UTHEALTH HOME    ABOUT SBMI    A-Z    WEBMAIL    INSIDE THE UNIVERSITY
FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact

Terms of Use
Center for Computational Systems Medicine level1
leaf

Fusion Gene Summary

leaf

Fusion Gene Sample Information

leaf

Fusion ORF Analysis

leaf

Fusion Amino Acid Sequences

leaf

Fusion Protein Functional Features

leaf

Fusion Protein-Protein Interaction

leaf

Related drugs with this fusion protein

leaf

Related disease with this fusion protein

Fusion Protein:ZNF331-WDR37

Fusion Protein Summary

check button Fusion gene summary
Fusion partner gene informationFusion gene name: ZNF331-WDR37
FusionPDB ID: 101886
FusionGDB2.0 ID: 101886
HgeneTgene
Gene symbol

ZNF331

WDR37

Gene ID

55422

22884

Gene namezinc finger protein 331WD repeat domain 37
SynonymsRITA|ZNF361|ZNF463NOCGUS
Cytomap

19q13.42

10p15.3

Type of geneprotein-codingprotein-coding
Descriptionzinc finger protein 331C2H2-like zinc finger protein rearranged in thyroid adenomasKRAB zinc finger proteinzinc finger protein 361zinc finger protein 463WD repeat-containing protein 37
Modification date2020031320200322
UniProtAcc..
Ensembl transtripts involved in fusion geneENST idsENST00000253144, ENST00000411977, 
ENST00000449416, ENST00000511154, 
ENST00000511593, ENST00000512387, 
ENST00000513265, ENST00000513999, 
ENST00000513929, 		ENST00000482165, 
ENST00000263150, ENST00000358220, 
ENST00000381329, 
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)* DoF score7 X 6 X 4=1688 X 6 X 5=240
# samples 78
** MAII scorelog2(7/168*10)=-1.26303440583379
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(8/240*10)=-1.58496250072116
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context (manual curation of fusion genes in FusionPDB)

PubMed: ZNF331 [Title/Abstract] AND WDR37 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)ZNF331(54074984)-WDR37(1125950), # samples:1
Anticipated loss of major functional domain due to fusion event.ZNF331-WDR37 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ZNF331-WDR37 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across ZNF331 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across WDR37 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure


Top

Fusion Gene Sample Information

check buttonFusion gene information from FusionGDB2.0.
check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChiTaRS5.0N/ADB086777ZNF331chr19

54074984

+WDR37chr10

1125950

+


Top

Fusion ORF Analysis


check buttonFusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000253144ZNF331chr1954074984+ENST00000358220WDR37chr101125950+5672146913332718461
ENST00000253144ZNF331chr1954074984+ENST00000381329WDR37chr101125950+2340146913331983216
ENST00000253144ZNF331chr1954074984+ENST00000263150WDR37chr101125950+5545146913332718461
ENST00000511593ZNF331chr1954074984+ENST00000358220WDR37chr101125950+48036004641849461
ENST00000511593ZNF331chr1954074984+ENST00000381329WDR37chr101125950+14716004641114216
ENST00000511593ZNF331chr1954074984+ENST00000263150WDR37chr101125950+46766004641849461
ENST00000449416ZNF331chr1954074984+ENST00000358220WDR37chr101125950+44472441081493461
ENST00000449416ZNF331chr1954074984+ENST00000381329WDR37chr101125950+1115244108758216
ENST00000449416ZNF331chr1954074984+ENST00000263150WDR37chr101125950+43202441081493461
ENST00000411977ZNF331chr1954074984+ENST00000358220WDR37chr101125950+47615584221807461
ENST00000411977ZNF331chr1954074984+ENST00000381329WDR37chr101125950+14295584221072216
ENST00000411977ZNF331chr1954074984+ENST00000263150WDR37chr101125950+46345584221807461
ENST00000511154ZNF331chr1954074984+ENST00000358220WDR37chr101125950+46334302941679461
ENST00000511154ZNF331chr1954074984+ENST00000381329WDR37chr101125950+1301430294944216
ENST00000511154ZNF331chr1954074984+ENST00000263150WDR37chr101125950+45064302941679461
ENST00000513999ZNF331chr1954074984+ENST00000358220WDR37chr101125950+47085053691754461
ENST00000513999ZNF331chr1954074984+ENST00000381329WDR37chr101125950+13765053691019216
ENST00000513999ZNF331chr1954074984+ENST00000263150WDR37chr101125950+45815053691754461
ENST00000512387ZNF331chr1954074984+ENST00000358220WDR37chr101125950+46404373011686461
ENST00000512387ZNF331chr1954074984+ENST00000381329WDR37chr101125950+1308437301951216
ENST00000512387ZNF331chr1954074984+ENST00000263150WDR37chr101125950+45134373011686461
ENST00000513265ZNF331chr1954074984+ENST00000358220WDR37chr101125950+45383351991584461
ENST00000513265ZNF331chr1954074984+ENST00000381329WDR37chr101125950+1206335199849216
ENST00000513265ZNF331chr1954074984+ENST00000263150WDR37chr101125950+44113351991584461

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000253144ENST00000358220ZNF331chr1954074984+WDR37chr101125950+0.0010897830.9989102
ENST00000253144ENST00000381329ZNF331chr1954074984+WDR37chr101125950+0.0053923950.99460757
ENST00000253144ENST00000263150ZNF331chr1954074984+WDR37chr101125950+0.0011449170.9988551
ENST00000511593ENST00000358220ZNF331chr1954074984+WDR37chr101125950+0.001203390.9987966
ENST00000511593ENST00000381329ZNF331chr1954074984+WDR37chr101125950+0.0083254180.9916746
ENST00000511593ENST00000263150ZNF331chr1954074984+WDR37chr101125950+0.0012801190.99871993
ENST00000449416ENST00000358220ZNF331chr1954074984+WDR37chr101125950+0.0010846840.9989153
ENST00000449416ENST00000381329ZNF331chr1954074984+WDR37chr101125950+0.0085797330.99142027
ENST00000449416ENST00000263150ZNF331chr1954074984+WDR37chr101125950+0.0011570920.99884284
ENST00000411977ENST00000358220ZNF331chr1954074984+WDR37chr101125950+0.0013343810.9986656
ENST00000411977ENST00000381329ZNF331chr1954074984+WDR37chr101125950+0.0086704270.99132955
ENST00000411977ENST00000263150ZNF331chr1954074984+WDR37chr101125950+0.0014153090.99858475
ENST00000511154ENST00000358220ZNF331chr1954074984+WDR37chr101125950+0.0012585960.99874145
ENST00000511154ENST00000381329ZNF331chr1954074984+WDR37chr101125950+0.0087735780.9912264
ENST00000511154ENST00000263150ZNF331chr1954074984+WDR37chr101125950+0.0013345410.99866545
ENST00000513999ENST00000358220ZNF331chr1954074984+WDR37chr101125950+0.001332230.99866784
ENST00000513999ENST00000381329ZNF331chr1954074984+WDR37chr101125950+0.0100441050.9899559
ENST00000513999ENST00000263150ZNF331chr1954074984+WDR37chr101125950+0.0014204630.9985795
ENST00000512387ENST00000358220ZNF331chr1954074984+WDR37chr101125950+0.00126580.9987342
ENST00000512387ENST00000381329ZNF331chr1954074984+WDR37chr101125950+0.0074008770.9925991
ENST00000512387ENST00000263150ZNF331chr1954074984+WDR37chr101125950+0.0013402610.99865973
ENST00000513265ENST00000358220ZNF331chr1954074984+WDR37chr101125950+0.0012390780.99876094
ENST00000513265ENST00000381329ZNF331chr1954074984+WDR37chr101125950+0.008761470.99123853
ENST00000513265ENST00000263150ZNF331chr1954074984+WDR37chr101125950+0.0013157730.9986842

Top

Fusion Amino Acid Sequences


check button For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

>101886_101886_1_ZNF331-WDR37_ZNF331_chr19_54074984_ENST00000253144_WDR37_chr10_1125950_ENST00000263150_length(amino acids)=461AA_BP=45
MAQGLVTFADVAIDFSQEEWACLNSAQRDLYWDVMLENYSNLVSLVRREIDTLNERLAAEGQAIDGAELSKGQLKTKASHSTSQLSQKLK
TTYKASTSKIVSSFKTTTSRAACQLVKEYIGHRDGIWDVSVAKTQPVVLGTASADHTALLWSIETGKCLVKYAGHVGSVNSIKFHPSEQL
ALTASGDQTAHIWRYAVQLPTPQPVADTSISGEDEVECSDKDEPDLDGDVSSDCPTIRVPLTSLKSHQGVVIASDWLVGGKQAVTASWDR
TANLYDVETSELVHSLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFRDPSIHSVNVFQGHTDTVTSAVFTVGDNVVSGSDDRTVKVW
DLKNMRSPIATIRTDSAINRINVCVGQKIIALPHDNRQVRLFDMSGVRLARLPRSSRQGHRRMVCCSAWSEDHPVCNLFTCGFDRQAIGW

--------------------------------------------------------------

>101886_101886_2_ZNF331-WDR37_ZNF331_chr19_54074984_ENST00000253144_WDR37_chr10_1125950_ENST00000358220_length(amino acids)=461AA_BP=45
MAQGLVTFADVAIDFSQEEWACLNSAQRDLYWDVMLENYSNLVSLVRREIDTLNERLAAEGQAIDGAELSKGQLKTKASHSTSQLSQKLK
TTYKASTSKIVSSFKTTTSRAACQLVKEYIGHRDGIWDVSVAKTQPVVLGTASADHTALLWSIETGKCLVKYAGHVGSVNSIKFHPSEQL
ALTASGDQTAHIWRYAVQLPTPQPVADTSISGEDEVECSDKDEPDLDGDVSSDCPTIRVPLTSLKSHQGVVIASDWLVGGKQAVTASWDR
TANLYDVETSELVHSLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFRDPSIHSVNVFQGHTDTVTSAVFTVGDNVVSGSDDRTVKVW
DLKNMRSPIATIRTDSAINRINVCVGQKIIALPHDNRQVRLFDMSGVRLARLPRSSRQGHRRMVCCSAWSEDHPVCNLFTCGFDRQAIGW

--------------------------------------------------------------

>101886_101886_3_ZNF331-WDR37_ZNF331_chr19_54074984_ENST00000253144_WDR37_chr10_1125950_ENST00000381329_length(amino acids)=216AA_BP=45
MAQGLVTFADVAIDFSQEEWACLNSAQRDLYWDVMLENYSNLVSLVRREIDTLNERLAAEGQAIDGAELSKGQLKTKASHSTSQLSQKLK
TTYKASTSKIVSSFKTTTSRAACQLVKEYIGHRDGIWDVSVAKTQPVVLGTASADHTALLWSIETGKCLVKYAGHVGSVNSIKFHPSEQL

--------------------------------------------------------------

>101886_101886_4_ZNF331-WDR37_ZNF331_chr19_54074984_ENST00000411977_WDR37_chr10_1125950_ENST00000263150_length(amino acids)=461AA_BP=45
MAQGLVTFADVAIDFSQEEWACLNSAQRDLYWDVMLENYSNLVSLVRREIDTLNERLAAEGQAIDGAELSKGQLKTKASHSTSQLSQKLK
TTYKASTSKIVSSFKTTTSRAACQLVKEYIGHRDGIWDVSVAKTQPVVLGTASADHTALLWSIETGKCLVKYAGHVGSVNSIKFHPSEQL
ALTASGDQTAHIWRYAVQLPTPQPVADTSISGEDEVECSDKDEPDLDGDVSSDCPTIRVPLTSLKSHQGVVIASDWLVGGKQAVTASWDR
TANLYDVETSELVHSLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFRDPSIHSVNVFQGHTDTVTSAVFTVGDNVVSGSDDRTVKVW
DLKNMRSPIATIRTDSAINRINVCVGQKIIALPHDNRQVRLFDMSGVRLARLPRSSRQGHRRMVCCSAWSEDHPVCNLFTCGFDRQAIGW

--------------------------------------------------------------

>101886_101886_5_ZNF331-WDR37_ZNF331_chr19_54074984_ENST00000411977_WDR37_chr10_1125950_ENST00000358220_length(amino acids)=461AA_BP=45
MAQGLVTFADVAIDFSQEEWACLNSAQRDLYWDVMLENYSNLVSLVRREIDTLNERLAAEGQAIDGAELSKGQLKTKASHSTSQLSQKLK
TTYKASTSKIVSSFKTTTSRAACQLVKEYIGHRDGIWDVSVAKTQPVVLGTASADHTALLWSIETGKCLVKYAGHVGSVNSIKFHPSEQL
ALTASGDQTAHIWRYAVQLPTPQPVADTSISGEDEVECSDKDEPDLDGDVSSDCPTIRVPLTSLKSHQGVVIASDWLVGGKQAVTASWDR
TANLYDVETSELVHSLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFRDPSIHSVNVFQGHTDTVTSAVFTVGDNVVSGSDDRTVKVW
DLKNMRSPIATIRTDSAINRINVCVGQKIIALPHDNRQVRLFDMSGVRLARLPRSSRQGHRRMVCCSAWSEDHPVCNLFTCGFDRQAIGW

--------------------------------------------------------------

>101886_101886_6_ZNF331-WDR37_ZNF331_chr19_54074984_ENST00000411977_WDR37_chr10_1125950_ENST00000381329_length(amino acids)=216AA_BP=45
MAQGLVTFADVAIDFSQEEWACLNSAQRDLYWDVMLENYSNLVSLVRREIDTLNERLAAEGQAIDGAELSKGQLKTKASHSTSQLSQKLK
TTYKASTSKIVSSFKTTTSRAACQLVKEYIGHRDGIWDVSVAKTQPVVLGTASADHTALLWSIETGKCLVKYAGHVGSVNSIKFHPSEQL

--------------------------------------------------------------

>101886_101886_7_ZNF331-WDR37_ZNF331_chr19_54074984_ENST00000449416_WDR37_chr10_1125950_ENST00000263150_length(amino acids)=461AA_BP=45
MAQGLVTFADVAIDFSQEEWACLNSAQRDLYWDVMLENYSNLVSLVRREIDTLNERLAAEGQAIDGAELSKGQLKTKASHSTSQLSQKLK
TTYKASTSKIVSSFKTTTSRAACQLVKEYIGHRDGIWDVSVAKTQPVVLGTASADHTALLWSIETGKCLVKYAGHVGSVNSIKFHPSEQL
ALTASGDQTAHIWRYAVQLPTPQPVADTSISGEDEVECSDKDEPDLDGDVSSDCPTIRVPLTSLKSHQGVVIASDWLVGGKQAVTASWDR
TANLYDVETSELVHSLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFRDPSIHSVNVFQGHTDTVTSAVFTVGDNVVSGSDDRTVKVW
DLKNMRSPIATIRTDSAINRINVCVGQKIIALPHDNRQVRLFDMSGVRLARLPRSSRQGHRRMVCCSAWSEDHPVCNLFTCGFDRQAIGW

--------------------------------------------------------------

>101886_101886_8_ZNF331-WDR37_ZNF331_chr19_54074984_ENST00000449416_WDR37_chr10_1125950_ENST00000358220_length(amino acids)=461AA_BP=45
MAQGLVTFADVAIDFSQEEWACLNSAQRDLYWDVMLENYSNLVSLVRREIDTLNERLAAEGQAIDGAELSKGQLKTKASHSTSQLSQKLK
TTYKASTSKIVSSFKTTTSRAACQLVKEYIGHRDGIWDVSVAKTQPVVLGTASADHTALLWSIETGKCLVKYAGHVGSVNSIKFHPSEQL
ALTASGDQTAHIWRYAVQLPTPQPVADTSISGEDEVECSDKDEPDLDGDVSSDCPTIRVPLTSLKSHQGVVIASDWLVGGKQAVTASWDR
TANLYDVETSELVHSLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFRDPSIHSVNVFQGHTDTVTSAVFTVGDNVVSGSDDRTVKVW
DLKNMRSPIATIRTDSAINRINVCVGQKIIALPHDNRQVRLFDMSGVRLARLPRSSRQGHRRMVCCSAWSEDHPVCNLFTCGFDRQAIGW

--------------------------------------------------------------

>101886_101886_9_ZNF331-WDR37_ZNF331_chr19_54074984_ENST00000449416_WDR37_chr10_1125950_ENST00000381329_length(amino acids)=216AA_BP=45
MAQGLVTFADVAIDFSQEEWACLNSAQRDLYWDVMLENYSNLVSLVRREIDTLNERLAAEGQAIDGAELSKGQLKTKASHSTSQLSQKLK
TTYKASTSKIVSSFKTTTSRAACQLVKEYIGHRDGIWDVSVAKTQPVVLGTASADHTALLWSIETGKCLVKYAGHVGSVNSIKFHPSEQL

--------------------------------------------------------------

>101886_101886_10_ZNF331-WDR37_ZNF331_chr19_54074984_ENST00000511154_WDR37_chr10_1125950_ENST00000263150_length(amino acids)=461AA_BP=45
MAQGLVTFADVAIDFSQEEWACLNSAQRDLYWDVMLENYSNLVSLVRREIDTLNERLAAEGQAIDGAELSKGQLKTKASHSTSQLSQKLK
TTYKASTSKIVSSFKTTTSRAACQLVKEYIGHRDGIWDVSVAKTQPVVLGTASADHTALLWSIETGKCLVKYAGHVGSVNSIKFHPSEQL
ALTASGDQTAHIWRYAVQLPTPQPVADTSISGEDEVECSDKDEPDLDGDVSSDCPTIRVPLTSLKSHQGVVIASDWLVGGKQAVTASWDR
TANLYDVETSELVHSLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFRDPSIHSVNVFQGHTDTVTSAVFTVGDNVVSGSDDRTVKVW
DLKNMRSPIATIRTDSAINRINVCVGQKIIALPHDNRQVRLFDMSGVRLARLPRSSRQGHRRMVCCSAWSEDHPVCNLFTCGFDRQAIGW

--------------------------------------------------------------

>101886_101886_11_ZNF331-WDR37_ZNF331_chr19_54074984_ENST00000511154_WDR37_chr10_1125950_ENST00000358220_length(amino acids)=461AA_BP=45
MAQGLVTFADVAIDFSQEEWACLNSAQRDLYWDVMLENYSNLVSLVRREIDTLNERLAAEGQAIDGAELSKGQLKTKASHSTSQLSQKLK
TTYKASTSKIVSSFKTTTSRAACQLVKEYIGHRDGIWDVSVAKTQPVVLGTASADHTALLWSIETGKCLVKYAGHVGSVNSIKFHPSEQL
ALTASGDQTAHIWRYAVQLPTPQPVADTSISGEDEVECSDKDEPDLDGDVSSDCPTIRVPLTSLKSHQGVVIASDWLVGGKQAVTASWDR
TANLYDVETSELVHSLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFRDPSIHSVNVFQGHTDTVTSAVFTVGDNVVSGSDDRTVKVW
DLKNMRSPIATIRTDSAINRINVCVGQKIIALPHDNRQVRLFDMSGVRLARLPRSSRQGHRRMVCCSAWSEDHPVCNLFTCGFDRQAIGW

--------------------------------------------------------------

>101886_101886_12_ZNF331-WDR37_ZNF331_chr19_54074984_ENST00000511154_WDR37_chr10_1125950_ENST00000381329_length(amino acids)=216AA_BP=45
MAQGLVTFADVAIDFSQEEWACLNSAQRDLYWDVMLENYSNLVSLVRREIDTLNERLAAEGQAIDGAELSKGQLKTKASHSTSQLSQKLK
TTYKASTSKIVSSFKTTTSRAACQLVKEYIGHRDGIWDVSVAKTQPVVLGTASADHTALLWSIETGKCLVKYAGHVGSVNSIKFHPSEQL

--------------------------------------------------------------

>101886_101886_13_ZNF331-WDR37_ZNF331_chr19_54074984_ENST00000511593_WDR37_chr10_1125950_ENST00000263150_length(amino acids)=461AA_BP=45
MAQGLVTFADVAIDFSQEEWACLNSAQRDLYWDVMLENYSNLVSLVRREIDTLNERLAAEGQAIDGAELSKGQLKTKASHSTSQLSQKLK
TTYKASTSKIVSSFKTTTSRAACQLVKEYIGHRDGIWDVSVAKTQPVVLGTASADHTALLWSIETGKCLVKYAGHVGSVNSIKFHPSEQL
ALTASGDQTAHIWRYAVQLPTPQPVADTSISGEDEVECSDKDEPDLDGDVSSDCPTIRVPLTSLKSHQGVVIASDWLVGGKQAVTASWDR
TANLYDVETSELVHSLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFRDPSIHSVNVFQGHTDTVTSAVFTVGDNVVSGSDDRTVKVW
DLKNMRSPIATIRTDSAINRINVCVGQKIIALPHDNRQVRLFDMSGVRLARLPRSSRQGHRRMVCCSAWSEDHPVCNLFTCGFDRQAIGW

--------------------------------------------------------------

>101886_101886_14_ZNF331-WDR37_ZNF331_chr19_54074984_ENST00000511593_WDR37_chr10_1125950_ENST00000358220_length(amino acids)=461AA_BP=45
MAQGLVTFADVAIDFSQEEWACLNSAQRDLYWDVMLENYSNLVSLVRREIDTLNERLAAEGQAIDGAELSKGQLKTKASHSTSQLSQKLK
TTYKASTSKIVSSFKTTTSRAACQLVKEYIGHRDGIWDVSVAKTQPVVLGTASADHTALLWSIETGKCLVKYAGHVGSVNSIKFHPSEQL
ALTASGDQTAHIWRYAVQLPTPQPVADTSISGEDEVECSDKDEPDLDGDVSSDCPTIRVPLTSLKSHQGVVIASDWLVGGKQAVTASWDR
TANLYDVETSELVHSLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFRDPSIHSVNVFQGHTDTVTSAVFTVGDNVVSGSDDRTVKVW
DLKNMRSPIATIRTDSAINRINVCVGQKIIALPHDNRQVRLFDMSGVRLARLPRSSRQGHRRMVCCSAWSEDHPVCNLFTCGFDRQAIGW

--------------------------------------------------------------

>101886_101886_15_ZNF331-WDR37_ZNF331_chr19_54074984_ENST00000511593_WDR37_chr10_1125950_ENST00000381329_length(amino acids)=216AA_BP=45
MAQGLVTFADVAIDFSQEEWACLNSAQRDLYWDVMLENYSNLVSLVRREIDTLNERLAAEGQAIDGAELSKGQLKTKASHSTSQLSQKLK
TTYKASTSKIVSSFKTTTSRAACQLVKEYIGHRDGIWDVSVAKTQPVVLGTASADHTALLWSIETGKCLVKYAGHVGSVNSIKFHPSEQL

--------------------------------------------------------------

>101886_101886_16_ZNF331-WDR37_ZNF331_chr19_54074984_ENST00000512387_WDR37_chr10_1125950_ENST00000263150_length(amino acids)=461AA_BP=45
MAQGLVTFADVAIDFSQEEWACLNSAQRDLYWDVMLENYSNLVSLVRREIDTLNERLAAEGQAIDGAELSKGQLKTKASHSTSQLSQKLK
TTYKASTSKIVSSFKTTTSRAACQLVKEYIGHRDGIWDVSVAKTQPVVLGTASADHTALLWSIETGKCLVKYAGHVGSVNSIKFHPSEQL
ALTASGDQTAHIWRYAVQLPTPQPVADTSISGEDEVECSDKDEPDLDGDVSSDCPTIRVPLTSLKSHQGVVIASDWLVGGKQAVTASWDR
TANLYDVETSELVHSLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFRDPSIHSVNVFQGHTDTVTSAVFTVGDNVVSGSDDRTVKVW
DLKNMRSPIATIRTDSAINRINVCVGQKIIALPHDNRQVRLFDMSGVRLARLPRSSRQGHRRMVCCSAWSEDHPVCNLFTCGFDRQAIGW

--------------------------------------------------------------

>101886_101886_17_ZNF331-WDR37_ZNF331_chr19_54074984_ENST00000512387_WDR37_chr10_1125950_ENST00000358220_length(amino acids)=461AA_BP=45
MAQGLVTFADVAIDFSQEEWACLNSAQRDLYWDVMLENYSNLVSLVRREIDTLNERLAAEGQAIDGAELSKGQLKTKASHSTSQLSQKLK
TTYKASTSKIVSSFKTTTSRAACQLVKEYIGHRDGIWDVSVAKTQPVVLGTASADHTALLWSIETGKCLVKYAGHVGSVNSIKFHPSEQL
ALTASGDQTAHIWRYAVQLPTPQPVADTSISGEDEVECSDKDEPDLDGDVSSDCPTIRVPLTSLKSHQGVVIASDWLVGGKQAVTASWDR
TANLYDVETSELVHSLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFRDPSIHSVNVFQGHTDTVTSAVFTVGDNVVSGSDDRTVKVW
DLKNMRSPIATIRTDSAINRINVCVGQKIIALPHDNRQVRLFDMSGVRLARLPRSSRQGHRRMVCCSAWSEDHPVCNLFTCGFDRQAIGW

--------------------------------------------------------------

>101886_101886_18_ZNF331-WDR37_ZNF331_chr19_54074984_ENST00000512387_WDR37_chr10_1125950_ENST00000381329_length(amino acids)=216AA_BP=45
MAQGLVTFADVAIDFSQEEWACLNSAQRDLYWDVMLENYSNLVSLVRREIDTLNERLAAEGQAIDGAELSKGQLKTKASHSTSQLSQKLK
TTYKASTSKIVSSFKTTTSRAACQLVKEYIGHRDGIWDVSVAKTQPVVLGTASADHTALLWSIETGKCLVKYAGHVGSVNSIKFHPSEQL

--------------------------------------------------------------

>101886_101886_19_ZNF331-WDR37_ZNF331_chr19_54074984_ENST00000513265_WDR37_chr10_1125950_ENST00000263150_length(amino acids)=461AA_BP=45
MAQGLVTFADVAIDFSQEEWACLNSAQRDLYWDVMLENYSNLVSLVRREIDTLNERLAAEGQAIDGAELSKGQLKTKASHSTSQLSQKLK
TTYKASTSKIVSSFKTTTSRAACQLVKEYIGHRDGIWDVSVAKTQPVVLGTASADHTALLWSIETGKCLVKYAGHVGSVNSIKFHPSEQL
ALTASGDQTAHIWRYAVQLPTPQPVADTSISGEDEVECSDKDEPDLDGDVSSDCPTIRVPLTSLKSHQGVVIASDWLVGGKQAVTASWDR
TANLYDVETSELVHSLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFRDPSIHSVNVFQGHTDTVTSAVFTVGDNVVSGSDDRTVKVW
DLKNMRSPIATIRTDSAINRINVCVGQKIIALPHDNRQVRLFDMSGVRLARLPRSSRQGHRRMVCCSAWSEDHPVCNLFTCGFDRQAIGW

--------------------------------------------------------------

>101886_101886_20_ZNF331-WDR37_ZNF331_chr19_54074984_ENST00000513265_WDR37_chr10_1125950_ENST00000358220_length(amino acids)=461AA_BP=45
MAQGLVTFADVAIDFSQEEWACLNSAQRDLYWDVMLENYSNLVSLVRREIDTLNERLAAEGQAIDGAELSKGQLKTKASHSTSQLSQKLK
TTYKASTSKIVSSFKTTTSRAACQLVKEYIGHRDGIWDVSVAKTQPVVLGTASADHTALLWSIETGKCLVKYAGHVGSVNSIKFHPSEQL
ALTASGDQTAHIWRYAVQLPTPQPVADTSISGEDEVECSDKDEPDLDGDVSSDCPTIRVPLTSLKSHQGVVIASDWLVGGKQAVTASWDR
TANLYDVETSELVHSLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFRDPSIHSVNVFQGHTDTVTSAVFTVGDNVVSGSDDRTVKVW
DLKNMRSPIATIRTDSAINRINVCVGQKIIALPHDNRQVRLFDMSGVRLARLPRSSRQGHRRMVCCSAWSEDHPVCNLFTCGFDRQAIGW

--------------------------------------------------------------

>101886_101886_21_ZNF331-WDR37_ZNF331_chr19_54074984_ENST00000513265_WDR37_chr10_1125950_ENST00000381329_length(amino acids)=216AA_BP=45
MAQGLVTFADVAIDFSQEEWACLNSAQRDLYWDVMLENYSNLVSLVRREIDTLNERLAAEGQAIDGAELSKGQLKTKASHSTSQLSQKLK
TTYKASTSKIVSSFKTTTSRAACQLVKEYIGHRDGIWDVSVAKTQPVVLGTASADHTALLWSIETGKCLVKYAGHVGSVNSIKFHPSEQL

--------------------------------------------------------------

>101886_101886_22_ZNF331-WDR37_ZNF331_chr19_54074984_ENST00000513999_WDR37_chr10_1125950_ENST00000263150_length(amino acids)=461AA_BP=45
MAQGLVTFADVAIDFSQEEWACLNSAQRDLYWDVMLENYSNLVSLVRREIDTLNERLAAEGQAIDGAELSKGQLKTKASHSTSQLSQKLK
TTYKASTSKIVSSFKTTTSRAACQLVKEYIGHRDGIWDVSVAKTQPVVLGTASADHTALLWSIETGKCLVKYAGHVGSVNSIKFHPSEQL
ALTASGDQTAHIWRYAVQLPTPQPVADTSISGEDEVECSDKDEPDLDGDVSSDCPTIRVPLTSLKSHQGVVIASDWLVGGKQAVTASWDR
TANLYDVETSELVHSLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFRDPSIHSVNVFQGHTDTVTSAVFTVGDNVVSGSDDRTVKVW
DLKNMRSPIATIRTDSAINRINVCVGQKIIALPHDNRQVRLFDMSGVRLARLPRSSRQGHRRMVCCSAWSEDHPVCNLFTCGFDRQAIGW

--------------------------------------------------------------

>101886_101886_23_ZNF331-WDR37_ZNF331_chr19_54074984_ENST00000513999_WDR37_chr10_1125950_ENST00000358220_length(amino acids)=461AA_BP=45
MAQGLVTFADVAIDFSQEEWACLNSAQRDLYWDVMLENYSNLVSLVRREIDTLNERLAAEGQAIDGAELSKGQLKTKASHSTSQLSQKLK
TTYKASTSKIVSSFKTTTSRAACQLVKEYIGHRDGIWDVSVAKTQPVVLGTASADHTALLWSIETGKCLVKYAGHVGSVNSIKFHPSEQL
ALTASGDQTAHIWRYAVQLPTPQPVADTSISGEDEVECSDKDEPDLDGDVSSDCPTIRVPLTSLKSHQGVVIASDWLVGGKQAVTASWDR
TANLYDVETSELVHSLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFRDPSIHSVNVFQGHTDTVTSAVFTVGDNVVSGSDDRTVKVW
DLKNMRSPIATIRTDSAINRINVCVGQKIIALPHDNRQVRLFDMSGVRLARLPRSSRQGHRRMVCCSAWSEDHPVCNLFTCGFDRQAIGW

--------------------------------------------------------------

>101886_101886_24_ZNF331-WDR37_ZNF331_chr19_54074984_ENST00000513999_WDR37_chr10_1125950_ENST00000381329_length(amino acids)=216AA_BP=45
MAQGLVTFADVAIDFSQEEWACLNSAQRDLYWDVMLENYSNLVSLVRREIDTLNERLAAEGQAIDGAELSKGQLKTKASHSTSQLSQKLK
TTYKASTSKIVSSFKTTTSRAACQLVKEYIGHRDGIWDVSVAKTQPVVLGTASADHTALLWSIETGKCLVKYAGHVGSVNSIKFHPSEQL

--------------------------------------------------------------

Top

Fusion Protein Functional Features


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr19:54074984/chr10:1125950)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

* Minus value of BPloci means that the break pointn is located before the CDS.
- Retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneWDR37chr19:54074984chr10:1125950ENST00000263150214154_19478.33333333333333495.0RepeatNote=WD 1
TgeneWDR37chr19:54074984chr10:1125950ENST00000263150214197_23678.33333333333333495.0RepeatNote=WD 2
TgeneWDR37chr19:54074984chr10:1125950ENST00000263150214279_31878.33333333333333495.0RepeatNote=WD 3
TgeneWDR37chr19:54074984chr10:1125950ENST00000263150214321_36078.33333333333333495.0RepeatNote=WD 4
TgeneWDR37chr19:54074984chr10:1125950ENST00000263150214365_40378.33333333333333495.0RepeatNote=WD 5
TgeneWDR37chr19:54074984chr10:1125950ENST00000263150214406_44578.33333333333333495.0RepeatNote=WD 6
TgeneWDR37chr19:54074984chr10:1125950ENST00000263150214452_49378.33333333333333495.0RepeatNote=WD 7
TgeneWDR37chr19:54074984chr10:1125950ENST00000358220214154_19478.33333333333333495.0RepeatNote=WD 1
TgeneWDR37chr19:54074984chr10:1125950ENST00000358220214197_23678.33333333333333495.0RepeatNote=WD 2
TgeneWDR37chr19:54074984chr10:1125950ENST00000358220214279_31878.33333333333333495.0RepeatNote=WD 3
TgeneWDR37chr19:54074984chr10:1125950ENST00000358220214321_36078.33333333333333495.0RepeatNote=WD 4
TgeneWDR37chr19:54074984chr10:1125950ENST00000358220214365_40378.33333333333333495.0RepeatNote=WD 5
TgeneWDR37chr19:54074984chr10:1125950ENST00000358220214406_44578.33333333333333495.0RepeatNote=WD 6
TgeneWDR37chr19:54074984chr10:1125950ENST00000358220214452_49378.33333333333333495.0RepeatNote=WD 7

- Not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneZNF331chr19:54074984chr10:1125950ENST00000253144+676_7845.333333333333336464.0DomainKRAB
HgeneZNF331chr19:54074984chr10:1125950ENST00000411977+566_7845.333333333333336464.0DomainKRAB
HgeneZNF331chr19:54074984chr10:1125950ENST00000449416+346_7845.333333333333336464.0DomainKRAB
HgeneZNF331chr19:54074984chr10:1125950ENST00000511154+456_7845.333333333333336464.0DomainKRAB
HgeneZNF331chr19:54074984chr10:1125950ENST00000511593+676_7845.333333333333336464.0DomainKRAB
HgeneZNF331chr19:54074984chr10:1125950ENST00000512387+456_7845.333333333333336464.0DomainKRAB
HgeneZNF331chr19:54074984chr10:1125950ENST00000513999+566_7845.333333333333336464.0DomainKRAB
HgeneZNF331chr19:54074984chr10:1125950ENST00000253144+67131_15345.333333333333336464.0Zinc fingerC2H2-type 1
HgeneZNF331chr19:54074984chr10:1125950ENST00000253144+67159_18145.333333333333336464.0Zinc fingerC2H2-type 2
HgeneZNF331chr19:54074984chr10:1125950ENST00000253144+67187_20945.333333333333336464.0Zinc fingerC2H2-type 3
HgeneZNF331chr19:54074984chr10:1125950ENST00000253144+67215_23745.333333333333336464.0Zinc fingerC2H2-type 4
HgeneZNF331chr19:54074984chr10:1125950ENST00000253144+67243_26545.333333333333336464.0Zinc fingerC2H2-type 5
HgeneZNF331chr19:54074984chr10:1125950ENST00000253144+67271_29345.333333333333336464.0Zinc fingerC2H2-type 6
HgeneZNF331chr19:54074984chr10:1125950ENST00000253144+67299_32145.333333333333336464.0Zinc fingerC2H2-type 7
HgeneZNF331chr19:54074984chr10:1125950ENST00000253144+67327_34945.333333333333336464.0Zinc fingerC2H2-type 8
HgeneZNF331chr19:54074984chr10:1125950ENST00000253144+67355_37745.333333333333336464.0Zinc fingerC2H2-type 9
HgeneZNF331chr19:54074984chr10:1125950ENST00000253144+67383_40545.333333333333336464.0Zinc fingerC2H2-type 10
HgeneZNF331chr19:54074984chr10:1125950ENST00000253144+67411_43345.333333333333336464.0Zinc fingerC2H2-type 11
HgeneZNF331chr19:54074984chr10:1125950ENST00000253144+67439_46145.333333333333336464.0Zinc fingerC2H2-type 12
HgeneZNF331chr19:54074984chr10:1125950ENST00000411977+56131_15345.333333333333336464.0Zinc fingerC2H2-type 1
HgeneZNF331chr19:54074984chr10:1125950ENST00000411977+56159_18145.333333333333336464.0Zinc fingerC2H2-type 2
HgeneZNF331chr19:54074984chr10:1125950ENST00000411977+56187_20945.333333333333336464.0Zinc fingerC2H2-type 3
HgeneZNF331chr19:54074984chr10:1125950ENST00000411977+56215_23745.333333333333336464.0Zinc fingerC2H2-type 4
HgeneZNF331chr19:54074984chr10:1125950ENST00000411977+56243_26545.333333333333336464.0Zinc fingerC2H2-type 5
HgeneZNF331chr19:54074984chr10:1125950ENST00000411977+56271_29345.333333333333336464.0Zinc fingerC2H2-type 6
HgeneZNF331chr19:54074984chr10:1125950ENST00000411977+56299_32145.333333333333336464.0Zinc fingerC2H2-type 7
HgeneZNF331chr19:54074984chr10:1125950ENST00000411977+56327_34945.333333333333336464.0Zinc fingerC2H2-type 8
HgeneZNF331chr19:54074984chr10:1125950ENST00000411977+56355_37745.333333333333336464.0Zinc fingerC2H2-type 9
HgeneZNF331chr19:54074984chr10:1125950ENST00000411977+56383_40545.333333333333336464.0Zinc fingerC2H2-type 10
HgeneZNF331chr19:54074984chr10:1125950ENST00000411977+56411_43345.333333333333336464.0Zinc fingerC2H2-type 11
HgeneZNF331chr19:54074984chr10:1125950ENST00000411977+56439_46145.333333333333336464.0Zinc fingerC2H2-type 12
HgeneZNF331chr19:54074984chr10:1125950ENST00000449416+34131_15345.333333333333336464.0Zinc fingerC2H2-type 1
HgeneZNF331chr19:54074984chr10:1125950ENST00000449416+34159_18145.333333333333336464.0Zinc fingerC2H2-type 2
HgeneZNF331chr19:54074984chr10:1125950ENST00000449416+34187_20945.333333333333336464.0Zinc fingerC2H2-type 3
HgeneZNF331chr19:54074984chr10:1125950ENST00000449416+34215_23745.333333333333336464.0Zinc fingerC2H2-type 4
HgeneZNF331chr19:54074984chr10:1125950ENST00000449416+34243_26545.333333333333336464.0Zinc fingerC2H2-type 5
HgeneZNF331chr19:54074984chr10:1125950ENST00000449416+34271_29345.333333333333336464.0Zinc fingerC2H2-type 6
HgeneZNF331chr19:54074984chr10:1125950ENST00000449416+34299_32145.333333333333336464.0Zinc fingerC2H2-type 7
HgeneZNF331chr19:54074984chr10:1125950ENST00000449416+34327_34945.333333333333336464.0Zinc fingerC2H2-type 8
HgeneZNF331chr19:54074984chr10:1125950ENST00000449416+34355_37745.333333333333336464.0Zinc fingerC2H2-type 9
HgeneZNF331chr19:54074984chr10:1125950ENST00000449416+34383_40545.333333333333336464.0Zinc fingerC2H2-type 10
HgeneZNF331chr19:54074984chr10:1125950ENST00000449416+34411_43345.333333333333336464.0Zinc fingerC2H2-type 11
HgeneZNF331chr19:54074984chr10:1125950ENST00000449416+34439_46145.333333333333336464.0Zinc fingerC2H2-type 12
HgeneZNF331chr19:54074984chr10:1125950ENST00000511154+45131_15345.333333333333336464.0Zinc fingerC2H2-type 1
HgeneZNF331chr19:54074984chr10:1125950ENST00000511154+45159_18145.333333333333336464.0Zinc fingerC2H2-type 2
HgeneZNF331chr19:54074984chr10:1125950ENST00000511154+45187_20945.333333333333336464.0Zinc fingerC2H2-type 3
HgeneZNF331chr19:54074984chr10:1125950ENST00000511154+45215_23745.333333333333336464.0Zinc fingerC2H2-type 4
HgeneZNF331chr19:54074984chr10:1125950ENST00000511154+45243_26545.333333333333336464.0Zinc fingerC2H2-type 5
HgeneZNF331chr19:54074984chr10:1125950ENST00000511154+45271_29345.333333333333336464.0Zinc fingerC2H2-type 6
HgeneZNF331chr19:54074984chr10:1125950ENST00000511154+45299_32145.333333333333336464.0Zinc fingerC2H2-type 7
HgeneZNF331chr19:54074984chr10:1125950ENST00000511154+45327_34945.333333333333336464.0Zinc fingerC2H2-type 8
HgeneZNF331chr19:54074984chr10:1125950ENST00000511154+45355_37745.333333333333336464.0Zinc fingerC2H2-type 9
HgeneZNF331chr19:54074984chr10:1125950ENST00000511154+45383_40545.333333333333336464.0Zinc fingerC2H2-type 10
HgeneZNF331chr19:54074984chr10:1125950ENST00000511154+45411_43345.333333333333336464.0Zinc fingerC2H2-type 11
HgeneZNF331chr19:54074984chr10:1125950ENST00000511154+45439_46145.333333333333336464.0Zinc fingerC2H2-type 12
HgeneZNF331chr19:54074984chr10:1125950ENST00000511593+67131_15345.333333333333336464.0Zinc fingerC2H2-type 1
HgeneZNF331chr19:54074984chr10:1125950ENST00000511593+67159_18145.333333333333336464.0Zinc fingerC2H2-type 2
HgeneZNF331chr19:54074984chr10:1125950ENST00000511593+67187_20945.333333333333336464.0Zinc fingerC2H2-type 3
HgeneZNF331chr19:54074984chr10:1125950ENST00000511593+67215_23745.333333333333336464.0Zinc fingerC2H2-type 4
HgeneZNF331chr19:54074984chr10:1125950ENST00000511593+67243_26545.333333333333336464.0Zinc fingerC2H2-type 5
HgeneZNF331chr19:54074984chr10:1125950ENST00000511593+67271_29345.333333333333336464.0Zinc fingerC2H2-type 6
HgeneZNF331chr19:54074984chr10:1125950ENST00000511593+67299_32145.333333333333336464.0Zinc fingerC2H2-type 7
HgeneZNF331chr19:54074984chr10:1125950ENST00000511593+67327_34945.333333333333336464.0Zinc fingerC2H2-type 8
HgeneZNF331chr19:54074984chr10:1125950ENST00000511593+67355_37745.333333333333336464.0Zinc fingerC2H2-type 9
HgeneZNF331chr19:54074984chr10:1125950ENST00000511593+67383_40545.333333333333336464.0Zinc fingerC2H2-type 10
HgeneZNF331chr19:54074984chr10:1125950ENST00000511593+67411_43345.333333333333336464.0Zinc fingerC2H2-type 11
HgeneZNF331chr19:54074984chr10:1125950ENST00000511593+67439_46145.333333333333336464.0Zinc fingerC2H2-type 12
HgeneZNF331chr19:54074984chr10:1125950ENST00000512387+45131_15345.333333333333336464.0Zinc fingerC2H2-type 1
HgeneZNF331chr19:54074984chr10:1125950ENST00000512387+45159_18145.333333333333336464.0Zinc fingerC2H2-type 2
HgeneZNF331chr19:54074984chr10:1125950ENST00000512387+45187_20945.333333333333336464.0Zinc fingerC2H2-type 3
HgeneZNF331chr19:54074984chr10:1125950ENST00000512387+45215_23745.333333333333336464.0Zinc fingerC2H2-type 4
HgeneZNF331chr19:54074984chr10:1125950ENST00000512387+45243_26545.333333333333336464.0Zinc fingerC2H2-type 5
HgeneZNF331chr19:54074984chr10:1125950ENST00000512387+45271_29345.333333333333336464.0Zinc fingerC2H2-type 6
HgeneZNF331chr19:54074984chr10:1125950ENST00000512387+45299_32145.333333333333336464.0Zinc fingerC2H2-type 7
HgeneZNF331chr19:54074984chr10:1125950ENST00000512387+45327_34945.333333333333336464.0Zinc fingerC2H2-type 8
HgeneZNF331chr19:54074984chr10:1125950ENST00000512387+45355_37745.333333333333336464.0Zinc fingerC2H2-type 9
HgeneZNF331chr19:54074984chr10:1125950ENST00000512387+45383_40545.333333333333336464.0Zinc fingerC2H2-type 10
HgeneZNF331chr19:54074984chr10:1125950ENST00000512387+45411_43345.333333333333336464.0Zinc fingerC2H2-type 11
HgeneZNF331chr19:54074984chr10:1125950ENST00000512387+45439_46145.333333333333336464.0Zinc fingerC2H2-type 12
HgeneZNF331chr19:54074984chr10:1125950ENST00000513999+56131_15345.333333333333336464.0Zinc fingerC2H2-type 1
HgeneZNF331chr19:54074984chr10:1125950ENST00000513999+56159_18145.333333333333336464.0Zinc fingerC2H2-type 2
HgeneZNF331chr19:54074984chr10:1125950ENST00000513999+56187_20945.333333333333336464.0Zinc fingerC2H2-type 3
HgeneZNF331chr19:54074984chr10:1125950ENST00000513999+56215_23745.333333333333336464.0Zinc fingerC2H2-type 4
HgeneZNF331chr19:54074984chr10:1125950ENST00000513999+56243_26545.333333333333336464.0Zinc fingerC2H2-type 5
HgeneZNF331chr19:54074984chr10:1125950ENST00000513999+56271_29345.333333333333336464.0Zinc fingerC2H2-type 6
HgeneZNF331chr19:54074984chr10:1125950ENST00000513999+56299_32145.333333333333336464.0Zinc fingerC2H2-type 7
HgeneZNF331chr19:54074984chr10:1125950ENST00000513999+56327_34945.333333333333336464.0Zinc fingerC2H2-type 8
HgeneZNF331chr19:54074984chr10:1125950ENST00000513999+56355_37745.333333333333336464.0Zinc fingerC2H2-type 9
HgeneZNF331chr19:54074984chr10:1125950ENST00000513999+56383_40545.333333333333336464.0Zinc fingerC2H2-type 10
HgeneZNF331chr19:54074984chr10:1125950ENST00000513999+56411_43345.333333333333336464.0Zinc fingerC2H2-type 11
HgeneZNF331chr19:54074984chr10:1125950ENST00000513999+56439_46145.333333333333336464.0Zinc fingerC2H2-type 12


Top

Fusion Protein-Protein Interaction


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type from validated records (BIOGRID-3.4.160)
GenePPI interactors


check button Protein-protein interactors based on sequence similarity (STRING)
GeneSTRING network
ZNF331
WDR37


check button - Retained interactions in fusion protein (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost interactions due to fusion (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs to ZNF331-WDR37


check button Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDrugSourcePMID

Top

Related Diseases to ZNF331-WDR37


check button Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDiseaseSourcePMID

check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource