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	Fusion Gene Summary
	Fusion Gene Sample Information
	Fusion ORF Analysis
	Fusion Amino Acid Sequences
	Fusion Protein Functional Features
	Fusion Protein-Protein Interaction
	Related drugs with this fusion protein
	Related disease with this fusion protein

Fusion Protein:CHD7-TCF7L2

Fusion Protein Summary

Fusion gene summary

Fusion partner gene information	Fusion gene name: CHD7-TCF7L2
	FusionPDB ID: 16382
	FusionGDB2.0 ID: 16382
		Hgene	Tgene
	Gene symbol	CHD7	TCF7L2
	Gene ID	55636	6934
	Gene name	chromodomain helicase DNA binding protein 7	transcription factor 7 like 2
	Synonyms	CRG\|HH5\|IS3\|KAL5	TCF-4\|TCF4
	Cytomap	8q12.2	10q25.2-q25.3
	Type of gene	protein-coding	protein-coding
	Description	chromodomain-helicase-DNA-binding protein 7ATP-dependent helicase CHD7CHARGE associationchromodomain helicase DNA binding protein 7 isoform CRA_e	transcription factor 7-like 2HMG box transcription factor 4T-cell factor 4T-cell-specific transcription factor 4hTCF-4transcription factor 7-like 2 (T-cell specific, HMG-box)
	Modification date	20200328	20200315
	UniProtAcc	Q9P2D1	Q9NQB0
Ensembl transtripts involved in fusion gene	ENST ids	ENST00000423902, ENST00000524602, ENST00000525508, ENST00000529472,	ENST00000542695, ENST00000369386, ENST00000369389, ENST00000466338, ENST00000349937, ENST00000352065, ENST00000355717, ENST00000355995, ENST00000369395, ENST00000369397, ENST00000534894, ENST00000536810, ENST00000538897, ENST00000543371, ENST00000545257,
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)	* DoF score	12 X 8 X 8=768	12 X 11 X 10=1320
	# samples	17	17
	** MAII score	log2(17/768*10)=-2.17557156458345 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(17/1320*10)=-2.95693127810811 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context (manual curation of fusion genes in FusionPDB)	PubMed: CHD7 [Title/Abstract] AND TCF7L2 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)	CHD7(61655656)-TCF7L2(114900943), # samples:3 TCF7L2(114799885)-CHD7(61693559), # samples:3
Anticipated loss of major functional domain due to fusion event.	CHD7-TCF7L2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. CHD7-TCF7L2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. CHD7-TCF7L2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. CHD7-TCF7L2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. TCF7L2-CHD7 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. TCF7L2-CHD7 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Tgene	TCF7L2	GO:0000122	negative regulation of transcription by RNA polymerase II	12799378
Tgene	TCF7L2	GO:0006357	regulation of transcription by RNA polymerase II	9727977
Tgene	TCF7L2	GO:0032092	positive regulation of protein binding	12799378
Tgene	TCF7L2	GO:0032350	regulation of hormone metabolic process	15525634
Tgene	TCF7L2	GO:0042593	glucose homeostasis	15525634
Tgene	TCF7L2	GO:0043433	negative regulation of DNA-binding transcription factor activity	12799378
Tgene	TCF7L2	GO:0045444	fat cell differentiation	10937998
Tgene	TCF7L2	GO:0045892	negative regulation of transcription, DNA-templated	12799378\|15525634
Tgene	TCF7L2	GO:0045944	positive regulation of transcription by RNA polymerase II	9065401\|19168596
Tgene	TCF7L2	GO:0048625	myoblast fate commitment	10937998

Fusion gene breakpoints across CHD7 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across TCF7L2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

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Fusion Gene Sample Information

Fusion gene information from FusionGDB2.0.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	COAD	TCGA-F4-6807-01A	CHD7	chr8	61655656	-	TCF7L2	chr10	114900943	+
ChimerDB4	COAD	TCGA-F4-6807-01A	CHD7	chr8	61655656	+	TCF7L2	chr10	114900943	+
ChimerDB4	COAD	TCGA-F4-6807	CHD7	chr8	61655656	+	TCF7L2	chr10	114900942	+

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Fusion ORF Analysis

Fusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000423902	CHD7	chr8	61655656	+	ENST00000534894	TCF7L2	chr10	114900943	+	3077	2144	446	3076	877
ENST00000423902	CHD7	chr8	61655656	+	ENST00000536810	TCF7L2	chr10	114900943	+	5107	2144	446	3400	984
ENST00000423902	CHD7	chr8	61655656	+	ENST00000545257	TCF7L2	chr10	114900943	+	5158	2144	446	3451	1001
ENST00000423902	CHD7	chr8	61655656	+	ENST00000355995	TCF7L2	chr10	114900943	+	5158	2144	446	3451	1001
ENST00000423902	CHD7	chr8	61655656	+	ENST00000543371	TCF7L2	chr10	114900943	+	5107	2144	446	3400	984
ENST00000423902	CHD7	chr8	61655656	+	ENST00000355717	TCF7L2	chr10	114900943	+	5034	2144	446	2989	847
ENST00000423902	CHD7	chr8	61655656	+	ENST00000538897	TCF7L2	chr10	114900943	+	5085	2144	446	3040	864
ENST00000423902	CHD7	chr8	61655656	+	ENST00000349937	TCF7L2	chr10	114900943	+	2461	2144	446	2458	670
ENST00000423902	CHD7	chr8	61655656	+	ENST00000369397	TCF7L2	chr10	114900943	+	5158	2144	446	3451	1001
ENST00000423902	CHD7	chr8	61655656	+	ENST00000352065	TCF7L2	chr10	114900943	+	3117	2144	446	3040	864
ENST00000423902	CHD7	chr8	61655656	+	ENST00000369395	TCF7L2	chr10	114900943	+	2473	2144	446	2470	674
ENST00000524602	CHD7	chr8	61655656	+	ENST00000534894	TCF7L2	chr10	114900943	+	2666	1733	35	2665	877
ENST00000524602	CHD7	chr8	61655656	+	ENST00000536810	TCF7L2	chr10	114900943	+	4696	1733	35	2989	984
ENST00000524602	CHD7	chr8	61655656	+	ENST00000545257	TCF7L2	chr10	114900943	+	4747	1733	35	3040	1001
ENST00000524602	CHD7	chr8	61655656	+	ENST00000355995	TCF7L2	chr10	114900943	+	4747	1733	35	3040	1001
ENST00000524602	CHD7	chr8	61655656	+	ENST00000543371	TCF7L2	chr10	114900943	+	4696	1733	35	2989	984
ENST00000524602	CHD7	chr8	61655656	+	ENST00000355717	TCF7L2	chr10	114900943	+	4623	1733	35	2578	847
ENST00000524602	CHD7	chr8	61655656	+	ENST00000538897	TCF7L2	chr10	114900943	+	4674	1733	35	2629	864
ENST00000524602	CHD7	chr8	61655656	+	ENST00000349937	TCF7L2	chr10	114900943	+	2050	1733	35	2047	670
ENST00000524602	CHD7	chr8	61655656	+	ENST00000369397	TCF7L2	chr10	114900943	+	4747	1733	35	3040	1001
ENST00000524602	CHD7	chr8	61655656	+	ENST00000352065	TCF7L2	chr10	114900943	+	2706	1733	35	2629	864
ENST00000524602	CHD7	chr8	61655656	+	ENST00000369395	TCF7L2	chr10	114900943	+	2062	1733	35	2059	674
ENST00000525508	CHD7	chr8	61655656	+	ENST00000534894	TCF7L2	chr10	114900943	+	2598	1665	0	2597	865
ENST00000525508	CHD7	chr8	61655656	+	ENST00000536810	TCF7L2	chr10	114900943	+	4628	1665	0	2921	973
ENST00000525508	CHD7	chr8	61655656	+	ENST00000545257	TCF7L2	chr10	114900943	+	4679	1665	0	2972	990
ENST00000525508	CHD7	chr8	61655656	+	ENST00000355995	TCF7L2	chr10	114900943	+	4679	1665	0	2972	990
ENST00000525508	CHD7	chr8	61655656	+	ENST00000543371	TCF7L2	chr10	114900943	+	4628	1665	0	2921	973
ENST00000525508	CHD7	chr8	61655656	+	ENST00000355717	TCF7L2	chr10	114900943	+	4555	1665	0	2510	836
ENST00000525508	CHD7	chr8	61655656	+	ENST00000538897	TCF7L2	chr10	114900943	+	4606	1665	0	2561	853
ENST00000525508	CHD7	chr8	61655656	+	ENST00000349937	TCF7L2	chr10	114900943	+	1982	1665	0	1979	659
ENST00000525508	CHD7	chr8	61655656	+	ENST00000369397	TCF7L2	chr10	114900943	+	4679	1665	0	2972	990
ENST00000525508	CHD7	chr8	61655656	+	ENST00000352065	TCF7L2	chr10	114900943	+	2638	1665	0	2561	853
ENST00000525508	CHD7	chr8	61655656	+	ENST00000369395	TCF7L2	chr10	114900943	+	1994	1665	0	1991	663
ENST00000423902	CHD7	chr8	61655656	+	ENST00000534894	TCF7L2	chr10	114900942	+	3077	2144	446	3076	877
ENST00000423902	CHD7	chr8	61655656	+	ENST00000536810	TCF7L2	chr10	114900942	+	5107	2144	446	3400	984
ENST00000423902	CHD7	chr8	61655656	+	ENST00000545257	TCF7L2	chr10	114900942	+	5158	2144	446	3451	1001
ENST00000423902	CHD7	chr8	61655656	+	ENST00000355995	TCF7L2	chr10	114900942	+	5158	2144	446	3451	1001
ENST00000423902	CHD7	chr8	61655656	+	ENST00000543371	TCF7L2	chr10	114900942	+	5107	2144	446	3400	984
ENST00000423902	CHD7	chr8	61655656	+	ENST00000355717	TCF7L2	chr10	114900942	+	5034	2144	446	2989	847
ENST00000423902	CHD7	chr8	61655656	+	ENST00000538897	TCF7L2	chr10	114900942	+	5085	2144	446	3040	864
ENST00000423902	CHD7	chr8	61655656	+	ENST00000349937	TCF7L2	chr10	114900942	+	2461	2144	446	2458	670
ENST00000423902	CHD7	chr8	61655656	+	ENST00000369397	TCF7L2	chr10	114900942	+	5158	2144	446	3451	1001
ENST00000423902	CHD7	chr8	61655656	+	ENST00000352065	TCF7L2	chr10	114900942	+	3117	2144	446	3040	864
ENST00000423902	CHD7	chr8	61655656	+	ENST00000369395	TCF7L2	chr10	114900942	+	2473	2144	446	2470	674
ENST00000524602	CHD7	chr8	61655656	+	ENST00000534894	TCF7L2	chr10	114900942	+	2666	1733	35	2665	877
ENST00000524602	CHD7	chr8	61655656	+	ENST00000536810	TCF7L2	chr10	114900942	+	4696	1733	35	2989	984
ENST00000524602	CHD7	chr8	61655656	+	ENST00000545257	TCF7L2	chr10	114900942	+	4747	1733	35	3040	1001
ENST00000524602	CHD7	chr8	61655656	+	ENST00000355995	TCF7L2	chr10	114900942	+	4747	1733	35	3040	1001
ENST00000524602	CHD7	chr8	61655656	+	ENST00000543371	TCF7L2	chr10	114900942	+	4696	1733	35	2989	984
ENST00000524602	CHD7	chr8	61655656	+	ENST00000355717	TCF7L2	chr10	114900942	+	4623	1733	35	2578	847
ENST00000524602	CHD7	chr8	61655656	+	ENST00000538897	TCF7L2	chr10	114900942	+	4674	1733	35	2629	864
ENST00000524602	CHD7	chr8	61655656	+	ENST00000349937	TCF7L2	chr10	114900942	+	2050	1733	35	2047	670
ENST00000524602	CHD7	chr8	61655656	+	ENST00000369397	TCF7L2	chr10	114900942	+	4747	1733	35	3040	1001
ENST00000524602	CHD7	chr8	61655656	+	ENST00000352065	TCF7L2	chr10	114900942	+	2706	1733	35	2629	864
ENST00000524602	CHD7	chr8	61655656	+	ENST00000369395	TCF7L2	chr10	114900942	+	2062	1733	35	2059	674
ENST00000525508	CHD7	chr8	61655656	+	ENST00000534894	TCF7L2	chr10	114900942	+	2598	1665	0	2597	865
ENST00000525508	CHD7	chr8	61655656	+	ENST00000536810	TCF7L2	chr10	114900942	+	4628	1665	0	2921	973
ENST00000525508	CHD7	chr8	61655656	+	ENST00000545257	TCF7L2	chr10	114900942	+	4679	1665	0	2972	990
ENST00000525508	CHD7	chr8	61655656	+	ENST00000355995	TCF7L2	chr10	114900942	+	4679	1665	0	2972	990
ENST00000525508	CHD7	chr8	61655656	+	ENST00000543371	TCF7L2	chr10	114900942	+	4628	1665	0	2921	973
ENST00000525508	CHD7	chr8	61655656	+	ENST00000355717	TCF7L2	chr10	114900942	+	4555	1665	0	2510	836
ENST00000525508	CHD7	chr8	61655656	+	ENST00000538897	TCF7L2	chr10	114900942	+	4606	1665	0	2561	853
ENST00000525508	CHD7	chr8	61655656	+	ENST00000349937	TCF7L2	chr10	114900942	+	1982	1665	0	1979	659
ENST00000525508	CHD7	chr8	61655656	+	ENST00000369397	TCF7L2	chr10	114900942	+	4679	1665	0	2972	990
ENST00000525508	CHD7	chr8	61655656	+	ENST00000352065	TCF7L2	chr10	114900942	+	2638	1665	0	2561	853
ENST00000525508	CHD7	chr8	61655656	+	ENST00000369395	TCF7L2	chr10	114900942	+	1994	1665	0	1991	663

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000423902	ENST00000534894	CHD7	chr8	61655656	+	TCF7L2	chr10	114900943	+	0.009496365	0.9905036
ENST00000423902	ENST00000536810	CHD7	chr8	61655656	+	TCF7L2	chr10	114900943	+	0.000871484	0.9991285
ENST00000423902	ENST00000545257	CHD7	chr8	61655656	+	TCF7L2	chr10	114900943	+	0.00095665	0.9990433
ENST00000423902	ENST00000355995	CHD7	chr8	61655656	+	TCF7L2	chr10	114900943	+	0.000979366	0.9990206
ENST00000423902	ENST00000543371	CHD7	chr8	61655656	+	TCF7L2	chr10	114900943	+	0.000876115	0.9991239
ENST00000423902	ENST00000355717	CHD7	chr8	61655656	+	TCF7L2	chr10	114900943	+	0.001232394	0.9987676
ENST00000423902	ENST00000538897	CHD7	chr8	61655656	+	TCF7L2	chr10	114900943	+	0.001151424	0.99884856
ENST00000423902	ENST00000349937	CHD7	chr8	61655656	+	TCF7L2	chr10	114900943	+	0.01804331	0.9819567
ENST00000423902	ENST00000369397	CHD7	chr8	61655656	+	TCF7L2	chr10	114900943	+	0.000979366	0.9990206
ENST00000423902	ENST00000352065	CHD7	chr8	61655656	+	TCF7L2	chr10	114900943	+	0.00996587	0.99003416
ENST00000423902	ENST00000369395	CHD7	chr8	61655656	+	TCF7L2	chr10	114900943	+	0.017641777	0.98235816
ENST00000524602	ENST00000534894	CHD7	chr8	61655656	+	TCF7L2	chr10	114900943	+	0.009550003	0.99044997
ENST00000524602	ENST00000536810	CHD7	chr8	61655656	+	TCF7L2	chr10	114900943	+	0.000572046	0.999428
ENST00000524602	ENST00000545257	CHD7	chr8	61655656	+	TCF7L2	chr10	114900943	+	0.000529873	0.9994702
ENST00000524602	ENST00000355995	CHD7	chr8	61655656	+	TCF7L2	chr10	114900943	+	0.000538633	0.99946135
ENST00000524602	ENST00000543371	CHD7	chr8	61655656	+	TCF7L2	chr10	114900943	+	0.000578963	0.999421
ENST00000524602	ENST00000355717	CHD7	chr8	61655656	+	TCF7L2	chr10	114900943	+	0.001091078	0.9989089
ENST00000524602	ENST00000538897	CHD7	chr8	61655656	+	TCF7L2	chr10	114900943	+	0.001015115	0.9989849
ENST00000524602	ENST00000349937	CHD7	chr8	61655656	+	TCF7L2	chr10	114900943	+	0.014109334	0.9858906
ENST00000524602	ENST00000369397	CHD7	chr8	61655656	+	TCF7L2	chr10	114900943	+	0.000538633	0.99946135
ENST00000524602	ENST00000352065	CHD7	chr8	61655656	+	TCF7L2	chr10	114900943	+	0.01004532	0.9899547
ENST00000524602	ENST00000369395	CHD7	chr8	61655656	+	TCF7L2	chr10	114900943	+	0.013914617	0.9860854
ENST00000525508	ENST00000534894	CHD7	chr8	61655656	+	TCF7L2	chr10	114900943	+	0.009009481	0.9909905
ENST00000525508	ENST00000536810	CHD7	chr8	61655656	+	TCF7L2	chr10	114900943	+	0.000543431	0.9994566
ENST00000525508	ENST00000545257	CHD7	chr8	61655656	+	TCF7L2	chr10	114900943	+	0.000502327	0.99949765
ENST00000525508	ENST00000355995	CHD7	chr8	61655656	+	TCF7L2	chr10	114900943	+	0.000510328	0.99948967
ENST00000525508	ENST00000543371	CHD7	chr8	61655656	+	TCF7L2	chr10	114900943	+	0.000549608	0.9994504
ENST00000525508	ENST00000355717	CHD7	chr8	61655656	+	TCF7L2	chr10	114900943	+	0.00103337	0.9989667
ENST00000525508	ENST00000538897	CHD7	chr8	61655656	+	TCF7L2	chr10	114900943	+	0.000960464	0.9990395
ENST00000525508	ENST00000349937	CHD7	chr8	61655656	+	TCF7L2	chr10	114900943	+	0.012863197	0.98713684
ENST00000525508	ENST00000369397	CHD7	chr8	61655656	+	TCF7L2	chr10	114900943	+	0.000510328	0.99948967
ENST00000525508	ENST00000352065	CHD7	chr8	61655656	+	TCF7L2	chr10	114900943	+	0.009510737	0.99048924
ENST00000525508	ENST00000369395	CHD7	chr8	61655656	+	TCF7L2	chr10	114900943	+	0.012728255	0.9872717
ENST00000423902	ENST00000534894	CHD7	chr8	61655656	+	TCF7L2	chr10	114900942	+	0.009496365	0.9905036
ENST00000423902	ENST00000536810	CHD7	chr8	61655656	+	TCF7L2	chr10	114900942	+	0.000871484	0.9991285
ENST00000423902	ENST00000545257	CHD7	chr8	61655656	+	TCF7L2	chr10	114900942	+	0.00095665	0.9990433
ENST00000423902	ENST00000355995	CHD7	chr8	61655656	+	TCF7L2	chr10	114900942	+	0.000979366	0.9990206
ENST00000423902	ENST00000543371	CHD7	chr8	61655656	+	TCF7L2	chr10	114900942	+	0.000876115	0.9991239
ENST00000423902	ENST00000355717	CHD7	chr8	61655656	+	TCF7L2	chr10	114900942	+	0.001232394	0.9987676
ENST00000423902	ENST00000538897	CHD7	chr8	61655656	+	TCF7L2	chr10	114900942	+	0.001151424	0.99884856
ENST00000423902	ENST00000349937	CHD7	chr8	61655656	+	TCF7L2	chr10	114900942	+	0.01804331	0.9819567
ENST00000423902	ENST00000369397	CHD7	chr8	61655656	+	TCF7L2	chr10	114900942	+	0.000979366	0.9990206
ENST00000423902	ENST00000352065	CHD7	chr8	61655656	+	TCF7L2	chr10	114900942	+	0.00996587	0.99003416
ENST00000423902	ENST00000369395	CHD7	chr8	61655656	+	TCF7L2	chr10	114900942	+	0.017641777	0.98235816
ENST00000524602	ENST00000534894	CHD7	chr8	61655656	+	TCF7L2	chr10	114900942	+	0.009550003	0.99044997
ENST00000524602	ENST00000536810	CHD7	chr8	61655656	+	TCF7L2	chr10	114900942	+	0.000572046	0.999428
ENST00000524602	ENST00000545257	CHD7	chr8	61655656	+	TCF7L2	chr10	114900942	+	0.000529873	0.9994702
ENST00000524602	ENST00000355995	CHD7	chr8	61655656	+	TCF7L2	chr10	114900942	+	0.000538633	0.99946135
ENST00000524602	ENST00000543371	CHD7	chr8	61655656	+	TCF7L2	chr10	114900942	+	0.000578963	0.999421
ENST00000524602	ENST00000355717	CHD7	chr8	61655656	+	TCF7L2	chr10	114900942	+	0.001091078	0.9989089
ENST00000524602	ENST00000538897	CHD7	chr8	61655656	+	TCF7L2	chr10	114900942	+	0.001015115	0.9989849
ENST00000524602	ENST00000349937	CHD7	chr8	61655656	+	TCF7L2	chr10	114900942	+	0.014109334	0.9858906
ENST00000524602	ENST00000369397	CHD7	chr8	61655656	+	TCF7L2	chr10	114900942	+	0.000538633	0.99946135
ENST00000524602	ENST00000352065	CHD7	chr8	61655656	+	TCF7L2	chr10	114900942	+	0.01004532	0.9899547
ENST00000524602	ENST00000369395	CHD7	chr8	61655656	+	TCF7L2	chr10	114900942	+	0.013914617	0.9860854
ENST00000525508	ENST00000534894	CHD7	chr8	61655656	+	TCF7L2	chr10	114900942	+	0.009009481	0.9909905
ENST00000525508	ENST00000536810	CHD7	chr8	61655656	+	TCF7L2	chr10	114900942	+	0.000543431	0.9994566
ENST00000525508	ENST00000545257	CHD7	chr8	61655656	+	TCF7L2	chr10	114900942	+	0.000502327	0.99949765
ENST00000525508	ENST00000355995	CHD7	chr8	61655656	+	TCF7L2	chr10	114900942	+	0.000510328	0.99948967
ENST00000525508	ENST00000543371	CHD7	chr8	61655656	+	TCF7L2	chr10	114900942	+	0.000549608	0.9994504
ENST00000525508	ENST00000355717	CHD7	chr8	61655656	+	TCF7L2	chr10	114900942	+	0.00103337	0.9989667
ENST00000525508	ENST00000538897	CHD7	chr8	61655656	+	TCF7L2	chr10	114900942	+	0.000960464	0.9990395
ENST00000525508	ENST00000349937	CHD7	chr8	61655656	+	TCF7L2	chr10	114900942	+	0.012863197	0.98713684
ENST00000525508	ENST00000369397	CHD7	chr8	61655656	+	TCF7L2	chr10	114900942	+	0.000510328	0.99948967
ENST00000525508	ENST00000352065	CHD7	chr8	61655656	+	TCF7L2	chr10	114900942	+	0.009510737	0.99048924
ENST00000525508	ENST00000369395	CHD7	chr8	61655656	+	TCF7L2	chr10	114900942	+	0.012728255	0.9872717

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Fusion Amino Acid Sequences

For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

>16382_16382_1_CHD7-TCF7L2_CHD7_chr8_61655656_ENST00000423902_TCF7L2_chr10_114900942_ENST00000349937_length(amino acids)=670AA_BP=565
MWFGGAVCWKKMADPGMMSLFGEDGNIFSEGLEGLGECGYPENPVNPMGQQMPIDQGFASLQPSLHHPSTNQNQTKLTHFDHYNQYEQQK
MHLMDQPNRMMSNTPGNGLASPHSQYHTPPVPQVPHGGSGGGQMGVYPGMQNERHGQSFVDSSSMWGPRAVQVPDQIRAPYQQQQPQPQP
PQPAPSGPPAQGHPQHMQQMGSYMARGDFSMQQHGQPQQRMSQFSQGQEGLNQGNPFIATSGPGHLSHVPQQSPSMAPSLRHSVQQFHHH
PSTALHGESVAHSPRFSPNPPQQGAVRPQTLNFSSRSQTVPSPTINNSGQYSRYPYSNLNQGLVNNTGMNQNLGLTNNTPMNQSVPRYPN
AVGFPSNSGQGLMHQQPIHPSGSLNQMNTQTMHPSQPQGTYASPPPMSPMKAMSNPAGTPPPQVRPGSAGIPMEVGSYPNMPHPQPSHQP
PGAMGIGQRNMGPRNMQQSRPFIGMSSAPRELTGHMRPNGCPGVGLGDPQAIQERLIPGQQHPGQQPSFQQLPTCPPLQPHPGLHHQSSP
PHPHHQPWAQLHPSPQNTPQKVPVHQSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPG

--------------------------------------------------------------

>16382_16382_2_CHD7-TCF7L2_CHD7_chr8_61655656_ENST00000423902_TCF7L2_chr10_114900942_ENST00000352065_length(amino acids)=864AA_BP=565
MWFGGAVCWKKMADPGMMSLFGEDGNIFSEGLEGLGECGYPENPVNPMGQQMPIDQGFASLQPSLHHPSTNQNQTKLTHFDHYNQYEQQK
MHLMDQPNRMMSNTPGNGLASPHSQYHTPPVPQVPHGGSGGGQMGVYPGMQNERHGQSFVDSSSMWGPRAVQVPDQIRAPYQQQQPQPQP
PQPAPSGPPAQGHPQHMQQMGSYMARGDFSMQQHGQPQQRMSQFSQGQEGLNQGNPFIATSGPGHLSHVPQQSPSMAPSLRHSVQQFHHH
PSTALHGESVAHSPRFSPNPPQQGAVRPQTLNFSSRSQTVPSPTINNSGQYSRYPYSNLNQGLVNNTGMNQNLGLTNNTPMNQSVPRYPN
AVGFPSNSGQGLMHQQPIHPSGSLNQMNTQTMHPSQPQGTYASPPPMSPMKAMSNPAGTPPPQVRPGSAGIPMEVGSYPNMPHPQPSHQP
PGAMGIGQRNMGPRNMQQSRPFIGMSSAPRELTGHMRPNGCPGVGLGDPQAIQERLIPGQQHPGQQPSFQQLPTCPPLQPHPGLHHQSSP
PHPHHQPWAQLHPSPQNTPQKVPVHQSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPG
TVGQIPHPLGWLVPQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQD
SKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKK

--------------------------------------------------------------

>16382_16382_3_CHD7-TCF7L2_CHD7_chr8_61655656_ENST00000423902_TCF7L2_chr10_114900942_ENST00000355717_length(amino acids)=847AA_BP=565
MWFGGAVCWKKMADPGMMSLFGEDGNIFSEGLEGLGECGYPENPVNPMGQQMPIDQGFASLQPSLHHPSTNQNQTKLTHFDHYNQYEQQK
MHLMDQPNRMMSNTPGNGLASPHSQYHTPPVPQVPHGGSGGGQMGVYPGMQNERHGQSFVDSSSMWGPRAVQVPDQIRAPYQQQQPQPQP
PQPAPSGPPAQGHPQHMQQMGSYMARGDFSMQQHGQPQQRMSQFSQGQEGLNQGNPFIATSGPGHLSHVPQQSPSMAPSLRHSVQQFHHH
PSTALHGESVAHSPRFSPNPPQQGAVRPQTLNFSSRSQTVPSPTINNSGQYSRYPYSNLNQGLVNNTGMNQNLGLTNNTPMNQSVPRYPN
AVGFPSNSGQGLMHQQPIHPSGSLNQMNTQTMHPSQPQGTYASPPPMSPMKAMSNPAGTPPPQVRPGSAGIPMEVGSYPNMPHPQPSHQP
PGAMGIGQRNMGPRNMQQSRPFIGMSSAPRELTGHMRPNGCPGVGLGDPQAIQERLIPGQQHPGQQPSFQQLPTCPPLQPHPGLHHQSSP
PHPHHQPWAQLHPSPQNTPQKVPVHQSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPG
TVGQIPHPLGWLVPQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQD
SKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKK

--------------------------------------------------------------

>16382_16382_4_CHD7-TCF7L2_CHD7_chr8_61655656_ENST00000423902_TCF7L2_chr10_114900942_ENST00000355995_length(amino acids)=1001AA_BP=565
MWFGGAVCWKKMADPGMMSLFGEDGNIFSEGLEGLGECGYPENPVNPMGQQMPIDQGFASLQPSLHHPSTNQNQTKLTHFDHYNQYEQQK
MHLMDQPNRMMSNTPGNGLASPHSQYHTPPVPQVPHGGSGGGQMGVYPGMQNERHGQSFVDSSSMWGPRAVQVPDQIRAPYQQQQPQPQP
PQPAPSGPPAQGHPQHMQQMGSYMARGDFSMQQHGQPQQRMSQFSQGQEGLNQGNPFIATSGPGHLSHVPQQSPSMAPSLRHSVQQFHHH
PSTALHGESVAHSPRFSPNPPQQGAVRPQTLNFSSRSQTVPSPTINNSGQYSRYPYSNLNQGLVNNTGMNQNLGLTNNTPMNQSVPRYPN
AVGFPSNSGQGLMHQQPIHPSGSLNQMNTQTMHPSQPQGTYASPPPMSPMKAMSNPAGTPPPQVRPGSAGIPMEVGSYPNMPHPQPSHQP
PGAMGIGQRNMGPRNMQQSRPFIGMSSAPRELTGHMRPNGCPGVGLGDPQAIQERLIPGQQHPGQQPSFQQLPTCPPLQPHPGLHHQSSP
PHPHHQPWAQLHPSPQNTPQKVPVHQSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPG
TVGQIPHPLGWLVPQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQD
SKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKK
RKRDKQPGETNEHSECFLNPCLSLPPITDLSAPKKCRARFGLDQQNNWCGPCRRKKKCVRYIQGEGSCLSPPSSDGSLLDSPPPSPNLLG
SPPRDAKSQTEQTQPLSLSLKPDPLAHLSMMPPPPALLLAEATHKASALCPNGALDLPPAALQPAAPSSSIAQPSTSSLHSHSSLAGTQP

--------------------------------------------------------------

>16382_16382_5_CHD7-TCF7L2_CHD7_chr8_61655656_ENST00000423902_TCF7L2_chr10_114900942_ENST00000369395_length(amino acids)=674AA_BP=565
MWFGGAVCWKKMADPGMMSLFGEDGNIFSEGLEGLGECGYPENPVNPMGQQMPIDQGFASLQPSLHHPSTNQNQTKLTHFDHYNQYEQQK
MHLMDQPNRMMSNTPGNGLASPHSQYHTPPVPQVPHGGSGGGQMGVYPGMQNERHGQSFVDSSSMWGPRAVQVPDQIRAPYQQQQPQPQP
PQPAPSGPPAQGHPQHMQQMGSYMARGDFSMQQHGQPQQRMSQFSQGQEGLNQGNPFIATSGPGHLSHVPQQSPSMAPSLRHSVQQFHHH
PSTALHGESVAHSPRFSPNPPQQGAVRPQTLNFSSRSQTVPSPTINNSGQYSRYPYSNLNQGLVNNTGMNQNLGLTNNTPMNQSVPRYPN
AVGFPSNSGQGLMHQQPIHPSGSLNQMNTQTMHPSQPQGTYASPPPMSPMKAMSNPAGTPPPQVRPGSAGIPMEVGSYPNMPHPQPSHQP
PGAMGIGQRNMGPRNMQQSRPFIGMSSAPRELTGHMRPNGCPGVGLGDPQAIQERLIPGQQHPGQQPSFQQLPTCPPLQPHPGLHHQSSP
PHPHHQPWAQLHPSPQNTPQKVPVHQSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPG

--------------------------------------------------------------

>16382_16382_6_CHD7-TCF7L2_CHD7_chr8_61655656_ENST00000423902_TCF7L2_chr10_114900942_ENST00000369397_length(amino acids)=1001AA_BP=565
MWFGGAVCWKKMADPGMMSLFGEDGNIFSEGLEGLGECGYPENPVNPMGQQMPIDQGFASLQPSLHHPSTNQNQTKLTHFDHYNQYEQQK
MHLMDQPNRMMSNTPGNGLASPHSQYHTPPVPQVPHGGSGGGQMGVYPGMQNERHGQSFVDSSSMWGPRAVQVPDQIRAPYQQQQPQPQP
PQPAPSGPPAQGHPQHMQQMGSYMARGDFSMQQHGQPQQRMSQFSQGQEGLNQGNPFIATSGPGHLSHVPQQSPSMAPSLRHSVQQFHHH
PSTALHGESVAHSPRFSPNPPQQGAVRPQTLNFSSRSQTVPSPTINNSGQYSRYPYSNLNQGLVNNTGMNQNLGLTNNTPMNQSVPRYPN
AVGFPSNSGQGLMHQQPIHPSGSLNQMNTQTMHPSQPQGTYASPPPMSPMKAMSNPAGTPPPQVRPGSAGIPMEVGSYPNMPHPQPSHQP
PGAMGIGQRNMGPRNMQQSRPFIGMSSAPRELTGHMRPNGCPGVGLGDPQAIQERLIPGQQHPGQQPSFQQLPTCPPLQPHPGLHHQSSP
PHPHHQPWAQLHPSPQNTPQKVPVHQSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPG
TVGQIPHPLGWLVPQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQD
SKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKK
RKRDKQPGETNEHSECFLNPCLSLPPITDLSAPKKCRARFGLDQQNNWCGPCRRKKKCVRYIQGEGSCLSPPSSDGSLLDSPPPSPNLLG
SPPRDAKSQTEQTQPLSLSLKPDPLAHLSMMPPPPALLLAEATHKASALCPNGALDLPPAALQPAAPSSSIAQPSTSSLHSHSSLAGTQP

--------------------------------------------------------------

>16382_16382_7_CHD7-TCF7L2_CHD7_chr8_61655656_ENST00000423902_TCF7L2_chr10_114900942_ENST00000534894_length(amino acids)=877AA_BP=565
MWFGGAVCWKKMADPGMMSLFGEDGNIFSEGLEGLGECGYPENPVNPMGQQMPIDQGFASLQPSLHHPSTNQNQTKLTHFDHYNQYEQQK
MHLMDQPNRMMSNTPGNGLASPHSQYHTPPVPQVPHGGSGGGQMGVYPGMQNERHGQSFVDSSSMWGPRAVQVPDQIRAPYQQQQPQPQP
PQPAPSGPPAQGHPQHMQQMGSYMARGDFSMQQHGQPQQRMSQFSQGQEGLNQGNPFIATSGPGHLSHVPQQSPSMAPSLRHSVQQFHHH
PSTALHGESVAHSPRFSPNPPQQGAVRPQTLNFSSRSQTVPSPTINNSGQYSRYPYSNLNQGLVNNTGMNQNLGLTNNTPMNQSVPRYPN
AVGFPSNSGQGLMHQQPIHPSGSLNQMNTQTMHPSQPQGTYASPPPMSPMKAMSNPAGTPPPQVRPGSAGIPMEVGSYPNMPHPQPSHQP
PGAMGIGQRNMGPRNMQQSRPFIGMSSAPRELTGHMRPNGCPGVGLGDPQAIQERLIPGQQHPGQQPSFQQLPTCPPLQPHPGLHHQSSP
PHPHHQPWAQLHPSPQNTPQKVPVHQSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPG
TVGQIPHPLGWLVPQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQD
SKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKK

--------------------------------------------------------------

>16382_16382_8_CHD7-TCF7L2_CHD7_chr8_61655656_ENST00000423902_TCF7L2_chr10_114900942_ENST00000536810_length(amino acids)=984AA_BP=565
MWFGGAVCWKKMADPGMMSLFGEDGNIFSEGLEGLGECGYPENPVNPMGQQMPIDQGFASLQPSLHHPSTNQNQTKLTHFDHYNQYEQQK
MHLMDQPNRMMSNTPGNGLASPHSQYHTPPVPQVPHGGSGGGQMGVYPGMQNERHGQSFVDSSSMWGPRAVQVPDQIRAPYQQQQPQPQP
PQPAPSGPPAQGHPQHMQQMGSYMARGDFSMQQHGQPQQRMSQFSQGQEGLNQGNPFIATSGPGHLSHVPQQSPSMAPSLRHSVQQFHHH
PSTALHGESVAHSPRFSPNPPQQGAVRPQTLNFSSRSQTVPSPTINNSGQYSRYPYSNLNQGLVNNTGMNQNLGLTNNTPMNQSVPRYPN
AVGFPSNSGQGLMHQQPIHPSGSLNQMNTQTMHPSQPQGTYASPPPMSPMKAMSNPAGTPPPQVRPGSAGIPMEVGSYPNMPHPQPSHQP
PGAMGIGQRNMGPRNMQQSRPFIGMSSAPRELTGHMRPNGCPGVGLGDPQAIQERLIPGQQHPGQQPSFQQLPTCPPLQPHPGLHHQSSP
PHPHHQPWAQLHPSPQNTPQKVPVHQSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPG
TVGQIPHPLGWLVPQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQD
SKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKK
RKRDKQPGETNDLSAPKKCRARFGLDQQNNWCGPCRRKKKCVRYIQGEGSCLSPPSSDGSLLDSPPPSPNLLGSPPRDAKSQTEQTQPLS

--------------------------------------------------------------

>16382_16382_9_CHD7-TCF7L2_CHD7_chr8_61655656_ENST00000423902_TCF7L2_chr10_114900942_ENST00000538897_length(amino acids)=864AA_BP=565
MWFGGAVCWKKMADPGMMSLFGEDGNIFSEGLEGLGECGYPENPVNPMGQQMPIDQGFASLQPSLHHPSTNQNQTKLTHFDHYNQYEQQK
MHLMDQPNRMMSNTPGNGLASPHSQYHTPPVPQVPHGGSGGGQMGVYPGMQNERHGQSFVDSSSMWGPRAVQVPDQIRAPYQQQQPQPQP
PQPAPSGPPAQGHPQHMQQMGSYMARGDFSMQQHGQPQQRMSQFSQGQEGLNQGNPFIATSGPGHLSHVPQQSPSMAPSLRHSVQQFHHH
PSTALHGESVAHSPRFSPNPPQQGAVRPQTLNFSSRSQTVPSPTINNSGQYSRYPYSNLNQGLVNNTGMNQNLGLTNNTPMNQSVPRYPN
AVGFPSNSGQGLMHQQPIHPSGSLNQMNTQTMHPSQPQGTYASPPPMSPMKAMSNPAGTPPPQVRPGSAGIPMEVGSYPNMPHPQPSHQP
PGAMGIGQRNMGPRNMQQSRPFIGMSSAPRELTGHMRPNGCPGVGLGDPQAIQERLIPGQQHPGQQPSFQQLPTCPPLQPHPGLHHQSSP
PHPHHQPWAQLHPSPQNTPQKVPVHQSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPG
TVGQIPHPLGWLVPQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQD
SKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKK

--------------------------------------------------------------

>16382_16382_10_CHD7-TCF7L2_CHD7_chr8_61655656_ENST00000423902_TCF7L2_chr10_114900942_ENST00000543371_length(amino acids)=984AA_BP=565
MWFGGAVCWKKMADPGMMSLFGEDGNIFSEGLEGLGECGYPENPVNPMGQQMPIDQGFASLQPSLHHPSTNQNQTKLTHFDHYNQYEQQK
MHLMDQPNRMMSNTPGNGLASPHSQYHTPPVPQVPHGGSGGGQMGVYPGMQNERHGQSFVDSSSMWGPRAVQVPDQIRAPYQQQQPQPQP
PQPAPSGPPAQGHPQHMQQMGSYMARGDFSMQQHGQPQQRMSQFSQGQEGLNQGNPFIATSGPGHLSHVPQQSPSMAPSLRHSVQQFHHH
PSTALHGESVAHSPRFSPNPPQQGAVRPQTLNFSSRSQTVPSPTINNSGQYSRYPYSNLNQGLVNNTGMNQNLGLTNNTPMNQSVPRYPN
AVGFPSNSGQGLMHQQPIHPSGSLNQMNTQTMHPSQPQGTYASPPPMSPMKAMSNPAGTPPPQVRPGSAGIPMEVGSYPNMPHPQPSHQP
PGAMGIGQRNMGPRNMQQSRPFIGMSSAPRELTGHMRPNGCPGVGLGDPQAIQERLIPGQQHPGQQPSFQQLPTCPPLQPHPGLHHQSSP
PHPHHQPWAQLHPSPQNTPQKVPVHQSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPG
TVGQIPHPLGWLVPQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQD
SKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKK
RKRDKQPGETNDANTPKKCRALFGLDRQTLWCKPCRRKKKCVRYIQGEGSCLSPPSSDGSLLDSPPPSPNLLGSPPRDAKSQTEQTQPLS

--------------------------------------------------------------

>16382_16382_11_CHD7-TCF7L2_CHD7_chr8_61655656_ENST00000423902_TCF7L2_chr10_114900942_ENST00000545257_length(amino acids)=1001AA_BP=565
MWFGGAVCWKKMADPGMMSLFGEDGNIFSEGLEGLGECGYPENPVNPMGQQMPIDQGFASLQPSLHHPSTNQNQTKLTHFDHYNQYEQQK
MHLMDQPNRMMSNTPGNGLASPHSQYHTPPVPQVPHGGSGGGQMGVYPGMQNERHGQSFVDSSSMWGPRAVQVPDQIRAPYQQQQPQPQP
PQPAPSGPPAQGHPQHMQQMGSYMARGDFSMQQHGQPQQRMSQFSQGQEGLNQGNPFIATSGPGHLSHVPQQSPSMAPSLRHSVQQFHHH
PSTALHGESVAHSPRFSPNPPQQGAVRPQTLNFSSRSQTVPSPTINNSGQYSRYPYSNLNQGLVNNTGMNQNLGLTNNTPMNQSVPRYPN
AVGFPSNSGQGLMHQQPIHPSGSLNQMNTQTMHPSQPQGTYASPPPMSPMKAMSNPAGTPPPQVRPGSAGIPMEVGSYPNMPHPQPSHQP
PGAMGIGQRNMGPRNMQQSRPFIGMSSAPRELTGHMRPNGCPGVGLGDPQAIQERLIPGQQHPGQQPSFQQLPTCPPLQPHPGLHHQSSP
PHPHHQPWAQLHPSPQNTPQKVPVHQSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPG
TVGQIPHPLGWLVPQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQD
SKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKK
RKRDKQPGETNEHSECFLNPCLSLPPITDANTPKKCRALFGLDRQTLWCKPCRRKKKCVRYIQGEGSCLSPPSSDGSLLDSPPPSPNLLG
SPPRDAKSQTEQTQPLSLSLKPDPLAHLSMMPPPPALLLAEATHKASALCPNGALDLPPAALQPAAPSSSIAQPSTSSLHSHSSLAGTQP

--------------------------------------------------------------

>16382_16382_12_CHD7-TCF7L2_CHD7_chr8_61655656_ENST00000423902_TCF7L2_chr10_114900943_ENST00000349937_length(amino acids)=670AA_BP=565
MWFGGAVCWKKMADPGMMSLFGEDGNIFSEGLEGLGECGYPENPVNPMGQQMPIDQGFASLQPSLHHPSTNQNQTKLTHFDHYNQYEQQK
MHLMDQPNRMMSNTPGNGLASPHSQYHTPPVPQVPHGGSGGGQMGVYPGMQNERHGQSFVDSSSMWGPRAVQVPDQIRAPYQQQQPQPQP
PQPAPSGPPAQGHPQHMQQMGSYMARGDFSMQQHGQPQQRMSQFSQGQEGLNQGNPFIATSGPGHLSHVPQQSPSMAPSLRHSVQQFHHH
PSTALHGESVAHSPRFSPNPPQQGAVRPQTLNFSSRSQTVPSPTINNSGQYSRYPYSNLNQGLVNNTGMNQNLGLTNNTPMNQSVPRYPN
AVGFPSNSGQGLMHQQPIHPSGSLNQMNTQTMHPSQPQGTYASPPPMSPMKAMSNPAGTPPPQVRPGSAGIPMEVGSYPNMPHPQPSHQP
PGAMGIGQRNMGPRNMQQSRPFIGMSSAPRELTGHMRPNGCPGVGLGDPQAIQERLIPGQQHPGQQPSFQQLPTCPPLQPHPGLHHQSSP
PHPHHQPWAQLHPSPQNTPQKVPVHQSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPG

--------------------------------------------------------------

>16382_16382_13_CHD7-TCF7L2_CHD7_chr8_61655656_ENST00000423902_TCF7L2_chr10_114900943_ENST00000352065_length(amino acids)=864AA_BP=565
MWFGGAVCWKKMADPGMMSLFGEDGNIFSEGLEGLGECGYPENPVNPMGQQMPIDQGFASLQPSLHHPSTNQNQTKLTHFDHYNQYEQQK
MHLMDQPNRMMSNTPGNGLASPHSQYHTPPVPQVPHGGSGGGQMGVYPGMQNERHGQSFVDSSSMWGPRAVQVPDQIRAPYQQQQPQPQP
PQPAPSGPPAQGHPQHMQQMGSYMARGDFSMQQHGQPQQRMSQFSQGQEGLNQGNPFIATSGPGHLSHVPQQSPSMAPSLRHSVQQFHHH
PSTALHGESVAHSPRFSPNPPQQGAVRPQTLNFSSRSQTVPSPTINNSGQYSRYPYSNLNQGLVNNTGMNQNLGLTNNTPMNQSVPRYPN
AVGFPSNSGQGLMHQQPIHPSGSLNQMNTQTMHPSQPQGTYASPPPMSPMKAMSNPAGTPPPQVRPGSAGIPMEVGSYPNMPHPQPSHQP
PGAMGIGQRNMGPRNMQQSRPFIGMSSAPRELTGHMRPNGCPGVGLGDPQAIQERLIPGQQHPGQQPSFQQLPTCPPLQPHPGLHHQSSP
PHPHHQPWAQLHPSPQNTPQKVPVHQSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPG
TVGQIPHPLGWLVPQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQD
SKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKK

--------------------------------------------------------------

>16382_16382_14_CHD7-TCF7L2_CHD7_chr8_61655656_ENST00000423902_TCF7L2_chr10_114900943_ENST00000355717_length(amino acids)=847AA_BP=565
MWFGGAVCWKKMADPGMMSLFGEDGNIFSEGLEGLGECGYPENPVNPMGQQMPIDQGFASLQPSLHHPSTNQNQTKLTHFDHYNQYEQQK
MHLMDQPNRMMSNTPGNGLASPHSQYHTPPVPQVPHGGSGGGQMGVYPGMQNERHGQSFVDSSSMWGPRAVQVPDQIRAPYQQQQPQPQP
PQPAPSGPPAQGHPQHMQQMGSYMARGDFSMQQHGQPQQRMSQFSQGQEGLNQGNPFIATSGPGHLSHVPQQSPSMAPSLRHSVQQFHHH
PSTALHGESVAHSPRFSPNPPQQGAVRPQTLNFSSRSQTVPSPTINNSGQYSRYPYSNLNQGLVNNTGMNQNLGLTNNTPMNQSVPRYPN
AVGFPSNSGQGLMHQQPIHPSGSLNQMNTQTMHPSQPQGTYASPPPMSPMKAMSNPAGTPPPQVRPGSAGIPMEVGSYPNMPHPQPSHQP
PGAMGIGQRNMGPRNMQQSRPFIGMSSAPRELTGHMRPNGCPGVGLGDPQAIQERLIPGQQHPGQQPSFQQLPTCPPLQPHPGLHHQSSP
PHPHHQPWAQLHPSPQNTPQKVPVHQSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPG
TVGQIPHPLGWLVPQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQD
SKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKK

--------------------------------------------------------------

>16382_16382_15_CHD7-TCF7L2_CHD7_chr8_61655656_ENST00000423902_TCF7L2_chr10_114900943_ENST00000355995_length(amino acids)=1001AA_BP=565
MWFGGAVCWKKMADPGMMSLFGEDGNIFSEGLEGLGECGYPENPVNPMGQQMPIDQGFASLQPSLHHPSTNQNQTKLTHFDHYNQYEQQK
MHLMDQPNRMMSNTPGNGLASPHSQYHTPPVPQVPHGGSGGGQMGVYPGMQNERHGQSFVDSSSMWGPRAVQVPDQIRAPYQQQQPQPQP
PQPAPSGPPAQGHPQHMQQMGSYMARGDFSMQQHGQPQQRMSQFSQGQEGLNQGNPFIATSGPGHLSHVPQQSPSMAPSLRHSVQQFHHH
PSTALHGESVAHSPRFSPNPPQQGAVRPQTLNFSSRSQTVPSPTINNSGQYSRYPYSNLNQGLVNNTGMNQNLGLTNNTPMNQSVPRYPN
AVGFPSNSGQGLMHQQPIHPSGSLNQMNTQTMHPSQPQGTYASPPPMSPMKAMSNPAGTPPPQVRPGSAGIPMEVGSYPNMPHPQPSHQP
PGAMGIGQRNMGPRNMQQSRPFIGMSSAPRELTGHMRPNGCPGVGLGDPQAIQERLIPGQQHPGQQPSFQQLPTCPPLQPHPGLHHQSSP
PHPHHQPWAQLHPSPQNTPQKVPVHQSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPG
TVGQIPHPLGWLVPQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQD
SKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKK
RKRDKQPGETNEHSECFLNPCLSLPPITDLSAPKKCRARFGLDQQNNWCGPCRRKKKCVRYIQGEGSCLSPPSSDGSLLDSPPPSPNLLG
SPPRDAKSQTEQTQPLSLSLKPDPLAHLSMMPPPPALLLAEATHKASALCPNGALDLPPAALQPAAPSSSIAQPSTSSLHSHSSLAGTQP

--------------------------------------------------------------

>16382_16382_16_CHD7-TCF7L2_CHD7_chr8_61655656_ENST00000423902_TCF7L2_chr10_114900943_ENST00000369395_length(amino acids)=674AA_BP=565
MWFGGAVCWKKMADPGMMSLFGEDGNIFSEGLEGLGECGYPENPVNPMGQQMPIDQGFASLQPSLHHPSTNQNQTKLTHFDHYNQYEQQK
MHLMDQPNRMMSNTPGNGLASPHSQYHTPPVPQVPHGGSGGGQMGVYPGMQNERHGQSFVDSSSMWGPRAVQVPDQIRAPYQQQQPQPQP
PQPAPSGPPAQGHPQHMQQMGSYMARGDFSMQQHGQPQQRMSQFSQGQEGLNQGNPFIATSGPGHLSHVPQQSPSMAPSLRHSVQQFHHH
PSTALHGESVAHSPRFSPNPPQQGAVRPQTLNFSSRSQTVPSPTINNSGQYSRYPYSNLNQGLVNNTGMNQNLGLTNNTPMNQSVPRYPN
AVGFPSNSGQGLMHQQPIHPSGSLNQMNTQTMHPSQPQGTYASPPPMSPMKAMSNPAGTPPPQVRPGSAGIPMEVGSYPNMPHPQPSHQP
PGAMGIGQRNMGPRNMQQSRPFIGMSSAPRELTGHMRPNGCPGVGLGDPQAIQERLIPGQQHPGQQPSFQQLPTCPPLQPHPGLHHQSSP
PHPHHQPWAQLHPSPQNTPQKVPVHQSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPG

--------------------------------------------------------------

>16382_16382_17_CHD7-TCF7L2_CHD7_chr8_61655656_ENST00000423902_TCF7L2_chr10_114900943_ENST00000369397_length(amino acids)=1001AA_BP=565
MWFGGAVCWKKMADPGMMSLFGEDGNIFSEGLEGLGECGYPENPVNPMGQQMPIDQGFASLQPSLHHPSTNQNQTKLTHFDHYNQYEQQK
MHLMDQPNRMMSNTPGNGLASPHSQYHTPPVPQVPHGGSGGGQMGVYPGMQNERHGQSFVDSSSMWGPRAVQVPDQIRAPYQQQQPQPQP
PQPAPSGPPAQGHPQHMQQMGSYMARGDFSMQQHGQPQQRMSQFSQGQEGLNQGNPFIATSGPGHLSHVPQQSPSMAPSLRHSVQQFHHH
PSTALHGESVAHSPRFSPNPPQQGAVRPQTLNFSSRSQTVPSPTINNSGQYSRYPYSNLNQGLVNNTGMNQNLGLTNNTPMNQSVPRYPN
AVGFPSNSGQGLMHQQPIHPSGSLNQMNTQTMHPSQPQGTYASPPPMSPMKAMSNPAGTPPPQVRPGSAGIPMEVGSYPNMPHPQPSHQP
PGAMGIGQRNMGPRNMQQSRPFIGMSSAPRELTGHMRPNGCPGVGLGDPQAIQERLIPGQQHPGQQPSFQQLPTCPPLQPHPGLHHQSSP
PHPHHQPWAQLHPSPQNTPQKVPVHQSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPG
TVGQIPHPLGWLVPQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQD
SKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKK
RKRDKQPGETNEHSECFLNPCLSLPPITDLSAPKKCRARFGLDQQNNWCGPCRRKKKCVRYIQGEGSCLSPPSSDGSLLDSPPPSPNLLG
SPPRDAKSQTEQTQPLSLSLKPDPLAHLSMMPPPPALLLAEATHKASALCPNGALDLPPAALQPAAPSSSIAQPSTSSLHSHSSLAGTQP

--------------------------------------------------------------

>16382_16382_18_CHD7-TCF7L2_CHD7_chr8_61655656_ENST00000423902_TCF7L2_chr10_114900943_ENST00000534894_length(amino acids)=877AA_BP=565
MWFGGAVCWKKMADPGMMSLFGEDGNIFSEGLEGLGECGYPENPVNPMGQQMPIDQGFASLQPSLHHPSTNQNQTKLTHFDHYNQYEQQK
MHLMDQPNRMMSNTPGNGLASPHSQYHTPPVPQVPHGGSGGGQMGVYPGMQNERHGQSFVDSSSMWGPRAVQVPDQIRAPYQQQQPQPQP
PQPAPSGPPAQGHPQHMQQMGSYMARGDFSMQQHGQPQQRMSQFSQGQEGLNQGNPFIATSGPGHLSHVPQQSPSMAPSLRHSVQQFHHH
PSTALHGESVAHSPRFSPNPPQQGAVRPQTLNFSSRSQTVPSPTINNSGQYSRYPYSNLNQGLVNNTGMNQNLGLTNNTPMNQSVPRYPN
AVGFPSNSGQGLMHQQPIHPSGSLNQMNTQTMHPSQPQGTYASPPPMSPMKAMSNPAGTPPPQVRPGSAGIPMEVGSYPNMPHPQPSHQP
PGAMGIGQRNMGPRNMQQSRPFIGMSSAPRELTGHMRPNGCPGVGLGDPQAIQERLIPGQQHPGQQPSFQQLPTCPPLQPHPGLHHQSSP
PHPHHQPWAQLHPSPQNTPQKVPVHQSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPG
TVGQIPHPLGWLVPQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQD
SKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKK

--------------------------------------------------------------

>16382_16382_19_CHD7-TCF7L2_CHD7_chr8_61655656_ENST00000423902_TCF7L2_chr10_114900943_ENST00000536810_length(amino acids)=984AA_BP=565
MWFGGAVCWKKMADPGMMSLFGEDGNIFSEGLEGLGECGYPENPVNPMGQQMPIDQGFASLQPSLHHPSTNQNQTKLTHFDHYNQYEQQK
MHLMDQPNRMMSNTPGNGLASPHSQYHTPPVPQVPHGGSGGGQMGVYPGMQNERHGQSFVDSSSMWGPRAVQVPDQIRAPYQQQQPQPQP
PQPAPSGPPAQGHPQHMQQMGSYMARGDFSMQQHGQPQQRMSQFSQGQEGLNQGNPFIATSGPGHLSHVPQQSPSMAPSLRHSVQQFHHH
PSTALHGESVAHSPRFSPNPPQQGAVRPQTLNFSSRSQTVPSPTINNSGQYSRYPYSNLNQGLVNNTGMNQNLGLTNNTPMNQSVPRYPN
AVGFPSNSGQGLMHQQPIHPSGSLNQMNTQTMHPSQPQGTYASPPPMSPMKAMSNPAGTPPPQVRPGSAGIPMEVGSYPNMPHPQPSHQP
PGAMGIGQRNMGPRNMQQSRPFIGMSSAPRELTGHMRPNGCPGVGLGDPQAIQERLIPGQQHPGQQPSFQQLPTCPPLQPHPGLHHQSSP
PHPHHQPWAQLHPSPQNTPQKVPVHQSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPG
TVGQIPHPLGWLVPQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQD
SKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKK
RKRDKQPGETNDLSAPKKCRARFGLDQQNNWCGPCRRKKKCVRYIQGEGSCLSPPSSDGSLLDSPPPSPNLLGSPPRDAKSQTEQTQPLS

--------------------------------------------------------------

>16382_16382_20_CHD7-TCF7L2_CHD7_chr8_61655656_ENST00000423902_TCF7L2_chr10_114900943_ENST00000538897_length(amino acids)=864AA_BP=565
MWFGGAVCWKKMADPGMMSLFGEDGNIFSEGLEGLGECGYPENPVNPMGQQMPIDQGFASLQPSLHHPSTNQNQTKLTHFDHYNQYEQQK
MHLMDQPNRMMSNTPGNGLASPHSQYHTPPVPQVPHGGSGGGQMGVYPGMQNERHGQSFVDSSSMWGPRAVQVPDQIRAPYQQQQPQPQP
PQPAPSGPPAQGHPQHMQQMGSYMARGDFSMQQHGQPQQRMSQFSQGQEGLNQGNPFIATSGPGHLSHVPQQSPSMAPSLRHSVQQFHHH
PSTALHGESVAHSPRFSPNPPQQGAVRPQTLNFSSRSQTVPSPTINNSGQYSRYPYSNLNQGLVNNTGMNQNLGLTNNTPMNQSVPRYPN
AVGFPSNSGQGLMHQQPIHPSGSLNQMNTQTMHPSQPQGTYASPPPMSPMKAMSNPAGTPPPQVRPGSAGIPMEVGSYPNMPHPQPSHQP
PGAMGIGQRNMGPRNMQQSRPFIGMSSAPRELTGHMRPNGCPGVGLGDPQAIQERLIPGQQHPGQQPSFQQLPTCPPLQPHPGLHHQSSP
PHPHHQPWAQLHPSPQNTPQKVPVHQSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPG
TVGQIPHPLGWLVPQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQD
SKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKK

--------------------------------------------------------------

>16382_16382_21_CHD7-TCF7L2_CHD7_chr8_61655656_ENST00000423902_TCF7L2_chr10_114900943_ENST00000543371_length(amino acids)=984AA_BP=565
MWFGGAVCWKKMADPGMMSLFGEDGNIFSEGLEGLGECGYPENPVNPMGQQMPIDQGFASLQPSLHHPSTNQNQTKLTHFDHYNQYEQQK
MHLMDQPNRMMSNTPGNGLASPHSQYHTPPVPQVPHGGSGGGQMGVYPGMQNERHGQSFVDSSSMWGPRAVQVPDQIRAPYQQQQPQPQP
PQPAPSGPPAQGHPQHMQQMGSYMARGDFSMQQHGQPQQRMSQFSQGQEGLNQGNPFIATSGPGHLSHVPQQSPSMAPSLRHSVQQFHHH
PSTALHGESVAHSPRFSPNPPQQGAVRPQTLNFSSRSQTVPSPTINNSGQYSRYPYSNLNQGLVNNTGMNQNLGLTNNTPMNQSVPRYPN
AVGFPSNSGQGLMHQQPIHPSGSLNQMNTQTMHPSQPQGTYASPPPMSPMKAMSNPAGTPPPQVRPGSAGIPMEVGSYPNMPHPQPSHQP
PGAMGIGQRNMGPRNMQQSRPFIGMSSAPRELTGHMRPNGCPGVGLGDPQAIQERLIPGQQHPGQQPSFQQLPTCPPLQPHPGLHHQSSP
PHPHHQPWAQLHPSPQNTPQKVPVHQSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPG
TVGQIPHPLGWLVPQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQD
SKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKK
RKRDKQPGETNDANTPKKCRALFGLDRQTLWCKPCRRKKKCVRYIQGEGSCLSPPSSDGSLLDSPPPSPNLLGSPPRDAKSQTEQTQPLS

--------------------------------------------------------------

>16382_16382_22_CHD7-TCF7L2_CHD7_chr8_61655656_ENST00000423902_TCF7L2_chr10_114900943_ENST00000545257_length(amino acids)=1001AA_BP=565
MWFGGAVCWKKMADPGMMSLFGEDGNIFSEGLEGLGECGYPENPVNPMGQQMPIDQGFASLQPSLHHPSTNQNQTKLTHFDHYNQYEQQK
MHLMDQPNRMMSNTPGNGLASPHSQYHTPPVPQVPHGGSGGGQMGVYPGMQNERHGQSFVDSSSMWGPRAVQVPDQIRAPYQQQQPQPQP
PQPAPSGPPAQGHPQHMQQMGSYMARGDFSMQQHGQPQQRMSQFSQGQEGLNQGNPFIATSGPGHLSHVPQQSPSMAPSLRHSVQQFHHH
PSTALHGESVAHSPRFSPNPPQQGAVRPQTLNFSSRSQTVPSPTINNSGQYSRYPYSNLNQGLVNNTGMNQNLGLTNNTPMNQSVPRYPN
AVGFPSNSGQGLMHQQPIHPSGSLNQMNTQTMHPSQPQGTYASPPPMSPMKAMSNPAGTPPPQVRPGSAGIPMEVGSYPNMPHPQPSHQP
PGAMGIGQRNMGPRNMQQSRPFIGMSSAPRELTGHMRPNGCPGVGLGDPQAIQERLIPGQQHPGQQPSFQQLPTCPPLQPHPGLHHQSSP
PHPHHQPWAQLHPSPQNTPQKVPVHQSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPG
TVGQIPHPLGWLVPQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQD
SKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKK
RKRDKQPGETNEHSECFLNPCLSLPPITDANTPKKCRALFGLDRQTLWCKPCRRKKKCVRYIQGEGSCLSPPSSDGSLLDSPPPSPNLLG
SPPRDAKSQTEQTQPLSLSLKPDPLAHLSMMPPPPALLLAEATHKASALCPNGALDLPPAALQPAAPSSSIAQPSTSSLHSHSSLAGTQP

--------------------------------------------------------------

>16382_16382_23_CHD7-TCF7L2_CHD7_chr8_61655656_ENST00000524602_TCF7L2_chr10_114900942_ENST00000349937_length(amino acids)=670AA_BP=565
MWFGGAVCWKKMADPGMMSLFGEDGNIFSEGLEGLGECGYPENPVNPMGQQMPIDQGFASLQPSLHHPSTNQNQTKLTHFDHYNQYEQQK
MHLMDQPNRMMSNTPGNGLASPHSQYHTPPVPQVPHGGSGGGQMGVYPGMQNERHGQSFVDSSSMWGPRAVQVPDQIRAPYQQQQPQPQP
PQPAPSGPPAQGHPQHMQQMGSYMARGDFSMQQHGQPQQRMSQFSQGQEGLNQGNPFIATSGPGHLSHVPQQSPSMAPSLRHSVQQFHHH
PSTALHGESVAHSPRFSPNPPQQGAVRPQTLNFSSRSQTVPSPTINNSGQYSRYPYSNLNQGLVNNTGMNQNLGLTNNTPMNQSVPRYPN
AVGFPSNSGQGLMHQQPIHPSGSLNQMNTQTMHPSQPQGTYASPPPMSPMKAMSNPAGTPPPQVRPGSAGIPMEVGSYPNMPHPQPSHQP
PGAMGIGQRNMGPRNMQQSRPFIGMSSAPRELTGHMRPNGCPGVGLGDPQAIQERLIPGQQHPGQQPSFQQLPTCPPLQPHPGLHHQSSP
PHPHHQPWAQLHPSPQNTPQKVPVHQSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPG

--------------------------------------------------------------

>16382_16382_24_CHD7-TCF7L2_CHD7_chr8_61655656_ENST00000524602_TCF7L2_chr10_114900942_ENST00000352065_length(amino acids)=864AA_BP=565
MWFGGAVCWKKMADPGMMSLFGEDGNIFSEGLEGLGECGYPENPVNPMGQQMPIDQGFASLQPSLHHPSTNQNQTKLTHFDHYNQYEQQK
MHLMDQPNRMMSNTPGNGLASPHSQYHTPPVPQVPHGGSGGGQMGVYPGMQNERHGQSFVDSSSMWGPRAVQVPDQIRAPYQQQQPQPQP
PQPAPSGPPAQGHPQHMQQMGSYMARGDFSMQQHGQPQQRMSQFSQGQEGLNQGNPFIATSGPGHLSHVPQQSPSMAPSLRHSVQQFHHH
PSTALHGESVAHSPRFSPNPPQQGAVRPQTLNFSSRSQTVPSPTINNSGQYSRYPYSNLNQGLVNNTGMNQNLGLTNNTPMNQSVPRYPN
AVGFPSNSGQGLMHQQPIHPSGSLNQMNTQTMHPSQPQGTYASPPPMSPMKAMSNPAGTPPPQVRPGSAGIPMEVGSYPNMPHPQPSHQP
PGAMGIGQRNMGPRNMQQSRPFIGMSSAPRELTGHMRPNGCPGVGLGDPQAIQERLIPGQQHPGQQPSFQQLPTCPPLQPHPGLHHQSSP
PHPHHQPWAQLHPSPQNTPQKVPVHQSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPG
TVGQIPHPLGWLVPQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQD
SKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKK

--------------------------------------------------------------

>16382_16382_25_CHD7-TCF7L2_CHD7_chr8_61655656_ENST00000524602_TCF7L2_chr10_114900942_ENST00000355717_length(amino acids)=847AA_BP=565
MWFGGAVCWKKMADPGMMSLFGEDGNIFSEGLEGLGECGYPENPVNPMGQQMPIDQGFASLQPSLHHPSTNQNQTKLTHFDHYNQYEQQK
MHLMDQPNRMMSNTPGNGLASPHSQYHTPPVPQVPHGGSGGGQMGVYPGMQNERHGQSFVDSSSMWGPRAVQVPDQIRAPYQQQQPQPQP
PQPAPSGPPAQGHPQHMQQMGSYMARGDFSMQQHGQPQQRMSQFSQGQEGLNQGNPFIATSGPGHLSHVPQQSPSMAPSLRHSVQQFHHH
PSTALHGESVAHSPRFSPNPPQQGAVRPQTLNFSSRSQTVPSPTINNSGQYSRYPYSNLNQGLVNNTGMNQNLGLTNNTPMNQSVPRYPN
AVGFPSNSGQGLMHQQPIHPSGSLNQMNTQTMHPSQPQGTYASPPPMSPMKAMSNPAGTPPPQVRPGSAGIPMEVGSYPNMPHPQPSHQP
PGAMGIGQRNMGPRNMQQSRPFIGMSSAPRELTGHMRPNGCPGVGLGDPQAIQERLIPGQQHPGQQPSFQQLPTCPPLQPHPGLHHQSSP
PHPHHQPWAQLHPSPQNTPQKVPVHQSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPG
TVGQIPHPLGWLVPQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQD
SKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKK

--------------------------------------------------------------

>16382_16382_26_CHD7-TCF7L2_CHD7_chr8_61655656_ENST00000524602_TCF7L2_chr10_114900942_ENST00000355995_length(amino acids)=1001AA_BP=565
MWFGGAVCWKKMADPGMMSLFGEDGNIFSEGLEGLGECGYPENPVNPMGQQMPIDQGFASLQPSLHHPSTNQNQTKLTHFDHYNQYEQQK
MHLMDQPNRMMSNTPGNGLASPHSQYHTPPVPQVPHGGSGGGQMGVYPGMQNERHGQSFVDSSSMWGPRAVQVPDQIRAPYQQQQPQPQP
PQPAPSGPPAQGHPQHMQQMGSYMARGDFSMQQHGQPQQRMSQFSQGQEGLNQGNPFIATSGPGHLSHVPQQSPSMAPSLRHSVQQFHHH
PSTALHGESVAHSPRFSPNPPQQGAVRPQTLNFSSRSQTVPSPTINNSGQYSRYPYSNLNQGLVNNTGMNQNLGLTNNTPMNQSVPRYPN
AVGFPSNSGQGLMHQQPIHPSGSLNQMNTQTMHPSQPQGTYASPPPMSPMKAMSNPAGTPPPQVRPGSAGIPMEVGSYPNMPHPQPSHQP
PGAMGIGQRNMGPRNMQQSRPFIGMSSAPRELTGHMRPNGCPGVGLGDPQAIQERLIPGQQHPGQQPSFQQLPTCPPLQPHPGLHHQSSP
PHPHHQPWAQLHPSPQNTPQKVPVHQSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPG
TVGQIPHPLGWLVPQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQD
SKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKK
RKRDKQPGETNEHSECFLNPCLSLPPITDLSAPKKCRARFGLDQQNNWCGPCRRKKKCVRYIQGEGSCLSPPSSDGSLLDSPPPSPNLLG
SPPRDAKSQTEQTQPLSLSLKPDPLAHLSMMPPPPALLLAEATHKASALCPNGALDLPPAALQPAAPSSSIAQPSTSSLHSHSSLAGTQP

--------------------------------------------------------------

>16382_16382_27_CHD7-TCF7L2_CHD7_chr8_61655656_ENST00000524602_TCF7L2_chr10_114900942_ENST00000369395_length(amino acids)=674AA_BP=565
MWFGGAVCWKKMADPGMMSLFGEDGNIFSEGLEGLGECGYPENPVNPMGQQMPIDQGFASLQPSLHHPSTNQNQTKLTHFDHYNQYEQQK
MHLMDQPNRMMSNTPGNGLASPHSQYHTPPVPQVPHGGSGGGQMGVYPGMQNERHGQSFVDSSSMWGPRAVQVPDQIRAPYQQQQPQPQP
PQPAPSGPPAQGHPQHMQQMGSYMARGDFSMQQHGQPQQRMSQFSQGQEGLNQGNPFIATSGPGHLSHVPQQSPSMAPSLRHSVQQFHHH
PSTALHGESVAHSPRFSPNPPQQGAVRPQTLNFSSRSQTVPSPTINNSGQYSRYPYSNLNQGLVNNTGMNQNLGLTNNTPMNQSVPRYPN
AVGFPSNSGQGLMHQQPIHPSGSLNQMNTQTMHPSQPQGTYASPPPMSPMKAMSNPAGTPPPQVRPGSAGIPMEVGSYPNMPHPQPSHQP
PGAMGIGQRNMGPRNMQQSRPFIGMSSAPRELTGHMRPNGCPGVGLGDPQAIQERLIPGQQHPGQQPSFQQLPTCPPLQPHPGLHHQSSP
PHPHHQPWAQLHPSPQNTPQKVPVHQSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPG

--------------------------------------------------------------

>16382_16382_28_CHD7-TCF7L2_CHD7_chr8_61655656_ENST00000524602_TCF7L2_chr10_114900942_ENST00000369397_length(amino acids)=1001AA_BP=565
MWFGGAVCWKKMADPGMMSLFGEDGNIFSEGLEGLGECGYPENPVNPMGQQMPIDQGFASLQPSLHHPSTNQNQTKLTHFDHYNQYEQQK
MHLMDQPNRMMSNTPGNGLASPHSQYHTPPVPQVPHGGSGGGQMGVYPGMQNERHGQSFVDSSSMWGPRAVQVPDQIRAPYQQQQPQPQP
PQPAPSGPPAQGHPQHMQQMGSYMARGDFSMQQHGQPQQRMSQFSQGQEGLNQGNPFIATSGPGHLSHVPQQSPSMAPSLRHSVQQFHHH
PSTALHGESVAHSPRFSPNPPQQGAVRPQTLNFSSRSQTVPSPTINNSGQYSRYPYSNLNQGLVNNTGMNQNLGLTNNTPMNQSVPRYPN
AVGFPSNSGQGLMHQQPIHPSGSLNQMNTQTMHPSQPQGTYASPPPMSPMKAMSNPAGTPPPQVRPGSAGIPMEVGSYPNMPHPQPSHQP
PGAMGIGQRNMGPRNMQQSRPFIGMSSAPRELTGHMRPNGCPGVGLGDPQAIQERLIPGQQHPGQQPSFQQLPTCPPLQPHPGLHHQSSP
PHPHHQPWAQLHPSPQNTPQKVPVHQSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPG
TVGQIPHPLGWLVPQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQD
SKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKK
RKRDKQPGETNEHSECFLNPCLSLPPITDLSAPKKCRARFGLDQQNNWCGPCRRKKKCVRYIQGEGSCLSPPSSDGSLLDSPPPSPNLLG
SPPRDAKSQTEQTQPLSLSLKPDPLAHLSMMPPPPALLLAEATHKASALCPNGALDLPPAALQPAAPSSSIAQPSTSSLHSHSSLAGTQP

--------------------------------------------------------------

>16382_16382_29_CHD7-TCF7L2_CHD7_chr8_61655656_ENST00000524602_TCF7L2_chr10_114900942_ENST00000534894_length(amino acids)=877AA_BP=565
MWFGGAVCWKKMADPGMMSLFGEDGNIFSEGLEGLGECGYPENPVNPMGQQMPIDQGFASLQPSLHHPSTNQNQTKLTHFDHYNQYEQQK
MHLMDQPNRMMSNTPGNGLASPHSQYHTPPVPQVPHGGSGGGQMGVYPGMQNERHGQSFVDSSSMWGPRAVQVPDQIRAPYQQQQPQPQP
PQPAPSGPPAQGHPQHMQQMGSYMARGDFSMQQHGQPQQRMSQFSQGQEGLNQGNPFIATSGPGHLSHVPQQSPSMAPSLRHSVQQFHHH
PSTALHGESVAHSPRFSPNPPQQGAVRPQTLNFSSRSQTVPSPTINNSGQYSRYPYSNLNQGLVNNTGMNQNLGLTNNTPMNQSVPRYPN
AVGFPSNSGQGLMHQQPIHPSGSLNQMNTQTMHPSQPQGTYASPPPMSPMKAMSNPAGTPPPQVRPGSAGIPMEVGSYPNMPHPQPSHQP
PGAMGIGQRNMGPRNMQQSRPFIGMSSAPRELTGHMRPNGCPGVGLGDPQAIQERLIPGQQHPGQQPSFQQLPTCPPLQPHPGLHHQSSP
PHPHHQPWAQLHPSPQNTPQKVPVHQSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPG
TVGQIPHPLGWLVPQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQD
SKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKK

--------------------------------------------------------------

>16382_16382_30_CHD7-TCF7L2_CHD7_chr8_61655656_ENST00000524602_TCF7L2_chr10_114900942_ENST00000536810_length(amino acids)=984AA_BP=565
MWFGGAVCWKKMADPGMMSLFGEDGNIFSEGLEGLGECGYPENPVNPMGQQMPIDQGFASLQPSLHHPSTNQNQTKLTHFDHYNQYEQQK
MHLMDQPNRMMSNTPGNGLASPHSQYHTPPVPQVPHGGSGGGQMGVYPGMQNERHGQSFVDSSSMWGPRAVQVPDQIRAPYQQQQPQPQP
PQPAPSGPPAQGHPQHMQQMGSYMARGDFSMQQHGQPQQRMSQFSQGQEGLNQGNPFIATSGPGHLSHVPQQSPSMAPSLRHSVQQFHHH
PSTALHGESVAHSPRFSPNPPQQGAVRPQTLNFSSRSQTVPSPTINNSGQYSRYPYSNLNQGLVNNTGMNQNLGLTNNTPMNQSVPRYPN
AVGFPSNSGQGLMHQQPIHPSGSLNQMNTQTMHPSQPQGTYASPPPMSPMKAMSNPAGTPPPQVRPGSAGIPMEVGSYPNMPHPQPSHQP
PGAMGIGQRNMGPRNMQQSRPFIGMSSAPRELTGHMRPNGCPGVGLGDPQAIQERLIPGQQHPGQQPSFQQLPTCPPLQPHPGLHHQSSP
PHPHHQPWAQLHPSPQNTPQKVPVHQSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPG
TVGQIPHPLGWLVPQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQD
SKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKK
RKRDKQPGETNDLSAPKKCRARFGLDQQNNWCGPCRRKKKCVRYIQGEGSCLSPPSSDGSLLDSPPPSPNLLGSPPRDAKSQTEQTQPLS

--------------------------------------------------------------

>16382_16382_31_CHD7-TCF7L2_CHD7_chr8_61655656_ENST00000524602_TCF7L2_chr10_114900942_ENST00000538897_length(amino acids)=864AA_BP=565
MWFGGAVCWKKMADPGMMSLFGEDGNIFSEGLEGLGECGYPENPVNPMGQQMPIDQGFASLQPSLHHPSTNQNQTKLTHFDHYNQYEQQK
MHLMDQPNRMMSNTPGNGLASPHSQYHTPPVPQVPHGGSGGGQMGVYPGMQNERHGQSFVDSSSMWGPRAVQVPDQIRAPYQQQQPQPQP
PQPAPSGPPAQGHPQHMQQMGSYMARGDFSMQQHGQPQQRMSQFSQGQEGLNQGNPFIATSGPGHLSHVPQQSPSMAPSLRHSVQQFHHH
PSTALHGESVAHSPRFSPNPPQQGAVRPQTLNFSSRSQTVPSPTINNSGQYSRYPYSNLNQGLVNNTGMNQNLGLTNNTPMNQSVPRYPN
AVGFPSNSGQGLMHQQPIHPSGSLNQMNTQTMHPSQPQGTYASPPPMSPMKAMSNPAGTPPPQVRPGSAGIPMEVGSYPNMPHPQPSHQP
PGAMGIGQRNMGPRNMQQSRPFIGMSSAPRELTGHMRPNGCPGVGLGDPQAIQERLIPGQQHPGQQPSFQQLPTCPPLQPHPGLHHQSSP
PHPHHQPWAQLHPSPQNTPQKVPVHQSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPG
TVGQIPHPLGWLVPQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQD
SKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKK

--------------------------------------------------------------

>16382_16382_32_CHD7-TCF7L2_CHD7_chr8_61655656_ENST00000524602_TCF7L2_chr10_114900942_ENST00000543371_length(amino acids)=984AA_BP=565
MWFGGAVCWKKMADPGMMSLFGEDGNIFSEGLEGLGECGYPENPVNPMGQQMPIDQGFASLQPSLHHPSTNQNQTKLTHFDHYNQYEQQK
MHLMDQPNRMMSNTPGNGLASPHSQYHTPPVPQVPHGGSGGGQMGVYPGMQNERHGQSFVDSSSMWGPRAVQVPDQIRAPYQQQQPQPQP
PQPAPSGPPAQGHPQHMQQMGSYMARGDFSMQQHGQPQQRMSQFSQGQEGLNQGNPFIATSGPGHLSHVPQQSPSMAPSLRHSVQQFHHH
PSTALHGESVAHSPRFSPNPPQQGAVRPQTLNFSSRSQTVPSPTINNSGQYSRYPYSNLNQGLVNNTGMNQNLGLTNNTPMNQSVPRYPN
AVGFPSNSGQGLMHQQPIHPSGSLNQMNTQTMHPSQPQGTYASPPPMSPMKAMSNPAGTPPPQVRPGSAGIPMEVGSYPNMPHPQPSHQP
PGAMGIGQRNMGPRNMQQSRPFIGMSSAPRELTGHMRPNGCPGVGLGDPQAIQERLIPGQQHPGQQPSFQQLPTCPPLQPHPGLHHQSSP
PHPHHQPWAQLHPSPQNTPQKVPVHQSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPG
TVGQIPHPLGWLVPQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQD
SKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKK
RKRDKQPGETNDANTPKKCRALFGLDRQTLWCKPCRRKKKCVRYIQGEGSCLSPPSSDGSLLDSPPPSPNLLGSPPRDAKSQTEQTQPLS

--------------------------------------------------------------

>16382_16382_33_CHD7-TCF7L2_CHD7_chr8_61655656_ENST00000524602_TCF7L2_chr10_114900942_ENST00000545257_length(amino acids)=1001AA_BP=565
MWFGGAVCWKKMADPGMMSLFGEDGNIFSEGLEGLGECGYPENPVNPMGQQMPIDQGFASLQPSLHHPSTNQNQTKLTHFDHYNQYEQQK
MHLMDQPNRMMSNTPGNGLASPHSQYHTPPVPQVPHGGSGGGQMGVYPGMQNERHGQSFVDSSSMWGPRAVQVPDQIRAPYQQQQPQPQP
PQPAPSGPPAQGHPQHMQQMGSYMARGDFSMQQHGQPQQRMSQFSQGQEGLNQGNPFIATSGPGHLSHVPQQSPSMAPSLRHSVQQFHHH
PSTALHGESVAHSPRFSPNPPQQGAVRPQTLNFSSRSQTVPSPTINNSGQYSRYPYSNLNQGLVNNTGMNQNLGLTNNTPMNQSVPRYPN
AVGFPSNSGQGLMHQQPIHPSGSLNQMNTQTMHPSQPQGTYASPPPMSPMKAMSNPAGTPPPQVRPGSAGIPMEVGSYPNMPHPQPSHQP
PGAMGIGQRNMGPRNMQQSRPFIGMSSAPRELTGHMRPNGCPGVGLGDPQAIQERLIPGQQHPGQQPSFQQLPTCPPLQPHPGLHHQSSP
PHPHHQPWAQLHPSPQNTPQKVPVHQSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPG
TVGQIPHPLGWLVPQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQD
SKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKK
RKRDKQPGETNEHSECFLNPCLSLPPITDANTPKKCRALFGLDRQTLWCKPCRRKKKCVRYIQGEGSCLSPPSSDGSLLDSPPPSPNLLG
SPPRDAKSQTEQTQPLSLSLKPDPLAHLSMMPPPPALLLAEATHKASALCPNGALDLPPAALQPAAPSSSIAQPSTSSLHSHSSLAGTQP

--------------------------------------------------------------

>16382_16382_34_CHD7-TCF7L2_CHD7_chr8_61655656_ENST00000524602_TCF7L2_chr10_114900943_ENST00000349937_length(amino acids)=670AA_BP=565
MWFGGAVCWKKMADPGMMSLFGEDGNIFSEGLEGLGECGYPENPVNPMGQQMPIDQGFASLQPSLHHPSTNQNQTKLTHFDHYNQYEQQK
MHLMDQPNRMMSNTPGNGLASPHSQYHTPPVPQVPHGGSGGGQMGVYPGMQNERHGQSFVDSSSMWGPRAVQVPDQIRAPYQQQQPQPQP
PQPAPSGPPAQGHPQHMQQMGSYMARGDFSMQQHGQPQQRMSQFSQGQEGLNQGNPFIATSGPGHLSHVPQQSPSMAPSLRHSVQQFHHH
PSTALHGESVAHSPRFSPNPPQQGAVRPQTLNFSSRSQTVPSPTINNSGQYSRYPYSNLNQGLVNNTGMNQNLGLTNNTPMNQSVPRYPN
AVGFPSNSGQGLMHQQPIHPSGSLNQMNTQTMHPSQPQGTYASPPPMSPMKAMSNPAGTPPPQVRPGSAGIPMEVGSYPNMPHPQPSHQP
PGAMGIGQRNMGPRNMQQSRPFIGMSSAPRELTGHMRPNGCPGVGLGDPQAIQERLIPGQQHPGQQPSFQQLPTCPPLQPHPGLHHQSSP
PHPHHQPWAQLHPSPQNTPQKVPVHQSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPG

--------------------------------------------------------------

>16382_16382_35_CHD7-TCF7L2_CHD7_chr8_61655656_ENST00000524602_TCF7L2_chr10_114900943_ENST00000352065_length(amino acids)=864AA_BP=565
MWFGGAVCWKKMADPGMMSLFGEDGNIFSEGLEGLGECGYPENPVNPMGQQMPIDQGFASLQPSLHHPSTNQNQTKLTHFDHYNQYEQQK
MHLMDQPNRMMSNTPGNGLASPHSQYHTPPVPQVPHGGSGGGQMGVYPGMQNERHGQSFVDSSSMWGPRAVQVPDQIRAPYQQQQPQPQP
PQPAPSGPPAQGHPQHMQQMGSYMARGDFSMQQHGQPQQRMSQFSQGQEGLNQGNPFIATSGPGHLSHVPQQSPSMAPSLRHSVQQFHHH
PSTALHGESVAHSPRFSPNPPQQGAVRPQTLNFSSRSQTVPSPTINNSGQYSRYPYSNLNQGLVNNTGMNQNLGLTNNTPMNQSVPRYPN
AVGFPSNSGQGLMHQQPIHPSGSLNQMNTQTMHPSQPQGTYASPPPMSPMKAMSNPAGTPPPQVRPGSAGIPMEVGSYPNMPHPQPSHQP
PGAMGIGQRNMGPRNMQQSRPFIGMSSAPRELTGHMRPNGCPGVGLGDPQAIQERLIPGQQHPGQQPSFQQLPTCPPLQPHPGLHHQSSP
PHPHHQPWAQLHPSPQNTPQKVPVHQSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPG
TVGQIPHPLGWLVPQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQD
SKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKK

--------------------------------------------------------------

>16382_16382_36_CHD7-TCF7L2_CHD7_chr8_61655656_ENST00000524602_TCF7L2_chr10_114900943_ENST00000355717_length(amino acids)=847AA_BP=565
MWFGGAVCWKKMADPGMMSLFGEDGNIFSEGLEGLGECGYPENPVNPMGQQMPIDQGFASLQPSLHHPSTNQNQTKLTHFDHYNQYEQQK
MHLMDQPNRMMSNTPGNGLASPHSQYHTPPVPQVPHGGSGGGQMGVYPGMQNERHGQSFVDSSSMWGPRAVQVPDQIRAPYQQQQPQPQP
PQPAPSGPPAQGHPQHMQQMGSYMARGDFSMQQHGQPQQRMSQFSQGQEGLNQGNPFIATSGPGHLSHVPQQSPSMAPSLRHSVQQFHHH
PSTALHGESVAHSPRFSPNPPQQGAVRPQTLNFSSRSQTVPSPTINNSGQYSRYPYSNLNQGLVNNTGMNQNLGLTNNTPMNQSVPRYPN
AVGFPSNSGQGLMHQQPIHPSGSLNQMNTQTMHPSQPQGTYASPPPMSPMKAMSNPAGTPPPQVRPGSAGIPMEVGSYPNMPHPQPSHQP
PGAMGIGQRNMGPRNMQQSRPFIGMSSAPRELTGHMRPNGCPGVGLGDPQAIQERLIPGQQHPGQQPSFQQLPTCPPLQPHPGLHHQSSP
PHPHHQPWAQLHPSPQNTPQKVPVHQSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPG
TVGQIPHPLGWLVPQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQD
SKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKK

--------------------------------------------------------------

>16382_16382_37_CHD7-TCF7L2_CHD7_chr8_61655656_ENST00000524602_TCF7L2_chr10_114900943_ENST00000355995_length(amino acids)=1001AA_BP=565
MWFGGAVCWKKMADPGMMSLFGEDGNIFSEGLEGLGECGYPENPVNPMGQQMPIDQGFASLQPSLHHPSTNQNQTKLTHFDHYNQYEQQK
MHLMDQPNRMMSNTPGNGLASPHSQYHTPPVPQVPHGGSGGGQMGVYPGMQNERHGQSFVDSSSMWGPRAVQVPDQIRAPYQQQQPQPQP
PQPAPSGPPAQGHPQHMQQMGSYMARGDFSMQQHGQPQQRMSQFSQGQEGLNQGNPFIATSGPGHLSHVPQQSPSMAPSLRHSVQQFHHH
PSTALHGESVAHSPRFSPNPPQQGAVRPQTLNFSSRSQTVPSPTINNSGQYSRYPYSNLNQGLVNNTGMNQNLGLTNNTPMNQSVPRYPN
AVGFPSNSGQGLMHQQPIHPSGSLNQMNTQTMHPSQPQGTYASPPPMSPMKAMSNPAGTPPPQVRPGSAGIPMEVGSYPNMPHPQPSHQP
PGAMGIGQRNMGPRNMQQSRPFIGMSSAPRELTGHMRPNGCPGVGLGDPQAIQERLIPGQQHPGQQPSFQQLPTCPPLQPHPGLHHQSSP
PHPHHQPWAQLHPSPQNTPQKVPVHQSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPG
TVGQIPHPLGWLVPQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQD
SKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKK
RKRDKQPGETNEHSECFLNPCLSLPPITDLSAPKKCRARFGLDQQNNWCGPCRRKKKCVRYIQGEGSCLSPPSSDGSLLDSPPPSPNLLG
SPPRDAKSQTEQTQPLSLSLKPDPLAHLSMMPPPPALLLAEATHKASALCPNGALDLPPAALQPAAPSSSIAQPSTSSLHSHSSLAGTQP

--------------------------------------------------------------

>16382_16382_38_CHD7-TCF7L2_CHD7_chr8_61655656_ENST00000524602_TCF7L2_chr10_114900943_ENST00000369395_length(amino acids)=674AA_BP=565
MWFGGAVCWKKMADPGMMSLFGEDGNIFSEGLEGLGECGYPENPVNPMGQQMPIDQGFASLQPSLHHPSTNQNQTKLTHFDHYNQYEQQK
MHLMDQPNRMMSNTPGNGLASPHSQYHTPPVPQVPHGGSGGGQMGVYPGMQNERHGQSFVDSSSMWGPRAVQVPDQIRAPYQQQQPQPQP
PQPAPSGPPAQGHPQHMQQMGSYMARGDFSMQQHGQPQQRMSQFSQGQEGLNQGNPFIATSGPGHLSHVPQQSPSMAPSLRHSVQQFHHH
PSTALHGESVAHSPRFSPNPPQQGAVRPQTLNFSSRSQTVPSPTINNSGQYSRYPYSNLNQGLVNNTGMNQNLGLTNNTPMNQSVPRYPN
AVGFPSNSGQGLMHQQPIHPSGSLNQMNTQTMHPSQPQGTYASPPPMSPMKAMSNPAGTPPPQVRPGSAGIPMEVGSYPNMPHPQPSHQP
PGAMGIGQRNMGPRNMQQSRPFIGMSSAPRELTGHMRPNGCPGVGLGDPQAIQERLIPGQQHPGQQPSFQQLPTCPPLQPHPGLHHQSSP
PHPHHQPWAQLHPSPQNTPQKVPVHQSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPG

--------------------------------------------------------------

>16382_16382_39_CHD7-TCF7L2_CHD7_chr8_61655656_ENST00000524602_TCF7L2_chr10_114900943_ENST00000369397_length(amino acids)=1001AA_BP=565
MWFGGAVCWKKMADPGMMSLFGEDGNIFSEGLEGLGECGYPENPVNPMGQQMPIDQGFASLQPSLHHPSTNQNQTKLTHFDHYNQYEQQK
MHLMDQPNRMMSNTPGNGLASPHSQYHTPPVPQVPHGGSGGGQMGVYPGMQNERHGQSFVDSSSMWGPRAVQVPDQIRAPYQQQQPQPQP
PQPAPSGPPAQGHPQHMQQMGSYMARGDFSMQQHGQPQQRMSQFSQGQEGLNQGNPFIATSGPGHLSHVPQQSPSMAPSLRHSVQQFHHH
PSTALHGESVAHSPRFSPNPPQQGAVRPQTLNFSSRSQTVPSPTINNSGQYSRYPYSNLNQGLVNNTGMNQNLGLTNNTPMNQSVPRYPN
AVGFPSNSGQGLMHQQPIHPSGSLNQMNTQTMHPSQPQGTYASPPPMSPMKAMSNPAGTPPPQVRPGSAGIPMEVGSYPNMPHPQPSHQP
PGAMGIGQRNMGPRNMQQSRPFIGMSSAPRELTGHMRPNGCPGVGLGDPQAIQERLIPGQQHPGQQPSFQQLPTCPPLQPHPGLHHQSSP
PHPHHQPWAQLHPSPQNTPQKVPVHQSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPG
TVGQIPHPLGWLVPQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQD
SKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKK
RKRDKQPGETNEHSECFLNPCLSLPPITDLSAPKKCRARFGLDQQNNWCGPCRRKKKCVRYIQGEGSCLSPPSSDGSLLDSPPPSPNLLG
SPPRDAKSQTEQTQPLSLSLKPDPLAHLSMMPPPPALLLAEATHKASALCPNGALDLPPAALQPAAPSSSIAQPSTSSLHSHSSLAGTQP

--------------------------------------------------------------

>16382_16382_40_CHD7-TCF7L2_CHD7_chr8_61655656_ENST00000524602_TCF7L2_chr10_114900943_ENST00000534894_length(amino acids)=877AA_BP=565
MWFGGAVCWKKMADPGMMSLFGEDGNIFSEGLEGLGECGYPENPVNPMGQQMPIDQGFASLQPSLHHPSTNQNQTKLTHFDHYNQYEQQK
MHLMDQPNRMMSNTPGNGLASPHSQYHTPPVPQVPHGGSGGGQMGVYPGMQNERHGQSFVDSSSMWGPRAVQVPDQIRAPYQQQQPQPQP
PQPAPSGPPAQGHPQHMQQMGSYMARGDFSMQQHGQPQQRMSQFSQGQEGLNQGNPFIATSGPGHLSHVPQQSPSMAPSLRHSVQQFHHH
PSTALHGESVAHSPRFSPNPPQQGAVRPQTLNFSSRSQTVPSPTINNSGQYSRYPYSNLNQGLVNNTGMNQNLGLTNNTPMNQSVPRYPN
AVGFPSNSGQGLMHQQPIHPSGSLNQMNTQTMHPSQPQGTYASPPPMSPMKAMSNPAGTPPPQVRPGSAGIPMEVGSYPNMPHPQPSHQP
PGAMGIGQRNMGPRNMQQSRPFIGMSSAPRELTGHMRPNGCPGVGLGDPQAIQERLIPGQQHPGQQPSFQQLPTCPPLQPHPGLHHQSSP
PHPHHQPWAQLHPSPQNTPQKVPVHQSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPG
TVGQIPHPLGWLVPQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQD
SKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKK

--------------------------------------------------------------

>16382_16382_41_CHD7-TCF7L2_CHD7_chr8_61655656_ENST00000524602_TCF7L2_chr10_114900943_ENST00000536810_length(amino acids)=984AA_BP=565
MWFGGAVCWKKMADPGMMSLFGEDGNIFSEGLEGLGECGYPENPVNPMGQQMPIDQGFASLQPSLHHPSTNQNQTKLTHFDHYNQYEQQK
MHLMDQPNRMMSNTPGNGLASPHSQYHTPPVPQVPHGGSGGGQMGVYPGMQNERHGQSFVDSSSMWGPRAVQVPDQIRAPYQQQQPQPQP
PQPAPSGPPAQGHPQHMQQMGSYMARGDFSMQQHGQPQQRMSQFSQGQEGLNQGNPFIATSGPGHLSHVPQQSPSMAPSLRHSVQQFHHH
PSTALHGESVAHSPRFSPNPPQQGAVRPQTLNFSSRSQTVPSPTINNSGQYSRYPYSNLNQGLVNNTGMNQNLGLTNNTPMNQSVPRYPN
AVGFPSNSGQGLMHQQPIHPSGSLNQMNTQTMHPSQPQGTYASPPPMSPMKAMSNPAGTPPPQVRPGSAGIPMEVGSYPNMPHPQPSHQP
PGAMGIGQRNMGPRNMQQSRPFIGMSSAPRELTGHMRPNGCPGVGLGDPQAIQERLIPGQQHPGQQPSFQQLPTCPPLQPHPGLHHQSSP
PHPHHQPWAQLHPSPQNTPQKVPVHQSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPG
TVGQIPHPLGWLVPQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQD
SKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKK
RKRDKQPGETNDLSAPKKCRARFGLDQQNNWCGPCRRKKKCVRYIQGEGSCLSPPSSDGSLLDSPPPSPNLLGSPPRDAKSQTEQTQPLS

--------------------------------------------------------------

>16382_16382_42_CHD7-TCF7L2_CHD7_chr8_61655656_ENST00000524602_TCF7L2_chr10_114900943_ENST00000538897_length(amino acids)=864AA_BP=565
MWFGGAVCWKKMADPGMMSLFGEDGNIFSEGLEGLGECGYPENPVNPMGQQMPIDQGFASLQPSLHHPSTNQNQTKLTHFDHYNQYEQQK
MHLMDQPNRMMSNTPGNGLASPHSQYHTPPVPQVPHGGSGGGQMGVYPGMQNERHGQSFVDSSSMWGPRAVQVPDQIRAPYQQQQPQPQP
PQPAPSGPPAQGHPQHMQQMGSYMARGDFSMQQHGQPQQRMSQFSQGQEGLNQGNPFIATSGPGHLSHVPQQSPSMAPSLRHSVQQFHHH
PSTALHGESVAHSPRFSPNPPQQGAVRPQTLNFSSRSQTVPSPTINNSGQYSRYPYSNLNQGLVNNTGMNQNLGLTNNTPMNQSVPRYPN
AVGFPSNSGQGLMHQQPIHPSGSLNQMNTQTMHPSQPQGTYASPPPMSPMKAMSNPAGTPPPQVRPGSAGIPMEVGSYPNMPHPQPSHQP
PGAMGIGQRNMGPRNMQQSRPFIGMSSAPRELTGHMRPNGCPGVGLGDPQAIQERLIPGQQHPGQQPSFQQLPTCPPLQPHPGLHHQSSP
PHPHHQPWAQLHPSPQNTPQKVPVHQSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPG
TVGQIPHPLGWLVPQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQD
SKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKK

--------------------------------------------------------------

>16382_16382_43_CHD7-TCF7L2_CHD7_chr8_61655656_ENST00000524602_TCF7L2_chr10_114900943_ENST00000543371_length(amino acids)=984AA_BP=565
MWFGGAVCWKKMADPGMMSLFGEDGNIFSEGLEGLGECGYPENPVNPMGQQMPIDQGFASLQPSLHHPSTNQNQTKLTHFDHYNQYEQQK
MHLMDQPNRMMSNTPGNGLASPHSQYHTPPVPQVPHGGSGGGQMGVYPGMQNERHGQSFVDSSSMWGPRAVQVPDQIRAPYQQQQPQPQP
PQPAPSGPPAQGHPQHMQQMGSYMARGDFSMQQHGQPQQRMSQFSQGQEGLNQGNPFIATSGPGHLSHVPQQSPSMAPSLRHSVQQFHHH
PSTALHGESVAHSPRFSPNPPQQGAVRPQTLNFSSRSQTVPSPTINNSGQYSRYPYSNLNQGLVNNTGMNQNLGLTNNTPMNQSVPRYPN
AVGFPSNSGQGLMHQQPIHPSGSLNQMNTQTMHPSQPQGTYASPPPMSPMKAMSNPAGTPPPQVRPGSAGIPMEVGSYPNMPHPQPSHQP
PGAMGIGQRNMGPRNMQQSRPFIGMSSAPRELTGHMRPNGCPGVGLGDPQAIQERLIPGQQHPGQQPSFQQLPTCPPLQPHPGLHHQSSP
PHPHHQPWAQLHPSPQNTPQKVPVHQSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPG
TVGQIPHPLGWLVPQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQD
SKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKK
RKRDKQPGETNDANTPKKCRALFGLDRQTLWCKPCRRKKKCVRYIQGEGSCLSPPSSDGSLLDSPPPSPNLLGSPPRDAKSQTEQTQPLS

--------------------------------------------------------------

>16382_16382_44_CHD7-TCF7L2_CHD7_chr8_61655656_ENST00000524602_TCF7L2_chr10_114900943_ENST00000545257_length(amino acids)=1001AA_BP=565
MWFGGAVCWKKMADPGMMSLFGEDGNIFSEGLEGLGECGYPENPVNPMGQQMPIDQGFASLQPSLHHPSTNQNQTKLTHFDHYNQYEQQK
MHLMDQPNRMMSNTPGNGLASPHSQYHTPPVPQVPHGGSGGGQMGVYPGMQNERHGQSFVDSSSMWGPRAVQVPDQIRAPYQQQQPQPQP
PQPAPSGPPAQGHPQHMQQMGSYMARGDFSMQQHGQPQQRMSQFSQGQEGLNQGNPFIATSGPGHLSHVPQQSPSMAPSLRHSVQQFHHH
PSTALHGESVAHSPRFSPNPPQQGAVRPQTLNFSSRSQTVPSPTINNSGQYSRYPYSNLNQGLVNNTGMNQNLGLTNNTPMNQSVPRYPN
AVGFPSNSGQGLMHQQPIHPSGSLNQMNTQTMHPSQPQGTYASPPPMSPMKAMSNPAGTPPPQVRPGSAGIPMEVGSYPNMPHPQPSHQP
PGAMGIGQRNMGPRNMQQSRPFIGMSSAPRELTGHMRPNGCPGVGLGDPQAIQERLIPGQQHPGQQPSFQQLPTCPPLQPHPGLHHQSSP
PHPHHQPWAQLHPSPQNTPQKVPVHQSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPG
TVGQIPHPLGWLVPQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQD
SKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKK
RKRDKQPGETNEHSECFLNPCLSLPPITDANTPKKCRALFGLDRQTLWCKPCRRKKKCVRYIQGEGSCLSPPSSDGSLLDSPPPSPNLLG
SPPRDAKSQTEQTQPLSLSLKPDPLAHLSMMPPPPALLLAEATHKASALCPNGALDLPPAALQPAAPSSSIAQPSTSSLHSHSSLAGTQP

--------------------------------------------------------------

>16382_16382_45_CHD7-TCF7L2_CHD7_chr8_61655656_ENST00000525508_TCF7L2_chr10_114900942_ENST00000349937_length(amino acids)=659AA_BP=554
MADPGMMSLFGEDGNIFSEGLEGLGECGYPENPVNPMGQQMPIDQGFASLQPSLHHPSTNQNQTKLTHFDHYNQYEQQKMHLMDQPNRMM
SNTPGNGLASPHSQYHTPPVPQVPHGGSGGGQMGVYPGMQNERHGQSFVDSSSMWGPRAVQVPDQIRAPYQQQQPQPQPPQPAPSGPPAQ
GHPQHMQQMGSYMARGDFSMQQHGQPQQRMSQFSQGQEGLNQGNPFIATSGPGHLSHVPQQSPSMAPSLRHSVQQFHHHPSTALHGESVA
HSPRFSPNPPQQGAVRPQTLNFSSRSQTVPSPTINNSGQYSRYPYSNLNQGLVNNTGMNQNLGLTNNTPMNQSVPRYPNAVGFPSNSGQG
LMHQQPIHPSGSLNQMNTQTMHPSQPQGTYASPPPMSPMKAMSNPAGTPPPQVRPGSAGIPMEVGSYPNMPHPQPSHQPPGAMGIGQRNM
GPRNMQQSRPFIGMSSAPRELTGHMRPNGCPGVGLGDPQAIQERLIPGQQHPGQQPSFQQLPTCPPLQPHPGLHHQSSPPHPHHQPWAQL
HPSPQNTPQKVPVHQSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVGQIPHPLGW

--------------------------------------------------------------

>16382_16382_46_CHD7-TCF7L2_CHD7_chr8_61655656_ENST00000525508_TCF7L2_chr10_114900942_ENST00000352065_length(amino acids)=853AA_BP=554
MADPGMMSLFGEDGNIFSEGLEGLGECGYPENPVNPMGQQMPIDQGFASLQPSLHHPSTNQNQTKLTHFDHYNQYEQQKMHLMDQPNRMM
SNTPGNGLASPHSQYHTPPVPQVPHGGSGGGQMGVYPGMQNERHGQSFVDSSSMWGPRAVQVPDQIRAPYQQQQPQPQPPQPAPSGPPAQ
GHPQHMQQMGSYMARGDFSMQQHGQPQQRMSQFSQGQEGLNQGNPFIATSGPGHLSHVPQQSPSMAPSLRHSVQQFHHHPSTALHGESVA
HSPRFSPNPPQQGAVRPQTLNFSSRSQTVPSPTINNSGQYSRYPYSNLNQGLVNNTGMNQNLGLTNNTPMNQSVPRYPNAVGFPSNSGQG
LMHQQPIHPSGSLNQMNTQTMHPSQPQGTYASPPPMSPMKAMSNPAGTPPPQVRPGSAGIPMEVGSYPNMPHPQPSHQPPGAMGIGQRNM
GPRNMQQSRPFIGMSSAPRELTGHMRPNGCPGVGLGDPQAIQERLIPGQQHPGQQPSFQQLPTCPPLQPHPGLHHQSSPPHPHHQPWAQL
HPSPQNTPQKVPVHQSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVGQIPHPLGW
LVPQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQDSKKEEEKKKPH
IKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDKQPGETN

--------------------------------------------------------------

>16382_16382_47_CHD7-TCF7L2_CHD7_chr8_61655656_ENST00000525508_TCF7L2_chr10_114900942_ENST00000355717_length(amino acids)=836AA_BP=554
MADPGMMSLFGEDGNIFSEGLEGLGECGYPENPVNPMGQQMPIDQGFASLQPSLHHPSTNQNQTKLTHFDHYNQYEQQKMHLMDQPNRMM
SNTPGNGLASPHSQYHTPPVPQVPHGGSGGGQMGVYPGMQNERHGQSFVDSSSMWGPRAVQVPDQIRAPYQQQQPQPQPPQPAPSGPPAQ
GHPQHMQQMGSYMARGDFSMQQHGQPQQRMSQFSQGQEGLNQGNPFIATSGPGHLSHVPQQSPSMAPSLRHSVQQFHHHPSTALHGESVA
HSPRFSPNPPQQGAVRPQTLNFSSRSQTVPSPTINNSGQYSRYPYSNLNQGLVNNTGMNQNLGLTNNTPMNQSVPRYPNAVGFPSNSGQG
LMHQQPIHPSGSLNQMNTQTMHPSQPQGTYASPPPMSPMKAMSNPAGTPPPQVRPGSAGIPMEVGSYPNMPHPQPSHQPPGAMGIGQRNM
GPRNMQQSRPFIGMSSAPRELTGHMRPNGCPGVGLGDPQAIQERLIPGQQHPGQQPSFQQLPTCPPLQPHPGLHHQSSPPHPHHQPWAQL
HPSPQNTPQKVPVHQSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVGQIPHPLGW
LVPQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQDSKKEEEKKKPH
IKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDKQPGETN

--------------------------------------------------------------

>16382_16382_48_CHD7-TCF7L2_CHD7_chr8_61655656_ENST00000525508_TCF7L2_chr10_114900942_ENST00000355995_length(amino acids)=990AA_BP=554
MADPGMMSLFGEDGNIFSEGLEGLGECGYPENPVNPMGQQMPIDQGFASLQPSLHHPSTNQNQTKLTHFDHYNQYEQQKMHLMDQPNRMM
SNTPGNGLASPHSQYHTPPVPQVPHGGSGGGQMGVYPGMQNERHGQSFVDSSSMWGPRAVQVPDQIRAPYQQQQPQPQPPQPAPSGPPAQ
GHPQHMQQMGSYMARGDFSMQQHGQPQQRMSQFSQGQEGLNQGNPFIATSGPGHLSHVPQQSPSMAPSLRHSVQQFHHHPSTALHGESVA
HSPRFSPNPPQQGAVRPQTLNFSSRSQTVPSPTINNSGQYSRYPYSNLNQGLVNNTGMNQNLGLTNNTPMNQSVPRYPNAVGFPSNSGQG
LMHQQPIHPSGSLNQMNTQTMHPSQPQGTYASPPPMSPMKAMSNPAGTPPPQVRPGSAGIPMEVGSYPNMPHPQPSHQPPGAMGIGQRNM
GPRNMQQSRPFIGMSSAPRELTGHMRPNGCPGVGLGDPQAIQERLIPGQQHPGQQPSFQQLPTCPPLQPHPGLHHQSSPPHPHHQPWAQL
HPSPQNTPQKVPVHQSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVGQIPHPLGW
LVPQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQDSKKEEEKKKPH
IKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDKQPGETN
EHSECFLNPCLSLPPITDLSAPKKCRARFGLDQQNNWCGPCRRKKKCVRYIQGEGSCLSPPSSDGSLLDSPPPSPNLLGSPPRDAKSQTE
QTQPLSLSLKPDPLAHLSMMPPPPALLLAEATHKASALCPNGALDLPPAALQPAAPSSSIAQPSTSSLHSHSSLAGTQPQPLSLVTKSLE

--------------------------------------------------------------

>16382_16382_49_CHD7-TCF7L2_CHD7_chr8_61655656_ENST00000525508_TCF7L2_chr10_114900942_ENST00000369395_length(amino acids)=663AA_BP=554
MADPGMMSLFGEDGNIFSEGLEGLGECGYPENPVNPMGQQMPIDQGFASLQPSLHHPSTNQNQTKLTHFDHYNQYEQQKMHLMDQPNRMM
SNTPGNGLASPHSQYHTPPVPQVPHGGSGGGQMGVYPGMQNERHGQSFVDSSSMWGPRAVQVPDQIRAPYQQQQPQPQPPQPAPSGPPAQ
GHPQHMQQMGSYMARGDFSMQQHGQPQQRMSQFSQGQEGLNQGNPFIATSGPGHLSHVPQQSPSMAPSLRHSVQQFHHHPSTALHGESVA
HSPRFSPNPPQQGAVRPQTLNFSSRSQTVPSPTINNSGQYSRYPYSNLNQGLVNNTGMNQNLGLTNNTPMNQSVPRYPNAVGFPSNSGQG
LMHQQPIHPSGSLNQMNTQTMHPSQPQGTYASPPPMSPMKAMSNPAGTPPPQVRPGSAGIPMEVGSYPNMPHPQPSHQPPGAMGIGQRNM
GPRNMQQSRPFIGMSSAPRELTGHMRPNGCPGVGLGDPQAIQERLIPGQQHPGQQPSFQQLPTCPPLQPHPGLHHQSSPPHPHHQPWAQL
HPSPQNTPQKVPVHQSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVGQIPHPLGW

--------------------------------------------------------------

>16382_16382_50_CHD7-TCF7L2_CHD7_chr8_61655656_ENST00000525508_TCF7L2_chr10_114900942_ENST00000369397_length(amino acids)=990AA_BP=554
MADPGMMSLFGEDGNIFSEGLEGLGECGYPENPVNPMGQQMPIDQGFASLQPSLHHPSTNQNQTKLTHFDHYNQYEQQKMHLMDQPNRMM
SNTPGNGLASPHSQYHTPPVPQVPHGGSGGGQMGVYPGMQNERHGQSFVDSSSMWGPRAVQVPDQIRAPYQQQQPQPQPPQPAPSGPPAQ
GHPQHMQQMGSYMARGDFSMQQHGQPQQRMSQFSQGQEGLNQGNPFIATSGPGHLSHVPQQSPSMAPSLRHSVQQFHHHPSTALHGESVA
HSPRFSPNPPQQGAVRPQTLNFSSRSQTVPSPTINNSGQYSRYPYSNLNQGLVNNTGMNQNLGLTNNTPMNQSVPRYPNAVGFPSNSGQG
LMHQQPIHPSGSLNQMNTQTMHPSQPQGTYASPPPMSPMKAMSNPAGTPPPQVRPGSAGIPMEVGSYPNMPHPQPSHQPPGAMGIGQRNM
GPRNMQQSRPFIGMSSAPRELTGHMRPNGCPGVGLGDPQAIQERLIPGQQHPGQQPSFQQLPTCPPLQPHPGLHHQSSPPHPHHQPWAQL
HPSPQNTPQKVPVHQSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVGQIPHPLGW
LVPQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQDSKKEEEKKKPH
IKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDKQPGETN
EHSECFLNPCLSLPPITDLSAPKKCRARFGLDQQNNWCGPCRRKKKCVRYIQGEGSCLSPPSSDGSLLDSPPPSPNLLGSPPRDAKSQTE
QTQPLSLSLKPDPLAHLSMMPPPPALLLAEATHKASALCPNGALDLPPAALQPAAPSSSIAQPSTSSLHSHSSLAGTQPQPLSLVTKSLE

--------------------------------------------------------------

>16382_16382_51_CHD7-TCF7L2_CHD7_chr8_61655656_ENST00000525508_TCF7L2_chr10_114900942_ENST00000534894_length(amino acids)=865AA_BP=554
MADPGMMSLFGEDGNIFSEGLEGLGECGYPENPVNPMGQQMPIDQGFASLQPSLHHPSTNQNQTKLTHFDHYNQYEQQKMHLMDQPNRMM
SNTPGNGLASPHSQYHTPPVPQVPHGGSGGGQMGVYPGMQNERHGQSFVDSSSMWGPRAVQVPDQIRAPYQQQQPQPQPPQPAPSGPPAQ
GHPQHMQQMGSYMARGDFSMQQHGQPQQRMSQFSQGQEGLNQGNPFIATSGPGHLSHVPQQSPSMAPSLRHSVQQFHHHPSTALHGESVA
HSPRFSPNPPQQGAVRPQTLNFSSRSQTVPSPTINNSGQYSRYPYSNLNQGLVNNTGMNQNLGLTNNTPMNQSVPRYPNAVGFPSNSGQG
LMHQQPIHPSGSLNQMNTQTMHPSQPQGTYASPPPMSPMKAMSNPAGTPPPQVRPGSAGIPMEVGSYPNMPHPQPSHQPPGAMGIGQRNM
GPRNMQQSRPFIGMSSAPRELTGHMRPNGCPGVGLGDPQAIQERLIPGQQHPGQQPSFQQLPTCPPLQPHPGLHHQSSPPHPHHQPWAQL
HPSPQNTPQKVPVHQSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVGQIPHPLGW
LVPQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQDSKKEEEKKKPH
IKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDKQPGETN

--------------------------------------------------------------

>16382_16382_52_CHD7-TCF7L2_CHD7_chr8_61655656_ENST00000525508_TCF7L2_chr10_114900942_ENST00000536810_length(amino acids)=973AA_BP=554
MADPGMMSLFGEDGNIFSEGLEGLGECGYPENPVNPMGQQMPIDQGFASLQPSLHHPSTNQNQTKLTHFDHYNQYEQQKMHLMDQPNRMM
SNTPGNGLASPHSQYHTPPVPQVPHGGSGGGQMGVYPGMQNERHGQSFVDSSSMWGPRAVQVPDQIRAPYQQQQPQPQPPQPAPSGPPAQ
GHPQHMQQMGSYMARGDFSMQQHGQPQQRMSQFSQGQEGLNQGNPFIATSGPGHLSHVPQQSPSMAPSLRHSVQQFHHHPSTALHGESVA
HSPRFSPNPPQQGAVRPQTLNFSSRSQTVPSPTINNSGQYSRYPYSNLNQGLVNNTGMNQNLGLTNNTPMNQSVPRYPNAVGFPSNSGQG
LMHQQPIHPSGSLNQMNTQTMHPSQPQGTYASPPPMSPMKAMSNPAGTPPPQVRPGSAGIPMEVGSYPNMPHPQPSHQPPGAMGIGQRNM
GPRNMQQSRPFIGMSSAPRELTGHMRPNGCPGVGLGDPQAIQERLIPGQQHPGQQPSFQQLPTCPPLQPHPGLHHQSSPPHPHHQPWAQL
HPSPQNTPQKVPVHQSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVGQIPHPLGW
LVPQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQDSKKEEEKKKPH
IKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDKQPGETN
DLSAPKKCRARFGLDQQNNWCGPCRRKKKCVRYIQGEGSCLSPPSSDGSLLDSPPPSPNLLGSPPRDAKSQTEQTQPLSLSLKPDPLAHL

--------------------------------------------------------------

>16382_16382_53_CHD7-TCF7L2_CHD7_chr8_61655656_ENST00000525508_TCF7L2_chr10_114900942_ENST00000538897_length(amino acids)=853AA_BP=554
MADPGMMSLFGEDGNIFSEGLEGLGECGYPENPVNPMGQQMPIDQGFASLQPSLHHPSTNQNQTKLTHFDHYNQYEQQKMHLMDQPNRMM
SNTPGNGLASPHSQYHTPPVPQVPHGGSGGGQMGVYPGMQNERHGQSFVDSSSMWGPRAVQVPDQIRAPYQQQQPQPQPPQPAPSGPPAQ
GHPQHMQQMGSYMARGDFSMQQHGQPQQRMSQFSQGQEGLNQGNPFIATSGPGHLSHVPQQSPSMAPSLRHSVQQFHHHPSTALHGESVA
HSPRFSPNPPQQGAVRPQTLNFSSRSQTVPSPTINNSGQYSRYPYSNLNQGLVNNTGMNQNLGLTNNTPMNQSVPRYPNAVGFPSNSGQG
LMHQQPIHPSGSLNQMNTQTMHPSQPQGTYASPPPMSPMKAMSNPAGTPPPQVRPGSAGIPMEVGSYPNMPHPQPSHQPPGAMGIGQRNM
GPRNMQQSRPFIGMSSAPRELTGHMRPNGCPGVGLGDPQAIQERLIPGQQHPGQQPSFQQLPTCPPLQPHPGLHHQSSPPHPHHQPWAQL
HPSPQNTPQKVPVHQSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVGQIPHPLGW
LVPQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQDSKKEEEKKKPH
IKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDKQPGETN

--------------------------------------------------------------

>16382_16382_54_CHD7-TCF7L2_CHD7_chr8_61655656_ENST00000525508_TCF7L2_chr10_114900942_ENST00000543371_length(amino acids)=973AA_BP=554
MADPGMMSLFGEDGNIFSEGLEGLGECGYPENPVNPMGQQMPIDQGFASLQPSLHHPSTNQNQTKLTHFDHYNQYEQQKMHLMDQPNRMM
SNTPGNGLASPHSQYHTPPVPQVPHGGSGGGQMGVYPGMQNERHGQSFVDSSSMWGPRAVQVPDQIRAPYQQQQPQPQPPQPAPSGPPAQ
GHPQHMQQMGSYMARGDFSMQQHGQPQQRMSQFSQGQEGLNQGNPFIATSGPGHLSHVPQQSPSMAPSLRHSVQQFHHHPSTALHGESVA
HSPRFSPNPPQQGAVRPQTLNFSSRSQTVPSPTINNSGQYSRYPYSNLNQGLVNNTGMNQNLGLTNNTPMNQSVPRYPNAVGFPSNSGQG
LMHQQPIHPSGSLNQMNTQTMHPSQPQGTYASPPPMSPMKAMSNPAGTPPPQVRPGSAGIPMEVGSYPNMPHPQPSHQPPGAMGIGQRNM
GPRNMQQSRPFIGMSSAPRELTGHMRPNGCPGVGLGDPQAIQERLIPGQQHPGQQPSFQQLPTCPPLQPHPGLHHQSSPPHPHHQPWAQL
HPSPQNTPQKVPVHQSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVGQIPHPLGW
LVPQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQDSKKEEEKKKPH
IKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDKQPGETN
DANTPKKCRALFGLDRQTLWCKPCRRKKKCVRYIQGEGSCLSPPSSDGSLLDSPPPSPNLLGSPPRDAKSQTEQTQPLSLSLKPDPLAHL

--------------------------------------------------------------

>16382_16382_55_CHD7-TCF7L2_CHD7_chr8_61655656_ENST00000525508_TCF7L2_chr10_114900942_ENST00000545257_length(amino acids)=990AA_BP=554
MADPGMMSLFGEDGNIFSEGLEGLGECGYPENPVNPMGQQMPIDQGFASLQPSLHHPSTNQNQTKLTHFDHYNQYEQQKMHLMDQPNRMM
SNTPGNGLASPHSQYHTPPVPQVPHGGSGGGQMGVYPGMQNERHGQSFVDSSSMWGPRAVQVPDQIRAPYQQQQPQPQPPQPAPSGPPAQ
GHPQHMQQMGSYMARGDFSMQQHGQPQQRMSQFSQGQEGLNQGNPFIATSGPGHLSHVPQQSPSMAPSLRHSVQQFHHHPSTALHGESVA
HSPRFSPNPPQQGAVRPQTLNFSSRSQTVPSPTINNSGQYSRYPYSNLNQGLVNNTGMNQNLGLTNNTPMNQSVPRYPNAVGFPSNSGQG
LMHQQPIHPSGSLNQMNTQTMHPSQPQGTYASPPPMSPMKAMSNPAGTPPPQVRPGSAGIPMEVGSYPNMPHPQPSHQPPGAMGIGQRNM
GPRNMQQSRPFIGMSSAPRELTGHMRPNGCPGVGLGDPQAIQERLIPGQQHPGQQPSFQQLPTCPPLQPHPGLHHQSSPPHPHHQPWAQL
HPSPQNTPQKVPVHQSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVGQIPHPLGW
LVPQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQDSKKEEEKKKPH
IKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDKQPGETN
EHSECFLNPCLSLPPITDANTPKKCRALFGLDRQTLWCKPCRRKKKCVRYIQGEGSCLSPPSSDGSLLDSPPPSPNLLGSPPRDAKSQTE
QTQPLSLSLKPDPLAHLSMMPPPPALLLAEATHKASALCPNGALDLPPAALQPAAPSSSIAQPSTSSLHSHSSLAGTQPQPLSLVTKSLE

--------------------------------------------------------------

>16382_16382_56_CHD7-TCF7L2_CHD7_chr8_61655656_ENST00000525508_TCF7L2_chr10_114900943_ENST00000349937_length(amino acids)=659AA_BP=554
MADPGMMSLFGEDGNIFSEGLEGLGECGYPENPVNPMGQQMPIDQGFASLQPSLHHPSTNQNQTKLTHFDHYNQYEQQKMHLMDQPNRMM
SNTPGNGLASPHSQYHTPPVPQVPHGGSGGGQMGVYPGMQNERHGQSFVDSSSMWGPRAVQVPDQIRAPYQQQQPQPQPPQPAPSGPPAQ
GHPQHMQQMGSYMARGDFSMQQHGQPQQRMSQFSQGQEGLNQGNPFIATSGPGHLSHVPQQSPSMAPSLRHSVQQFHHHPSTALHGESVA
HSPRFSPNPPQQGAVRPQTLNFSSRSQTVPSPTINNSGQYSRYPYSNLNQGLVNNTGMNQNLGLTNNTPMNQSVPRYPNAVGFPSNSGQG
LMHQQPIHPSGSLNQMNTQTMHPSQPQGTYASPPPMSPMKAMSNPAGTPPPQVRPGSAGIPMEVGSYPNMPHPQPSHQPPGAMGIGQRNM
GPRNMQQSRPFIGMSSAPRELTGHMRPNGCPGVGLGDPQAIQERLIPGQQHPGQQPSFQQLPTCPPLQPHPGLHHQSSPPHPHHQPWAQL
HPSPQNTPQKVPVHQSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVGQIPHPLGW

--------------------------------------------------------------

>16382_16382_57_CHD7-TCF7L2_CHD7_chr8_61655656_ENST00000525508_TCF7L2_chr10_114900943_ENST00000352065_length(amino acids)=853AA_BP=554
MADPGMMSLFGEDGNIFSEGLEGLGECGYPENPVNPMGQQMPIDQGFASLQPSLHHPSTNQNQTKLTHFDHYNQYEQQKMHLMDQPNRMM
SNTPGNGLASPHSQYHTPPVPQVPHGGSGGGQMGVYPGMQNERHGQSFVDSSSMWGPRAVQVPDQIRAPYQQQQPQPQPPQPAPSGPPAQ
GHPQHMQQMGSYMARGDFSMQQHGQPQQRMSQFSQGQEGLNQGNPFIATSGPGHLSHVPQQSPSMAPSLRHSVQQFHHHPSTALHGESVA
HSPRFSPNPPQQGAVRPQTLNFSSRSQTVPSPTINNSGQYSRYPYSNLNQGLVNNTGMNQNLGLTNNTPMNQSVPRYPNAVGFPSNSGQG
LMHQQPIHPSGSLNQMNTQTMHPSQPQGTYASPPPMSPMKAMSNPAGTPPPQVRPGSAGIPMEVGSYPNMPHPQPSHQPPGAMGIGQRNM
GPRNMQQSRPFIGMSSAPRELTGHMRPNGCPGVGLGDPQAIQERLIPGQQHPGQQPSFQQLPTCPPLQPHPGLHHQSSPPHPHHQPWAQL
HPSPQNTPQKVPVHQSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVGQIPHPLGW
LVPQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQDSKKEEEKKKPH
IKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDKQPGETN

--------------------------------------------------------------

>16382_16382_58_CHD7-TCF7L2_CHD7_chr8_61655656_ENST00000525508_TCF7L2_chr10_114900943_ENST00000355717_length(amino acids)=836AA_BP=554
MADPGMMSLFGEDGNIFSEGLEGLGECGYPENPVNPMGQQMPIDQGFASLQPSLHHPSTNQNQTKLTHFDHYNQYEQQKMHLMDQPNRMM
SNTPGNGLASPHSQYHTPPVPQVPHGGSGGGQMGVYPGMQNERHGQSFVDSSSMWGPRAVQVPDQIRAPYQQQQPQPQPPQPAPSGPPAQ
GHPQHMQQMGSYMARGDFSMQQHGQPQQRMSQFSQGQEGLNQGNPFIATSGPGHLSHVPQQSPSMAPSLRHSVQQFHHHPSTALHGESVA
HSPRFSPNPPQQGAVRPQTLNFSSRSQTVPSPTINNSGQYSRYPYSNLNQGLVNNTGMNQNLGLTNNTPMNQSVPRYPNAVGFPSNSGQG
LMHQQPIHPSGSLNQMNTQTMHPSQPQGTYASPPPMSPMKAMSNPAGTPPPQVRPGSAGIPMEVGSYPNMPHPQPSHQPPGAMGIGQRNM
GPRNMQQSRPFIGMSSAPRELTGHMRPNGCPGVGLGDPQAIQERLIPGQQHPGQQPSFQQLPTCPPLQPHPGLHHQSSPPHPHHQPWAQL
HPSPQNTPQKVPVHQSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVGQIPHPLGW
LVPQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQDSKKEEEKKKPH
IKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDKQPGETN

--------------------------------------------------------------

>16382_16382_59_CHD7-TCF7L2_CHD7_chr8_61655656_ENST00000525508_TCF7L2_chr10_114900943_ENST00000355995_length(amino acids)=990AA_BP=554
MADPGMMSLFGEDGNIFSEGLEGLGECGYPENPVNPMGQQMPIDQGFASLQPSLHHPSTNQNQTKLTHFDHYNQYEQQKMHLMDQPNRMM
SNTPGNGLASPHSQYHTPPVPQVPHGGSGGGQMGVYPGMQNERHGQSFVDSSSMWGPRAVQVPDQIRAPYQQQQPQPQPPQPAPSGPPAQ
GHPQHMQQMGSYMARGDFSMQQHGQPQQRMSQFSQGQEGLNQGNPFIATSGPGHLSHVPQQSPSMAPSLRHSVQQFHHHPSTALHGESVA
HSPRFSPNPPQQGAVRPQTLNFSSRSQTVPSPTINNSGQYSRYPYSNLNQGLVNNTGMNQNLGLTNNTPMNQSVPRYPNAVGFPSNSGQG
LMHQQPIHPSGSLNQMNTQTMHPSQPQGTYASPPPMSPMKAMSNPAGTPPPQVRPGSAGIPMEVGSYPNMPHPQPSHQPPGAMGIGQRNM
GPRNMQQSRPFIGMSSAPRELTGHMRPNGCPGVGLGDPQAIQERLIPGQQHPGQQPSFQQLPTCPPLQPHPGLHHQSSPPHPHHQPWAQL
HPSPQNTPQKVPVHQSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVGQIPHPLGW
LVPQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQDSKKEEEKKKPH
IKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDKQPGETN
EHSECFLNPCLSLPPITDLSAPKKCRARFGLDQQNNWCGPCRRKKKCVRYIQGEGSCLSPPSSDGSLLDSPPPSPNLLGSPPRDAKSQTE
QTQPLSLSLKPDPLAHLSMMPPPPALLLAEATHKASALCPNGALDLPPAALQPAAPSSSIAQPSTSSLHSHSSLAGTQPQPLSLVTKSLE

--------------------------------------------------------------

>16382_16382_60_CHD7-TCF7L2_CHD7_chr8_61655656_ENST00000525508_TCF7L2_chr10_114900943_ENST00000369395_length(amino acids)=663AA_BP=554
MADPGMMSLFGEDGNIFSEGLEGLGECGYPENPVNPMGQQMPIDQGFASLQPSLHHPSTNQNQTKLTHFDHYNQYEQQKMHLMDQPNRMM
SNTPGNGLASPHSQYHTPPVPQVPHGGSGGGQMGVYPGMQNERHGQSFVDSSSMWGPRAVQVPDQIRAPYQQQQPQPQPPQPAPSGPPAQ
GHPQHMQQMGSYMARGDFSMQQHGQPQQRMSQFSQGQEGLNQGNPFIATSGPGHLSHVPQQSPSMAPSLRHSVQQFHHHPSTALHGESVA
HSPRFSPNPPQQGAVRPQTLNFSSRSQTVPSPTINNSGQYSRYPYSNLNQGLVNNTGMNQNLGLTNNTPMNQSVPRYPNAVGFPSNSGQG
LMHQQPIHPSGSLNQMNTQTMHPSQPQGTYASPPPMSPMKAMSNPAGTPPPQVRPGSAGIPMEVGSYPNMPHPQPSHQPPGAMGIGQRNM
GPRNMQQSRPFIGMSSAPRELTGHMRPNGCPGVGLGDPQAIQERLIPGQQHPGQQPSFQQLPTCPPLQPHPGLHHQSSPPHPHHQPWAQL
HPSPQNTPQKVPVHQSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVGQIPHPLGW

--------------------------------------------------------------

>16382_16382_61_CHD7-TCF7L2_CHD7_chr8_61655656_ENST00000525508_TCF7L2_chr10_114900943_ENST00000369397_length(amino acids)=990AA_BP=554
MADPGMMSLFGEDGNIFSEGLEGLGECGYPENPVNPMGQQMPIDQGFASLQPSLHHPSTNQNQTKLTHFDHYNQYEQQKMHLMDQPNRMM
SNTPGNGLASPHSQYHTPPVPQVPHGGSGGGQMGVYPGMQNERHGQSFVDSSSMWGPRAVQVPDQIRAPYQQQQPQPQPPQPAPSGPPAQ
GHPQHMQQMGSYMARGDFSMQQHGQPQQRMSQFSQGQEGLNQGNPFIATSGPGHLSHVPQQSPSMAPSLRHSVQQFHHHPSTALHGESVA
HSPRFSPNPPQQGAVRPQTLNFSSRSQTVPSPTINNSGQYSRYPYSNLNQGLVNNTGMNQNLGLTNNTPMNQSVPRYPNAVGFPSNSGQG
LMHQQPIHPSGSLNQMNTQTMHPSQPQGTYASPPPMSPMKAMSNPAGTPPPQVRPGSAGIPMEVGSYPNMPHPQPSHQPPGAMGIGQRNM
GPRNMQQSRPFIGMSSAPRELTGHMRPNGCPGVGLGDPQAIQERLIPGQQHPGQQPSFQQLPTCPPLQPHPGLHHQSSPPHPHHQPWAQL
HPSPQNTPQKVPVHQSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVGQIPHPLGW
LVPQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQDSKKEEEKKKPH
IKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDKQPGETN
EHSECFLNPCLSLPPITDLSAPKKCRARFGLDQQNNWCGPCRRKKKCVRYIQGEGSCLSPPSSDGSLLDSPPPSPNLLGSPPRDAKSQTE
QTQPLSLSLKPDPLAHLSMMPPPPALLLAEATHKASALCPNGALDLPPAALQPAAPSSSIAQPSTSSLHSHSSLAGTQPQPLSLVTKSLE

--------------------------------------------------------------

>16382_16382_62_CHD7-TCF7L2_CHD7_chr8_61655656_ENST00000525508_TCF7L2_chr10_114900943_ENST00000534894_length(amino acids)=865AA_BP=554
MADPGMMSLFGEDGNIFSEGLEGLGECGYPENPVNPMGQQMPIDQGFASLQPSLHHPSTNQNQTKLTHFDHYNQYEQQKMHLMDQPNRMM
SNTPGNGLASPHSQYHTPPVPQVPHGGSGGGQMGVYPGMQNERHGQSFVDSSSMWGPRAVQVPDQIRAPYQQQQPQPQPPQPAPSGPPAQ
GHPQHMQQMGSYMARGDFSMQQHGQPQQRMSQFSQGQEGLNQGNPFIATSGPGHLSHVPQQSPSMAPSLRHSVQQFHHHPSTALHGESVA
HSPRFSPNPPQQGAVRPQTLNFSSRSQTVPSPTINNSGQYSRYPYSNLNQGLVNNTGMNQNLGLTNNTPMNQSVPRYPNAVGFPSNSGQG
LMHQQPIHPSGSLNQMNTQTMHPSQPQGTYASPPPMSPMKAMSNPAGTPPPQVRPGSAGIPMEVGSYPNMPHPQPSHQPPGAMGIGQRNM
GPRNMQQSRPFIGMSSAPRELTGHMRPNGCPGVGLGDPQAIQERLIPGQQHPGQQPSFQQLPTCPPLQPHPGLHHQSSPPHPHHQPWAQL
HPSPQNTPQKVPVHQSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVGQIPHPLGW
LVPQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQDSKKEEEKKKPH
IKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDKQPGETN

--------------------------------------------------------------

>16382_16382_63_CHD7-TCF7L2_CHD7_chr8_61655656_ENST00000525508_TCF7L2_chr10_114900943_ENST00000536810_length(amino acids)=973AA_BP=554
MADPGMMSLFGEDGNIFSEGLEGLGECGYPENPVNPMGQQMPIDQGFASLQPSLHHPSTNQNQTKLTHFDHYNQYEQQKMHLMDQPNRMM
SNTPGNGLASPHSQYHTPPVPQVPHGGSGGGQMGVYPGMQNERHGQSFVDSSSMWGPRAVQVPDQIRAPYQQQQPQPQPPQPAPSGPPAQ
GHPQHMQQMGSYMARGDFSMQQHGQPQQRMSQFSQGQEGLNQGNPFIATSGPGHLSHVPQQSPSMAPSLRHSVQQFHHHPSTALHGESVA
HSPRFSPNPPQQGAVRPQTLNFSSRSQTVPSPTINNSGQYSRYPYSNLNQGLVNNTGMNQNLGLTNNTPMNQSVPRYPNAVGFPSNSGQG
LMHQQPIHPSGSLNQMNTQTMHPSQPQGTYASPPPMSPMKAMSNPAGTPPPQVRPGSAGIPMEVGSYPNMPHPQPSHQPPGAMGIGQRNM
GPRNMQQSRPFIGMSSAPRELTGHMRPNGCPGVGLGDPQAIQERLIPGQQHPGQQPSFQQLPTCPPLQPHPGLHHQSSPPHPHHQPWAQL
HPSPQNTPQKVPVHQSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVGQIPHPLGW
LVPQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQDSKKEEEKKKPH
IKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDKQPGETN
DLSAPKKCRARFGLDQQNNWCGPCRRKKKCVRYIQGEGSCLSPPSSDGSLLDSPPPSPNLLGSPPRDAKSQTEQTQPLSLSLKPDPLAHL

--------------------------------------------------------------

>16382_16382_64_CHD7-TCF7L2_CHD7_chr8_61655656_ENST00000525508_TCF7L2_chr10_114900943_ENST00000538897_length(amino acids)=853AA_BP=554
MADPGMMSLFGEDGNIFSEGLEGLGECGYPENPVNPMGQQMPIDQGFASLQPSLHHPSTNQNQTKLTHFDHYNQYEQQKMHLMDQPNRMM
SNTPGNGLASPHSQYHTPPVPQVPHGGSGGGQMGVYPGMQNERHGQSFVDSSSMWGPRAVQVPDQIRAPYQQQQPQPQPPQPAPSGPPAQ
GHPQHMQQMGSYMARGDFSMQQHGQPQQRMSQFSQGQEGLNQGNPFIATSGPGHLSHVPQQSPSMAPSLRHSVQQFHHHPSTALHGESVA
HSPRFSPNPPQQGAVRPQTLNFSSRSQTVPSPTINNSGQYSRYPYSNLNQGLVNNTGMNQNLGLTNNTPMNQSVPRYPNAVGFPSNSGQG
LMHQQPIHPSGSLNQMNTQTMHPSQPQGTYASPPPMSPMKAMSNPAGTPPPQVRPGSAGIPMEVGSYPNMPHPQPSHQPPGAMGIGQRNM
GPRNMQQSRPFIGMSSAPRELTGHMRPNGCPGVGLGDPQAIQERLIPGQQHPGQQPSFQQLPTCPPLQPHPGLHHQSSPPHPHHQPWAQL
HPSPQNTPQKVPVHQSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVGQIPHPLGW
LVPQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQDSKKEEEKKKPH
IKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDKQPGETN

--------------------------------------------------------------

>16382_16382_65_CHD7-TCF7L2_CHD7_chr8_61655656_ENST00000525508_TCF7L2_chr10_114900943_ENST00000543371_length(amino acids)=973AA_BP=554
MADPGMMSLFGEDGNIFSEGLEGLGECGYPENPVNPMGQQMPIDQGFASLQPSLHHPSTNQNQTKLTHFDHYNQYEQQKMHLMDQPNRMM
SNTPGNGLASPHSQYHTPPVPQVPHGGSGGGQMGVYPGMQNERHGQSFVDSSSMWGPRAVQVPDQIRAPYQQQQPQPQPPQPAPSGPPAQ
GHPQHMQQMGSYMARGDFSMQQHGQPQQRMSQFSQGQEGLNQGNPFIATSGPGHLSHVPQQSPSMAPSLRHSVQQFHHHPSTALHGESVA
HSPRFSPNPPQQGAVRPQTLNFSSRSQTVPSPTINNSGQYSRYPYSNLNQGLVNNTGMNQNLGLTNNTPMNQSVPRYPNAVGFPSNSGQG
LMHQQPIHPSGSLNQMNTQTMHPSQPQGTYASPPPMSPMKAMSNPAGTPPPQVRPGSAGIPMEVGSYPNMPHPQPSHQPPGAMGIGQRNM
GPRNMQQSRPFIGMSSAPRELTGHMRPNGCPGVGLGDPQAIQERLIPGQQHPGQQPSFQQLPTCPPLQPHPGLHHQSSPPHPHHQPWAQL
HPSPQNTPQKVPVHQSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVGQIPHPLGW
LVPQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQDSKKEEEKKKPH
IKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDKQPGETN
DANTPKKCRALFGLDRQTLWCKPCRRKKKCVRYIQGEGSCLSPPSSDGSLLDSPPPSPNLLGSPPRDAKSQTEQTQPLSLSLKPDPLAHL

--------------------------------------------------------------

>16382_16382_66_CHD7-TCF7L2_CHD7_chr8_61655656_ENST00000525508_TCF7L2_chr10_114900943_ENST00000545257_length(amino acids)=990AA_BP=554
MADPGMMSLFGEDGNIFSEGLEGLGECGYPENPVNPMGQQMPIDQGFASLQPSLHHPSTNQNQTKLTHFDHYNQYEQQKMHLMDQPNRMM
SNTPGNGLASPHSQYHTPPVPQVPHGGSGGGQMGVYPGMQNERHGQSFVDSSSMWGPRAVQVPDQIRAPYQQQQPQPQPPQPAPSGPPAQ
GHPQHMQQMGSYMARGDFSMQQHGQPQQRMSQFSQGQEGLNQGNPFIATSGPGHLSHVPQQSPSMAPSLRHSVQQFHHHPSTALHGESVA
HSPRFSPNPPQQGAVRPQTLNFSSRSQTVPSPTINNSGQYSRYPYSNLNQGLVNNTGMNQNLGLTNNTPMNQSVPRYPNAVGFPSNSGQG
LMHQQPIHPSGSLNQMNTQTMHPSQPQGTYASPPPMSPMKAMSNPAGTPPPQVRPGSAGIPMEVGSYPNMPHPQPSHQPPGAMGIGQRNM
GPRNMQQSRPFIGMSSAPRELTGHMRPNGCPGVGLGDPQAIQERLIPGQQHPGQQPSFQQLPTCPPLQPHPGLHHQSSPPHPHHQPWAQL
HPSPQNTPQKVPVHQSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVGQIPHPLGW
LVPQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQDSKKEEEKKKPH
IKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDKQPGETN
EHSECFLNPCLSLPPITDANTPKKCRALFGLDRQTLWCKPCRRKKKCVRYIQGEGSCLSPPSSDGSLLDSPPPSPNLLGSPPRDAKSQTE
QTQPLSLSLKPDPLAHLSMMPPPPALLLAEATHKASALCPNGALDLPPAALQPAAPSSSIAQPSTSSLHSHSSLAGTQPQPLSLVTKSLE

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Fusion Protein Functional Features

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr8:61655656/chr10:114900943)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
CHD7 Q9P2D1	TCF7L2 Q9NQB0
FUNCTION: Probable transcription regulator. Maybe involved in the in 45S precursor rRNA production. {ECO:0000269\|PubMed:22646239}.	FUNCTION: Participates in the Wnt signaling pathway and modulates MYC expression by binding to its promoter in a sequence-specific manner. Acts as repressor in the absence of CTNNB1, and as activator in its presence. Activates transcription from promoters with several copies of the Tcf motif 5'-CCTTTGATC-3' in the presence of CTNNB1. TLE1, TLE2, TLE3 and TLE4 repress transactivation mediated by TCF7L2/TCF4 and CTNNB1. Expression of dominant-negative mutants results in cell-cycle arrest in G1. Necessary for the maintenance of the epithelial stem-cell compartment of the small intestine. {ECO:0000269\|PubMed:12408868, ECO:0000269\|PubMed:12727872, ECO:0000269\|PubMed:19443654, ECO:0000269\|PubMed:22699938, ECO:0000269\|PubMed:9727977}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page
* Minus value of BPloci means that the break pointn is located before the CDS.

- Retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

CHD7

chr8:61655656

chr10:114900942

ENST00000423902

151_222

555.0

2998.0

Compositional bias

Note=Gln-rich

Hgene

CHD7

chr8:61655656

chr10:114900942

ENST00000524602

151_222

555.0

949.0

Compositional bias

Note=Gln-rich

Hgene

CHD7

chr8:61655656

chr10:114900942

ENST00000525508

151_222

555.0

1139.0

Compositional bias

Note=Gln-rich

Hgene

CHD7

chr8:61655656

chr10:114900943

ENST00000423902

151_222

555.0

2998.0

Compositional bias

Note=Gln-rich

Hgene

CHD7

chr8:61655656

chr10:114900943

ENST00000524602

151_222

555.0

949.0

Compositional bias

Note=Gln-rich

Hgene

CHD7

chr8:61655656

chr10:114900943

ENST00000525508

151_222

555.0

1139.0

Compositional bias

Note=Gln-rich

Tgene

TCF7L2

chr8:61655656

chr10:114900942

ENST00000352065

178_317

161.0

386.0

Compositional bias

Note=Pro-rich

Tgene

TCF7L2

chr8:61655656

chr10:114900942

ENST00000369397

178_317

161.0

597.0

Compositional bias

Note=Pro-rich

Tgene

TCF7L2

chr8:61655656

chr10:114900943

ENST00000352065

178_317

161.0

386.0

Compositional bias

Note=Pro-rich

Tgene

TCF7L2

chr8:61655656

chr10:114900943

ENST00000369397

178_317

161.0

597.0

Compositional bias

Note=Pro-rich

Tgene

TCF7L2

chr8:61655656

chr10:114900942

ENST00000352065

350_418

161.0

386.0

DNA binding

HMG box

Tgene

TCF7L2

chr8:61655656

chr10:114900942

ENST00000355717

350_418

208.0

490.0

DNA binding

HMG box

Tgene

TCF7L2

chr8:61655656

chr10:114900942

ENST00000355995

350_418

184.0

620.0

DNA binding

HMG box

Tgene

TCF7L2

chr8:61655656

chr10:114900942

ENST00000369397

350_418

161.0

597.0

DNA binding

HMG box

Tgene

TCF7L2

chr8:61655656

chr10:114900942

ENST00000534894

350_418

184.0

495.0

DNA binding

HMG box

Tgene

TCF7L2

chr8:61655656

chr10:114900942

ENST00000536810

350_418

184.0

603.0

DNA binding

HMG box

Tgene

TCF7L2

chr8:61655656

chr10:114900942

ENST00000538897

350_418

184.0

483.0

DNA binding

HMG box

Tgene

TCF7L2

chr8:61655656

chr10:114900942

ENST00000543371

350_418

184.0

603.0

DNA binding

HMG box

Tgene

TCF7L2

chr8:61655656

chr10:114900942

ENST00000545257

350_418

184.0

620.0

DNA binding

HMG box

Tgene

TCF7L2

chr8:61655656

chr10:114900943

ENST00000352065

350_418

161.0

386.0

DNA binding

HMG box

Tgene

TCF7L2

chr8:61655656

chr10:114900943

ENST00000355717

350_418

208.0

490.0

DNA binding

HMG box

Tgene

TCF7L2

chr8:61655656

chr10:114900943

ENST00000355995

350_418

184.0

620.0

DNA binding

HMG box

Tgene

TCF7L2

chr8:61655656

chr10:114900943

ENST00000369397

350_418

161.0

597.0

DNA binding

HMG box

Tgene

TCF7L2

chr8:61655656

chr10:114900943

ENST00000534894

350_418

184.0

495.0

DNA binding

HMG box

Tgene

TCF7L2

chr8:61655656

chr10:114900943

ENST00000536810

350_418

184.0

603.0

DNA binding

HMG box

Tgene

TCF7L2

chr8:61655656

chr10:114900943

ENST00000538897

350_418

184.0

483.0

DNA binding

HMG box

Tgene

TCF7L2

chr8:61655656

chr10:114900943

ENST00000543371

350_418

184.0

603.0

DNA binding

HMG box

Tgene

TCF7L2

chr8:61655656

chr10:114900943

ENST00000545257

350_418

184.0

620.0

DNA binding

HMG box

Tgene

TCF7L2

chr8:61655656

chr10:114900942

ENST00000352065

425_430

161.0

386.0

Motif

Nuclear localization signal

Tgene

TCF7L2

chr8:61655656

chr10:114900942

ENST00000355717

425_430

208.0

490.0

Motif

Nuclear localization signal

Tgene

TCF7L2

chr8:61655656

chr10:114900942

ENST00000355995

425_430

184.0

620.0

Motif

Nuclear localization signal

Tgene

TCF7L2

chr8:61655656

chr10:114900942

ENST00000369397

425_430

161.0

597.0

Motif

Nuclear localization signal

Tgene

TCF7L2

chr8:61655656

chr10:114900942

ENST00000534894

425_430

184.0

495.0

Motif

Nuclear localization signal

Tgene

TCF7L2

chr8:61655656

chr10:114900942

ENST00000536810

425_430

184.0

603.0

Motif

Nuclear localization signal

Tgene

TCF7L2

chr8:61655656

chr10:114900942

ENST00000538897

425_430

184.0

483.0

Motif

Nuclear localization signal

Tgene

TCF7L2

chr8:61655656

chr10:114900942

ENST00000543371

425_430

184.0

603.0

Motif

Nuclear localization signal

Tgene

TCF7L2

chr8:61655656

chr10:114900942

ENST00000545257

425_430

184.0

620.0

Motif

Nuclear localization signal

Tgene

TCF7L2

chr8:61655656

chr10:114900943

ENST00000352065

425_430

161.0

386.0

Motif

Nuclear localization signal

Tgene

TCF7L2

chr8:61655656

chr10:114900943

ENST00000355717

425_430

208.0

490.0

Motif

Nuclear localization signal

Tgene

TCF7L2

chr8:61655656

chr10:114900943

ENST00000355995

425_430

184.0

620.0

Motif

Nuclear localization signal

Tgene

TCF7L2

chr8:61655656

chr10:114900943

ENST00000369397

425_430

161.0

597.0

Motif

Nuclear localization signal

Tgene

TCF7L2

chr8:61655656

chr10:114900943

ENST00000534894

425_430

184.0

495.0

Motif

Nuclear localization signal

Tgene

TCF7L2

chr8:61655656

chr10:114900943

ENST00000536810

425_430

184.0

603.0

Motif

Nuclear localization signal

Tgene

TCF7L2

chr8:61655656

chr10:114900943

ENST00000538897

425_430

184.0

483.0

Motif

Nuclear localization signal

Tgene

TCF7L2

chr8:61655656

chr10:114900943

ENST00000543371

425_430

184.0

603.0

Motif

Nuclear localization signal

Tgene

TCF7L2

chr8:61655656

chr10:114900943

ENST00000545257

425_430

184.0

620.0

Motif

Nuclear localization signal

Tgene

TCF7L2

chr8:61655656

chr10:114900942

ENST00000352065

459_505

161.0

386.0

Region

Note=Promoter-specific activation domain

Tgene

TCF7L2

chr8:61655656

chr10:114900942

ENST00000355717

459_505

208.0

490.0

Region

Note=Promoter-specific activation domain

Tgene

TCF7L2

chr8:61655656

chr10:114900942

ENST00000355995

459_505

184.0

620.0

Region

Note=Promoter-specific activation domain

Tgene

TCF7L2

chr8:61655656

chr10:114900942

ENST00000369397

459_505

161.0

597.0

Region

Note=Promoter-specific activation domain

Tgene

TCF7L2

chr8:61655656

chr10:114900942

ENST00000534894

459_505

184.0

495.0

Region

Note=Promoter-specific activation domain

Tgene

TCF7L2

chr8:61655656

chr10:114900942

ENST00000536810

459_505

184.0

603.0

Region

Note=Promoter-specific activation domain

Tgene

TCF7L2

chr8:61655656

chr10:114900942

ENST00000538897

459_505

184.0

483.0

Region

Note=Promoter-specific activation domain

Tgene

TCF7L2

chr8:61655656

chr10:114900942

ENST00000543371

459_505

184.0

603.0

Region

Note=Promoter-specific activation domain

Tgene

TCF7L2

chr8:61655656

chr10:114900942

ENST00000545257

459_505

184.0

620.0

Region

Note=Promoter-specific activation domain

Tgene

TCF7L2

chr8:61655656

chr10:114900943

ENST00000352065

459_505

161.0

386.0

Region

Note=Promoter-specific activation domain

Tgene

TCF7L2

chr8:61655656

chr10:114900943

ENST00000355717

459_505

208.0

490.0

Region

Note=Promoter-specific activation domain

Tgene

TCF7L2

chr8:61655656

chr10:114900943

ENST00000355995

459_505

184.0

620.0

Region

Note=Promoter-specific activation domain

Tgene

TCF7L2

chr8:61655656

chr10:114900943

ENST00000369397

459_505

161.0

597.0

Region

Note=Promoter-specific activation domain

Tgene

TCF7L2

chr8:61655656

chr10:114900943

ENST00000534894

459_505

184.0

495.0

Region

Note=Promoter-specific activation domain

Tgene

TCF7L2

chr8:61655656

chr10:114900943

ENST00000536810

459_505

184.0

603.0

Region

Note=Promoter-specific activation domain

Tgene

TCF7L2

chr8:61655656

chr10:114900943

ENST00000538897

459_505

184.0

483.0

Region

Note=Promoter-specific activation domain

Tgene

TCF7L2

chr8:61655656

chr10:114900943

ENST00000543371

459_505

184.0

603.0

Region

Note=Promoter-specific activation domain

Tgene

TCF7L2

chr8:61655656

chr10:114900943

ENST00000545257

459_505

184.0

620.0

Region

Note=Promoter-specific activation domain

- Not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

CHD7

chr8:61655656

chr10:114900942

ENST00000423902

2401_2431

555.0

2998.0

Coiled coil

Ontology_term=ECO:0000255

Hgene

CHD7

chr8:61655656

chr10:114900942

ENST00000524602

2401_2431

555.0

949.0

Coiled coil

Ontology_term=ECO:0000255

Hgene

CHD7

chr8:61655656

chr10:114900942

ENST00000525508

2401_2431

555.0

1139.0

Coiled coil

Ontology_term=ECO:0000255

Hgene

CHD7

chr8:61655656

chr10:114900943

ENST00000423902

2401_2431

555.0

2998.0

Coiled coil

Ontology_term=ECO:0000255

Hgene

CHD7

chr8:61655656

chr10:114900943

ENST00000524602

2401_2431

555.0

949.0

Coiled coil

Ontology_term=ECO:0000255

Hgene

CHD7

chr8:61655656

chr10:114900943

ENST00000525508

2401_2431

555.0

1139.0

Coiled coil

Ontology_term=ECO:0000255

Hgene

CHD7

chr8:61655656

chr10:114900942

ENST00000423902

1939_1945

555.0

2998.0

Compositional bias

Note=Poly-Arg

Hgene

CHD7

chr8:61655656

chr10:114900942

ENST00000423902

2165_2258

555.0

2998.0

Compositional bias

Note=Glu-rich

Hgene

CHD7

chr8:61655656

chr10:114900942

ENST00000423902

2398_2405

555.0

2998.0

Compositional bias

Note=Poly-Arg

Hgene

CHD7

chr8:61655656

chr10:114900942

ENST00000423902

2726_2736

555.0

2998.0

Compositional bias

Note=Poly-Ala

Hgene

CHD7

chr8:61655656

chr10:114900942

ENST00000423902

383_568

555.0

2998.0

Compositional bias

Note=Pro-rich

Hgene

CHD7

chr8:61655656

chr10:114900942

ENST00000423902

597_718

555.0

2998.0

Compositional bias

Note=Lys-rich

Hgene

CHD7

chr8:61655656

chr10:114900942

ENST00000524602

1939_1945

555.0

949.0

Compositional bias

Note=Poly-Arg

Hgene

CHD7

chr8:61655656

chr10:114900942

ENST00000524602

2165_2258

555.0

949.0

Compositional bias

Note=Glu-rich

Hgene

CHD7

chr8:61655656

chr10:114900942

ENST00000524602

2398_2405

555.0

949.0

Compositional bias

Note=Poly-Arg

Hgene

CHD7

chr8:61655656

chr10:114900942

ENST00000524602

2726_2736

555.0

949.0

Compositional bias

Note=Poly-Ala

Hgene

CHD7

chr8:61655656

chr10:114900942

ENST00000524602

383_568

555.0

949.0

Compositional bias

Note=Pro-rich

Hgene

CHD7

chr8:61655656

chr10:114900942

ENST00000524602

597_718

555.0

949.0

Compositional bias

Note=Lys-rich

Hgene

CHD7

chr8:61655656

chr10:114900942

ENST00000525508

1939_1945

555.0

1139.0

Compositional bias

Note=Poly-Arg

Hgene

CHD7

chr8:61655656

chr10:114900942

ENST00000525508

2165_2258

555.0

1139.0

Compositional bias

Note=Glu-rich

Hgene

CHD7

chr8:61655656

chr10:114900942

ENST00000525508

2398_2405

555.0

1139.0

Compositional bias

Note=Poly-Arg

Hgene

CHD7

chr8:61655656

chr10:114900942

ENST00000525508

2726_2736

555.0

1139.0

Compositional bias

Note=Poly-Ala

Hgene

CHD7

chr8:61655656

chr10:114900942

ENST00000525508

383_568

555.0

1139.0

Compositional bias

Note=Pro-rich

Hgene

CHD7

chr8:61655656

chr10:114900942

ENST00000525508

597_718

555.0

1139.0

Compositional bias

Note=Lys-rich

Hgene

CHD7

chr8:61655656

chr10:114900943

ENST00000423902

1939_1945

555.0

2998.0

Compositional bias

Note=Poly-Arg

Hgene

CHD7

chr8:61655656

chr10:114900943

ENST00000423902

2165_2258

555.0

2998.0

Compositional bias

Note=Glu-rich

Hgene

CHD7

chr8:61655656

chr10:114900943

ENST00000423902

2398_2405

555.0

2998.0

Compositional bias

Note=Poly-Arg

Hgene

CHD7

chr8:61655656

chr10:114900943

ENST00000423902

2726_2736

555.0

2998.0

Compositional bias

Note=Poly-Ala

Hgene

CHD7

chr8:61655656

chr10:114900943

ENST00000423902

383_568

555.0

2998.0

Compositional bias

Note=Pro-rich

Hgene

CHD7

chr8:61655656

chr10:114900943

ENST00000423902

597_718

555.0

2998.0

Compositional bias

Note=Lys-rich

Hgene

CHD7

chr8:61655656

chr10:114900943

ENST00000524602

1939_1945

555.0

949.0

Compositional bias

Note=Poly-Arg

Hgene

CHD7

chr8:61655656

chr10:114900943

ENST00000524602

2165_2258

555.0

949.0

Compositional bias

Note=Glu-rich

Hgene

CHD7

chr8:61655656

chr10:114900943

ENST00000524602

2398_2405

555.0

949.0

Compositional bias

Note=Poly-Arg

Hgene

CHD7

chr8:61655656

chr10:114900943

ENST00000524602

2726_2736

555.0

949.0

Compositional bias

Note=Poly-Ala

Hgene

CHD7

chr8:61655656

chr10:114900943

ENST00000524602

383_568

555.0

949.0

Compositional bias

Note=Pro-rich

Hgene

CHD7

chr8:61655656

chr10:114900943

ENST00000524602

597_718

555.0

949.0

Compositional bias

Note=Lys-rich

Hgene

CHD7

chr8:61655656

chr10:114900943

ENST00000525508

1939_1945

555.0

1139.0

Compositional bias

Note=Poly-Arg

Hgene

CHD7

chr8:61655656

chr10:114900943

ENST00000525508

2165_2258

555.0

1139.0

Compositional bias

Note=Glu-rich

Hgene

CHD7

chr8:61655656

chr10:114900943

ENST00000525508

2398_2405

555.0

1139.0

Compositional bias

Note=Poly-Arg

Hgene

CHD7

chr8:61655656

chr10:114900943

ENST00000525508

2726_2736

555.0

1139.0

Compositional bias

Note=Poly-Ala

Hgene

CHD7

chr8:61655656

chr10:114900943

ENST00000525508

383_568

555.0

1139.0

Compositional bias

Note=Pro-rich

Hgene

CHD7

chr8:61655656

chr10:114900943

ENST00000525508

597_718

555.0

1139.0

Compositional bias

Note=Lys-rich

Hgene

CHD7

chr8:61655656

chr10:114900942

ENST00000423902

1294_1464

555.0

2998.0

Domain

Helicase C-terminal

Hgene

CHD7

chr8:61655656

chr10:114900942

ENST00000423902

800_867

555.0

2998.0

Domain

Chromo 1

Hgene

CHD7

chr8:61655656

chr10:114900942

ENST00000423902

882_947

555.0

2998.0

Domain

Chromo 2

Hgene

CHD7

chr8:61655656

chr10:114900942

ENST00000423902

980_1154

555.0

2998.0

Domain

Helicase ATP-binding

Hgene

CHD7

chr8:61655656

chr10:114900942

ENST00000524602

1294_1464

555.0

949.0

Domain

Helicase C-terminal

Hgene

CHD7

chr8:61655656

chr10:114900942

ENST00000524602

800_867

555.0

949.0

Domain

Chromo 1

Hgene

CHD7

chr8:61655656

chr10:114900942

ENST00000524602

882_947

555.0

949.0

Domain

Chromo 2

Hgene

CHD7

chr8:61655656

chr10:114900942

ENST00000524602

980_1154

555.0

949.0

Domain

Helicase ATP-binding

Hgene

CHD7

chr8:61655656

chr10:114900942

ENST00000525508

1294_1464

555.0

1139.0

Domain

Helicase C-terminal

Hgene

CHD7

chr8:61655656

chr10:114900942

ENST00000525508

800_867

555.0

1139.0

Domain

Chromo 1

Hgene

CHD7

chr8:61655656

chr10:114900942

ENST00000525508

882_947

555.0

1139.0

Domain

Chromo 2

Hgene

CHD7

chr8:61655656

chr10:114900942

ENST00000525508

980_1154

555.0

1139.0

Domain

Helicase ATP-binding

Hgene

CHD7

chr8:61655656

chr10:114900943

ENST00000423902

1294_1464

555.0

2998.0

Domain

Helicase C-terminal

Hgene

CHD7

chr8:61655656

chr10:114900943

ENST00000423902

800_867

555.0

2998.0

Domain

Chromo 1

Hgene

CHD7

chr8:61655656

chr10:114900943

ENST00000423902

882_947

555.0

2998.0

Domain

Chromo 2

Hgene

CHD7

chr8:61655656

chr10:114900943

ENST00000423902

980_1154

555.0

2998.0

Domain

Helicase ATP-binding

Hgene

CHD7

chr8:61655656

chr10:114900943

ENST00000524602

1294_1464

555.0

949.0

Domain

Helicase C-terminal

Hgene

CHD7

chr8:61655656

chr10:114900943

ENST00000524602

800_867

555.0

949.0

Domain

Chromo 1

Hgene

CHD7

chr8:61655656

chr10:114900943

ENST00000524602

882_947

555.0

949.0

Domain

Chromo 2

Hgene

CHD7

chr8:61655656

chr10:114900943

ENST00000524602

980_1154

555.0

949.0

Domain

Helicase ATP-binding

Hgene

CHD7

chr8:61655656

chr10:114900943

ENST00000525508

1294_1464

555.0

1139.0

Domain

Helicase C-terminal

Hgene

CHD7

chr8:61655656

chr10:114900943

ENST00000525508

800_867

555.0

1139.0

Domain

Chromo 1

Hgene

CHD7

chr8:61655656

chr10:114900943

ENST00000525508

882_947

555.0

1139.0

Domain

Chromo 2

Hgene

CHD7

chr8:61655656

chr10:114900943

ENST00000525508

980_1154

555.0

1139.0

Domain

Helicase ATP-binding

Hgene

CHD7

chr8:61655656

chr10:114900942

ENST00000423902

1105_1108

555.0

2998.0

Motif

Note=DEAH box

Hgene

CHD7

chr8:61655656

chr10:114900942

ENST00000524602

1105_1108

555.0

949.0

Motif

Note=DEAH box

Hgene

CHD7

chr8:61655656

chr10:114900942

ENST00000525508

1105_1108

555.0

1139.0

Motif

Note=DEAH box

Hgene

CHD7

chr8:61655656

chr10:114900943

ENST00000423902

1105_1108

555.0

2998.0

Motif

Note=DEAH box

Hgene

CHD7

chr8:61655656

chr10:114900943

ENST00000524602

1105_1108

555.0

949.0

Motif

Note=DEAH box

Hgene

CHD7

chr8:61655656

chr10:114900943

ENST00000525508

1105_1108

555.0

1139.0

Motif

Note=DEAH box

Hgene

CHD7

chr8:61655656

chr10:114900942

ENST00000423902

993_1000

555.0

2998.0

Nucleotide binding

ATP

Hgene

CHD7

chr8:61655656

chr10:114900942

ENST00000524602

993_1000

555.0

949.0

Nucleotide binding

ATP

Hgene

CHD7

chr8:61655656

chr10:114900942

ENST00000525508

993_1000

555.0

1139.0

Nucleotide binding

ATP

Hgene

CHD7

chr8:61655656

chr10:114900943

ENST00000423902

993_1000

555.0

2998.0

Nucleotide binding

ATP

Hgene

CHD7

chr8:61655656

chr10:114900943

ENST00000524602

993_1000

555.0

949.0

Nucleotide binding

ATP

Hgene

CHD7

chr8:61655656

chr10:114900943

ENST00000525508

993_1000

555.0

1139.0

Nucleotide binding

ATP

Tgene

TCF7L2

chr8:61655656

chr10:114900942

ENST00000355717

178_317

208.0

490.0

Compositional bias

Note=Pro-rich

Tgene

TCF7L2

chr8:61655656

chr10:114900942

ENST00000355995

178_317

184.0

620.0

Compositional bias

Note=Pro-rich

Tgene

TCF7L2

chr8:61655656

chr10:114900942

ENST00000534894

178_317

184.0

495.0

Compositional bias

Note=Pro-rich

Tgene

TCF7L2

chr8:61655656

chr10:114900942

ENST00000536810

178_317

184.0

603.0

Compositional bias

Note=Pro-rich

Tgene

TCF7L2

chr8:61655656

chr10:114900942

ENST00000538897

178_317

184.0

483.0

Compositional bias

Note=Pro-rich

Tgene

TCF7L2

chr8:61655656

chr10:114900942

ENST00000543371

178_317

184.0

603.0

Compositional bias

Note=Pro-rich

Tgene

TCF7L2

chr8:61655656

chr10:114900942

ENST00000545257

178_317

184.0

620.0

Compositional bias

Note=Pro-rich

Tgene

TCF7L2

chr8:61655656

chr10:114900943

ENST00000355717

178_317

208.0

490.0

Compositional bias

Note=Pro-rich

Tgene

TCF7L2

chr8:61655656

chr10:114900943

ENST00000355995

178_317

184.0

620.0

Compositional bias

Note=Pro-rich

Tgene

TCF7L2

chr8:61655656

chr10:114900943

ENST00000534894

178_317

184.0

495.0

Compositional bias

Note=Pro-rich

Tgene

TCF7L2

chr8:61655656

chr10:114900943

ENST00000536810

178_317

184.0

603.0

Compositional bias

Note=Pro-rich

Tgene

TCF7L2

chr8:61655656

chr10:114900943

ENST00000538897

178_317

184.0

483.0

Compositional bias

Note=Pro-rich

Tgene

TCF7L2

chr8:61655656

chr10:114900943

ENST00000543371

178_317

184.0

603.0

Compositional bias

Note=Pro-rich

Tgene

TCF7L2

chr8:61655656

chr10:114900943

ENST00000545257

178_317

184.0

620.0

Compositional bias

Note=Pro-rich

Tgene

TCF7L2

chr8:61655656

chr10:114900942

ENST00000352065

1_53

161.0

386.0

Region

CTNNB1-binding

Tgene

TCF7L2

chr8:61655656

chr10:114900942

ENST00000355717

1_53

208.0

490.0

Region

CTNNB1-binding

Tgene

TCF7L2

chr8:61655656

chr10:114900942

ENST00000355995

1_53

184.0

620.0

Region

CTNNB1-binding

Tgene

TCF7L2

chr8:61655656

chr10:114900942

ENST00000369397

1_53

161.0

597.0

Region

CTNNB1-binding

Tgene

TCF7L2

chr8:61655656

chr10:114900942

ENST00000534894

1_53

184.0

495.0

Region

CTNNB1-binding

Tgene

TCF7L2

chr8:61655656

chr10:114900942

ENST00000536810

1_53

184.0

603.0

Region

CTNNB1-binding

Tgene

TCF7L2

chr8:61655656

chr10:114900942

ENST00000538897

1_53

184.0

483.0

Region

CTNNB1-binding

Tgene

TCF7L2

chr8:61655656

chr10:114900942

ENST00000543371

1_53

184.0

603.0

Region

CTNNB1-binding

Tgene

TCF7L2

chr8:61655656

chr10:114900942

ENST00000545257

1_53

184.0

620.0

Region

CTNNB1-binding

Tgene

TCF7L2

chr8:61655656

chr10:114900943

ENST00000352065

1_53

161.0

386.0

Region

CTNNB1-binding

Tgene

TCF7L2

chr8:61655656

chr10:114900943

ENST00000355717

1_53

208.0

490.0

Region

CTNNB1-binding

Tgene

TCF7L2

chr8:61655656

chr10:114900943

ENST00000355995

1_53

184.0

620.0

Region

CTNNB1-binding

Tgene

TCF7L2

chr8:61655656

chr10:114900943

ENST00000369397

1_53

161.0

597.0

Region

CTNNB1-binding

Tgene

TCF7L2

chr8:61655656

chr10:114900943

ENST00000534894

1_53

184.0

495.0

Region

CTNNB1-binding

Tgene

TCF7L2

chr8:61655656

chr10:114900943

ENST00000536810

1_53

184.0

603.0

Region

CTNNB1-binding

Tgene

TCF7L2

chr8:61655656

chr10:114900943

ENST00000538897

1_53

184.0

483.0

Region

CTNNB1-binding

Tgene

TCF7L2

chr8:61655656

chr10:114900943

ENST00000543371

1_53

184.0

603.0

Region

CTNNB1-binding

Tgene

TCF7L2

chr8:61655656

chr10:114900943

ENST00000545257

1_53

184.0

620.0

Region

CTNNB1-binding

Top

Fusion Protein-Protein Interaction

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type from validated records (BIOGRID-3.4.160)

Gene

PPI interactors

Protein-protein interactors based on sequence similarity (STRING)

Gene	STRING network
CHD7
TCF7L2

- Retained interactions in fusion protein (protein functional feature from UniProt).

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost interactions due to fusion (protein functional feature from UniProt).

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Related Drugs to CHD7-TCF7L2

Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)

Hgene

Tgene

Drug

Source

PMID

Top

Related Diseases to CHD7-TCF7L2

Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)

Hgene

Tgene

Disease

Source

PMID

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner	Gene	Disease ID	Disease name	# pubmeds	Source
Tgene	TCF7L2	C0036341	Schizophrenia	4	PSYGENET
Tgene	TCF7L2	C0011860	Diabetes Mellitus, Non-Insulin-Dependent	3	CTD_human
Tgene	TCF7L2	C0009402	Colorectal Carcinoma	2	CTD_human;UNIPROT
Tgene	TCF7L2	C0009404	Colorectal Neoplasms	2	CTD_human
Tgene	TCF7L2	C0001418	Adenocarcinoma	1	CTD_human
Tgene	TCF7L2	C0005586	Bipolar Disorder	1	PSYGENET
Tgene	TCF7L2	C0007102	Malignant tumor of colon	1	CTD_human
Tgene	TCF7L2	C0007193	Cardiomyopathy, Dilated	1	CTD_human
Tgene	TCF7L2	C0009375	Colonic Neoplasms	1	CTD_human
Tgene	TCF7L2	C0010068	Coronary heart disease	1	CTD_human
Tgene	TCF7L2	C0020507	Hyperplasia	1	CTD_human
Tgene	TCF7L2	C0036337	Schizoaffective Disorder	1	PSYGENET
Tgene	TCF7L2	C0087031	Juvenile-Onset Still Disease	1	CTD_human
Tgene	TCF7L2	C0151744	Myocardial Ischemia	1	CTD_human
Tgene	TCF7L2	C0205641	Adenocarcinoma, Basal Cell	1	CTD_human
Tgene	TCF7L2	C0205642	Adenocarcinoma, Oxyphilic	1	CTD_human
Tgene	TCF7L2	C0205643	Carcinoma, Cribriform	1	CTD_human
Tgene	TCF7L2	C0205644	Carcinoma, Granular Cell	1	CTD_human
Tgene	TCF7L2	C0205645	Adenocarcinoma, Tubular	1	CTD_human
Tgene	TCF7L2	C0600519	Ventricular Remodeling	1	CTD_human
Tgene	TCF7L2	C0600520	Left Ventricle Remodeling	1	CTD_human
Tgene	TCF7L2	C1449563	Cardiomyopathy, Familial Idiopathic	1	CTD_human
Tgene	TCF7L2	C1535926	Neurodevelopmental Disorders	1	CTD_human
Tgene	TCF7L2	C2931456	Prostate cancer, familial	1	CTD_human
Tgene	TCF7L2	C3495559	Juvenile arthritis	1	CTD_human
Tgene	TCF7L2	C3714758	Juvenile psoriatic arthritis	1	CTD_human
Tgene	TCF7L2	C4552091	Polyarthritis, Juvenile, Rheumatoid Factor Negative	1	CTD_human
Tgene	TCF7L2	C4704862	Polyarthritis, Juvenile, Rheumatoid Factor Positive	1	CTD_human
Tgene	TCF7L2	C4722327	PROSTATE CANCER, HEREDITARY, 1	1	CTD_human