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	Fusion Gene Summary
	Fusion Gene Sample Information
	Fusion ORF Analysis
	Fusion Amino Acid Sequences
	Fusion Protein Functional Features
	Fusion Protein Structure
	pLDDT scores
	Ramachandran Plot of Fusion Protein Structure
	Fusion Protein-Protein Interaction
	Related drugs with this fusion protein
	Related disease with this fusion protein

Fusion Protein:CNRIP1-PPP3R1

Fusion Protein Summary

Fusion gene summary

Fusion partner gene information	Fusion gene name: CNRIP1-PPP3R1
	FusionPDB ID: 17846
	FusionGDB2.0 ID: 17846
		Hgene	Tgene
	Gene symbol	CNRIP1	PPP3R1
	Gene ID	25927	5534
	Gene name	cannabinoid receptor interacting protein 1	protein phosphatase 3 regulatory subunit B, alpha
	Synonyms	C2orf32\|CRIP-1\|CRIP1	CALNB1\|CNB\|CNB1
	Cytomap	2p14	2p14
	Type of gene	protein-coding	protein-coding
	Description	CB1 cannabinoid receptor-interacting protein 1cannabinoid receptor CB1-interacting protein 1	calcineurin subunit B type 1calcineurin B, type I (19kDa)protein phosphatase 2B regulatory subunit 1protein phosphatase 2B regulatory subunit B alphaprotein phosphatase 3 (formerly 2B), regulatory subunit B (19kD), alpha isoform (calcineurin B, type I
	Modification date	20200313	20200313
	UniProtAcc	Q96F85	.
Ensembl transtripts involved in fusion gene	ENST ids	ENST00000263655, ENST00000409559, ENST00000481714, ENST00000409862,	ENST00000409377, ENST00000234310, ENST00000409752,
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)	* DoF score	3 X 2 X 3=18	5 X 4 X 4=80
	# samples	4	6
	** MAII score	log2(4/18*10)=1.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0	log2(6/80*10)=-0.415037499278844 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context (manual curation of fusion genes in FusionPDB)	PubMed: CNRIP1 [Title/Abstract] AND PPP3R1 [Title/Abstract] AND fusion [Title/Abstract] A rare genomic duplication in 2p14 underlies autosomal dominant hearing loss DFNA58 (pmid: 32337552)
Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)	PPP3R1(68413600)-CNRIP1(68544439), # samples:2 CNRIP1(68544289)-PPP3R1(68444263), # samples:9
Anticipated loss of major functional domain due to fusion event.	CNRIP1-PPP3R1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. CNRIP1-PPP3R1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. PPP3R1-CNRIP1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. PPP3R1-CNRIP1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. PPP3R1-CNRIP1 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Tgene	PPP3R1	GO:0033173	calcineurin-NFAT signaling cascade	22688515
Tgene	PPP3R1	GO:0045944	positive regulation of transcription by RNA polymerase II	22688515

Fusion gene breakpoints across CNRIP1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across PPP3R1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

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Fusion Gene Sample Information

Fusion gene information from FusionGDB2.0.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	Non-Cancer	61N	CNRIP1	chr2	68544288	-	PPP3R1	chr2	68444263	-
ChimerDB4	Non-Cancer	SPNT_115	CNRIP1	chr2	68544288	-	PPP3R1	chr2	68444263	-
ChimerDB4	Non-Cancer	TCGA-06-0675-11A	CNRIP1	chr2	68544289	-	PPP3R1	chr2	68444263	-
ChimerDB4	Non-Cancer	TCGA-06-0678-11A	CNRIP1	chr2	68544289	-	PPP3R1	chr2	68444263	-
ChimerDB4	Non-Cancer	TCGA-06-0680-11A	CNRIP1	chr2	68544289	-	PPP3R1	chr2	68444263	-
ChimerDB4	Non-Cancer	TCGA-06-0681-11A	CNRIP1	chr2	68544289	-	PPP3R1	chr2	68444263	-
ChimerDB4	Non-Cancer	TCGA-55-6972-11A	CNRIP1	chr2	68544289	-	PPP3R1	chr2	68444263	-
ChimerDB4	Non-Cancer	TCGA-BH-A0DD-11A	CNRIP1	chr2	68544289	-	PPP3R1	chr2	68444263	-
ChimerDB4	Non-Cancer	TCGA-BH-A1EO-11A	CNRIP1	chr2	68544289	-	PPP3R1	chr2	68444263	-
ChimerDB4	Non-Cancer	TCGA-E2-A1LS-11A	CNRIP1	chr2	68544289	-	PPP3R1	chr2	68444263	-
ChimerDB4	Non-Cancer	TCGA-E9-A1RC-11A	CNRIP1	chr2	68544289	-	PPP3R1	chr2	68444263	-

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Fusion ORF Analysis

Fusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000409559	CNRIP1	chr2	68544288	-	ENST00000234310	PPP3R1	chr2	68444263	-	2946	330	0	839	279
ENST00000409559	CNRIP1	chr2	68544288	-	ENST00000409752	PPP3R1	chr2	68444263	-	999	330	0	839	279
ENST00000263655	CNRIP1	chr2	68544288	-	ENST00000234310	PPP3R1	chr2	68444263	-	3552	936	606	1445	279
ENST00000263655	CNRIP1	chr2	68544288	-	ENST00000409752	PPP3R1	chr2	68444263	-	1605	936	606	1445	279
ENST00000409559	CNRIP1	chr2	68544289	-	ENST00000234310	PPP3R1	chr2	68444263	-	2946	330	0	839	279
ENST00000409559	CNRIP1	chr2	68544289	-	ENST00000409752	PPP3R1	chr2	68444263	-	999	330	0	839	279
ENST00000263655	CNRIP1	chr2	68544289	-	ENST00000234310	PPP3R1	chr2	68444263	-	3552	936	606	1445	279
ENST00000263655	CNRIP1	chr2	68544289	-	ENST00000409752	PPP3R1	chr2	68444263	-	1605	936	606	1445	279

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000409559	ENST00000234310	CNRIP1	chr2	68544288	-	PPP3R1	chr2	68444263	-	4.58E-05	0.9999542
ENST00000409559	ENST00000409752	CNRIP1	chr2	68544288	-	PPP3R1	chr2	68444263	-	0.000137032	0.9998629
ENST00000263655	ENST00000234310	CNRIP1	chr2	68544288	-	PPP3R1	chr2	68444263	-	5.84E-05	0.9999416
ENST00000263655	ENST00000409752	CNRIP1	chr2	68544288	-	PPP3R1	chr2	68444263	-	0.000372172	0.9996278
ENST00000409559	ENST00000234310	CNRIP1	chr2	68544289	-	PPP3R1	chr2	68444263	-	4.58E-05	0.9999542
ENST00000409559	ENST00000409752	CNRIP1	chr2	68544289	-	PPP3R1	chr2	68444263	-	0.000137032	0.9998629
ENST00000263655	ENST00000234310	CNRIP1	chr2	68544289	-	PPP3R1	chr2	68444263	-	5.84E-05	0.9999416
ENST00000263655	ENST00000409752	CNRIP1	chr2	68544289	-	PPP3R1	chr2	68444263	-	0.000372172	0.9996278

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Fusion Amino Acid Sequences

For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

>17846_17846_1_CNRIP1-PPP3R1_CNRIP1_chr2_68544288_ENST00000263655_PPP3R1_chr2_68444263_ENST00000234310_length(amino acids)=279AA_BP=0
MGDLPGLVRLSIALRIQPNDGPVFYKVDGQRFGQNRTIKLLTGSSYKVEVKIKPSTLQVENISIGGVLVPLELKSKEPDGDRVVYTGTYD
TEGVTPTKSGERQPIQITMPGNEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVD
FKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLD

--------------------------------------------------------------

>17846_17846_2_CNRIP1-PPP3R1_CNRIP1_chr2_68544288_ENST00000263655_PPP3R1_chr2_68444263_ENST00000409752_length(amino acids)=279AA_BP=0
MGDLPGLVRLSIALRIQPNDGPVFYKVDGQRFGQNRTIKLLTGSSYKVEVKIKPSTLQVENISIGGVLVPLELKSKEPDGDRVVYTGTYD
TEGVTPTKSGERQPIQITMPGNEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVD
FKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLD

--------------------------------------------------------------

>17846_17846_3_CNRIP1-PPP3R1_CNRIP1_chr2_68544288_ENST00000409559_PPP3R1_chr2_68444263_ENST00000234310_length(amino acids)=279AA_BP=0
MGDLPGLVRLSIALRIQPNDGPVFYKVDGQRFGQNRTIKLLTGSSYKVEVKIKPSTLQVENISIGGVLVPLELKSKEPDGDRVVYTGTYD
TEGVTPTKSGERQPIQITMPGNEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVD
FKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLD

--------------------------------------------------------------

>17846_17846_4_CNRIP1-PPP3R1_CNRIP1_chr2_68544288_ENST00000409559_PPP3R1_chr2_68444263_ENST00000409752_length(amino acids)=279AA_BP=0
MGDLPGLVRLSIALRIQPNDGPVFYKVDGQRFGQNRTIKLLTGSSYKVEVKIKPSTLQVENISIGGVLVPLELKSKEPDGDRVVYTGTYD
TEGVTPTKSGERQPIQITMPGNEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVD
FKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLD

--------------------------------------------------------------

>17846_17846_5_CNRIP1-PPP3R1_CNRIP1_chr2_68544289_ENST00000263655_PPP3R1_chr2_68444263_ENST00000234310_length(amino acids)=279AA_BP=0
MGDLPGLVRLSIALRIQPNDGPVFYKVDGQRFGQNRTIKLLTGSSYKVEVKIKPSTLQVENISIGGVLVPLELKSKEPDGDRVVYTGTYD
TEGVTPTKSGERQPIQITMPGNEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVD
FKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLD

--------------------------------------------------------------

>17846_17846_6_CNRIP1-PPP3R1_CNRIP1_chr2_68544289_ENST00000263655_PPP3R1_chr2_68444263_ENST00000409752_length(amino acids)=279AA_BP=0
MGDLPGLVRLSIALRIQPNDGPVFYKVDGQRFGQNRTIKLLTGSSYKVEVKIKPSTLQVENISIGGVLVPLELKSKEPDGDRVVYTGTYD
TEGVTPTKSGERQPIQITMPGNEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVD
FKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLD

--------------------------------------------------------------

>17846_17846_7_CNRIP1-PPP3R1_CNRIP1_chr2_68544289_ENST00000409559_PPP3R1_chr2_68444263_ENST00000234310_length(amino acids)=279AA_BP=0
MGDLPGLVRLSIALRIQPNDGPVFYKVDGQRFGQNRTIKLLTGSSYKVEVKIKPSTLQVENISIGGVLVPLELKSKEPDGDRVVYTGTYD
TEGVTPTKSGERQPIQITMPGNEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVD
FKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLD

--------------------------------------------------------------

>17846_17846_8_CNRIP1-PPP3R1_CNRIP1_chr2_68544289_ENST00000409559_PPP3R1_chr2_68444263_ENST00000409752_length(amino acids)=279AA_BP=0
MGDLPGLVRLSIALRIQPNDGPVFYKVDGQRFGQNRTIKLLTGSSYKVEVKIKPSTLQVENISIGGVLVPLELKSKEPDGDRVVYTGTYD
TEGVTPTKSGERQPIQITMPGNEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVD
FKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLD

--------------------------------------------------------------

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Fusion Protein Functional Features

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr2:68413600/chr2:68544439)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
CNRIP1 Q96F85	.
FUNCTION: [Isoform 1]: Suppresses cannabinoid receptor CNR1-mediated tonic inhibition of voltage-gated calcium channels. {ECO:0000269\|PubMed:17895407}.; FUNCTION: [Isoform 2]: Does not suppress cannabinoid receptor CNR1-mediated tonic inhibition of voltage-gated calcium channels. {ECO:0000269\|PubMed:17895407}.	FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page
* Minus value of BPloci means that the break pointn is located before the CDS.

- Retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Tgene

PPP3R1

chr2:68544288

chr2:68444263

ENST00000234310

100_111

1.0

171.0

Calcium binding

Tgene

PPP3R1

chr2:68544288

chr2:68444263

ENST00000234310

141_152

1.0

171.0

Calcium binding

Tgene

PPP3R1

chr2:68544288

chr2:68444263

ENST00000234310

31_42

1.0

171.0

Calcium binding

Tgene

PPP3R1

chr2:68544288

chr2:68444263

ENST00000234310

63_74

1.0

171.0

Calcium binding

Tgene

PPP3R1

chr2:68544289

chr2:68444263

ENST00000234310

100_111

1.0

171.0

Calcium binding

Tgene

PPP3R1

chr2:68544289

chr2:68444263

ENST00000234310

141_152

1.0

171.0

Calcium binding

Tgene

PPP3R1

chr2:68544289

chr2:68444263

ENST00000234310

31_42

1.0

171.0

Calcium binding

Tgene

PPP3R1

chr2:68544289

chr2:68444263

ENST00000234310

63_74

1.0

171.0

Calcium binding

Tgene

PPP3R1

chr2:68544288

chr2:68444263

ENST00000234310

128_163

1.0

171.0

Domain

EF-hand 4

Tgene

PPP3R1

chr2:68544288

chr2:68444263

ENST00000234310

18_51

1.0

171.0

Domain

EF-hand 1

Tgene

PPP3R1

chr2:68544288

chr2:68444263

ENST00000234310

50_85

1.0

171.0

Domain

EF-hand 2

Tgene

PPP3R1

chr2:68544288

chr2:68444263

ENST00000234310

87_122

1.0

171.0

Domain

EF-hand 3

Tgene

PPP3R1

chr2:68544289

chr2:68444263

ENST00000234310

128_163

1.0

171.0

Domain

EF-hand 4

Tgene

PPP3R1

chr2:68544289

chr2:68444263

ENST00000234310

18_51

1.0

171.0

Domain

EF-hand 1

Tgene

PPP3R1

chr2:68544289

chr2:68444263

ENST00000234310

50_85

1.0

171.0

Domain

EF-hand 2

Tgene

PPP3R1

chr2:68544289

chr2:68444263

ENST00000234310

87_122

1.0

171.0

Domain

EF-hand 3

Tgene

PPP3R1

chr2:68544288

chr2:68444263

ENST00000234310

131_136

1.0

171.0

Region

Calcineurin A binding

Tgene

PPP3R1

chr2:68544289

chr2:68444263

ENST00000234310

131_136

1.0

171.0

Region

Calcineurin A binding

- Not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

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Fusion Protein Structures

PDB and CIF files of the predicted fusion proteins
* Here we show the 3D structure of the fusion proteins using Mol*. AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Model confidence is shown from the pLDDT values per residue. pLDDT corresponds to the model’s prediction of its score on the local Distance Difference Test. It is a measure of local accuracy (from AlphfaFold website). To color code individual residues, we transformed individual PDB files into CIF format.

Fusion protein PDB link (fusion AA seq ID in FusionPDB)	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	AA seq	Len(AA seq)
PDB file >>>482_CNRIP1_68544289_PPP3R1_68444263_ranked_0.pdb	CNRIP1	68544289	68544289	ENST00000409752	PPP3R1	chr2	68444263	-	MGDLPGLVRLSIALRIQPNDGPVFYKVDGQRFGQNRTIKLLTGSSYKVEVKIKPSTLQVENISIGGVLVPLELKSKEPDGDRVVYTGTYD TEGVTPTKSGERQPIQITMPGNEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVD FKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLD	279

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pLDDT score distribution

pLDDT score distribution of the predicted wild-type structures of two partner proteins from AlphaFold2
* AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100.

CNRIP1_pLDDT.png

PPP3R1_pLDDT.png

pLDDT score distribution of the predicted fusion protein structures from AlphaFold2
* AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100.

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Ramachandran Plot of Fusion Protein Structure

Ramachandran plot of the torsional angles - phi (φ)and psi (ψ) - of the residues (amino acids) contained in this fusion protein peptide.

Fusion AA seq ID in FusionPDB and their Ramachandran plots

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Fusion Protein-Protein Interaction

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type from validated records (BIOGRID-3.4.160)

Gene

PPI interactors

Protein-protein interactors based on sequence similarity (STRING)

Gene	STRING network
CNRIP1
PPP3R1

- Retained interactions in fusion protein (protein functional feature from UniProt).

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost interactions due to fusion (protein functional feature from UniProt).

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

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Related Drugs to CNRIP1-PPP3R1

Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)

Hgene

Tgene

Drug

Source

PMID

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Related Diseases to CNRIP1-PPP3R1

Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)

Hgene

Tgene

Disease

Source

PMID

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source