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Center for Computational Systems Medicine level1
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Fusion Gene Summary

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Fusion Gene Sample Information

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Fusion ORF Analysis

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Fusion Amino Acid Sequences

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Fusion Protein Functional Features

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Fusion Protein-Protein Interaction

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Related drugs with this fusion protein

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Related disease with this fusion protein

Fusion Protein:BPTF-RGS9

Fusion Protein Summary

check button Fusion gene summary
Fusion partner gene informationFusion gene name: BPTF-RGS9
FusionPDB ID: 10101
FusionGDB2.0 ID: 10101
HgeneTgene
Gene symbol

BPTF

RGS9

Gene ID

2186

388531

Gene namebromodomain PHD finger transcription factorregulator of G protein signaling 9 binding protein
SynonymsFAC1|FALZ|NEDDFL|NURF301PERRS|R9AP|RGS9
Cytomap

17q24.2

19q13.11

Type of geneprotein-codingprotein-coding
Descriptionnucleosome-remodeling factor subunit BPTFbromodomain and PHD domain transcription factorbromodomain and PHD finger-containing transcription factorfetal Alz-50 clone 1 proteinfetal Alz-50 reactive clone 1fetal Alzheimer antigennucleosome remodeling fregulator of G-protein signaling 9-binding proteinRGS9 anchor proteinRGS9-anchoring protein
Modification date2020031320200313
UniProtAcc

Q12830

.
Ensembl transtripts involved in fusion geneENST idsENST00000306378, ENST00000321892, 
ENST00000335221, ENST00000424123, 
ENST00000577770, 		ENST00000577186, 
ENST00000262406, ENST00000443584, 
ENST00000449996, 
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)* DoF score27 X 21 X 13=737113 X 16 X 5=1040
# samples 4215
** MAII scorelog2(42/7371*10)=-4.1333991254172
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(15/1040*10)=-2.79354912253257
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context (manual curation of fusion genes in FusionPDB)

PubMed: BPTF [Title/Abstract] AND RGS9 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)BPTF(65850878)-RGS9(63164318), # samples:2
Anticipated loss of major functional domain due to fusion event.BPTF-RGS9 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
BPTF-RGS9 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
BPTF-RGS9 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
BPTF-RGS9 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
BPTF-RGS9 seems lost the major protein functional domain in Hgene partner, which is a epigenetic factor due to the frame-shifted ORF.
BPTF-RGS9 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
BPTF-RGS9 seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
BPTF-RGS9 seems lost the major protein functional domain in Hgene partner, which is a transcription factor due to the frame-shifted ORF.
BPTF-RGS9 seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneBPTF

GO:0000122

negative regulation of transcription by RNA polymerase II

10727212

HgeneBPTF

GO:0006338

chromatin remodeling

14609955


check buttonFusion gene breakpoints across BPTF (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across RGS9 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure


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Fusion Gene Sample Information

check buttonFusion gene information from FusionGDB2.0.
check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-E9-A22D-01ABPTFchr17

65850877

+RGS9chr17

63164317

+
ChimerDB4BRCATCGA-E9-A22D-01ABPTFchr17

65850877

+RGS9chr17

63173849

+
ChimerDB4BRCATCGA-E9-A22D-01ABPTFchr17

65850878

-RGS9chr17

63164318

+
ChimerDB4BRCATCGA-E9-A22D-01ABPTFchr17

65850878

+RGS9chr17

63164318

+
ChimerDB4BRCATCGA-E9-A22DBPTFchr17

65850878

+RGS9chr17

63164317

+
ChimerDB4BRCATCGA-E9-A22DBPTFchr17

65850878

+RGS9chr17

63173849

+


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Fusion ORF Analysis


check buttonFusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000335221BPTFchr1765850878+ENST00000443584RGS9chr1763164318+29821497612883940
ENST00000335221BPTFchr1765850878+ENST00000449996RGS9chr1763164318+33091497613012983
ENST00000335221BPTFchr1765850878+ENST00000262406RGS9chr1763164318+33051497613021986
ENST00000321892BPTFchr1765850878+ENST00000443584RGS9chr1763164318+29821497612883940
ENST00000321892BPTFchr1765850878+ENST00000449996RGS9chr1763164318+33091497613012983
ENST00000321892BPTFchr1765850878+ENST00000262406RGS9chr1763164318+33051497613021986
ENST00000306378BPTFchr1765850878+ENST00000443584RGS9chr1763164318+29811496602882940
ENST00000306378BPTFchr1765850878+ENST00000449996RGS9chr1763164318+33081496603011983
ENST00000306378BPTFchr1765850878+ENST00000262406RGS9chr1763164318+33041496603020986
ENST00000424123BPTFchr1765850878+ENST00000443584RGS9chr1763164318+2504101902405801
ENST00000424123BPTFchr1765850878+ENST00000449996RGS9chr1763164318+2831101902534844
ENST00000424123BPTFchr1765850878+ENST00000262406RGS9chr1763164318+2827101902543847
ENST00000335221BPTFchr1765850878+ENST00000443584RGS9chr1763164317+29821497612883940
ENST00000335221BPTFchr1765850878+ENST00000449996RGS9chr1763164317+33091497613012983
ENST00000335221BPTFchr1765850878+ENST00000262406RGS9chr1763164317+33051497613021986
ENST00000321892BPTFchr1765850878+ENST00000443584RGS9chr1763164317+29821497612883940
ENST00000321892BPTFchr1765850878+ENST00000449996RGS9chr1763164317+33091497613012983
ENST00000321892BPTFchr1765850878+ENST00000262406RGS9chr1763164317+33051497613021986
ENST00000306378BPTFchr1765850878+ENST00000443584RGS9chr1763164317+29811496602882940
ENST00000306378BPTFchr1765850878+ENST00000449996RGS9chr1763164317+33081496603011983
ENST00000306378BPTFchr1765850878+ENST00000262406RGS9chr1763164317+33041496603020986
ENST00000424123BPTFchr1765850878+ENST00000443584RGS9chr1763164317+2504101902405801
ENST00000424123BPTFchr1765850878+ENST00000449996RGS9chr1763164317+2831101902534844
ENST00000424123BPTFchr1765850878+ENST00000262406RGS9chr1763164317+2827101902543847
ENST00000335221BPTFchr1765850877+ENST00000443584RGS9chr1763164317+29821497612883940
ENST00000335221BPTFchr1765850877+ENST00000449996RGS9chr1763164317+33091497613012983
ENST00000335221BPTFchr1765850877+ENST00000262406RGS9chr1763164317+33051497613021986
ENST00000321892BPTFchr1765850877+ENST00000443584RGS9chr1763164317+29821497612883940
ENST00000321892BPTFchr1765850877+ENST00000449996RGS9chr1763164317+33091497613012983
ENST00000321892BPTFchr1765850877+ENST00000262406RGS9chr1763164317+33051497613021986
ENST00000306378BPTFchr1765850877+ENST00000443584RGS9chr1763164317+29811496602882940
ENST00000306378BPTFchr1765850877+ENST00000449996RGS9chr1763164317+33081496603011983
ENST00000306378BPTFchr1765850877+ENST00000262406RGS9chr1763164317+33041496603020986
ENST00000424123BPTFchr1765850877+ENST00000443584RGS9chr1763164317+2504101902405801
ENST00000424123BPTFchr1765850877+ENST00000449996RGS9chr1763164317+2831101902534844
ENST00000424123BPTFchr1765850877+ENST00000262406RGS9chr1763164317+2827101902543847

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000335221ENST00000443584BPTFchr1765850878+RGS9chr1763164318+0.0051224550.9948775
ENST00000335221ENST00000449996BPTFchr1765850878+RGS9chr1763164318+0.003079050.99692094
ENST00000335221ENST00000262406BPTFchr1765850878+RGS9chr1763164318+0.003070690.99692935
ENST00000321892ENST00000443584BPTFchr1765850878+RGS9chr1763164318+0.0051224550.9948775
ENST00000321892ENST00000449996BPTFchr1765850878+RGS9chr1763164318+0.003079050.99692094
ENST00000321892ENST00000262406BPTFchr1765850878+RGS9chr1763164318+0.003070690.99692935
ENST00000306378ENST00000443584BPTFchr1765850878+RGS9chr1763164318+0.005121280.99487865
ENST00000306378ENST00000449996BPTFchr1765850878+RGS9chr1763164318+0.0030768530.99692315
ENST00000306378ENST00000262406BPTFchr1765850878+RGS9chr1763164318+0.0030685120.99693143
ENST00000424123ENST00000443584BPTFchr1765850878+RGS9chr1763164318+0.0035743770.99642557
ENST00000424123ENST00000449996BPTFchr1765850878+RGS9chr1763164318+0.0025812790.99741876
ENST00000424123ENST00000262406BPTFchr1765850878+RGS9chr1763164318+0.0025926750.9974074
ENST00000335221ENST00000443584BPTFchr1765850878+RGS9chr1763164317+0.0051224550.9948775
ENST00000335221ENST00000449996BPTFchr1765850878+RGS9chr1763164317+0.003079050.99692094
ENST00000335221ENST00000262406BPTFchr1765850878+RGS9chr1763164317+0.003070690.99692935
ENST00000321892ENST00000443584BPTFchr1765850878+RGS9chr1763164317+0.0051224550.9948775
ENST00000321892ENST00000449996BPTFchr1765850878+RGS9chr1763164317+0.003079050.99692094
ENST00000321892ENST00000262406BPTFchr1765850878+RGS9chr1763164317+0.003070690.99692935
ENST00000306378ENST00000443584BPTFchr1765850878+RGS9chr1763164317+0.005121280.99487865
ENST00000306378ENST00000449996BPTFchr1765850878+RGS9chr1763164317+0.0030768530.99692315
ENST00000306378ENST00000262406BPTFchr1765850878+RGS9chr1763164317+0.0030685120.99693143
ENST00000424123ENST00000443584BPTFchr1765850878+RGS9chr1763164317+0.0035743770.99642557
ENST00000424123ENST00000449996BPTFchr1765850878+RGS9chr1763164317+0.0025812790.99741876
ENST00000424123ENST00000262406BPTFchr1765850878+RGS9chr1763164317+0.0025926750.9974074
ENST00000335221ENST00000443584BPTFchr1765850877+RGS9chr1763164317+0.0051224550.9948775
ENST00000335221ENST00000449996BPTFchr1765850877+RGS9chr1763164317+0.003079050.99692094
ENST00000335221ENST00000262406BPTFchr1765850877+RGS9chr1763164317+0.003070690.99692935
ENST00000321892ENST00000443584BPTFchr1765850877+RGS9chr1763164317+0.0051224550.9948775
ENST00000321892ENST00000449996BPTFchr1765850877+RGS9chr1763164317+0.003079050.99692094
ENST00000321892ENST00000262406BPTFchr1765850877+RGS9chr1763164317+0.003070690.99692935
ENST00000306378ENST00000443584BPTFchr1765850877+RGS9chr1763164317+0.005121280.99487865
ENST00000306378ENST00000449996BPTFchr1765850877+RGS9chr1763164317+0.0030768530.99692315
ENST00000306378ENST00000262406BPTFchr1765850877+RGS9chr1763164317+0.0030685120.99693143
ENST00000424123ENST00000443584BPTFchr1765850877+RGS9chr1763164317+0.0035743770.99642557
ENST00000424123ENST00000449996BPTFchr1765850877+RGS9chr1763164317+0.0025812790.99741876
ENST00000424123ENST00000262406BPTFchr1765850877+RGS9chr1763164317+0.0025926750.9974074

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Fusion Amino Acid Sequences


check button For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

>10101_10101_1_BPTF-RGS9_BPTF_chr17_65850877_ENST00000306378_RGS9_chr17_63164317_ENST00000262406_length(amino acids)=986AA_BP=6
MRGRRGRPPKQPAAPAAERCAPAPPPPPPPPTSGPIGGLRSRHRGSSRGRWAAAQAEVAPKTRLSSPRGGSSSRRKPPPPPPAPPSTSAP
GRGGRGGGGGRTGGGGGGGHLARTTAARRAVNKVVYDDHESEEEEEEEDMVSEEEEEEDGDAEETQDSEDDEEDEMEEDDDDSDYPEEME
DDDDDASYCTESSFRSHSTYSSTPGRRKPRVHRPRSPILEEKDIPPLEFPKSSEDLMVPNEHIMNVIAIYEVLRNFGTVLRLSPFRFEDF
CAALVSQEQCTLMAEMHVVLLKAVLREEDTSNTTFGPADLKDSVNSTLYFIDGMTWPEVLRVYCESDKEYHHVLPYQEAEDYPYGPVENK
IKVLQFLVDQFLTTNIAREELMSEGVIQYDDHCRVCHKLGDLLCCETCSAVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVTDCVAEIQ
KNKPYIRHEPIGYDRSRRKYWFLNRRLIMAGKERNKADRYALDCQEKAYWLVHRCPPGMDNVLDYGLDRVTNPNEVKVNQKQTVVAVKKE
IMYYQQALMRSTVKSSVSLGGIVKYSEQFSSNDAIMSGCLPSNPWITDDTQFWDLNAKLVEIPTKMRVERWAFNFSELIRDPKGRQSFQY
FLKKEFSGENLGFWEACEDLKYGDQSKVKEKAEEIYKLFLAPGARRWINIDGKTMDITVKGLKHPHRYVLDAAQTHIYMLMKKDSYARYL
KSPIYKDMLAKAIEPQETTKKSSTLPFMRRHLRSSPSPVILRQLEEEAKAREAANTVDITQPGQHMAPSPHLTVYTGTCMPPSPSSPFSS
SCRSPRKPFASPSRFIRRPSTTICPSPIRVALESSSGLEQKGECSGSMAPRGPSVTESSEASLDTSWPRSRPRAPPKARMALSFSRFLRR

--------------------------------------------------------------

>10101_10101_2_BPTF-RGS9_BPTF_chr17_65850877_ENST00000306378_RGS9_chr17_63164317_ENST00000443584_length(amino acids)=940AA_BP=6
MRGRRGRPPKQPAAPAAERCAPAPPPPPPPPTSGPIGGLRSRHRGSSRGRWAAAQAEVAPKTRLSSPRGGSSSRRKPPPPPPAPPSTSAP
GRGGRGGGGGRTGGGGGGGHLARTTAARRAVNKVVYDDHESEEEEEEEDMVSEEEEEEDGDAEETQDSEDDEEDEMEEDDDDSDYPEEME
DDDDDASYCTESSFRSHSTYSSTPGRRKPRVHRPRSPILEEKDIPPLEFPKSSEDLMVPNEHIMNVIAIYEVLRNFGTVLRLSPFRFEDF
CAALVSQEQCTLMAEMHVVLLKAVLREEDTSNTTFGPADLKDSVNSTLYFIDGMTWPEVLRVYCESDKEYHHVLPYQEAEDYPYGPVENK
IKVLQFLVDQFLTTNIAREELMSEGVIQYDDHCRVCHKLGDLLCCETCSAVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVTDCVAEIQ
KNKPYIRHEPIGYDRSRRKYWFLNRRLIMAGKERNKADRYALDCQEKAYWLVHRCPPGMDNVLDYGLDRVTNPNEVKKQTVVAVKKEIMY
YQQALMRSTVKSSVSLGGIVKYSEQFSSNDAIMSGCLPSNPWITDDTQFWDLNAKLVEIPTKMRVERWAFNFSELIRDPKGRQSFQYFLK
KEFSGENLGFWEACEDLKYGDQSKVKEKAEEIYKLFLAPGARRWINIDGKTMDITVKGLKHPHRYVLDAAQTHIYMLMKKDSYARYLKSP
IYKDMLAKAIEPQETTKKSSTLPFMRRHLRSSPSPVILRQLEEEAKAREAANTVDITQPGQHMAPSPHLTVYTGTCMPPSPSSPFSSSCR
SPRKPFASPSRFIRRPSTTICPSPIRVALESSSGLEQKGECSGSMAPRGPSVTESSEASLDTSWPRSRPRAPPKARMALSFSRFLRRGCL

--------------------------------------------------------------

>10101_10101_3_BPTF-RGS9_BPTF_chr17_65850877_ENST00000306378_RGS9_chr17_63164317_ENST00000449996_length(amino acids)=983AA_BP=6
MRGRRGRPPKQPAAPAAERCAPAPPPPPPPPTSGPIGGLRSRHRGSSRGRWAAAQAEVAPKTRLSSPRGGSSSRRKPPPPPPAPPSTSAP
GRGGRGGGGGRTGGGGGGGHLARTTAARRAVNKVVYDDHESEEEEEEEDMVSEEEEEEDGDAEETQDSEDDEEDEMEEDDDDSDYPEEME
DDDDDASYCTESSFRSHSTYSSTPGRRKPRVHRPRSPILEEKDIPPLEFPKSSEDLMVPNEHIMNVIAIYEVLRNFGTVLRLSPFRFEDF
CAALVSQEQCTLMAEMHVVLLKAVLREEDTSNTTFGPADLKDSVNSTLYFIDGMTWPEVLRVYCESDKEYHHVLPYQEAEDYPYGPVENK
IKVLQFLVDQFLTTNIAREELMSEGVIQYDDHCRVCHKLGDLLCCETCSAVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVTDCVAEIQ
KNKPYIRHEPIGYDRSRRKYWFLNRRLIMAGKERNKADRYALDCQEKAYWLVHRCPPGMDNVLDYGLDRVTNPNEVKKQTVVAVKKEIMY
YQQALMRSTVKSSVSLGGIVKYSEQFSSNDAIMSGCLPSNPWITDDTQFWDLNAKLVEIPTKMRVERWAFNFSELIRDPKGRQSFQYFLK
KEFSGENLGFWEACEDLKYGDQSKVKEKAEEIYKLFLAPGARRWINIDGKTMDITVKGLKHPHRYVLDAAQTHIYMLMKKDSYARYLKSP
IYKDMLAKAIEPQETTKKSSTLPFMRRHLRSSPSPVILRQLEEEAKAREAANTVDITQPGQHMAPSPHLTVYTGTCMPPSPSSPFSSSCR
SPRKPFASPSRFIRRPSTTICPSPIRVALESSSGLEQKGECSGSMAPRGPSVTESSEASLDTSWPRSRPRAPPKARMALSFSRFLRRGCL

--------------------------------------------------------------

>10101_10101_4_BPTF-RGS9_BPTF_chr17_65850877_ENST00000321892_RGS9_chr17_63164317_ENST00000262406_length(amino acids)=986AA_BP=6
MRGRRGRPPKQPAAPAAERCAPAPPPPPPPPTSGPIGGLRSRHRGSSRGRWAAAQAEVAPKTRLSSPRGGSSSRRKPPPPPPAPPSTSAP
GRGGRGGGGGRTGGGGGGGHLARTTAARRAVNKVVYDDHESEEEEEEEDMVSEEEEEEDGDAEETQDSEDDEEDEMEEDDDDSDYPEEME
DDDDDASYCTESSFRSHSTYSSTPGRRKPRVHRPRSPILEEKDIPPLEFPKSSEDLMVPNEHIMNVIAIYEVLRNFGTVLRLSPFRFEDF
CAALVSQEQCTLMAEMHVVLLKAVLREEDTSNTTFGPADLKDSVNSTLYFIDGMTWPEVLRVYCESDKEYHHVLPYQEAEDYPYGPVENK
IKVLQFLVDQFLTTNIAREELMSEGVIQYDDHCRVCHKLGDLLCCETCSAVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVTDCVAEIQ
KNKPYIRHEPIGYDRSRRKYWFLNRRLIMAGKERNKADRYALDCQEKAYWLVHRCPPGMDNVLDYGLDRVTNPNEVKVNQKQTVVAVKKE
IMYYQQALMRSTVKSSVSLGGIVKYSEQFSSNDAIMSGCLPSNPWITDDTQFWDLNAKLVEIPTKMRVERWAFNFSELIRDPKGRQSFQY
FLKKEFSGENLGFWEACEDLKYGDQSKVKEKAEEIYKLFLAPGARRWINIDGKTMDITVKGLKHPHRYVLDAAQTHIYMLMKKDSYARYL
KSPIYKDMLAKAIEPQETTKKSSTLPFMRRHLRSSPSPVILRQLEEEAKAREAANTVDITQPGQHMAPSPHLTVYTGTCMPPSPSSPFSS
SCRSPRKPFASPSRFIRRPSTTICPSPIRVALESSSGLEQKGECSGSMAPRGPSVTESSEASLDTSWPRSRPRAPPKARMALSFSRFLRR

--------------------------------------------------------------

>10101_10101_5_BPTF-RGS9_BPTF_chr17_65850877_ENST00000321892_RGS9_chr17_63164317_ENST00000443584_length(amino acids)=940AA_BP=6
MRGRRGRPPKQPAAPAAERCAPAPPPPPPPPTSGPIGGLRSRHRGSSRGRWAAAQAEVAPKTRLSSPRGGSSSRRKPPPPPPAPPSTSAP
GRGGRGGGGGRTGGGGGGGHLARTTAARRAVNKVVYDDHESEEEEEEEDMVSEEEEEEDGDAEETQDSEDDEEDEMEEDDDDSDYPEEME
DDDDDASYCTESSFRSHSTYSSTPGRRKPRVHRPRSPILEEKDIPPLEFPKSSEDLMVPNEHIMNVIAIYEVLRNFGTVLRLSPFRFEDF
CAALVSQEQCTLMAEMHVVLLKAVLREEDTSNTTFGPADLKDSVNSTLYFIDGMTWPEVLRVYCESDKEYHHVLPYQEAEDYPYGPVENK
IKVLQFLVDQFLTTNIAREELMSEGVIQYDDHCRVCHKLGDLLCCETCSAVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVTDCVAEIQ
KNKPYIRHEPIGYDRSRRKYWFLNRRLIMAGKERNKADRYALDCQEKAYWLVHRCPPGMDNVLDYGLDRVTNPNEVKKQTVVAVKKEIMY
YQQALMRSTVKSSVSLGGIVKYSEQFSSNDAIMSGCLPSNPWITDDTQFWDLNAKLVEIPTKMRVERWAFNFSELIRDPKGRQSFQYFLK
KEFSGENLGFWEACEDLKYGDQSKVKEKAEEIYKLFLAPGARRWINIDGKTMDITVKGLKHPHRYVLDAAQTHIYMLMKKDSYARYLKSP
IYKDMLAKAIEPQETTKKSSTLPFMRRHLRSSPSPVILRQLEEEAKAREAANTVDITQPGQHMAPSPHLTVYTGTCMPPSPSSPFSSSCR
SPRKPFASPSRFIRRPSTTICPSPIRVALESSSGLEQKGECSGSMAPRGPSVTESSEASLDTSWPRSRPRAPPKARMALSFSRFLRRGCL

--------------------------------------------------------------

>10101_10101_6_BPTF-RGS9_BPTF_chr17_65850877_ENST00000321892_RGS9_chr17_63164317_ENST00000449996_length(amino acids)=983AA_BP=6
MRGRRGRPPKQPAAPAAERCAPAPPPPPPPPTSGPIGGLRSRHRGSSRGRWAAAQAEVAPKTRLSSPRGGSSSRRKPPPPPPAPPSTSAP
GRGGRGGGGGRTGGGGGGGHLARTTAARRAVNKVVYDDHESEEEEEEEDMVSEEEEEEDGDAEETQDSEDDEEDEMEEDDDDSDYPEEME
DDDDDASYCTESSFRSHSTYSSTPGRRKPRVHRPRSPILEEKDIPPLEFPKSSEDLMVPNEHIMNVIAIYEVLRNFGTVLRLSPFRFEDF
CAALVSQEQCTLMAEMHVVLLKAVLREEDTSNTTFGPADLKDSVNSTLYFIDGMTWPEVLRVYCESDKEYHHVLPYQEAEDYPYGPVENK
IKVLQFLVDQFLTTNIAREELMSEGVIQYDDHCRVCHKLGDLLCCETCSAVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVTDCVAEIQ
KNKPYIRHEPIGYDRSRRKYWFLNRRLIMAGKERNKADRYALDCQEKAYWLVHRCPPGMDNVLDYGLDRVTNPNEVKKQTVVAVKKEIMY
YQQALMRSTVKSSVSLGGIVKYSEQFSSNDAIMSGCLPSNPWITDDTQFWDLNAKLVEIPTKMRVERWAFNFSELIRDPKGRQSFQYFLK
KEFSGENLGFWEACEDLKYGDQSKVKEKAEEIYKLFLAPGARRWINIDGKTMDITVKGLKHPHRYVLDAAQTHIYMLMKKDSYARYLKSP
IYKDMLAKAIEPQETTKKSSTLPFMRRHLRSSPSPVILRQLEEEAKAREAANTVDITQPGQHMAPSPHLTVYTGTCMPPSPSSPFSSSCR
SPRKPFASPSRFIRRPSTTICPSPIRVALESSSGLEQKGECSGSMAPRGPSVTESSEASLDTSWPRSRPRAPPKARMALSFSRFLRRGCL

--------------------------------------------------------------

>10101_10101_7_BPTF-RGS9_BPTF_chr17_65850877_ENST00000335221_RGS9_chr17_63164317_ENST00000262406_length(amino acids)=986AA_BP=6
MRGRRGRPPKQPAAPAAERCAPAPPPPPPPPTSGPIGGLRSRHRGSSRGRWAAAQAEVAPKTRLSSPRGGSSSRRKPPPPPPAPPSTSAP
GRGGRGGGGGRTGGGGGGGHLARTTAARRAVNKVVYDDHESEEEEEEEDMVSEEEEEEDGDAEETQDSEDDEEDEMEEDDDDSDYPEEME
DDDDDASYCTESSFRSHSTYSSTPGRRKPRVHRPRSPILEEKDIPPLEFPKSSEDLMVPNEHIMNVIAIYEVLRNFGTVLRLSPFRFEDF
CAALVSQEQCTLMAEMHVVLLKAVLREEDTSNTTFGPADLKDSVNSTLYFIDGMTWPEVLRVYCESDKEYHHVLPYQEAEDYPYGPVENK
IKVLQFLVDQFLTTNIAREELMSEGVIQYDDHCRVCHKLGDLLCCETCSAVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVTDCVAEIQ
KNKPYIRHEPIGYDRSRRKYWFLNRRLIMAGKERNKADRYALDCQEKAYWLVHRCPPGMDNVLDYGLDRVTNPNEVKVNQKQTVVAVKKE
IMYYQQALMRSTVKSSVSLGGIVKYSEQFSSNDAIMSGCLPSNPWITDDTQFWDLNAKLVEIPTKMRVERWAFNFSELIRDPKGRQSFQY
FLKKEFSGENLGFWEACEDLKYGDQSKVKEKAEEIYKLFLAPGARRWINIDGKTMDITVKGLKHPHRYVLDAAQTHIYMLMKKDSYARYL
KSPIYKDMLAKAIEPQETTKKSSTLPFMRRHLRSSPSPVILRQLEEEAKAREAANTVDITQPGQHMAPSPHLTVYTGTCMPPSPSSPFSS
SCRSPRKPFASPSRFIRRPSTTICPSPIRVALESSSGLEQKGECSGSMAPRGPSVTESSEASLDTSWPRSRPRAPPKARMALSFSRFLRR

--------------------------------------------------------------

>10101_10101_8_BPTF-RGS9_BPTF_chr17_65850877_ENST00000335221_RGS9_chr17_63164317_ENST00000443584_length(amino acids)=940AA_BP=6
MRGRRGRPPKQPAAPAAERCAPAPPPPPPPPTSGPIGGLRSRHRGSSRGRWAAAQAEVAPKTRLSSPRGGSSSRRKPPPPPPAPPSTSAP
GRGGRGGGGGRTGGGGGGGHLARTTAARRAVNKVVYDDHESEEEEEEEDMVSEEEEEEDGDAEETQDSEDDEEDEMEEDDDDSDYPEEME
DDDDDASYCTESSFRSHSTYSSTPGRRKPRVHRPRSPILEEKDIPPLEFPKSSEDLMVPNEHIMNVIAIYEVLRNFGTVLRLSPFRFEDF
CAALVSQEQCTLMAEMHVVLLKAVLREEDTSNTTFGPADLKDSVNSTLYFIDGMTWPEVLRVYCESDKEYHHVLPYQEAEDYPYGPVENK
IKVLQFLVDQFLTTNIAREELMSEGVIQYDDHCRVCHKLGDLLCCETCSAVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVTDCVAEIQ
KNKPYIRHEPIGYDRSRRKYWFLNRRLIMAGKERNKADRYALDCQEKAYWLVHRCPPGMDNVLDYGLDRVTNPNEVKKQTVVAVKKEIMY
YQQALMRSTVKSSVSLGGIVKYSEQFSSNDAIMSGCLPSNPWITDDTQFWDLNAKLVEIPTKMRVERWAFNFSELIRDPKGRQSFQYFLK
KEFSGENLGFWEACEDLKYGDQSKVKEKAEEIYKLFLAPGARRWINIDGKTMDITVKGLKHPHRYVLDAAQTHIYMLMKKDSYARYLKSP
IYKDMLAKAIEPQETTKKSSTLPFMRRHLRSSPSPVILRQLEEEAKAREAANTVDITQPGQHMAPSPHLTVYTGTCMPPSPSSPFSSSCR
SPRKPFASPSRFIRRPSTTICPSPIRVALESSSGLEQKGECSGSMAPRGPSVTESSEASLDTSWPRSRPRAPPKARMALSFSRFLRRGCL

--------------------------------------------------------------

>10101_10101_9_BPTF-RGS9_BPTF_chr17_65850877_ENST00000335221_RGS9_chr17_63164317_ENST00000449996_length(amino acids)=983AA_BP=6
MRGRRGRPPKQPAAPAAERCAPAPPPPPPPPTSGPIGGLRSRHRGSSRGRWAAAQAEVAPKTRLSSPRGGSSSRRKPPPPPPAPPSTSAP
GRGGRGGGGGRTGGGGGGGHLARTTAARRAVNKVVYDDHESEEEEEEEDMVSEEEEEEDGDAEETQDSEDDEEDEMEEDDDDSDYPEEME
DDDDDASYCTESSFRSHSTYSSTPGRRKPRVHRPRSPILEEKDIPPLEFPKSSEDLMVPNEHIMNVIAIYEVLRNFGTVLRLSPFRFEDF
CAALVSQEQCTLMAEMHVVLLKAVLREEDTSNTTFGPADLKDSVNSTLYFIDGMTWPEVLRVYCESDKEYHHVLPYQEAEDYPYGPVENK
IKVLQFLVDQFLTTNIAREELMSEGVIQYDDHCRVCHKLGDLLCCETCSAVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVTDCVAEIQ
KNKPYIRHEPIGYDRSRRKYWFLNRRLIMAGKERNKADRYALDCQEKAYWLVHRCPPGMDNVLDYGLDRVTNPNEVKKQTVVAVKKEIMY
YQQALMRSTVKSSVSLGGIVKYSEQFSSNDAIMSGCLPSNPWITDDTQFWDLNAKLVEIPTKMRVERWAFNFSELIRDPKGRQSFQYFLK
KEFSGENLGFWEACEDLKYGDQSKVKEKAEEIYKLFLAPGARRWINIDGKTMDITVKGLKHPHRYVLDAAQTHIYMLMKKDSYARYLKSP
IYKDMLAKAIEPQETTKKSSTLPFMRRHLRSSPSPVILRQLEEEAKAREAANTVDITQPGQHMAPSPHLTVYTGTCMPPSPSSPFSSSCR
SPRKPFASPSRFIRRPSTTICPSPIRVALESSSGLEQKGECSGSMAPRGPSVTESSEASLDTSWPRSRPRAPPKARMALSFSRFLRRGCL

--------------------------------------------------------------

>10101_10101_10_BPTF-RGS9_BPTF_chr17_65850877_ENST00000424123_RGS9_chr17_63164317_ENST00000262406_length(amino acids)=847AA_BP=340
MVSEEEEEEDGDAEETQDSEDDEEDEMEEDDDDSDYPEEMEDDDDDASYCTESSFRSHSTYSSTPGRRKPRVHRPRSPILEEKDIPPLEF
PKSSEDLMVPNEHIMNVIAIYEVLRNFGTVLRLSPFRFEDFCAALVSQEQCTLMAEMHVVLLKAVLREEDTSNTTFGPADLKDSVNSTLY
FIDGMTWPEVLRVYCESDKEYHHVLPYQEAEDYPYGPVENKIKVLQFLVDQFLTTNIAREELMSEGVIQYDDHCRVCHKLGDLLCCETCS
AVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVTDCVAEIQKNKPYIRHEPIGYDRSRRKYWFLNRRLIMAGKERNKADRYALDCQEKAY
WLVHRCPPGMDNVLDYGLDRVTNPNEVKVNQKQTVVAVKKEIMYYQQALMRSTVKSSVSLGGIVKYSEQFSSNDAIMSGCLPSNPWITDD
TQFWDLNAKLVEIPTKMRVERWAFNFSELIRDPKGRQSFQYFLKKEFSGENLGFWEACEDLKYGDQSKVKEKAEEIYKLFLAPGARRWIN
IDGKTMDITVKGLKHPHRYVLDAAQTHIYMLMKKDSYARYLKSPIYKDMLAKAIEPQETTKKSSTLPFMRRHLRSSPSPVILRQLEEEAK
AREAANTVDITQPGQHMAPSPHLTVYTGTCMPPSPSSPFSSSCRSPRKPFASPSRFIRRPSTTICPSPIRVALESSSGLEQKGECSGSMA
PRGPSVTESSEASLDTSWPRSRPRAPPKARMALSFSRFLRRGCLASPVFARLSPKCPAVSHGRVQPLGDVGQQLPRLKSKRVANFFQIKM

--------------------------------------------------------------

>10101_10101_11_BPTF-RGS9_BPTF_chr17_65850877_ENST00000424123_RGS9_chr17_63164317_ENST00000443584_length(amino acids)=801AA_BP=340
MVSEEEEEEDGDAEETQDSEDDEEDEMEEDDDDSDYPEEMEDDDDDASYCTESSFRSHSTYSSTPGRRKPRVHRPRSPILEEKDIPPLEF
PKSSEDLMVPNEHIMNVIAIYEVLRNFGTVLRLSPFRFEDFCAALVSQEQCTLMAEMHVVLLKAVLREEDTSNTTFGPADLKDSVNSTLY
FIDGMTWPEVLRVYCESDKEYHHVLPYQEAEDYPYGPVENKIKVLQFLVDQFLTTNIAREELMSEGVIQYDDHCRVCHKLGDLLCCETCS
AVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVTDCVAEIQKNKPYIRHEPIGYDRSRRKYWFLNRRLIMAGKERNKADRYALDCQEKAY
WLVHRCPPGMDNVLDYGLDRVTNPNEVKKQTVVAVKKEIMYYQQALMRSTVKSSVSLGGIVKYSEQFSSNDAIMSGCLPSNPWITDDTQF
WDLNAKLVEIPTKMRVERWAFNFSELIRDPKGRQSFQYFLKKEFSGENLGFWEACEDLKYGDQSKVKEKAEEIYKLFLAPGARRWINIDG
KTMDITVKGLKHPHRYVLDAAQTHIYMLMKKDSYARYLKSPIYKDMLAKAIEPQETTKKSSTLPFMRRHLRSSPSPVILRQLEEEAKARE
AANTVDITQPGQHMAPSPHLTVYTGTCMPPSPSSPFSSSCRSPRKPFASPSRFIRRPSTTICPSPIRVALESSSGLEQKGECSGSMAPRG

--------------------------------------------------------------

>10101_10101_12_BPTF-RGS9_BPTF_chr17_65850877_ENST00000424123_RGS9_chr17_63164317_ENST00000449996_length(amino acids)=844AA_BP=340
MVSEEEEEEDGDAEETQDSEDDEEDEMEEDDDDSDYPEEMEDDDDDASYCTESSFRSHSTYSSTPGRRKPRVHRPRSPILEEKDIPPLEF
PKSSEDLMVPNEHIMNVIAIYEVLRNFGTVLRLSPFRFEDFCAALVSQEQCTLMAEMHVVLLKAVLREEDTSNTTFGPADLKDSVNSTLY
FIDGMTWPEVLRVYCESDKEYHHVLPYQEAEDYPYGPVENKIKVLQFLVDQFLTTNIAREELMSEGVIQYDDHCRVCHKLGDLLCCETCS
AVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVTDCVAEIQKNKPYIRHEPIGYDRSRRKYWFLNRRLIMAGKERNKADRYALDCQEKAY
WLVHRCPPGMDNVLDYGLDRVTNPNEVKKQTVVAVKKEIMYYQQALMRSTVKSSVSLGGIVKYSEQFSSNDAIMSGCLPSNPWITDDTQF
WDLNAKLVEIPTKMRVERWAFNFSELIRDPKGRQSFQYFLKKEFSGENLGFWEACEDLKYGDQSKVKEKAEEIYKLFLAPGARRWINIDG
KTMDITVKGLKHPHRYVLDAAQTHIYMLMKKDSYARYLKSPIYKDMLAKAIEPQETTKKSSTLPFMRRHLRSSPSPVILRQLEEEAKARE
AANTVDITQPGQHMAPSPHLTVYTGTCMPPSPSSPFSSSCRSPRKPFASPSRFIRRPSTTICPSPIRVALESSSGLEQKGECSGSMAPRG
PSVTESSEASLDTSWPRSRPRAPPKARMALSFSRFLRRGCLASPVFARLSPKCPAVSHGRVQPLGDVGQQLPRLKSKRVANFFQIKMDVP

--------------------------------------------------------------

>10101_10101_13_BPTF-RGS9_BPTF_chr17_65850878_ENST00000306378_RGS9_chr17_63164317_ENST00000262406_length(amino acids)=986AA_BP=6
MRGRRGRPPKQPAAPAAERCAPAPPPPPPPPTSGPIGGLRSRHRGSSRGRWAAAQAEVAPKTRLSSPRGGSSSRRKPPPPPPAPPSTSAP
GRGGRGGGGGRTGGGGGGGHLARTTAARRAVNKVVYDDHESEEEEEEEDMVSEEEEEEDGDAEETQDSEDDEEDEMEEDDDDSDYPEEME
DDDDDASYCTESSFRSHSTYSSTPGRRKPRVHRPRSPILEEKDIPPLEFPKSSEDLMVPNEHIMNVIAIYEVLRNFGTVLRLSPFRFEDF
CAALVSQEQCTLMAEMHVVLLKAVLREEDTSNTTFGPADLKDSVNSTLYFIDGMTWPEVLRVYCESDKEYHHVLPYQEAEDYPYGPVENK
IKVLQFLVDQFLTTNIAREELMSEGVIQYDDHCRVCHKLGDLLCCETCSAVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVTDCVAEIQ
KNKPYIRHEPIGYDRSRRKYWFLNRRLIMAGKERNKADRYALDCQEKAYWLVHRCPPGMDNVLDYGLDRVTNPNEVKVNQKQTVVAVKKE
IMYYQQALMRSTVKSSVSLGGIVKYSEQFSSNDAIMSGCLPSNPWITDDTQFWDLNAKLVEIPTKMRVERWAFNFSELIRDPKGRQSFQY
FLKKEFSGENLGFWEACEDLKYGDQSKVKEKAEEIYKLFLAPGARRWINIDGKTMDITVKGLKHPHRYVLDAAQTHIYMLMKKDSYARYL
KSPIYKDMLAKAIEPQETTKKSSTLPFMRRHLRSSPSPVILRQLEEEAKAREAANTVDITQPGQHMAPSPHLTVYTGTCMPPSPSSPFSS
SCRSPRKPFASPSRFIRRPSTTICPSPIRVALESSSGLEQKGECSGSMAPRGPSVTESSEASLDTSWPRSRPRAPPKARMALSFSRFLRR

--------------------------------------------------------------

>10101_10101_14_BPTF-RGS9_BPTF_chr17_65850878_ENST00000306378_RGS9_chr17_63164317_ENST00000443584_length(amino acids)=940AA_BP=6
MRGRRGRPPKQPAAPAAERCAPAPPPPPPPPTSGPIGGLRSRHRGSSRGRWAAAQAEVAPKTRLSSPRGGSSSRRKPPPPPPAPPSTSAP
GRGGRGGGGGRTGGGGGGGHLARTTAARRAVNKVVYDDHESEEEEEEEDMVSEEEEEEDGDAEETQDSEDDEEDEMEEDDDDSDYPEEME
DDDDDASYCTESSFRSHSTYSSTPGRRKPRVHRPRSPILEEKDIPPLEFPKSSEDLMVPNEHIMNVIAIYEVLRNFGTVLRLSPFRFEDF
CAALVSQEQCTLMAEMHVVLLKAVLREEDTSNTTFGPADLKDSVNSTLYFIDGMTWPEVLRVYCESDKEYHHVLPYQEAEDYPYGPVENK
IKVLQFLVDQFLTTNIAREELMSEGVIQYDDHCRVCHKLGDLLCCETCSAVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVTDCVAEIQ
KNKPYIRHEPIGYDRSRRKYWFLNRRLIMAGKERNKADRYALDCQEKAYWLVHRCPPGMDNVLDYGLDRVTNPNEVKKQTVVAVKKEIMY
YQQALMRSTVKSSVSLGGIVKYSEQFSSNDAIMSGCLPSNPWITDDTQFWDLNAKLVEIPTKMRVERWAFNFSELIRDPKGRQSFQYFLK
KEFSGENLGFWEACEDLKYGDQSKVKEKAEEIYKLFLAPGARRWINIDGKTMDITVKGLKHPHRYVLDAAQTHIYMLMKKDSYARYLKSP
IYKDMLAKAIEPQETTKKSSTLPFMRRHLRSSPSPVILRQLEEEAKAREAANTVDITQPGQHMAPSPHLTVYTGTCMPPSPSSPFSSSCR
SPRKPFASPSRFIRRPSTTICPSPIRVALESSSGLEQKGECSGSMAPRGPSVTESSEASLDTSWPRSRPRAPPKARMALSFSRFLRRGCL

--------------------------------------------------------------

>10101_10101_15_BPTF-RGS9_BPTF_chr17_65850878_ENST00000306378_RGS9_chr17_63164317_ENST00000449996_length(amino acids)=983AA_BP=6
MRGRRGRPPKQPAAPAAERCAPAPPPPPPPPTSGPIGGLRSRHRGSSRGRWAAAQAEVAPKTRLSSPRGGSSSRRKPPPPPPAPPSTSAP
GRGGRGGGGGRTGGGGGGGHLARTTAARRAVNKVVYDDHESEEEEEEEDMVSEEEEEEDGDAEETQDSEDDEEDEMEEDDDDSDYPEEME
DDDDDASYCTESSFRSHSTYSSTPGRRKPRVHRPRSPILEEKDIPPLEFPKSSEDLMVPNEHIMNVIAIYEVLRNFGTVLRLSPFRFEDF
CAALVSQEQCTLMAEMHVVLLKAVLREEDTSNTTFGPADLKDSVNSTLYFIDGMTWPEVLRVYCESDKEYHHVLPYQEAEDYPYGPVENK
IKVLQFLVDQFLTTNIAREELMSEGVIQYDDHCRVCHKLGDLLCCETCSAVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVTDCVAEIQ
KNKPYIRHEPIGYDRSRRKYWFLNRRLIMAGKERNKADRYALDCQEKAYWLVHRCPPGMDNVLDYGLDRVTNPNEVKKQTVVAVKKEIMY
YQQALMRSTVKSSVSLGGIVKYSEQFSSNDAIMSGCLPSNPWITDDTQFWDLNAKLVEIPTKMRVERWAFNFSELIRDPKGRQSFQYFLK
KEFSGENLGFWEACEDLKYGDQSKVKEKAEEIYKLFLAPGARRWINIDGKTMDITVKGLKHPHRYVLDAAQTHIYMLMKKDSYARYLKSP
IYKDMLAKAIEPQETTKKSSTLPFMRRHLRSSPSPVILRQLEEEAKAREAANTVDITQPGQHMAPSPHLTVYTGTCMPPSPSSPFSSSCR
SPRKPFASPSRFIRRPSTTICPSPIRVALESSSGLEQKGECSGSMAPRGPSVTESSEASLDTSWPRSRPRAPPKARMALSFSRFLRRGCL

--------------------------------------------------------------

>10101_10101_16_BPTF-RGS9_BPTF_chr17_65850878_ENST00000306378_RGS9_chr17_63164318_ENST00000262406_length(amino acids)=986AA_BP=6
MRGRRGRPPKQPAAPAAERCAPAPPPPPPPPTSGPIGGLRSRHRGSSRGRWAAAQAEVAPKTRLSSPRGGSSSRRKPPPPPPAPPSTSAP
GRGGRGGGGGRTGGGGGGGHLARTTAARRAVNKVVYDDHESEEEEEEEDMVSEEEEEEDGDAEETQDSEDDEEDEMEEDDDDSDYPEEME
DDDDDASYCTESSFRSHSTYSSTPGRRKPRVHRPRSPILEEKDIPPLEFPKSSEDLMVPNEHIMNVIAIYEVLRNFGTVLRLSPFRFEDF
CAALVSQEQCTLMAEMHVVLLKAVLREEDTSNTTFGPADLKDSVNSTLYFIDGMTWPEVLRVYCESDKEYHHVLPYQEAEDYPYGPVENK
IKVLQFLVDQFLTTNIAREELMSEGVIQYDDHCRVCHKLGDLLCCETCSAVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVTDCVAEIQ
KNKPYIRHEPIGYDRSRRKYWFLNRRLIMAGKERNKADRYALDCQEKAYWLVHRCPPGMDNVLDYGLDRVTNPNEVKVNQKQTVVAVKKE
IMYYQQALMRSTVKSSVSLGGIVKYSEQFSSNDAIMSGCLPSNPWITDDTQFWDLNAKLVEIPTKMRVERWAFNFSELIRDPKGRQSFQY
FLKKEFSGENLGFWEACEDLKYGDQSKVKEKAEEIYKLFLAPGARRWINIDGKTMDITVKGLKHPHRYVLDAAQTHIYMLMKKDSYARYL
KSPIYKDMLAKAIEPQETTKKSSTLPFMRRHLRSSPSPVILRQLEEEAKAREAANTVDITQPGQHMAPSPHLTVYTGTCMPPSPSSPFSS
SCRSPRKPFASPSRFIRRPSTTICPSPIRVALESSSGLEQKGECSGSMAPRGPSVTESSEASLDTSWPRSRPRAPPKARMALSFSRFLRR

--------------------------------------------------------------

>10101_10101_17_BPTF-RGS9_BPTF_chr17_65850878_ENST00000306378_RGS9_chr17_63164318_ENST00000443584_length(amino acids)=940AA_BP=6
MRGRRGRPPKQPAAPAAERCAPAPPPPPPPPTSGPIGGLRSRHRGSSRGRWAAAQAEVAPKTRLSSPRGGSSSRRKPPPPPPAPPSTSAP
GRGGRGGGGGRTGGGGGGGHLARTTAARRAVNKVVYDDHESEEEEEEEDMVSEEEEEEDGDAEETQDSEDDEEDEMEEDDDDSDYPEEME
DDDDDASYCTESSFRSHSTYSSTPGRRKPRVHRPRSPILEEKDIPPLEFPKSSEDLMVPNEHIMNVIAIYEVLRNFGTVLRLSPFRFEDF
CAALVSQEQCTLMAEMHVVLLKAVLREEDTSNTTFGPADLKDSVNSTLYFIDGMTWPEVLRVYCESDKEYHHVLPYQEAEDYPYGPVENK
IKVLQFLVDQFLTTNIAREELMSEGVIQYDDHCRVCHKLGDLLCCETCSAVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVTDCVAEIQ
KNKPYIRHEPIGYDRSRRKYWFLNRRLIMAGKERNKADRYALDCQEKAYWLVHRCPPGMDNVLDYGLDRVTNPNEVKKQTVVAVKKEIMY
YQQALMRSTVKSSVSLGGIVKYSEQFSSNDAIMSGCLPSNPWITDDTQFWDLNAKLVEIPTKMRVERWAFNFSELIRDPKGRQSFQYFLK
KEFSGENLGFWEACEDLKYGDQSKVKEKAEEIYKLFLAPGARRWINIDGKTMDITVKGLKHPHRYVLDAAQTHIYMLMKKDSYARYLKSP
IYKDMLAKAIEPQETTKKSSTLPFMRRHLRSSPSPVILRQLEEEAKAREAANTVDITQPGQHMAPSPHLTVYTGTCMPPSPSSPFSSSCR
SPRKPFASPSRFIRRPSTTICPSPIRVALESSSGLEQKGECSGSMAPRGPSVTESSEASLDTSWPRSRPRAPPKARMALSFSRFLRRGCL

--------------------------------------------------------------

>10101_10101_18_BPTF-RGS9_BPTF_chr17_65850878_ENST00000306378_RGS9_chr17_63164318_ENST00000449996_length(amino acids)=983AA_BP=6
MRGRRGRPPKQPAAPAAERCAPAPPPPPPPPTSGPIGGLRSRHRGSSRGRWAAAQAEVAPKTRLSSPRGGSSSRRKPPPPPPAPPSTSAP
GRGGRGGGGGRTGGGGGGGHLARTTAARRAVNKVVYDDHESEEEEEEEDMVSEEEEEEDGDAEETQDSEDDEEDEMEEDDDDSDYPEEME
DDDDDASYCTESSFRSHSTYSSTPGRRKPRVHRPRSPILEEKDIPPLEFPKSSEDLMVPNEHIMNVIAIYEVLRNFGTVLRLSPFRFEDF
CAALVSQEQCTLMAEMHVVLLKAVLREEDTSNTTFGPADLKDSVNSTLYFIDGMTWPEVLRVYCESDKEYHHVLPYQEAEDYPYGPVENK
IKVLQFLVDQFLTTNIAREELMSEGVIQYDDHCRVCHKLGDLLCCETCSAVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVTDCVAEIQ
KNKPYIRHEPIGYDRSRRKYWFLNRRLIMAGKERNKADRYALDCQEKAYWLVHRCPPGMDNVLDYGLDRVTNPNEVKKQTVVAVKKEIMY
YQQALMRSTVKSSVSLGGIVKYSEQFSSNDAIMSGCLPSNPWITDDTQFWDLNAKLVEIPTKMRVERWAFNFSELIRDPKGRQSFQYFLK
KEFSGENLGFWEACEDLKYGDQSKVKEKAEEIYKLFLAPGARRWINIDGKTMDITVKGLKHPHRYVLDAAQTHIYMLMKKDSYARYLKSP
IYKDMLAKAIEPQETTKKSSTLPFMRRHLRSSPSPVILRQLEEEAKAREAANTVDITQPGQHMAPSPHLTVYTGTCMPPSPSSPFSSSCR
SPRKPFASPSRFIRRPSTTICPSPIRVALESSSGLEQKGECSGSMAPRGPSVTESSEASLDTSWPRSRPRAPPKARMALSFSRFLRRGCL

--------------------------------------------------------------

>10101_10101_19_BPTF-RGS9_BPTF_chr17_65850878_ENST00000321892_RGS9_chr17_63164317_ENST00000262406_length(amino acids)=986AA_BP=6
MRGRRGRPPKQPAAPAAERCAPAPPPPPPPPTSGPIGGLRSRHRGSSRGRWAAAQAEVAPKTRLSSPRGGSSSRRKPPPPPPAPPSTSAP
GRGGRGGGGGRTGGGGGGGHLARTTAARRAVNKVVYDDHESEEEEEEEDMVSEEEEEEDGDAEETQDSEDDEEDEMEEDDDDSDYPEEME
DDDDDASYCTESSFRSHSTYSSTPGRRKPRVHRPRSPILEEKDIPPLEFPKSSEDLMVPNEHIMNVIAIYEVLRNFGTVLRLSPFRFEDF
CAALVSQEQCTLMAEMHVVLLKAVLREEDTSNTTFGPADLKDSVNSTLYFIDGMTWPEVLRVYCESDKEYHHVLPYQEAEDYPYGPVENK
IKVLQFLVDQFLTTNIAREELMSEGVIQYDDHCRVCHKLGDLLCCETCSAVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVTDCVAEIQ
KNKPYIRHEPIGYDRSRRKYWFLNRRLIMAGKERNKADRYALDCQEKAYWLVHRCPPGMDNVLDYGLDRVTNPNEVKVNQKQTVVAVKKE
IMYYQQALMRSTVKSSVSLGGIVKYSEQFSSNDAIMSGCLPSNPWITDDTQFWDLNAKLVEIPTKMRVERWAFNFSELIRDPKGRQSFQY
FLKKEFSGENLGFWEACEDLKYGDQSKVKEKAEEIYKLFLAPGARRWINIDGKTMDITVKGLKHPHRYVLDAAQTHIYMLMKKDSYARYL
KSPIYKDMLAKAIEPQETTKKSSTLPFMRRHLRSSPSPVILRQLEEEAKAREAANTVDITQPGQHMAPSPHLTVYTGTCMPPSPSSPFSS
SCRSPRKPFASPSRFIRRPSTTICPSPIRVALESSSGLEQKGECSGSMAPRGPSVTESSEASLDTSWPRSRPRAPPKARMALSFSRFLRR

--------------------------------------------------------------

>10101_10101_20_BPTF-RGS9_BPTF_chr17_65850878_ENST00000321892_RGS9_chr17_63164317_ENST00000443584_length(amino acids)=940AA_BP=6
MRGRRGRPPKQPAAPAAERCAPAPPPPPPPPTSGPIGGLRSRHRGSSRGRWAAAQAEVAPKTRLSSPRGGSSSRRKPPPPPPAPPSTSAP
GRGGRGGGGGRTGGGGGGGHLARTTAARRAVNKVVYDDHESEEEEEEEDMVSEEEEEEDGDAEETQDSEDDEEDEMEEDDDDSDYPEEME
DDDDDASYCTESSFRSHSTYSSTPGRRKPRVHRPRSPILEEKDIPPLEFPKSSEDLMVPNEHIMNVIAIYEVLRNFGTVLRLSPFRFEDF
CAALVSQEQCTLMAEMHVVLLKAVLREEDTSNTTFGPADLKDSVNSTLYFIDGMTWPEVLRVYCESDKEYHHVLPYQEAEDYPYGPVENK
IKVLQFLVDQFLTTNIAREELMSEGVIQYDDHCRVCHKLGDLLCCETCSAVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVTDCVAEIQ
KNKPYIRHEPIGYDRSRRKYWFLNRRLIMAGKERNKADRYALDCQEKAYWLVHRCPPGMDNVLDYGLDRVTNPNEVKKQTVVAVKKEIMY
YQQALMRSTVKSSVSLGGIVKYSEQFSSNDAIMSGCLPSNPWITDDTQFWDLNAKLVEIPTKMRVERWAFNFSELIRDPKGRQSFQYFLK
KEFSGENLGFWEACEDLKYGDQSKVKEKAEEIYKLFLAPGARRWINIDGKTMDITVKGLKHPHRYVLDAAQTHIYMLMKKDSYARYLKSP
IYKDMLAKAIEPQETTKKSSTLPFMRRHLRSSPSPVILRQLEEEAKAREAANTVDITQPGQHMAPSPHLTVYTGTCMPPSPSSPFSSSCR
SPRKPFASPSRFIRRPSTTICPSPIRVALESSSGLEQKGECSGSMAPRGPSVTESSEASLDTSWPRSRPRAPPKARMALSFSRFLRRGCL

--------------------------------------------------------------

>10101_10101_21_BPTF-RGS9_BPTF_chr17_65850878_ENST00000321892_RGS9_chr17_63164317_ENST00000449996_length(amino acids)=983AA_BP=6
MRGRRGRPPKQPAAPAAERCAPAPPPPPPPPTSGPIGGLRSRHRGSSRGRWAAAQAEVAPKTRLSSPRGGSSSRRKPPPPPPAPPSTSAP
GRGGRGGGGGRTGGGGGGGHLARTTAARRAVNKVVYDDHESEEEEEEEDMVSEEEEEEDGDAEETQDSEDDEEDEMEEDDDDSDYPEEME
DDDDDASYCTESSFRSHSTYSSTPGRRKPRVHRPRSPILEEKDIPPLEFPKSSEDLMVPNEHIMNVIAIYEVLRNFGTVLRLSPFRFEDF
CAALVSQEQCTLMAEMHVVLLKAVLREEDTSNTTFGPADLKDSVNSTLYFIDGMTWPEVLRVYCESDKEYHHVLPYQEAEDYPYGPVENK
IKVLQFLVDQFLTTNIAREELMSEGVIQYDDHCRVCHKLGDLLCCETCSAVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVTDCVAEIQ
KNKPYIRHEPIGYDRSRRKYWFLNRRLIMAGKERNKADRYALDCQEKAYWLVHRCPPGMDNVLDYGLDRVTNPNEVKKQTVVAVKKEIMY
YQQALMRSTVKSSVSLGGIVKYSEQFSSNDAIMSGCLPSNPWITDDTQFWDLNAKLVEIPTKMRVERWAFNFSELIRDPKGRQSFQYFLK
KEFSGENLGFWEACEDLKYGDQSKVKEKAEEIYKLFLAPGARRWINIDGKTMDITVKGLKHPHRYVLDAAQTHIYMLMKKDSYARYLKSP
IYKDMLAKAIEPQETTKKSSTLPFMRRHLRSSPSPVILRQLEEEAKAREAANTVDITQPGQHMAPSPHLTVYTGTCMPPSPSSPFSSSCR
SPRKPFASPSRFIRRPSTTICPSPIRVALESSSGLEQKGECSGSMAPRGPSVTESSEASLDTSWPRSRPRAPPKARMALSFSRFLRRGCL

--------------------------------------------------------------

>10101_10101_22_BPTF-RGS9_BPTF_chr17_65850878_ENST00000321892_RGS9_chr17_63164318_ENST00000262406_length(amino acids)=986AA_BP=6
MRGRRGRPPKQPAAPAAERCAPAPPPPPPPPTSGPIGGLRSRHRGSSRGRWAAAQAEVAPKTRLSSPRGGSSSRRKPPPPPPAPPSTSAP
GRGGRGGGGGRTGGGGGGGHLARTTAARRAVNKVVYDDHESEEEEEEEDMVSEEEEEEDGDAEETQDSEDDEEDEMEEDDDDSDYPEEME
DDDDDASYCTESSFRSHSTYSSTPGRRKPRVHRPRSPILEEKDIPPLEFPKSSEDLMVPNEHIMNVIAIYEVLRNFGTVLRLSPFRFEDF
CAALVSQEQCTLMAEMHVVLLKAVLREEDTSNTTFGPADLKDSVNSTLYFIDGMTWPEVLRVYCESDKEYHHVLPYQEAEDYPYGPVENK
IKVLQFLVDQFLTTNIAREELMSEGVIQYDDHCRVCHKLGDLLCCETCSAVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVTDCVAEIQ
KNKPYIRHEPIGYDRSRRKYWFLNRRLIMAGKERNKADRYALDCQEKAYWLVHRCPPGMDNVLDYGLDRVTNPNEVKVNQKQTVVAVKKE
IMYYQQALMRSTVKSSVSLGGIVKYSEQFSSNDAIMSGCLPSNPWITDDTQFWDLNAKLVEIPTKMRVERWAFNFSELIRDPKGRQSFQY
FLKKEFSGENLGFWEACEDLKYGDQSKVKEKAEEIYKLFLAPGARRWINIDGKTMDITVKGLKHPHRYVLDAAQTHIYMLMKKDSYARYL
KSPIYKDMLAKAIEPQETTKKSSTLPFMRRHLRSSPSPVILRQLEEEAKAREAANTVDITQPGQHMAPSPHLTVYTGTCMPPSPSSPFSS
SCRSPRKPFASPSRFIRRPSTTICPSPIRVALESSSGLEQKGECSGSMAPRGPSVTESSEASLDTSWPRSRPRAPPKARMALSFSRFLRR

--------------------------------------------------------------

>10101_10101_23_BPTF-RGS9_BPTF_chr17_65850878_ENST00000321892_RGS9_chr17_63164318_ENST00000443584_length(amino acids)=940AA_BP=6
MRGRRGRPPKQPAAPAAERCAPAPPPPPPPPTSGPIGGLRSRHRGSSRGRWAAAQAEVAPKTRLSSPRGGSSSRRKPPPPPPAPPSTSAP
GRGGRGGGGGRTGGGGGGGHLARTTAARRAVNKVVYDDHESEEEEEEEDMVSEEEEEEDGDAEETQDSEDDEEDEMEEDDDDSDYPEEME
DDDDDASYCTESSFRSHSTYSSTPGRRKPRVHRPRSPILEEKDIPPLEFPKSSEDLMVPNEHIMNVIAIYEVLRNFGTVLRLSPFRFEDF
CAALVSQEQCTLMAEMHVVLLKAVLREEDTSNTTFGPADLKDSVNSTLYFIDGMTWPEVLRVYCESDKEYHHVLPYQEAEDYPYGPVENK
IKVLQFLVDQFLTTNIAREELMSEGVIQYDDHCRVCHKLGDLLCCETCSAVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVTDCVAEIQ
KNKPYIRHEPIGYDRSRRKYWFLNRRLIMAGKERNKADRYALDCQEKAYWLVHRCPPGMDNVLDYGLDRVTNPNEVKKQTVVAVKKEIMY
YQQALMRSTVKSSVSLGGIVKYSEQFSSNDAIMSGCLPSNPWITDDTQFWDLNAKLVEIPTKMRVERWAFNFSELIRDPKGRQSFQYFLK
KEFSGENLGFWEACEDLKYGDQSKVKEKAEEIYKLFLAPGARRWINIDGKTMDITVKGLKHPHRYVLDAAQTHIYMLMKKDSYARYLKSP
IYKDMLAKAIEPQETTKKSSTLPFMRRHLRSSPSPVILRQLEEEAKAREAANTVDITQPGQHMAPSPHLTVYTGTCMPPSPSSPFSSSCR
SPRKPFASPSRFIRRPSTTICPSPIRVALESSSGLEQKGECSGSMAPRGPSVTESSEASLDTSWPRSRPRAPPKARMALSFSRFLRRGCL

--------------------------------------------------------------

>10101_10101_24_BPTF-RGS9_BPTF_chr17_65850878_ENST00000321892_RGS9_chr17_63164318_ENST00000449996_length(amino acids)=983AA_BP=6
MRGRRGRPPKQPAAPAAERCAPAPPPPPPPPTSGPIGGLRSRHRGSSRGRWAAAQAEVAPKTRLSSPRGGSSSRRKPPPPPPAPPSTSAP
GRGGRGGGGGRTGGGGGGGHLARTTAARRAVNKVVYDDHESEEEEEEEDMVSEEEEEEDGDAEETQDSEDDEEDEMEEDDDDSDYPEEME
DDDDDASYCTESSFRSHSTYSSTPGRRKPRVHRPRSPILEEKDIPPLEFPKSSEDLMVPNEHIMNVIAIYEVLRNFGTVLRLSPFRFEDF
CAALVSQEQCTLMAEMHVVLLKAVLREEDTSNTTFGPADLKDSVNSTLYFIDGMTWPEVLRVYCESDKEYHHVLPYQEAEDYPYGPVENK
IKVLQFLVDQFLTTNIAREELMSEGVIQYDDHCRVCHKLGDLLCCETCSAVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVTDCVAEIQ
KNKPYIRHEPIGYDRSRRKYWFLNRRLIMAGKERNKADRYALDCQEKAYWLVHRCPPGMDNVLDYGLDRVTNPNEVKKQTVVAVKKEIMY
YQQALMRSTVKSSVSLGGIVKYSEQFSSNDAIMSGCLPSNPWITDDTQFWDLNAKLVEIPTKMRVERWAFNFSELIRDPKGRQSFQYFLK
KEFSGENLGFWEACEDLKYGDQSKVKEKAEEIYKLFLAPGARRWINIDGKTMDITVKGLKHPHRYVLDAAQTHIYMLMKKDSYARYLKSP
IYKDMLAKAIEPQETTKKSSTLPFMRRHLRSSPSPVILRQLEEEAKAREAANTVDITQPGQHMAPSPHLTVYTGTCMPPSPSSPFSSSCR
SPRKPFASPSRFIRRPSTTICPSPIRVALESSSGLEQKGECSGSMAPRGPSVTESSEASLDTSWPRSRPRAPPKARMALSFSRFLRRGCL

--------------------------------------------------------------

>10101_10101_25_BPTF-RGS9_BPTF_chr17_65850878_ENST00000335221_RGS9_chr17_63164317_ENST00000262406_length(amino acids)=986AA_BP=6
MRGRRGRPPKQPAAPAAERCAPAPPPPPPPPTSGPIGGLRSRHRGSSRGRWAAAQAEVAPKTRLSSPRGGSSSRRKPPPPPPAPPSTSAP
GRGGRGGGGGRTGGGGGGGHLARTTAARRAVNKVVYDDHESEEEEEEEDMVSEEEEEEDGDAEETQDSEDDEEDEMEEDDDDSDYPEEME
DDDDDASYCTESSFRSHSTYSSTPGRRKPRVHRPRSPILEEKDIPPLEFPKSSEDLMVPNEHIMNVIAIYEVLRNFGTVLRLSPFRFEDF
CAALVSQEQCTLMAEMHVVLLKAVLREEDTSNTTFGPADLKDSVNSTLYFIDGMTWPEVLRVYCESDKEYHHVLPYQEAEDYPYGPVENK
IKVLQFLVDQFLTTNIAREELMSEGVIQYDDHCRVCHKLGDLLCCETCSAVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVTDCVAEIQ
KNKPYIRHEPIGYDRSRRKYWFLNRRLIMAGKERNKADRYALDCQEKAYWLVHRCPPGMDNVLDYGLDRVTNPNEVKVNQKQTVVAVKKE
IMYYQQALMRSTVKSSVSLGGIVKYSEQFSSNDAIMSGCLPSNPWITDDTQFWDLNAKLVEIPTKMRVERWAFNFSELIRDPKGRQSFQY
FLKKEFSGENLGFWEACEDLKYGDQSKVKEKAEEIYKLFLAPGARRWINIDGKTMDITVKGLKHPHRYVLDAAQTHIYMLMKKDSYARYL
KSPIYKDMLAKAIEPQETTKKSSTLPFMRRHLRSSPSPVILRQLEEEAKAREAANTVDITQPGQHMAPSPHLTVYTGTCMPPSPSSPFSS
SCRSPRKPFASPSRFIRRPSTTICPSPIRVALESSSGLEQKGECSGSMAPRGPSVTESSEASLDTSWPRSRPRAPPKARMALSFSRFLRR

--------------------------------------------------------------

>10101_10101_26_BPTF-RGS9_BPTF_chr17_65850878_ENST00000335221_RGS9_chr17_63164317_ENST00000443584_length(amino acids)=940AA_BP=6
MRGRRGRPPKQPAAPAAERCAPAPPPPPPPPTSGPIGGLRSRHRGSSRGRWAAAQAEVAPKTRLSSPRGGSSSRRKPPPPPPAPPSTSAP
GRGGRGGGGGRTGGGGGGGHLARTTAARRAVNKVVYDDHESEEEEEEEDMVSEEEEEEDGDAEETQDSEDDEEDEMEEDDDDSDYPEEME
DDDDDASYCTESSFRSHSTYSSTPGRRKPRVHRPRSPILEEKDIPPLEFPKSSEDLMVPNEHIMNVIAIYEVLRNFGTVLRLSPFRFEDF
CAALVSQEQCTLMAEMHVVLLKAVLREEDTSNTTFGPADLKDSVNSTLYFIDGMTWPEVLRVYCESDKEYHHVLPYQEAEDYPYGPVENK
IKVLQFLVDQFLTTNIAREELMSEGVIQYDDHCRVCHKLGDLLCCETCSAVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVTDCVAEIQ
KNKPYIRHEPIGYDRSRRKYWFLNRRLIMAGKERNKADRYALDCQEKAYWLVHRCPPGMDNVLDYGLDRVTNPNEVKKQTVVAVKKEIMY
YQQALMRSTVKSSVSLGGIVKYSEQFSSNDAIMSGCLPSNPWITDDTQFWDLNAKLVEIPTKMRVERWAFNFSELIRDPKGRQSFQYFLK
KEFSGENLGFWEACEDLKYGDQSKVKEKAEEIYKLFLAPGARRWINIDGKTMDITVKGLKHPHRYVLDAAQTHIYMLMKKDSYARYLKSP
IYKDMLAKAIEPQETTKKSSTLPFMRRHLRSSPSPVILRQLEEEAKAREAANTVDITQPGQHMAPSPHLTVYTGTCMPPSPSSPFSSSCR
SPRKPFASPSRFIRRPSTTICPSPIRVALESSSGLEQKGECSGSMAPRGPSVTESSEASLDTSWPRSRPRAPPKARMALSFSRFLRRGCL

--------------------------------------------------------------

>10101_10101_27_BPTF-RGS9_BPTF_chr17_65850878_ENST00000335221_RGS9_chr17_63164317_ENST00000449996_length(amino acids)=983AA_BP=6
MRGRRGRPPKQPAAPAAERCAPAPPPPPPPPTSGPIGGLRSRHRGSSRGRWAAAQAEVAPKTRLSSPRGGSSSRRKPPPPPPAPPSTSAP
GRGGRGGGGGRTGGGGGGGHLARTTAARRAVNKVVYDDHESEEEEEEEDMVSEEEEEEDGDAEETQDSEDDEEDEMEEDDDDSDYPEEME
DDDDDASYCTESSFRSHSTYSSTPGRRKPRVHRPRSPILEEKDIPPLEFPKSSEDLMVPNEHIMNVIAIYEVLRNFGTVLRLSPFRFEDF
CAALVSQEQCTLMAEMHVVLLKAVLREEDTSNTTFGPADLKDSVNSTLYFIDGMTWPEVLRVYCESDKEYHHVLPYQEAEDYPYGPVENK
IKVLQFLVDQFLTTNIAREELMSEGVIQYDDHCRVCHKLGDLLCCETCSAVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVTDCVAEIQ
KNKPYIRHEPIGYDRSRRKYWFLNRRLIMAGKERNKADRYALDCQEKAYWLVHRCPPGMDNVLDYGLDRVTNPNEVKKQTVVAVKKEIMY
YQQALMRSTVKSSVSLGGIVKYSEQFSSNDAIMSGCLPSNPWITDDTQFWDLNAKLVEIPTKMRVERWAFNFSELIRDPKGRQSFQYFLK
KEFSGENLGFWEACEDLKYGDQSKVKEKAEEIYKLFLAPGARRWINIDGKTMDITVKGLKHPHRYVLDAAQTHIYMLMKKDSYARYLKSP
IYKDMLAKAIEPQETTKKSSTLPFMRRHLRSSPSPVILRQLEEEAKAREAANTVDITQPGQHMAPSPHLTVYTGTCMPPSPSSPFSSSCR
SPRKPFASPSRFIRRPSTTICPSPIRVALESSSGLEQKGECSGSMAPRGPSVTESSEASLDTSWPRSRPRAPPKARMALSFSRFLRRGCL

--------------------------------------------------------------

>10101_10101_28_BPTF-RGS9_BPTF_chr17_65850878_ENST00000335221_RGS9_chr17_63164318_ENST00000262406_length(amino acids)=986AA_BP=6
MRGRRGRPPKQPAAPAAERCAPAPPPPPPPPTSGPIGGLRSRHRGSSRGRWAAAQAEVAPKTRLSSPRGGSSSRRKPPPPPPAPPSTSAP
GRGGRGGGGGRTGGGGGGGHLARTTAARRAVNKVVYDDHESEEEEEEEDMVSEEEEEEDGDAEETQDSEDDEEDEMEEDDDDSDYPEEME
DDDDDASYCTESSFRSHSTYSSTPGRRKPRVHRPRSPILEEKDIPPLEFPKSSEDLMVPNEHIMNVIAIYEVLRNFGTVLRLSPFRFEDF
CAALVSQEQCTLMAEMHVVLLKAVLREEDTSNTTFGPADLKDSVNSTLYFIDGMTWPEVLRVYCESDKEYHHVLPYQEAEDYPYGPVENK
IKVLQFLVDQFLTTNIAREELMSEGVIQYDDHCRVCHKLGDLLCCETCSAVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVTDCVAEIQ
KNKPYIRHEPIGYDRSRRKYWFLNRRLIMAGKERNKADRYALDCQEKAYWLVHRCPPGMDNVLDYGLDRVTNPNEVKVNQKQTVVAVKKE
IMYYQQALMRSTVKSSVSLGGIVKYSEQFSSNDAIMSGCLPSNPWITDDTQFWDLNAKLVEIPTKMRVERWAFNFSELIRDPKGRQSFQY
FLKKEFSGENLGFWEACEDLKYGDQSKVKEKAEEIYKLFLAPGARRWINIDGKTMDITVKGLKHPHRYVLDAAQTHIYMLMKKDSYARYL
KSPIYKDMLAKAIEPQETTKKSSTLPFMRRHLRSSPSPVILRQLEEEAKAREAANTVDITQPGQHMAPSPHLTVYTGTCMPPSPSSPFSS
SCRSPRKPFASPSRFIRRPSTTICPSPIRVALESSSGLEQKGECSGSMAPRGPSVTESSEASLDTSWPRSRPRAPPKARMALSFSRFLRR

--------------------------------------------------------------

>10101_10101_29_BPTF-RGS9_BPTF_chr17_65850878_ENST00000335221_RGS9_chr17_63164318_ENST00000443584_length(amino acids)=940AA_BP=6
MRGRRGRPPKQPAAPAAERCAPAPPPPPPPPTSGPIGGLRSRHRGSSRGRWAAAQAEVAPKTRLSSPRGGSSSRRKPPPPPPAPPSTSAP
GRGGRGGGGGRTGGGGGGGHLARTTAARRAVNKVVYDDHESEEEEEEEDMVSEEEEEEDGDAEETQDSEDDEEDEMEEDDDDSDYPEEME
DDDDDASYCTESSFRSHSTYSSTPGRRKPRVHRPRSPILEEKDIPPLEFPKSSEDLMVPNEHIMNVIAIYEVLRNFGTVLRLSPFRFEDF
CAALVSQEQCTLMAEMHVVLLKAVLREEDTSNTTFGPADLKDSVNSTLYFIDGMTWPEVLRVYCESDKEYHHVLPYQEAEDYPYGPVENK
IKVLQFLVDQFLTTNIAREELMSEGVIQYDDHCRVCHKLGDLLCCETCSAVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVTDCVAEIQ
KNKPYIRHEPIGYDRSRRKYWFLNRRLIMAGKERNKADRYALDCQEKAYWLVHRCPPGMDNVLDYGLDRVTNPNEVKKQTVVAVKKEIMY
YQQALMRSTVKSSVSLGGIVKYSEQFSSNDAIMSGCLPSNPWITDDTQFWDLNAKLVEIPTKMRVERWAFNFSELIRDPKGRQSFQYFLK
KEFSGENLGFWEACEDLKYGDQSKVKEKAEEIYKLFLAPGARRWINIDGKTMDITVKGLKHPHRYVLDAAQTHIYMLMKKDSYARYLKSP
IYKDMLAKAIEPQETTKKSSTLPFMRRHLRSSPSPVILRQLEEEAKAREAANTVDITQPGQHMAPSPHLTVYTGTCMPPSPSSPFSSSCR
SPRKPFASPSRFIRRPSTTICPSPIRVALESSSGLEQKGECSGSMAPRGPSVTESSEASLDTSWPRSRPRAPPKARMALSFSRFLRRGCL

--------------------------------------------------------------

>10101_10101_30_BPTF-RGS9_BPTF_chr17_65850878_ENST00000335221_RGS9_chr17_63164318_ENST00000449996_length(amino acids)=983AA_BP=6
MRGRRGRPPKQPAAPAAERCAPAPPPPPPPPTSGPIGGLRSRHRGSSRGRWAAAQAEVAPKTRLSSPRGGSSSRRKPPPPPPAPPSTSAP
GRGGRGGGGGRTGGGGGGGHLARTTAARRAVNKVVYDDHESEEEEEEEDMVSEEEEEEDGDAEETQDSEDDEEDEMEEDDDDSDYPEEME
DDDDDASYCTESSFRSHSTYSSTPGRRKPRVHRPRSPILEEKDIPPLEFPKSSEDLMVPNEHIMNVIAIYEVLRNFGTVLRLSPFRFEDF
CAALVSQEQCTLMAEMHVVLLKAVLREEDTSNTTFGPADLKDSVNSTLYFIDGMTWPEVLRVYCESDKEYHHVLPYQEAEDYPYGPVENK
IKVLQFLVDQFLTTNIAREELMSEGVIQYDDHCRVCHKLGDLLCCETCSAVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVTDCVAEIQ
KNKPYIRHEPIGYDRSRRKYWFLNRRLIMAGKERNKADRYALDCQEKAYWLVHRCPPGMDNVLDYGLDRVTNPNEVKKQTVVAVKKEIMY
YQQALMRSTVKSSVSLGGIVKYSEQFSSNDAIMSGCLPSNPWITDDTQFWDLNAKLVEIPTKMRVERWAFNFSELIRDPKGRQSFQYFLK
KEFSGENLGFWEACEDLKYGDQSKVKEKAEEIYKLFLAPGARRWINIDGKTMDITVKGLKHPHRYVLDAAQTHIYMLMKKDSYARYLKSP
IYKDMLAKAIEPQETTKKSSTLPFMRRHLRSSPSPVILRQLEEEAKAREAANTVDITQPGQHMAPSPHLTVYTGTCMPPSPSSPFSSSCR
SPRKPFASPSRFIRRPSTTICPSPIRVALESSSGLEQKGECSGSMAPRGPSVTESSEASLDTSWPRSRPRAPPKARMALSFSRFLRRGCL

--------------------------------------------------------------

>10101_10101_31_BPTF-RGS9_BPTF_chr17_65850878_ENST00000424123_RGS9_chr17_63164317_ENST00000262406_length(amino acids)=847AA_BP=340
MVSEEEEEEDGDAEETQDSEDDEEDEMEEDDDDSDYPEEMEDDDDDASYCTESSFRSHSTYSSTPGRRKPRVHRPRSPILEEKDIPPLEF
PKSSEDLMVPNEHIMNVIAIYEVLRNFGTVLRLSPFRFEDFCAALVSQEQCTLMAEMHVVLLKAVLREEDTSNTTFGPADLKDSVNSTLY
FIDGMTWPEVLRVYCESDKEYHHVLPYQEAEDYPYGPVENKIKVLQFLVDQFLTTNIAREELMSEGVIQYDDHCRVCHKLGDLLCCETCS
AVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVTDCVAEIQKNKPYIRHEPIGYDRSRRKYWFLNRRLIMAGKERNKADRYALDCQEKAY
WLVHRCPPGMDNVLDYGLDRVTNPNEVKVNQKQTVVAVKKEIMYYQQALMRSTVKSSVSLGGIVKYSEQFSSNDAIMSGCLPSNPWITDD
TQFWDLNAKLVEIPTKMRVERWAFNFSELIRDPKGRQSFQYFLKKEFSGENLGFWEACEDLKYGDQSKVKEKAEEIYKLFLAPGARRWIN
IDGKTMDITVKGLKHPHRYVLDAAQTHIYMLMKKDSYARYLKSPIYKDMLAKAIEPQETTKKSSTLPFMRRHLRSSPSPVILRQLEEEAK
AREAANTVDITQPGQHMAPSPHLTVYTGTCMPPSPSSPFSSSCRSPRKPFASPSRFIRRPSTTICPSPIRVALESSSGLEQKGECSGSMA
PRGPSVTESSEASLDTSWPRSRPRAPPKARMALSFSRFLRRGCLASPVFARLSPKCPAVSHGRVQPLGDVGQQLPRLKSKRVANFFQIKM

--------------------------------------------------------------

>10101_10101_32_BPTF-RGS9_BPTF_chr17_65850878_ENST00000424123_RGS9_chr17_63164317_ENST00000443584_length(amino acids)=801AA_BP=340
MVSEEEEEEDGDAEETQDSEDDEEDEMEEDDDDSDYPEEMEDDDDDASYCTESSFRSHSTYSSTPGRRKPRVHRPRSPILEEKDIPPLEF
PKSSEDLMVPNEHIMNVIAIYEVLRNFGTVLRLSPFRFEDFCAALVSQEQCTLMAEMHVVLLKAVLREEDTSNTTFGPADLKDSVNSTLY
FIDGMTWPEVLRVYCESDKEYHHVLPYQEAEDYPYGPVENKIKVLQFLVDQFLTTNIAREELMSEGVIQYDDHCRVCHKLGDLLCCETCS
AVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVTDCVAEIQKNKPYIRHEPIGYDRSRRKYWFLNRRLIMAGKERNKADRYALDCQEKAY
WLVHRCPPGMDNVLDYGLDRVTNPNEVKKQTVVAVKKEIMYYQQALMRSTVKSSVSLGGIVKYSEQFSSNDAIMSGCLPSNPWITDDTQF
WDLNAKLVEIPTKMRVERWAFNFSELIRDPKGRQSFQYFLKKEFSGENLGFWEACEDLKYGDQSKVKEKAEEIYKLFLAPGARRWINIDG
KTMDITVKGLKHPHRYVLDAAQTHIYMLMKKDSYARYLKSPIYKDMLAKAIEPQETTKKSSTLPFMRRHLRSSPSPVILRQLEEEAKARE
AANTVDITQPGQHMAPSPHLTVYTGTCMPPSPSSPFSSSCRSPRKPFASPSRFIRRPSTTICPSPIRVALESSSGLEQKGECSGSMAPRG

--------------------------------------------------------------

>10101_10101_33_BPTF-RGS9_BPTF_chr17_65850878_ENST00000424123_RGS9_chr17_63164317_ENST00000449996_length(amino acids)=844AA_BP=340
MVSEEEEEEDGDAEETQDSEDDEEDEMEEDDDDSDYPEEMEDDDDDASYCTESSFRSHSTYSSTPGRRKPRVHRPRSPILEEKDIPPLEF
PKSSEDLMVPNEHIMNVIAIYEVLRNFGTVLRLSPFRFEDFCAALVSQEQCTLMAEMHVVLLKAVLREEDTSNTTFGPADLKDSVNSTLY
FIDGMTWPEVLRVYCESDKEYHHVLPYQEAEDYPYGPVENKIKVLQFLVDQFLTTNIAREELMSEGVIQYDDHCRVCHKLGDLLCCETCS
AVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVTDCVAEIQKNKPYIRHEPIGYDRSRRKYWFLNRRLIMAGKERNKADRYALDCQEKAY
WLVHRCPPGMDNVLDYGLDRVTNPNEVKKQTVVAVKKEIMYYQQALMRSTVKSSVSLGGIVKYSEQFSSNDAIMSGCLPSNPWITDDTQF
WDLNAKLVEIPTKMRVERWAFNFSELIRDPKGRQSFQYFLKKEFSGENLGFWEACEDLKYGDQSKVKEKAEEIYKLFLAPGARRWINIDG
KTMDITVKGLKHPHRYVLDAAQTHIYMLMKKDSYARYLKSPIYKDMLAKAIEPQETTKKSSTLPFMRRHLRSSPSPVILRQLEEEAKARE
AANTVDITQPGQHMAPSPHLTVYTGTCMPPSPSSPFSSSCRSPRKPFASPSRFIRRPSTTICPSPIRVALESSSGLEQKGECSGSMAPRG
PSVTESSEASLDTSWPRSRPRAPPKARMALSFSRFLRRGCLASPVFARLSPKCPAVSHGRVQPLGDVGQQLPRLKSKRVANFFQIKMDVP

--------------------------------------------------------------

>10101_10101_34_BPTF-RGS9_BPTF_chr17_65850878_ENST00000424123_RGS9_chr17_63164318_ENST00000262406_length(amino acids)=847AA_BP=340
MVSEEEEEEDGDAEETQDSEDDEEDEMEEDDDDSDYPEEMEDDDDDASYCTESSFRSHSTYSSTPGRRKPRVHRPRSPILEEKDIPPLEF
PKSSEDLMVPNEHIMNVIAIYEVLRNFGTVLRLSPFRFEDFCAALVSQEQCTLMAEMHVVLLKAVLREEDTSNTTFGPADLKDSVNSTLY
FIDGMTWPEVLRVYCESDKEYHHVLPYQEAEDYPYGPVENKIKVLQFLVDQFLTTNIAREELMSEGVIQYDDHCRVCHKLGDLLCCETCS
AVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVTDCVAEIQKNKPYIRHEPIGYDRSRRKYWFLNRRLIMAGKERNKADRYALDCQEKAY
WLVHRCPPGMDNVLDYGLDRVTNPNEVKVNQKQTVVAVKKEIMYYQQALMRSTVKSSVSLGGIVKYSEQFSSNDAIMSGCLPSNPWITDD
TQFWDLNAKLVEIPTKMRVERWAFNFSELIRDPKGRQSFQYFLKKEFSGENLGFWEACEDLKYGDQSKVKEKAEEIYKLFLAPGARRWIN
IDGKTMDITVKGLKHPHRYVLDAAQTHIYMLMKKDSYARYLKSPIYKDMLAKAIEPQETTKKSSTLPFMRRHLRSSPSPVILRQLEEEAK
AREAANTVDITQPGQHMAPSPHLTVYTGTCMPPSPSSPFSSSCRSPRKPFASPSRFIRRPSTTICPSPIRVALESSSGLEQKGECSGSMA
PRGPSVTESSEASLDTSWPRSRPRAPPKARMALSFSRFLRRGCLASPVFARLSPKCPAVSHGRVQPLGDVGQQLPRLKSKRVANFFQIKM

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>10101_10101_35_BPTF-RGS9_BPTF_chr17_65850878_ENST00000424123_RGS9_chr17_63164318_ENST00000443584_length(amino acids)=801AA_BP=340
MVSEEEEEEDGDAEETQDSEDDEEDEMEEDDDDSDYPEEMEDDDDDASYCTESSFRSHSTYSSTPGRRKPRVHRPRSPILEEKDIPPLEF
PKSSEDLMVPNEHIMNVIAIYEVLRNFGTVLRLSPFRFEDFCAALVSQEQCTLMAEMHVVLLKAVLREEDTSNTTFGPADLKDSVNSTLY
FIDGMTWPEVLRVYCESDKEYHHVLPYQEAEDYPYGPVENKIKVLQFLVDQFLTTNIAREELMSEGVIQYDDHCRVCHKLGDLLCCETCS
AVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVTDCVAEIQKNKPYIRHEPIGYDRSRRKYWFLNRRLIMAGKERNKADRYALDCQEKAY
WLVHRCPPGMDNVLDYGLDRVTNPNEVKKQTVVAVKKEIMYYQQALMRSTVKSSVSLGGIVKYSEQFSSNDAIMSGCLPSNPWITDDTQF
WDLNAKLVEIPTKMRVERWAFNFSELIRDPKGRQSFQYFLKKEFSGENLGFWEACEDLKYGDQSKVKEKAEEIYKLFLAPGARRWINIDG
KTMDITVKGLKHPHRYVLDAAQTHIYMLMKKDSYARYLKSPIYKDMLAKAIEPQETTKKSSTLPFMRRHLRSSPSPVILRQLEEEAKARE
AANTVDITQPGQHMAPSPHLTVYTGTCMPPSPSSPFSSSCRSPRKPFASPSRFIRRPSTTICPSPIRVALESSSGLEQKGECSGSMAPRG

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>10101_10101_36_BPTF-RGS9_BPTF_chr17_65850878_ENST00000424123_RGS9_chr17_63164318_ENST00000449996_length(amino acids)=844AA_BP=340
MVSEEEEEEDGDAEETQDSEDDEEDEMEEDDDDSDYPEEMEDDDDDASYCTESSFRSHSTYSSTPGRRKPRVHRPRSPILEEKDIPPLEF
PKSSEDLMVPNEHIMNVIAIYEVLRNFGTVLRLSPFRFEDFCAALVSQEQCTLMAEMHVVLLKAVLREEDTSNTTFGPADLKDSVNSTLY
FIDGMTWPEVLRVYCESDKEYHHVLPYQEAEDYPYGPVENKIKVLQFLVDQFLTTNIAREELMSEGVIQYDDHCRVCHKLGDLLCCETCS
AVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVTDCVAEIQKNKPYIRHEPIGYDRSRRKYWFLNRRLIMAGKERNKADRYALDCQEKAY
WLVHRCPPGMDNVLDYGLDRVTNPNEVKKQTVVAVKKEIMYYQQALMRSTVKSSVSLGGIVKYSEQFSSNDAIMSGCLPSNPWITDDTQF
WDLNAKLVEIPTKMRVERWAFNFSELIRDPKGRQSFQYFLKKEFSGENLGFWEACEDLKYGDQSKVKEKAEEIYKLFLAPGARRWINIDG
KTMDITVKGLKHPHRYVLDAAQTHIYMLMKKDSYARYLKSPIYKDMLAKAIEPQETTKKSSTLPFMRRHLRSSPSPVILRQLEEEAKARE
AANTVDITQPGQHMAPSPHLTVYTGTCMPPSPSSPFSSSCRSPRKPFASPSRFIRRPSTTICPSPIRVALESSSGLEQKGECSGSMAPRG
PSVTESSEASLDTSWPRSRPRAPPKARMALSFSRFLRRGCLASPVFARLSPKCPAVSHGRVQPLGDVGQQLPRLKSKRVANFFQIKMDVP

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Fusion Protein Functional Features


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr17:65850878/chr17:63164318)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
BPTF

Q12830

.
FUNCTION: Histone-binding component of NURF (nucleosome-remodeling factor), a complex which catalyzes ATP-dependent nucleosome sliding and facilitates transcription of chromatin. Specifically recognizes H3 tails trimethylated on 'Lys-4' (H3K4me3), which mark transcription start sites of virtually all active genes. May also regulate transcription through direct binding to DNA or transcription factors.FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

* Minus value of BPloci means that the break pointn is located before the CDS.
- Retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneBPTFchr17:65850877chr17:63164317ENST00000306378+228143_180478.66666666666672921.0Compositional biasNote=Glu-rich
HgeneBPTFchr17:65850877chr17:63164317ENST00000306378+228149_185478.66666666666672921.0Compositional biasNote=Asp-rich
HgeneBPTFchr17:65850877chr17:63164317ENST00000321892+230143_180478.66666666666673047.0Compositional biasNote=Glu-rich
HgeneBPTFchr17:65850877chr17:63164317ENST00000321892+230149_185478.66666666666673047.0Compositional biasNote=Asp-rich
HgeneBPTFchr17:65850877chr17:63164317ENST00000335221+230143_180478.66666666666672904.0Compositional biasNote=Glu-rich
HgeneBPTFchr17:65850877chr17:63164317ENST00000335221+230149_185478.66666666666672904.0Compositional biasNote=Asp-rich
HgeneBPTFchr17:65850878chr17:63164317ENST00000306378+228143_180478.66666666666672921.0Compositional biasNote=Glu-rich
HgeneBPTFchr17:65850878chr17:63164317ENST00000306378+228149_185478.66666666666672921.0Compositional biasNote=Asp-rich
HgeneBPTFchr17:65850878chr17:63164317ENST00000321892+230143_180478.66666666666673047.0Compositional biasNote=Glu-rich
HgeneBPTFchr17:65850878chr17:63164317ENST00000321892+230149_185478.66666666666673047.0Compositional biasNote=Asp-rich
HgeneBPTFchr17:65850878chr17:63164317ENST00000335221+230143_180478.66666666666672904.0Compositional biasNote=Glu-rich
HgeneBPTFchr17:65850878chr17:63164317ENST00000335221+230149_185478.66666666666672904.0Compositional biasNote=Asp-rich
HgeneBPTFchr17:65850878chr17:63164318ENST00000306378+228143_180478.66666666666672921.0Compositional biasNote=Glu-rich
HgeneBPTFchr17:65850878chr17:63164318ENST00000306378+228149_185478.66666666666672921.0Compositional biasNote=Asp-rich
HgeneBPTFchr17:65850878chr17:63164318ENST00000321892+230143_180478.66666666666673047.0Compositional biasNote=Glu-rich
HgeneBPTFchr17:65850878chr17:63164318ENST00000321892+230149_185478.66666666666673047.0Compositional biasNote=Asp-rich
HgeneBPTFchr17:65850878chr17:63164318ENST00000335221+230143_180478.66666666666672904.0Compositional biasNote=Glu-rich
HgeneBPTFchr17:65850878chr17:63164318ENST00000335221+230149_185478.66666666666672904.0Compositional biasNote=Asp-rich
HgeneBPTFchr17:65850877chr17:63164317ENST00000306378+228240_300478.66666666666672921.0DomainDDT
HgeneBPTFchr17:65850877chr17:63164317ENST00000321892+230240_300478.66666666666673047.0DomainDDT
HgeneBPTFchr17:65850877chr17:63164317ENST00000335221+230240_300478.66666666666672904.0DomainDDT
HgeneBPTFchr17:65850878chr17:63164317ENST00000306378+228240_300478.66666666666672921.0DomainDDT
HgeneBPTFchr17:65850878chr17:63164317ENST00000321892+230240_300478.66666666666673047.0DomainDDT
HgeneBPTFchr17:65850878chr17:63164317ENST00000335221+230240_300478.66666666666672904.0DomainDDT
HgeneBPTFchr17:65850878chr17:63164318ENST00000306378+228240_300478.66666666666672921.0DomainDDT
HgeneBPTFchr17:65850878chr17:63164318ENST00000321892+230240_300478.66666666666673047.0DomainDDT
HgeneBPTFchr17:65850878chr17:63164318ENST00000335221+230240_300478.66666666666672904.0DomainDDT
HgeneBPTFchr17:65850877chr17:63164317ENST00000306378+228390_437478.66666666666672921.0Zinc fingerPHD-type 1
HgeneBPTFchr17:65850877chr17:63164317ENST00000321892+230390_437478.66666666666673047.0Zinc fingerPHD-type 1
HgeneBPTFchr17:65850877chr17:63164317ENST00000335221+230390_437478.66666666666672904.0Zinc fingerPHD-type 1
HgeneBPTFchr17:65850878chr17:63164317ENST00000306378+228390_437478.66666666666672921.0Zinc fingerPHD-type 1
HgeneBPTFchr17:65850878chr17:63164317ENST00000321892+230390_437478.66666666666673047.0Zinc fingerPHD-type 1
HgeneBPTFchr17:65850878chr17:63164317ENST00000335221+230390_437478.66666666666672904.0Zinc fingerPHD-type 1
HgeneBPTFchr17:65850878chr17:63164318ENST00000306378+228390_437478.66666666666672921.0Zinc fingerPHD-type 1
HgeneBPTFchr17:65850878chr17:63164318ENST00000321892+230390_437478.66666666666673047.0Zinc fingerPHD-type 1
HgeneBPTFchr17:65850878chr17:63164318ENST00000335221+230390_437478.66666666666672904.0Zinc fingerPHD-type 1
TgeneRGS9chr17:65850877chr17:63164317ENST00000262406619219_280166.66666666666666675.0DomainNote=G protein gamma
TgeneRGS9chr17:65850877chr17:63164317ENST00000262406619298_413166.66666666666666675.0DomainRGS
TgeneRGS9chr17:65850877chr17:63164317ENST00000449996619219_280166.66666666666666672.0DomainNote=G protein gamma
TgeneRGS9chr17:65850877chr17:63164317ENST00000449996619298_413166.66666666666666672.0DomainRGS
TgeneRGS9chr17:65850878chr17:63164317ENST00000262406619219_280166.66666666666666675.0DomainNote=G protein gamma
TgeneRGS9chr17:65850878chr17:63164317ENST00000262406619298_413166.66666666666666675.0DomainRGS
TgeneRGS9chr17:65850878chr17:63164317ENST00000449996619219_280166.66666666666666672.0DomainNote=G protein gamma
TgeneRGS9chr17:65850878chr17:63164317ENST00000449996619298_413166.66666666666666672.0DomainRGS
TgeneRGS9chr17:65850878chr17:63164318ENST00000262406619219_280166.66666666666666675.0DomainNote=G protein gamma
TgeneRGS9chr17:65850878chr17:63164318ENST00000262406619298_413166.66666666666666675.0DomainRGS
TgeneRGS9chr17:65850878chr17:63164318ENST00000449996619219_280166.66666666666666672.0DomainNote=G protein gamma
TgeneRGS9chr17:65850878chr17:63164318ENST00000449996619298_413166.66666666666666672.0DomainRGS

- Not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneBPTFchr17:65850877chr17:63164317ENST00000306378+2282022_2050478.66666666666672921.0Coiled coilOntology_term=ECO:0000255
HgeneBPTFchr17:65850877chr17:63164317ENST00000306378+2282706_2732478.66666666666672921.0Coiled coilOntology_term=ECO:0000255
HgeneBPTFchr17:65850877chr17:63164317ENST00000306378+228574_604478.66666666666672921.0Coiled coilOntology_term=ECO:0000255
HgeneBPTFchr17:65850877chr17:63164317ENST00000306378+228978_1007478.66666666666672921.0Coiled coilOntology_term=ECO:0000255
HgeneBPTFchr17:65850877chr17:63164317ENST00000321892+2302022_2050478.66666666666673047.0Coiled coilOntology_term=ECO:0000255
HgeneBPTFchr17:65850877chr17:63164317ENST00000321892+2302706_2732478.66666666666673047.0Coiled coilOntology_term=ECO:0000255
HgeneBPTFchr17:65850877chr17:63164317ENST00000321892+230574_604478.66666666666673047.0Coiled coilOntology_term=ECO:0000255
HgeneBPTFchr17:65850877chr17:63164317ENST00000321892+230978_1007478.66666666666673047.0Coiled coilOntology_term=ECO:0000255
HgeneBPTFchr17:65850877chr17:63164317ENST00000335221+2302022_2050478.66666666666672904.0Coiled coilOntology_term=ECO:0000255
HgeneBPTFchr17:65850877chr17:63164317ENST00000335221+2302706_2732478.66666666666672904.0Coiled coilOntology_term=ECO:0000255
HgeneBPTFchr17:65850877chr17:63164317ENST00000335221+230574_604478.66666666666672904.0Coiled coilOntology_term=ECO:0000255
HgeneBPTFchr17:65850877chr17:63164317ENST00000335221+230978_1007478.66666666666672904.0Coiled coilOntology_term=ECO:0000255
HgeneBPTFchr17:65850878chr17:63164317ENST00000306378+2282022_2050478.66666666666672921.0Coiled coilOntology_term=ECO:0000255
HgeneBPTFchr17:65850878chr17:63164317ENST00000306378+2282706_2732478.66666666666672921.0Coiled coilOntology_term=ECO:0000255
HgeneBPTFchr17:65850878chr17:63164317ENST00000306378+228574_604478.66666666666672921.0Coiled coilOntology_term=ECO:0000255
HgeneBPTFchr17:65850878chr17:63164317ENST00000306378+228978_1007478.66666666666672921.0Coiled coilOntology_term=ECO:0000255
HgeneBPTFchr17:65850878chr17:63164317ENST00000321892+2302022_2050478.66666666666673047.0Coiled coilOntology_term=ECO:0000255
HgeneBPTFchr17:65850878chr17:63164317ENST00000321892+2302706_2732478.66666666666673047.0Coiled coilOntology_term=ECO:0000255
HgeneBPTFchr17:65850878chr17:63164317ENST00000321892+230574_604478.66666666666673047.0Coiled coilOntology_term=ECO:0000255
HgeneBPTFchr17:65850878chr17:63164317ENST00000321892+230978_1007478.66666666666673047.0Coiled coilOntology_term=ECO:0000255
HgeneBPTFchr17:65850878chr17:63164317ENST00000335221+2302022_2050478.66666666666672904.0Coiled coilOntology_term=ECO:0000255
HgeneBPTFchr17:65850878chr17:63164317ENST00000335221+2302706_2732478.66666666666672904.0Coiled coilOntology_term=ECO:0000255
HgeneBPTFchr17:65850878chr17:63164317ENST00000335221+230574_604478.66666666666672904.0Coiled coilOntology_term=ECO:0000255
HgeneBPTFchr17:65850878chr17:63164317ENST00000335221+230978_1007478.66666666666672904.0Coiled coilOntology_term=ECO:0000255
HgeneBPTFchr17:65850878chr17:63164318ENST00000306378+2282022_2050478.66666666666672921.0Coiled coilOntology_term=ECO:0000255
HgeneBPTFchr17:65850878chr17:63164318ENST00000306378+2282706_2732478.66666666666672921.0Coiled coilOntology_term=ECO:0000255
HgeneBPTFchr17:65850878chr17:63164318ENST00000306378+228574_604478.66666666666672921.0Coiled coilOntology_term=ECO:0000255
HgeneBPTFchr17:65850878chr17:63164318ENST00000306378+228978_1007478.66666666666672921.0Coiled coilOntology_term=ECO:0000255
HgeneBPTFchr17:65850878chr17:63164318ENST00000321892+2302022_2050478.66666666666673047.0Coiled coilOntology_term=ECO:0000255
HgeneBPTFchr17:65850878chr17:63164318ENST00000321892+2302706_2732478.66666666666673047.0Coiled coilOntology_term=ECO:0000255
HgeneBPTFchr17:65850878chr17:63164318ENST00000321892+230574_604478.66666666666673047.0Coiled coilOntology_term=ECO:0000255
HgeneBPTFchr17:65850878chr17:63164318ENST00000321892+230978_1007478.66666666666673047.0Coiled coilOntology_term=ECO:0000255
HgeneBPTFchr17:65850878chr17:63164318ENST00000335221+2302022_2050478.66666666666672904.0Coiled coilOntology_term=ECO:0000255
HgeneBPTFchr17:65850878chr17:63164318ENST00000335221+2302706_2732478.66666666666672904.0Coiled coilOntology_term=ECO:0000255
HgeneBPTFchr17:65850878chr17:63164318ENST00000335221+230574_604478.66666666666672904.0Coiled coilOntology_term=ECO:0000255
HgeneBPTFchr17:65850878chr17:63164318ENST00000335221+230978_1007478.66666666666672904.0Coiled coilOntology_term=ECO:0000255
HgeneBPTFchr17:65850877chr17:63164317ENST00000306378+2281709_1803478.66666666666672921.0Compositional biasNote=Thr-rich
HgeneBPTFchr17:65850877chr17:63164317ENST00000306378+2282338_2361478.66666666666672921.0Compositional biasNote=Thr-rich
HgeneBPTFchr17:65850877chr17:63164317ENST00000306378+2282795_2817478.66666666666672921.0Compositional biasNote=Pro-rich
HgeneBPTFchr17:65850877chr17:63164317ENST00000306378+2282848_2853478.66666666666672921.0Compositional biasNote=Poly-Lys
HgeneBPTFchr17:65850877chr17:63164317ENST00000321892+2301709_1803478.66666666666673047.0Compositional biasNote=Thr-rich
HgeneBPTFchr17:65850877chr17:63164317ENST00000321892+2302338_2361478.66666666666673047.0Compositional biasNote=Thr-rich
HgeneBPTFchr17:65850877chr17:63164317ENST00000321892+2302795_2817478.66666666666673047.0Compositional biasNote=Pro-rich
HgeneBPTFchr17:65850877chr17:63164317ENST00000321892+2302848_2853478.66666666666673047.0Compositional biasNote=Poly-Lys
HgeneBPTFchr17:65850877chr17:63164317ENST00000335221+2301709_1803478.66666666666672904.0Compositional biasNote=Thr-rich
HgeneBPTFchr17:65850877chr17:63164317ENST00000335221+2302338_2361478.66666666666672904.0Compositional biasNote=Thr-rich
HgeneBPTFchr17:65850877chr17:63164317ENST00000335221+2302795_2817478.66666666666672904.0Compositional biasNote=Pro-rich
HgeneBPTFchr17:65850877chr17:63164317ENST00000335221+2302848_2853478.66666666666672904.0Compositional biasNote=Poly-Lys
HgeneBPTFchr17:65850878chr17:63164317ENST00000306378+2281709_1803478.66666666666672921.0Compositional biasNote=Thr-rich
HgeneBPTFchr17:65850878chr17:63164317ENST00000306378+2282338_2361478.66666666666672921.0Compositional biasNote=Thr-rich
HgeneBPTFchr17:65850878chr17:63164317ENST00000306378+2282795_2817478.66666666666672921.0Compositional biasNote=Pro-rich
HgeneBPTFchr17:65850878chr17:63164317ENST00000306378+2282848_2853478.66666666666672921.0Compositional biasNote=Poly-Lys
HgeneBPTFchr17:65850878chr17:63164317ENST00000321892+2301709_1803478.66666666666673047.0Compositional biasNote=Thr-rich
HgeneBPTFchr17:65850878chr17:63164317ENST00000321892+2302338_2361478.66666666666673047.0Compositional biasNote=Thr-rich
HgeneBPTFchr17:65850878chr17:63164317ENST00000321892+2302795_2817478.66666666666673047.0Compositional biasNote=Pro-rich
HgeneBPTFchr17:65850878chr17:63164317ENST00000321892+2302848_2853478.66666666666673047.0Compositional biasNote=Poly-Lys
HgeneBPTFchr17:65850878chr17:63164317ENST00000335221+2301709_1803478.66666666666672904.0Compositional biasNote=Thr-rich
HgeneBPTFchr17:65850878chr17:63164317ENST00000335221+2302338_2361478.66666666666672904.0Compositional biasNote=Thr-rich
HgeneBPTFchr17:65850878chr17:63164317ENST00000335221+2302795_2817478.66666666666672904.0Compositional biasNote=Pro-rich
HgeneBPTFchr17:65850878chr17:63164317ENST00000335221+2302848_2853478.66666666666672904.0Compositional biasNote=Poly-Lys
HgeneBPTFchr17:65850878chr17:63164318ENST00000306378+2281709_1803478.66666666666672921.0Compositional biasNote=Thr-rich
HgeneBPTFchr17:65850878chr17:63164318ENST00000306378+2282338_2361478.66666666666672921.0Compositional biasNote=Thr-rich
HgeneBPTFchr17:65850878chr17:63164318ENST00000306378+2282795_2817478.66666666666672921.0Compositional biasNote=Pro-rich
HgeneBPTFchr17:65850878chr17:63164318ENST00000306378+2282848_2853478.66666666666672921.0Compositional biasNote=Poly-Lys
HgeneBPTFchr17:65850878chr17:63164318ENST00000321892+2301709_1803478.66666666666673047.0Compositional biasNote=Thr-rich
HgeneBPTFchr17:65850878chr17:63164318ENST00000321892+2302338_2361478.66666666666673047.0Compositional biasNote=Thr-rich
HgeneBPTFchr17:65850878chr17:63164318ENST00000321892+2302795_2817478.66666666666673047.0Compositional biasNote=Pro-rich
HgeneBPTFchr17:65850878chr17:63164318ENST00000321892+2302848_2853478.66666666666673047.0Compositional biasNote=Poly-Lys
HgeneBPTFchr17:65850878chr17:63164318ENST00000335221+2301709_1803478.66666666666672904.0Compositional biasNote=Thr-rich
HgeneBPTFchr17:65850878chr17:63164318ENST00000335221+2302338_2361478.66666666666672904.0Compositional biasNote=Thr-rich
HgeneBPTFchr17:65850878chr17:63164318ENST00000335221+2302795_2817478.66666666666672904.0Compositional biasNote=Pro-rich
HgeneBPTFchr17:65850878chr17:63164318ENST00000335221+2302848_2853478.66666666666672904.0Compositional biasNote=Poly-Lys
HgeneBPTFchr17:65850877chr17:63164317ENST00000306378+2282944_3014478.66666666666672921.0DomainBromo
HgeneBPTFchr17:65850877chr17:63164317ENST00000321892+2302944_3014478.66666666666673047.0DomainBromo
HgeneBPTFchr17:65850877chr17:63164317ENST00000335221+2302944_3014478.66666666666672904.0DomainBromo
HgeneBPTFchr17:65850878chr17:63164317ENST00000306378+2282944_3014478.66666666666672921.0DomainBromo
HgeneBPTFchr17:65850878chr17:63164317ENST00000321892+2302944_3014478.66666666666673047.0DomainBromo
HgeneBPTFchr17:65850878chr17:63164317ENST00000335221+2302944_3014478.66666666666672904.0DomainBromo
HgeneBPTFchr17:65850878chr17:63164318ENST00000306378+2282944_3014478.66666666666672921.0DomainBromo
HgeneBPTFchr17:65850878chr17:63164318ENST00000321892+2302944_3014478.66666666666673047.0DomainBromo
HgeneBPTFchr17:65850878chr17:63164318ENST00000335221+2302944_3014478.66666666666672904.0DomainBromo
HgeneBPTFchr17:65850877chr17:63164317ENST00000306378+2282867_2918478.66666666666672921.0Zinc fingerPHD-type 2
HgeneBPTFchr17:65850877chr17:63164317ENST00000321892+2302867_2918478.66666666666673047.0Zinc fingerPHD-type 2
HgeneBPTFchr17:65850877chr17:63164317ENST00000335221+2302867_2918478.66666666666672904.0Zinc fingerPHD-type 2
HgeneBPTFchr17:65850878chr17:63164317ENST00000306378+2282867_2918478.66666666666672921.0Zinc fingerPHD-type 2
HgeneBPTFchr17:65850878chr17:63164317ENST00000321892+2302867_2918478.66666666666673047.0Zinc fingerPHD-type 2
HgeneBPTFchr17:65850878chr17:63164317ENST00000335221+2302867_2918478.66666666666672904.0Zinc fingerPHD-type 2
HgeneBPTFchr17:65850878chr17:63164318ENST00000306378+2282867_2918478.66666666666672921.0Zinc fingerPHD-type 2
HgeneBPTFchr17:65850878chr17:63164318ENST00000321892+2302867_2918478.66666666666673047.0Zinc fingerPHD-type 2
HgeneBPTFchr17:65850878chr17:63164318ENST00000335221+2302867_2918478.66666666666672904.0Zinc fingerPHD-type 2
TgeneRGS9chr17:65850877chr17:63164317ENST0000026240661930_105166.66666666666666675.0DomainDEP
TgeneRGS9chr17:65850877chr17:63164317ENST0000044999661930_105166.66666666666666672.0DomainDEP
TgeneRGS9chr17:65850878chr17:63164317ENST0000026240661930_105166.66666666666666675.0DomainDEP
TgeneRGS9chr17:65850878chr17:63164317ENST0000044999661930_105166.66666666666666672.0DomainDEP
TgeneRGS9chr17:65850878chr17:63164318ENST0000026240661930_105166.66666666666666675.0DomainDEP
TgeneRGS9chr17:65850878chr17:63164318ENST0000044999661930_105166.66666666666666672.0DomainDEP


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Fusion Protein-Protein Interaction


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type from validated records (BIOGRID-3.4.160)
GenePPI interactors


check button Protein-protein interactors based on sequence similarity (STRING)
GeneSTRING network
BPTF
RGS9


check button - Retained interactions in fusion protein (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost interactions due to fusion (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneBPTFchr17:65850877chr17:63164317ENST00000306378+228640_749478.66666666666672921.0KEAP1
HgeneBPTFchr17:65850877chr17:63164317ENST00000321892+230640_749478.66666666666673047.0KEAP1
HgeneBPTFchr17:65850877chr17:63164317ENST00000335221+230640_749478.66666666666672904.0KEAP1
HgeneBPTFchr17:65850878chr17:63164317ENST00000306378+228640_749478.66666666666672921.0KEAP1
HgeneBPTFchr17:65850878chr17:63164317ENST00000321892+230640_749478.66666666666673047.0KEAP1
HgeneBPTFchr17:65850878chr17:63164317ENST00000335221+230640_749478.66666666666672904.0KEAP1
HgeneBPTFchr17:65850878chr17:63164318ENST00000306378+228640_749478.66666666666672921.0KEAP1
HgeneBPTFchr17:65850878chr17:63164318ENST00000321892+230640_749478.66666666666673047.0KEAP1
HgeneBPTFchr17:65850878chr17:63164318ENST00000335221+230640_749478.66666666666672904.0KEAP1
HgeneBPTFchr17:65850877chr17:63164317ENST00000306378+228839_921478.66666666666672921.0MAZ
HgeneBPTFchr17:65850877chr17:63164317ENST00000321892+230839_921478.66666666666673047.0MAZ
HgeneBPTFchr17:65850877chr17:63164317ENST00000335221+230839_921478.66666666666672904.0MAZ
HgeneBPTFchr17:65850878chr17:63164317ENST00000306378+228839_921478.66666666666672921.0MAZ
HgeneBPTFchr17:65850878chr17:63164317ENST00000321892+230839_921478.66666666666673047.0MAZ
HgeneBPTFchr17:65850878chr17:63164317ENST00000335221+230839_921478.66666666666672904.0MAZ
HgeneBPTFchr17:65850878chr17:63164318ENST00000306378+228839_921478.66666666666672921.0MAZ
HgeneBPTFchr17:65850878chr17:63164318ENST00000321892+230839_921478.66666666666673047.0MAZ
HgeneBPTFchr17:65850878chr17:63164318ENST00000335221+230839_921478.66666666666672904.0MAZ


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Related Drugs to BPTF-RGS9


check button Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDrugSourcePMID

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Related Diseases to BPTF-RGS9


check button Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDiseaseSourcePMID

check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource