Home

Download

Statistics

Examples

Help

Contact

Fusion Protein:XRCC5-VWA3B

Fusion Gene and Fusion Protein Summary

Fusion gene summary

Fusion partner gene information	Fusion gene name: XRCC5-VWA3B
	FusionPDB ID: 99773
	FusionGDB2.0 ID: 99773
		Hgene	Tgene
	Gene symbol	XRCC5	VWA3B
	Gene ID	7520	200403
	Gene name	X-ray repair cross complementing 5	von Willebrand factor A domain containing 3B
	Synonyms	KARP-1\|KARP1\|KU80\|KUB2\|Ku86\|NFIV	SCAR22
	Cytomap	2q35	2q11.2
	Type of gene	protein-coding	protein-coding
	Description	X-ray repair cross-complementing protein 586 kDa subunit of Ku antigenATP-dependent DNA helicase 2 subunit 2ATP-dependent DNA helicase II 80 kDa subunitCTC box-binding factor 85 kDa subunitCTC85CTCBFDNA repair protein XRCC5Ku autoantigen, 80kDaKu	von Willebrand factor A domain-containing protein 3BVWA domain-containing protein 3B
	Modification date	20200313	20200313
	UniProtAcc	.	.
Ensembl transtripts involved in fusion gene	ENST ids	ENST00000392132, ENST00000392133, ENST00000471649,	ENST00000451075, ENST00000490947, ENST00000435344, ENST00000477737,
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)	* DoF score	13 X 10 X 7=910	6 X 9 X 6=324
	# samples	12	10
	** MAII score	log2(12/910*10)=-2.92283213947754 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(10/324*10)=-1.6959938131099 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Fusion gene context	PubMed: XRCC5 [Title/Abstract] AND VWA3B [Title/Abstract] AND fusion [Title/Abstract]
Fusion neoantigen context	PubMed: XRCC5 [Title/Abstract] AND VWA3B [Title/Abstract] AND neoantigen [Title/Abstract]
Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)	XRCC5(217026771)-VWA3B(98732114), # samples:1
Anticipated loss of major functional domain due to fusion event.	XRCC5-VWA3B seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. XRCC5-VWA3B seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. XRCC5-VWA3B seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. XRCC5-VWA3B seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Hgene	XRCC5	GO:0002218	activation of innate immune response	28712728
Hgene	XRCC5	GO:0006303	double-strand break repair via nonhomologous end joining	26359349
Hgene	XRCC5	GO:0045860	positive regulation of protein kinase activity	22504299
Hgene	XRCC5	GO:0071480	cellular response to gamma radiation	26359349

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr2:217026771/chr2:98732114)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Retention analysis results of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features, are available here.

Fusion gene breakpoints across XRCC5 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across VWA3B (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Top

Fusion Amino Acid Sequences

Fusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.

Henst

Tenst

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

Seq length
(transcript)

BP loci
(transcript)

Predicted start
(transcript)

Predicted stop
(transcript)

Seq length
(amino acids)

ENST00000392133

XRCC5

chr2

217026771

ENST00000435344

VWA3B

chr2

98732114

3974

2295

3973

1301

ENST00000392133

XRCC5

chr2

217026771

ENST00000477737

VWA3B

chr2

98732114

6349

2295

5983

1970

ENST00000392132

XRCC5

chr2

217026771

ENST00000435344

VWA3B

chr2

98732114

3653

1974

3652

1199

ENST00000392132

XRCC5

chr2

217026771

ENST00000477737

VWA3B

chr2

98732114

6028

1974

5662

1868

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000392133	ENST00000435344	XRCC5	chr2	217026771	+	VWA3B	chr2	98732114	+	0.001924504	0.9980755
ENST00000392133	ENST00000477737	XRCC5	chr2	217026771	+	VWA3B	chr2	98732114	+	0.001519035	0.998481
ENST00000392132	ENST00000435344	XRCC5	chr2	217026771	+	VWA3B	chr2	98732114	+	0.001653442	0.99834657
ENST00000392132	ENST00000477737	XRCC5	chr2	217026771	+	VWA3B	chr2	98732114	+	0.001354805	0.99864525

Predicted full-length fusion amino acid sequences. For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among all the predicted ones.

Get the fusion protein sequences from here.

Fusion protein sequence information is available in the fasta format.
>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

Top

Fusion Protein Breakpoint Sequences for XRCC5-VWA3B

+/-13 AA sequence from the breakpoints of the fusion protein sequences.

Hgene	Hchr	Hbp	Tgene	Tchr	Tbp	Length(fusion protein)	BP in fusion protein	Peptide
XRCC5	chr2	217026771	VWA3B	chr2	98732114	1974	639	RVLVKQKKASFEEDYVASLGRPVASR
XRCC5	chr2	217026771	VWA3B	chr2	98732114	2295	741	RVLVKQKKASFEEDYVASLGRPVASR

Top

Potential FusionNeoAntigen Information of XRCC5-VWA3B in HLA I

Multiple sequence alignments of the potential FusionNeoAntigens per fusion breakpoints. If the MSA is empty, then it means that there were predicted fusion neoantigens in this fusion breakpoint, but those predicted fusion neoantigens were not across the breakpoint, which is not fusion-specific.

XRCC5-VWA3B_217026771_98732114.msa

Potential FusionNeoAntigen Information
* We used NetMHCpan v4.1 (%rank<0.5) and deepHLApan v1.1 (immunogenic score>0.5)

Fusion gene	Hchr	Hbp	Tgene	Tchr	Tbp	HLA I	FusionNeoAntigen peptide	Binding score	Immunogenic score	Neoantigen start (at BP 13)	Neoantigen end (at BP 13)
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	HLA-B18:01	EEDYVASL	0.9892	0.9682	11	19
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	HLA-B13:01	FEEDYVASL	0.9956	0.9731	10	19
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	HLA-B47:01	FEEDYVASL	0.9794	0.7509	10	19
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	HLA-B18:01	FEEDYVASL	0.9722	0.9774	10	19
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	HLA-B39:13	FEEDYVASL	0.9578	0.9784	10	19
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	HLA-B39:01	FEEDYVASL	0.9544	0.9814	10	19
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	HLA-B38:02	FEEDYVASL	0.9537	0.9834	10	19
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	HLA-B15:10	FEEDYVASL	0.7747	0.8172	10	19
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	HLA-B15:37	FEEDYVASL	0.6752	0.8443	10	19
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	HLA-B50:01	FEEDYVASL	0.5414	0.7241	10	19
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	HLA-B41:01	FEEDYVASL	0.4795	0.9766	10	19
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	HLA-B15:03	KKASFEEDY	0.0251	0.7149	6	15
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	HLA-B15:01	KQKKASFEEDY	1	0.7623	4	15
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	HLA-B15:25	KQKKASFEEDY	0.9944	0.7853	4	15
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	HLA-B39:08	EEDYVASL	0.9829	0.7943	11	19
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	HLA-B40:06	FEEDYVASL	0.9995	0.6786	10	19
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	HLA-B40:03	FEEDYVASL	0.9689	0.537	10	19
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	HLA-B39:09	FEEDYVASL	0.9673	0.7693	10	19
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	HLA-B39:05	FEEDYVASL	0.9571	0.9769	10	19
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	HLA-B39:12	FEEDYVASL	0.9279	0.9832	10	19
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	HLA-B39:08	FEEDYVASL	0.8047	0.9261	10	19
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	HLA-C04:10	SFEEDYVASL	0.9995	0.8937	9	19
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	HLA-B39:08	SFEEDYVASL	0.9379	0.8729	9	19
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	HLA-B15:07	KQKKASFEEDY	0.9999	0.5182	4	15
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	HLA-B39:08	ASFEEDYVASL	0.996	0.9171	8	19
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	HLA-B18:05	EEDYVASL	0.9892	0.9682	11	19
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	HLA-B18:06	EEDYVASL	0.9863	0.9723	11	19
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	HLA-B18:08	EEDYVASL	0.9848	0.9329	11	19
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	HLA-B18:03	EEDYVASL	0.9833	0.9651	11	19
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	HLA-B39:11	EEDYVASL	0.9808	0.7556	11	19
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	HLA-B18:11	EEDYVASL	0.9537	0.9482	11	19
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	HLA-B40:04	FEEDYVASL	0.9992	0.7703	10	19
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	HLA-C18:01	FEEDYVASL	0.9967	0.8322	10	19
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	HLA-B18:04	FEEDYVASL	0.9831	0.9821	10	19
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	HLA-B18:07	FEEDYVASL	0.9769	0.9543	10	19
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	HLA-B18:05	FEEDYVASL	0.9722	0.9774	10	19
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	HLA-B18:08	FEEDYVASL	0.9676	0.9646	10	19
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	HLA-B18:03	FEEDYVASL	0.9674	0.9752	10	19
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	HLA-B18:06	FEEDYVASL	0.9647	0.981	10	19
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	HLA-B39:31	FEEDYVASL	0.9599	0.9813	10	19
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	HLA-B39:02	FEEDYVASL	0.9559	0.9802	10	19
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	HLA-B18:11	FEEDYVASL	0.9199	0.9692	10	19
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	HLA-B39:11	FEEDYVASL	0.8012	0.9124	10	19
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	HLA-B15:09	FEEDYVASL	0.7577	0.6671	10	19
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	HLA-B41:03	FEEDYVASL	0.6659	0.7523	10	19
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	HLA-B50:04	FEEDYVASL	0.5414	0.7241	10	19
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	HLA-B50:05	FEEDYVASL	0.5414	0.7241	10	19
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	HLA-B48:02	KKASFEEDY	0.0395	0.8986	6	15
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	HLA-B15:54	KKASFEEDY	0.0037	0.8867	6	15
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	HLA-B40:04	SFEEDYVASL	0.805	0.7739	9	19
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	HLA-B41:03	SFEEDYVASL	0.6967	0.639	9	19
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	HLA-B15:27	KQKKASFEEDY	1	0.7729	4	15
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	HLA-B15:34	KQKKASFEEDY	1	0.7623	4	15
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	HLA-B15:135	KQKKASFEEDY	1	0.7788	4	15
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	HLA-B15:125	KQKKASFEEDY	1	0.7623	4	15
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	HLA-B15:33	KQKKASFEEDY	1	0.7623	4	15
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	HLA-B15:50	KQKKASFEEDY	0.9999	0.7414	4	15
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	HLA-B15:35	KQKKASFEEDY	0.9998	0.7275	4	15
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	HLA-B15:53	KQKKASFEEDY	0.9991	0.7182	4	15
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	HLA-B15:54	KQKKASFEEDY	0.9965	0.6912	4	15
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	HLA-B41:03	ASFEEDYVASL	0.9786	0.6381	8	19

Top

Potential FusionNeoAntigen Information of XRCC5-VWA3B in HLA II

XRCC5-VWA3B_217026771_98732114.msa

Potential FusionNeoAntigen Information
* We used NetMHCIIpan v4.1 (%rank<0.5).

Fusion gene	Hchr	Hbp	Tgene	Tchr	Tbp	HLA II	FusionNeoAntigen peptide	Neoantigen start (at BP 13)	Neoantigen end (at BP 13)
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0101	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0101	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0101	SFEEDYVASLGRPVA	9	24
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0103	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0103	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0103	SFEEDYVASLGRPVA	9	24
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0105	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0105	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0105	SFEEDYVASLGRPVA	9	24
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0107	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0107	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0107	SFEEDYVASLGRPVA	9	24
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0109	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0109	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0109	SFEEDYVASLGRPVA	9	24
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0111	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0111	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0111	SFEEDYVASLGRPVA	9	24
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0113	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0113	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0113	SFEEDYVASLGRPVA	9	24
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0115	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0115	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0115	SFEEDYVASLGRPVA	9	24
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0117	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0117	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0117	SFEEDYVASLGRPVA	9	24
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0119	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0119	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0119	SFEEDYVASLGRPVA	9	24
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0121	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0121	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0121	SFEEDYVASLGRPVA	9	24
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0125	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0125	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0125	SFEEDYVASLGRPVA	9	24
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0127	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0127	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0127	SFEEDYVASLGRPVA	9	24
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0129	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0129	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0129	SFEEDYVASLGRPVA	9	24
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0131	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0131	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0131	SFEEDYVASLGRPVA	9	24
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0338	KASFEEDYVASLGRP	7	22
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0469	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0701	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0701	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0701	SFEEDYVASLGRPVA	9	24
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0701	ASFEEDYVASLGRPV	8	23
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0703	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0703	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0703	SFEEDYVASLGRPVA	9	24
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0703	ASFEEDYVASLGRPV	8	23
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0704	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0704	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0704	SFEEDYVASLGRPVA	9	24
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0704	ASFEEDYVASLGRPV	8	23
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0705	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0705	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0705	SFEEDYVASLGRPVA	9	24
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0705	ASFEEDYVASLGRPV	8	23
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0706	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0706	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0706	SFEEDYVASLGRPVA	9	24
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0706	ASFEEDYVASLGRPV	8	23
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0707	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0707	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0707	SFEEDYVASLGRPVA	9	24
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0707	ASFEEDYVASLGRPV	8	23
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0708	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0708	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0708	SFEEDYVASLGRPVA	9	24
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0708	ASFEEDYVASLGRPV	8	23
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0709	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0709	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0709	SFEEDYVASLGRPVA	9	24
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0709	ASFEEDYVASLGRPV	8	23
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0711	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0711	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0711	SFEEDYVASLGRPVA	9	24
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0711	ASFEEDYVASLGRPV	8	23
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0712	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0712	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0712	SFEEDYVASLGRPVA	9	24
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0712	ASFEEDYVASLGRPV	8	23
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0713	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0713	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0713	SFEEDYVASLGRPVA	9	24
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0713	ASFEEDYVASLGRPV	8	23
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0714	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0714	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0714	SFEEDYVASLGRPVA	9	24
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0714	ASFEEDYVASLGRPV	8	23
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0715	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0715	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0715	SFEEDYVASLGRPVA	9	24
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0715	ASFEEDYVASLGRPV	8	23
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0716	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0716	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0716	SFEEDYVASLGRPVA	9	24
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0716	ASFEEDYVASLGRPV	8	23
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0717	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0717	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0717	SFEEDYVASLGRPVA	9	24
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0717	ASFEEDYVASLGRPV	8	23
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0719	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0719	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0719	SFEEDYVASLGRPVA	9	24
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0719	ASFEEDYVASLGRPV	8	23
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0802	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0804	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0804	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0807	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0807	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0808	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0809	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0811	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0813	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0815	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0819	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0819	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0819	SFEEDYVASLGRPVA	9	24
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0820	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0821	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0824	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0825	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0825	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0828	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0830	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0831	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0831	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0834	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0834	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0834	SFEEDYVASLGRPVA	9	24
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0901	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0901	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0901	SFEEDYVASLGRPVA	9	24
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0901	ASFEEDYVASLGRPV	8	23
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0902	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0902	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0902	SFEEDYVASLGRPVA	9	24
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0903	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0903	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0903	SFEEDYVASLGRPVA	9	24
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0903	ASFEEDYVASLGRPV	8	23
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0904	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0904	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0904	SFEEDYVASLGRPVA	9	24
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0904	ASFEEDYVASLGRPV	8	23
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0905	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0905	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0905	SFEEDYVASLGRPVA	9	24
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0905	ASFEEDYVASLGRPV	8	23
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0907	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0907	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0907	SFEEDYVASLGRPVA	9	24
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0907	ASFEEDYVASLGRPV	8	23
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0908	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0908	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0908	SFEEDYVASLGRPVA	9	24
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0909	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0909	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0909	SFEEDYVASLGRPVA	9	24
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-0909	ASFEEDYVASLGRPV	8	23
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1101	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1104	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1105	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1106	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1109	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1110	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1112	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1114	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1115	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1118	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1120	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1124	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1125	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1128	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1129	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1130	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1133	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1134	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1135	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1138	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1139	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1142	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1143	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1144	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1145	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1146	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1147	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1149	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1150	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1151	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1154	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1156	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1157	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1158	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1160	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1161	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1162	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1164	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1166	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1167	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1172	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1174	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1175	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1177	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1178	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1183	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1184	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1188	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1190	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1191	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1192	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1194	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1195	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1196	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1204	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1209	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1216	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1222	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1302	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1305	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1306	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-13100	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-13100	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1311	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1314	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1318	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1323	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1331	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1331	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1334	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1336	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1339	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1341	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1342	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1343	RVLVKQKKASFEEDY	0	15
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1344	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1346	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1346	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1350	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1354	RVLVKQKKASFEEDY	0	15
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1362	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1367	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1367	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1373	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1374	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1386	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1396	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1397	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1399	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1402	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1403	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1406	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1407	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1412	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1414	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1415	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1415	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1416	RVLVKQKKASFEEDY	0	15
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1417	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1420	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1424	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1429	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1434	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1436	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1440	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1441	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1442	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1444	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1446	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1447	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1448	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1448	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1449	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1451	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1463	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1467	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1468	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1468	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1473	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1477	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1480	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1483	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1484	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1489	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1493	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1493	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1493	SFEEDYVASLGRPVA	9	24
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1494	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1498	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1502	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1502	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1508	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1508	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1511	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1511	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1514	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1514	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1515	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1515	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1519	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1519	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1526	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1526	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1527	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1527	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1529	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1529	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1529	SFEEDYVASLGRPVA	9	24
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1530	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1530	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1531	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1531	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1534	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1534	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1534	SFEEDYVASLGRPVA	9	24
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1538	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1538	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1539	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1539	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1544	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1544	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1547	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1547	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1601	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1601	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1601	SFEEDYVASLGRPVA	9	24
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1602	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1602	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1602	SFEEDYVASLGRPVA	9	24
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1603	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1603	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1603	SFEEDYVASLGRPVA	9	24
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1604	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1604	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1604	SFEEDYVASLGRPVA	9	24
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1605	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1605	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1605	SFEEDYVASLGRPVA	9	24
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1607	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1607	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1607	SFEEDYVASLGRPVA	9	24
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1608	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1608	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1608	SFEEDYVASLGRPVA	9	24
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1609	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1609	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1609	SFEEDYVASLGRPVA	9	24
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1610	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1610	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1610	SFEEDYVASLGRPVA	9	24
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1611	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1611	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1611	SFEEDYVASLGRPVA	9	24
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1612	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1612	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1612	SFEEDYVASLGRPVA	9	24
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1614	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1614	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1614	SFEEDYVASLGRPVA	9	24
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1616	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1616	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB1-1616	SFEEDYVASLGRPVA	9	24
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB3-0101	KASFEEDYVASLGRP	7	22
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB3-0101	KKASFEEDYVASLGR	6	21
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB3-0104	KASFEEDYVASLGRP	7	22
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB3-0104	KKASFEEDYVASLGR	6	21
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB3-0105	KASFEEDYVASLGRP	7	22
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB3-0105	KKASFEEDYVASLGR	6	21
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB3-0108	KASFEEDYVASLGRP	7	22
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB3-0108	KKASFEEDYVASLGR	6	21
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB3-0109	KASFEEDYVASLGRP	7	22
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB3-0109	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB3-0111	KASFEEDYVASLGRP	7	22
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB3-0111	KKASFEEDYVASLGR	6	21
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB3-0112	KASFEEDYVASLGRP	7	22
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB3-0112	KKASFEEDYVASLGR	6	21
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB3-0113	KASFEEDYVASLGRP	7	22
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB3-0113	KKASFEEDYVASLGR	6	21
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB3-0114	KASFEEDYVASLGRP	7	22
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB3-0114	KKASFEEDYVASLGR	6	21
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB3-0202	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB3-0205	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB3-0205	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB3-0209	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB3-0209	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB3-0209	SFEEDYVASLGRPVA	9	24
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB3-0210	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB3-0211	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB3-0212	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB3-0212	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB3-0213	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB3-0215	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB3-0215	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB3-0216	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB3-0216	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB3-0217	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB3-0217	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB3-0218	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB3-0219	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB3-0220	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB3-0221	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB3-0221	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB3-0221	SFEEDYVASLGRPVA	9	24
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB3-0222	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB3-0223	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB3-0225	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB3-0303	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB3-0303	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB3-0303	KASFEEDYVASLGRP	7	22
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB3-0303	SFEEDYVASLGRPVA	9	24
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB5-0102	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB5-0103	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB5-0104	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB5-0108N	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB5-0111	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB5-0112	EEDYVASLGRPVASR	11	26
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB5-0112	FEEDYVASLGRPVAS	10	25
XRCC5-VWA3B	chr2	217026771	chr2	98732114	1974	DRB5-0112	SFEEDYVASLGRPVA	9	24

Top

Fusion breakpoint peptide structures of XRCC5-VWA3B

3D structures of the fusion breakpoint peptide of 14AA sequence that have potential fusion neoantigens
* The minimum length of the amino acid sequence in RoseTTAFold is 14AA. Here, we predicted the 14AA fusion protein breakpoint sequence not the fusion neoantigen peptide, which is shorter than 14 AA.

File name	BPseq	Hgene	Tgene	Hchr	Hbp	Tchr	Tbp	AAlen
4323	KKASFEEDYVASLG	XRCC5	VWA3B	chr2	217026771	chr2	98732114	1974

Top

Filtering FusionNeoAntigens Through Checking the Interaction with HLAs in 3D of XRCC5-VWA3B

Virtual screening between 25 HLAs (from PDB) and FusionNeoAntigens
* We used Glide to predict the interaction between HLAs and neoantigens.

HLA allele	PDB ID	File name	BPseq	Docking score	Glide score
HLA-B14:02	3BVN	4323	KKASFEEDYVASLG	-7.15543	-7.26883
HLA-B14:02	3BVN	4323	KKASFEEDYVASLG	-4.77435	-5.80965
HLA-B52:01	3W39	4323	KKASFEEDYVASLG	-6.80875	-6.92215
HLA-B52:01	3W39	4323	KKASFEEDYVASLG	-4.20386	-5.23916
HLA-A11:01	4UQ2	4323	KKASFEEDYVASLG	-7.5194	-8.5547
HLA-A11:01	4UQ2	4323	KKASFEEDYVASLG	-6.9601	-7.0735
HLA-A24:02	5HGA	4323	KKASFEEDYVASLG	-7.52403	-7.63743
HLA-A24:02	5HGA	4323	KKASFEEDYVASLG	-5.82433	-6.85963
HLA-B27:05	6PYJ	4323	KKASFEEDYVASLG	-3.28285	-4.31815
HLA-B44:05	3DX8	4323	KKASFEEDYVASLG	-5.91172	-6.94702
HLA-B44:05	3DX8	4323	KKASFEEDYVASLG	-4.24346	-4.35686

Top

Vaccine Design for the FusionNeoAntigens of XRCC5-VWA3B

mRNA and peptide sequences of FusionNeoAntigens that have potential interaction with HLA-Is.

Fusion gene	Hchr	Hbp	Tchr	Tbp	Start in +/-13AA	End in +/-13AA	FusionNeoAntigen peptide sequence	FusionNeoAntigen RNA sequence
XRCC5-VWA3B	chr2	217026771	chr2	98732114	10	19	FEEDYVASL	TTGAGGAAGATTATGTGGCGTCTCTGG
XRCC5-VWA3B	chr2	217026771	chr2	98732114	11	19	EEDYVASL	AGGAAGATTATGTGGCGTCTCTGG
XRCC5-VWA3B	chr2	217026771	chr2	98732114	4	15	KQKKASFEEDY	AACAGAAGAAGGCCAGCTTTGAGGAAGATTATG
XRCC5-VWA3B	chr2	217026771	chr2	98732114	6	15	KKASFEEDY	AGAAGGCCAGCTTTGAGGAAGATTATG
XRCC5-VWA3B	chr2	217026771	chr2	98732114	8	19	ASFEEDYVASL	CCAGCTTTGAGGAAGATTATGTGGCGTCTCTGG
XRCC5-VWA3B	chr2	217026771	chr2	98732114	9	19	SFEEDYVASL	GCTTTGAGGAAGATTATGTGGCGTCTCTGG

mRNA and peptide sequences of FusionNeoAntigens that have potential interaction with HLA-IIs.

Fusion gene	Hchr	Hbp	Tchr	Tbp	Start in +/-13AA	End in +/-13AA	FusionNeoAntigen peptide	FusionNEoAntigen RNA sequence
XRCC5-VWA3B	chr2	217026771	chr2	98732114	0	15	RVLVKQKKASFEEDY	GTGTTCTAGTGAAACAGAAGAAGGCCAGCTTTGAGGAAGATTATG
XRCC5-VWA3B	chr2	217026771	chr2	98732114	10	25	FEEDYVASLGRPVAS	TTGAGGAAGATTATGTGGCGTCTCTGGGGAGACCTGTGGCTTCTC
XRCC5-VWA3B	chr2	217026771	chr2	98732114	11	26	EEDYVASLGRPVASR	AGGAAGATTATGTGGCGTCTCTGGGGAGACCTGTGGCTTCTCGGT
XRCC5-VWA3B	chr2	217026771	chr2	98732114	6	21	KKASFEEDYVASLGR	AGAAGGCCAGCTTTGAGGAAGATTATGTGGCGTCTCTGGGGAGAC
XRCC5-VWA3B	chr2	217026771	chr2	98732114	7	22	KASFEEDYVASLGRP	AGGCCAGCTTTGAGGAAGATTATGTGGCGTCTCTGGGGAGACCTG
XRCC5-VWA3B	chr2	217026771	chr2	98732114	8	23	ASFEEDYVASLGRPV	CCAGCTTTGAGGAAGATTATGTGGCGTCTCTGGGGAGACCTGTGG
XRCC5-VWA3B	chr2	217026771	chr2	98732114	9	24	SFEEDYVASLGRPVA	GCTTTGAGGAAGATTATGTGGCGTCTCTGGGGAGACCTGTGGCTT

Top

Information of the samples that have these potential fusion neoantigens of XRCC5-VWA3B

These samples were reported as having these fusion breakpoints. For individual breakpoints, we checked the open reading frames considering multiple gene isoforms and chose the in-frame fusion genes only. Then, we made fusion protein sequences and predicted the fusion neoantigens. These fusion-positive samples may have these potential fusion neoantigens.

Cancer type	Fusion gene	Hchr	Hbp	Henst	Tchr	Tbp	Tenst	Sample
OV	XRCC5-VWA3B	chr2	217026771	ENST00000392132	chr2	98732114	ENST00000435344	TCGA-25-2392

Top

Potential target of CAR-T therapy development for XRCC5-VWA3B

Predicted 3D structure. We used RoseTTAFold.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, to provide the retention of the transmembrane domain, we only show the protein feature retention information of those transmembrane features

* Minus value of BPloci means that the break point is located before the CDS.

- In-frame and retained 'Transmembrane'.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Subcellular localization prediction of the transmembrane domain retained fusion proteins
* We used DeepLoc 1.0. The order of the X-axis of the barplot is as follows: Entry_ID, Localization, Type, Nucleus, Cytoplasm, Extracellular, Mitochondrion, Cell_membrane, Endoplasmic_reticulum, Plastid, Golgi.apparatus, Lysosome.Vacuole, Peroxisome. Y-axis is the output score of DeepLoc. Clicking the image will open a new tab with a large image.

Hgene

Hchr

Hbp

Henst

Tgene

Tchr

Tbp

Tenst

DeepLoc result

Top

Related Drugs to XRCC5-VWA3B

Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)

Hgene

Tgene

Drug

Source

PMID

Top

Related Diseases to XRCC5-VWA3B

Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)

Hgene

Tgene

Disease

Source

PMID

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source

	Fusion Gene and Fusion Protein Summary
	Fusion Amino Acid Sequences (multiple BPs and multiple gene isoforms)
	Fusion Protein Breakpoint Sequences - (for the Screening of the FusionNeoAntigens)
	Potential FusionNeoAntigens in HLA I - (netMHCpan v4.1 + deepHLApan v1.1)
	Potential FusionNeoAntigens in HLA II - (netMHCIIpan v4.1)
	Fusion Breakpoint 14 AA Peptide Structure - (RoseTTAFold)
	Filtering FusionNeoAntigens Through Checking the Interaction with HLAs in 3D - (Glide)
	Vaccine Design for the FusionNeoAntigens (RNA/protein sequences)
	Potential target of CAR-T therapy development
	Information on the samples that have these potential fusion neoantigens
	Fusion Protein Targeting Drugs - (Manual Curation)
	Fusion Protein Related diseases - (Manual Curation)