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Center for Computational Systems Medicine level1
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Fusion Gene Summary

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Fusion Gene Sample Information

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Fusion ORF Analysis

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Fusion Amino Acid Sequences

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Fusion Protein Functional Features

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Fusion Protein-Protein Interaction

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Related drugs with this fusion protein

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Related disease with this fusion protein

Fusion Protein:CERS6-NOSTRIN

Fusion Protein Summary

check button Fusion gene summary
Fusion partner gene informationFusion gene name: CERS6-NOSTRIN
FusionPDB ID: 16003
FusionGDB2.0 ID: 16003
HgeneTgene
Gene symbol

CERS6

NOSTRIN

Gene ID

253782

115677

Gene nameceramide synthase 6nitric oxide synthase trafficking
SynonymsCERS5|LASS6DaIP2
Cytomap

2q24.3

2q24.3

Type of geneprotein-codingprotein-coding
Descriptionceramide synthase 6LAG1 homolog, ceramide synthase 6longevity assurance homolog 6nostrinBM247 homologENOS traffic inducereNOS-trafficking inducerendothelial nitric oxide synthase traffic inducernitric oxide synthase traffic inducernitric oxide synthase traffickerortholog of mouse disabled 2 interacting proein 2
Modification date2020031320200313
UniProtAcc

Q6ZMG9

Q8IVI9

Ensembl transtripts involved in fusion geneENST idsENST00000305747, ENST00000392687, 
ENST00000317647, ENST00000397206, 
ENST00000397209, ENST00000421711, 
ENST00000444448, ENST00000445023, 
ENST00000458381, 
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)* DoF score18 X 12 X 8=17285 X 12 X 5=300
# samples 2210
** MAII scorelog2(22/1728*10)=-2.97352778863881
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(10/300*10)=-1.58496250072116
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context (manual curation of fusion genes in FusionPDB)

PubMed: CERS6 [Title/Abstract] AND NOSTRIN [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)CERS6(169404211)-NOSTRIN(169699501), # samples:2
CERS6(169404211)-NOSTRIN(169707593), # samples:2
Anticipated loss of major functional domain due to fusion event.CERS6-NOSTRIN seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
CERS6-NOSTRIN seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
CERS6-NOSTRIN seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
CERS6-NOSTRIN seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
CERS6-NOSTRIN seems lost the major protein functional domain in Hgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
CERS6-NOSTRIN seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneCERS6

GO:0046513

ceramide biosynthetic process

17609214|17977534


check buttonFusion gene breakpoints across CERS6 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across NOSTRIN (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure


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Fusion Gene Sample Information

check buttonFusion gene information from FusionGDB2.0.
check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4ESCATCGA-L5-A4OWCERS6chr2

169404211

+NOSTRINchr2

169707593

+
ChimerDB4ESCATCGA-L5-A4OWCERS6chr2

169404211

+NOSTRINchr2

169707594

+
ChimerDB4ESCATCGA-V5-A7RBCERS6chr2

169404211

+NOSTRINchr2

169699501

+
ChimerDB4ESCATCGA-V5-A7RBCERS6chr2

169404211

+NOSTRINchr2

169699502

+
ChimerDB4LUSCTCGA-66-2727CERS6chr2

169313128

+NOSTRINchr2

169718470

+
ChimerDB4STADTCGA-D7-6520-01ACERS6chr2

169313128

+NOSTRINchr2

169690737

+
ChimerDB4STADTCGA-D7-6520CERS6chr2

169313128

+NOSTRINchr2

169690736

+


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Fusion ORF Analysis


check buttonFusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000305747CERS6chr2169404211+ENST00000458381NOSTRINchr2169699501+21368632872050587
ENST00000305747CERS6chr2169404211+ENST00000444448NOSTRINchr2169699501+24208632872050587
ENST00000305747CERS6chr2169404211+ENST00000317647NOSTRINchr2169699501+24248632871879530
ENST00000305747CERS6chr2169404211+ENST00000445023NOSTRINchr2169699501+19648632871879530
ENST00000305747CERS6chr2169404211+ENST00000397206NOSTRINchr2169699501+18808632871879531
ENST00000305747CERS6chr2169404211+ENST00000421711NOSTRINchr2169699501+18808632871879531
ENST00000305747CERS6chr2169404211+ENST00000397209NOSTRINchr2169699501+18808632871879531
ENST00000392687CERS6chr2169404211+ENST00000458381NOSTRINchr2169699501+17494761401663507
ENST00000392687CERS6chr2169404211+ENST00000444448NOSTRINchr2169699501+20334761401663507
ENST00000392687CERS6chr2169404211+ENST00000317647NOSTRINchr2169699501+20374761401492450
ENST00000392687CERS6chr2169404211+ENST00000445023NOSTRINchr2169699501+15774761401492450
ENST00000392687CERS6chr2169404211+ENST00000397206NOSTRINchr2169699501+14934761401492451
ENST00000392687CERS6chr2169404211+ENST00000421711NOSTRINchr2169699501+14934761401492451
ENST00000392687CERS6chr2169404211+ENST00000397209NOSTRINchr2169699501+14934761401492451
ENST00000305747CERS6chr2169404211+ENST00000458381NOSTRINchr2169707593+18398632871753488
ENST00000305747CERS6chr2169404211+ENST00000444448NOSTRINchr2169707593+21238632871753488
ENST00000305747CERS6chr2169404211+ENST00000317647NOSTRINchr2169707593+22988632871753488
ENST00000305747CERS6chr2169404211+ENST00000445023NOSTRINchr2169707593+18388632871753488
ENST00000305747CERS6chr2169404211+ENST00000397206NOSTRINchr2169707593+17548632871753489
ENST00000305747CERS6chr2169404211+ENST00000421711NOSTRINchr2169707593+17548632871753489
ENST00000305747CERS6chr2169404211+ENST00000397209NOSTRINchr2169707593+17548632871753489
ENST00000392687CERS6chr2169404211+ENST00000458381NOSTRINchr2169707593+14524761401366408
ENST00000392687CERS6chr2169404211+ENST00000444448NOSTRINchr2169707593+17364761401366408
ENST00000392687CERS6chr2169404211+ENST00000317647NOSTRINchr2169707593+19114761401366408
ENST00000392687CERS6chr2169404211+ENST00000445023NOSTRINchr2169707593+14514761401366408
ENST00000392687CERS6chr2169404211+ENST00000397206NOSTRINchr2169707593+13674761401366409
ENST00000392687CERS6chr2169404211+ENST00000421711NOSTRINchr2169707593+13674761401366409
ENST00000392687CERS6chr2169404211+ENST00000397209NOSTRINchr2169707593+13674761401366409
ENST00000305747CERS6chr2169404211+ENST00000458381NOSTRINchr2169699502+21368632872050587
ENST00000305747CERS6chr2169404211+ENST00000444448NOSTRINchr2169699502+24208632872050587
ENST00000305747CERS6chr2169404211+ENST00000317647NOSTRINchr2169699502+24248632871879530
ENST00000305747CERS6chr2169404211+ENST00000445023NOSTRINchr2169699502+19648632871879530
ENST00000305747CERS6chr2169404211+ENST00000397206NOSTRINchr2169699502+18808632871879531
ENST00000305747CERS6chr2169404211+ENST00000421711NOSTRINchr2169699502+18808632871879531
ENST00000305747CERS6chr2169404211+ENST00000397209NOSTRINchr2169699502+18808632871879531
ENST00000392687CERS6chr2169404211+ENST00000458381NOSTRINchr2169699502+17494761401663507
ENST00000392687CERS6chr2169404211+ENST00000444448NOSTRINchr2169699502+20334761401663507
ENST00000392687CERS6chr2169404211+ENST00000317647NOSTRINchr2169699502+20374761401492450
ENST00000392687CERS6chr2169404211+ENST00000445023NOSTRINchr2169699502+15774761401492450
ENST00000392687CERS6chr2169404211+ENST00000397206NOSTRINchr2169699502+14934761401492451
ENST00000392687CERS6chr2169404211+ENST00000421711NOSTRINchr2169699502+14934761401492451
ENST00000392687CERS6chr2169404211+ENST00000397209NOSTRINchr2169699502+14934761401492451
ENST00000305747CERS6chr2169404211+ENST00000458381NOSTRINchr2169707594+18398632871753488
ENST00000305747CERS6chr2169404211+ENST00000444448NOSTRINchr2169707594+21238632871753488
ENST00000305747CERS6chr2169404211+ENST00000317647NOSTRINchr2169707594+22988632871753488
ENST00000305747CERS6chr2169404211+ENST00000445023NOSTRINchr2169707594+18388632871753488
ENST00000305747CERS6chr2169404211+ENST00000397206NOSTRINchr2169707594+17548632871753489
ENST00000305747CERS6chr2169404211+ENST00000421711NOSTRINchr2169707594+17548632871753489
ENST00000305747CERS6chr2169404211+ENST00000397209NOSTRINchr2169707594+17548632871753489
ENST00000392687CERS6chr2169404211+ENST00000458381NOSTRINchr2169707594+14524761401366408
ENST00000392687CERS6chr2169404211+ENST00000444448NOSTRINchr2169707594+17364761401366408
ENST00000392687CERS6chr2169404211+ENST00000317647NOSTRINchr2169707594+19114761401366408
ENST00000392687CERS6chr2169404211+ENST00000445023NOSTRINchr2169707594+14514761401366408
ENST00000392687CERS6chr2169404211+ENST00000397206NOSTRINchr2169707594+13674761401366409
ENST00000392687CERS6chr2169404211+ENST00000421711NOSTRINchr2169707594+13674761401366409
ENST00000392687CERS6chr2169404211+ENST00000397209NOSTRINchr2169707594+13674761401366409

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000305747ENST00000458381CERS6chr2169404211+NOSTRINchr2169699501+0.0064113770.99358857
ENST00000305747ENST00000444448CERS6chr2169404211+NOSTRINchr2169699501+0.0049403360.9950597
ENST00000305747ENST00000317647CERS6chr2169404211+NOSTRINchr2169699501+0.005737080.9942629
ENST00000305747ENST00000445023CERS6chr2169404211+NOSTRINchr2169699501+0.0082875440.99171245
ENST00000305747ENST00000397206CERS6chr2169404211+NOSTRINchr2169699501+0.0087019940.9912981
ENST00000305747ENST00000421711CERS6chr2169404211+NOSTRINchr2169699501+0.0087019940.9912981
ENST00000305747ENST00000397209CERS6chr2169404211+NOSTRINchr2169699501+0.0087019940.9912981
ENST00000392687ENST00000458381CERS6chr2169404211+NOSTRINchr2169699501+0.0042750250.99572504
ENST00000392687ENST00000444448CERS6chr2169404211+NOSTRINchr2169699501+0.0031186340.99688137
ENST00000392687ENST00000317647CERS6chr2169404211+NOSTRINchr2169699501+0.0036545260.99634546
ENST00000392687ENST00000445023CERS6chr2169404211+NOSTRINchr2169699501+0.0043294850.99567056
ENST00000392687ENST00000397206CERS6chr2169404211+NOSTRINchr2169699501+0.0043444070.99565554
ENST00000392687ENST00000421711CERS6chr2169404211+NOSTRINchr2169699501+0.0043444070.99565554
ENST00000392687ENST00000397209CERS6chr2169404211+NOSTRINchr2169699501+0.0043444070.99565554
ENST00000305747ENST00000458381CERS6chr2169404211+NOSTRINchr2169707593+0.0131771260.98682284
ENST00000305747ENST00000444448CERS6chr2169404211+NOSTRINchr2169707593+0.0091945590.99080545
ENST00000305747ENST00000317647CERS6chr2169404211+NOSTRINchr2169707593+0.0093627660.99063724
ENST00000305747ENST00000445023CERS6chr2169404211+NOSTRINchr2169707593+0.0134727760.98652726
ENST00000305747ENST00000397206CERS6chr2169404211+NOSTRINchr2169707593+0.0142989560.9857011
ENST00000305747ENST00000421711CERS6chr2169404211+NOSTRINchr2169707593+0.0142989560.9857011
ENST00000305747ENST00000397209CERS6chr2169404211+NOSTRINchr2169707593+0.0142989560.9857011
ENST00000392687ENST00000458381CERS6chr2169404211+NOSTRINchr2169707593+0.0072717560.99272823
ENST00000392687ENST00000444448CERS6chr2169404211+NOSTRINchr2169707593+0.0048361380.9951638
ENST00000392687ENST00000317647CERS6chr2169404211+NOSTRINchr2169707593+0.005323530.9946765
ENST00000392687ENST00000445023CERS6chr2169404211+NOSTRINchr2169707593+0.0073536680.99264634
ENST00000392687ENST00000397206CERS6chr2169404211+NOSTRINchr2169707593+0.0073197750.9926803
ENST00000392687ENST00000421711CERS6chr2169404211+NOSTRINchr2169707593+0.0073197750.9926803
ENST00000392687ENST00000397209CERS6chr2169404211+NOSTRINchr2169707593+0.0073197750.9926803
ENST00000305747ENST00000458381CERS6chr2169404211+NOSTRINchr2169699502+0.0064113770.99358857
ENST00000305747ENST00000444448CERS6chr2169404211+NOSTRINchr2169699502+0.0049403360.9950597
ENST00000305747ENST00000317647CERS6chr2169404211+NOSTRINchr2169699502+0.005737080.9942629
ENST00000305747ENST00000445023CERS6chr2169404211+NOSTRINchr2169699502+0.0082875440.99171245
ENST00000305747ENST00000397206CERS6chr2169404211+NOSTRINchr2169699502+0.0087019940.9912981
ENST00000305747ENST00000421711CERS6chr2169404211+NOSTRINchr2169699502+0.0087019940.9912981
ENST00000305747ENST00000397209CERS6chr2169404211+NOSTRINchr2169699502+0.0087019940.9912981
ENST00000392687ENST00000458381CERS6chr2169404211+NOSTRINchr2169699502+0.0042750250.99572504
ENST00000392687ENST00000444448CERS6chr2169404211+NOSTRINchr2169699502+0.0031186340.99688137
ENST00000392687ENST00000317647CERS6chr2169404211+NOSTRINchr2169699502+0.0036545260.99634546
ENST00000392687ENST00000445023CERS6chr2169404211+NOSTRINchr2169699502+0.0043294850.99567056
ENST00000392687ENST00000397206CERS6chr2169404211+NOSTRINchr2169699502+0.0043444070.99565554
ENST00000392687ENST00000421711CERS6chr2169404211+NOSTRINchr2169699502+0.0043444070.99565554
ENST00000392687ENST00000397209CERS6chr2169404211+NOSTRINchr2169699502+0.0043444070.99565554
ENST00000305747ENST00000458381CERS6chr2169404211+NOSTRINchr2169707594+0.0131771260.98682284
ENST00000305747ENST00000444448CERS6chr2169404211+NOSTRINchr2169707594+0.0091945590.99080545
ENST00000305747ENST00000317647CERS6chr2169404211+NOSTRINchr2169707594+0.0093627660.99063724
ENST00000305747ENST00000445023CERS6chr2169404211+NOSTRINchr2169707594+0.0134727760.98652726
ENST00000305747ENST00000397206CERS6chr2169404211+NOSTRINchr2169707594+0.0142989560.9857011
ENST00000305747ENST00000421711CERS6chr2169404211+NOSTRINchr2169707594+0.0142989560.9857011
ENST00000305747ENST00000397209CERS6chr2169404211+NOSTRINchr2169707594+0.0142989560.9857011
ENST00000392687ENST00000458381CERS6chr2169404211+NOSTRINchr2169707594+0.0072717560.99272823
ENST00000392687ENST00000444448CERS6chr2169404211+NOSTRINchr2169707594+0.0048361380.9951638
ENST00000392687ENST00000317647CERS6chr2169404211+NOSTRINchr2169707594+0.005323530.9946765
ENST00000392687ENST00000445023CERS6chr2169404211+NOSTRINchr2169707594+0.0073536680.99264634
ENST00000392687ENST00000397206CERS6chr2169404211+NOSTRINchr2169707594+0.0073197750.9926803
ENST00000392687ENST00000421711CERS6chr2169404211+NOSTRINchr2169707594+0.0073197750.9926803
ENST00000392687ENST00000397209CERS6chr2169404211+NOSTRINchr2169707594+0.0073197750.9926803

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Fusion Amino Acid Sequences


check button For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

>16003_16003_1_CERS6-NOSTRIN_CERS6_chr2_169404211_ENST00000305747_NOSTRIN_chr2_169699501_ENST00000317647_length(amino acids)=530AA_BP=1
MAACVPRCLTRRRANQGGRPELPCDGQGGPFPQRGQREERTGARREPSRAAAAEEAAAAGGSSGGGGTGSGPAGRASPGALRGGELGGLR
VPQDRSGQSKMAGILAWFWNERFWLPHNVTWADLKNTEEATFPQAEDLYLAFPLAFCIFMVRLIFERFVAKPCAIALNIQANGPQIAPPN
AILEKVFTAITKLLNKLTKSTEKLEKEDENYYQKNMAGYSTRLKWENTLENCYQSILELEKERIQLLCNNLNQYSQHISLFGQTLTTCHT
QIHCAISKIDIEKDIQAVMEETAILSTENKSEFLLTDYFEEDPNSAMDKERRKSLLKPKLLRLQRDIEKASKDKEGLERMLKTYSSTSSF
SDAKSQKDTAALMDENNLKLDLLEANSYKLSSMLAELEQRPQPSHPCSNSIFRWREKEHTHSYVKISRPFLMKRLENIVSKASSGGQSNP

--------------------------------------------------------------

>16003_16003_2_CERS6-NOSTRIN_CERS6_chr2_169404211_ENST00000305747_NOSTRIN_chr2_169699501_ENST00000397206_length(amino acids)=531AA_BP=1
MAACVPRCLTRRRANQGGRPELPCDGQGGPFPQRGQREERTGARREPSRAAAAEEAAAAGGSSGGGGTGSGPAGRASPGALRGGELGGLR
VPQDRSGQSKMAGILAWFWNERFWLPHNVTWADLKNTEEATFPQAEDLYLAFPLAFCIFMVRLIFERFVAKPCAIALNIQANGPQIAPPN
AILEKVFTAITKLLNKLTKSTEKLEKEDENYYQKNMAGYSTRLKWENTLENCYQSILELEKERIQLLCNNLNQYSQHISLFGQTLTTCHT
QIHCAISKIDIEKDIQAVMEETAILSTENKSEFLLTDYFEEDPNSAMDKERRKSLLKPKLLRLQRDIEKASKDKEGLERMLKTYSSTSSF
SDAKSQKDTAALMDENNLKLDLLEANSYKLSSMLAELEQRPQPSHPCSNSIFRWREKEHTHSYVKISRPFLMKRLENIVSKASSGGQSNP

--------------------------------------------------------------

>16003_16003_3_CERS6-NOSTRIN_CERS6_chr2_169404211_ENST00000305747_NOSTRIN_chr2_169699501_ENST00000397209_length(amino acids)=531AA_BP=1
MAACVPRCLTRRRANQGGRPELPCDGQGGPFPQRGQREERTGARREPSRAAAAEEAAAAGGSSGGGGTGSGPAGRASPGALRGGELGGLR
VPQDRSGQSKMAGILAWFWNERFWLPHNVTWADLKNTEEATFPQAEDLYLAFPLAFCIFMVRLIFERFVAKPCAIALNIQANGPQIAPPN
AILEKVFTAITKLLNKLTKSTEKLEKEDENYYQKNMAGYSTRLKWENTLENCYQSILELEKERIQLLCNNLNQYSQHISLFGQTLTTCHT
QIHCAISKIDIEKDIQAVMEETAILSTENKSEFLLTDYFEEDPNSAMDKERRKSLLKPKLLRLQRDIEKASKDKEGLERMLKTYSSTSSF
SDAKSQKDTAALMDENNLKLDLLEANSYKLSSMLAELEQRPQPSHPCSNSIFRWREKEHTHSYVKISRPFLMKRLENIVSKASSGGQSNP

--------------------------------------------------------------

>16003_16003_4_CERS6-NOSTRIN_CERS6_chr2_169404211_ENST00000305747_NOSTRIN_chr2_169699501_ENST00000421711_length(amino acids)=531AA_BP=1
MAACVPRCLTRRRANQGGRPELPCDGQGGPFPQRGQREERTGARREPSRAAAAEEAAAAGGSSGGGGTGSGPAGRASPGALRGGELGGLR
VPQDRSGQSKMAGILAWFWNERFWLPHNVTWADLKNTEEATFPQAEDLYLAFPLAFCIFMVRLIFERFVAKPCAIALNIQANGPQIAPPN
AILEKVFTAITKLLNKLTKSTEKLEKEDENYYQKNMAGYSTRLKWENTLENCYQSILELEKERIQLLCNNLNQYSQHISLFGQTLTTCHT
QIHCAISKIDIEKDIQAVMEETAILSTENKSEFLLTDYFEEDPNSAMDKERRKSLLKPKLLRLQRDIEKASKDKEGLERMLKTYSSTSSF
SDAKSQKDTAALMDENNLKLDLLEANSYKLSSMLAELEQRPQPSHPCSNSIFRWREKEHTHSYVKISRPFLMKRLENIVSKASSGGQSNP

--------------------------------------------------------------

>16003_16003_5_CERS6-NOSTRIN_CERS6_chr2_169404211_ENST00000305747_NOSTRIN_chr2_169699501_ENST00000444448_length(amino acids)=587AA_BP=1
MAACVPRCLTRRRANQGGRPELPCDGQGGPFPQRGQREERTGARREPSRAAAAEEAAAAGGSSGGGGTGSGPAGRASPGALRGGELGGLR
VPQDRSGQSKMAGILAWFWNERFWLPHNVTWADLKNTEEATFPQAEDLYLAFPLAFCIFMVRLIFERFVAKPCAIALNIQANGPQIAPPN
AILEKVFTAITKLLNKLTKSTEKLEKEDENYYQKNMAGYSTRLKWENTLENCYQVTHSICLYAFWVKRAWGKCVSDLRYQDTFLPGNLPP
LWFGYDIVKRLIMRLCSVCLQSILELEKERIQLLCNNLNQYSQHISLFGQTLTTCHTQIHCAISKIDIEKDIQAVMEETAILSTENKSEF
LLTDYFEEDPNSAMDKERRKSLLKPKLLRLQRDIEKASKDKEGLERMLKTYSSTSSFSDAKSQKDTAALMDENNLKLDLLEANSYKLSSM
LAELEQRPQPSHPCSNSIFRWREKEHTHSYVKISRPFLMKRLENIVSKASSGGQSNPGSSTPAPGAAQLSSRLCKALYSFQARQDDELNL

--------------------------------------------------------------

>16003_16003_6_CERS6-NOSTRIN_CERS6_chr2_169404211_ENST00000305747_NOSTRIN_chr2_169699501_ENST00000445023_length(amino acids)=530AA_BP=1
MAACVPRCLTRRRANQGGRPELPCDGQGGPFPQRGQREERTGARREPSRAAAAEEAAAAGGSSGGGGTGSGPAGRASPGALRGGELGGLR
VPQDRSGQSKMAGILAWFWNERFWLPHNVTWADLKNTEEATFPQAEDLYLAFPLAFCIFMVRLIFERFVAKPCAIALNIQANGPQIAPPN
AILEKVFTAITKLLNKLTKSTEKLEKEDENYYQKNMAGYSTRLKWENTLENCYQSILELEKERIQLLCNNLNQYSQHISLFGQTLTTCHT
QIHCAISKIDIEKDIQAVMEETAILSTENKSEFLLTDYFEEDPNSAMDKERRKSLLKPKLLRLQRDIEKASKDKEGLERMLKTYSSTSSF
SDAKSQKDTAALMDENNLKLDLLEANSYKLSSMLAELEQRPQPSHPCSNSIFRWREKEHTHSYVKISRPFLMKRLENIVSKASSGGQSNP

--------------------------------------------------------------

>16003_16003_7_CERS6-NOSTRIN_CERS6_chr2_169404211_ENST00000305747_NOSTRIN_chr2_169699501_ENST00000458381_length(amino acids)=587AA_BP=1
MAACVPRCLTRRRANQGGRPELPCDGQGGPFPQRGQREERTGARREPSRAAAAEEAAAAGGSSGGGGTGSGPAGRASPGALRGGELGGLR
VPQDRSGQSKMAGILAWFWNERFWLPHNVTWADLKNTEEATFPQAEDLYLAFPLAFCIFMVRLIFERFVAKPCAIALNIQANGPQIAPPN
AILEKVFTAITKLLNKLTKSTEKLEKEDENYYQKNMAGYSTRLKWENTLENCYQVTHSICLYAFWVKRAWGKCVSDLRYQDTFLPGNLPP
LWFGYDIVKRLIMRLCSVCLQSILELEKERIQLLCNNLNQYSQHISLFGQTLTTCHTQIHCAISKIDIEKDIQAVMEETAILSTENKSEF
LLTDYFEEDPNSAMDKERRKSLLKPKLLRLQRDIEKASKDKEGLERMLKTYSSTSSFSDAKSQKDTAALMDENNLKLDLLEANSYKLSSM
LAELEQRPQPSHPCSNSIFRWREKEHTHSYVKISRPFLMKRLENIVSKASSGGQSNPGSSTPAPGAAQLSSRLCKALYSFQARQDDELNL

--------------------------------------------------------------

>16003_16003_8_CERS6-NOSTRIN_CERS6_chr2_169404211_ENST00000305747_NOSTRIN_chr2_169699502_ENST00000317647_length(amino acids)=530AA_BP=1
MAACVPRCLTRRRANQGGRPELPCDGQGGPFPQRGQREERTGARREPSRAAAAEEAAAAGGSSGGGGTGSGPAGRASPGALRGGELGGLR
VPQDRSGQSKMAGILAWFWNERFWLPHNVTWADLKNTEEATFPQAEDLYLAFPLAFCIFMVRLIFERFVAKPCAIALNIQANGPQIAPPN
AILEKVFTAITKLLNKLTKSTEKLEKEDENYYQKNMAGYSTRLKWENTLENCYQSILELEKERIQLLCNNLNQYSQHISLFGQTLTTCHT
QIHCAISKIDIEKDIQAVMEETAILSTENKSEFLLTDYFEEDPNSAMDKERRKSLLKPKLLRLQRDIEKASKDKEGLERMLKTYSSTSSF
SDAKSQKDTAALMDENNLKLDLLEANSYKLSSMLAELEQRPQPSHPCSNSIFRWREKEHTHSYVKISRPFLMKRLENIVSKASSGGQSNP

--------------------------------------------------------------

>16003_16003_9_CERS6-NOSTRIN_CERS6_chr2_169404211_ENST00000305747_NOSTRIN_chr2_169699502_ENST00000397206_length(amino acids)=531AA_BP=1
MAACVPRCLTRRRANQGGRPELPCDGQGGPFPQRGQREERTGARREPSRAAAAEEAAAAGGSSGGGGTGSGPAGRASPGALRGGELGGLR
VPQDRSGQSKMAGILAWFWNERFWLPHNVTWADLKNTEEATFPQAEDLYLAFPLAFCIFMVRLIFERFVAKPCAIALNIQANGPQIAPPN
AILEKVFTAITKLLNKLTKSTEKLEKEDENYYQKNMAGYSTRLKWENTLENCYQSILELEKERIQLLCNNLNQYSQHISLFGQTLTTCHT
QIHCAISKIDIEKDIQAVMEETAILSTENKSEFLLTDYFEEDPNSAMDKERRKSLLKPKLLRLQRDIEKASKDKEGLERMLKTYSSTSSF
SDAKSQKDTAALMDENNLKLDLLEANSYKLSSMLAELEQRPQPSHPCSNSIFRWREKEHTHSYVKISRPFLMKRLENIVSKASSGGQSNP

--------------------------------------------------------------

>16003_16003_10_CERS6-NOSTRIN_CERS6_chr2_169404211_ENST00000305747_NOSTRIN_chr2_169699502_ENST00000397209_length(amino acids)=531AA_BP=1
MAACVPRCLTRRRANQGGRPELPCDGQGGPFPQRGQREERTGARREPSRAAAAEEAAAAGGSSGGGGTGSGPAGRASPGALRGGELGGLR
VPQDRSGQSKMAGILAWFWNERFWLPHNVTWADLKNTEEATFPQAEDLYLAFPLAFCIFMVRLIFERFVAKPCAIALNIQANGPQIAPPN
AILEKVFTAITKLLNKLTKSTEKLEKEDENYYQKNMAGYSTRLKWENTLENCYQSILELEKERIQLLCNNLNQYSQHISLFGQTLTTCHT
QIHCAISKIDIEKDIQAVMEETAILSTENKSEFLLTDYFEEDPNSAMDKERRKSLLKPKLLRLQRDIEKASKDKEGLERMLKTYSSTSSF
SDAKSQKDTAALMDENNLKLDLLEANSYKLSSMLAELEQRPQPSHPCSNSIFRWREKEHTHSYVKISRPFLMKRLENIVSKASSGGQSNP

--------------------------------------------------------------

>16003_16003_11_CERS6-NOSTRIN_CERS6_chr2_169404211_ENST00000305747_NOSTRIN_chr2_169699502_ENST00000421711_length(amino acids)=531AA_BP=1
MAACVPRCLTRRRANQGGRPELPCDGQGGPFPQRGQREERTGARREPSRAAAAEEAAAAGGSSGGGGTGSGPAGRASPGALRGGELGGLR
VPQDRSGQSKMAGILAWFWNERFWLPHNVTWADLKNTEEATFPQAEDLYLAFPLAFCIFMVRLIFERFVAKPCAIALNIQANGPQIAPPN
AILEKVFTAITKLLNKLTKSTEKLEKEDENYYQKNMAGYSTRLKWENTLENCYQSILELEKERIQLLCNNLNQYSQHISLFGQTLTTCHT
QIHCAISKIDIEKDIQAVMEETAILSTENKSEFLLTDYFEEDPNSAMDKERRKSLLKPKLLRLQRDIEKASKDKEGLERMLKTYSSTSSF
SDAKSQKDTAALMDENNLKLDLLEANSYKLSSMLAELEQRPQPSHPCSNSIFRWREKEHTHSYVKISRPFLMKRLENIVSKASSGGQSNP

--------------------------------------------------------------

>16003_16003_12_CERS6-NOSTRIN_CERS6_chr2_169404211_ENST00000305747_NOSTRIN_chr2_169699502_ENST00000444448_length(amino acids)=587AA_BP=1
MAACVPRCLTRRRANQGGRPELPCDGQGGPFPQRGQREERTGARREPSRAAAAEEAAAAGGSSGGGGTGSGPAGRASPGALRGGELGGLR
VPQDRSGQSKMAGILAWFWNERFWLPHNVTWADLKNTEEATFPQAEDLYLAFPLAFCIFMVRLIFERFVAKPCAIALNIQANGPQIAPPN
AILEKVFTAITKLLNKLTKSTEKLEKEDENYYQKNMAGYSTRLKWENTLENCYQVTHSICLYAFWVKRAWGKCVSDLRYQDTFLPGNLPP
LWFGYDIVKRLIMRLCSVCLQSILELEKERIQLLCNNLNQYSQHISLFGQTLTTCHTQIHCAISKIDIEKDIQAVMEETAILSTENKSEF
LLTDYFEEDPNSAMDKERRKSLLKPKLLRLQRDIEKASKDKEGLERMLKTYSSTSSFSDAKSQKDTAALMDENNLKLDLLEANSYKLSSM
LAELEQRPQPSHPCSNSIFRWREKEHTHSYVKISRPFLMKRLENIVSKASSGGQSNPGSSTPAPGAAQLSSRLCKALYSFQARQDDELNL

--------------------------------------------------------------

>16003_16003_13_CERS6-NOSTRIN_CERS6_chr2_169404211_ENST00000305747_NOSTRIN_chr2_169699502_ENST00000445023_length(amino acids)=530AA_BP=1
MAACVPRCLTRRRANQGGRPELPCDGQGGPFPQRGQREERTGARREPSRAAAAEEAAAAGGSSGGGGTGSGPAGRASPGALRGGELGGLR
VPQDRSGQSKMAGILAWFWNERFWLPHNVTWADLKNTEEATFPQAEDLYLAFPLAFCIFMVRLIFERFVAKPCAIALNIQANGPQIAPPN
AILEKVFTAITKLLNKLTKSTEKLEKEDENYYQKNMAGYSTRLKWENTLENCYQSILELEKERIQLLCNNLNQYSQHISLFGQTLTTCHT
QIHCAISKIDIEKDIQAVMEETAILSTENKSEFLLTDYFEEDPNSAMDKERRKSLLKPKLLRLQRDIEKASKDKEGLERMLKTYSSTSSF
SDAKSQKDTAALMDENNLKLDLLEANSYKLSSMLAELEQRPQPSHPCSNSIFRWREKEHTHSYVKISRPFLMKRLENIVSKASSGGQSNP

--------------------------------------------------------------

>16003_16003_14_CERS6-NOSTRIN_CERS6_chr2_169404211_ENST00000305747_NOSTRIN_chr2_169699502_ENST00000458381_length(amino acids)=587AA_BP=1
MAACVPRCLTRRRANQGGRPELPCDGQGGPFPQRGQREERTGARREPSRAAAAEEAAAAGGSSGGGGTGSGPAGRASPGALRGGELGGLR
VPQDRSGQSKMAGILAWFWNERFWLPHNVTWADLKNTEEATFPQAEDLYLAFPLAFCIFMVRLIFERFVAKPCAIALNIQANGPQIAPPN
AILEKVFTAITKLLNKLTKSTEKLEKEDENYYQKNMAGYSTRLKWENTLENCYQVTHSICLYAFWVKRAWGKCVSDLRYQDTFLPGNLPP
LWFGYDIVKRLIMRLCSVCLQSILELEKERIQLLCNNLNQYSQHISLFGQTLTTCHTQIHCAISKIDIEKDIQAVMEETAILSTENKSEF
LLTDYFEEDPNSAMDKERRKSLLKPKLLRLQRDIEKASKDKEGLERMLKTYSSTSSFSDAKSQKDTAALMDENNLKLDLLEANSYKLSSM
LAELEQRPQPSHPCSNSIFRWREKEHTHSYVKISRPFLMKRLENIVSKASSGGQSNPGSSTPAPGAAQLSSRLCKALYSFQARQDDELNL

--------------------------------------------------------------

>16003_16003_15_CERS6-NOSTRIN_CERS6_chr2_169404211_ENST00000305747_NOSTRIN_chr2_169707593_ENST00000317647_length(amino acids)=488AA_BP=1
MAACVPRCLTRRRANQGGRPELPCDGQGGPFPQRGQREERTGARREPSRAAAAEEAAAAGGSSGGGGTGSGPAGRASPGALRGGELGGLR
VPQDRSGQSKMAGILAWFWNERFWLPHNVTWADLKNTEEATFPQAEDLYLAFPLAFCIFMVRLIFERFVAKPCAIALNIQANGPQIAPPN
AILEKVFTAITKSILELEKERIQLLCNNLNQYSQHISLFGQTLTTCHTQIHCAISKIDIEKDIQAVMEETAILSTENKSEFLLTDYFEED
PNSAMDKERRKSLLKPKLLRLQRDIEKASKDKEGLERMLKTYSSTSSFSDAKSQKDTAALMDENNLKLDLLEANSYKLSSMLAELEQRPQ
PSHPCSNSIFRWREKEHTHSYVKISRPFLMKRLENIVSKASSGGQSNPGSSTPAPGAAQLSSRLCKALYSFQARQDDELNLEKGDIVIIH

--------------------------------------------------------------

>16003_16003_16_CERS6-NOSTRIN_CERS6_chr2_169404211_ENST00000305747_NOSTRIN_chr2_169707593_ENST00000397206_length(amino acids)=489AA_BP=1
MAACVPRCLTRRRANQGGRPELPCDGQGGPFPQRGQREERTGARREPSRAAAAEEAAAAGGSSGGGGTGSGPAGRASPGALRGGELGGLR
VPQDRSGQSKMAGILAWFWNERFWLPHNVTWADLKNTEEATFPQAEDLYLAFPLAFCIFMVRLIFERFVAKPCAIALNIQANGPQIAPPN
AILEKVFTAITKSILELEKERIQLLCNNLNQYSQHISLFGQTLTTCHTQIHCAISKIDIEKDIQAVMEETAILSTENKSEFLLTDYFEED
PNSAMDKERRKSLLKPKLLRLQRDIEKASKDKEGLERMLKTYSSTSSFSDAKSQKDTAALMDENNLKLDLLEANSYKLSSMLAELEQRPQ
PSHPCSNSIFRWREKEHTHSYVKISRPFLMKRLENIVSKASSGGQSNPGSSTPAPGAAQLSSRLCKALYSFQARQDDELNLEKGDIVIIH

--------------------------------------------------------------

>16003_16003_17_CERS6-NOSTRIN_CERS6_chr2_169404211_ENST00000305747_NOSTRIN_chr2_169707593_ENST00000397209_length(amino acids)=489AA_BP=1
MAACVPRCLTRRRANQGGRPELPCDGQGGPFPQRGQREERTGARREPSRAAAAEEAAAAGGSSGGGGTGSGPAGRASPGALRGGELGGLR
VPQDRSGQSKMAGILAWFWNERFWLPHNVTWADLKNTEEATFPQAEDLYLAFPLAFCIFMVRLIFERFVAKPCAIALNIQANGPQIAPPN
AILEKVFTAITKSILELEKERIQLLCNNLNQYSQHISLFGQTLTTCHTQIHCAISKIDIEKDIQAVMEETAILSTENKSEFLLTDYFEED
PNSAMDKERRKSLLKPKLLRLQRDIEKASKDKEGLERMLKTYSSTSSFSDAKSQKDTAALMDENNLKLDLLEANSYKLSSMLAELEQRPQ
PSHPCSNSIFRWREKEHTHSYVKISRPFLMKRLENIVSKASSGGQSNPGSSTPAPGAAQLSSRLCKALYSFQARQDDELNLEKGDIVIIH

--------------------------------------------------------------

>16003_16003_18_CERS6-NOSTRIN_CERS6_chr2_169404211_ENST00000305747_NOSTRIN_chr2_169707593_ENST00000421711_length(amino acids)=489AA_BP=1
MAACVPRCLTRRRANQGGRPELPCDGQGGPFPQRGQREERTGARREPSRAAAAEEAAAAGGSSGGGGTGSGPAGRASPGALRGGELGGLR
VPQDRSGQSKMAGILAWFWNERFWLPHNVTWADLKNTEEATFPQAEDLYLAFPLAFCIFMVRLIFERFVAKPCAIALNIQANGPQIAPPN
AILEKVFTAITKSILELEKERIQLLCNNLNQYSQHISLFGQTLTTCHTQIHCAISKIDIEKDIQAVMEETAILSTENKSEFLLTDYFEED
PNSAMDKERRKSLLKPKLLRLQRDIEKASKDKEGLERMLKTYSSTSSFSDAKSQKDTAALMDENNLKLDLLEANSYKLSSMLAELEQRPQ
PSHPCSNSIFRWREKEHTHSYVKISRPFLMKRLENIVSKASSGGQSNPGSSTPAPGAAQLSSRLCKALYSFQARQDDELNLEKGDIVIIH

--------------------------------------------------------------

>16003_16003_19_CERS6-NOSTRIN_CERS6_chr2_169404211_ENST00000305747_NOSTRIN_chr2_169707593_ENST00000444448_length(amino acids)=488AA_BP=1
MAACVPRCLTRRRANQGGRPELPCDGQGGPFPQRGQREERTGARREPSRAAAAEEAAAAGGSSGGGGTGSGPAGRASPGALRGGELGGLR
VPQDRSGQSKMAGILAWFWNERFWLPHNVTWADLKNTEEATFPQAEDLYLAFPLAFCIFMVRLIFERFVAKPCAIALNIQANGPQIAPPN
AILEKVFTAITKSILELEKERIQLLCNNLNQYSQHISLFGQTLTTCHTQIHCAISKIDIEKDIQAVMEETAILSTENKSEFLLTDYFEED
PNSAMDKERRKSLLKPKLLRLQRDIEKASKDKEGLERMLKTYSSTSSFSDAKSQKDTAALMDENNLKLDLLEANSYKLSSMLAELEQRPQ
PSHPCSNSIFRWREKEHTHSYVKISRPFLMKRLENIVSKASSGGQSNPGSSTPAPGAAQLSSRLCKALYSFQARQDDELNLEKGDIVIIH

--------------------------------------------------------------

>16003_16003_20_CERS6-NOSTRIN_CERS6_chr2_169404211_ENST00000305747_NOSTRIN_chr2_169707593_ENST00000445023_length(amino acids)=488AA_BP=1
MAACVPRCLTRRRANQGGRPELPCDGQGGPFPQRGQREERTGARREPSRAAAAEEAAAAGGSSGGGGTGSGPAGRASPGALRGGELGGLR
VPQDRSGQSKMAGILAWFWNERFWLPHNVTWADLKNTEEATFPQAEDLYLAFPLAFCIFMVRLIFERFVAKPCAIALNIQANGPQIAPPN
AILEKVFTAITKSILELEKERIQLLCNNLNQYSQHISLFGQTLTTCHTQIHCAISKIDIEKDIQAVMEETAILSTENKSEFLLTDYFEED
PNSAMDKERRKSLLKPKLLRLQRDIEKASKDKEGLERMLKTYSSTSSFSDAKSQKDTAALMDENNLKLDLLEANSYKLSSMLAELEQRPQ
PSHPCSNSIFRWREKEHTHSYVKISRPFLMKRLENIVSKASSGGQSNPGSSTPAPGAAQLSSRLCKALYSFQARQDDELNLEKGDIVIIH

--------------------------------------------------------------

>16003_16003_21_CERS6-NOSTRIN_CERS6_chr2_169404211_ENST00000305747_NOSTRIN_chr2_169707593_ENST00000458381_length(amino acids)=488AA_BP=1
MAACVPRCLTRRRANQGGRPELPCDGQGGPFPQRGQREERTGARREPSRAAAAEEAAAAGGSSGGGGTGSGPAGRASPGALRGGELGGLR
VPQDRSGQSKMAGILAWFWNERFWLPHNVTWADLKNTEEATFPQAEDLYLAFPLAFCIFMVRLIFERFVAKPCAIALNIQANGPQIAPPN
AILEKVFTAITKSILELEKERIQLLCNNLNQYSQHISLFGQTLTTCHTQIHCAISKIDIEKDIQAVMEETAILSTENKSEFLLTDYFEED
PNSAMDKERRKSLLKPKLLRLQRDIEKASKDKEGLERMLKTYSSTSSFSDAKSQKDTAALMDENNLKLDLLEANSYKLSSMLAELEQRPQ
PSHPCSNSIFRWREKEHTHSYVKISRPFLMKRLENIVSKASSGGQSNPGSSTPAPGAAQLSSRLCKALYSFQARQDDELNLEKGDIVIIH

--------------------------------------------------------------

>16003_16003_22_CERS6-NOSTRIN_CERS6_chr2_169404211_ENST00000305747_NOSTRIN_chr2_169707594_ENST00000317647_length(amino acids)=488AA_BP=1
MAACVPRCLTRRRANQGGRPELPCDGQGGPFPQRGQREERTGARREPSRAAAAEEAAAAGGSSGGGGTGSGPAGRASPGALRGGELGGLR
VPQDRSGQSKMAGILAWFWNERFWLPHNVTWADLKNTEEATFPQAEDLYLAFPLAFCIFMVRLIFERFVAKPCAIALNIQANGPQIAPPN
AILEKVFTAITKSILELEKERIQLLCNNLNQYSQHISLFGQTLTTCHTQIHCAISKIDIEKDIQAVMEETAILSTENKSEFLLTDYFEED
PNSAMDKERRKSLLKPKLLRLQRDIEKASKDKEGLERMLKTYSSTSSFSDAKSQKDTAALMDENNLKLDLLEANSYKLSSMLAELEQRPQ
PSHPCSNSIFRWREKEHTHSYVKISRPFLMKRLENIVSKASSGGQSNPGSSTPAPGAAQLSSRLCKALYSFQARQDDELNLEKGDIVIIH

--------------------------------------------------------------

>16003_16003_23_CERS6-NOSTRIN_CERS6_chr2_169404211_ENST00000305747_NOSTRIN_chr2_169707594_ENST00000397206_length(amino acids)=489AA_BP=1
MAACVPRCLTRRRANQGGRPELPCDGQGGPFPQRGQREERTGARREPSRAAAAEEAAAAGGSSGGGGTGSGPAGRASPGALRGGELGGLR
VPQDRSGQSKMAGILAWFWNERFWLPHNVTWADLKNTEEATFPQAEDLYLAFPLAFCIFMVRLIFERFVAKPCAIALNIQANGPQIAPPN
AILEKVFTAITKSILELEKERIQLLCNNLNQYSQHISLFGQTLTTCHTQIHCAISKIDIEKDIQAVMEETAILSTENKSEFLLTDYFEED
PNSAMDKERRKSLLKPKLLRLQRDIEKASKDKEGLERMLKTYSSTSSFSDAKSQKDTAALMDENNLKLDLLEANSYKLSSMLAELEQRPQ
PSHPCSNSIFRWREKEHTHSYVKISRPFLMKRLENIVSKASSGGQSNPGSSTPAPGAAQLSSRLCKALYSFQARQDDELNLEKGDIVIIH

--------------------------------------------------------------

>16003_16003_24_CERS6-NOSTRIN_CERS6_chr2_169404211_ENST00000305747_NOSTRIN_chr2_169707594_ENST00000397209_length(amino acids)=489AA_BP=1
MAACVPRCLTRRRANQGGRPELPCDGQGGPFPQRGQREERTGARREPSRAAAAEEAAAAGGSSGGGGTGSGPAGRASPGALRGGELGGLR
VPQDRSGQSKMAGILAWFWNERFWLPHNVTWADLKNTEEATFPQAEDLYLAFPLAFCIFMVRLIFERFVAKPCAIALNIQANGPQIAPPN
AILEKVFTAITKSILELEKERIQLLCNNLNQYSQHISLFGQTLTTCHTQIHCAISKIDIEKDIQAVMEETAILSTENKSEFLLTDYFEED
PNSAMDKERRKSLLKPKLLRLQRDIEKASKDKEGLERMLKTYSSTSSFSDAKSQKDTAALMDENNLKLDLLEANSYKLSSMLAELEQRPQ
PSHPCSNSIFRWREKEHTHSYVKISRPFLMKRLENIVSKASSGGQSNPGSSTPAPGAAQLSSRLCKALYSFQARQDDELNLEKGDIVIIH

--------------------------------------------------------------

>16003_16003_25_CERS6-NOSTRIN_CERS6_chr2_169404211_ENST00000305747_NOSTRIN_chr2_169707594_ENST00000421711_length(amino acids)=489AA_BP=1
MAACVPRCLTRRRANQGGRPELPCDGQGGPFPQRGQREERTGARREPSRAAAAEEAAAAGGSSGGGGTGSGPAGRASPGALRGGELGGLR
VPQDRSGQSKMAGILAWFWNERFWLPHNVTWADLKNTEEATFPQAEDLYLAFPLAFCIFMVRLIFERFVAKPCAIALNIQANGPQIAPPN
AILEKVFTAITKSILELEKERIQLLCNNLNQYSQHISLFGQTLTTCHTQIHCAISKIDIEKDIQAVMEETAILSTENKSEFLLTDYFEED
PNSAMDKERRKSLLKPKLLRLQRDIEKASKDKEGLERMLKTYSSTSSFSDAKSQKDTAALMDENNLKLDLLEANSYKLSSMLAELEQRPQ
PSHPCSNSIFRWREKEHTHSYVKISRPFLMKRLENIVSKASSGGQSNPGSSTPAPGAAQLSSRLCKALYSFQARQDDELNLEKGDIVIIH

--------------------------------------------------------------

>16003_16003_26_CERS6-NOSTRIN_CERS6_chr2_169404211_ENST00000305747_NOSTRIN_chr2_169707594_ENST00000444448_length(amino acids)=488AA_BP=1
MAACVPRCLTRRRANQGGRPELPCDGQGGPFPQRGQREERTGARREPSRAAAAEEAAAAGGSSGGGGTGSGPAGRASPGALRGGELGGLR
VPQDRSGQSKMAGILAWFWNERFWLPHNVTWADLKNTEEATFPQAEDLYLAFPLAFCIFMVRLIFERFVAKPCAIALNIQANGPQIAPPN
AILEKVFTAITKSILELEKERIQLLCNNLNQYSQHISLFGQTLTTCHTQIHCAISKIDIEKDIQAVMEETAILSTENKSEFLLTDYFEED
PNSAMDKERRKSLLKPKLLRLQRDIEKASKDKEGLERMLKTYSSTSSFSDAKSQKDTAALMDENNLKLDLLEANSYKLSSMLAELEQRPQ
PSHPCSNSIFRWREKEHTHSYVKISRPFLMKRLENIVSKASSGGQSNPGSSTPAPGAAQLSSRLCKALYSFQARQDDELNLEKGDIVIIH

--------------------------------------------------------------

>16003_16003_27_CERS6-NOSTRIN_CERS6_chr2_169404211_ENST00000305747_NOSTRIN_chr2_169707594_ENST00000445023_length(amino acids)=488AA_BP=1
MAACVPRCLTRRRANQGGRPELPCDGQGGPFPQRGQREERTGARREPSRAAAAEEAAAAGGSSGGGGTGSGPAGRASPGALRGGELGGLR
VPQDRSGQSKMAGILAWFWNERFWLPHNVTWADLKNTEEATFPQAEDLYLAFPLAFCIFMVRLIFERFVAKPCAIALNIQANGPQIAPPN
AILEKVFTAITKSILELEKERIQLLCNNLNQYSQHISLFGQTLTTCHTQIHCAISKIDIEKDIQAVMEETAILSTENKSEFLLTDYFEED
PNSAMDKERRKSLLKPKLLRLQRDIEKASKDKEGLERMLKTYSSTSSFSDAKSQKDTAALMDENNLKLDLLEANSYKLSSMLAELEQRPQ
PSHPCSNSIFRWREKEHTHSYVKISRPFLMKRLENIVSKASSGGQSNPGSSTPAPGAAQLSSRLCKALYSFQARQDDELNLEKGDIVIIH

--------------------------------------------------------------

>16003_16003_28_CERS6-NOSTRIN_CERS6_chr2_169404211_ENST00000305747_NOSTRIN_chr2_169707594_ENST00000458381_length(amino acids)=488AA_BP=1
MAACVPRCLTRRRANQGGRPELPCDGQGGPFPQRGQREERTGARREPSRAAAAEEAAAAGGSSGGGGTGSGPAGRASPGALRGGELGGLR
VPQDRSGQSKMAGILAWFWNERFWLPHNVTWADLKNTEEATFPQAEDLYLAFPLAFCIFMVRLIFERFVAKPCAIALNIQANGPQIAPPN
AILEKVFTAITKSILELEKERIQLLCNNLNQYSQHISLFGQTLTTCHTQIHCAISKIDIEKDIQAVMEETAILSTENKSEFLLTDYFEED
PNSAMDKERRKSLLKPKLLRLQRDIEKASKDKEGLERMLKTYSSTSSFSDAKSQKDTAALMDENNLKLDLLEANSYKLSSMLAELEQRPQ
PSHPCSNSIFRWREKEHTHSYVKISRPFLMKRLENIVSKASSGGQSNPGSSTPAPGAAQLSSRLCKALYSFQARQDDELNLEKGDIVIIH

--------------------------------------------------------------

>16003_16003_29_CERS6-NOSTRIN_CERS6_chr2_169404211_ENST00000392687_NOSTRIN_chr2_169699501_ENST00000317647_length(amino acids)=450AA_BP=1
MRGGELGGLRVPQDRSGQSKMAGILAWFWNERFWLPHNVTWADLKNTEEATFPQAEDLYLAFPLAFCIFMVRLIFERFVAKPCAIALNIQ
ANGPQIAPPNAILEKVFTAITKLLNKLTKSTEKLEKEDENYYQKNMAGYSTRLKWENTLENCYQSILELEKERIQLLCNNLNQYSQHISL
FGQTLTTCHTQIHCAISKIDIEKDIQAVMEETAILSTENKSEFLLTDYFEEDPNSAMDKERRKSLLKPKLLRLQRDIEKASKDKEGLERM
LKTYSSTSSFSDAKSQKDTAALMDENNLKLDLLEANSYKLSSMLAELEQRPQPSHPCSNSIFRWREKEHTHSYVKISRPFLMKRLENIVS
KASSGGQSNPGSSTPAPGAAQLSSRLCKALYSFQARQDDELNLEKGDIVIIHEKKEGGWWFGSLNGKKGHFPAAYVEELPSNAGNTATKA

--------------------------------------------------------------

>16003_16003_30_CERS6-NOSTRIN_CERS6_chr2_169404211_ENST00000392687_NOSTRIN_chr2_169699501_ENST00000397206_length(amino acids)=451AA_BP=1
MRGGELGGLRVPQDRSGQSKMAGILAWFWNERFWLPHNVTWADLKNTEEATFPQAEDLYLAFPLAFCIFMVRLIFERFVAKPCAIALNIQ
ANGPQIAPPNAILEKVFTAITKLLNKLTKSTEKLEKEDENYYQKNMAGYSTRLKWENTLENCYQSILELEKERIQLLCNNLNQYSQHISL
FGQTLTTCHTQIHCAISKIDIEKDIQAVMEETAILSTENKSEFLLTDYFEEDPNSAMDKERRKSLLKPKLLRLQRDIEKASKDKEGLERM
LKTYSSTSSFSDAKSQKDTAALMDENNLKLDLLEANSYKLSSMLAELEQRPQPSHPCSNSIFRWREKEHTHSYVKISRPFLMKRLENIVS
KASSGGQSNPGSSTPAPGAAQLSSRLCKALYSFQARQDDELNLEKGDIVIIHEKKEGGWWFGSLNGKKGHFPAAYVEELPSNAGNTATKA

--------------------------------------------------------------

>16003_16003_31_CERS6-NOSTRIN_CERS6_chr2_169404211_ENST00000392687_NOSTRIN_chr2_169699501_ENST00000397209_length(amino acids)=451AA_BP=1
MRGGELGGLRVPQDRSGQSKMAGILAWFWNERFWLPHNVTWADLKNTEEATFPQAEDLYLAFPLAFCIFMVRLIFERFVAKPCAIALNIQ
ANGPQIAPPNAILEKVFTAITKLLNKLTKSTEKLEKEDENYYQKNMAGYSTRLKWENTLENCYQSILELEKERIQLLCNNLNQYSQHISL
FGQTLTTCHTQIHCAISKIDIEKDIQAVMEETAILSTENKSEFLLTDYFEEDPNSAMDKERRKSLLKPKLLRLQRDIEKASKDKEGLERM
LKTYSSTSSFSDAKSQKDTAALMDENNLKLDLLEANSYKLSSMLAELEQRPQPSHPCSNSIFRWREKEHTHSYVKISRPFLMKRLENIVS
KASSGGQSNPGSSTPAPGAAQLSSRLCKALYSFQARQDDELNLEKGDIVIIHEKKEGGWWFGSLNGKKGHFPAAYVEELPSNAGNTATKA

--------------------------------------------------------------

>16003_16003_32_CERS6-NOSTRIN_CERS6_chr2_169404211_ENST00000392687_NOSTRIN_chr2_169699501_ENST00000421711_length(amino acids)=451AA_BP=1
MRGGELGGLRVPQDRSGQSKMAGILAWFWNERFWLPHNVTWADLKNTEEATFPQAEDLYLAFPLAFCIFMVRLIFERFVAKPCAIALNIQ
ANGPQIAPPNAILEKVFTAITKLLNKLTKSTEKLEKEDENYYQKNMAGYSTRLKWENTLENCYQSILELEKERIQLLCNNLNQYSQHISL
FGQTLTTCHTQIHCAISKIDIEKDIQAVMEETAILSTENKSEFLLTDYFEEDPNSAMDKERRKSLLKPKLLRLQRDIEKASKDKEGLERM
LKTYSSTSSFSDAKSQKDTAALMDENNLKLDLLEANSYKLSSMLAELEQRPQPSHPCSNSIFRWREKEHTHSYVKISRPFLMKRLENIVS
KASSGGQSNPGSSTPAPGAAQLSSRLCKALYSFQARQDDELNLEKGDIVIIHEKKEGGWWFGSLNGKKGHFPAAYVEELPSNAGNTATKA

--------------------------------------------------------------

>16003_16003_33_CERS6-NOSTRIN_CERS6_chr2_169404211_ENST00000392687_NOSTRIN_chr2_169699501_ENST00000444448_length(amino acids)=507AA_BP=1
MRGGELGGLRVPQDRSGQSKMAGILAWFWNERFWLPHNVTWADLKNTEEATFPQAEDLYLAFPLAFCIFMVRLIFERFVAKPCAIALNIQ
ANGPQIAPPNAILEKVFTAITKLLNKLTKSTEKLEKEDENYYQKNMAGYSTRLKWENTLENCYQVTHSICLYAFWVKRAWGKCVSDLRYQ
DTFLPGNLPPLWFGYDIVKRLIMRLCSVCLQSILELEKERIQLLCNNLNQYSQHISLFGQTLTTCHTQIHCAISKIDIEKDIQAVMEETA
ILSTENKSEFLLTDYFEEDPNSAMDKERRKSLLKPKLLRLQRDIEKASKDKEGLERMLKTYSSTSSFSDAKSQKDTAALMDENNLKLDLL
EANSYKLSSMLAELEQRPQPSHPCSNSIFRWREKEHTHSYVKISRPFLMKRLENIVSKASSGGQSNPGSSTPAPGAAQLSSRLCKALYSF

--------------------------------------------------------------

>16003_16003_34_CERS6-NOSTRIN_CERS6_chr2_169404211_ENST00000392687_NOSTRIN_chr2_169699501_ENST00000445023_length(amino acids)=450AA_BP=1
MRGGELGGLRVPQDRSGQSKMAGILAWFWNERFWLPHNVTWADLKNTEEATFPQAEDLYLAFPLAFCIFMVRLIFERFVAKPCAIALNIQ
ANGPQIAPPNAILEKVFTAITKLLNKLTKSTEKLEKEDENYYQKNMAGYSTRLKWENTLENCYQSILELEKERIQLLCNNLNQYSQHISL
FGQTLTTCHTQIHCAISKIDIEKDIQAVMEETAILSTENKSEFLLTDYFEEDPNSAMDKERRKSLLKPKLLRLQRDIEKASKDKEGLERM
LKTYSSTSSFSDAKSQKDTAALMDENNLKLDLLEANSYKLSSMLAELEQRPQPSHPCSNSIFRWREKEHTHSYVKISRPFLMKRLENIVS
KASSGGQSNPGSSTPAPGAAQLSSRLCKALYSFQARQDDELNLEKGDIVIIHEKKEGGWWFGSLNGKKGHFPAAYVEELPSNAGNTATKA

--------------------------------------------------------------

>16003_16003_35_CERS6-NOSTRIN_CERS6_chr2_169404211_ENST00000392687_NOSTRIN_chr2_169699501_ENST00000458381_length(amino acids)=507AA_BP=1
MRGGELGGLRVPQDRSGQSKMAGILAWFWNERFWLPHNVTWADLKNTEEATFPQAEDLYLAFPLAFCIFMVRLIFERFVAKPCAIALNIQ
ANGPQIAPPNAILEKVFTAITKLLNKLTKSTEKLEKEDENYYQKNMAGYSTRLKWENTLENCYQVTHSICLYAFWVKRAWGKCVSDLRYQ
DTFLPGNLPPLWFGYDIVKRLIMRLCSVCLQSILELEKERIQLLCNNLNQYSQHISLFGQTLTTCHTQIHCAISKIDIEKDIQAVMEETA
ILSTENKSEFLLTDYFEEDPNSAMDKERRKSLLKPKLLRLQRDIEKASKDKEGLERMLKTYSSTSSFSDAKSQKDTAALMDENNLKLDLL
EANSYKLSSMLAELEQRPQPSHPCSNSIFRWREKEHTHSYVKISRPFLMKRLENIVSKASSGGQSNPGSSTPAPGAAQLSSRLCKALYSF

--------------------------------------------------------------

>16003_16003_36_CERS6-NOSTRIN_CERS6_chr2_169404211_ENST00000392687_NOSTRIN_chr2_169699502_ENST00000317647_length(amino acids)=450AA_BP=1
MRGGELGGLRVPQDRSGQSKMAGILAWFWNERFWLPHNVTWADLKNTEEATFPQAEDLYLAFPLAFCIFMVRLIFERFVAKPCAIALNIQ
ANGPQIAPPNAILEKVFTAITKLLNKLTKSTEKLEKEDENYYQKNMAGYSTRLKWENTLENCYQSILELEKERIQLLCNNLNQYSQHISL
FGQTLTTCHTQIHCAISKIDIEKDIQAVMEETAILSTENKSEFLLTDYFEEDPNSAMDKERRKSLLKPKLLRLQRDIEKASKDKEGLERM
LKTYSSTSSFSDAKSQKDTAALMDENNLKLDLLEANSYKLSSMLAELEQRPQPSHPCSNSIFRWREKEHTHSYVKISRPFLMKRLENIVS
KASSGGQSNPGSSTPAPGAAQLSSRLCKALYSFQARQDDELNLEKGDIVIIHEKKEGGWWFGSLNGKKGHFPAAYVEELPSNAGNTATKA

--------------------------------------------------------------

>16003_16003_37_CERS6-NOSTRIN_CERS6_chr2_169404211_ENST00000392687_NOSTRIN_chr2_169699502_ENST00000397206_length(amino acids)=451AA_BP=1
MRGGELGGLRVPQDRSGQSKMAGILAWFWNERFWLPHNVTWADLKNTEEATFPQAEDLYLAFPLAFCIFMVRLIFERFVAKPCAIALNIQ
ANGPQIAPPNAILEKVFTAITKLLNKLTKSTEKLEKEDENYYQKNMAGYSTRLKWENTLENCYQSILELEKERIQLLCNNLNQYSQHISL
FGQTLTTCHTQIHCAISKIDIEKDIQAVMEETAILSTENKSEFLLTDYFEEDPNSAMDKERRKSLLKPKLLRLQRDIEKASKDKEGLERM
LKTYSSTSSFSDAKSQKDTAALMDENNLKLDLLEANSYKLSSMLAELEQRPQPSHPCSNSIFRWREKEHTHSYVKISRPFLMKRLENIVS
KASSGGQSNPGSSTPAPGAAQLSSRLCKALYSFQARQDDELNLEKGDIVIIHEKKEGGWWFGSLNGKKGHFPAAYVEELPSNAGNTATKA

--------------------------------------------------------------

>16003_16003_38_CERS6-NOSTRIN_CERS6_chr2_169404211_ENST00000392687_NOSTRIN_chr2_169699502_ENST00000397209_length(amino acids)=451AA_BP=1
MRGGELGGLRVPQDRSGQSKMAGILAWFWNERFWLPHNVTWADLKNTEEATFPQAEDLYLAFPLAFCIFMVRLIFERFVAKPCAIALNIQ
ANGPQIAPPNAILEKVFTAITKLLNKLTKSTEKLEKEDENYYQKNMAGYSTRLKWENTLENCYQSILELEKERIQLLCNNLNQYSQHISL
FGQTLTTCHTQIHCAISKIDIEKDIQAVMEETAILSTENKSEFLLTDYFEEDPNSAMDKERRKSLLKPKLLRLQRDIEKASKDKEGLERM
LKTYSSTSSFSDAKSQKDTAALMDENNLKLDLLEANSYKLSSMLAELEQRPQPSHPCSNSIFRWREKEHTHSYVKISRPFLMKRLENIVS
KASSGGQSNPGSSTPAPGAAQLSSRLCKALYSFQARQDDELNLEKGDIVIIHEKKEGGWWFGSLNGKKGHFPAAYVEELPSNAGNTATKA

--------------------------------------------------------------

>16003_16003_39_CERS6-NOSTRIN_CERS6_chr2_169404211_ENST00000392687_NOSTRIN_chr2_169699502_ENST00000421711_length(amino acids)=451AA_BP=1
MRGGELGGLRVPQDRSGQSKMAGILAWFWNERFWLPHNVTWADLKNTEEATFPQAEDLYLAFPLAFCIFMVRLIFERFVAKPCAIALNIQ
ANGPQIAPPNAILEKVFTAITKLLNKLTKSTEKLEKEDENYYQKNMAGYSTRLKWENTLENCYQSILELEKERIQLLCNNLNQYSQHISL
FGQTLTTCHTQIHCAISKIDIEKDIQAVMEETAILSTENKSEFLLTDYFEEDPNSAMDKERRKSLLKPKLLRLQRDIEKASKDKEGLERM
LKTYSSTSSFSDAKSQKDTAALMDENNLKLDLLEANSYKLSSMLAELEQRPQPSHPCSNSIFRWREKEHTHSYVKISRPFLMKRLENIVS
KASSGGQSNPGSSTPAPGAAQLSSRLCKALYSFQARQDDELNLEKGDIVIIHEKKEGGWWFGSLNGKKGHFPAAYVEELPSNAGNTATKA

--------------------------------------------------------------

>16003_16003_40_CERS6-NOSTRIN_CERS6_chr2_169404211_ENST00000392687_NOSTRIN_chr2_169699502_ENST00000444448_length(amino acids)=507AA_BP=1
MRGGELGGLRVPQDRSGQSKMAGILAWFWNERFWLPHNVTWADLKNTEEATFPQAEDLYLAFPLAFCIFMVRLIFERFVAKPCAIALNIQ
ANGPQIAPPNAILEKVFTAITKLLNKLTKSTEKLEKEDENYYQKNMAGYSTRLKWENTLENCYQVTHSICLYAFWVKRAWGKCVSDLRYQ
DTFLPGNLPPLWFGYDIVKRLIMRLCSVCLQSILELEKERIQLLCNNLNQYSQHISLFGQTLTTCHTQIHCAISKIDIEKDIQAVMEETA
ILSTENKSEFLLTDYFEEDPNSAMDKERRKSLLKPKLLRLQRDIEKASKDKEGLERMLKTYSSTSSFSDAKSQKDTAALMDENNLKLDLL
EANSYKLSSMLAELEQRPQPSHPCSNSIFRWREKEHTHSYVKISRPFLMKRLENIVSKASSGGQSNPGSSTPAPGAAQLSSRLCKALYSF

--------------------------------------------------------------

>16003_16003_41_CERS6-NOSTRIN_CERS6_chr2_169404211_ENST00000392687_NOSTRIN_chr2_169699502_ENST00000445023_length(amino acids)=450AA_BP=1
MRGGELGGLRVPQDRSGQSKMAGILAWFWNERFWLPHNVTWADLKNTEEATFPQAEDLYLAFPLAFCIFMVRLIFERFVAKPCAIALNIQ
ANGPQIAPPNAILEKVFTAITKLLNKLTKSTEKLEKEDENYYQKNMAGYSTRLKWENTLENCYQSILELEKERIQLLCNNLNQYSQHISL
FGQTLTTCHTQIHCAISKIDIEKDIQAVMEETAILSTENKSEFLLTDYFEEDPNSAMDKERRKSLLKPKLLRLQRDIEKASKDKEGLERM
LKTYSSTSSFSDAKSQKDTAALMDENNLKLDLLEANSYKLSSMLAELEQRPQPSHPCSNSIFRWREKEHTHSYVKISRPFLMKRLENIVS
KASSGGQSNPGSSTPAPGAAQLSSRLCKALYSFQARQDDELNLEKGDIVIIHEKKEGGWWFGSLNGKKGHFPAAYVEELPSNAGNTATKA

--------------------------------------------------------------

>16003_16003_42_CERS6-NOSTRIN_CERS6_chr2_169404211_ENST00000392687_NOSTRIN_chr2_169699502_ENST00000458381_length(amino acids)=507AA_BP=1
MRGGELGGLRVPQDRSGQSKMAGILAWFWNERFWLPHNVTWADLKNTEEATFPQAEDLYLAFPLAFCIFMVRLIFERFVAKPCAIALNIQ
ANGPQIAPPNAILEKVFTAITKLLNKLTKSTEKLEKEDENYYQKNMAGYSTRLKWENTLENCYQVTHSICLYAFWVKRAWGKCVSDLRYQ
DTFLPGNLPPLWFGYDIVKRLIMRLCSVCLQSILELEKERIQLLCNNLNQYSQHISLFGQTLTTCHTQIHCAISKIDIEKDIQAVMEETA
ILSTENKSEFLLTDYFEEDPNSAMDKERRKSLLKPKLLRLQRDIEKASKDKEGLERMLKTYSSTSSFSDAKSQKDTAALMDENNLKLDLL
EANSYKLSSMLAELEQRPQPSHPCSNSIFRWREKEHTHSYVKISRPFLMKRLENIVSKASSGGQSNPGSSTPAPGAAQLSSRLCKALYSF

--------------------------------------------------------------

>16003_16003_43_CERS6-NOSTRIN_CERS6_chr2_169404211_ENST00000392687_NOSTRIN_chr2_169707593_ENST00000317647_length(amino acids)=408AA_BP=1
MRGGELGGLRVPQDRSGQSKMAGILAWFWNERFWLPHNVTWADLKNTEEATFPQAEDLYLAFPLAFCIFMVRLIFERFVAKPCAIALNIQ
ANGPQIAPPNAILEKVFTAITKSILELEKERIQLLCNNLNQYSQHISLFGQTLTTCHTQIHCAISKIDIEKDIQAVMEETAILSTENKSE
FLLTDYFEEDPNSAMDKERRKSLLKPKLLRLQRDIEKASKDKEGLERMLKTYSSTSSFSDAKSQKDTAALMDENNLKLDLLEANSYKLSS
MLAELEQRPQPSHPCSNSIFRWREKEHTHSYVKISRPFLMKRLENIVSKASSGGQSNPGSSTPAPGAAQLSSRLCKALYSFQARQDDELN

--------------------------------------------------------------

>16003_16003_44_CERS6-NOSTRIN_CERS6_chr2_169404211_ENST00000392687_NOSTRIN_chr2_169707593_ENST00000397206_length(amino acids)=409AA_BP=1
MRGGELGGLRVPQDRSGQSKMAGILAWFWNERFWLPHNVTWADLKNTEEATFPQAEDLYLAFPLAFCIFMVRLIFERFVAKPCAIALNIQ
ANGPQIAPPNAILEKVFTAITKSILELEKERIQLLCNNLNQYSQHISLFGQTLTTCHTQIHCAISKIDIEKDIQAVMEETAILSTENKSE
FLLTDYFEEDPNSAMDKERRKSLLKPKLLRLQRDIEKASKDKEGLERMLKTYSSTSSFSDAKSQKDTAALMDENNLKLDLLEANSYKLSS
MLAELEQRPQPSHPCSNSIFRWREKEHTHSYVKISRPFLMKRLENIVSKASSGGQSNPGSSTPAPGAAQLSSRLCKALYSFQARQDDELN

--------------------------------------------------------------

>16003_16003_45_CERS6-NOSTRIN_CERS6_chr2_169404211_ENST00000392687_NOSTRIN_chr2_169707593_ENST00000397209_length(amino acids)=409AA_BP=1
MRGGELGGLRVPQDRSGQSKMAGILAWFWNERFWLPHNVTWADLKNTEEATFPQAEDLYLAFPLAFCIFMVRLIFERFVAKPCAIALNIQ
ANGPQIAPPNAILEKVFTAITKSILELEKERIQLLCNNLNQYSQHISLFGQTLTTCHTQIHCAISKIDIEKDIQAVMEETAILSTENKSE
FLLTDYFEEDPNSAMDKERRKSLLKPKLLRLQRDIEKASKDKEGLERMLKTYSSTSSFSDAKSQKDTAALMDENNLKLDLLEANSYKLSS
MLAELEQRPQPSHPCSNSIFRWREKEHTHSYVKISRPFLMKRLENIVSKASSGGQSNPGSSTPAPGAAQLSSRLCKALYSFQARQDDELN

--------------------------------------------------------------

>16003_16003_46_CERS6-NOSTRIN_CERS6_chr2_169404211_ENST00000392687_NOSTRIN_chr2_169707593_ENST00000421711_length(amino acids)=409AA_BP=1
MRGGELGGLRVPQDRSGQSKMAGILAWFWNERFWLPHNVTWADLKNTEEATFPQAEDLYLAFPLAFCIFMVRLIFERFVAKPCAIALNIQ
ANGPQIAPPNAILEKVFTAITKSILELEKERIQLLCNNLNQYSQHISLFGQTLTTCHTQIHCAISKIDIEKDIQAVMEETAILSTENKSE
FLLTDYFEEDPNSAMDKERRKSLLKPKLLRLQRDIEKASKDKEGLERMLKTYSSTSSFSDAKSQKDTAALMDENNLKLDLLEANSYKLSS
MLAELEQRPQPSHPCSNSIFRWREKEHTHSYVKISRPFLMKRLENIVSKASSGGQSNPGSSTPAPGAAQLSSRLCKALYSFQARQDDELN

--------------------------------------------------------------

>16003_16003_47_CERS6-NOSTRIN_CERS6_chr2_169404211_ENST00000392687_NOSTRIN_chr2_169707593_ENST00000444448_length(amino acids)=408AA_BP=1
MRGGELGGLRVPQDRSGQSKMAGILAWFWNERFWLPHNVTWADLKNTEEATFPQAEDLYLAFPLAFCIFMVRLIFERFVAKPCAIALNIQ
ANGPQIAPPNAILEKVFTAITKSILELEKERIQLLCNNLNQYSQHISLFGQTLTTCHTQIHCAISKIDIEKDIQAVMEETAILSTENKSE
FLLTDYFEEDPNSAMDKERRKSLLKPKLLRLQRDIEKASKDKEGLERMLKTYSSTSSFSDAKSQKDTAALMDENNLKLDLLEANSYKLSS
MLAELEQRPQPSHPCSNSIFRWREKEHTHSYVKISRPFLMKRLENIVSKASSGGQSNPGSSTPAPGAAQLSSRLCKALYSFQARQDDELN

--------------------------------------------------------------

>16003_16003_48_CERS6-NOSTRIN_CERS6_chr2_169404211_ENST00000392687_NOSTRIN_chr2_169707593_ENST00000445023_length(amino acids)=408AA_BP=1
MRGGELGGLRVPQDRSGQSKMAGILAWFWNERFWLPHNVTWADLKNTEEATFPQAEDLYLAFPLAFCIFMVRLIFERFVAKPCAIALNIQ
ANGPQIAPPNAILEKVFTAITKSILELEKERIQLLCNNLNQYSQHISLFGQTLTTCHTQIHCAISKIDIEKDIQAVMEETAILSTENKSE
FLLTDYFEEDPNSAMDKERRKSLLKPKLLRLQRDIEKASKDKEGLERMLKTYSSTSSFSDAKSQKDTAALMDENNLKLDLLEANSYKLSS
MLAELEQRPQPSHPCSNSIFRWREKEHTHSYVKISRPFLMKRLENIVSKASSGGQSNPGSSTPAPGAAQLSSRLCKALYSFQARQDDELN

--------------------------------------------------------------

>16003_16003_49_CERS6-NOSTRIN_CERS6_chr2_169404211_ENST00000392687_NOSTRIN_chr2_169707593_ENST00000458381_length(amino acids)=408AA_BP=1
MRGGELGGLRVPQDRSGQSKMAGILAWFWNERFWLPHNVTWADLKNTEEATFPQAEDLYLAFPLAFCIFMVRLIFERFVAKPCAIALNIQ
ANGPQIAPPNAILEKVFTAITKSILELEKERIQLLCNNLNQYSQHISLFGQTLTTCHTQIHCAISKIDIEKDIQAVMEETAILSTENKSE
FLLTDYFEEDPNSAMDKERRKSLLKPKLLRLQRDIEKASKDKEGLERMLKTYSSTSSFSDAKSQKDTAALMDENNLKLDLLEANSYKLSS
MLAELEQRPQPSHPCSNSIFRWREKEHTHSYVKISRPFLMKRLENIVSKASSGGQSNPGSSTPAPGAAQLSSRLCKALYSFQARQDDELN

--------------------------------------------------------------

>16003_16003_50_CERS6-NOSTRIN_CERS6_chr2_169404211_ENST00000392687_NOSTRIN_chr2_169707594_ENST00000317647_length(amino acids)=408AA_BP=1
MRGGELGGLRVPQDRSGQSKMAGILAWFWNERFWLPHNVTWADLKNTEEATFPQAEDLYLAFPLAFCIFMVRLIFERFVAKPCAIALNIQ
ANGPQIAPPNAILEKVFTAITKSILELEKERIQLLCNNLNQYSQHISLFGQTLTTCHTQIHCAISKIDIEKDIQAVMEETAILSTENKSE
FLLTDYFEEDPNSAMDKERRKSLLKPKLLRLQRDIEKASKDKEGLERMLKTYSSTSSFSDAKSQKDTAALMDENNLKLDLLEANSYKLSS
MLAELEQRPQPSHPCSNSIFRWREKEHTHSYVKISRPFLMKRLENIVSKASSGGQSNPGSSTPAPGAAQLSSRLCKALYSFQARQDDELN

--------------------------------------------------------------

>16003_16003_51_CERS6-NOSTRIN_CERS6_chr2_169404211_ENST00000392687_NOSTRIN_chr2_169707594_ENST00000397206_length(amino acids)=409AA_BP=1
MRGGELGGLRVPQDRSGQSKMAGILAWFWNERFWLPHNVTWADLKNTEEATFPQAEDLYLAFPLAFCIFMVRLIFERFVAKPCAIALNIQ
ANGPQIAPPNAILEKVFTAITKSILELEKERIQLLCNNLNQYSQHISLFGQTLTTCHTQIHCAISKIDIEKDIQAVMEETAILSTENKSE
FLLTDYFEEDPNSAMDKERRKSLLKPKLLRLQRDIEKASKDKEGLERMLKTYSSTSSFSDAKSQKDTAALMDENNLKLDLLEANSYKLSS
MLAELEQRPQPSHPCSNSIFRWREKEHTHSYVKISRPFLMKRLENIVSKASSGGQSNPGSSTPAPGAAQLSSRLCKALYSFQARQDDELN

--------------------------------------------------------------

>16003_16003_52_CERS6-NOSTRIN_CERS6_chr2_169404211_ENST00000392687_NOSTRIN_chr2_169707594_ENST00000397209_length(amino acids)=409AA_BP=1
MRGGELGGLRVPQDRSGQSKMAGILAWFWNERFWLPHNVTWADLKNTEEATFPQAEDLYLAFPLAFCIFMVRLIFERFVAKPCAIALNIQ
ANGPQIAPPNAILEKVFTAITKSILELEKERIQLLCNNLNQYSQHISLFGQTLTTCHTQIHCAISKIDIEKDIQAVMEETAILSTENKSE
FLLTDYFEEDPNSAMDKERRKSLLKPKLLRLQRDIEKASKDKEGLERMLKTYSSTSSFSDAKSQKDTAALMDENNLKLDLLEANSYKLSS
MLAELEQRPQPSHPCSNSIFRWREKEHTHSYVKISRPFLMKRLENIVSKASSGGQSNPGSSTPAPGAAQLSSRLCKALYSFQARQDDELN

--------------------------------------------------------------

>16003_16003_53_CERS6-NOSTRIN_CERS6_chr2_169404211_ENST00000392687_NOSTRIN_chr2_169707594_ENST00000421711_length(amino acids)=409AA_BP=1
MRGGELGGLRVPQDRSGQSKMAGILAWFWNERFWLPHNVTWADLKNTEEATFPQAEDLYLAFPLAFCIFMVRLIFERFVAKPCAIALNIQ
ANGPQIAPPNAILEKVFTAITKSILELEKERIQLLCNNLNQYSQHISLFGQTLTTCHTQIHCAISKIDIEKDIQAVMEETAILSTENKSE
FLLTDYFEEDPNSAMDKERRKSLLKPKLLRLQRDIEKASKDKEGLERMLKTYSSTSSFSDAKSQKDTAALMDENNLKLDLLEANSYKLSS
MLAELEQRPQPSHPCSNSIFRWREKEHTHSYVKISRPFLMKRLENIVSKASSGGQSNPGSSTPAPGAAQLSSRLCKALYSFQARQDDELN

--------------------------------------------------------------

>16003_16003_54_CERS6-NOSTRIN_CERS6_chr2_169404211_ENST00000392687_NOSTRIN_chr2_169707594_ENST00000444448_length(amino acids)=408AA_BP=1
MRGGELGGLRVPQDRSGQSKMAGILAWFWNERFWLPHNVTWADLKNTEEATFPQAEDLYLAFPLAFCIFMVRLIFERFVAKPCAIALNIQ
ANGPQIAPPNAILEKVFTAITKSILELEKERIQLLCNNLNQYSQHISLFGQTLTTCHTQIHCAISKIDIEKDIQAVMEETAILSTENKSE
FLLTDYFEEDPNSAMDKERRKSLLKPKLLRLQRDIEKASKDKEGLERMLKTYSSTSSFSDAKSQKDTAALMDENNLKLDLLEANSYKLSS
MLAELEQRPQPSHPCSNSIFRWREKEHTHSYVKISRPFLMKRLENIVSKASSGGQSNPGSSTPAPGAAQLSSRLCKALYSFQARQDDELN

--------------------------------------------------------------

>16003_16003_55_CERS6-NOSTRIN_CERS6_chr2_169404211_ENST00000392687_NOSTRIN_chr2_169707594_ENST00000445023_length(amino acids)=408AA_BP=1
MRGGELGGLRVPQDRSGQSKMAGILAWFWNERFWLPHNVTWADLKNTEEATFPQAEDLYLAFPLAFCIFMVRLIFERFVAKPCAIALNIQ
ANGPQIAPPNAILEKVFTAITKSILELEKERIQLLCNNLNQYSQHISLFGQTLTTCHTQIHCAISKIDIEKDIQAVMEETAILSTENKSE
FLLTDYFEEDPNSAMDKERRKSLLKPKLLRLQRDIEKASKDKEGLERMLKTYSSTSSFSDAKSQKDTAALMDENNLKLDLLEANSYKLSS
MLAELEQRPQPSHPCSNSIFRWREKEHTHSYVKISRPFLMKRLENIVSKASSGGQSNPGSSTPAPGAAQLSSRLCKALYSFQARQDDELN

--------------------------------------------------------------

>16003_16003_56_CERS6-NOSTRIN_CERS6_chr2_169404211_ENST00000392687_NOSTRIN_chr2_169707594_ENST00000458381_length(amino acids)=408AA_BP=1
MRGGELGGLRVPQDRSGQSKMAGILAWFWNERFWLPHNVTWADLKNTEEATFPQAEDLYLAFPLAFCIFMVRLIFERFVAKPCAIALNIQ
ANGPQIAPPNAILEKVFTAITKSILELEKERIQLLCNNLNQYSQHISLFGQTLTTCHTQIHCAISKIDIEKDIQAVMEETAILSTENKSE
FLLTDYFEEDPNSAMDKERRKSLLKPKLLRLQRDIEKASKDKEGLERMLKTYSSTSSFSDAKSQKDTAALMDENNLKLDLLEANSYKLSS
MLAELEQRPQPSHPCSNSIFRWREKEHTHSYVKISRPFLMKRLENIVSKASSGGQSNPGSSTPAPGAAQLSSRLCKALYSFQARQDDELN

--------------------------------------------------------------

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Fusion Protein Functional Features


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr2:169404211/chr2:169699501)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
CERS6

Q6ZMG9

NOSTRIN

Q8IVI9

FUNCTION: Ceramide synthase that catalyzes formation of ceramide from sphinganine and acyl-CoA substrates, with high selectivity toward palmitoyl-CoA (hexadecanoyl-CoA; C16:0-CoA) as acyl donor (PubMed:17977534, PubMed:17609214, PubMed:23530041, PubMed:26887952, PubMed:31916624). Can use other acyl donors, but with less efficiency (By similarity). Ceramides generated by CERS6 play a role in inflammatory response (By similarity). Acts as a regulator of metabolism and hepatic lipid accumulation (By similarity). Under high fat diet, palmitoyl- (C16:0-) ceramides generated by CERS6 specifically bind the mitochondrial fission factor MFF, thereby promoting mitochondrial fragmentation and contributing to the development of obesity (By similarity). {ECO:0000250|UniProtKB:Q8C172, ECO:0000269|PubMed:17609214, ECO:0000269|PubMed:17977534, ECO:0000269|PubMed:23530041, ECO:0000269|PubMed:26887952, ECO:0000269|PubMed:31916624}.FUNCTION: Multivalent adapter protein which may decrease NOS3 activity by inducing its translocation away from the plasma membrane. {ECO:0000269|PubMed:12446846, ECO:0000269|PubMed:16234328, ECO:0000269|PubMed:16807357}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

* Minus value of BPloci means that the break pointn is located before the CDS.
- Retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCERS6chr2:169404211chr2:169699501ENST00000305747+2101_3492.0385.0Topological domainLumenal
HgeneCERS6chr2:169404211chr2:169699501ENST00000392687+2111_3492.0393.0Topological domainLumenal
HgeneCERS6chr2:169404211chr2:169699502ENST00000305747+2101_3492.0385.0Topological domainLumenal
HgeneCERS6chr2:169404211chr2:169699502ENST00000392687+2111_3492.0393.0Topological domainLumenal
HgeneCERS6chr2:169404211chr2:169707593ENST00000305747+2101_3492.0385.0Topological domainLumenal
HgeneCERS6chr2:169404211chr2:169707593ENST00000392687+2111_3492.0393.0Topological domainLumenal
HgeneCERS6chr2:169404211chr2:169707594ENST00000305747+2101_3492.0385.0Topological domainLumenal
HgeneCERS6chr2:169404211chr2:169707594ENST00000392687+2111_3492.0393.0Topological domainLumenal
HgeneCERS6chr2:169404211chr2:169699501ENST00000305747+21035_5592.0385.0TransmembraneHelical
HgeneCERS6chr2:169404211chr2:169699501ENST00000392687+21135_5592.0393.0TransmembraneHelical
HgeneCERS6chr2:169404211chr2:169699502ENST00000305747+21035_5592.0385.0TransmembraneHelical
HgeneCERS6chr2:169404211chr2:169699502ENST00000392687+21135_5592.0393.0TransmembraneHelical
HgeneCERS6chr2:169404211chr2:169707593ENST00000305747+21035_5592.0385.0TransmembraneHelical
HgeneCERS6chr2:169404211chr2:169707593ENST00000392687+21135_5592.0393.0TransmembraneHelical
HgeneCERS6chr2:169404211chr2:169707594ENST00000305747+21035_5592.0385.0TransmembraneHelical
HgeneCERS6chr2:169404211chr2:169707594ENST00000392687+21135_5592.0393.0TransmembraneHelical
TgeneNOSTRINchr2:169404211chr2:169699501ENST00000397206515160_22290.0429.0Coiled coilOntology_term=ECO:0000255
TgeneNOSTRINchr2:169404211chr2:169699501ENST00000397209515160_222140.0479.0Coiled coilOntology_term=ECO:0000255
TgeneNOSTRINchr2:169404211chr2:169699501ENST00000421711515160_222140.0479.0Coiled coilOntology_term=ECO:0000255
TgeneNOSTRINchr2:169404211chr2:169699501ENST00000445023515160_22290.0429.0Coiled coilOntology_term=ECO:0000255
TgeneNOSTRINchr2:169404211chr2:169699502ENST00000397206515160_22290.0429.0Coiled coilOntology_term=ECO:0000255
TgeneNOSTRINchr2:169404211chr2:169699502ENST00000397209515160_222140.0479.0Coiled coilOntology_term=ECO:0000255
TgeneNOSTRINchr2:169404211chr2:169699502ENST00000421711515160_222140.0479.0Coiled coilOntology_term=ECO:0000255
TgeneNOSTRINchr2:169404211chr2:169699502ENST00000445023515160_22290.0429.0Coiled coilOntology_term=ECO:0000255
TgeneNOSTRINchr2:169404211chr2:169707593ENST00000397206615160_222132.0429.0Coiled coilOntology_term=ECO:0000255
TgeneNOSTRINchr2:169404211chr2:169707593ENST00000445023615160_222132.0429.0Coiled coilOntology_term=ECO:0000255
TgeneNOSTRINchr2:169404211chr2:169707594ENST00000397206615160_222132.0429.0Coiled coilOntology_term=ECO:0000255
TgeneNOSTRINchr2:169404211chr2:169707594ENST00000445023615160_222132.0429.0Coiled coilOntology_term=ECO:0000255
TgeneNOSTRINchr2:169404211chr2:169699501ENST00000317647616292_372168.0507.0DomainREM-1
TgeneNOSTRINchr2:169404211chr2:169699501ENST00000317647616438_497168.0507.0DomainSH3
TgeneNOSTRINchr2:169404211chr2:169699501ENST00000397206515292_37290.0429.0DomainREM-1
TgeneNOSTRINchr2:169404211chr2:169699501ENST00000397206515438_49790.0429.0DomainSH3
TgeneNOSTRINchr2:169404211chr2:169699501ENST00000397209515292_372140.0479.0DomainREM-1
TgeneNOSTRINchr2:169404211chr2:169699501ENST00000397209515438_497140.0479.0DomainSH3
TgeneNOSTRINchr2:169404211chr2:169699501ENST00000421711515292_372140.0479.0DomainREM-1
TgeneNOSTRINchr2:169404211chr2:169699501ENST00000421711515438_497140.0479.0DomainSH3
TgeneNOSTRINchr2:169404211chr2:169699501ENST00000444448819292_372168.0564.0DomainREM-1
TgeneNOSTRINchr2:169404211chr2:169699501ENST00000444448819438_497168.0564.0DomainSH3
TgeneNOSTRINchr2:169404211chr2:169699501ENST00000445023515292_37290.0429.0DomainREM-1
TgeneNOSTRINchr2:169404211chr2:169699501ENST00000445023515438_49790.0429.0DomainSH3
TgeneNOSTRINchr2:169404211chr2:169699501ENST000004583811021292_372168.0564.0DomainREM-1
TgeneNOSTRINchr2:169404211chr2:169699501ENST000004583811021438_497168.0564.0DomainSH3
TgeneNOSTRINchr2:169404211chr2:169699502ENST00000317647616292_372168.0507.0DomainREM-1
TgeneNOSTRINchr2:169404211chr2:169699502ENST00000317647616438_497168.0507.0DomainSH3
TgeneNOSTRINchr2:169404211chr2:169699502ENST00000397206515292_37290.0429.0DomainREM-1
TgeneNOSTRINchr2:169404211chr2:169699502ENST00000397206515438_49790.0429.0DomainSH3
TgeneNOSTRINchr2:169404211chr2:169699502ENST00000397209515292_372140.0479.0DomainREM-1
TgeneNOSTRINchr2:169404211chr2:169699502ENST00000397209515438_497140.0479.0DomainSH3
TgeneNOSTRINchr2:169404211chr2:169699502ENST00000421711515292_372140.0479.0DomainREM-1
TgeneNOSTRINchr2:169404211chr2:169699502ENST00000421711515438_497140.0479.0DomainSH3
TgeneNOSTRINchr2:169404211chr2:169699502ENST00000444448819292_372168.0564.0DomainREM-1
TgeneNOSTRINchr2:169404211chr2:169699502ENST00000444448819438_497168.0564.0DomainSH3
TgeneNOSTRINchr2:169404211chr2:169699502ENST00000445023515292_37290.0429.0DomainREM-1
TgeneNOSTRINchr2:169404211chr2:169699502ENST00000445023515438_49790.0429.0DomainSH3
TgeneNOSTRINchr2:169404211chr2:169699502ENST000004583811021292_372168.0564.0DomainREM-1
TgeneNOSTRINchr2:169404211chr2:169699502ENST000004583811021438_497168.0564.0DomainSH3
TgeneNOSTRINchr2:169404211chr2:169707593ENST00000317647716292_372210.0507.0DomainREM-1
TgeneNOSTRINchr2:169404211chr2:169707593ENST00000317647716438_497210.0507.0DomainSH3
TgeneNOSTRINchr2:169404211chr2:169707593ENST00000397206615292_372132.0429.0DomainREM-1
TgeneNOSTRINchr2:169404211chr2:169707593ENST00000397206615438_497132.0429.0DomainSH3
TgeneNOSTRINchr2:169404211chr2:169707593ENST00000397209615292_372182.0479.0DomainREM-1
TgeneNOSTRINchr2:169404211chr2:169707593ENST00000397209615438_497182.0479.0DomainSH3
TgeneNOSTRINchr2:169404211chr2:169707593ENST00000421711615292_372182.0479.0DomainREM-1
TgeneNOSTRINchr2:169404211chr2:169707593ENST00000421711615438_497182.0479.0DomainSH3
TgeneNOSTRINchr2:169404211chr2:169707593ENST000004444481019292_372267.0564.0DomainREM-1
TgeneNOSTRINchr2:169404211chr2:169707593ENST000004444481019438_497267.0564.0DomainSH3
TgeneNOSTRINchr2:169404211chr2:169707593ENST00000445023615292_372132.0429.0DomainREM-1
TgeneNOSTRINchr2:169404211chr2:169707593ENST00000445023615438_497132.0429.0DomainSH3
TgeneNOSTRINchr2:169404211chr2:169707593ENST000004583811221292_372267.0564.0DomainREM-1
TgeneNOSTRINchr2:169404211chr2:169707593ENST000004583811221438_497267.0564.0DomainSH3
TgeneNOSTRINchr2:169404211chr2:169707594ENST00000317647716292_372210.0507.0DomainREM-1
TgeneNOSTRINchr2:169404211chr2:169707594ENST00000317647716438_497210.0507.0DomainSH3
TgeneNOSTRINchr2:169404211chr2:169707594ENST00000397206615292_372132.0429.0DomainREM-1
TgeneNOSTRINchr2:169404211chr2:169707594ENST00000397206615438_497132.0429.0DomainSH3
TgeneNOSTRINchr2:169404211chr2:169707594ENST00000397209615292_372182.0479.0DomainREM-1
TgeneNOSTRINchr2:169404211chr2:169707594ENST00000397209615438_497182.0479.0DomainSH3
TgeneNOSTRINchr2:169404211chr2:169707594ENST00000421711615292_372182.0479.0DomainREM-1
TgeneNOSTRINchr2:169404211chr2:169707594ENST00000421711615438_497182.0479.0DomainSH3
TgeneNOSTRINchr2:169404211chr2:169707594ENST000004444481019292_372267.0564.0DomainREM-1
TgeneNOSTRINchr2:169404211chr2:169707594ENST000004444481019438_497267.0564.0DomainSH3
TgeneNOSTRINchr2:169404211chr2:169707594ENST00000445023615292_372132.0429.0DomainREM-1
TgeneNOSTRINchr2:169404211chr2:169707594ENST00000445023615438_497132.0429.0DomainSH3
TgeneNOSTRINchr2:169404211chr2:169707594ENST000004583811221292_372267.0564.0DomainREM-1
TgeneNOSTRINchr2:169404211chr2:169707594ENST000004583811221438_497267.0564.0DomainSH3

- Not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCERS6chr2:169404211chr2:169699501ENST00000305747+210130_33192.0385.0DomainTLC
HgeneCERS6chr2:169404211chr2:169699501ENST00000392687+211130_33192.0393.0DomainTLC
HgeneCERS6chr2:169404211chr2:169699502ENST00000305747+210130_33192.0385.0DomainTLC
HgeneCERS6chr2:169404211chr2:169699502ENST00000392687+211130_33192.0393.0DomainTLC
HgeneCERS6chr2:169404211chr2:169707593ENST00000305747+210130_33192.0385.0DomainTLC
HgeneCERS6chr2:169404211chr2:169707593ENST00000392687+211130_33192.0393.0DomainTLC
HgeneCERS6chr2:169404211chr2:169707594ENST00000305747+210130_33192.0385.0DomainTLC
HgeneCERS6chr2:169404211chr2:169707594ENST00000392687+211130_33192.0393.0DomainTLC
HgeneCERS6chr2:169404211chr2:169699501ENST00000305747+21066_12792.0385.0RegionHomeobox-like
HgeneCERS6chr2:169404211chr2:169699501ENST00000392687+21166_12792.0393.0RegionHomeobox-like
HgeneCERS6chr2:169404211chr2:169699502ENST00000305747+21066_12792.0385.0RegionHomeobox-like
HgeneCERS6chr2:169404211chr2:169699502ENST00000392687+21166_12792.0393.0RegionHomeobox-like
HgeneCERS6chr2:169404211chr2:169707593ENST00000305747+21066_12792.0385.0RegionHomeobox-like
HgeneCERS6chr2:169404211chr2:169707593ENST00000392687+21166_12792.0393.0RegionHomeobox-like
HgeneCERS6chr2:169404211chr2:169707594ENST00000305747+21066_12792.0385.0RegionHomeobox-like
HgeneCERS6chr2:169404211chr2:169707594ENST00000392687+21166_12792.0393.0RegionHomeobox-like
HgeneCERS6chr2:169404211chr2:169699501ENST00000305747+210324_38492.0385.0Topological domainCytoplasmic
HgeneCERS6chr2:169404211chr2:169699501ENST00000392687+211324_38492.0393.0Topological domainCytoplasmic
HgeneCERS6chr2:169404211chr2:169699502ENST00000305747+210324_38492.0385.0Topological domainCytoplasmic
HgeneCERS6chr2:169404211chr2:169699502ENST00000392687+211324_38492.0393.0Topological domainCytoplasmic
HgeneCERS6chr2:169404211chr2:169707593ENST00000305747+210324_38492.0385.0Topological domainCytoplasmic
HgeneCERS6chr2:169404211chr2:169707593ENST00000392687+211324_38492.0393.0Topological domainCytoplasmic
HgeneCERS6chr2:169404211chr2:169707594ENST00000305747+210324_38492.0385.0Topological domainCytoplasmic
HgeneCERS6chr2:169404211chr2:169707594ENST00000392687+211324_38492.0393.0Topological domainCytoplasmic
HgeneCERS6chr2:169404211chr2:169699501ENST00000305747+210178_19892.0385.0TransmembraneHelical
HgeneCERS6chr2:169404211chr2:169699501ENST00000305747+210205_22592.0385.0TransmembraneHelical
HgeneCERS6chr2:169404211chr2:169699501ENST00000305747+210263_28392.0385.0TransmembraneHelical
HgeneCERS6chr2:169404211chr2:169699501ENST00000305747+210303_32392.0385.0TransmembraneHelical
HgeneCERS6chr2:169404211chr2:169699501ENST00000392687+211178_19892.0393.0TransmembraneHelical
HgeneCERS6chr2:169404211chr2:169699501ENST00000392687+211205_22592.0393.0TransmembraneHelical
HgeneCERS6chr2:169404211chr2:169699501ENST00000392687+211263_28392.0393.0TransmembraneHelical
HgeneCERS6chr2:169404211chr2:169699501ENST00000392687+211303_32392.0393.0TransmembraneHelical
HgeneCERS6chr2:169404211chr2:169699502ENST00000305747+210178_19892.0385.0TransmembraneHelical
HgeneCERS6chr2:169404211chr2:169699502ENST00000305747+210205_22592.0385.0TransmembraneHelical
HgeneCERS6chr2:169404211chr2:169699502ENST00000305747+210263_28392.0385.0TransmembraneHelical
HgeneCERS6chr2:169404211chr2:169699502ENST00000305747+210303_32392.0385.0TransmembraneHelical
HgeneCERS6chr2:169404211chr2:169699502ENST00000392687+211178_19892.0393.0TransmembraneHelical
HgeneCERS6chr2:169404211chr2:169699502ENST00000392687+211205_22592.0393.0TransmembraneHelical
HgeneCERS6chr2:169404211chr2:169699502ENST00000392687+211263_28392.0393.0TransmembraneHelical
HgeneCERS6chr2:169404211chr2:169699502ENST00000392687+211303_32392.0393.0TransmembraneHelical
HgeneCERS6chr2:169404211chr2:169707593ENST00000305747+210178_19892.0385.0TransmembraneHelical
HgeneCERS6chr2:169404211chr2:169707593ENST00000305747+210205_22592.0385.0TransmembraneHelical
HgeneCERS6chr2:169404211chr2:169707593ENST00000305747+210263_28392.0385.0TransmembraneHelical
HgeneCERS6chr2:169404211chr2:169707593ENST00000305747+210303_32392.0385.0TransmembraneHelical
HgeneCERS6chr2:169404211chr2:169707593ENST00000392687+211178_19892.0393.0TransmembraneHelical
HgeneCERS6chr2:169404211chr2:169707593ENST00000392687+211205_22592.0393.0TransmembraneHelical
HgeneCERS6chr2:169404211chr2:169707593ENST00000392687+211263_28392.0393.0TransmembraneHelical
HgeneCERS6chr2:169404211chr2:169707593ENST00000392687+211303_32392.0393.0TransmembraneHelical
HgeneCERS6chr2:169404211chr2:169707594ENST00000305747+210178_19892.0385.0TransmembraneHelical
HgeneCERS6chr2:169404211chr2:169707594ENST00000305747+210205_22592.0385.0TransmembraneHelical
HgeneCERS6chr2:169404211chr2:169707594ENST00000305747+210263_28392.0385.0TransmembraneHelical
HgeneCERS6chr2:169404211chr2:169707594ENST00000305747+210303_32392.0385.0TransmembraneHelical
HgeneCERS6chr2:169404211chr2:169707594ENST00000392687+211178_19892.0393.0TransmembraneHelical
HgeneCERS6chr2:169404211chr2:169707594ENST00000392687+211205_22592.0393.0TransmembraneHelical
HgeneCERS6chr2:169404211chr2:169707594ENST00000392687+211263_28392.0393.0TransmembraneHelical
HgeneCERS6chr2:169404211chr2:169707594ENST00000392687+211303_32392.0393.0TransmembraneHelical
TgeneNOSTRINchr2:169404211chr2:169699501ENST00000317647616160_222168.0507.0Coiled coilOntology_term=ECO:0000255
TgeneNOSTRINchr2:169404211chr2:169699501ENST00000444448819160_222168.0564.0Coiled coilOntology_term=ECO:0000255
TgeneNOSTRINchr2:169404211chr2:169699501ENST000004583811021160_222168.0564.0Coiled coilOntology_term=ECO:0000255
TgeneNOSTRINchr2:169404211chr2:169699502ENST00000317647616160_222168.0507.0Coiled coilOntology_term=ECO:0000255
TgeneNOSTRINchr2:169404211chr2:169699502ENST00000444448819160_222168.0564.0Coiled coilOntology_term=ECO:0000255
TgeneNOSTRINchr2:169404211chr2:169699502ENST000004583811021160_222168.0564.0Coiled coilOntology_term=ECO:0000255
TgeneNOSTRINchr2:169404211chr2:169707593ENST00000317647716160_222210.0507.0Coiled coilOntology_term=ECO:0000255
TgeneNOSTRINchr2:169404211chr2:169707593ENST00000397209615160_222182.0479.0Coiled coilOntology_term=ECO:0000255
TgeneNOSTRINchr2:169404211chr2:169707593ENST00000421711615160_222182.0479.0Coiled coilOntology_term=ECO:0000255
TgeneNOSTRINchr2:169404211chr2:169707593ENST000004444481019160_222267.0564.0Coiled coilOntology_term=ECO:0000255
TgeneNOSTRINchr2:169404211chr2:169707593ENST000004583811221160_222267.0564.0Coiled coilOntology_term=ECO:0000255
TgeneNOSTRINchr2:169404211chr2:169707594ENST00000317647716160_222210.0507.0Coiled coilOntology_term=ECO:0000255
TgeneNOSTRINchr2:169404211chr2:169707594ENST00000397209615160_222182.0479.0Coiled coilOntology_term=ECO:0000255
TgeneNOSTRINchr2:169404211chr2:169707594ENST00000421711615160_222182.0479.0Coiled coilOntology_term=ECO:0000255
TgeneNOSTRINchr2:169404211chr2:169707594ENST000004444481019160_222267.0564.0Coiled coilOntology_term=ECO:0000255
TgeneNOSTRINchr2:169404211chr2:169707594ENST000004583811221160_222267.0564.0Coiled coilOntology_term=ECO:0000255
TgeneNOSTRINchr2:169404211chr2:169699501ENST000003176476161_260168.0507.0DomainF-BAR
TgeneNOSTRINchr2:169404211chr2:169699501ENST000003972065151_26090.0429.0DomainF-BAR
TgeneNOSTRINchr2:169404211chr2:169699501ENST000003972095151_260140.0479.0DomainF-BAR
TgeneNOSTRINchr2:169404211chr2:169699501ENST000004217115151_260140.0479.0DomainF-BAR
TgeneNOSTRINchr2:169404211chr2:169699501ENST000004444488191_260168.0564.0DomainF-BAR
TgeneNOSTRINchr2:169404211chr2:169699501ENST000004450235151_26090.0429.0DomainF-BAR
TgeneNOSTRINchr2:169404211chr2:169699501ENST0000045838110211_260168.0564.0DomainF-BAR
TgeneNOSTRINchr2:169404211chr2:169699502ENST000003176476161_260168.0507.0DomainF-BAR
TgeneNOSTRINchr2:169404211chr2:169699502ENST000003972065151_26090.0429.0DomainF-BAR
TgeneNOSTRINchr2:169404211chr2:169699502ENST000003972095151_260140.0479.0DomainF-BAR
TgeneNOSTRINchr2:169404211chr2:169699502ENST000004217115151_260140.0479.0DomainF-BAR
TgeneNOSTRINchr2:169404211chr2:169699502ENST000004444488191_260168.0564.0DomainF-BAR
TgeneNOSTRINchr2:169404211chr2:169699502ENST000004450235151_26090.0429.0DomainF-BAR
TgeneNOSTRINchr2:169404211chr2:169699502ENST0000045838110211_260168.0564.0DomainF-BAR
TgeneNOSTRINchr2:169404211chr2:169707593ENST000003176477161_260210.0507.0DomainF-BAR
TgeneNOSTRINchr2:169404211chr2:169707593ENST000003972066151_260132.0429.0DomainF-BAR
TgeneNOSTRINchr2:169404211chr2:169707593ENST000003972096151_260182.0479.0DomainF-BAR
TgeneNOSTRINchr2:169404211chr2:169707593ENST000004217116151_260182.0479.0DomainF-BAR
TgeneNOSTRINchr2:169404211chr2:169707593ENST0000044444810191_260267.0564.0DomainF-BAR
TgeneNOSTRINchr2:169404211chr2:169707593ENST000004450236151_260132.0429.0DomainF-BAR
TgeneNOSTRINchr2:169404211chr2:169707593ENST0000045838112211_260267.0564.0DomainF-BAR
TgeneNOSTRINchr2:169404211chr2:169707594ENST000003176477161_260210.0507.0DomainF-BAR
TgeneNOSTRINchr2:169404211chr2:169707594ENST000003972066151_260132.0429.0DomainF-BAR
TgeneNOSTRINchr2:169404211chr2:169707594ENST000003972096151_260182.0479.0DomainF-BAR
TgeneNOSTRINchr2:169404211chr2:169707594ENST000004217116151_260182.0479.0DomainF-BAR
TgeneNOSTRINchr2:169404211chr2:169707594ENST0000044444810191_260267.0564.0DomainF-BAR
TgeneNOSTRINchr2:169404211chr2:169707594ENST000004450236151_260132.0429.0DomainF-BAR
TgeneNOSTRINchr2:169404211chr2:169707594ENST0000045838112211_260267.0564.0DomainF-BAR


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Fusion Protein-Protein Interaction


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type from validated records (BIOGRID-3.4.160)
GenePPI interactors


check button Protein-protein interactors based on sequence similarity (STRING)
GeneSTRING network
CERS6
NOSTRIN


check button - Retained interactions in fusion protein (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost interactions due to fusion (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs to CERS6-NOSTRIN


check button Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDrugSourcePMID

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Related Diseases to CERS6-NOSTRIN


check button Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDiseaseSourcePMID

check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource