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	Fusion Gene Summary
	Fusion Gene Sample Information
	Fusion ORF Analysis
	Fusion Amino Acid Sequences
	Fusion Protein Functional Features
	Fusion Protein Structure
	pLDDT scores
	Ramachandran Plot of Fusion Protein Structure
	Fusion Protein-Protein Interaction
	Related drugs with this fusion protein
	Related disease with this fusion protein

Fusion Protein:BTBD2-OAS2

Fusion Protein Summary

Fusion gene summary

Fusion partner gene information	Fusion gene name: BTBD2-OAS2
	FusionPDB ID: 10461
	FusionGDB2.0 ID: 10461
		Hgene	Tgene
	Gene symbol	BTBD2	OAS2
	Gene ID	55643	4939
	Gene name	BTB domain containing 2	2'-5'-oligoadenylate synthetase 2
	Synonyms	-	-
	Cytomap	19p13.3	12q24.13
	Type of gene	protein-coding	protein-coding
	Description	BTB/POZ domain-containing protein 2BTB (POZ) domain containing 2	2'-5'-oligoadenylate synthase 2(2'-5')oligo(A) synthetase 22'-5'-oligoadenylate synthetase 2, 69/71kDa2-5A synthase 2p69 OAS / p71 OAS
	Modification date	20200327	20200313
	UniProtAcc	Q9BX70	.
Ensembl transtripts involved in fusion gene	ENST ids	ENST00000255608, ENST00000590646,	ENST00000449768, ENST00000342315, ENST00000392583,
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)	* DoF score	13 X 11 X 11=1573	4 X 4 X 4=64
	# samples	18	5
	** MAII score	log2(18/1573*10)=-3.12744985908601 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(5/64*10)=-0.356143810225275 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context (manual curation of fusion genes in FusionPDB)	PubMed: BTBD2 [Title/Abstract] AND OAS2 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)	BTBD2(1993019)-OAS2(113424843), # samples:3
Anticipated loss of major functional domain due to fusion event.	BTBD2-OAS2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. BTBD2-OAS2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. BTBD2-OAS2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. BTBD2-OAS2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. BTBD2-OAS2 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner

Gene

GO ID

GO term

PubMed ID

Fusion gene breakpoints across BTBD2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across OAS2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

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Fusion Gene Sample Information

Fusion gene information from FusionGDB2.0.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	LGG	TCGA-FG-A4MU-01B	BTBD2	chr19	1993018	-	OAS2	chr12	113424842	+
ChimerDB4	LGG	TCGA-FG-A4MU-01B	BTBD2	chr19	1993019	-	OAS2	chr12	113424843	+
ChimerDB4	LGG	TCGA-FG-A4MU	BTBD2	chr19	1993018	-	OAS2	chr12	113424842	+
ChimerDB4	LGG	TCGA-FG-A4MU	BTBD2	chr19	1993019	-	OAS2	chr12	113424843	+

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Fusion ORF Analysis

Fusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000255608	BTBD2	chr19	1993019	-	ENST00000342315	OAS2	chr12	113424843	+	3923	701	17	2683	888
ENST00000255608	BTBD2	chr19	1993019	-	ENST00000392583	OAS2	chr12	113424843	+	5051	701	17	2587	856
ENST00000255608	BTBD2	chr19	1993018	-	ENST00000342315	OAS2	chr12	113424842	+	3923	701	17	2683	888
ENST00000255608	BTBD2	chr19	1993018	-	ENST00000392583	OAS2	chr12	113424842	+	5051	701	17	2587	856

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000255608	ENST00000342315	BTBD2	chr19	1993019	-	OAS2	chr12	113424843	+	0.001481597	0.9985184
ENST00000255608	ENST00000392583	BTBD2	chr19	1993019	-	OAS2	chr12	113424843	+	0.001092616	0.9989073
ENST00000255608	ENST00000342315	BTBD2	chr19	1993018	-	OAS2	chr12	113424842	+	0.001481597	0.9985184
ENST00000255608	ENST00000392583	BTBD2	chr19	1993018	-	OAS2	chr12	113424842	+	0.001092616	0.9989073

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Fusion Amino Acid Sequences

For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

>10461_10461_1_BTBD2-OAS2_BTBD2_chr19_1993018_ENST00000255608_OAS2_chr12_113424842_ENST00000342315_length(amino acids)=888AA_BP=562
MAAGGSGGRASCPPGVGVGPGTGGSPGPSANAAATPAPGNAAAAAAAAAAAAAAPGPTPPAPPGPGTDAQAAGAERAEEAAGPGAAALQR
EAAYNWQASKPTVQERFAFLFNNEVLCDVHFLVGKGLSSQRIPAHRFVLAVGSAVFDAMFNGGMATTSTEIELPDVEPAAFLALLKFLYS
DEVQIGPETVMTTLYTAKKYAVPALEAHCVEFLKKNLRADNAFMLLTQGGSYGRKTVLRGNSDGTLVLFFSDLKQFQDQKRSQRDILDKT
GDKLKFCLFTKWLKNNFEIQKSLDGFTIQVFTKNQRISFEVLAAFNALSLNDNPSPWIYRELKRSLDKTNASPGEFAVCFTELQQKFFDN
RPGKLKDLILLIKHWHQQCQKKIKDLPSLSPYALELLTVYAWEQGCRKDNFDIAEGVRTVLELIKCQEKLCIYWMVNYNFEDETIRNILL
HQLQSARPVILDPVDPTNNVSGDKICWQWLKKEAQTWLTSPNLDNELPAPSWNVLPAPLFTTPGHLLDKFIKEFLQPNKCFLEQIDSAVN
IIRTFLKENCFRQSTAKIQIVRGGSTAKGTALKTGSDADLVVFHNSLKSYTSQKNERHKIVKEIHEQLKAFWREKEEELEVSFEPPKWKA
PRVLSFSLKSKVLNESVSFDVLPAFNALGQLSSGSTPSPEVYAGLIDLYKSSDLPGGEFSTCFTVLQRNFIRSRPTKLKDLIRLVKHWYK
ECERKLKPKGSLPPKYALELLTIYAWEQGSGVPDFDTAEGFRTVLELVTQYQQLCIFWKVNYNFEDETVRKFLLSQLQKTRPVILDPAEP

--------------------------------------------------------------

>10461_10461_2_BTBD2-OAS2_BTBD2_chr19_1993018_ENST00000255608_OAS2_chr12_113424842_ENST00000392583_length(amino acids)=856AA_BP=562
MAAGGSGGRASCPPGVGVGPGTGGSPGPSANAAATPAPGNAAAAAAAAAAAAAAPGPTPPAPPGPGTDAQAAGAERAEEAAGPGAAALQR
EAAYNWQASKPTVQERFAFLFNNEVLCDVHFLVGKGLSSQRIPAHRFVLAVGSAVFDAMFNGGMATTSTEIELPDVEPAAFLALLKFLYS
DEVQIGPETVMTTLYTAKKYAVPALEAHCVEFLKKNLRADNAFMLLTQGGSYGRKTVLRGNSDGTLVLFFSDLKQFQDQKRSQRDILDKT
GDKLKFCLFTKWLKNNFEIQKSLDGFTIQVFTKNQRISFEVLAAFNALSLNDNPSPWIYRELKRSLDKTNASPGEFAVCFTELQQKFFDN
RPGKLKDLILLIKHWHQQCQKKIKDLPSLSPYALELLTVYAWEQGCRKDNFDIAEGVRTVLELIKCQEKLCIYWMVNYNFEDETIRNILL
HQLQSARPVILDPVDPTNNVSGDKICWQWLKKEAQTWLTSPNLDNELPAPSWNVLPAPLFTTPGHLLDKFIKEFLQPNKCFLEQIDSAVN
IIRTFLKENCFRQSTAKIQIVRGGSTAKGTALKTGSDADLVVFHNSLKSYTSQKNERHKIVKEIHEQLKAFWREKEEELEVSFEPPKWKA
PRVLSFSLKSKVLNESVSFDVLPAFNALGQLSSGSTPSPEVYAGLIDLYKSSDLPGGEFSTCFTVLQRNFIRSRPTKLKDLIRLVKHWYK
ECERKLKPKGSLPPKYALELLTIYAWEQGSGVPDFDTAEGFRTVLELVTQYQQLCIFWKVNYNFEDETVRKFLLSQLQKTRPVILDPAEP

--------------------------------------------------------------

>10461_10461_3_BTBD2-OAS2_BTBD2_chr19_1993019_ENST00000255608_OAS2_chr12_113424843_ENST00000342315_length(amino acids)=888AA_BP=562
MAAGGSGGRASCPPGVGVGPGTGGSPGPSANAAATPAPGNAAAAAAAAAAAAAAPGPTPPAPPGPGTDAQAAGAERAEEAAGPGAAALQR
EAAYNWQASKPTVQERFAFLFNNEVLCDVHFLVGKGLSSQRIPAHRFVLAVGSAVFDAMFNGGMATTSTEIELPDVEPAAFLALLKFLYS
DEVQIGPETVMTTLYTAKKYAVPALEAHCVEFLKKNLRADNAFMLLTQGGSYGRKTVLRGNSDGTLVLFFSDLKQFQDQKRSQRDILDKT
GDKLKFCLFTKWLKNNFEIQKSLDGFTIQVFTKNQRISFEVLAAFNALSLNDNPSPWIYRELKRSLDKTNASPGEFAVCFTELQQKFFDN
RPGKLKDLILLIKHWHQQCQKKIKDLPSLSPYALELLTVYAWEQGCRKDNFDIAEGVRTVLELIKCQEKLCIYWMVNYNFEDETIRNILL
HQLQSARPVILDPVDPTNNVSGDKICWQWLKKEAQTWLTSPNLDNELPAPSWNVLPAPLFTTPGHLLDKFIKEFLQPNKCFLEQIDSAVN
IIRTFLKENCFRQSTAKIQIVRGGSTAKGTALKTGSDADLVVFHNSLKSYTSQKNERHKIVKEIHEQLKAFWREKEEELEVSFEPPKWKA
PRVLSFSLKSKVLNESVSFDVLPAFNALGQLSSGSTPSPEVYAGLIDLYKSSDLPGGEFSTCFTVLQRNFIRSRPTKLKDLIRLVKHWYK
ECERKLKPKGSLPPKYALELLTIYAWEQGSGVPDFDTAEGFRTVLELVTQYQQLCIFWKVNYNFEDETVRKFLLSQLQKTRPVILDPAEP

--------------------------------------------------------------

>10461_10461_4_BTBD2-OAS2_BTBD2_chr19_1993019_ENST00000255608_OAS2_chr12_113424843_ENST00000392583_length(amino acids)=856AA_BP=562
MAAGGSGGRASCPPGVGVGPGTGGSPGPSANAAATPAPGNAAAAAAAAAAAAAAPGPTPPAPPGPGTDAQAAGAERAEEAAGPGAAALQR
EAAYNWQASKPTVQERFAFLFNNEVLCDVHFLVGKGLSSQRIPAHRFVLAVGSAVFDAMFNGGMATTSTEIELPDVEPAAFLALLKFLYS
DEVQIGPETVMTTLYTAKKYAVPALEAHCVEFLKKNLRADNAFMLLTQGGSYGRKTVLRGNSDGTLVLFFSDLKQFQDQKRSQRDILDKT
GDKLKFCLFTKWLKNNFEIQKSLDGFTIQVFTKNQRISFEVLAAFNALSLNDNPSPWIYRELKRSLDKTNASPGEFAVCFTELQQKFFDN
RPGKLKDLILLIKHWHQQCQKKIKDLPSLSPYALELLTVYAWEQGCRKDNFDIAEGVRTVLELIKCQEKLCIYWMVNYNFEDETIRNILL
HQLQSARPVILDPVDPTNNVSGDKICWQWLKKEAQTWLTSPNLDNELPAPSWNVLPAPLFTTPGHLLDKFIKEFLQPNKCFLEQIDSAVN
IIRTFLKENCFRQSTAKIQIVRGGSTAKGTALKTGSDADLVVFHNSLKSYTSQKNERHKIVKEIHEQLKAFWREKEEELEVSFEPPKWKA
PRVLSFSLKSKVLNESVSFDVLPAFNALGQLSSGSTPSPEVYAGLIDLYKSSDLPGGEFSTCFTVLQRNFIRSRPTKLKDLIRLVKHWYK
ECERKLKPKGSLPPKYALELLTIYAWEQGSGVPDFDTAEGFRTVLELVTQYQQLCIFWKVNYNFEDETVRKFLLSQLQKTRPVILDPAEP

--------------------------------------------------------------

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Fusion Protein Functional Features

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr19:1993019/chr12:113424843)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
BTBD2 Q9BX70	.
	FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page
* Minus value of BPloci means that the break pointn is located before the CDS.

- Retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

BTBD2

chr19:1993018

chr12:113424842

ENST00000255608

41_54

228.0

526.0

Compositional bias

Note=Poly-Ala

Hgene

BTBD2

chr19:1993019

chr12:113424843

ENST00000255608

41_54

228.0

526.0

Compositional bias

Note=Poly-Ala

Hgene

BTBD2

chr19:1993018

chr12:113424842

ENST00000255608

117_187

228.0

526.0

Domain

BTB

Hgene

BTBD2

chr19:1993019

chr12:113424843

ENST00000255608

117_187

228.0

526.0

Domain

BTB

Tgene

OAS2

chr19:1993018

chr12:113424842

ENST00000342315

326_346

59.0

720.0

Compositional bias

Note=Pro-rich (linker)

Tgene

OAS2

chr19:1993018

chr12:113424842

ENST00000392583

326_346

59.0

688.0

Compositional bias

Note=Pro-rich (linker)

Tgene

OAS2

chr19:1993018

chr12:113424842

ENST00000449768

326_346

59.0

173.0

Compositional bias

Note=Pro-rich (linker)

Tgene

OAS2

chr19:1993019

chr12:113424843

ENST00000342315

326_346

59.0

720.0

Compositional bias

Note=Pro-rich (linker)

Tgene

OAS2

chr19:1993019

chr12:113424843

ENST00000392583

326_346

59.0

688.0

Compositional bias

Note=Pro-rich (linker)

Tgene

OAS2

chr19:1993019

chr12:113424843

ENST00000449768

326_346

59.0

173.0

Compositional bias

Note=Pro-rich (linker)

Tgene

OAS2

chr19:1993018

chr12:113424842

ENST00000342315

343_683

59.0

720.0

Region

Note=OAS domain 2

Tgene

OAS2

chr19:1993018

chr12:113424842

ENST00000392583

343_683

59.0

688.0

Region

Note=OAS domain 2

Tgene

OAS2

chr19:1993018

chr12:113424842

ENST00000449768

343_683

59.0

173.0

Region

Note=OAS domain 2

Tgene

OAS2

chr19:1993019

chr12:113424843

ENST00000342315

343_683

59.0

720.0

Region

Note=OAS domain 2

Tgene

OAS2

chr19:1993019

chr12:113424843

ENST00000392583

343_683

59.0

688.0

Region

Note=OAS domain 2

Tgene

OAS2

chr19:1993019

chr12:113424843

ENST00000449768

343_683

59.0

173.0

Region

Note=OAS domain 2

- Not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Tgene

OAS2

chr19:1993018

chr12:113424842

ENST00000342315

11_335

59.0

720.0

Region

Note=OAS domain 1

Tgene

OAS2

chr19:1993018

chr12:113424842

ENST00000392583

11_335

59.0

688.0

Region

Note=OAS domain 1

Tgene

OAS2

chr19:1993018

chr12:113424842

ENST00000449768

11_335

59.0

173.0

Region

Note=OAS domain 1

Tgene

OAS2

chr19:1993019

chr12:113424843

ENST00000342315

11_335

59.0

720.0

Region

Note=OAS domain 1

Tgene

OAS2

chr19:1993019

chr12:113424843

ENST00000392583

11_335

59.0

688.0

Region

Note=OAS domain 1

Tgene

OAS2

chr19:1993019

chr12:113424843

ENST00000449768

11_335

59.0

173.0

Region

Note=OAS domain 1

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Fusion Protein Structures

PDB and CIF files of the predicted fusion proteins
* Here we show the 3D structure of the fusion proteins using Mol*. AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Model confidence is shown from the pLDDT values per residue. pLDDT corresponds to the model’s prediction of its score on the local Distance Difference Test. It is a measure of local accuracy (from AlphfaFold website). To color code individual residues, we transformed individual PDB files into CIF format.

Fusion protein PDB link (fusion AA seq ID in FusionPDB)	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	AA seq	Len(AA seq)
PDB file >>>1680_BTBD2_1993019_OAS2_113424843_ranked_0.pdb	BTBD2	1993018	1993019	ENST00000392583	OAS2	chr12	113424843	+	MAAGGSGGRASCPPGVGVGPGTGGSPGPSANAAATPAPGNAAAAAAAAAAAAAAPGPTPPAPPGPGTDAQAAGAERAEEAAGPGAAALQR EAAYNWQASKPTVQERFAFLFNNEVLCDVHFLVGKGLSSQRIPAHRFVLAVGSAVFDAMFNGGMATTSTEIELPDVEPAAFLALLKFLYS DEVQIGPETVMTTLYTAKKYAVPALEAHCVEFLKKNLRADNAFMLLTQGGSYGRKTVLRGNSDGTLVLFFSDLKQFQDQKRSQRDILDKT GDKLKFCLFTKWLKNNFEIQKSLDGFTIQVFTKNQRISFEVLAAFNALSLNDNPSPWIYRELKRSLDKTNASPGEFAVCFTELQQKFFDN RPGKLKDLILLIKHWHQQCQKKIKDLPSLSPYALELLTVYAWEQGCRKDNFDIAEGVRTVLELIKCQEKLCIYWMVNYNFEDETIRNILL HQLQSARPVILDPVDPTNNVSGDKICWQWLKKEAQTWLTSPNLDNELPAPSWNVLPAPLFTTPGHLLDKFIKEFLQPNKCFLEQIDSAVN IIRTFLKENCFRQSTAKIQIVRGGSTAKGTALKTGSDADLVVFHNSLKSYTSQKNERHKIVKEIHEQLKAFWREKEEELEVSFEPPKWKA PRVLSFSLKSKVLNESVSFDVLPAFNALGQLSSGSTPSPEVYAGLIDLYKSSDLPGGEFSTCFTVLQRNFIRSRPTKLKDLIRLVKHWYK ECERKLKPKGSLPPKYALELLTIYAWEQGSGVPDFDTAEGFRTVLELVTQYQQLCIFWKVNYNFEDETVRKFLLSQLQKTRPVILDPAEP	888

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pLDDT score distribution

pLDDT score distribution of the predicted wild-type structures of two partner proteins from AlphaFold2
* AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100.

BTBD2_pLDDT.png

OAS2_pLDDT.png

pLDDT score distribution of the predicted fusion protein structures from AlphaFold2
* AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100.

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Ramachandran Plot of Fusion Protein Structure

Ramachandran plot of the torsional angles - phi (φ)and psi (ψ) - of the residues (amino acids) contained in this fusion protein peptide.

Fusion AA seq ID in FusionPDB and their Ramachandran plots

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Fusion Protein-Protein Interaction

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type from validated records (BIOGRID-3.4.160)

Gene

PPI interactors

Protein-protein interactors based on sequence similarity (STRING)

Gene	STRING network
BTBD2
OAS2

- Retained interactions in fusion protein (protein functional feature from UniProt).

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost interactions due to fusion (protein functional feature from UniProt).

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

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Related Drugs to BTBD2-OAS2

Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)

Hgene

Tgene

Drug

Source

PMID

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Related Diseases to BTBD2-OAS2

Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)

Hgene

Tgene

Disease

Source

PMID

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source