PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0838KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0839PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0839KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0839NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0840PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0840KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-0840NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1101PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1101KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1101NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1101NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1104PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1105PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1105KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1105NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1105NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1106PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1108PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1108KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1108NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1108NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1109PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1109KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1109NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1109NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1110PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1110KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1110NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1110NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1111PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1111KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1111NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1111NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1112PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1112KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1112NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1112NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1114PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1114KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1115PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1115KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1115NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1115NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1118PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1119PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1119KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1119NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1119NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1120PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1120KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1124PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1124KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1124NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1124NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1125PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1127PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1127KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1127NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1127NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1128PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1128KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1128NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1128NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1129PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1129KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1129NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1129NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1130PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1130KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1131PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1131KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1131NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1131NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1132PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1132KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1132NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1132NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1133PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1133KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1133NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1133NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1135PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1137PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1137KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1137NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1137NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1138PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1139PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1139KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1139NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1139NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1141PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1142PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1143PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1144PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1145PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1145KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1145NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1145NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1146PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1147PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1149PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1149KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1149NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1149NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1150PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1150KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1151PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1151KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1151NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1151NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1153PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1153KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1153NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1153NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1153TNKPNKFTVETRGAG318
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1154PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1154KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1156PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1156KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1158PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1159PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1160PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1161PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1161KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1161NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1161NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1162PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1162KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1162NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1162NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1164PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1164KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1164NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1164NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1166PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1166KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1166NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1166NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1168PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1168KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1168NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1169PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1169KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1169NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1169NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1172PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1172KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1172NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1172NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1173PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1173KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1173NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1173NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1173TNKPNKFTVETRGAG318
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1174PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1174KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1174NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1174NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1175PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1175KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1175NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1175NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1177PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1178PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1179PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1179KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1179NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1179NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1180PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1180KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1180NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1180NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1180TNKPNKFTVETRGAG318
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1181PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1181KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1181NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1181NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1182PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1182KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1182NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1182NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1183PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1183KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1183NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1183NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1184PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1184KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1186PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1186KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1187PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1187KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1187NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1187NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1187TNKPNKFTVETRGAG318
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1188PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1188KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1190PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1190KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1190NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1190NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1191PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1191KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1191NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1191NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1192PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1192KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1193PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1193KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1193NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1193NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1193TNKPNKFTVETRGAG318
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1194PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1194KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1194NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1194NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1195PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1195KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1195NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1195NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1196PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1196KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1196NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1196NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1302PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1302KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1303PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1303KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1303NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1305PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1305KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1305NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1305NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1306PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1307PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1307KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1307NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1307NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-13100PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-13100KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-13100NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-13100NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-13101PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-13101KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-13101NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1310PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1310KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1310NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1311PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1312PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1312KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1312NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1313PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1313KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1313NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1314PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1314KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1314NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1314NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1316PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1316KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1318PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1321PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1321KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1321NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1321NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1323PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1323KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1326PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1326KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1326NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1326NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1329PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1329KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1329NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1330PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1330KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1330NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1333PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1333KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1333NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1333NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1334PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1334KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1336PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1336KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1336NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1336NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1337PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1337KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1337NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1337NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1337TNKPNKFTVETRGAG318
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1338PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1338KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1339PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1339KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1341PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1341KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1341NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1342PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1346PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1346KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1346NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1346NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1347PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1347KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1347NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1347NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1349PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1349KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1349NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1349NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1350PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1350KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1350NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1350NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1355PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1355KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1355NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1355NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1356PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1356KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1356NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1356NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1360PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1360KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1360NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1360NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1360TNKPNKFTVETRGAG318
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1362PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1362KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1362NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1362NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1363PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1363KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1363NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1363NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1365PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1365KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1366PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1366KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1366NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1366NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1367PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1373PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1373KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1374PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1374KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1382PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1382KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1382NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1382NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1385PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1385KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1385NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1385NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1386PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1386KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1386NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1386NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1388PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1388KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1388NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1388NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1390PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1390KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1390NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1395PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1395KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1395NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1396PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1396KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1397PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1397KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1399PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1399KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1402PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1402KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1402NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1402NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1403PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1403KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1403NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1403NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1409PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1409KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1409NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1409NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1413PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1413KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1413NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1414PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1414KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1414NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1414NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1419PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1419KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1419NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1419NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1422PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1422KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1422NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1422NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1424PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1424KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1424NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1425PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1425KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1425NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1425NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1427PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1427KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1427NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1427NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1430PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1430KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1430NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1430NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1436PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1436KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1436NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1436NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1440PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1440KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1440NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1440NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1441PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1441KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1441NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1441NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1442PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1442KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1442NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1442NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1444PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1444KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1444NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1444NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1446PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1446KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1447PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1447KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1447NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1449PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1449KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1451PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1451KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1451NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1451NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1453PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1453KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1453NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1453NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1463PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1463KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1467PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1467KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1467NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1467NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1469PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1469KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1469NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1469NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1477PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1477KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1477NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1477NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1484PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1485PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1485KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1485NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1489PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1489KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1489NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1489NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1494PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1494KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1494NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1494NKFTVETRGAGTGGL722
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1498PNKFTVETRGAGTGG621
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1498KPNKFTVETRGAGTG520
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1498NKPNKFTVETRGAGT419
MPHOSPH8-FLNAchr1320224400chrX1535964581644DRB1-1498NKFTVETRGAGTGGL722

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Fusion breakpoint peptide structures of MPHOSPH8-FLNA

check button3D structures of the fusion breakpoint peptide of 14AA sequence that have potential fusion neoantigens
* The minimum length of the amino acid sequence in RoseTTAFold is 14AA. Here, we predicted the 14AA fusion protein breakpoint sequence not the fusion neoantigen peptide, which is shorter than 14 AA.
File nameBPseqHgeneTgeneHchrHbpTchrTbpAAlen
6827PNKFTVETRGAGTGMPHOSPH8FLNAchr1320224400chrX1535964581644

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Filtering FusionNeoAntigens Through Checking the Interaction with HLAs in 3D of MPHOSPH8-FLNA

check buttonVirtual screening between 25 HLAs (from PDB) and FusionNeoAntigens
* We used Glide to predict the interaction between HLAs and neoantigens.
HLA allelePDB IDFile nameBPseqDocking scoreGlide score
HLA-B14:023BVN6827PNKFTVETRGAGTG-7.9962-8.1096
HLA-B14:023BVN6827PNKFTVETRGAGTG-5.70842-6.74372
HLA-B52:013W396827PNKFTVETRGAGTG-6.83737-6.95077
HLA-B52:013W396827PNKFTVETRGAGTG-4.4836-5.5189
HLA-A11:014UQ26827PNKFTVETRGAGTG-10.0067-10.1201
HLA-A11:014UQ26827PNKFTVETRGAGTG-9.03915-10.0745
HLA-A24:025HGA6827PNKFTVETRGAGTG-6.56204-6.67544
HLA-A24:025HGA6827PNKFTVETRGAGTG-5.42271-6.45801
HLA-B44:053DX86827PNKFTVETRGAGTG-7.85648-8.89178
HLA-B44:053DX86827PNKFTVETRGAGTG-5.3978-5.5112
HLA-A02:016TDR6827PNKFTVETRGAGTG-3.37154-4.40684

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Vaccine Design for the FusionNeoAntigens of MPHOSPH8-FLNA

check button mRNA and peptide sequences of FusionNeoAntigens that have potential interaction with HLA-Is.
Fusion geneHchrHbpTchrTbpStart in +/-13AAEnd in +/-13AAFusionNeoAntigen peptide sequenceFusionNeoAntigen RNA sequence
MPHOSPH8-FLNAchr1320224400chrX153596458514KPNKFTVETTGTGCCAAGCAGATGAGAATTCAGACA

check button mRNA and peptide sequences of FusionNeoAntigens that have potential interaction with HLA-IIs.
Fusion geneHchrHbpTchrTbpStart in +/-13AAEnd in +/-13AAFusionNeoAntigen peptideFusionNEoAntigen RNA sequence
MPHOSPH8-FLNAchr1320224400chrX153596458318TNKPNKFTVETRGAGACAGCGTGTGCCAAGCAGATGAGAATTCAGACAGCAAGGCCATCG
MPHOSPH8-FLNAchr1320224400chrX153596458419NKPNKFTVETRGAGTGCGTGTGCCAAGCAGATGAGAATTCAGACAGCAAGGCCATCGTGG
MPHOSPH8-FLNAchr1320224400chrX153596458520KPNKFTVETRGAGTGTGTGCCAAGCAGATGAGAATTCAGACAGCAAGGCCATCGTGGACG
MPHOSPH8-FLNAchr1320224400chrX153596458621PNKFTVETRGAGTGGGCCAAGCAGATGAGAATTCAGACAGCAAGGCCATCGTGGACGGGA
MPHOSPH8-FLNAchr1320224400chrX153596458722NKFTVETRGAGTGGLAAGCAGATGAGAATTCAGACAGCAAGGCCATCGTGGACGGGAACC

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Information of the samples that have these potential fusion neoantigens of MPHOSPH8-FLNA

check button These samples were reported as having these fusion breakpoints. For individual breakpoints, we checked the open reading frames considering multiple gene isoforms and chose the in-frame fusion genes only. Then, we made fusion protein sequences and predicted the fusion neoantigens. These fusion-positive samples may have these potential fusion neoantigens.
Cancer typeFusion geneHchrHbpHenstTchrTbpTenstSample
Non-CancerMPHOSPH8-FLNAchr1320224400ENST00000361479chrX153596458ENST00000360319ERR315430

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Potential target of CAR-T therapy development for MPHOSPH8-FLNA

check button Predicted 3D structure. We used RoseTTAFold.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, to provide the retention of the transmembrane domain, we only show the protein feature retention information of those transmembrane features


* Minus value of BPloci means that the break point is located before the CDS.
- In-frame and retained 'Transmembrane'.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

check button Subcellular localization prediction of the transmembrane domain retained fusion proteins
* We used DeepLoc 1.0. The order of the X-axis of the barplot is as follows: Entry_ID, Localization, Type, Nucleus, Cytoplasm, Extracellular, Mitochondrion, Cell_membrane, Endoplasmic_reticulum, Plastid, Golgi.apparatus, Lysosome.Vacuole, Peroxisome. Y-axis is the output score of DeepLoc. Clicking the image will open a new tab with a large image.
HgeneHchrHbpHenstTgeneTchrTbpTenstDeepLoc result

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Related Drugs to MPHOSPH8-FLNA

check button Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDrugSourcePMID

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Related Diseases to MPHOSPH8-FLNA

check button Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDiseaseSourcePMID

check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource