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Center for Computational Systems Medicine level1
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Fusion Gene Summary

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Fusion Gene Sample Information

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Fusion ORF Analysis

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Fusion Amino Acid Sequences

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Fusion Protein Functional Features

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Fusion Protein-Protein Interaction

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Related drugs with this fusion protein

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Related disease with this fusion protein

Fusion Protein:CDKN2A-EXD2

Fusion Protein Summary

check button Fusion gene summary
Fusion partner gene informationFusion gene name: CDKN2A-EXD2
FusionPDB ID: 15399
FusionGDB2.0 ID: 15399
HgeneTgene
Gene symbol

CDKN2A

EXD2

Gene ID

1029

55218

Gene namecyclin dependent kinase inhibitor 2Aexonuclease 3'-5' domain containing 2
SynonymsARF|CDK4I|CDKN2|CMM2|INK4|INK4A|MLM|MTS-1|MTS1|P14|P14ARF|P16|P16-INK4A|P16INK4|P16INK4A|P19|P19ARF|TP16C14orf114|EXDL2
Cytomap

9p21.3

14q24.1

Type of geneprotein-codingprotein-coding
Descriptioncyclin-dependent kinase inhibitor 2ACDK4 inhibitor p16-INK4alternative reading framecell cycle negative regulator betacyclin-dependent kinase 4 inhibitor Acyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)multiple tumor suppressor 1exonuclease 3'-5' domain-containing protein 23'-5' exoribonuclease EXD2exonuclease 3'-5' domain-like 2exonuclease 3'-5' domain-like-containing protein 2
Modification date2020032920200313
UniProtAcc

Q96HQ2

Q9NVH0

Ensembl transtripts involved in fusion geneENST idsENST00000304494, ENST00000446177, 
ENST00000498124, ENST00000579122, 
ENST00000361570, ENST00000470819, 
ENST00000479692, ENST00000494262, 
ENST00000497750, ENST00000498628, 
ENST00000530628, ENST00000578845, 
ENST00000579755, 		ENST00000492815, 
ENST00000312994, ENST00000409014, 
ENST00000409242, ENST00000409675, 
ENST00000409949, ENST00000449989, 
ENST00000409018, 
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)* DoF score14 X 9 X 11=13865 X 5 X 3=75
# samples 176
** MAII scorelog2(17/1386*10)=-3.02732060599951
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(6/75*10)=-0.321928094887362
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context (manual curation of fusion genes in FusionPDB)

PubMed: CDKN2A [Title/Abstract] AND EXD2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)CDKN2A(21974677)-EXD2(69695533), # samples:2
Anticipated loss of major functional domain due to fusion event.CDKN2A-EXD2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
CDKN2A-EXD2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
CDKN2A-EXD2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
CDKN2A-EXD2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneCDKN2A

GO:0000082

G1/S transition of mitotic cell cycle

10208428

HgeneCDKN2A

GO:0007050

cell cycle arrest

15149599

HgeneCDKN2A

GO:0008285

negative regulation of cell proliferation

15149599

HgeneCDKN2A

GO:0030308

negative regulation of cell growth

10208428

HgeneCDKN2A

GO:0032088

negative regulation of NF-kappaB transcription factor activity

10353611

HgeneCDKN2A

GO:0042326

negative regulation of phosphorylation

8259215|10208428

HgeneCDKN2A

GO:0045736

negative regulation of cyclin-dependent protein serine/threonine kinase activity

7739547|8259215

TgeneEXD2

GO:0000724

double-strand break repair via homologous recombination

26807646

TgeneEXD2

GO:0000729

DNA double-strand break processing

26807646

TgeneEXD2

GO:0006302

double-strand break repair

26807646

TgeneEXD2

GO:0090305

nucleic acid phosphodiester bond hydrolysis

26807646


check buttonFusion gene breakpoints across CDKN2A (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across EXD2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure


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Fusion Gene Sample Information

check buttonFusion gene information from FusionGDB2.0.
check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BLCATCGA-XF-AAMW-01ACDKN2Achr9

21974677

-EXD2chr14

69695533

+


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Fusion ORF Analysis


check buttonFusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000304494CDKN2Achr921974677-ENST00000409018EXD2chr1469695533+32124211241953609
ENST00000579122CDKN2Achr921974677-ENST00000409018EXD2chr1469695533+2972181311713560
ENST00000498124CDKN2Achr921974677-ENST00000409018EXD2chr1469695533+2980189391721560
ENST00000446177CDKN2Achr921974677-ENST00000409018EXD2chr1469695533+3153362651894609

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000304494ENST00000409018CDKN2Achr921974677-EXD2chr1469695533+0.0018882860.9981117
ENST00000579122ENST00000409018CDKN2Achr921974677-EXD2chr1469695533+0.0018372310.9981628
ENST00000498124ENST00000409018CDKN2Achr921974677-EXD2chr1469695533+0.0017961220.9982039
ENST00000446177ENST00000409018CDKN2Achr921974677-EXD2chr1469695533+0.0019056610.9980944

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Fusion Amino Acid Sequences


check button For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

>15399_15399_1_CDKN2A-EXD2_CDKN2A_chr9_21974677_ENST00000304494_EXD2_chr14_69695533_ENST00000409018_length(amino acids)=609AA_BP=98
MRDRVGGGSSASTGGRKRRGWLVTRGWGGPRALGGCGEGESRQRAAGSSMEPAAGSSMEPSADWLATAAARGRVEEVRALLEAGALPNAP
NSYGRRPIQVNLEGKASPLSLLQMASPSGLCVLVRLPKLICGGKTLPRTLLDILADGTILKVGVGCSEDASKLLQDYGLVVRGCLDLRYL
AMRQRNNLLCNGLSLKSLAETVLNFPLDKSLLLRCSNWDAETLTEDQVIYAARDAQISVALFLHLLGYPFSRNSPGEKNDDHSSWRKVLE
KCQGVVDIPFRSKGMSRLGEEVNGEATESQQKPRNKKSKMDGMVPGNHQGRDPRKHKRKPLGVGYSARKSPLYDNCFLHAPDGQPLCTCD
RRKAQWYLDKGIGELVSEEPFVVKLRFEPAGRPESPGDYYLMVKENLCVVCGKRDSYIRKNVIPHEYRKHFPIEMKDHNSHDVLLLCTSC
HAISNYYDNHLKQQLAKEFQAPIGSEEGLRLLEDPERRQVRSGARALLNAESLPTQRKEELLQALREFYNTDVVTEEMLQEAASLETRIS

--------------------------------------------------------------

>15399_15399_2_CDKN2A-EXD2_CDKN2A_chr9_21974677_ENST00000446177_EXD2_chr14_69695533_ENST00000409018_length(amino acids)=609AA_BP=98
MRDRVGGGSSASTGGRKRRGWLVTRGWGGPRALGGCGEGESRQRAAGSSMEPAAGSSMEPSADWLATAAARGRVEEVRALLEAGALPNAP
NSYGRRPIQVNLEGKASPLSLLQMASPSGLCVLVRLPKLICGGKTLPRTLLDILADGTILKVGVGCSEDASKLLQDYGLVVRGCLDLRYL
AMRQRNNLLCNGLSLKSLAETVLNFPLDKSLLLRCSNWDAETLTEDQVIYAARDAQISVALFLHLLGYPFSRNSPGEKNDDHSSWRKVLE
KCQGVVDIPFRSKGMSRLGEEVNGEATESQQKPRNKKSKMDGMVPGNHQGRDPRKHKRKPLGVGYSARKSPLYDNCFLHAPDGQPLCTCD
RRKAQWYLDKGIGELVSEEPFVVKLRFEPAGRPESPGDYYLMVKENLCVVCGKRDSYIRKNVIPHEYRKHFPIEMKDHNSHDVLLLCTSC
HAISNYYDNHLKQQLAKEFQAPIGSEEGLRLLEDPERRQVRSGARALLNAESLPTQRKEELLQALREFYNTDVVTEEMLQEAASLETRIS

--------------------------------------------------------------

>15399_15399_3_CDKN2A-EXD2_CDKN2A_chr9_21974677_ENST00000498124_EXD2_chr14_69695533_ENST00000409018_length(amino acids)=560AA_BP=49
MEPAAGSSMEPSADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVNLEGKASPLSLLQMASPSGLCVLVRLPKLICGGKTLPRT
LLDILADGTILKVGVGCSEDASKLLQDYGLVVRGCLDLRYLAMRQRNNLLCNGLSLKSLAETVLNFPLDKSLLLRCSNWDAETLTEDQVI
YAARDAQISVALFLHLLGYPFSRNSPGEKNDDHSSWRKVLEKCQGVVDIPFRSKGMSRLGEEVNGEATESQQKPRNKKSKMDGMVPGNHQ
GRDPRKHKRKPLGVGYSARKSPLYDNCFLHAPDGQPLCTCDRRKAQWYLDKGIGELVSEEPFVVKLRFEPAGRPESPGDYYLMVKENLCV
VCGKRDSYIRKNVIPHEYRKHFPIEMKDHNSHDVLLLCTSCHAISNYYDNHLKQQLAKEFQAPIGSEEGLRLLEDPERRQVRSGARALLN
AESLPTQRKEELLQALREFYNTDVVTEEMLQEAASLETRISNENYVPHGLKVVQCHSQGGLRSLMQLESRWRQHFLDSMQPKHLPQQWSV

--------------------------------------------------------------

>15399_15399_4_CDKN2A-EXD2_CDKN2A_chr9_21974677_ENST00000579122_EXD2_chr14_69695533_ENST00000409018_length(amino acids)=560AA_BP=49
MEPAAGSSMEPSADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVNLEGKASPLSLLQMASPSGLCVLVRLPKLICGGKTLPRT
LLDILADGTILKVGVGCSEDASKLLQDYGLVVRGCLDLRYLAMRQRNNLLCNGLSLKSLAETVLNFPLDKSLLLRCSNWDAETLTEDQVI
YAARDAQISVALFLHLLGYPFSRNSPGEKNDDHSSWRKVLEKCQGVVDIPFRSKGMSRLGEEVNGEATESQQKPRNKKSKMDGMVPGNHQ
GRDPRKHKRKPLGVGYSARKSPLYDNCFLHAPDGQPLCTCDRRKAQWYLDKGIGELVSEEPFVVKLRFEPAGRPESPGDYYLMVKENLCV
VCGKRDSYIRKNVIPHEYRKHFPIEMKDHNSHDVLLLCTSCHAISNYYDNHLKQQLAKEFQAPIGSEEGLRLLEDPERRQVRSGARALLN
AESLPTQRKEELLQALREFYNTDVVTEEMLQEAASLETRISNENYVPHGLKVVQCHSQGGLRSLMQLESRWRQHFLDSMQPKHLPQQWSV

--------------------------------------------------------------

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Fusion Protein Functional Features


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr9:21974677/chr14:69695533)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
CDKN2A

Q96HQ2

EXD2

Q9NVH0

FUNCTION: Exonuclease that has both 3'-5' exoribonuclease and exodeoxyribonuclease activities, depending on the divalent metal cation used as cofactor (PubMed:29335528, PubMed:31127291). In presence of Mg(2+), only shows 3'-5' exoribonuclease activity, while it shows both exoribonuclease and exodeoxyribonuclease activities in presence of Mn(2+) (PubMed:29335528, PubMed:31127291). Acts as an exoribonuclease in mitochondrion, possibly by regulating ATP production and mitochondrial translation (PubMed:29335528). Also involved in the response to DNA damage (PubMed:26807646, PubMed:31255466). Acts as 3'-5' exodeoxyribonuclease for double-strand breaks resection and efficient homologous recombination (PubMed:20603073, PubMed:26807646). Plays a key role in controlling the initial steps of chromosomal break repair, it is recruited to chromatin in a damage-dependent manner and functionally interacts with the MRN complex to accelerate resection through its 3'-5' exonuclease activity, which efficiently processes double-stranded DNA substrates containing nicks (PubMed:26807646). Also involved in response to replicative stress: recruited to stalled forks and is required to stabilize and restart stalled replication forks by restraining excessive fork regression, thereby suppressing their degradation (PubMed:31255466). {ECO:0000269|PubMed:20603073, ECO:0000269|PubMed:26807646, ECO:0000269|PubMed:29335528, ECO:0000269|PubMed:31127291, ECO:0000269|PubMed:31255466}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

* Minus value of BPloci means that the break pointn is located before the CDS.
- Retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCDKN2Achr9:21974677chr14:69695533ENST00000304494-1311_4050.0157.0RepeatNote=ANK 1
HgeneCDKN2Achr9:21974677chr14:69695533ENST00000446177-1311_4050.0168.0RepeatNote=ANK 1
HgeneCDKN2Achr9:21974677chr14:69695533ENST00000498124-1411_4050.0130.66666666666666RepeatNote=ANK 1
TgeneEXD2chr9:21974677chr14:69695533ENST0000031299419155_247111.0622.0Domain3'-5' exonuclease
TgeneEXD2chr9:21974677chr14:69695533ENST00000409014311155_2470497.0Domain3'-5' exonuclease
TgeneEXD2chr9:21974677chr14:69695533ENST0000040901819155_247111.0622.0Domain3'-5' exonuclease
TgeneEXD2chr9:21974677chr14:69695533ENST0000040924219155_2470497.0Domain3'-5' exonuclease
TgeneEXD2chr9:21974677chr14:69695533ENST0000040967508155_2470497.0Domain3'-5' exonuclease
TgeneEXD2chr9:21974677chr14:69695533ENST00000409949210155_2470497.0Domain3'-5' exonuclease
TgeneEXD2chr9:21974677chr14:69695533ENST0000044998908155_2470497.0Domain3'-5' exonuclease
TgeneEXD2chr9:21974677chr14:69695533ENST000004090143111_40497.0Topological domainMitochondrial intermembrane
TgeneEXD2chr9:21974677chr14:69695533ENST0000040901431126_6210497.0Topological domainCytoplasmic
TgeneEXD2chr9:21974677chr14:69695533ENST00000409242191_40497.0Topological domainMitochondrial intermembrane
TgeneEXD2chr9:21974677chr14:69695533ENST000004092421926_6210497.0Topological domainCytoplasmic
TgeneEXD2chr9:21974677chr14:69695533ENST00000409675081_40497.0Topological domainMitochondrial intermembrane
TgeneEXD2chr9:21974677chr14:69695533ENST000004096750826_6210497.0Topological domainCytoplasmic
TgeneEXD2chr9:21974677chr14:69695533ENST000004099492101_40497.0Topological domainMitochondrial intermembrane
TgeneEXD2chr9:21974677chr14:69695533ENST0000040994921026_6210497.0Topological domainCytoplasmic
TgeneEXD2chr9:21974677chr14:69695533ENST00000449989081_40497.0Topological domainMitochondrial intermembrane
TgeneEXD2chr9:21974677chr14:69695533ENST000004499890826_6210497.0Topological domainCytoplasmic
TgeneEXD2chr9:21974677chr14:69695533ENST000004090143115_250497.0TransmembraneHelical
TgeneEXD2chr9:21974677chr14:69695533ENST00000409242195_250497.0TransmembraneHelical
TgeneEXD2chr9:21974677chr14:69695533ENST00000409675085_250497.0TransmembraneHelical
TgeneEXD2chr9:21974677chr14:69695533ENST000004099492105_250497.0TransmembraneHelical
TgeneEXD2chr9:21974677chr14:69695533ENST00000449989085_250497.0TransmembraneHelical

- Not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCDKN2Achr9:21974677chr14:69695533ENST00000304494-13110_13950.0157.0RepeatNote=ANK 4
HgeneCDKN2Achr9:21974677chr14:69695533ENST00000304494-1344_7250.0157.0RepeatNote=ANK 2
HgeneCDKN2Achr9:21974677chr14:69695533ENST00000304494-1377_10650.0157.0RepeatNote=ANK 3
HgeneCDKN2Achr9:21974677chr14:69695533ENST00000446177-13110_13950.0168.0RepeatNote=ANK 4
HgeneCDKN2Achr9:21974677chr14:69695533ENST00000446177-1344_7250.0168.0RepeatNote=ANK 2
HgeneCDKN2Achr9:21974677chr14:69695533ENST00000446177-1377_10650.0168.0RepeatNote=ANK 3
HgeneCDKN2Achr9:21974677chr14:69695533ENST00000494262-14110_1390106.0RepeatNote=ANK 4
HgeneCDKN2Achr9:21974677chr14:69695533ENST00000494262-1411_400106.0RepeatNote=ANK 1
HgeneCDKN2Achr9:21974677chr14:69695533ENST00000494262-1444_720106.0RepeatNote=ANK 2
HgeneCDKN2Achr9:21974677chr14:69695533ENST00000494262-1477_1060106.0RepeatNote=ANK 3
HgeneCDKN2Achr9:21974677chr14:69695533ENST00000498124-14110_13950.0130.66666666666666RepeatNote=ANK 4
HgeneCDKN2Achr9:21974677chr14:69695533ENST00000498124-1444_7250.0130.66666666666666RepeatNote=ANK 2
HgeneCDKN2Achr9:21974677chr14:69695533ENST00000498124-1477_10650.0130.66666666666666RepeatNote=ANK 3
HgeneCDKN2Achr9:21974677chr14:69695533ENST00000498628-13110_1390106.0RepeatNote=ANK 4
HgeneCDKN2Achr9:21974677chr14:69695533ENST00000498628-1311_400106.0RepeatNote=ANK 1
HgeneCDKN2Achr9:21974677chr14:69695533ENST00000498628-1344_720106.0RepeatNote=ANK 2
HgeneCDKN2Achr9:21974677chr14:69695533ENST00000498628-1377_1060106.0RepeatNote=ANK 3
HgeneCDKN2Achr9:21974677chr14:69695533ENST00000578845-12110_1390106.0RepeatNote=ANK 4
HgeneCDKN2Achr9:21974677chr14:69695533ENST00000578845-1211_400106.0RepeatNote=ANK 1
HgeneCDKN2Achr9:21974677chr14:69695533ENST00000578845-1244_720106.0RepeatNote=ANK 2
HgeneCDKN2Achr9:21974677chr14:69695533ENST00000578845-1277_1060106.0RepeatNote=ANK 3
TgeneEXD2chr9:21974677chr14:69695533ENST00000312994191_4111.0622.0Topological domainMitochondrial intermembrane
TgeneEXD2chr9:21974677chr14:69695533ENST000003129941926_621111.0622.0Topological domainCytoplasmic
TgeneEXD2chr9:21974677chr14:69695533ENST00000409018191_4111.0622.0Topological domainMitochondrial intermembrane
TgeneEXD2chr9:21974677chr14:69695533ENST000004090181926_621111.0622.0Topological domainCytoplasmic
TgeneEXD2chr9:21974677chr14:69695533ENST00000312994195_25111.0622.0TransmembraneHelical
TgeneEXD2chr9:21974677chr14:69695533ENST00000409018195_25111.0622.0TransmembraneHelical


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Fusion Protein-Protein Interaction


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type from validated records (BIOGRID-3.4.160)
GenePPI interactors


check button Protein-protein interactors based on sequence similarity (STRING)
GeneSTRING network
CDKN2A
EXD2


check button - Retained interactions in fusion protein (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost interactions due to fusion (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneCDKN2Achr9:21974677chr14:69695533ENST00000361570-131_640220.0CDK5RAP3 and MDM2
HgeneCDKN2Achr9:21974677chr14:69695533ENST00000530628-131_640122.66666666666667CDK5RAP3 and MDM2
HgeneCDKN2Achr9:21974677chr14:69695533ENST00000579755-131_640134.33333333333334CDK5RAP3 and MDM2


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Related Drugs to CDKN2A-EXD2


check button Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDrugSourcePMID

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Related Diseases to CDKN2A-EXD2


check button Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDiseaseSourcePMID

check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource