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Fusion Protein:TAF2-ALDH16A1

Fusion Gene and Fusion Protein Summary

Fusion gene summary

Fusion partner gene information	Fusion gene name: TAF2-ALDH16A1
	FusionPDB ID: 88772
	FusionGDB2.0 ID: 88772
		Hgene	Tgene
	Gene symbol	TAF2	ALDH16A1
	Gene ID	6873	126133
	Gene name	TATA-box binding protein associated factor 2	aldehyde dehydrogenase 16 family member A1
	Synonyms	CIF150\|MRT40\|TAF2B\|TAFII150	-
	Cytomap	8q24.12	19q13.33
	Type of gene	protein-coding	protein-coding
	Description	transcription initiation factor TFIID subunit 2150 kDa cofactor of initiator functionRNA polymerase II TBP-associated factor subunit BTAF(II)150TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDaTATA box binding protein (	aldehyde dehydrogenase family 16 member A1
	Modification date	20200313	20200313
	UniProtAcc	.	Q8IZ83 Main function of 5'-partner protein:
Ensembl transtripts involved in fusion gene	ENST ids	ENST00000378164, ENST00000519355,	ENST00000598015, ENST00000293350, ENST00000433981, ENST00000455361, ENST00000540132,
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)	* DoF score	8 X 10 X 7=560	9 X 10 X 7=630
	# samples	14	13
	** MAII score	log2(14/560*10)=-2 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(13/630*10)=-2.27684020535882 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Fusion gene context	PubMed: TAF2 [Title/Abstract] AND ALDH16A1 [Title/Abstract] AND fusion [Title/Abstract]
Fusion neoantigen context	PubMed: TAF2 [Title/Abstract] AND ALDH16A1 [Title/Abstract] AND neoantigen [Title/Abstract]
Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)	TAF2(120843917)-ALDH16A1(49967111), # samples:3
Anticipated loss of major functional domain due to fusion event.	TAF2-ALDH16A1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. TAF2-ALDH16A1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Hgene	TAF2	GO:0006367	transcription initiation from RNA polymerase II promoter	9418870

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr8:120843917/chr19:49967111)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Retention analysis results of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features, are available here.

Fusion gene breakpoints across TAF2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across ALDH16A1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

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Fusion Amino Acid Sequences

Fusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000378164	TAF2	chr8	120843917	-	ENST00000293350	ALDH16A1	chr19	49967111	+	2329	437	137	1747	536
ENST00000378164	TAF2	chr8	120843917	-	ENST00000540132	ALDH16A1	chr19	49967111	+	1815	437	137	1747	536
ENST00000378164	TAF2	chr8	120843917	-	ENST00000455361	ALDH16A1	chr19	49967111	+	1866	437	137	1747	536
ENST00000378164	TAF2	chr8	120843917	-	ENST00000433981	ALDH16A1	chr19	49967111	+	1868	437	137	1747	536
ENST00000378164	TAF2	chr8	120843916	-	ENST00000293350	ALDH16A1	chr19	49967110	+	2329	437	137	1747	536
ENST00000378164	TAF2	chr8	120843916	-	ENST00000540132	ALDH16A1	chr19	49967110	+	1815	437	137	1747	536
ENST00000378164	TAF2	chr8	120843916	-	ENST00000455361	ALDH16A1	chr19	49967110	+	1866	437	137	1747	536
ENST00000378164	TAF2	chr8	120843916	-	ENST00000433981	ALDH16A1	chr19	49967110	+	1868	437	137	1747	536
ENST00000378164	TAF2	chr8	120843917	-	ENST00000293350	ALDH16A1	chr19	49967384	+	2233	437	137	1651	504
ENST00000378164	TAF2	chr8	120843917	-	ENST00000540132	ALDH16A1	chr19	49967384	+	1719	437	137	1651	504
ENST00000378164	TAF2	chr8	120843917	-	ENST00000455361	ALDH16A1	chr19	49967384	+	1770	437	137	1651	504
ENST00000378164	TAF2	chr8	120843917	-	ENST00000433981	ALDH16A1	chr19	49967384	+	1772	437	137	1651	504

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000378164	ENST00000293350	TAF2	chr8	120843917	-	ALDH16A1	chr19	49967111	+	0.106859244	0.89314073
ENST00000378164	ENST00000540132	TAF2	chr8	120843917	-	ALDH16A1	chr19	49967111	+	0.13860266	0.8613974
ENST00000378164	ENST00000455361	TAF2	chr8	120843917	-	ALDH16A1	chr19	49967111	+	0.13608404	0.863916
ENST00000378164	ENST00000433981	TAF2	chr8	120843917	-	ALDH16A1	chr19	49967111	+	0.13796711	0.86203295
ENST00000378164	ENST00000293350	TAF2	chr8	120843916	-	ALDH16A1	chr19	49967110	+	0.106859244	0.89314073
ENST00000378164	ENST00000540132	TAF2	chr8	120843916	-	ALDH16A1	chr19	49967110	+	0.13860266	0.8613974
ENST00000378164	ENST00000455361	TAF2	chr8	120843916	-	ALDH16A1	chr19	49967110	+	0.13608404	0.863916
ENST00000378164	ENST00000433981	TAF2	chr8	120843916	-	ALDH16A1	chr19	49967110	+	0.13796711	0.86203295
ENST00000378164	ENST00000293350	TAF2	chr8	120843917	-	ALDH16A1	chr19	49967384	+	0.1764111	0.8235889
ENST00000378164	ENST00000540132	TAF2	chr8	120843917	-	ALDH16A1	chr19	49967384	+	0.21969749	0.7803025
ENST00000378164	ENST00000455361	TAF2	chr8	120843917	-	ALDH16A1	chr19	49967384	+	0.22015098	0.779849
ENST00000378164	ENST00000433981	TAF2	chr8	120843917	-	ALDH16A1	chr19	49967384	+	0.22245476	0.7775453

Predicted full-length fusion amino acid sequences. For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among all the predicted ones.

Get the fusion protein sequences from here.

Fusion protein sequence information is available in the fasta format.
>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

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Fusion Protein Breakpoint Sequences for TAF2-ALDH16A1

+/-13 AA sequence from the breakpoints of the fusion protein sequences.

Hgene	Hchr	Hbp	Tgene	Tchr	Tbp	Length(fusion protein)	BP in fusion protein	Peptide
TAF2	chr8	120843916	ALDH16A1	chr19	49967110	437	100	CINNINFQRKSVVVFQAGDVPSERPF
TAF2	chr8	120843917	ALDH16A1	chr19	49967111	437	100	CINNINFQRKSVVVFQAGDVPSERPF
TAF2	chr8	120843917	ALDH16A1	chr19	49967384	437	100	CINNINFQRKSVVVPWPVVVASPFRT

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Potential FusionNeoAntigen Information of TAF2-ALDH16A1 in HLA I

Multiple sequence alignments of the potential FusionNeoAntigens per fusion breakpoints. If the MSA is empty, then it means that there were predicted fusion neoantigens in this fusion breakpoint, but those predicted fusion neoantigens were not across the breakpoint, which is not fusion-specific.

TAF2-ALDH16A1_120843916_49967110.msa
TAF2-ALDH16A1_120843917_49967384.msa

Potential FusionNeoAntigen Information
* We used NetMHCpan v4.1 (%rank<0.5) and deepHLApan v1.1 (immunogenic score>0.5)

Fusion gene	Hchr	Hbp	Tgene	Tchr	Tbp	HLA I	FusionNeoAntigen peptide	Binding score	Immunogenic score	Neoantigen start (at BP 13)	Neoantigen end (at BP 13)
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	HLA-B15:01	FQRKSVVVF	0.9997	0.7847	6	15
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	HLA-B15:25	FQRKSVVVF	0.974	0.8331	6	15
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	HLA-B15:02	FQRKSVVVF	0.9737	0.8463	6	15
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	HLA-B15:03	FQRKSVVVF	0.9286	0.5958	6	15
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	HLA-B15:18	FQRKSVVVF	0.8161	0.5807	6	15
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	HLA-B39:13	FQRKSVVVF	0.4294	0.5877	6	15
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	HLA-B13:01	FQRKSVVVF	0.2786	0.6006	6	15
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	HLA-B52:01	FQRKSVVVF	0.0946	0.5819	6	15
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	HLA-B15:01	NFQRKSVVVF	0.9358	0.7031	5	15
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	HLA-C07:05	QRKSVVVF	0.9995	0.9012	7	15
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	HLA-C07:46	QRKSVVVF	0.9994	0.7736	7	15
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	HLA-C12:16	QRKSVVVF	0.9886	0.9082	7	15
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	HLA-B15:07	FQRKSVVVF	0.9986	0.5151	6	15
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	HLA-B15:04	FQRKSVVVF	0.9957	0.7822	6	15
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	HLA-C12:12	FQRKSVVVF	0.9936	0.9086	6	15
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	HLA-C12:16	FQRKSVVVF	0.978	0.936	6	15
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	HLA-B15:21	FQRKSVVVF	0.9724	0.8159	6	15
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	HLA-C12:04	FQRKSVVVF	0.9087	0.979	6	15
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	HLA-C06:03	FQRKSVVVF	0.8997	0.9797	6	15
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	HLA-B15:31	FQRKSVVVF	0.8136	0.8135	6	15
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	HLA-C07:05	FQRKSVVVF	0.7677	0.8046	6	15
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	HLA-C07:29	FQRKSVVVF	0.7056	0.7929	6	15
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	HLA-B15:05	FQRKSVVVF	0.7024	0.802	6	15
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	HLA-C07:10	FQRKSVVVF	0.702	0.8956	6	15
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	HLA-C07:27	FQRKSVVVF	0.7007	0.8339	6	15
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	HLA-C07:67	FQRKSVVVF	0.6897	0.8534	6	15
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	HLA-C07:80	FQRKSVVVF	0.6897	0.8534	6	15
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	HLA-C03:14	FQRKSVVVF	0.6728	0.9609	6	15
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	HLA-C07:46	FQRKSVVVF	0.6645	0.6628	6	15
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	HLA-C02:06	FQRKSVVVF	0.4703	0.9218	6	15
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	HLA-B73:01	QRKSVVVFQA	0.979	0.7792	7	17
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	HLA-B15:07	INFQRKSVVVF	0.9982	0.5417	4	15
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	HLA-B15:34	FQRKSVVVF	0.9997	0.7847	6	15
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	HLA-B15:125	FQRKSVVVF	0.9997	0.7847	6	15
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	HLA-B15:33	FQRKSVVVF	0.9997	0.7847	6	15
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	HLA-B15:135	FQRKSVVVF	0.9997	0.7847	6	15
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	HLA-B15:27	FQRKSVVVF	0.9997	0.8234	6	15
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	HLA-B35:43	FQRKSVVVF	0.9996	0.7349	6	15
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	HLA-B15:08	FQRKSVVVF	0.9996	0.739	6	15
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	HLA-B15:11	FQRKSVVVF	0.9996	0.7436	6	15
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	HLA-B15:24	FQRKSVVVF	0.9995	0.6502	6	15
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	HLA-B15:50	FQRKSVVVF	0.9995	0.7979	6	15
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	HLA-B15:53	FQRKSVVVF	0.9994	0.7577	6	15
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	HLA-B15:35	FQRKSVVVF	0.9989	0.7759	6	15
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	HLA-B15:54	FQRKSVVVF	0.9985	0.745	6	15
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	HLA-C12:03	FQRKSVVVF	0.9923	0.9624	6	15
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	HLA-B15:12	FQRKSVVVF	0.9822	0.7882	6	15
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	HLA-C12:02	FQRKSVVVF	0.9773	0.9481	6	15
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	HLA-B15:39	FQRKSVVVF	0.9757	0.7044	6	15
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	HLA-B15:73	FQRKSVVVF	0.9719	0.5995	6	15
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	HLA-B15:30	FQRKSVVVF	0.9166	0.5519	6	15
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	HLA-C16:04	FQRKSVVVF	0.8797	0.9705	6	15
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	HLA-C03:02	FQRKSVVVF	0.8615	0.9046	6	15
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	HLA-C03:67	FQRKSVVVF	0.7693	0.8832	6	15
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	HLA-B35:20	FQRKSVVVF	0.7662	0.877	6	15
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	HLA-B39:02	FQRKSVVVF	0.7031	0.5913	6	15
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	HLA-C07:17	FQRKSVVVF	0.696	0.9389	6	15
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	HLA-C07:02	FQRKSVVVF	0.6897	0.8534	6	15
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	HLA-B15:20	FQRKSVVVF	0.6843	0.87	6	15
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	HLA-C03:05	FQRKSVVVF	0.6618	0.8049	6	15
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	HLA-C02:02	FQRKSVVVF	0.6361	0.9557	6	15
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	HLA-C02:10	FQRKSVVVF	0.6361	0.9557	6	15
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	HLA-B35:28	FQRKSVVVF	0.6328	0.8697	6	15
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	HLA-B18:04	FQRKSVVVF	0.5863	0.8402	6	15
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	HLA-B48:02	FQRKSVVVF	0.5644	0.8586	6	15
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	HLA-B18:07	FQRKSVVVF	0.494	0.7627	6	15
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	HLA-B18:06	FQRKSVVVF	0.4844	0.8346	6	15
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	HLA-B18:08	FQRKSVVVF	0.4184	0.6401	6	15
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	HLA-B18:03	FQRKSVVVF	0.3917	0.8157	6	15
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	HLA-B15:54	NFQRKSVVVF	0.9611	0.6022	5	15
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	HLA-B15:35	NFQRKSVVVF	0.9384	0.6554	5	15
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	HLA-B15:34	NFQRKSVVVF	0.9358	0.7031	5	15
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	HLA-B15:125	NFQRKSVVVF	0.9358	0.7031	5	15
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	HLA-B15:33	NFQRKSVVVF	0.9358	0.7031	5	15
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	HLA-B15:27	NFQRKSVVVF	0.934	0.7666	5	15
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	HLA-B15:50	NFQRKSVVVF	0.9296	0.8381	5	15
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	HLA-B15:12	NFQRKSVVVF	0.9161	0.7147	5	15
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	HLA-B15:24	NFQRKSVVVF	0.9095	0.5834	5	15
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	HLA-B15:35	INFQRKSVVVF	0.9977	0.6829	4	15
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	HLA-B52:01	FQRKSVVV	0.7899	0.9085	6	14
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	HLA-B08:09	NFQRKSVVV	0.9755	0.6487	5	14
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	HLA-A02:38	VVVPWPVVV	0.9721	0.6597	11	20
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	HLA-A02:21	VVVPWPVVV	0.9623	0.5768	11	20
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	HLA-B51:02	VVVPWPVVV	0.941	0.5635	11	20
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	HLA-A02:04	VVVPWPVVV	0.9337	0.5752	11	20
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	HLA-A02:13	VVVPWPVVV	0.9244	0.6769	11	20
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	HLA-A02:17	VVVPWPVVV	0.9165	0.6365	11	20
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	HLA-A02:27	VVVPWPVVV	0.8966	0.533	11	20
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	HLA-B52:01	VVVPWPVVV	0.8706	0.9836	11	20
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	HLA-B13:02	VVVPWPVVV	0.5112	0.9074	11	20
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	HLA-B15:04	FQRKSVVV	0.9915	0.8999	6	14
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	HLA-C01:17	VVPWPVVV	0.9776	0.9644	12	20
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	HLA-C01:30	VVPWPVVV	0.9729	0.9643	12	20
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	HLA-C15:06	VVVPWPVVV	0.9986	0.8425	11	20
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	HLA-C04:06	VVVPWPVVV	0.9984	0.9773	11	20
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	HLA-C03:07	VVVPWPVVV	0.9981	0.9703	11	20
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	HLA-C15:04	VVVPWPVVV	0.9978	0.8417	11	20
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	HLA-C03:19	VVVPWPVVV	0.9839	0.9878	11	20
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	HLA-C03:08	VVVPWPVVV	0.977	0.8051	11	20
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	HLA-C06:03	VVVPWPVVV	0.9764	0.9914	11	20
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	HLA-C12:04	VVVPWPVVV	0.9753	0.9933	11	20
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	HLA-C12:12	VVVPWPVVV	0.9406	0.9334	11	20
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	HLA-C08:13	VVVPWPVVV	0.9404	0.9935	11	20
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	HLA-C08:04	VVVPWPVVV	0.9404	0.9935	11	20
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	HLA-B15:04	FQRKSVVVP	0.918	0.7119	6	15
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	HLA-B51:07	VVVPWPVVV	0.8574	0.9811	11	20
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	HLA-C07:05	QRKSVVVPW	0.7621	0.8902	7	16
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	HLA-C02:06	VVVPWPVVV	0.7154	0.9527	11	20
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	HLA-C08:03	VVVPWPVVV	0.5459	0.9916	11	20
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	HLA-C03:14	VVVPWPVVV	0.4125	0.9736	11	20
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	HLA-C01:02	VVPWPVVV	0.9731	0.9651	12	20
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	HLA-C01:03	VVPWPVVV	0.9303	0.9422	12	20
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	HLA-C15:02	VVVPWPVVV	0.9991	0.8556	11	20
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	HLA-C15:05	VVVPWPVVV	0.9988	0.9136	11	20
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	HLA-C15:09	VVVPWPVVV	0.9978	0.8417	11	20
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	HLA-C03:05	VVVPWPVVV	0.9878	0.9181	11	20
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	HLA-C03:17	VVVPWPVVV	0.986	0.9582	11	20
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	HLA-C03:06	VVVPWPVVV	0.986	0.9879	11	20
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	HLA-A69:01	SVVVPWPVV	0.9766	0.5552	10	19
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	HLA-C03:03	VVVPWPVVV	0.9711	0.9835	11	20
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	HLA-C03:04	VVVPWPVVV	0.9711	0.9835	11	20
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	HLA-C16:02	VVVPWPVVV	0.9705	0.9948	11	20
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	HLA-A02:14	VVVPWPVVV	0.965	0.5046	11	20
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	HLA-A02:03	VVVPWPVVV	0.9643	0.5493	11	20
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	HLA-C16:04	VVVPWPVVV	0.9639	0.977	11	20
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	HLA-A02:06	VVVPWPVVV	0.9623	0.5768	11	20
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	HLA-C06:17	VVVPWPVVV	0.9519	0.9928	11	20
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	HLA-C06:02	VVVPWPVVV	0.9519	0.9928	11	20
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	HLA-C12:03	VVVPWPVVV	0.926	0.9844	11	20
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	HLA-A69:01	VVVPWPVVV	0.9252	0.6608	11	20
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	HLA-B51:13	VVVPWPVVV	0.878	0.6781	11	20
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	HLA-B51:14	VVVPWPVVV	0.87	0.613	11	20
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	HLA-C12:02	VVVPWPVVV	0.7316	0.9588	11	20
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	HLA-B51:21	VVVPWPVVV	0.646	0.5729	11	20
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	HLA-B08:12	NFQRKSVVV	0.6325	0.7257	5	14
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	HLA-C02:10	VVVPWPVVV	0.5879	0.9675	11	20
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	HLA-C02:02	VVVPWPVVV	0.5879	0.9675	11	20
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	HLA-C17:01	VVVPWPVVV	0.5495	0.9836	11	20
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	HLA-C08:01	VVVPWPVVV	0.5459	0.9916	11	20
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	HLA-C07:22	QRKSVVVPW	0.5434	0.5254	7	16
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	HLA-C06:08	VVVPWPVVV	0.503	0.9933	11	20
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	HLA-B15:24	FQRKSVVVPW	0.9989	0.9014	6	16

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Potential FusionNeoAntigen Information of TAF2-ALDH16A1 in HLA II

TAF2-ALDH16A1_120843916_49967110.msa
TAF2-ALDH16A1_120843917_49967384.msa

Potential FusionNeoAntigen Information
* We used NetMHCIIpan v4.1 (%rank<0.5).

Fusion gene	Hchr	Hbp	Tgene	Tchr	Tbp	HLA II	FusionNeoAntigen peptide	Neoantigen start (at BP 13)	Neoantigen end (at BP 13)
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-0819	RKSVVVFQAGDVPSE	8	23
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-0834	RKSVVVFQAGDVPSE	8	23
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-0906	RKSVVVFQAGDVPSE	8	23
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1203	RKSVVVFQAGDVPSE	8	23
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1203	QRKSVVVFQAGDVPS	7	22
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1208	RKSVVVFQAGDVPSE	8	23
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1208	QRKSVVVFQAGDVPS	7	22
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1213	RKSVVVFQAGDVPSE	8	23
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1215	RKSVVVFQAGDVPSE	8	23
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1218	RKSVVVFQAGDVPSE	8	23
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1219	RKSVVVFQAGDVPSE	8	23
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1219	QRKSVVVFQAGDVPS	7	22
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1220	RKSVVVFQAGDVPSE	8	23
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1221	RKSVVVFQAGDVPSE	8	23
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1223	RKSVVVFQAGDVPSE	8	23
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1377	RKSVVVFQAGDVPSE	8	23
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1416	INNINFQRKSVVVFQ	1	16
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1418	INNINFQRKSVVVFQ	1	16
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1429	INNINFQRKSVVVFQ	1	16
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1431	RKSVVVFQAGDVPSE	8	23
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1431	INNINFQRKSVVVFQ	1	16
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1431	QRKSVVVFQAGDVPS	7	22
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1432	INNINFQRKSVVVFQ	1	16
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1432	CINNINFQRKSVVVF	0	15
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1438	INNINFQRKSVVVFQ	1	16
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1450	INNINFQRKSVVVFQ	1	16
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1455	INNINFQRKSVVVFQ	1	16
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1465	INNINFQRKSVVVFQ	1	16
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1475	INNINFQRKSVVVFQ	1	16
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1481	INNINFQRKSVVVFQ	1	16
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1482	INNINFQRKSVVVFQ	1	16
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1499	INNINFQRKSVVVFQ	1	16
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1501	RKSVVVFQAGDVPSE	8	23
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1501	QRKSVVVFQAGDVPS	7	22
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1502	RKSVVVFQAGDVPSE	8	23
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1503	RKSVVVFQAGDVPSE	8	23
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1503	QRKSVVVFQAGDVPS	7	22
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1504	RKSVVVFQAGDVPSE	8	23
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1504	QRKSVVVFQAGDVPS	7	22
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1505	RKSVVVFQAGDVPSE	8	23
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1505	QRKSVVVFQAGDVPS	7	22
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1506	RKSVVVFQAGDVPSE	8	23
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1506	QRKSVVVFQAGDVPS	7	22
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1507	RKSVVVFQAGDVPSE	8	23
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1507	QRKSVVVFQAGDVPS	7	22
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1508	RKSVVVFQAGDVPSE	8	23
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1509	RKSVVVFQAGDVPSE	8	23
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1509	QRKSVVVFQAGDVPS	7	22
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1510	RKSVVVFQAGDVPSE	8	23
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1510	QRKSVVVFQAGDVPS	7	22
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1512	RKSVVVFQAGDVPSE	8	23
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1512	QRKSVVVFQAGDVPS	7	22
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1512	FQRKSVVVFQAGDVP	6	21
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1513	RKSVVVFQAGDVPSE	8	23
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1513	QRKSVVVFQAGDVPS	7	22
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1514	RKSVVVFQAGDVPSE	8	23
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1515	RKSVVVFQAGDVPSE	8	23
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1516	RKSVVVFQAGDVPSE	8	23
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1516	QRKSVVVFQAGDVPS	7	22
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1518	RKSVVVFQAGDVPSE	8	23
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1518	QRKSVVVFQAGDVPS	7	22
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1519	RKSVVVFQAGDVPSE	8	23
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1520	RKSVVVFQAGDVPSE	8	23
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1520	QRKSVVVFQAGDVPS	7	22
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1521	RKSVVVFQAGDVPSE	8	23
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1521	QRKSVVVFQAGDVPS	7	22
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1521	FQRKSVVVFQAGDVP	6	21
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1521	KSVVVFQAGDVPSER	9	24
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1522	RKSVVVFQAGDVPSE	8	23
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1522	QRKSVVVFQAGDVPS	7	22
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1523	RKSVVVFQAGDVPSE	8	23
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1523	QRKSVVVFQAGDVPS	7	22
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1524	RKSVVVFQAGDVPSE	8	23
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1524	QRKSVVVFQAGDVPS	7	22
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1525	RKSVVVFQAGDVPSE	8	23
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1526	RKSVVVFQAGDVPSE	8	23
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1527	RKSVVVFQAGDVPSE	8	23
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1528	RKSVVVFQAGDVPSE	8	23
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1528	QRKSVVVFQAGDVPS	7	22
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1529	RKSVVVFQAGDVPSE	8	23
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1529	QRKSVVVFQAGDVPS	7	22
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1530	RKSVVVFQAGDVPSE	8	23
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1531	RKSVVVFQAGDVPSE	8	23
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1532	RKSVVVFQAGDVPSE	8	23
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1532	QRKSVVVFQAGDVPS	7	22
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1533	RKSVVVFQAGDVPSE	8	23
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1533	QRKSVVVFQAGDVPS	7	22
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1535	RKSVVVFQAGDVPSE	8	23
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1535	QRKSVVVFQAGDVPS	7	22
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1536	RKSVVVFQAGDVPSE	8	23
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1536	QRKSVVVFQAGDVPS	7	22
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1537	RKSVVVFQAGDVPSE	8	23
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1537	QRKSVVVFQAGDVPS	7	22
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1538	RKSVVVFQAGDVPSE	8	23
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1539	RKSVVVFQAGDVPSE	8	23
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1540	RKSVVVFQAGDVPSE	8	23
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1540	QRKSVVVFQAGDVPS	7	22
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1541	RKSVVVFQAGDVPSE	8	23
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1541	QRKSVVVFQAGDVPS	7	22
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1542	RKSVVVFQAGDVPSE	8	23
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1542	QRKSVVVFQAGDVPS	7	22
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1543	RKSVVVFQAGDVPSE	8	23
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1543	QRKSVVVFQAGDVPS	7	22
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1544	RKSVVVFQAGDVPSE	8	23
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1545	RKSVVVFQAGDVPSE	8	23
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1545	QRKSVVVFQAGDVPS	7	22
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1546	RKSVVVFQAGDVPSE	8	23
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1546	QRKSVVVFQAGDVPS	7	22
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1547	RKSVVVFQAGDVPSE	8	23
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1548	RKSVVVFQAGDVPSE	8	23
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1548	QRKSVVVFQAGDVPS	7	22
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1549	RKSVVVFQAGDVPSE	8	23
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1549	QRKSVVVFQAGDVPS	7	22
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1610	RKSVVVFQAGDVPSE	8	23
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1615	RKSVVVFQAGDVPSE	8	23
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB1-1615	QRKSVVVFQAGDVPS	7	22
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB4-0101	KSVVVFQAGDVPSER	9	24
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB4-0103	KSVVVFQAGDVPSER	9	24
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB4-0104	KSVVVFQAGDVPSER	9	24
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB4-0106	KSVVVFQAGDVPSER	9	24
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB4-0107	KSVVVFQAGDVPSER	9	24
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB4-0108	KSVVVFQAGDVPSER	9	24
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB5-0202	RKSVVVFQAGDVPSE	8	23
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB5-0202	QRKSVVVFQAGDVPS	7	22
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB5-0203	RKSVVVFQAGDVPSE	8	23
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB5-0204	RKSVVVFQAGDVPSE	8	23
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB5-0204	QRKSVVVFQAGDVPS	7	22
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB5-0205	RKSVVVFQAGDVPSE	8	23
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	437	DRB5-0205	QRKSVVVFQAGDVPS	7	22
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-0437	RKSVVVPWPVVVASP	8	23
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-0437	KSVVVPWPVVVASPF	9	24
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-0437	QRKSVVVPWPVVVAS	7	22
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-0442	RKSVVVPWPVVVASP	8	23
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-0453	RKSVVVPWPVVVASP	8	23
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-0453	KSVVVPWPVVVASPF	9	24
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-0458	RKSVVVPWPVVVASP	8	23
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-0458	KSVVVPWPVVVASPF	9	24
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-0465	RKSVVVPWPVVVASP	8	23
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-0465	KSVVVPWPVVVASPF	9	24
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-0473	RKSVVVPWPVVVASP	8	23
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-0473	KSVVVPWPVVVASPF	9	24
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1113	CINNINFQRKSVVVP	0	15
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1117	CINNINFQRKSVVVP	0	15
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1152	CINNINFQRKSVVVP	0	15
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1343	CINNINFQRKSVVVP	0	15
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1354	CINNINFQRKSVVVP	0	15
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1354	INNINFQRKSVVVPW	1	16
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1377	CINNINFQRKSVVVP	0	15
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1401	CINNINFQRKSVVVP	0	15
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1401	INNINFQRKSVVVPW	1	16
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1404	CINNINFQRKSVVVP	0	15
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1405	CINNINFQRKSVVVP	0	15
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1406	CINNINFQRKSVVVP	0	15
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1408	CINNINFQRKSVVVP	0	15
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1411	CINNINFQRKSVVVP	0	15
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1416	CINNINFQRKSVVVP	0	15
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1416	INNINFQRKSVVVPW	1	16
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1418	CINNINFQRKSVVVP	0	15
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1418	INNINFQRKSVVVPW	1	16
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1420	CINNINFQRKSVVVP	0	15
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1423	CINNINFQRKSVVVP	0	15
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1426	CINNINFQRKSVVVP	0	15
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1426	INNINFQRKSVVVPW	1	16
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1428	CINNINFQRKSVVVP	0	15
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1429	CINNINFQRKSVVVP	0	15
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1429	INNINFQRKSVVVPW	1	16
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1431	CINNINFQRKSVVVP	0	15
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1431	INNINFQRKSVVVPW	1	16
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1432	CINNINFQRKSVVVP	0	15
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1432	INNINFQRKSVVVPW	1	16
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1434	CINNINFQRKSVVVP	0	15
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1435	CINNINFQRKSVVVP	0	15
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1437	CINNINFQRKSVVVP	0	15
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1438	CINNINFQRKSVVVP	0	15
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1438	INNINFQRKSVVVPW	1	16
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1443	CINNINFQRKSVVVP	0	15
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1445	CINNINFQRKSVVVP	0	15
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1450	CINNINFQRKSVVVP	0	15
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1450	INNINFQRKSVVVPW	1	16
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1454	CINNINFQRKSVVVP	0	15
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1454	INNINFQRKSVVVPW	1	16
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1455	CINNINFQRKSVVVP	0	15
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1455	INNINFQRKSVVVPW	1	16
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1456	CINNINFQRKSVVVP	0	15
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1457	RKSVVVPWPVVVASP	8	23
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1457	KSVVVPWPVVVASPF	9	24
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1457	QRKSVVVPWPVVVAS	7	22
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1458	CINNINFQRKSVVVP	0	15
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1458	INNINFQRKSVVVPW	1	16
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1459	CINNINFQRKSVVVP	0	15
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1460	CINNINFQRKSVVVP	0	15
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1460	INNINFQRKSVVVPW	1	16
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1461	CINNINFQRKSVVVP	0	15
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1462	CINNINFQRKSVVVP	0	15
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1462	INNINFQRKSVVVPW	1	16
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1465	CINNINFQRKSVVVP	0	15
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1465	INNINFQRKSVVVPW	1	16
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1470	CINNINFQRKSVVVP	0	15
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1471	CINNINFQRKSVVVP	0	15
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1474	CINNINFQRKSVVVP	0	15
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1475	CINNINFQRKSVVVP	0	15
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1475	INNINFQRKSVVVPW	1	16
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1481	CINNINFQRKSVVVP	0	15
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1481	INNINFQRKSVVVPW	1	16
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1482	CINNINFQRKSVVVP	0	15
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1482	INNINFQRKSVVVPW	1	16
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1483	CINNINFQRKSVVVP	0	15
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1486	CINNINFQRKSVVVP	0	15
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1486	INNINFQRKSVVVPW	1	16
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1487	CINNINFQRKSVVVP	0	15
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1487	INNINFQRKSVVVPW	1	16
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1488	CINNINFQRKSVVVP	0	15
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1488	INNINFQRKSVVVPW	1	16
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1490	CINNINFQRKSVVVP	0	15
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1490	INNINFQRKSVVVPW	1	16
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1491	CINNINFQRKSVVVP	0	15
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1495	CINNINFQRKSVVVP	0	15
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1496	CINNINFQRKSVVVP	0	15
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1497	CINNINFQRKSVVVP	0	15
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1497	INNINFQRKSVVVPW	1	16
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1499	CINNINFQRKSVVVP	0	15
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1499	INNINFQRKSVVVPW	1	16
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1521	KSVVVPWPVVVASPF	9	24
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	437	DRB1-1521	RKSVVVPWPVVVASP	8	23

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Fusion breakpoint peptide structures of TAF2-ALDH16A1

3D structures of the fusion breakpoint peptide of 14AA sequence that have potential fusion neoantigens
* The minimum length of the amino acid sequence in RoseTTAFold is 14AA. Here, we predicted the 14AA fusion protein breakpoint sequence not the fusion neoantigen peptide, which is shorter than 14 AA.

File name	BPseq	Hgene	Tgene	Hchr	Hbp	Tchr	Tbp	AAlen
2529	FQRKSVVVFQAGDV	TAF2	ALDH16A1	chr8	120843916	chr19	49967110	437

File name	BPseq	Hgene	Tgene	Hchr	Hbp	Tchr	Tbp	AAlen
2530	FQRKSVVVPWPVVV	TAF2	ALDH16A1	chr8	120843917	chr19	49967384	437

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Filtering FusionNeoAntigens Through Checking the Interaction with HLAs in 3D of TAF2-ALDH16A1

Virtual screening between 25 HLAs (from PDB) and FusionNeoAntigens
* We used Glide to predict the interaction between HLAs and neoantigens.

HLA allele	PDB ID	File name	BPseq	Docking score	Glide score
HLA-B14:02	3BVN	2529	FQRKSVVVFQAGDV	-7.9962	-8.1096
HLA-B14:02	3BVN	2529	FQRKSVVVFQAGDV	-5.70842	-6.74372
HLA-B52:01	3W39	2529	FQRKSVVVFQAGDV	-6.83737	-6.95077
HLA-B52:01	3W39	2529	FQRKSVVVFQAGDV	-4.4836	-5.5189
HLA-A11:01	4UQ2	2529	FQRKSVVVFQAGDV	-10.0067	-10.1201
HLA-A11:01	4UQ2	2529	FQRKSVVVFQAGDV	-9.03915	-10.0745
HLA-A24:02	5HGA	2529	FQRKSVVVFQAGDV	-6.56204	-6.67544
HLA-A24:02	5HGA	2529	FQRKSVVVFQAGDV	-5.42271	-6.45801
HLA-B44:05	3DX8	2529	FQRKSVVVFQAGDV	-7.85648	-8.89178
HLA-B44:05	3DX8	2529	FQRKSVVVFQAGDV	-5.3978	-5.5112
HLA-A02:01	6TDR	2529	FQRKSVVVFQAGDV	-3.37154	-4.40684
HLA-B14:02	3BVN	2530	FQRKSVVVPWPVVV	-7.10743	-7.22083
HLA-B14:02	3BVN	2530	FQRKSVVVPWPVVV	-3.79488	-4.83018
HLA-B52:01	3W39	2530	FQRKSVVVPWPVVV	-6.78681	-6.90021
HLA-B52:01	3W39	2530	FQRKSVVVPWPVVV	-3.75119	-4.78649
HLA-A11:01	4UQ2	2530	FQRKSVVVPWPVVV	-10.1888	-11.2241
HLA-A11:01	4UQ2	2530	FQRKSVVVPWPVVV	-6.59241	-6.70581
HLA-A24:02	5HGA	2530	FQRKSVVVPWPVVV	-8.29771	-9.33301
HLA-A24:02	5HGA	2530	FQRKSVVVPWPVVV	-8.23185	-8.34525
HLA-B44:05	3DX8	2530	FQRKSVVVPWPVVV	-7.25218	-7.36558
HLA-B44:05	3DX8	2530	FQRKSVVVPWPVVV	-3.76181	-4.79711
HLA-A02:01	6TDR	2530	FQRKSVVVPWPVVV	-2.73959	-3.77489

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Vaccine Design for the FusionNeoAntigens of TAF2-ALDH16A1

mRNA and peptide sequences of FusionNeoAntigens that have potential interaction with HLA-Is.

Fusion gene	Hchr	Hbp	Tchr	Tbp	Start in +/-13AA	End in +/-13AA	FusionNeoAntigen peptide sequence	FusionNeoAntigen RNA sequence
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	4	15	INFQRKSVVVF	ATAAATTTCCAGAGAAAATCTGTTGTGGTGTTC
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	5	15	NFQRKSVVVF	AATTTCCAGAGAAAATCTGTTGTGGTGTTC
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	6	15	FQRKSVVVF	TTCCAGAGAAAATCTGTTGTGGTGTTC
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	7	15	QRKSVVVF	CAGAGAAAATCTGTTGTGGTGTTC
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	7	17	QRKSVVVFQA	CAGAGAAAATCTGTTGTGGTGTTCCAGGCT
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	10	19	SVVVPWPVV	TCTGTTGTGGTGCCGTGGCCTGTGGTC
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	11	20	VVVPWPVVV	GTTGTGGTGCCGTGGCCTGTGGTCGTG
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	12	20	VVPWPVVV	GTGGTGCCGTGGCCTGTGGTCGTG
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	5	14	NFQRKSVVV	AATTTCCAGAGAAAATCTGTTGTGGTG
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	6	14	FQRKSVVV	TTCCAGAGAAAATCTGTTGTGGTG
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	6	15	FQRKSVVVP	TTCCAGAGAAAATCTGTTGTGGTGCCG
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	6	16	FQRKSVVVPW	TTCCAGAGAAAATCTGTTGTGGTGCCGTGG
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	7	16	QRKSVVVPW	CAGAGAAAATCTGTTGTGGTGCCGTGG

mRNA and peptide sequences of FusionNeoAntigens that have potential interaction with HLA-IIs.

Fusion gene	Hchr	Hbp	Tchr	Tbp	Start in +/-13AA	End in +/-13AA	FusionNeoAntigen peptide	FusionNEoAntigen RNA sequence
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	0	15	CINNINFQRKSVVVF	TGCATCAACAACATAAATTTCCAGAGAAAATCTGTTGTGGTGTTC
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	1	16	INNINFQRKSVVVFQ	ATCAACAACATAAATTTCCAGAGAAAATCTGTTGTGGTGTTCCAG
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	6	21	FQRKSVVVFQAGDVP	TTCCAGAGAAAATCTGTTGTGGTGTTCCAGGCTGGTGATGTGCCT
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	7	22	QRKSVVVFQAGDVPS	CAGAGAAAATCTGTTGTGGTGTTCCAGGCTGGTGATGTGCCTTCG
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	8	23	RKSVVVFQAGDVPSE	AGAAAATCTGTTGTGGTGTTCCAGGCTGGTGATGTGCCTTCGGAA
TAF2-ALDH16A1	chr8	120843916	chr19	49967110	9	24	KSVVVFQAGDVPSER	AAATCTGTTGTGGTGTTCCAGGCTGGTGATGTGCCTTCGGAACGC
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	0	15	CINNINFQRKSVVVP	TGCATCAACAACATAAATTTCCAGAGAAAATCTGTTGTGGTGCCG
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	1	16	INNINFQRKSVVVPW	ATCAACAACATAAATTTCCAGAGAAAATCTGTTGTGGTGCCGTGG
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	7	22	QRKSVVVPWPVVVAS	CAGAGAAAATCTGTTGTGGTGCCGTGGCCTGTGGTCGTGGCCTCC
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	8	23	RKSVVVPWPVVVASP	AGAAAATCTGTTGTGGTGCCGTGGCCTGTGGTCGTGGCCTCCCCC
TAF2-ALDH16A1	chr8	120843917	chr19	49967384	9	24	KSVVVPWPVVVASPF	AAATCTGTTGTGGTGCCGTGGCCTGTGGTCGTGGCCTCCCCCTTC

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Information of the samples that have these potential fusion neoantigens of TAF2-ALDH16A1

These samples were reported as having these fusion breakpoints. For individual breakpoints, we checked the open reading frames considering multiple gene isoforms and chose the in-frame fusion genes only. Then, we made fusion protein sequences and predicted the fusion neoantigens. These fusion-positive samples may have these potential fusion neoantigens.

Cancer type	Fusion gene	Hchr	Hbp	Henst	Tchr	Tbp	Tenst	Sample
BRCA	TAF2-ALDH16A1	chr8	120843917	ENST00000378164	chr19	49967384	ENST00000293350	TCGA-AC-A5XU-01A
BRCA	TAF2-ALDH16A1	chr8	120843916	ENST00000378164	chr19	49967110	ENST00000293350	TCGA-AC-A5XU

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Potential target of CAR-T therapy development for TAF2-ALDH16A1

Predicted 3D structure. We used RoseTTAFold.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, to provide the retention of the transmembrane domain, we only show the protein feature retention information of those transmembrane features

* Minus value of BPloci means that the break point is located before the CDS.

- In-frame and retained 'Transmembrane'.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Subcellular localization prediction of the transmembrane domain retained fusion proteins
* We used DeepLoc 1.0. The order of the X-axis of the barplot is as follows: Entry_ID, Localization, Type, Nucleus, Cytoplasm, Extracellular, Mitochondrion, Cell_membrane, Endoplasmic_reticulum, Plastid, Golgi.apparatus, Lysosome.Vacuole, Peroxisome. Y-axis is the output score of DeepLoc. Clicking the image will open a new tab with a large image.

Hgene

Hchr

Hbp

Henst

Tgene

Tchr

Tbp

Tenst

DeepLoc result

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Related Drugs to TAF2-ALDH16A1

Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)

Hgene

Tgene

Drug

Source

PMID

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Related Diseases to TAF2-ALDH16A1

Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)

Hgene

Tgene

Disease

Source

PMID

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source

	Fusion Gene and Fusion Protein Summary
	Fusion Amino Acid Sequences (multiple BPs and multiple gene isoforms)
	Fusion Protein Breakpoint Sequences - (for the Screening of the FusionNeoAntigens)
	Potential FusionNeoAntigens in HLA I - (netMHCpan v4.1 + deepHLApan v1.1)
	Potential FusionNeoAntigens in HLA II - (netMHCIIpan v4.1)
	Fusion Breakpoint 14 AA Peptide Structure - (RoseTTAFold)
	Filtering FusionNeoAntigens Through Checking the Interaction with HLAs in 3D - (Glide)
	Vaccine Design for the FusionNeoAntigens (RNA/protein sequences)
	Potential target of CAR-T therapy development
	Information on the samples that have these potential fusion neoantigens
	Fusion Protein Targeting Drugs - (Manual Curation)
	Fusion Protein Related diseases - (Manual Curation)