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Center for Computational Systems Medicine level1
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Fusion Gene Summary

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Fusion Gene Sample Information

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Fusion ORF Analysis

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Fusion Amino Acid Sequences

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Fusion Protein Functional Features

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Fusion Protein-Protein Interaction

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Related drugs with this fusion protein

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Related disease with this fusion protein

Fusion Protein:ZNRF3-EMID1

Fusion Protein Summary

check button Fusion gene summary
Fusion partner gene informationFusion gene name: ZNRF3-EMID1
FusionPDB ID: 103165
FusionGDB2.0 ID: 103165
HgeneTgene
Gene symbol

ZNRF3

EMID1

Gene ID

84133

129080

Gene namezinc and ring finger 3EMI domain containing 1
SynonymsBK747E2.3|RNF203EMI5|EMU1
Cytomap

22q12.1

22q12.2

Type of geneprotein-codingprotein-coding
DescriptionE3 ubiquitin-protein ligase ZNRF3CTA-292E10.6RING finger protein 203RING-type E3 ubiquitin transferase ZNRF3novel C3HC4 type Zinc finger (ring finger)zinc/RING finger protein 3EMI domain-containing protein 1emilin and multimerin domain-containing protein 1
Modification date2020031320200313
UniProtAcc.

Q96A84

Ensembl transtripts involved in fusion geneENST idsENST00000332811, ENST00000402174, 
ENST00000406323, ENST00000544604, 
ENST00000404755, ENST00000404820, 
ENST00000484039, ENST00000334018, 
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)* DoF score26 X 11 X 18=51489 X 12 X 7=756
# samples 3912
** MAII scorelog2(39/5148*10)=-3.72246602447109
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(12/756*10)=-2.65535182861255
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context (manual curation of fusion genes in FusionPDB)

PubMed: ZNRF3 [Title/Abstract] AND EMID1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)ZNRF3(29280054)-EMID1(29610914), # samples:1
ZNRF3(29280054)-EMID1(29610915), # samples:1
ZNRF3(29383189)-EMID1(29650192), # samples:1
ZNRF3(29383189)-EMID1(29639434), # samples:1
Anticipated loss of major functional domain due to fusion event.ZNRF3-EMID1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ZNRF3-EMID1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
ZNRF3-EMID1 seems lost the major protein functional domain in Hgene partner, which is a CGC due to the frame-shifted ORF.
ZNRF3-EMID1 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneZNRF3

GO:0016567

protein ubiquitination

22575959


check buttonFusion gene breakpoints across ZNRF3 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across EMID1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure


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Fusion Gene Sample Information

check buttonFusion gene information from FusionGDB2.0.
check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4ACCTCGA-OR-A5LH-01AZNRF3chr22

29383189

+EMID1chr22

29639434

+
ChimerDB4ACCTCGA-OR-A5LH-01AZNRF3chr22

29383189

+EMID1chr22

29650192

+
ChimerDB4ACCTCGA-OR-A5LO-01AZNRF3chr22

29280054

+EMID1chr22

29610915

+
ChimerDB4ACCTCGA-OR-A5LOZNRF3chr22

29280054

+EMID1chr22

29610914

+


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Fusion ORF Analysis


check buttonFusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000544604ZNRF3chr2229383189+ENST00000334018EMID1chr2229650192+1467601175813212
ENST00000332811ZNRF3chr2229383189+ENST00000334018EMID1chr2229650192+115729157503148
ENST00000402174ZNRF3chr2229383189+ENST00000334018EMID1chr2229650192+108521993431112
ENST00000406323ZNRF3chr2229383189+ENST00000334018EMID1chr2229650192+101615024362112
ENST00000544604ZNRF3chr2229383189+ENST00000334018EMID1chr2229639434+1512601175858227
ENST00000544604ZNRF3chr2229383189+ENST00000404820EMID1chr2229639434+1518601175864229
ENST00000544604ZNRF3chr2229383189+ENST00000404755EMID1chr2229639434+1512601175858227
ENST00000332811ZNRF3chr2229383189+ENST00000334018EMID1chr2229639434+120229157548163
ENST00000332811ZNRF3chr2229383189+ENST00000404820EMID1chr2229639434+120829157554165
ENST00000332811ZNRF3chr2229383189+ENST00000404755EMID1chr2229639434+120229157548163
ENST00000402174ZNRF3chr2229383189+ENST00000334018EMID1chr2229639434+113021993476127
ENST00000402174ZNRF3chr2229383189+ENST00000404820EMID1chr2229639434+113621993482129
ENST00000402174ZNRF3chr2229383189+ENST00000404755EMID1chr2229639434+113021993476127
ENST00000406323ZNRF3chr2229383189+ENST00000334018EMID1chr2229639434+106115024407127
ENST00000406323ZNRF3chr2229383189+ENST00000404820EMID1chr2229639434+106715024413129
ENST00000406323ZNRF3chr2229383189+ENST00000404755EMID1chr2229639434+106115024407127

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000544604ENST00000334018ZNRF3chr2229383189+EMID1chr2229650192+0.139817090.86018294
ENST00000332811ENST00000334018ZNRF3chr2229383189+EMID1chr2229650192+0.0388903580.96110964
ENST00000402174ENST00000334018ZNRF3chr2229383189+EMID1chr2229650192+0.054108490.94589156
ENST00000406323ENST00000334018ZNRF3chr2229383189+EMID1chr2229650192+0.034584490.9654155
ENST00000544604ENST00000334018ZNRF3chr2229383189+EMID1chr2229639434+0.25497480.74502516
ENST00000544604ENST00000404820ZNRF3chr2229383189+EMID1chr2229639434+0.251718130.7482819
ENST00000544604ENST00000404755ZNRF3chr2229383189+EMID1chr2229639434+0.25497480.74502516
ENST00000332811ENST00000334018ZNRF3chr2229383189+EMID1chr2229639434+0.033372490.9666275
ENST00000332811ENST00000404820ZNRF3chr2229383189+EMID1chr2229639434+0.077222840.9227771
ENST00000332811ENST00000404755ZNRF3chr2229383189+EMID1chr2229639434+0.033372490.9666275
ENST00000402174ENST00000334018ZNRF3chr2229383189+EMID1chr2229639434+0.033286510.9667135
ENST00000402174ENST00000404820ZNRF3chr2229383189+EMID1chr2229639434+0.088073550.91192645
ENST00000402174ENST00000404755ZNRF3chr2229383189+EMID1chr2229639434+0.033286510.9667135
ENST00000406323ENST00000334018ZNRF3chr2229383189+EMID1chr2229639434+0.037365840.9626342
ENST00000406323ENST00000404820ZNRF3chr2229383189+EMID1chr2229639434+0.097706480.9022935
ENST00000406323ENST00000404755ZNRF3chr2229383189+EMID1chr2229639434+0.037365840.9626342

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Fusion Amino Acid Sequences


check button For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

>103165_103165_1_ZNRF3-EMID1_ZNRF3_chr22_29383189_ENST00000332811_EMID1_chr22_29639434_ENST00000334018_length(amino acids)=163AA_BP=1
MFESSPSGDYTTYTTGLTGRFSRAGATLSAEGEIVQMHPLGLCNNNDEEDLYEYGWVGVVKLEQPELDPKPCLTVLGKGEPGPKGDPGEK

--------------------------------------------------------------

>103165_103165_2_ZNRF3-EMID1_ZNRF3_chr22_29383189_ENST00000332811_EMID1_chr22_29639434_ENST00000404755_length(amino acids)=163AA_BP=1
MFESSPSGDYTTYTTGLTGRFSRAGATLSAEGEIVQMHPLGLCNNNDEEDLYEYGWVGVVKLEQPELDPKPCLTVLGKGEPGPKGDPGEK

--------------------------------------------------------------

>103165_103165_3_ZNRF3-EMID1_ZNRF3_chr22_29383189_ENST00000332811_EMID1_chr22_29639434_ENST00000404820_length(amino acids)=165AA_BP=1
MFESSPSGDYTTYTTGLTGRFSRAGATLSAEGEIVQMHPLGLCNNNDEEDLYEYGWVGVVKLEQPELDPKPCLTVLGKGEPGPKGDPGEK

--------------------------------------------------------------

>103165_103165_4_ZNRF3-EMID1_ZNRF3_chr22_29383189_ENST00000332811_EMID1_chr22_29650192_ENST00000334018_length(amino acids)=148AA_BP=1
MFESSPSGDYTTYTTGLTGRFSRAGATLSAEGEIVQMHPLGLCNNNDEEDLYEYGWVGVVKLEQPELDPKPCLTVLGKGEGLHQLREALK

--------------------------------------------------------------

>103165_103165_5_ZNRF3-EMID1_ZNRF3_chr22_29383189_ENST00000402174_EMID1_chr22_29639434_ENST00000334018_length(amino acids)=127AA_BP=0
MHPLGLCNNNDEEDLYEYGWVGVVKLEQPELDPKPCLTVLGKGEPGPKGDPGEKSHWGEGLHQLREALKILAERVLILETMIGLYEPELG

--------------------------------------------------------------

>103165_103165_6_ZNRF3-EMID1_ZNRF3_chr22_29383189_ENST00000402174_EMID1_chr22_29639434_ENST00000404755_length(amino acids)=127AA_BP=0
MHPLGLCNNNDEEDLYEYGWVGVVKLEQPELDPKPCLTVLGKGEPGPKGDPGEKSHWGEGLHQLREALKILAERVLILETMIGLYEPELG

--------------------------------------------------------------

>103165_103165_7_ZNRF3-EMID1_ZNRF3_chr22_29383189_ENST00000402174_EMID1_chr22_29639434_ENST00000404820_length(amino acids)=129AA_BP=0
MHPLGLCNNNDEEDLYEYGWVGVVKLEQPELDPKPCLTVLGKGEPGPKGDPGEKSHWAPSLQSFLQQQAQLELLARRVTLLEAIIWPEPE

--------------------------------------------------------------

>103165_103165_8_ZNRF3-EMID1_ZNRF3_chr22_29383189_ENST00000402174_EMID1_chr22_29650192_ENST00000334018_length(amino acids)=112AA_BP=0
MHPLGLCNNNDEEDLYEYGWVGVVKLEQPELDPKPCLTVLGKGEGLHQLREALKILAERVLILETMIGLYEPELGSGAGPAGTGTPSLLR

--------------------------------------------------------------

>103165_103165_9_ZNRF3-EMID1_ZNRF3_chr22_29383189_ENST00000406323_EMID1_chr22_29639434_ENST00000334018_length(amino acids)=127AA_BP=0
MHPLGLCNNNDEEDLYEYGWVGVVKLEQPELDPKPCLTVLGKGEPGPKGDPGEKSHWGEGLHQLREALKILAERVLILETMIGLYEPELG

--------------------------------------------------------------

>103165_103165_10_ZNRF3-EMID1_ZNRF3_chr22_29383189_ENST00000406323_EMID1_chr22_29639434_ENST00000404755_length(amino acids)=127AA_BP=0
MHPLGLCNNNDEEDLYEYGWVGVVKLEQPELDPKPCLTVLGKGEPGPKGDPGEKSHWGEGLHQLREALKILAERVLILETMIGLYEPELG

--------------------------------------------------------------

>103165_103165_11_ZNRF3-EMID1_ZNRF3_chr22_29383189_ENST00000406323_EMID1_chr22_29639434_ENST00000404820_length(amino acids)=129AA_BP=0
MHPLGLCNNNDEEDLYEYGWVGVVKLEQPELDPKPCLTVLGKGEPGPKGDPGEKSHWAPSLQSFLQQQAQLELLARRVTLLEAIIWPEPE

--------------------------------------------------------------

>103165_103165_12_ZNRF3-EMID1_ZNRF3_chr22_29383189_ENST00000406323_EMID1_chr22_29650192_ENST00000334018_length(amino acids)=112AA_BP=0
MHPLGLCNNNDEEDLYEYGWVGVVKLEQPELDPKPCLTVLGKGEGLHQLREALKILAERVLILETMIGLYEPELGSGAGPAGTGTPSLLR

--------------------------------------------------------------

>103165_103165_13_ZNRF3-EMID1_ZNRF3_chr22_29383189_ENST00000544604_EMID1_chr22_29639434_ENST00000334018_length(amino acids)=227AA_BP=0
MRPRSGGRPGATGRRRRRLRRRPRGLRCSRLPPPPPLPLLLGLLLAAAGPGAARAKETAFVEVVLFESSPSGDYTTYTTGLTGRFSRAGA
TLSAEGEIVQMHPLGLCNNNDEEDLYEYGWVGVVKLEQPELDPKPCLTVLGKGEPGPKGDPGEKSHWGEGLHQLREALKILAERVLILET

--------------------------------------------------------------

>103165_103165_14_ZNRF3-EMID1_ZNRF3_chr22_29383189_ENST00000544604_EMID1_chr22_29639434_ENST00000404755_length(amino acids)=227AA_BP=0
MRPRSGGRPGATGRRRRRLRRRPRGLRCSRLPPPPPLPLLLGLLLAAAGPGAARAKETAFVEVVLFESSPSGDYTTYTTGLTGRFSRAGA
TLSAEGEIVQMHPLGLCNNNDEEDLYEYGWVGVVKLEQPELDPKPCLTVLGKGEPGPKGDPGEKSHWGEGLHQLREALKILAERVLILET

--------------------------------------------------------------

>103165_103165_15_ZNRF3-EMID1_ZNRF3_chr22_29383189_ENST00000544604_EMID1_chr22_29639434_ENST00000404820_length(amino acids)=229AA_BP=0
MRPRSGGRPGATGRRRRRLRRRPRGLRCSRLPPPPPLPLLLGLLLAAAGPGAARAKETAFVEVVLFESSPSGDYTTYTTGLTGRFSRAGA
TLSAEGEIVQMHPLGLCNNNDEEDLYEYGWVGVVKLEQPELDPKPCLTVLGKGEPGPKGDPGEKSHWAPSLQSFLQQQAQLELLARRVTL

--------------------------------------------------------------

>103165_103165_16_ZNRF3-EMID1_ZNRF3_chr22_29383189_ENST00000544604_EMID1_chr22_29650192_ENST00000334018_length(amino acids)=212AA_BP=0
MRPRSGGRPGATGRRRRRLRRRPRGLRCSRLPPPPPLPLLLGLLLAAAGPGAARAKETAFVEVVLFESSPSGDYTTYTTGLTGRFSRAGA
TLSAEGEIVQMHPLGLCNNNDEEDLYEYGWVGVVKLEQPELDPKPCLTVLGKGEGLHQLREALKILAERVLILETMIGLYEPELGSGAGP

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Fusion Protein Functional Features


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr22:29280054/chr22:29610914)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.EMID1

Q96A84

FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

* Minus value of BPloci means that the break pointn is located before the CDS.
- Retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- Not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneZNRF3chr22:29383189chr22:29639434ENST00000332811+29241_93642.0837.0Topological domainCytoplasmic
HgeneZNRF3chr22:29383189chr22:29639434ENST00000332811+2956_21942.0837.0Topological domainExtracellular
HgeneZNRF3chr22:29383189chr22:29639434ENST00000402174+29241_93642.0837.0Topological domainCytoplasmic
HgeneZNRF3chr22:29383189chr22:29639434ENST00000402174+2956_21942.0837.0Topological domainExtracellular
HgeneZNRF3chr22:29383189chr22:29639434ENST00000406323+18241_93642.0837.0Topological domainCytoplasmic
HgeneZNRF3chr22:29383189chr22:29639434ENST00000406323+1856_21942.0837.0Topological domainExtracellular
HgeneZNRF3chr22:29383189chr22:29639434ENST00000544604+29241_936142.0937.0Topological domainCytoplasmic
HgeneZNRF3chr22:29383189chr22:29639434ENST00000544604+2956_219142.0937.0Topological domainExtracellular
HgeneZNRF3chr22:29383189chr22:29650192ENST00000332811+29241_93642.0837.0Topological domainCytoplasmic
HgeneZNRF3chr22:29383189chr22:29650192ENST00000332811+2956_21942.0837.0Topological domainExtracellular
HgeneZNRF3chr22:29383189chr22:29650192ENST00000402174+29241_93642.0837.0Topological domainCytoplasmic
HgeneZNRF3chr22:29383189chr22:29650192ENST00000402174+2956_21942.0837.0Topological domainExtracellular
HgeneZNRF3chr22:29383189chr22:29650192ENST00000406323+18241_93642.0837.0Topological domainCytoplasmic
HgeneZNRF3chr22:29383189chr22:29650192ENST00000406323+1856_21942.0837.0Topological domainExtracellular
HgeneZNRF3chr22:29383189chr22:29650192ENST00000544604+29241_936142.0937.0Topological domainCytoplasmic
HgeneZNRF3chr22:29383189chr22:29650192ENST00000544604+2956_219142.0937.0Topological domainExtracellular
HgeneZNRF3chr22:29383189chr22:29639434ENST00000332811+29220_24042.0837.0TransmembraneHelical
HgeneZNRF3chr22:29383189chr22:29639434ENST00000402174+29220_24042.0837.0TransmembraneHelical
HgeneZNRF3chr22:29383189chr22:29639434ENST00000406323+18220_24042.0837.0TransmembraneHelical
HgeneZNRF3chr22:29383189chr22:29639434ENST00000544604+29220_240142.0937.0TransmembraneHelical
HgeneZNRF3chr22:29383189chr22:29650192ENST00000332811+29220_24042.0837.0TransmembraneHelical
HgeneZNRF3chr22:29383189chr22:29650192ENST00000402174+29220_24042.0837.0TransmembraneHelical
HgeneZNRF3chr22:29383189chr22:29650192ENST00000406323+18220_24042.0837.0TransmembraneHelical
HgeneZNRF3chr22:29383189chr22:29650192ENST00000544604+29220_240142.0937.0TransmembraneHelical
HgeneZNRF3chr22:29383189chr22:29639434ENST00000332811+29293_33442.0837.0Zinc fingerRING-type%3B atypical
HgeneZNRF3chr22:29383189chr22:29639434ENST00000402174+29293_33442.0837.0Zinc fingerRING-type%3B atypical
HgeneZNRF3chr22:29383189chr22:29639434ENST00000406323+18293_33442.0837.0Zinc fingerRING-type%3B atypical
HgeneZNRF3chr22:29383189chr22:29639434ENST00000544604+29293_334142.0937.0Zinc fingerRING-type%3B atypical
HgeneZNRF3chr22:29383189chr22:29650192ENST00000332811+29293_33442.0837.0Zinc fingerRING-type%3B atypical
HgeneZNRF3chr22:29383189chr22:29650192ENST00000402174+29293_33442.0837.0Zinc fingerRING-type%3B atypical
HgeneZNRF3chr22:29383189chr22:29650192ENST00000406323+18293_33442.0837.0Zinc fingerRING-type%3B atypical
HgeneZNRF3chr22:29383189chr22:29650192ENST00000544604+29293_334142.0937.0Zinc fingerRING-type%3B atypical
TgeneEMID1chr22:29383189chr22:29639434ENST000003340181115179_368358.0444.0DomainNote=Collagen-like
TgeneEMID1chr22:29383189chr22:29639434ENST00000334018111533_106358.0444.0DomainEMI
TgeneEMID1chr22:29383189chr22:29650192ENST000003340181215179_368373.0444.0DomainNote=Collagen-like
TgeneEMID1chr22:29383189chr22:29650192ENST00000334018121533_106373.0444.0DomainEMI


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Fusion Protein-Protein Interaction


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type from validated records (BIOGRID-3.4.160)
GenePPI interactors


check button Protein-protein interactors based on sequence similarity (STRING)
GeneSTRING network
ZNRF3
EMID1


check button - Retained interactions in fusion protein (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost interactions due to fusion (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs to ZNRF3-EMID1


check button Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDrugSourcePMID

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Related Diseases to ZNRF3-EMID1


check button Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDiseaseSourcePMID

check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource