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Center for Computational Systems Medicine
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Fusion Gene and Fusion Protein Summary

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Fusion Amino Acid Sequences (multiple BPs and multiple gene isoforms)

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Fusion Protein Breakpoint Sequences - (for the Screening of the FusionNeoAntigens)

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Potential FusionNeoAntigens in HLA I - (netMHCpan v4.1 + deepHLApan v1.1)

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Potential FusionNeoAntigens in HLA II - (netMHCIIpan v4.1)

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Fusion Breakpoint 14 AA Peptide Structure - (RoseTTAFold)

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Filtering FusionNeoAntigens Through Checking the Interaction with HLAs in 3D - (Glide)

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Vaccine Design for the FusionNeoAntigens (RNA/protein sequences)

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Potential target of CAR-T therapy development

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Information on the samples that have these potential fusion neoantigens

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Fusion Protein Targeting Drugs - (Manual Curation)

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Fusion Protein Related diseases - (Manual Curation)

Fusion Protein:BAIAP2L1-GTF2I

Fusion Gene and Fusion Protein Summary

check button Fusion gene summary
Fusion partner gene informationFusion gene name: BAIAP2L1-GTF2I
FusionPDB ID: 8915
FusionGDB2.0 ID: 8915
HgeneTgene
Gene symbol

BAIAP2L1

GTF2I

Gene ID

55971

2969

Gene nameBAR/IMD domain containing adaptor protein 2 like 1general transcription factor IIi
SynonymsIRTKSBAP135|BTKAP1|DIWS|GTFII-I|IB291|SPIN|TFII-I|WBS|WBSCR6
Cytomap

7q21.3-q22.1

7q11.23

Type of geneprotein-codingprotein-coding
Descriptionbrain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1BAI1 associated protein 2 like 1BAI1-associated protein 2-like protein 1insulin receptor tyrosine kinase substrategeneral transcription factor II-IBTK-associated protein, 135kDBruton tyrosine kinase-associated protein 135SRF-Phox1-interacting proteinWilliams-Beuren syndrome chromosome region 6
Modification date2020031320200313
UniProtAcc

Q9UHR4

Main function of 5'-partner protein: FUNCTION: May function as adapter protein. Involved in the formation of clusters of actin bundles. Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection. {ECO:0000269|PubMed:17430976, ECO:0000269|PubMed:19366662, ECO:0000269|PubMed:22921828}.

Q6EKJ0

Main function of 5'-partner protein:
Ensembl transtripts involved in fusion geneENST idsENST00000005260, ENST00000462558, 
ENST00000438130, ENST00000443166, 
ENST00000324896, ENST00000346152, 
ENST00000353920, ENST00000416070, 
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)* DoF score20 X 13 X 9=234021 X 20 X 13=5460
# samples 2325
** MAII scorelog2(23/2340*10)=-3.34680276352639
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(25/5460*10)=-4.44890095114513
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Fusion gene context

PubMed: BAIAP2L1 [Title/Abstract] AND GTF2I [Title/Abstract] AND fusion [Title/Abstract]

Fusion neoantigen context

PubMed: BAIAP2L1 [Title/Abstract] AND GTF2I [Title/Abstract] AND neoantigen [Title/Abstract]

Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)BAIAP2L1(97991668)-GTF2I(74163604), # samples:1
BAIAP2L1(97991669)-GTF2I(74163605), # samples:1
Anticipated loss of major functional domain due to fusion event.BAIAP2L1-GTF2I seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
BAIAP2L1-GTF2I seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneBAIAP2L1

GO:0009617

response to bacterium

19366662

HgeneBAIAP2L1

GO:0030838

positive regulation of actin filament polymerization

21098279

TgeneGTF2I

GO:0016525

negative regulation of angiogenesis

19242469



check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr7:97991668/chr7:74163604)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonRetention analysis results of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features, are available here.

check buttonFusion gene breakpoints across BAIAP2L1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across GTF2I (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure


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Fusion Amino Acid Sequences


check buttonFusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000005260BAIAP2L1chr797991668-ENST00000324896GTF2Ichr774163604+2266343331103356
ENST00000005260BAIAP2L1chr797991668-ENST00000353920GTF2Ichr774163604+2266343331103356
ENST00000005260BAIAP2L1chr797991668-ENST00000346152GTF2Ichr774163604+2266343331103356
ENST00000005260BAIAP2L1chr797991668-ENST00000416070GTF2Ichr774163604+2270343331103356
ENST00000005260BAIAP2L1chr797991669-ENST00000324896GTF2Ichr774163605+2266343331103356
ENST00000005260BAIAP2L1chr797991669-ENST00000353920GTF2Ichr774163605+2266343331103356
ENST00000005260BAIAP2L1chr797991669-ENST00000346152GTF2Ichr774163605+2266343331103356
ENST00000005260BAIAP2L1chr797991669-ENST00000416070GTF2Ichr774163605+2270343331103356

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000005260ENST00000324896BAIAP2L1chr797991668-GTF2Ichr774163604+0.0007124280.99928755
ENST00000005260ENST00000353920BAIAP2L1chr797991668-GTF2Ichr774163604+0.0007124280.99928755
ENST00000005260ENST00000346152BAIAP2L1chr797991668-GTF2Ichr774163604+0.0007124280.99928755
ENST00000005260ENST00000416070BAIAP2L1chr797991668-GTF2Ichr774163604+0.0007135150.9992865
ENST00000005260ENST00000324896BAIAP2L1chr797991669-GTF2Ichr774163605+0.0007124280.99928755
ENST00000005260ENST00000353920BAIAP2L1chr797991669-GTF2Ichr774163605+0.0007124280.99928755
ENST00000005260ENST00000346152BAIAP2L1chr797991669-GTF2Ichr774163605+0.0007124280.99928755
ENST00000005260ENST00000416070BAIAP2L1chr797991669-GTF2Ichr774163605+0.0007135150.9992865

check button Predicted full-length fusion amino acid sequences. For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among all the predicted ones.

Get the fusion protein sequences from here.

Fusion protein sequence information is available in the fasta format.
>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

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Fusion Protein Breakpoint Sequences for BAIAP2L1-GTF2I

check button +/-13 AA sequence from the breakpoints of the fusion protein sequences.
HgeneHchrHbpTgeneTchrTbpLength(fusion protein)BP in fusion proteinPeptide
BAIAP2L1chr797991668GTF2Ichr774163604343103LINLGKNYEKAVNGEALGLKQAVKVP
BAIAP2L1chr797991668GTF2Ichr774163604343105NLGKNYEKAVNGEALGLKQAVKVPFA
BAIAP2L1chr797991669GTF2Ichr774163605343103LINLGKNYEKAVNGEALGLKQAVKVP
BAIAP2L1chr797991669GTF2Ichr774163605343105NLGKNYEKAVNGEALGLKQAVKVPFA

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Potential FusionNeoAntigen Information of BAIAP2L1-GTF2I in HLA I

check button Multiple sequence alignments of the potential FusionNeoAntigens per fusion breakpoints. If the MSA is empty, then it means that there were predicted fusion neoantigens in this fusion breakpoint, but those predicted fusion neoantigens were not across the breakpoint, which is not fusion-specific.
BAIAP2L1-GTF2I_97991668_74163604.msa

check button Potential FusionNeoAntigen Information
* We used NetMHCpan v4.1 (%rank<0.5) and deepHLApan v1.1 (immunogenic score>0.5)
Fusion geneHchrHbpTgeneTchrTbpHLA IFusionNeoAntigen peptideBinding scoreImmunogenic scoreNeoantigen start (at BP 13)Neoantigen end (at BP 13)
BAIAP2L1-GTF2Ichr797991668chr774163604343HLA-B39:01EKAVNGEAL0.9920.8728615
BAIAP2L1-GTF2Ichr797991668chr774163604343HLA-B45:01YEKAVNGEA0.98960.7105514
BAIAP2L1-GTF2Ichr797991668chr774163604343HLA-B50:02YEKAVNGEA0.97930.6305514
BAIAP2L1-GTF2Ichr797991668chr774163604343HLA-B15:10EKAVNGEAL0.83820.5809615
BAIAP2L1-GTF2Ichr797991668chr774163604343HLA-B50:01YEKAVNGEA0.58120.7549514
BAIAP2L1-GTF2Ichr797991668chr774163604343HLA-B41:01YEKAVNGEA0.56860.7027514
BAIAP2L1-GTF2Ichr797991668chr774163604343HLA-B15:37EKAVNGEAL0.47170.5899615
BAIAP2L1-GTF2Ichr797991668chr774163604343HLA-A11:03AVNGEALGLK0.99940.6654818
BAIAP2L1-GTF2Ichr797991668chr774163604343HLA-A03:12AVNGEALGLK0.99510.6712818
BAIAP2L1-GTF2Ichr797991668chr774163604343HLA-A03:25AVNGEALGLK0.99510.6256818
BAIAP2L1-GTF2Ichr797991668chr774163604343HLA-A11:04AVNGEALGLK0.99390.647818
BAIAP2L1-GTF2Ichr797991668chr774163604343HLA-B45:01NGEALGLKQA0.85410.91251020
BAIAP2L1-GTF2Ichr797991668chr774163604343HLA-B50:02NGEALGLKQA0.83440.79711020
BAIAP2L1-GTF2Ichr797991668chr774163604343HLA-B40:06YEKAVNGEA0.99870.5223514
BAIAP2L1-GTF2Ichr797991668chr774163604343HLA-B39:09EKAVNGEAL0.99220.5536615
BAIAP2L1-GTF2Ichr797991668chr774163604343HLA-B39:05EKAVNGEAL0.9820.8376615
BAIAP2L1-GTF2Ichr797991668chr774163604343HLA-B14:03EKAVNGEAL0.3130.7773615
BAIAP2L1-GTF2Ichr797991668chr774163604343HLA-A11:01AVNGEALGLK0.99930.596818
BAIAP2L1-GTF2Ichr797991668chr774163604343HLA-A03:01AVNGEALGLK0.99510.6256818
BAIAP2L1-GTF2Ichr797991668chr774163604343HLA-B39:08YEKAVNGEAL0.97190.5902515
BAIAP2L1-GTF2Ichr797991668chr774163604343HLA-B39:31EKAVNGEAL0.99280.8724615
BAIAP2L1-GTF2Ichr797991668chr774163604343HLA-B50:05YEKAVNGEA0.58120.7549514
BAIAP2L1-GTF2Ichr797991668chr774163604343HLA-B50:04YEKAVNGEA0.58120.7549514
BAIAP2L1-GTF2Ichr797991668chr774163604343HLA-B39:11EKAVNGEAL0.4510.579615
BAIAP2L1-GTF2Ichr797991668chr774163604343HLA-A11:02AVNGEALGLK0.99930.596818
BAIAP2L1-GTF2Ichr797991668chr774163604343HLA-B40:04YEKAVNGEAL0.99470.7251515
BAIAP2L1-GTF2Ichr797991668chr774163604343HLA-A03:02AVNGEALGLK0.99390.5639818

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Potential FusionNeoAntigen Information of BAIAP2L1-GTF2I in HLA II

check button Multiple sequence alignments of the potential FusionNeoAntigens per fusion breakpoints. If the MSA is empty, then it means that there were predicted fusion neoantigens in this fusion breakpoint, but those predicted fusion neoantigens were not across the breakpoint, which is not fusion-specific.
BAIAP2L1-GTF2I_97991668_74163604.msa

check button Potential FusionNeoAntigen Information
* We used NetMHCIIpan v4.1 (%rank<0.5).
Fusion geneHchrHbpTgeneTchrTbpHLA IIFusionNeoAntigen peptideNeoantigen start (at BP 13)Neoantigen end (at BP 13)
BAIAP2L1-GTF2Ichr797991668chr774163604343DRB1-0103GEALGLKQAVKVPFA1126
BAIAP2L1-GTF2Ichr797991668chr774163604343DRB1-0401LGKNYEKAVNGEALG116
BAIAP2L1-GTF2Ichr797991668chr774163604343DRB1-0401GKNYEKAVNGEALGL217
BAIAP2L1-GTF2Ichr797991668chr774163604343DRB1-0407LGKNYEKAVNGEALG116
BAIAP2L1-GTF2Ichr797991668chr774163604343DRB1-0407GKNYEKAVNGEALGL217
BAIAP2L1-GTF2Ichr797991668chr774163604343DRB1-0407NLGKNYEKAVNGEAL015
BAIAP2L1-GTF2Ichr797991668chr774163604343DRB1-0419LGKNYEKAVNGEALG116
BAIAP2L1-GTF2Ichr797991668chr774163604343DRB1-0419GKNYEKAVNGEALGL217
BAIAP2L1-GTF2Ichr797991668chr774163604343DRB1-0431LGKNYEKAVNGEALG116
BAIAP2L1-GTF2Ichr797991668chr774163604343DRB1-0431GKNYEKAVNGEALGL217
BAIAP2L1-GTF2Ichr797991668chr774163604343DRB1-0433LGKNYEKAVNGEALG116
BAIAP2L1-GTF2Ichr797991668chr774163604343DRB1-0433GKNYEKAVNGEALGL217
BAIAP2L1-GTF2Ichr797991668chr774163604343DRB1-0435LGKNYEKAVNGEALG116
BAIAP2L1-GTF2Ichr797991668chr774163604343DRB1-0435GKNYEKAVNGEALGL217
BAIAP2L1-GTF2Ichr797991668chr774163604343DRB1-0438LGKNYEKAVNGEALG116
BAIAP2L1-GTF2Ichr797991668chr774163604343DRB1-0438GKNYEKAVNGEALGL217
BAIAP2L1-GTF2Ichr797991668chr774163604343DRB1-0443LGKNYEKAVNGEALG116
BAIAP2L1-GTF2Ichr797991668chr774163604343DRB1-0443GKNYEKAVNGEALGL217
BAIAP2L1-GTF2Ichr797991668chr774163604343DRB1-0447LGKNYEKAVNGEALG116
BAIAP2L1-GTF2Ichr797991668chr774163604343DRB1-0447GKNYEKAVNGEALGL217
BAIAP2L1-GTF2Ichr797991668chr774163604343DRB1-0454LGKNYEKAVNGEALG116
BAIAP2L1-GTF2Ichr797991668chr774163604343DRB1-0454GKNYEKAVNGEALGL217
BAIAP2L1-GTF2Ichr797991668chr774163604343DRB1-0461LGKNYEKAVNGEALG116
BAIAP2L1-GTF2Ichr797991668chr774163604343DRB1-0461GKNYEKAVNGEALGL217
BAIAP2L1-GTF2Ichr797991668chr774163604343DRB1-0463LGKNYEKAVNGEALG116
BAIAP2L1-GTF2Ichr797991668chr774163604343DRB1-0463GKNYEKAVNGEALGL217
BAIAP2L1-GTF2Ichr797991668chr774163604343DRB1-0464LGKNYEKAVNGEALG116
BAIAP2L1-GTF2Ichr797991668chr774163604343DRB1-0464GKNYEKAVNGEALGL217
BAIAP2L1-GTF2Ichr797991668chr774163604343DRB1-0469LGKNYEKAVNGEALG116
BAIAP2L1-GTF2Ichr797991668chr774163604343DRB1-0474LGKNYEKAVNGEALG116
BAIAP2L1-GTF2Ichr797991668chr774163604343DRB1-0474GKNYEKAVNGEALGL217
BAIAP2L1-GTF2Ichr797991668chr774163604343DRB1-0475LGKNYEKAVNGEALG116
BAIAP2L1-GTF2Ichr797991668chr774163604343DRB1-0475GKNYEKAVNGEALGL217
BAIAP2L1-GTF2Ichr797991668chr774163604343DRB1-0476LGKNYEKAVNGEALG116
BAIAP2L1-GTF2Ichr797991668chr774163604343DRB1-0476GKNYEKAVNGEALGL217
BAIAP2L1-GTF2Ichr797991668chr774163604343DRB1-0902LGKNYEKAVNGEALG116
BAIAP2L1-GTF2Ichr797991668chr774163604343DRB1-0902GKNYEKAVNGEALGL217
BAIAP2L1-GTF2Ichr797991668chr774163604343DRB5-0112LGKNYEKAVNGEALG116

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Fusion breakpoint peptide structures of BAIAP2L1-GTF2I

check button3D structures of the fusion breakpoint peptide of 14AA sequence that have potential fusion neoantigens
* The minimum length of the amino acid sequence in RoseTTAFold is 14AA. Here, we predicted the 14AA fusion protein breakpoint sequence not the fusion neoantigen peptide, which is shorter than 14 AA.
File nameBPseqHgeneTgeneHchrHbpTchrTbpAAlen
1824EKAVNGEALGLKQABAIAP2L1GTF2Ichr797991668chr774163604343

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Filtering FusionNeoAntigens Through Checking the Interaction with HLAs in 3D of BAIAP2L1-GTF2I

check buttonVirtual screening between 25 HLAs (from PDB) and FusionNeoAntigens
* We used Glide to predict the interaction between HLAs and neoantigens.
HLA allelePDB IDFile nameBPseqDocking scoreGlide score
HLA-B14:023BVN1824EKAVNGEALGLKQA-7.9962-8.1096
HLA-B14:023BVN1824EKAVNGEALGLKQA-5.70842-6.74372
HLA-B52:013W391824EKAVNGEALGLKQA-6.83737-6.95077
HLA-B52:013W391824EKAVNGEALGLKQA-4.4836-5.5189
HLA-A11:014UQ21824EKAVNGEALGLKQA-10.0067-10.1201
HLA-A11:014UQ21824EKAVNGEALGLKQA-9.03915-10.0745
HLA-A24:025HGA1824EKAVNGEALGLKQA-6.56204-6.67544
HLA-A24:025HGA1824EKAVNGEALGLKQA-5.42271-6.45801
HLA-B44:053DX81824EKAVNGEALGLKQA-7.85648-8.89178
HLA-B44:053DX81824EKAVNGEALGLKQA-5.3978-5.5112
HLA-A02:016TDR1824EKAVNGEALGLKQA-3.37154-4.40684

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Vaccine Design for the FusionNeoAntigens of BAIAP2L1-GTF2I

check button mRNA and peptide sequences of FusionNeoAntigens that have potential interaction with HLA-Is.
Fusion geneHchrHbpTchrTbpStart in +/-13AAEnd in +/-13AAFusionNeoAntigen peptide sequenceFusionNeoAntigen RNA sequence
BAIAP2L1-GTF2Ichr797991668chr7741636041020NGEALGLKQACTGTAAACGGGGAAGCTCTTGGCCTTAAAC
BAIAP2L1-GTF2Ichr797991668chr774163604514YEKAVNGEAAAAATTATGAGAAAGCTGTAAACGGGG
BAIAP2L1-GTF2Ichr797991668chr774163604515YEKAVNGEALAAAATTATGAGAAAGCTGTAAACGGGGAAG
BAIAP2L1-GTF2Ichr797991668chr774163604615EKAVNGEALATTATGAGAAAGCTGTAAACGGGGAAG
BAIAP2L1-GTF2Ichr797991668chr774163604818AVNGEALGLKAGAAAGCTGTAAACGGGGAAGCTCTTGGCC

check button mRNA and peptide sequences of FusionNeoAntigens that have potential interaction with HLA-IIs.
Fusion geneHchrHbpTchrTbpStart in +/-13AAEnd in +/-13AAFusionNeoAntigen peptideFusionNEoAntigen RNA sequence
BAIAP2L1-GTF2Ichr797991668chr774163604015NLGKNYEKAVNGEALTAATAAACCTGGGGAAAAATTATGAGAAAGCTGTAAACGGGGAAG
BAIAP2L1-GTF2Ichr797991668chr774163604116LGKNYEKAVNGEALGTAAACCTGGGGAAAAATTATGAGAAAGCTGTAAACGGGGAAGCTC
BAIAP2L1-GTF2Ichr797991668chr7741636041126GEALGLKQAVKVPFATAAACGGGGAAGCTCTTGGCCTTAAACAAGCTGTGAAGGTGCCGT
BAIAP2L1-GTF2Ichr797991668chr774163604217GKNYEKAVNGEALGLACCTGGGGAAAAATTATGAGAAAGCTGTAAACGGGGAAGCTCTTG

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Information of the samples that have these potential fusion neoantigens of BAIAP2L1-GTF2I

check button These samples were reported as having these fusion breakpoints. For individual breakpoints, we checked the open reading frames considering multiple gene isoforms and chose the in-frame fusion genes only. Then, we made fusion protein sequences and predicted the fusion neoantigens. These fusion-positive samples may have these potential fusion neoantigens.
Cancer typeFusion geneHchrHbpHenstTchrTbpTenstSample
STADBAIAP2L1-GTF2Ichr797991668ENST00000005260chr774163604ENST00000324896TCGA-VQ-A8E0

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Potential target of CAR-T therapy development for BAIAP2L1-GTF2I

check button Predicted 3D structure. We used RoseTTAFold.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, to provide the retention of the transmembrane domain, we only show the protein feature retention information of those transmembrane features


* Minus value of BPloci means that the break point is located before the CDS.
- In-frame and retained 'Transmembrane'.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

check button Subcellular localization prediction of the transmembrane domain retained fusion proteins
* We used DeepLoc 1.0. The order of the X-axis of the barplot is as follows: Entry_ID, Localization, Type, Nucleus, Cytoplasm, Extracellular, Mitochondrion, Cell_membrane, Endoplasmic_reticulum, Plastid, Golgi.apparatus, Lysosome.Vacuole, Peroxisome. Y-axis is the output score of DeepLoc. Clicking the image will open a new tab with a large image.
HgeneHchrHbpHenstTgeneTchrTbpTenstDeepLoc result

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Related Drugs to BAIAP2L1-GTF2I

check button Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDrugSourcePMID

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Related Diseases to BAIAP2L1-GTF2I

check button Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDiseaseSourcePMID

check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneBAIAP2L1C0003873Rheumatoid Arthritis1CTD_human