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Center for Computational Systems Medicine level1
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Fusion Gene Summary

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Fusion Gene Sample Information

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Fusion ORF Analysis

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Fusion Amino Acid Sequences

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Fusion Protein Functional Features

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Fusion Protein-Protein Interaction

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Related drugs with this fusion protein

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Related disease with this fusion protein

Fusion Protein:CPT1A-ADAM2

Fusion Protein Summary

check button Fusion gene summary
Fusion partner gene informationFusion gene name: CPT1A-ADAM2
FusionPDB ID: 19209
FusionGDB2.0 ID: 19209
HgeneTgene
Gene symbol

CPT1A

ADAM2

Gene ID

1374

2515

Gene namecarnitine palmitoyltransferase 1AADAM metallopeptidase domain 2
SynonymsCPT1|CPT1-L|L-CPT1CRYN1|CRYN2|CT15|FTNB|PH-30b|PH30|PH30-beta
Cytomap

11q13.3

8p11.22

Type of geneprotein-codingprotein-coding
Descriptioncarnitine O-palmitoyltransferase 1, liver isoformCPT ICPTI-Lcarnitine O-palmitoyltransferase I, liver isoformcarnitine palmitoyltransferase 1A (liver)carnitine palmitoyltransferase I, liverdisintegrin and metalloproteinase domain-containing protein 2cancer/testis antigen 15fertilin subunit beta
Modification date2020031520200313
UniProtAcc

P50416

Q9UKF5

Ensembl transtripts involved in fusion geneENST idsENST00000265641, ENST00000376618, 
ENST00000539743, ENST00000540367, 
ENST00000537756, ENST00000538994, 
ENST00000523181, ENST00000265708, 
ENST00000347580, ENST00000379853, 
ENST00000521880, 
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)* DoF score25 X 23 X 12=69007 X 8 X 4=224
# samples 3210
** MAII scorelog2(32/6900*10)=-4.43045255166553
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(10/224*10)=-1.16349873228288
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context (manual curation of fusion genes in FusionPDB)

PubMed: CPT1A [Title/Abstract] AND ADAM2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)CPT1A(68540733)-ADAM2(39607263), # samples:3
Anticipated loss of major functional domain due to fusion event.CPT1A-ADAM2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
CPT1A-ADAM2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
CPT1A-ADAM2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
CPT1A-ADAM2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
CPT1A-ADAM2 seems lost the major protein functional domain in Hgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
CPT1A-ADAM2 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
CPT1A-ADAM2 seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneCPT1A

GO:0001676

long-chain fatty acid metabolic process

11350182

HgeneCPT1A

GO:0009437

carnitine metabolic process

11350182


check buttonFusion gene breakpoints across CPT1A (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across ADAM2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure


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Fusion Gene Sample Information

check buttonFusion gene information from FusionGDB2.0.
check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-E2-A15R-01ACPT1Achr11

68540733

-ADAM2chr8

39607263

-
ChimerDB4BRCATCGA-E2-A15RCPT1Achr11

68540732

-ADAM2chr8

39607263

-


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Fusion ORF Analysis


check buttonFusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000540367CPT1Achr1168540733-ENST00000347580ADAM2chr839607263-25401769232179718
ENST00000540367CPT1Achr1168540733-ENST00000379853ADAM2chr839607263-25401769232179718
ENST00000540367CPT1Achr1168540733-ENST00000265708ADAM2chr839607263-25401769232179718
ENST00000540367CPT1Achr1168540733-ENST00000521880ADAM2chr839607263-22441769232179718
ENST00000539743CPT1Achr1168540733-ENST00000347580ADAM2chr839607263-25401769232179718
ENST00000539743CPT1Achr1168540733-ENST00000379853ADAM2chr839607263-25401769232179718
ENST00000539743CPT1Achr1168540733-ENST00000265708ADAM2chr839607263-25401769232179718
ENST00000539743CPT1Achr1168540733-ENST00000521880ADAM2chr839607263-22441769232179718
ENST00000540367CPT1Achr1168540732-ENST00000347580ADAM2chr839607263-25401769232179718
ENST00000540367CPT1Achr1168540732-ENST00000379853ADAM2chr839607263-25401769232179718
ENST00000540367CPT1Achr1168540732-ENST00000265708ADAM2chr839607263-25401769232179718
ENST00000540367CPT1Achr1168540732-ENST00000521880ADAM2chr839607263-22441769232179718
ENST00000539743CPT1Achr1168540732-ENST00000347580ADAM2chr839607263-25401769232179718
ENST00000539743CPT1Achr1168540732-ENST00000379853ADAM2chr839607263-25401769232179718
ENST00000539743CPT1Achr1168540732-ENST00000265708ADAM2chr839607263-25401769232179718
ENST00000539743CPT1Achr1168540732-ENST00000521880ADAM2chr839607263-22441769232179718

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000540367ENST00000347580CPT1Achr1168540733-ADAM2chr839607263-0.0007873070.9992126
ENST00000540367ENST00000379853CPT1Achr1168540733-ADAM2chr839607263-0.0007873070.9992126
ENST00000540367ENST00000265708CPT1Achr1168540733-ADAM2chr839607263-0.0007873070.9992126
ENST00000540367ENST00000521880CPT1Achr1168540733-ADAM2chr839607263-0.0020770680.99792296
ENST00000539743ENST00000347580CPT1Achr1168540733-ADAM2chr839607263-0.0007873070.9992126
ENST00000539743ENST00000379853CPT1Achr1168540733-ADAM2chr839607263-0.0007873070.9992126
ENST00000539743ENST00000265708CPT1Achr1168540733-ADAM2chr839607263-0.0007873070.9992126
ENST00000539743ENST00000521880CPT1Achr1168540733-ADAM2chr839607263-0.0020770680.99792296
ENST00000540367ENST00000347580CPT1Achr1168540732-ADAM2chr839607263-0.0007873070.9992126
ENST00000540367ENST00000379853CPT1Achr1168540732-ADAM2chr839607263-0.0007873070.9992126
ENST00000540367ENST00000265708CPT1Achr1168540732-ADAM2chr839607263-0.0007873070.9992126
ENST00000540367ENST00000521880CPT1Achr1168540732-ADAM2chr839607263-0.0020770680.99792296
ENST00000539743ENST00000347580CPT1Achr1168540732-ADAM2chr839607263-0.0007873070.9992126
ENST00000539743ENST00000379853CPT1Achr1168540732-ADAM2chr839607263-0.0007873070.9992126
ENST00000539743ENST00000265708CPT1Achr1168540732-ADAM2chr839607263-0.0007873070.9992126
ENST00000539743ENST00000521880CPT1Achr1168540732-ADAM2chr839607263-0.0020770680.99792296

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Fusion Amino Acid Sequences


check button For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

>19209_19209_1_CPT1A-ADAM2_CPT1A_chr11_68540732_ENST00000539743_ADAM2_chr8_39607263_ENST00000265708_length(amino acids)=718AA_BP=582
MKMAEAHQAVAFQFTVTPDGIDLRLSHEALRQIYLSGLHSWKKKFIRFKNGIITGVYPASPSSWLIVVVGVMTTMYAKIDPSLGIIAKIN
RTLETANCMSSQTKNVVSGVLFGTGLWVALIVTMRYSLKVLLSYHGWMFTEHGKMSRATKIWMGMVKIFSGRKPMLYSFQTSLPRLPVPA
VKDTVNRYLQSVRPLMKEEDFKRMTALAQDFAVGLGPRLQWYLKLKSWWATNYVSDWWEEYIYLRGRGPLMVNSNYYAMDLLYILPTHIQ
AARAGNAIHAILLYRRKLDREEIKPIRLLGSTIPLCSAQWERMFNTSRIPGEETDTIQHMRDSKHIVVYHRGRYFKVWLYHDGRLLKPRE
MEQQMQRILDNTSEPQPGEARLAALTAGDRVPWARCRQAYFGRGKNKQSLDAVEKAAFFVTLDETEEGYRSEDPDTSMDSYAKSLLHGRC
YDRWFDKSFTFVVFKNGKMGLNAEHSWADAPIVAHLWEYVMSIDSLQLGYAEDGHCKGDINPNIPYPTRLQWDIPGECQEVIETSLNTAN
LLANDVDFHSFPFVAFGKGIIKKCRTSPDAFVQLALQLAHYKVCRNQRCVSSSYLGYDCTTDKCNDRGVCNNKKHCHCSASYLPPDCSVQ

--------------------------------------------------------------

>19209_19209_2_CPT1A-ADAM2_CPT1A_chr11_68540732_ENST00000539743_ADAM2_chr8_39607263_ENST00000347580_length(amino acids)=718AA_BP=582
MKMAEAHQAVAFQFTVTPDGIDLRLSHEALRQIYLSGLHSWKKKFIRFKNGIITGVYPASPSSWLIVVVGVMTTMYAKIDPSLGIIAKIN
RTLETANCMSSQTKNVVSGVLFGTGLWVALIVTMRYSLKVLLSYHGWMFTEHGKMSRATKIWMGMVKIFSGRKPMLYSFQTSLPRLPVPA
VKDTVNRYLQSVRPLMKEEDFKRMTALAQDFAVGLGPRLQWYLKLKSWWATNYVSDWWEEYIYLRGRGPLMVNSNYYAMDLLYILPTHIQ
AARAGNAIHAILLYRRKLDREEIKPIRLLGSTIPLCSAQWERMFNTSRIPGEETDTIQHMRDSKHIVVYHRGRYFKVWLYHDGRLLKPRE
MEQQMQRILDNTSEPQPGEARLAALTAGDRVPWARCRQAYFGRGKNKQSLDAVEKAAFFVTLDETEEGYRSEDPDTSMDSYAKSLLHGRC
YDRWFDKSFTFVVFKNGKMGLNAEHSWADAPIVAHLWEYVMSIDSLQLGYAEDGHCKGDINPNIPYPTRLQWDIPGECQEVIETSLNTAN
LLANDVDFHSFPFVAFGKGIIKKCRTSPDAFVQLALQLAHYKVCRNQRCVSSSYLGYDCTTDKCNDRGVCNNKKHCHCSASYLPPDCSVQ

--------------------------------------------------------------

>19209_19209_3_CPT1A-ADAM2_CPT1A_chr11_68540732_ENST00000539743_ADAM2_chr8_39607263_ENST00000379853_length(amino acids)=718AA_BP=582
MKMAEAHQAVAFQFTVTPDGIDLRLSHEALRQIYLSGLHSWKKKFIRFKNGIITGVYPASPSSWLIVVVGVMTTMYAKIDPSLGIIAKIN
RTLETANCMSSQTKNVVSGVLFGTGLWVALIVTMRYSLKVLLSYHGWMFTEHGKMSRATKIWMGMVKIFSGRKPMLYSFQTSLPRLPVPA
VKDTVNRYLQSVRPLMKEEDFKRMTALAQDFAVGLGPRLQWYLKLKSWWATNYVSDWWEEYIYLRGRGPLMVNSNYYAMDLLYILPTHIQ
AARAGNAIHAILLYRRKLDREEIKPIRLLGSTIPLCSAQWERMFNTSRIPGEETDTIQHMRDSKHIVVYHRGRYFKVWLYHDGRLLKPRE
MEQQMQRILDNTSEPQPGEARLAALTAGDRVPWARCRQAYFGRGKNKQSLDAVEKAAFFVTLDETEEGYRSEDPDTSMDSYAKSLLHGRC
YDRWFDKSFTFVVFKNGKMGLNAEHSWADAPIVAHLWEYVMSIDSLQLGYAEDGHCKGDINPNIPYPTRLQWDIPGECQEVIETSLNTAN
LLANDVDFHSFPFVAFGKGIIKKCRTSPDAFVQLALQLAHYKVCRNQRCVSSSYLGYDCTTDKCNDRGVCNNKKHCHCSASYLPPDCSVQ

--------------------------------------------------------------

>19209_19209_4_CPT1A-ADAM2_CPT1A_chr11_68540732_ENST00000539743_ADAM2_chr8_39607263_ENST00000521880_length(amino acids)=718AA_BP=582
MKMAEAHQAVAFQFTVTPDGIDLRLSHEALRQIYLSGLHSWKKKFIRFKNGIITGVYPASPSSWLIVVVGVMTTMYAKIDPSLGIIAKIN
RTLETANCMSSQTKNVVSGVLFGTGLWVALIVTMRYSLKVLLSYHGWMFTEHGKMSRATKIWMGMVKIFSGRKPMLYSFQTSLPRLPVPA
VKDTVNRYLQSVRPLMKEEDFKRMTALAQDFAVGLGPRLQWYLKLKSWWATNYVSDWWEEYIYLRGRGPLMVNSNYYAMDLLYILPTHIQ
AARAGNAIHAILLYRRKLDREEIKPIRLLGSTIPLCSAQWERMFNTSRIPGEETDTIQHMRDSKHIVVYHRGRYFKVWLYHDGRLLKPRE
MEQQMQRILDNTSEPQPGEARLAALTAGDRVPWARCRQAYFGRGKNKQSLDAVEKAAFFVTLDETEEGYRSEDPDTSMDSYAKSLLHGRC
YDRWFDKSFTFVVFKNGKMGLNAEHSWADAPIVAHLWEYVMSIDSLQLGYAEDGHCKGDINPNIPYPTRLQWDIPGECQEVIETSLNTAN
LLANDVDFHSFPFVAFGKGIIKKCRTSPDAFVQLALQLAHYKVCRNQRCVSSSYLGYDCTTDKCNDRGVCNNKKHCHCSASYLPPDCSVQ

--------------------------------------------------------------

>19209_19209_5_CPT1A-ADAM2_CPT1A_chr11_68540732_ENST00000540367_ADAM2_chr8_39607263_ENST00000265708_length(amino acids)=718AA_BP=582
MKMAEAHQAVAFQFTVTPDGIDLRLSHEALRQIYLSGLHSWKKKFIRFKNGIITGVYPASPSSWLIVVVGVMTTMYAKIDPSLGIIAKIN
RTLETANCMSSQTKNVVSGVLFGTGLWVALIVTMRYSLKVLLSYHGWMFTEHGKMSRATKIWMGMVKIFSGRKPMLYSFQTSLPRLPVPA
VKDTVNRYLQSVRPLMKEEDFKRMTALAQDFAVGLGPRLQWYLKLKSWWATNYVSDWWEEYIYLRGRGPLMVNSNYYAMDLLYILPTHIQ
AARAGNAIHAILLYRRKLDREEIKPIRLLGSTIPLCSAQWERMFNTSRIPGEETDTIQHMRDSKHIVVYHRGRYFKVWLYHDGRLLKPRE
MEQQMQRILDNTSEPQPGEARLAALTAGDRVPWARCRQAYFGRGKNKQSLDAVEKAAFFVTLDETEEGYRSEDPDTSMDSYAKSLLHGRC
YDRWFDKSFTFVVFKNGKMGLNAEHSWADAPIVAHLWEYVMSIDSLQLGYAEDGHCKGDINPNIPYPTRLQWDIPGECQEVIETSLNTAN
LLANDVDFHSFPFVAFGKGIIKKCRTSPDAFVQLALQLAHYKVCRNQRCVSSSYLGYDCTTDKCNDRGVCNNKKHCHCSASYLPPDCSVQ

--------------------------------------------------------------

>19209_19209_6_CPT1A-ADAM2_CPT1A_chr11_68540732_ENST00000540367_ADAM2_chr8_39607263_ENST00000347580_length(amino acids)=718AA_BP=582
MKMAEAHQAVAFQFTVTPDGIDLRLSHEALRQIYLSGLHSWKKKFIRFKNGIITGVYPASPSSWLIVVVGVMTTMYAKIDPSLGIIAKIN
RTLETANCMSSQTKNVVSGVLFGTGLWVALIVTMRYSLKVLLSYHGWMFTEHGKMSRATKIWMGMVKIFSGRKPMLYSFQTSLPRLPVPA
VKDTVNRYLQSVRPLMKEEDFKRMTALAQDFAVGLGPRLQWYLKLKSWWATNYVSDWWEEYIYLRGRGPLMVNSNYYAMDLLYILPTHIQ
AARAGNAIHAILLYRRKLDREEIKPIRLLGSTIPLCSAQWERMFNTSRIPGEETDTIQHMRDSKHIVVYHRGRYFKVWLYHDGRLLKPRE
MEQQMQRILDNTSEPQPGEARLAALTAGDRVPWARCRQAYFGRGKNKQSLDAVEKAAFFVTLDETEEGYRSEDPDTSMDSYAKSLLHGRC
YDRWFDKSFTFVVFKNGKMGLNAEHSWADAPIVAHLWEYVMSIDSLQLGYAEDGHCKGDINPNIPYPTRLQWDIPGECQEVIETSLNTAN
LLANDVDFHSFPFVAFGKGIIKKCRTSPDAFVQLALQLAHYKVCRNQRCVSSSYLGYDCTTDKCNDRGVCNNKKHCHCSASYLPPDCSVQ

--------------------------------------------------------------

>19209_19209_7_CPT1A-ADAM2_CPT1A_chr11_68540732_ENST00000540367_ADAM2_chr8_39607263_ENST00000379853_length(amino acids)=718AA_BP=582
MKMAEAHQAVAFQFTVTPDGIDLRLSHEALRQIYLSGLHSWKKKFIRFKNGIITGVYPASPSSWLIVVVGVMTTMYAKIDPSLGIIAKIN
RTLETANCMSSQTKNVVSGVLFGTGLWVALIVTMRYSLKVLLSYHGWMFTEHGKMSRATKIWMGMVKIFSGRKPMLYSFQTSLPRLPVPA
VKDTVNRYLQSVRPLMKEEDFKRMTALAQDFAVGLGPRLQWYLKLKSWWATNYVSDWWEEYIYLRGRGPLMVNSNYYAMDLLYILPTHIQ
AARAGNAIHAILLYRRKLDREEIKPIRLLGSTIPLCSAQWERMFNTSRIPGEETDTIQHMRDSKHIVVYHRGRYFKVWLYHDGRLLKPRE
MEQQMQRILDNTSEPQPGEARLAALTAGDRVPWARCRQAYFGRGKNKQSLDAVEKAAFFVTLDETEEGYRSEDPDTSMDSYAKSLLHGRC
YDRWFDKSFTFVVFKNGKMGLNAEHSWADAPIVAHLWEYVMSIDSLQLGYAEDGHCKGDINPNIPYPTRLQWDIPGECQEVIETSLNTAN
LLANDVDFHSFPFVAFGKGIIKKCRTSPDAFVQLALQLAHYKVCRNQRCVSSSYLGYDCTTDKCNDRGVCNNKKHCHCSASYLPPDCSVQ

--------------------------------------------------------------

>19209_19209_8_CPT1A-ADAM2_CPT1A_chr11_68540732_ENST00000540367_ADAM2_chr8_39607263_ENST00000521880_length(amino acids)=718AA_BP=582
MKMAEAHQAVAFQFTVTPDGIDLRLSHEALRQIYLSGLHSWKKKFIRFKNGIITGVYPASPSSWLIVVVGVMTTMYAKIDPSLGIIAKIN
RTLETANCMSSQTKNVVSGVLFGTGLWVALIVTMRYSLKVLLSYHGWMFTEHGKMSRATKIWMGMVKIFSGRKPMLYSFQTSLPRLPVPA
VKDTVNRYLQSVRPLMKEEDFKRMTALAQDFAVGLGPRLQWYLKLKSWWATNYVSDWWEEYIYLRGRGPLMVNSNYYAMDLLYILPTHIQ
AARAGNAIHAILLYRRKLDREEIKPIRLLGSTIPLCSAQWERMFNTSRIPGEETDTIQHMRDSKHIVVYHRGRYFKVWLYHDGRLLKPRE
MEQQMQRILDNTSEPQPGEARLAALTAGDRVPWARCRQAYFGRGKNKQSLDAVEKAAFFVTLDETEEGYRSEDPDTSMDSYAKSLLHGRC
YDRWFDKSFTFVVFKNGKMGLNAEHSWADAPIVAHLWEYVMSIDSLQLGYAEDGHCKGDINPNIPYPTRLQWDIPGECQEVIETSLNTAN
LLANDVDFHSFPFVAFGKGIIKKCRTSPDAFVQLALQLAHYKVCRNQRCVSSSYLGYDCTTDKCNDRGVCNNKKHCHCSASYLPPDCSVQ

--------------------------------------------------------------

>19209_19209_9_CPT1A-ADAM2_CPT1A_chr11_68540733_ENST00000539743_ADAM2_chr8_39607263_ENST00000265708_length(amino acids)=718AA_BP=582
MKMAEAHQAVAFQFTVTPDGIDLRLSHEALRQIYLSGLHSWKKKFIRFKNGIITGVYPASPSSWLIVVVGVMTTMYAKIDPSLGIIAKIN
RTLETANCMSSQTKNVVSGVLFGTGLWVALIVTMRYSLKVLLSYHGWMFTEHGKMSRATKIWMGMVKIFSGRKPMLYSFQTSLPRLPVPA
VKDTVNRYLQSVRPLMKEEDFKRMTALAQDFAVGLGPRLQWYLKLKSWWATNYVSDWWEEYIYLRGRGPLMVNSNYYAMDLLYILPTHIQ
AARAGNAIHAILLYRRKLDREEIKPIRLLGSTIPLCSAQWERMFNTSRIPGEETDTIQHMRDSKHIVVYHRGRYFKVWLYHDGRLLKPRE
MEQQMQRILDNTSEPQPGEARLAALTAGDRVPWARCRQAYFGRGKNKQSLDAVEKAAFFVTLDETEEGYRSEDPDTSMDSYAKSLLHGRC
YDRWFDKSFTFVVFKNGKMGLNAEHSWADAPIVAHLWEYVMSIDSLQLGYAEDGHCKGDINPNIPYPTRLQWDIPGECQEVIETSLNTAN
LLANDVDFHSFPFVAFGKGIIKKCRTSPDAFVQLALQLAHYKVCRNQRCVSSSYLGYDCTTDKCNDRGVCNNKKHCHCSASYLPPDCSVQ

--------------------------------------------------------------

>19209_19209_10_CPT1A-ADAM2_CPT1A_chr11_68540733_ENST00000539743_ADAM2_chr8_39607263_ENST00000347580_length(amino acids)=718AA_BP=582
MKMAEAHQAVAFQFTVTPDGIDLRLSHEALRQIYLSGLHSWKKKFIRFKNGIITGVYPASPSSWLIVVVGVMTTMYAKIDPSLGIIAKIN
RTLETANCMSSQTKNVVSGVLFGTGLWVALIVTMRYSLKVLLSYHGWMFTEHGKMSRATKIWMGMVKIFSGRKPMLYSFQTSLPRLPVPA
VKDTVNRYLQSVRPLMKEEDFKRMTALAQDFAVGLGPRLQWYLKLKSWWATNYVSDWWEEYIYLRGRGPLMVNSNYYAMDLLYILPTHIQ
AARAGNAIHAILLYRRKLDREEIKPIRLLGSTIPLCSAQWERMFNTSRIPGEETDTIQHMRDSKHIVVYHRGRYFKVWLYHDGRLLKPRE
MEQQMQRILDNTSEPQPGEARLAALTAGDRVPWARCRQAYFGRGKNKQSLDAVEKAAFFVTLDETEEGYRSEDPDTSMDSYAKSLLHGRC
YDRWFDKSFTFVVFKNGKMGLNAEHSWADAPIVAHLWEYVMSIDSLQLGYAEDGHCKGDINPNIPYPTRLQWDIPGECQEVIETSLNTAN
LLANDVDFHSFPFVAFGKGIIKKCRTSPDAFVQLALQLAHYKVCRNQRCVSSSYLGYDCTTDKCNDRGVCNNKKHCHCSASYLPPDCSVQ

--------------------------------------------------------------

>19209_19209_11_CPT1A-ADAM2_CPT1A_chr11_68540733_ENST00000539743_ADAM2_chr8_39607263_ENST00000379853_length(amino acids)=718AA_BP=582
MKMAEAHQAVAFQFTVTPDGIDLRLSHEALRQIYLSGLHSWKKKFIRFKNGIITGVYPASPSSWLIVVVGVMTTMYAKIDPSLGIIAKIN
RTLETANCMSSQTKNVVSGVLFGTGLWVALIVTMRYSLKVLLSYHGWMFTEHGKMSRATKIWMGMVKIFSGRKPMLYSFQTSLPRLPVPA
VKDTVNRYLQSVRPLMKEEDFKRMTALAQDFAVGLGPRLQWYLKLKSWWATNYVSDWWEEYIYLRGRGPLMVNSNYYAMDLLYILPTHIQ
AARAGNAIHAILLYRRKLDREEIKPIRLLGSTIPLCSAQWERMFNTSRIPGEETDTIQHMRDSKHIVVYHRGRYFKVWLYHDGRLLKPRE
MEQQMQRILDNTSEPQPGEARLAALTAGDRVPWARCRQAYFGRGKNKQSLDAVEKAAFFVTLDETEEGYRSEDPDTSMDSYAKSLLHGRC
YDRWFDKSFTFVVFKNGKMGLNAEHSWADAPIVAHLWEYVMSIDSLQLGYAEDGHCKGDINPNIPYPTRLQWDIPGECQEVIETSLNTAN
LLANDVDFHSFPFVAFGKGIIKKCRTSPDAFVQLALQLAHYKVCRNQRCVSSSYLGYDCTTDKCNDRGVCNNKKHCHCSASYLPPDCSVQ

--------------------------------------------------------------

>19209_19209_12_CPT1A-ADAM2_CPT1A_chr11_68540733_ENST00000539743_ADAM2_chr8_39607263_ENST00000521880_length(amino acids)=718AA_BP=582
MKMAEAHQAVAFQFTVTPDGIDLRLSHEALRQIYLSGLHSWKKKFIRFKNGIITGVYPASPSSWLIVVVGVMTTMYAKIDPSLGIIAKIN
RTLETANCMSSQTKNVVSGVLFGTGLWVALIVTMRYSLKVLLSYHGWMFTEHGKMSRATKIWMGMVKIFSGRKPMLYSFQTSLPRLPVPA
VKDTVNRYLQSVRPLMKEEDFKRMTALAQDFAVGLGPRLQWYLKLKSWWATNYVSDWWEEYIYLRGRGPLMVNSNYYAMDLLYILPTHIQ
AARAGNAIHAILLYRRKLDREEIKPIRLLGSTIPLCSAQWERMFNTSRIPGEETDTIQHMRDSKHIVVYHRGRYFKVWLYHDGRLLKPRE
MEQQMQRILDNTSEPQPGEARLAALTAGDRVPWARCRQAYFGRGKNKQSLDAVEKAAFFVTLDETEEGYRSEDPDTSMDSYAKSLLHGRC
YDRWFDKSFTFVVFKNGKMGLNAEHSWADAPIVAHLWEYVMSIDSLQLGYAEDGHCKGDINPNIPYPTRLQWDIPGECQEVIETSLNTAN
LLANDVDFHSFPFVAFGKGIIKKCRTSPDAFVQLALQLAHYKVCRNQRCVSSSYLGYDCTTDKCNDRGVCNNKKHCHCSASYLPPDCSVQ

--------------------------------------------------------------

>19209_19209_13_CPT1A-ADAM2_CPT1A_chr11_68540733_ENST00000540367_ADAM2_chr8_39607263_ENST00000265708_length(amino acids)=718AA_BP=582
MKMAEAHQAVAFQFTVTPDGIDLRLSHEALRQIYLSGLHSWKKKFIRFKNGIITGVYPASPSSWLIVVVGVMTTMYAKIDPSLGIIAKIN
RTLETANCMSSQTKNVVSGVLFGTGLWVALIVTMRYSLKVLLSYHGWMFTEHGKMSRATKIWMGMVKIFSGRKPMLYSFQTSLPRLPVPA
VKDTVNRYLQSVRPLMKEEDFKRMTALAQDFAVGLGPRLQWYLKLKSWWATNYVSDWWEEYIYLRGRGPLMVNSNYYAMDLLYILPTHIQ
AARAGNAIHAILLYRRKLDREEIKPIRLLGSTIPLCSAQWERMFNTSRIPGEETDTIQHMRDSKHIVVYHRGRYFKVWLYHDGRLLKPRE
MEQQMQRILDNTSEPQPGEARLAALTAGDRVPWARCRQAYFGRGKNKQSLDAVEKAAFFVTLDETEEGYRSEDPDTSMDSYAKSLLHGRC
YDRWFDKSFTFVVFKNGKMGLNAEHSWADAPIVAHLWEYVMSIDSLQLGYAEDGHCKGDINPNIPYPTRLQWDIPGECQEVIETSLNTAN
LLANDVDFHSFPFVAFGKGIIKKCRTSPDAFVQLALQLAHYKVCRNQRCVSSSYLGYDCTTDKCNDRGVCNNKKHCHCSASYLPPDCSVQ

--------------------------------------------------------------

>19209_19209_14_CPT1A-ADAM2_CPT1A_chr11_68540733_ENST00000540367_ADAM2_chr8_39607263_ENST00000347580_length(amino acids)=718AA_BP=582
MKMAEAHQAVAFQFTVTPDGIDLRLSHEALRQIYLSGLHSWKKKFIRFKNGIITGVYPASPSSWLIVVVGVMTTMYAKIDPSLGIIAKIN
RTLETANCMSSQTKNVVSGVLFGTGLWVALIVTMRYSLKVLLSYHGWMFTEHGKMSRATKIWMGMVKIFSGRKPMLYSFQTSLPRLPVPA
VKDTVNRYLQSVRPLMKEEDFKRMTALAQDFAVGLGPRLQWYLKLKSWWATNYVSDWWEEYIYLRGRGPLMVNSNYYAMDLLYILPTHIQ
AARAGNAIHAILLYRRKLDREEIKPIRLLGSTIPLCSAQWERMFNTSRIPGEETDTIQHMRDSKHIVVYHRGRYFKVWLYHDGRLLKPRE
MEQQMQRILDNTSEPQPGEARLAALTAGDRVPWARCRQAYFGRGKNKQSLDAVEKAAFFVTLDETEEGYRSEDPDTSMDSYAKSLLHGRC
YDRWFDKSFTFVVFKNGKMGLNAEHSWADAPIVAHLWEYVMSIDSLQLGYAEDGHCKGDINPNIPYPTRLQWDIPGECQEVIETSLNTAN
LLANDVDFHSFPFVAFGKGIIKKCRTSPDAFVQLALQLAHYKVCRNQRCVSSSYLGYDCTTDKCNDRGVCNNKKHCHCSASYLPPDCSVQ

--------------------------------------------------------------

>19209_19209_15_CPT1A-ADAM2_CPT1A_chr11_68540733_ENST00000540367_ADAM2_chr8_39607263_ENST00000379853_length(amino acids)=718AA_BP=582
MKMAEAHQAVAFQFTVTPDGIDLRLSHEALRQIYLSGLHSWKKKFIRFKNGIITGVYPASPSSWLIVVVGVMTTMYAKIDPSLGIIAKIN
RTLETANCMSSQTKNVVSGVLFGTGLWVALIVTMRYSLKVLLSYHGWMFTEHGKMSRATKIWMGMVKIFSGRKPMLYSFQTSLPRLPVPA
VKDTVNRYLQSVRPLMKEEDFKRMTALAQDFAVGLGPRLQWYLKLKSWWATNYVSDWWEEYIYLRGRGPLMVNSNYYAMDLLYILPTHIQ
AARAGNAIHAILLYRRKLDREEIKPIRLLGSTIPLCSAQWERMFNTSRIPGEETDTIQHMRDSKHIVVYHRGRYFKVWLYHDGRLLKPRE
MEQQMQRILDNTSEPQPGEARLAALTAGDRVPWARCRQAYFGRGKNKQSLDAVEKAAFFVTLDETEEGYRSEDPDTSMDSYAKSLLHGRC
YDRWFDKSFTFVVFKNGKMGLNAEHSWADAPIVAHLWEYVMSIDSLQLGYAEDGHCKGDINPNIPYPTRLQWDIPGECQEVIETSLNTAN
LLANDVDFHSFPFVAFGKGIIKKCRTSPDAFVQLALQLAHYKVCRNQRCVSSSYLGYDCTTDKCNDRGVCNNKKHCHCSASYLPPDCSVQ

--------------------------------------------------------------

>19209_19209_16_CPT1A-ADAM2_CPT1A_chr11_68540733_ENST00000540367_ADAM2_chr8_39607263_ENST00000521880_length(amino acids)=718AA_BP=582
MKMAEAHQAVAFQFTVTPDGIDLRLSHEALRQIYLSGLHSWKKKFIRFKNGIITGVYPASPSSWLIVVVGVMTTMYAKIDPSLGIIAKIN
RTLETANCMSSQTKNVVSGVLFGTGLWVALIVTMRYSLKVLLSYHGWMFTEHGKMSRATKIWMGMVKIFSGRKPMLYSFQTSLPRLPVPA
VKDTVNRYLQSVRPLMKEEDFKRMTALAQDFAVGLGPRLQWYLKLKSWWATNYVSDWWEEYIYLRGRGPLMVNSNYYAMDLLYILPTHIQ
AARAGNAIHAILLYRRKLDREEIKPIRLLGSTIPLCSAQWERMFNTSRIPGEETDTIQHMRDSKHIVVYHRGRYFKVWLYHDGRLLKPRE
MEQQMQRILDNTSEPQPGEARLAALTAGDRVPWARCRQAYFGRGKNKQSLDAVEKAAFFVTLDETEEGYRSEDPDTSMDSYAKSLLHGRC
YDRWFDKSFTFVVFKNGKMGLNAEHSWADAPIVAHLWEYVMSIDSLQLGYAEDGHCKGDINPNIPYPTRLQWDIPGECQEVIETSLNTAN
LLANDVDFHSFPFVAFGKGIIKKCRTSPDAFVQLALQLAHYKVCRNQRCVSSSYLGYDCTTDKCNDRGVCNNKKHCHCSASYLPPDCSVQ

--------------------------------------------------------------

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Fusion Protein Functional Features


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr11:68540733/chr8:39607263)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
CPT1A

P50416

ADAM2

Q9UKF5

FUNCTION: Catalyzes the transfer of the acyl group of long-chain fatty acid-CoA conjugates onto carnitine, an essential step for the mitochondrial uptake of long-chain fatty acids and their subsequent beta-oxidation in the mitochondrion (PubMed:9691089, PubMed:11350182, PubMed:14517221). Plays an important role in hepatic triglyceride metabolism (By similarity). {ECO:0000250|UniProtKB:P32198, ECO:0000269|PubMed:11350182, ECO:0000269|PubMed:14517221, ECO:0000269|PubMed:9691089}.FUNCTION: May be involved in spermatogenesis and fertilization. Seems to be a non catalytic metalloprotease-like protein.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

* Minus value of BPloci means that the break pointn is located before the CDS.
- Retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCPT1Achr11:68540732chr8:39607263ENST00000265641-1419555_567580.0774.0RegionCoenzyme A binding
HgeneCPT1Achr11:68540732chr8:39607263ENST00000376618-1419555_567580.0757.0RegionCoenzyme A binding
HgeneCPT1Achr11:68540732chr8:39607263ENST00000539743-1318555_567580.0774.0RegionCoenzyme A binding
HgeneCPT1Achr11:68540732chr8:39607263ENST00000540367-1318555_567580.0757.0RegionCoenzyme A binding
HgeneCPT1Achr11:68540733chr8:39607263ENST00000265641-1419555_567580.0774.0RegionCoenzyme A binding
HgeneCPT1Achr11:68540733chr8:39607263ENST00000376618-1419555_567580.0757.0RegionCoenzyme A binding
HgeneCPT1Achr11:68540733chr8:39607263ENST00000539743-1318555_567580.0774.0RegionCoenzyme A binding
HgeneCPT1Achr11:68540733chr8:39607263ENST00000540367-1318555_567580.0757.0RegionCoenzyme A binding
HgeneCPT1Achr11:68540732chr8:39607263ENST00000265641-14192_47580.0774.0Topological domainCytoplasmic
HgeneCPT1Achr11:68540732chr8:39607263ENST00000265641-141974_102580.0774.0Topological domainMitochondrial intermembrane
HgeneCPT1Achr11:68540732chr8:39607263ENST00000376618-14192_47580.0757.0Topological domainCytoplasmic
HgeneCPT1Achr11:68540732chr8:39607263ENST00000376618-141974_102580.0757.0Topological domainMitochondrial intermembrane
HgeneCPT1Achr11:68540732chr8:39607263ENST00000539743-13182_47580.0774.0Topological domainCytoplasmic
HgeneCPT1Achr11:68540732chr8:39607263ENST00000539743-131874_102580.0774.0Topological domainMitochondrial intermembrane
HgeneCPT1Achr11:68540732chr8:39607263ENST00000540367-13182_47580.0757.0Topological domainCytoplasmic
HgeneCPT1Achr11:68540732chr8:39607263ENST00000540367-131874_102580.0757.0Topological domainMitochondrial intermembrane
HgeneCPT1Achr11:68540733chr8:39607263ENST00000265641-14192_47580.0774.0Topological domainCytoplasmic
HgeneCPT1Achr11:68540733chr8:39607263ENST00000265641-141974_102580.0774.0Topological domainMitochondrial intermembrane
HgeneCPT1Achr11:68540733chr8:39607263ENST00000376618-14192_47580.0757.0Topological domainCytoplasmic
HgeneCPT1Achr11:68540733chr8:39607263ENST00000376618-141974_102580.0757.0Topological domainMitochondrial intermembrane
HgeneCPT1Achr11:68540733chr8:39607263ENST00000539743-13182_47580.0774.0Topological domainCytoplasmic
HgeneCPT1Achr11:68540733chr8:39607263ENST00000539743-131874_102580.0774.0Topological domainMitochondrial intermembrane
HgeneCPT1Achr11:68540733chr8:39607263ENST00000540367-13182_47580.0757.0Topological domainCytoplasmic
HgeneCPT1Achr11:68540733chr8:39607263ENST00000540367-131874_102580.0757.0Topological domainMitochondrial intermembrane
HgeneCPT1Achr11:68540732chr8:39607263ENST00000265641-1419103_122580.0774.0TransmembraneHelical
HgeneCPT1Achr11:68540732chr8:39607263ENST00000265641-141948_73580.0774.0TransmembraneHelical
HgeneCPT1Achr11:68540732chr8:39607263ENST00000376618-1419103_122580.0757.0TransmembraneHelical
HgeneCPT1Achr11:68540732chr8:39607263ENST00000376618-141948_73580.0757.0TransmembraneHelical
HgeneCPT1Achr11:68540732chr8:39607263ENST00000539743-1318103_122580.0774.0TransmembraneHelical
HgeneCPT1Achr11:68540732chr8:39607263ENST00000539743-131848_73580.0774.0TransmembraneHelical
HgeneCPT1Achr11:68540732chr8:39607263ENST00000540367-1318103_122580.0757.0TransmembraneHelical
HgeneCPT1Achr11:68540732chr8:39607263ENST00000540367-131848_73580.0757.0TransmembraneHelical
HgeneCPT1Achr11:68540733chr8:39607263ENST00000265641-1419103_122580.0774.0TransmembraneHelical
HgeneCPT1Achr11:68540733chr8:39607263ENST00000265641-141948_73580.0774.0TransmembraneHelical
HgeneCPT1Achr11:68540733chr8:39607263ENST00000376618-1419103_122580.0757.0TransmembraneHelical
HgeneCPT1Achr11:68540733chr8:39607263ENST00000376618-141948_73580.0757.0TransmembraneHelical
HgeneCPT1Achr11:68540733chr8:39607263ENST00000539743-1318103_122580.0774.0TransmembraneHelical
HgeneCPT1Achr11:68540733chr8:39607263ENST00000539743-131848_73580.0774.0TransmembraneHelical
HgeneCPT1Achr11:68540733chr8:39607263ENST00000540367-1318103_122580.0757.0TransmembraneHelical
HgeneCPT1Achr11:68540733chr8:39607263ENST00000540367-131848_73580.0757.0TransmembraneHelical
TgeneADAM2chr11:68540732chr8:39607263ENST000002657081521612_645599.0788.6666666666666DomainNote=EGF-like
TgeneADAM2chr11:68540732chr8:39607263ENST000003475801420612_645580.0796.3333333333334DomainNote=EGF-like
TgeneADAM2chr11:68540733chr8:39607263ENST000002657081521612_645599.0788.6666666666666DomainNote=EGF-like
TgeneADAM2chr11:68540733chr8:39607263ENST000003475801420612_645580.0796.3333333333334DomainNote=EGF-like
TgeneADAM2chr11:68540732chr8:39607263ENST000002657081521708_735599.0788.6666666666666Topological domainCytoplasmic
TgeneADAM2chr11:68540732chr8:39607263ENST000003475801420708_735580.0796.3333333333334Topological domainCytoplasmic
TgeneADAM2chr11:68540733chr8:39607263ENST000002657081521708_735599.0788.6666666666666Topological domainCytoplasmic
TgeneADAM2chr11:68540733chr8:39607263ENST000003475801420708_735580.0796.3333333333334Topological domainCytoplasmic
TgeneADAM2chr11:68540732chr8:39607263ENST000002657081521687_707599.0788.6666666666666TransmembraneHelical
TgeneADAM2chr11:68540732chr8:39607263ENST000003475801420687_707580.0796.3333333333334TransmembraneHelical
TgeneADAM2chr11:68540733chr8:39607263ENST000002657081521687_707599.0788.6666666666666TransmembraneHelical
TgeneADAM2chr11:68540733chr8:39607263ENST000003475801420687_707580.0796.3333333333334TransmembraneHelical

- Not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCPT1Achr11:68540732chr8:39607263ENST00000265641-1419123_773580.0774.0Topological domainCytoplasmic
HgeneCPT1Achr11:68540732chr8:39607263ENST00000376618-1419123_773580.0757.0Topological domainCytoplasmic
HgeneCPT1Achr11:68540732chr8:39607263ENST00000539743-1318123_773580.0774.0Topological domainCytoplasmic
HgeneCPT1Achr11:68540732chr8:39607263ENST00000540367-1318123_773580.0757.0Topological domainCytoplasmic
HgeneCPT1Achr11:68540733chr8:39607263ENST00000265641-1419123_773580.0774.0Topological domainCytoplasmic
HgeneCPT1Achr11:68540733chr8:39607263ENST00000376618-1419123_773580.0757.0Topological domainCytoplasmic
HgeneCPT1Achr11:68540733chr8:39607263ENST00000539743-1318123_773580.0774.0Topological domainCytoplasmic
HgeneCPT1Achr11:68540733chr8:39607263ENST00000540367-1318123_773580.0757.0Topological domainCytoplasmic
TgeneADAM2chr11:68540732chr8:39607263ENST000002657081521477_606599.0788.6666666666666Compositional biasNote=Cys-rich
TgeneADAM2chr11:68540732chr8:39607263ENST000003475801420477_606580.0796.3333333333334Compositional biasNote=Cys-rich
TgeneADAM2chr11:68540733chr8:39607263ENST000002657081521477_606599.0788.6666666666666Compositional biasNote=Cys-rich
TgeneADAM2chr11:68540733chr8:39607263ENST000003475801420477_606580.0796.3333333333334Compositional biasNote=Cys-rich
TgeneADAM2chr11:68540732chr8:39607263ENST000002657081521178_375599.0788.6666666666666DomainPeptidase M12B
TgeneADAM2chr11:68540732chr8:39607263ENST000002657081521384_473599.0788.6666666666666DomainDisintegrin
TgeneADAM2chr11:68540732chr8:39607263ENST000003475801420178_375580.0796.3333333333334DomainPeptidase M12B
TgeneADAM2chr11:68540732chr8:39607263ENST000003475801420384_473580.0796.3333333333334DomainDisintegrin
TgeneADAM2chr11:68540733chr8:39607263ENST000002657081521178_375599.0788.6666666666666DomainPeptidase M12B
TgeneADAM2chr11:68540733chr8:39607263ENST000002657081521384_473599.0788.6666666666666DomainDisintegrin
TgeneADAM2chr11:68540733chr8:39607263ENST000003475801420178_375580.0796.3333333333334DomainPeptidase M12B
TgeneADAM2chr11:68540733chr8:39607263ENST000003475801420384_473580.0796.3333333333334DomainDisintegrin
TgeneADAM2chr11:68540732chr8:39607263ENST000002657081521175_686599.0788.6666666666666Topological domainExtracellular
TgeneADAM2chr11:68540732chr8:39607263ENST000003475801420175_686580.0796.3333333333334Topological domainExtracellular
TgeneADAM2chr11:68540733chr8:39607263ENST000002657081521175_686599.0788.6666666666666Topological domainExtracellular
TgeneADAM2chr11:68540733chr8:39607263ENST000003475801420175_686580.0796.3333333333334Topological domainExtracellular


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Fusion Protein-Protein Interaction


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type from validated records (BIOGRID-3.4.160)
GenePPI interactors


check button Protein-protein interactors based on sequence similarity (STRING)
GeneSTRING network
CPT1A
ADAM2


check button - Retained interactions in fusion protein (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost interactions due to fusion (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs to CPT1A-ADAM2


check button Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDrugSourcePMID

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Related Diseases to CPT1A-ADAM2


check button Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDiseaseSourcePMID

check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource