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	Fusion Gene Summary
	Fusion Gene Sample Information
	Fusion ORF Analysis
	Fusion Amino Acid Sequences
	Fusion Protein Functional Features
	Fusion Protein Structure
	pLDDT scores
	Ramachandran Plot of Fusion Protein Structure
	Fusion Protein-Protein Interaction
	Related drugs with this fusion protein
	Related disease with this fusion protein

Fusion Protein:ADK-KCNMA1

Fusion Protein Summary

Fusion gene summary

Fusion partner gene information	Fusion gene name: ADK-KCNMA1
	FusionPDB ID: 2469
	FusionGDB2.0 ID: 2469
		Hgene	Tgene
	Gene symbol	ADK	KCNMA1
	Gene ID	132	3778
	Gene name	adenosine kinase	potassium calcium-activated channel subfamily M alpha 1
	Synonyms	AK	BKTM\|CADEDS\|IEG16\|KCa1.1\|LIWAS\|MaxiK\|PNKD3\|SAKCA\|SLO\|SLO-ALPHA\|SLO1\|bA205K10.1\|hSlo\|mSLO1
	Cytomap	10q22.2\|10q11-q24	10q22.3
	Type of gene	protein-coding	protein-coding
	Description	adenosine kinaseadenosine 5'-phosphotransferasetesticular tissue protein Li 14	calcium-activated potassium channel subunit alpha-1uncharacterized proteinBK channel alpha subunitBKCA alpha subunitbig potassium channel alpha subunitcalcium-activated potassium channel, subfamily M subunit alpha-1k(VCA)alphamaxi-K channel HSLOpo
	Modification date	20200313	20200315
	UniProtAcc	P55263	Q12791
Ensembl transtripts involved in fusion gene	ENST ids	ENST00000286621, ENST00000372734, ENST00000539909, ENST00000541550, ENST00000467840,	ENST00000480683, ENST00000481070, ENST00000484507, ENST00000286627, ENST00000286628, ENST00000354353, ENST00000372440, ENST00000372443, ENST00000404771, ENST00000404857, ENST00000406533,
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)	* DoF score	19 X 13 X 10=2470	18 X 17 X 8=2448
	# samples	26	21
	** MAII score	log2(26/2470*10)=-3.24792751344359 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(21/2448*10)=-3.54314232502653 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context (manual curation of fusion genes in FusionPDB)	PubMed: ADK [Title/Abstract] AND KCNMA1 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)	ADK(76074503)-KCNMA1(79011014), # samples:4
Anticipated loss of major functional domain due to fusion event.	ADK-KCNMA1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. ADK-KCNMA1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. ADK-KCNMA1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. ADK-KCNMA1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Tgene	KCNMA1	GO:0001666	response to hypoxia	15528406
Tgene	KCNMA1	GO:0006813	potassium ion transport	7573516\|7877450\|11245614\|12388065\|17706472\|18458941
Tgene	KCNMA1	GO:0006970	response to osmotic stress	10840032\|12388065
Tgene	KCNMA1	GO:0030007	cellular potassium ion homeostasis	11245614
Tgene	KCNMA1	GO:0034465	response to carbon monoxide	15528406
Tgene	KCNMA1	GO:0042391	regulation of membrane potential	7877450\|7993625
Tgene	KCNMA1	GO:0045794	negative regulation of cell volume	12388065
Tgene	KCNMA1	GO:0051592	response to calcium ion	12388065\|18458941
Tgene	KCNMA1	GO:0060073	micturition	11641143
Tgene	KCNMA1	GO:0060083	smooth muscle contraction involved in micturition	11641143

Fusion gene breakpoints across ADK (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across KCNMA1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

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Fusion Gene Sample Information

Fusion gene information from FusionGDB2.0.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	BRCA	TCGA-AN-A0AJ-01A	ADK	chr10	76074503	-	KCNMA1	chr10	79011014	-
ChimerDB4	BRCA	TCGA-AN-A0AJ-01A	ADK	chr10	76074503	+	KCNMA1	chr10	79011014	-
ChimerDB4	BRCA	TCGA-AN-A0AJ	ADK	chr10	76074503	+	KCNMA1	chr10	79011014	-
ChimerDB4	PRAD	TCGA-KK-A8IH-01A	ADK	chr10	75984349	-	KCNMA1	chr10	78778857	-
ChimerDB4	PRAD	TCGA-KK-A8IH-01A	ADK	chr10	75984349	+	KCNMA1	chr10	78778857	-

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Fusion ORF Analysis

Fusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000539909	ADK	chr10	76074503	+	ENST00000404771	KCNMA1	chr10	79011014	-	3819	350	77	3676	1199
ENST00000539909	ADK	chr10	76074503	+	ENST00000372440	KCNMA1	chr10	79011014	-	3616	350	77	3343	1088
ENST00000539909	ADK	chr10	76074503	+	ENST00000372443	KCNMA1	chr10	79011014	-	3700	350	77	3427	1116
ENST00000539909	ADK	chr10	76074503	+	ENST00000286628	KCNMA1	chr10	79011014	-	5906	350	77	3520	1147
ENST00000539909	ADK	chr10	76074503	+	ENST00000286627	KCNMA1	chr10	79011014	-	5732	350	77	3346	1089
ENST00000539909	ADK	chr10	76074503	+	ENST00000354353	KCNMA1	chr10	79011014	-	3530	350	77	3529	1151
ENST00000539909	ADK	chr10	76074503	+	ENST00000404857	KCNMA1	chr10	79011014	-	3470	350	77	3469	1131
ENST00000539909	ADK	chr10	76074503	+	ENST00000406533	KCNMA1	chr10	79011014	-	3533	350	77	3532	1152
ENST00000286621	ADK	chr10	76074503	+	ENST00000404771	KCNMA1	chr10	79011014	-	3792	323	50	3649	1199
ENST00000286621	ADK	chr10	76074503	+	ENST00000372440	KCNMA1	chr10	79011014	-	3589	323	50	3316	1088
ENST00000286621	ADK	chr10	76074503	+	ENST00000372443	KCNMA1	chr10	79011014	-	3673	323	50	3400	1116
ENST00000286621	ADK	chr10	76074503	+	ENST00000286628	KCNMA1	chr10	79011014	-	5879	323	50	3493	1147
ENST00000286621	ADK	chr10	76074503	+	ENST00000286627	KCNMA1	chr10	79011014	-	5705	323	50	3319	1089
ENST00000286621	ADK	chr10	76074503	+	ENST00000354353	KCNMA1	chr10	79011014	-	3503	323	50	3502	1151
ENST00000286621	ADK	chr10	76074503	+	ENST00000404857	KCNMA1	chr10	79011014	-	3443	323	50	3442	1131
ENST00000286621	ADK	chr10	76074503	+	ENST00000406533	KCNMA1	chr10	79011014	-	3506	323	50	3505	1152
ENST00000372734	ADK	chr10	76074503	+	ENST00000404771	KCNMA1	chr10	79011014	-	3878	409	187	3735	1182
ENST00000372734	ADK	chr10	76074503	+	ENST00000372440	KCNMA1	chr10	79011014	-	3675	409	187	3402	1071
ENST00000372734	ADK	chr10	76074503	+	ENST00000372443	KCNMA1	chr10	79011014	-	3759	409	187	3486	1099
ENST00000372734	ADK	chr10	76074503	+	ENST00000286628	KCNMA1	chr10	79011014	-	5965	409	187	3579	1130
ENST00000372734	ADK	chr10	76074503	+	ENST00000286627	KCNMA1	chr10	79011014	-	5791	409	187	3405	1072
ENST00000372734	ADK	chr10	76074503	+	ENST00000354353	KCNMA1	chr10	79011014	-	3589	409	187	3588	1134
ENST00000372734	ADK	chr10	76074503	+	ENST00000404857	KCNMA1	chr10	79011014	-	3529	409	187	3528	1114
ENST00000372734	ADK	chr10	76074503	+	ENST00000406533	KCNMA1	chr10	79011014	-	3592	409	187	3591	1135
ENST00000541550	ADK	chr10	76074503	+	ENST00000404771	KCNMA1	chr10	79011014	-	3747	278	110	3604	1164
ENST00000541550	ADK	chr10	76074503	+	ENST00000372440	KCNMA1	chr10	79011014	-	3544	278	110	3271	1053
ENST00000541550	ADK	chr10	76074503	+	ENST00000372443	KCNMA1	chr10	79011014	-	3628	278	110	3355	1081
ENST00000541550	ADK	chr10	76074503	+	ENST00000286628	KCNMA1	chr10	79011014	-	5834	278	110	3448	1112
ENST00000541550	ADK	chr10	76074503	+	ENST00000286627	KCNMA1	chr10	79011014	-	5660	278	110	3274	1054
ENST00000541550	ADK	chr10	76074503	+	ENST00000354353	KCNMA1	chr10	79011014	-	3458	278	110	3457	1116
ENST00000541550	ADK	chr10	76074503	+	ENST00000404857	KCNMA1	chr10	79011014	-	3398	278	110	3397	1096
ENST00000541550	ADK	chr10	76074503	+	ENST00000406533	KCNMA1	chr10	79011014	-	3461	278	110	3460	1117
ENST00000539909	ADK	chr10	75984349	+	ENST00000404771	KCNMA1	chr10	78778857	-	2352	271	77	2209	710
ENST00000539909	ADK	chr10	75984349	+	ENST00000372440	KCNMA1	chr10	78778857	-	2149	271	77	1876	599
ENST00000539909	ADK	chr10	75984349	+	ENST00000372443	KCNMA1	chr10	78778857	-	2233	271	77	1960	627
ENST00000539909	ADK	chr10	75984349	+	ENST00000286628	KCNMA1	chr10	78778857	-	4439	271	77	2053	658
ENST00000539909	ADK	chr10	75984349	+	ENST00000286627	KCNMA1	chr10	78778857	-	4265	271	77	1879	600
ENST00000539909	ADK	chr10	75984349	+	ENST00000354353	KCNMA1	chr10	78778857	-	2063	271	77	2062	662
ENST00000539909	ADK	chr10	75984349	+	ENST00000404857	KCNMA1	chr10	78778857	-	2003	271	77	2002	642
ENST00000539909	ADK	chr10	75984349	+	ENST00000406533	KCNMA1	chr10	78778857	-	2057	271	77	2056	660
ENST00000286621	ADK	chr10	75984349	+	ENST00000404771	KCNMA1	chr10	78778857	-	2325	244	50	2182	710
ENST00000286621	ADK	chr10	75984349	+	ENST00000372440	KCNMA1	chr10	78778857	-	2122	244	50	1849	599
ENST00000286621	ADK	chr10	75984349	+	ENST00000372443	KCNMA1	chr10	78778857	-	2206	244	50	1933	627
ENST00000286621	ADK	chr10	75984349	+	ENST00000286628	KCNMA1	chr10	78778857	-	4412	244	50	2026	658
ENST00000286621	ADK	chr10	75984349	+	ENST00000286627	KCNMA1	chr10	78778857	-	4238	244	50	1852	600
ENST00000286621	ADK	chr10	75984349	+	ENST00000354353	KCNMA1	chr10	78778857	-	2036	244	50	2035	662
ENST00000286621	ADK	chr10	75984349	+	ENST00000404857	KCNMA1	chr10	78778857	-	1976	244	50	1975	642
ENST00000286621	ADK	chr10	75984349	+	ENST00000406533	KCNMA1	chr10	78778857	-	2030	244	50	2029	660
ENST00000372734	ADK	chr10	75984349	+	ENST00000404771	KCNMA1	chr10	78778857	-	2411	330	187	2268	693
ENST00000372734	ADK	chr10	75984349	+	ENST00000372440	KCNMA1	chr10	78778857	-	2208	330	187	1935	582
ENST00000372734	ADK	chr10	75984349	+	ENST00000372443	KCNMA1	chr10	78778857	-	2292	330	187	2019	610
ENST00000372734	ADK	chr10	75984349	+	ENST00000286628	KCNMA1	chr10	78778857	-	4498	330	187	2112	641
ENST00000372734	ADK	chr10	75984349	+	ENST00000286627	KCNMA1	chr10	78778857	-	4324	330	187	1938	583
ENST00000372734	ADK	chr10	75984349	+	ENST00000354353	KCNMA1	chr10	78778857	-	2122	330	187	2121	645
ENST00000372734	ADK	chr10	75984349	+	ENST00000404857	KCNMA1	chr10	78778857	-	2062	330	187	2061	625
ENST00000372734	ADK	chr10	75984349	+	ENST00000406533	KCNMA1	chr10	78778857	-	2116	330	187	2115	643

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000539909	ENST00000404771	ADK	chr10	76074503	+	KCNMA1	chr10	79011014	-	0.000820479	0.99917954
ENST00000539909	ENST00000372440	ADK	chr10	76074503	+	KCNMA1	chr10	79011014	-	0.001004084	0.99899596
ENST00000539909	ENST00000372443	ADK	chr10	76074503	+	KCNMA1	chr10	79011014	-	0.000635957	0.9993641
ENST00000539909	ENST00000286628	ADK	chr10	76074503	+	KCNMA1	chr10	79011014	-	0.000474308	0.99952567
ENST00000539909	ENST00000286627	ADK	chr10	76074503	+	KCNMA1	chr10	79011014	-	0.000321961	0.999678
ENST00000539909	ENST00000354353	ADK	chr10	76074503	+	KCNMA1	chr10	79011014	-	0.001181522	0.99881846
ENST00000539909	ENST00000404857	ADK	chr10	76074503	+	KCNMA1	chr10	79011014	-	0.000745804	0.99925417
ENST00000539909	ENST00000406533	ADK	chr10	76074503	+	KCNMA1	chr10	79011014	-	0.000762246	0.9992378
ENST00000286621	ENST00000404771	ADK	chr10	76074503	+	KCNMA1	chr10	79011014	-	0.00080325	0.9991967
ENST00000286621	ENST00000372440	ADK	chr10	76074503	+	KCNMA1	chr10	79011014	-	0.000984928	0.9990151
ENST00000286621	ENST00000372443	ADK	chr10	76074503	+	KCNMA1	chr10	79011014	-	0.000625499	0.99937457
ENST00000286621	ENST00000286628	ADK	chr10	76074503	+	KCNMA1	chr10	79011014	-	0.000459241	0.9995408
ENST00000286621	ENST00000286627	ADK	chr10	76074503	+	KCNMA1	chr10	79011014	-	0.000311897	0.99968815
ENST00000286621	ENST00000354353	ADK	chr10	76074503	+	KCNMA1	chr10	79011014	-	0.001158982	0.998841
ENST00000286621	ENST00000404857	ADK	chr10	76074503	+	KCNMA1	chr10	79011014	-	0.000733953	0.9992661
ENST00000286621	ENST00000406533	ADK	chr10	76074503	+	KCNMA1	chr10	79011014	-	0.000748573	0.9992514
ENST00000372734	ENST00000404771	ADK	chr10	76074503	+	KCNMA1	chr10	79011014	-	0.000939727	0.99906033
ENST00000372734	ENST00000372440	ADK	chr10	76074503	+	KCNMA1	chr10	79011014	-	0.001132965	0.99886703
ENST00000372734	ENST00000372443	ADK	chr10	76074503	+	KCNMA1	chr10	79011014	-	0.000746156	0.9992538
ENST00000372734	ENST00000286628	ADK	chr10	76074503	+	KCNMA1	chr10	79011014	-	0.000553707	0.99944633
ENST00000372734	ENST00000286627	ADK	chr10	76074503	+	KCNMA1	chr10	79011014	-	0.000371251	0.9996288
ENST00000372734	ENST00000354353	ADK	chr10	76074503	+	KCNMA1	chr10	79011014	-	0.001374299	0.99862576
ENST00000372734	ENST00000404857	ADK	chr10	76074503	+	KCNMA1	chr10	79011014	-	0.00085089	0.9991491
ENST00000372734	ENST00000406533	ADK	chr10	76074503	+	KCNMA1	chr10	79011014	-	0.000886749	0.99911326
ENST00000541550	ENST00000404771	ADK	chr10	76074503	+	KCNMA1	chr10	79011014	-	0.000823845	0.9991761
ENST00000541550	ENST00000372440	ADK	chr10	76074503	+	KCNMA1	chr10	79011014	-	0.001003245	0.9989968
ENST00000541550	ENST00000372443	ADK	chr10	76074503	+	KCNMA1	chr10	79011014	-	0.000655578	0.9993444
ENST00000541550	ENST00000286628	ADK	chr10	76074503	+	KCNMA1	chr10	79011014	-	0.000484718	0.9995153
ENST00000541550	ENST00000286627	ADK	chr10	76074503	+	KCNMA1	chr10	79011014	-	0.000322127	0.9996779
ENST00000541550	ENST00000354353	ADK	chr10	76074503	+	KCNMA1	chr10	79011014	-	0.001207895	0.9987921
ENST00000541550	ENST00000404857	ADK	chr10	76074503	+	KCNMA1	chr10	79011014	-	0.000756278	0.99924374
ENST00000541550	ENST00000406533	ADK	chr10	76074503	+	KCNMA1	chr10	79011014	-	0.000781087	0.99921894
ENST00000539909	ENST00000404771	ADK	chr10	75984349	+	KCNMA1	chr10	78778857	-	0.0044046	0.9955954
ENST00000539909	ENST00000372440	ADK	chr10	75984349	+	KCNMA1	chr10	78778857	-	0.004854245	0.99514574
ENST00000539909	ENST00000372443	ADK	chr10	75984349	+	KCNMA1	chr10	78778857	-	0.005098263	0.9949018
ENST00000539909	ENST00000286628	ADK	chr10	75984349	+	KCNMA1	chr10	78778857	-	0.001237278	0.9987627
ENST00000539909	ENST00000286627	ADK	chr10	75984349	+	KCNMA1	chr10	78778857	-	0.001310685	0.99868935
ENST00000539909	ENST00000354353	ADK	chr10	75984349	+	KCNMA1	chr10	78778857	-	0.006136577	0.99386346
ENST00000539909	ENST00000404857	ADK	chr10	75984349	+	KCNMA1	chr10	78778857	-	0.004847314	0.9951527
ENST00000539909	ENST00000406533	ADK	chr10	75984349	+	KCNMA1	chr10	78778857	-	0.004601857	0.9953981
ENST00000286621	ENST00000404771	ADK	chr10	75984349	+	KCNMA1	chr10	78778857	-	0.004318178	0.99568176
ENST00000286621	ENST00000372440	ADK	chr10	75984349	+	KCNMA1	chr10	78778857	-	0.004682873	0.9953171
ENST00000286621	ENST00000372443	ADK	chr10	75984349	+	KCNMA1	chr10	78778857	-	0.004957539	0.99504244
ENST00000286621	ENST00000286628	ADK	chr10	75984349	+	KCNMA1	chr10	78778857	-	0.001220216	0.99877983
ENST00000286621	ENST00000286627	ADK	chr10	75984349	+	KCNMA1	chr10	78778857	-	0.001278426	0.99872154
ENST00000286621	ENST00000354353	ADK	chr10	75984349	+	KCNMA1	chr10	78778857	-	0.006035387	0.9939646
ENST00000286621	ENST00000404857	ADK	chr10	75984349	+	KCNMA1	chr10	78778857	-	0.00457009	0.9954299
ENST00000286621	ENST00000406533	ADK	chr10	75984349	+	KCNMA1	chr10	78778857	-	0.004507986	0.995492
ENST00000372734	ENST00000404771	ADK	chr10	75984349	+	KCNMA1	chr10	78778857	-	0.002067748	0.9979323
ENST00000372734	ENST00000372440	ADK	chr10	75984349	+	KCNMA1	chr10	78778857	-	0.002094038	0.99790597
ENST00000372734	ENST00000372443	ADK	chr10	75984349	+	KCNMA1	chr10	78778857	-	0.002418425	0.9975816
ENST00000372734	ENST00000286628	ADK	chr10	75984349	+	KCNMA1	chr10	78778857	-	0.000498989	0.999501
ENST00000372734	ENST00000286627	ADK	chr10	75984349	+	KCNMA1	chr10	78778857	-	0.000563125	0.9994369
ENST00000372734	ENST00000354353	ADK	chr10	75984349	+	KCNMA1	chr10	78778857	-	0.002692694	0.9973073
ENST00000372734	ENST00000404857	ADK	chr10	75984349	+	KCNMA1	chr10	78778857	-	0.003143517	0.99685645
ENST00000372734	ENST00000406533	ADK	chr10	75984349	+	KCNMA1	chr10	78778857	-	0.003870735	0.9961293

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Fusion Amino Acid Sequences

For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

>2469_2469_1_ADK-KCNMA1_ADK_chr10_75984349_ENST00000286621_KCNMA1_chr10_78778857_ENST00000286627_length(amino acids)=600AA_BP=65
MAAAEEEPKPKKLKVEAPQALRENILFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELILINPGNHLKIQEGTLGFFIASDAK
EVKRAFFYCKACHDDITDPKRIKKCGCKRLEDEQPSTLSPKKKQRNGGMRNSPNTSPKLMRHDPLLIPGNDQIDNMDSNVKKYDSTGMFH
WCAPKEIEKVILTRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLVMPLRASNFHYHELKHIVFVGSIEYLKREWETLHNFPKVSILPGTP
LSRADLRAVNINLCDMCVILSANQNNIDDTSLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTG
VNIPIITELVNDTNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGY
STPQTLANRDRCRVAQLALLDGPFADLGDGGCYGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLIFCLM

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>2469_2469_2_ADK-KCNMA1_ADK_chr10_75984349_ENST00000286621_KCNMA1_chr10_78778857_ENST00000286628_length(amino acids)=658AA_BP=65
MAAAEEEPKPKKLKVEAPQALRENILFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELILINPGNHLKIQEGTLGFFIASDAK
EVKRAFFYCKACHDDITDPKRIKKCGCKRPKMSIYKRMRRACCFDCGRSERDCSCMSGRVRGNVDTLERAFPLSSVSVNDCSTSFRAFED
EQPSTLSPKKKQRNGGMRNSPNTSPKLMRHDPLLIPGNDQIDNMDSNVKKYDSTGMFHWCAPKEIEKVILTRSEAAMTVLSGHVVVCIFG
DVSSALIGLRNLVMPLRASNFHYHELKHIVFVGSIEYLKREWETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSANQNNIDDTSL
QDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTGVNIPIITELVNDTNVQFLDQDDDDDPDTELYL
TQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRDRCRVAQLALLDGPFADLGDGGC
YGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLIFCLMQFDHNAGQSRASLSHSSHSSQSSSKKSSSVHS

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>2469_2469_3_ADK-KCNMA1_ADK_chr10_75984349_ENST00000286621_KCNMA1_chr10_78778857_ENST00000354353_length(amino acids)=662AA_BP=65
MAAAEEEPKPKKLKVEAPQALRENILFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELILINPGNHLKIQEGTLGFFIASDAK
EVKRAFFYCKACHDDITDPKRIKKCGCKRRWEEHCSLWRLESKGNVRRLNYCRGQQTFSVKVKVAARSRYSKDPFEFKKETPNSRLVTEP
VEDEQPSTLSPKKKQRNGGMRNSPNTSPKLMRHDPLLIPGNDQIDNMDSNVKKYDSTGMFHWCAPKEIEKVILTRSEAAMTVLSGHVVVC
IFGDVSSALIGLRNLVMPLRASNFHYHELKHIVFVGSIEYLKREWETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSANQNNIDD
TSLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTGVNIPIITELVNDTNVQFLDQDDDDDPDTE
LYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRDRCRVAQLALLDGPFADLGD
GGCYGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLIFCLMQFDHNAGQSRASLSHSSHSSQSSSKKSSS

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>2469_2469_4_ADK-KCNMA1_ADK_chr10_75984349_ENST00000286621_KCNMA1_chr10_78778857_ENST00000372440_length(amino acids)=599AA_BP=65
MAAAEEEPKPKKLKVEAPQALRENILFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELILINPGNHLKIQEGTLGFFIASDAK
EVKRAFFYCKACHDDITDPKRIKKCGCKRLEDEQPSTLSPKKKQRNGGMRNSPNTSPKLMRHDPLLIPGNDQIDNMDSNVKKYDSTGMFH
WCAPKEIEKVILTRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLVMPLRASNFHYHELKHIVFVGSIEYLKREWETLHNFPKVSILPGTP
LSRADLRAVNINLCDMCVILSANQNNIDDTSLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTG
VNIPIITELVNDTNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGY
STPQTLANRDRCRVAQLALLDGPFADLGDGGCYGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLIFCLM

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>2469_2469_5_ADK-KCNMA1_ADK_chr10_75984349_ENST00000286621_KCNMA1_chr10_78778857_ENST00000372443_length(amino acids)=627AA_BP=65
MAAAEEEPKPKKLKVEAPQALRENILFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELILINPGNHLKIQEGTLGFFIASDAK
EVKRAFFYCKACHDDITDPKRIKKCGCKRLEDEQPSTLSPKKKQRNGGMRNSPNTSPKLMRHDPLLIPGNDQIDNMDSNVKKYDSTGMFH
WCAPKEIEKVILTRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLVMPLRASNFHYHELKHIVFVGSIEYLKREWETLHNFPKVSILPGTP
LSRADLRAVNINLCDMCVILSANQNNIDDTSLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTG
VNIPIITELAKPGKLPLVSVNQEKNSGTHILMITELVNDTNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTL
IRTLVTGGATPELEALIAEENALRGGYSTPQTLANRDRCRVAQLALLDGPFADLGDGGCYGDLFCKALKTYNMLCFGIYRLRDAHLSTPS

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>2469_2469_6_ADK-KCNMA1_ADK_chr10_75984349_ENST00000286621_KCNMA1_chr10_78778857_ENST00000404771_length(amino acids)=710AA_BP=65
MAAAEEEPKPKKLKVEAPQALRENILFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELILINPGNHLKIQEGTLGFFIASDAK
EVKRAFFYCKACHDDITDPKRIKKCGCKRPKMSIYKRMRRACCFDCGRSERDCSCMSGRVRGNVDTLERAFPLSSVSVNDCSTSFRAFED
EQPSTLSPKKKQRNGGMRNSPNTSPKLMRHDPLLIPGNDQIDNMDSNVKKYDSTGMFHWCAPKEIEKVILTRSEAAMTVLSGHVVVCIFG
DVSSALIGLRNLVMPLRASNFHYHELKHIVFVGSIEYLKREWETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSANQNNIDDTSL
QDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTGVNIPIITELVNDTNVQFLDQDDDDDPDTELYL
TQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRDRCRVAQLALLDGPFADLGDGGC
YGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLIFCLMQFDHNAGQSRASLSHSSHSSQSSSKKSSSVHS

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>2469_2469_7_ADK-KCNMA1_ADK_chr10_75984349_ENST00000286621_KCNMA1_chr10_78778857_ENST00000404857_length(amino acids)=642AA_BP=65
MAAAEEEPKPKKLKVEAPQALRENILFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELILINPGNHLKIQEGTLGFFIASDAK
EVKRAFFYCKACHDDITDPKRIKKCGCKRLEDEQPSTLSPKKKQRNGGMRNSPNTSPKLMRHDPLLIPGNDQIDNMDSNVKKYDSTGMFH
WCAPKEIEKVILVTGWMPYLGPRVLMTCLDIGVVCMPTDIQSTSPASIKKFKETRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLVMPLR
ASNFHYHELKHIVFVGSIEYLKREWETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSANQNNIDDTSLQDKECILASLNIKSMQF
DDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTGVNIPIITELVNDTNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDS
LMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRDRCRVAQLALLDGPFADLGDGGCYGDLFCKALKTYNMLCF
GIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLIFCLMQFDHNAGQSRASLSHSSHSSQSSSKKSSSVHSIPSTANRQNRPKSRESR

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>2469_2469_8_ADK-KCNMA1_ADK_chr10_75984349_ENST00000286621_KCNMA1_chr10_78778857_ENST00000406533_length(amino acids)=660AA_BP=65
MAAAEEEPKPKKLKVEAPQALRENILFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELSILINPGNHLKIQEGTLGFFIASDA
KEVKRAFFYCKACHDDITDPKRIKKCGCKRPKMSIYKRMRRACCFDCGRSERDCSCMSGRVRGNVDTLERAFPLSSVSVNDCSTSFRAFE
DEQPSTLSPKKKQRNGGMRNSPNTSPKLMRHDPLLIPGNDQIDNMDSNVKKYDSTGMFHWCAPKEIEKVILTRSEAAMTVLSGHVVVCIF
GDVSSALIGLRNLVMPLRASNFHYHELKHIVFVGSIEYLKREWETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSANQNNIDDTS
LQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTGVNIPIITELVNDTNVQFLDQDDDDDPDTELY
LTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRDRCRVAQLALLDGPFADLGDGG
CYGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLIFCLMQFDHNAGQSRASLSHSSHSSQSSSKKSSSVH

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>2469_2469_9_ADK-KCNMA1_ADK_chr10_75984349_ENST00000372734_KCNMA1_chr10_78778857_ENST00000286627_length(amino acids)=583AA_BP=48
MTSVRENILFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYCKACHDDIT
DPKRIKKCGCKRLEDEQPSTLSPKKKQRNGGMRNSPNTSPKLMRHDPLLIPGNDQIDNMDSNVKKYDSTGMFHWCAPKEIEKVILTRSEA
AMTVLSGHVVVCIFGDVSSALIGLRNLVMPLRASNFHYHELKHIVFVGSIEYLKREWETLHNFPKVSILPGTPLSRADLRAVNINLCDMC
VILSANQNNIDDTSLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTGVNIPIITELVNDTNVQF
LDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRDRCRVAQL
ALLDGPFADLGDGGCYGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLIFCLMQFDHNAGQSRASLSHSS

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>2469_2469_10_ADK-KCNMA1_ADK_chr10_75984349_ENST00000372734_KCNMA1_chr10_78778857_ENST00000286628_length(amino acids)=641AA_BP=48
MTSVRENILFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYCKACHDDIT
DPKRIKKCGCKRPKMSIYKRMRRACCFDCGRSERDCSCMSGRVRGNVDTLERAFPLSSVSVNDCSTSFRAFEDEQPSTLSPKKKQRNGGM
RNSPNTSPKLMRHDPLLIPGNDQIDNMDSNVKKYDSTGMFHWCAPKEIEKVILTRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLVMPLR
ASNFHYHELKHIVFVGSIEYLKREWETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSANQNNIDDTSLQDKECILASLNIKSMQF
DDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTGVNIPIITELVNDTNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDS
LMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRDRCRVAQLALLDGPFADLGDGGCYGDLFCKALKTYNMLCF
GIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLIFCLMQFDHNAGQSRASLSHSSHSSQSSSKKSSSVHSIPSTANRQNRPKSRESR

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>2469_2469_11_ADK-KCNMA1_ADK_chr10_75984349_ENST00000372734_KCNMA1_chr10_78778857_ENST00000354353_length(amino acids)=645AA_BP=48
MTSVRENILFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYCKACHDDIT
DPKRIKKCGCKRRWEEHCSLWRLESKGNVRRLNYCRGQQTFSVKVKVAARSRYSKDPFEFKKETPNSRLVTEPVEDEQPSTLSPKKKQRN
GGMRNSPNTSPKLMRHDPLLIPGNDQIDNMDSNVKKYDSTGMFHWCAPKEIEKVILTRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLVM
PLRASNFHYHELKHIVFVGSIEYLKREWETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSANQNNIDDTSLQDKECILASLNIKS
MQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTGVNIPIITELVNDTNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSV
LDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRDRCRVAQLALLDGPFADLGDGGCYGDLFCKALKTYNM
LCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLIFCLMQFDHNAGQSRASLSHSSHSSQSSSKKSSSVHSIPSTANRQNRPKSR

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>2469_2469_12_ADK-KCNMA1_ADK_chr10_75984349_ENST00000372734_KCNMA1_chr10_78778857_ENST00000372440_length(amino acids)=582AA_BP=48
MTSVRENILFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYCKACHDDIT
DPKRIKKCGCKRLEDEQPSTLSPKKKQRNGGMRNSPNTSPKLMRHDPLLIPGNDQIDNMDSNVKKYDSTGMFHWCAPKEIEKVILTRSEA
AMTVLSGHVVVCIFGDVSSALIGLRNLVMPLRASNFHYHELKHIVFVGSIEYLKREWETLHNFPKVSILPGTPLSRADLRAVNINLCDMC
VILSANQNNIDDTSLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTGVNIPIITELVNDTNVQF
LDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRDRCRVAQL
ALLDGPFADLGDGGCYGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLIFCLMQFDHNAGQSRASLSHSS

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>2469_2469_13_ADK-KCNMA1_ADK_chr10_75984349_ENST00000372734_KCNMA1_chr10_78778857_ENST00000372443_length(amino acids)=610AA_BP=48
MTSVRENILFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYCKACHDDIT
DPKRIKKCGCKRLEDEQPSTLSPKKKQRNGGMRNSPNTSPKLMRHDPLLIPGNDQIDNMDSNVKKYDSTGMFHWCAPKEIEKVILTRSEA
AMTVLSGHVVVCIFGDVSSALIGLRNLVMPLRASNFHYHELKHIVFVGSIEYLKREWETLHNFPKVSILPGTPLSRADLRAVNINLCDMC
VILSANQNNIDDTSLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTGVNIPIITELAKPGKLPL
VSVNQEKNSGTHILMITELVNDTNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALI
AEENALRGGYSTPQTLANRDRCRVAQLALLDGPFADLGDGGCYGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFEL

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>2469_2469_14_ADK-KCNMA1_ADK_chr10_75984349_ENST00000372734_KCNMA1_chr10_78778857_ENST00000404771_length(amino acids)=693AA_BP=48
MTSVRENILFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYCKACHDDIT
DPKRIKKCGCKRPKMSIYKRMRRACCFDCGRSERDCSCMSGRVRGNVDTLERAFPLSSVSVNDCSTSFRAFEDEQPSTLSPKKKQRNGGM
RNSPNTSPKLMRHDPLLIPGNDQIDNMDSNVKKYDSTGMFHWCAPKEIEKVILTRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLVMPLR
ASNFHYHELKHIVFVGSIEYLKREWETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSANQNNIDDTSLQDKECILASLNIKSMQF
DDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTGVNIPIITELVNDTNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDS
LMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRDRCRVAQLALLDGPFADLGDGGCYGDLFCKALKTYNMLCF
GIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLIFCLMQFDHNAGQSRASLSHSSHSSQSSSKKSSSVHSIPSTANRQNRPKSRESR

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>2469_2469_15_ADK-KCNMA1_ADK_chr10_75984349_ENST00000372734_KCNMA1_chr10_78778857_ENST00000404857_length(amino acids)=625AA_BP=48
MTSVRENILFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYCKACHDDIT
DPKRIKKCGCKRLEDEQPSTLSPKKKQRNGGMRNSPNTSPKLMRHDPLLIPGNDQIDNMDSNVKKYDSTGMFHWCAPKEIEKVILVTGWM
PYLGPRVLMTCLDIGVVCMPTDIQSTSPASIKKFKETRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLVMPLRASNFHYHELKHIVFVGS
IEYLKREWETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSANQNNIDDTSLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPP
GMDRSSPDNSPVHGMLRQPSITTGVNIPIITELVNDTNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRT
LVTGGATPELEALIAEENALRGGYSTPQTLANRDRCRVAQLALLDGPFADLGDGGCYGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCT

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>2469_2469_16_ADK-KCNMA1_ADK_chr10_75984349_ENST00000372734_KCNMA1_chr10_78778857_ENST00000406533_length(amino acids)=643AA_BP=48
MTSVRENILFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELSILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYCKACHDDI
TDPKRIKKCGCKRPKMSIYKRMRRACCFDCGRSERDCSCMSGRVRGNVDTLERAFPLSSVSVNDCSTSFRAFEDEQPSTLSPKKKQRNGG
MRNSPNTSPKLMRHDPLLIPGNDQIDNMDSNVKKYDSTGMFHWCAPKEIEKVILTRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLVMPL
RASNFHYHELKHIVFVGSIEYLKREWETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSANQNNIDDTSLQDKECILASLNIKSMQ
FDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTGVNIPIITELVNDTNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLD
SLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRDRCRVAQLALLDGPFADLGDGGCYGDLFCKALKTYNMLC
FGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLIFCLMQFDHNAGQSRASLSHSSHSSQSSSKKSSSVHSIPSTANRQNRPKSRES

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>2469_2469_17_ADK-KCNMA1_ADK_chr10_75984349_ENST00000539909_KCNMA1_chr10_78778857_ENST00000286627_length(amino acids)=600AA_BP=65
MAAAEEEPKPKKLKVEAPQALRENILFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELILINPGNHLKIQEGTLGFFIASDAK
EVKRAFFYCKACHDDITDPKRIKKCGCKRLEDEQPSTLSPKKKQRNGGMRNSPNTSPKLMRHDPLLIPGNDQIDNMDSNVKKYDSTGMFH
WCAPKEIEKVILTRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLVMPLRASNFHYHELKHIVFVGSIEYLKREWETLHNFPKVSILPGTP
LSRADLRAVNINLCDMCVILSANQNNIDDTSLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTG
VNIPIITELVNDTNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGY
STPQTLANRDRCRVAQLALLDGPFADLGDGGCYGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLIFCLM

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>2469_2469_18_ADK-KCNMA1_ADK_chr10_75984349_ENST00000539909_KCNMA1_chr10_78778857_ENST00000286628_length(amino acids)=658AA_BP=65
MAAAEEEPKPKKLKVEAPQALRENILFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELILINPGNHLKIQEGTLGFFIASDAK
EVKRAFFYCKACHDDITDPKRIKKCGCKRPKMSIYKRMRRACCFDCGRSERDCSCMSGRVRGNVDTLERAFPLSSVSVNDCSTSFRAFED
EQPSTLSPKKKQRNGGMRNSPNTSPKLMRHDPLLIPGNDQIDNMDSNVKKYDSTGMFHWCAPKEIEKVILTRSEAAMTVLSGHVVVCIFG
DVSSALIGLRNLVMPLRASNFHYHELKHIVFVGSIEYLKREWETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSANQNNIDDTSL
QDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTGVNIPIITELVNDTNVQFLDQDDDDDPDTELYL
TQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRDRCRVAQLALLDGPFADLGDGGC
YGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLIFCLMQFDHNAGQSRASLSHSSHSSQSSSKKSSSVHS

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>2469_2469_19_ADK-KCNMA1_ADK_chr10_75984349_ENST00000539909_KCNMA1_chr10_78778857_ENST00000354353_length(amino acids)=662AA_BP=65
MAAAEEEPKPKKLKVEAPQALRENILFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELILINPGNHLKIQEGTLGFFIASDAK
EVKRAFFYCKACHDDITDPKRIKKCGCKRRWEEHCSLWRLESKGNVRRLNYCRGQQTFSVKVKVAARSRYSKDPFEFKKETPNSRLVTEP
VEDEQPSTLSPKKKQRNGGMRNSPNTSPKLMRHDPLLIPGNDQIDNMDSNVKKYDSTGMFHWCAPKEIEKVILTRSEAAMTVLSGHVVVC
IFGDVSSALIGLRNLVMPLRASNFHYHELKHIVFVGSIEYLKREWETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSANQNNIDD
TSLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTGVNIPIITELVNDTNVQFLDQDDDDDPDTE
LYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRDRCRVAQLALLDGPFADLGD
GGCYGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLIFCLMQFDHNAGQSRASLSHSSHSSQSSSKKSSS

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>2469_2469_20_ADK-KCNMA1_ADK_chr10_75984349_ENST00000539909_KCNMA1_chr10_78778857_ENST00000372440_length(amino acids)=599AA_BP=65
MAAAEEEPKPKKLKVEAPQALRENILFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELILINPGNHLKIQEGTLGFFIASDAK
EVKRAFFYCKACHDDITDPKRIKKCGCKRLEDEQPSTLSPKKKQRNGGMRNSPNTSPKLMRHDPLLIPGNDQIDNMDSNVKKYDSTGMFH
WCAPKEIEKVILTRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLVMPLRASNFHYHELKHIVFVGSIEYLKREWETLHNFPKVSILPGTP
LSRADLRAVNINLCDMCVILSANQNNIDDTSLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTG
VNIPIITELVNDTNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGY
STPQTLANRDRCRVAQLALLDGPFADLGDGGCYGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLIFCLM

--------------------------------------------------------------

>2469_2469_21_ADK-KCNMA1_ADK_chr10_75984349_ENST00000539909_KCNMA1_chr10_78778857_ENST00000372443_length(amino acids)=627AA_BP=65
MAAAEEEPKPKKLKVEAPQALRENILFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELILINPGNHLKIQEGTLGFFIASDAK
EVKRAFFYCKACHDDITDPKRIKKCGCKRLEDEQPSTLSPKKKQRNGGMRNSPNTSPKLMRHDPLLIPGNDQIDNMDSNVKKYDSTGMFH
WCAPKEIEKVILTRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLVMPLRASNFHYHELKHIVFVGSIEYLKREWETLHNFPKVSILPGTP
LSRADLRAVNINLCDMCVILSANQNNIDDTSLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTG
VNIPIITELAKPGKLPLVSVNQEKNSGTHILMITELVNDTNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTL
IRTLVTGGATPELEALIAEENALRGGYSTPQTLANRDRCRVAQLALLDGPFADLGDGGCYGDLFCKALKTYNMLCFGIYRLRDAHLSTPS

--------------------------------------------------------------

>2469_2469_22_ADK-KCNMA1_ADK_chr10_75984349_ENST00000539909_KCNMA1_chr10_78778857_ENST00000404771_length(amino acids)=710AA_BP=65
MAAAEEEPKPKKLKVEAPQALRENILFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELILINPGNHLKIQEGTLGFFIASDAK
EVKRAFFYCKACHDDITDPKRIKKCGCKRPKMSIYKRMRRACCFDCGRSERDCSCMSGRVRGNVDTLERAFPLSSVSVNDCSTSFRAFED
EQPSTLSPKKKQRNGGMRNSPNTSPKLMRHDPLLIPGNDQIDNMDSNVKKYDSTGMFHWCAPKEIEKVILTRSEAAMTVLSGHVVVCIFG
DVSSALIGLRNLVMPLRASNFHYHELKHIVFVGSIEYLKREWETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSANQNNIDDTSL
QDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTGVNIPIITELVNDTNVQFLDQDDDDDPDTELYL
TQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRDRCRVAQLALLDGPFADLGDGGC
YGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLIFCLMQFDHNAGQSRASLSHSSHSSQSSSKKSSSVHS

--------------------------------------------------------------

>2469_2469_23_ADK-KCNMA1_ADK_chr10_75984349_ENST00000539909_KCNMA1_chr10_78778857_ENST00000404857_length(amino acids)=642AA_BP=65
MAAAEEEPKPKKLKVEAPQALRENILFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELILINPGNHLKIQEGTLGFFIASDAK
EVKRAFFYCKACHDDITDPKRIKKCGCKRLEDEQPSTLSPKKKQRNGGMRNSPNTSPKLMRHDPLLIPGNDQIDNMDSNVKKYDSTGMFH
WCAPKEIEKVILVTGWMPYLGPRVLMTCLDIGVVCMPTDIQSTSPASIKKFKETRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLVMPLR
ASNFHYHELKHIVFVGSIEYLKREWETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSANQNNIDDTSLQDKECILASLNIKSMQF
DDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTGVNIPIITELVNDTNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDS
LMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRDRCRVAQLALLDGPFADLGDGGCYGDLFCKALKTYNMLCF
GIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLIFCLMQFDHNAGQSRASLSHSSHSSQSSSKKSSSVHSIPSTANRQNRPKSRESR

--------------------------------------------------------------

>2469_2469_24_ADK-KCNMA1_ADK_chr10_75984349_ENST00000539909_KCNMA1_chr10_78778857_ENST00000406533_length(amino acids)=660AA_BP=65
MAAAEEEPKPKKLKVEAPQALRENILFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELSILINPGNHLKIQEGTLGFFIASDA
KEVKRAFFYCKACHDDITDPKRIKKCGCKRPKMSIYKRMRRACCFDCGRSERDCSCMSGRVRGNVDTLERAFPLSSVSVNDCSTSFRAFE
DEQPSTLSPKKKQRNGGMRNSPNTSPKLMRHDPLLIPGNDQIDNMDSNVKKYDSTGMFHWCAPKEIEKVILTRSEAAMTVLSGHVVVCIF
GDVSSALIGLRNLVMPLRASNFHYHELKHIVFVGSIEYLKREWETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSANQNNIDDTS
LQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTGVNIPIITELVNDTNVQFLDQDDDDDPDTELY
LTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRDRCRVAQLALLDGPFADLGDGG
CYGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLIFCLMQFDHNAGQSRASLSHSSHSSQSSSKKSSSVH

--------------------------------------------------------------

>2469_2469_25_ADK-KCNMA1_ADK_chr10_76074503_ENST00000286621_KCNMA1_chr10_79011014_ENST00000286627_length(amino acids)=1089AA_BP=90
MAAAEEEPKPKKLKVEAPQALRENILFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELFDELVKKFKVEYHAGGSTQNSIKVA
QVVLVFALSIGALVIYFIDSSNPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWL
GLRFLRALRLIQFSEILQFLNILKTSNSIKLVNLLSIFISTWLTAAGFIHLVENSGDPWENFQNNQALTYWECVYLLMVTMSTVGYGDVY
AKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPN
LELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPS
WNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSAFVGLSFPTVCELCFVKLKLL
MIAIEYKSANRESRILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYCKACHDDITDPKRIKKCGCKRLEDEQPSTLSPKKKQRNGGMRN
SPNTSPKLMRHDPLLIPGNDQIDNMDSNVKKYDSTGMFHWCAPKEIEKVILTRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLVMPLRAS
NFHYHELKHIVFVGSIEYLKREWETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSANQNNIDDTSLQDKECILASLNIKSMQFDD
SIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTGVNIPIITELVNDTNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLM
SATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRDRCRVAQLALLDGPFADLGDGGCYGDLFCKALKTYNMLCFGI
YRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLIFCLMQFDHNAGQSRASLSHSSHSSQSSSKKSSSVHSIPSTANRQNRPKSRESRDK

--------------------------------------------------------------

>2469_2469_26_ADK-KCNMA1_ADK_chr10_76074503_ENST00000286621_KCNMA1_chr10_79011014_ENST00000286628_length(amino acids)=1147AA_BP=90
MAAAEEEPKPKKLKVEAPQALRENILFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELFDELVKKFKVEYHAGGSTQNSIKVA
QVVLVFALSIGALVIYFIDSSNPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWL
GLRFLRALRLIQFSEILQFLNILKTSNSIKLVNLLSIFISTWLTAAGFIHLVENSGDPWENFQNNQALTYWECVYLLMVTMSTVGYGDVY
AKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPN
LELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPS
WNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSAFVGLSFPTVCELCFVKLKLL
MIAIEYKSANRESRILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYCKACHDDITDPKRIKKCGCKRPKMSIYKRMRRACCFDCGRSER
DCSCMSGRVRGNVDTLERAFPLSSVSVNDCSTSFRAFEDEQPSTLSPKKKQRNGGMRNSPNTSPKLMRHDPLLIPGNDQIDNMDSNVKKY
DSTGMFHWCAPKEIEKVILTRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLVMPLRASNFHYHELKHIVFVGSIEYLKREWETLHNFPKV
SILPGTPLSRADLRAVNINLCDMCVILSANQNNIDDTSLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLR
QPSITTGVNIPIITELVNDTNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEE
NALRGGYSTPQTLANRDRCRVAQLALLDGPFADLGDGGCYGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPT

--------------------------------------------------------------

>2469_2469_27_ADK-KCNMA1_ADK_chr10_76074503_ENST00000286621_KCNMA1_chr10_79011014_ENST00000354353_length(amino acids)=1151AA_BP=90
MAAAEEEPKPKKLKVEAPQALRENILFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELFDELVKKFKVEYHAGGSTQNSIKVA
QVVLVFALSIGALVIYFIDSSNPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWL
GLRFLRALRLIQFSEILQFLNILKTSNSIKLVNLLSIFISTWLTAAGFIHLVENSGDPWENFQNNQALTYWECVYLLMVTMSTVGYGDVY
AKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPN
LELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPS
WNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSAFVGLSFPTVCELCFVKLKLL
MIAIEYKSANRESRILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYCKACHDDITDPKRIKKCGCKRRWEEHCSLWRLESKGNVRRLNY
CRGQQTFSVKVKVAARSRYSKDPFEFKKETPNSRLVTEPVEDEQPSTLSPKKKQRNGGMRNSPNTSPKLMRHDPLLIPGNDQIDNMDSNV
KKYDSTGMFHWCAPKEIEKVILTRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLVMPLRASNFHYHELKHIVFVGSIEYLKREWETLHNF
PKVSILPGTPLSRADLRAVNINLCDMCVILSANQNNIDDTSLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHG
MLRQPSITTGVNIPIITELVNDTNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALI
AEENALRGGYSTPQTLANRDRCRVAQLALLDGPFADLGDGGCYGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFEL

--------------------------------------------------------------

>2469_2469_28_ADK-KCNMA1_ADK_chr10_76074503_ENST00000286621_KCNMA1_chr10_79011014_ENST00000372440_length(amino acids)=1088AA_BP=90
MAAAEEEPKPKKLKVEAPQALRENILFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELFDELVKKFKVEYHAGGSTQNSIKVA
QVVLVFALSIGALVIYFIDSSNPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWL
GLRFLRALRLIQFSEILQFLNILKTSNSIKLVNLLSIFISTWLTAAGFIHLVENSGDPWENFQNNQALTYWECVYLLMVTMSTVGYGDVY
AKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPN
LELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPS
WNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSAFVGLSFPTVCELCFVKLKLL
MIAIEYKSANRESRILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYCKACHDDITDPKRIKKCGCKRLEDEQPSTLSPKKKQRNGGMRN
SPNTSPKLMRHDPLLIPGNDQIDNMDSNVKKYDSTGMFHWCAPKEIEKVILTRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLVMPLRAS
NFHYHELKHIVFVGSIEYLKREWETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSANQNNIDDTSLQDKECILASLNIKSMQFDD
SIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTGVNIPIITELVNDTNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLM
SATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRDRCRVAQLALLDGPFADLGDGGCYGDLFCKALKTYNMLCFGI
YRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLIFCLMQFDHNAGQSRASLSHSSHSSQSSSKKSSSVHSIPSTANRQNRPKSRESRDK

--------------------------------------------------------------

>2469_2469_29_ADK-KCNMA1_ADK_chr10_76074503_ENST00000286621_KCNMA1_chr10_79011014_ENST00000372443_length(amino acids)=1116AA_BP=90
MAAAEEEPKPKKLKVEAPQALRENILFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELFDELVKKFKVEYHAGGSTQNSIKVA
QVVLVFALSIGALVIYFIDSSNPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWL
GLRFLRALRLIQFSEILQFLNILKTSNSIKLVNLLSIFISTWLTAAGFIHLVENSGDPWENFQNNQALTYWECVYLLMVTMSTVGYGDVY
AKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPN
LELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPS
WNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSAFVGLSFPTVCELCFVKLKLL
MIAIEYKSANRESRILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYCKACHDDITDPKRIKKCGCKRLEDEQPSTLSPKKKQRNGGMRN
SPNTSPKLMRHDPLLIPGNDQIDNMDSNVKKYDSTGMFHWCAPKEIEKVILTRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLVMPLRAS
NFHYHELKHIVFVGSIEYLKREWETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSANQNNIDDTSLQDKECILASLNIKSMQFDD
SIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTGVNIPIITELAKPGKLPLVSVNQEKNSGTHILMITELVNDTNVQFLDQDDDD
DPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRDRCRVAQLALLDGPF
ADLGDGGCYGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLIFCLMQFDHNAGQSRASLSHSSHSSQSSS

--------------------------------------------------------------

>2469_2469_30_ADK-KCNMA1_ADK_chr10_76074503_ENST00000286621_KCNMA1_chr10_79011014_ENST00000404771_length(amino acids)=1199AA_BP=90
MAAAEEEPKPKKLKVEAPQALRENILFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELFDELVKKFKVEYHAGGSTQNSIKVA
QVVLVFALSIGALVIYFIDSSNPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWL
GLRFLRALRLIQFSEILQFLNILKTSNSIKLVNLLSIFISTWLTAAGFIHLVENSGDPWENFQNNQALTYWECVYLLMVTMSTVGYGDVY
AKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPN
LELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPS
WNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSAFVGLSFPTVCELCFVKLKLL
MIAIEYKSANRESRILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYCKACHDDITDPKRIKKCGCKRPKMSIYKRMRRACCFDCGRSER
DCSCMSGRVRGNVDTLERAFPLSSVSVNDCSTSFRAFEDEQPSTLSPKKKQRNGGMRNSPNTSPKLMRHDPLLIPGNDQIDNMDSNVKKY
DSTGMFHWCAPKEIEKVILTRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLVMPLRASNFHYHELKHIVFVGSIEYLKREWETLHNFPKV
SILPGTPLSRADLRAVNINLCDMCVILSANQNNIDDTSLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLR
QPSITTGVNIPIITELVNDTNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEE
NALRGGYSTPQTLANRDRCRVAQLALLDGPFADLGDGGCYGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPT
DLIFCLMQFDHNAGQSRASLSHSSHSSQSSSKKSSSVHSIPSTANRQNRPKSRESRDKQNATRMNRMGQEKKWFTDEPDNAYPRNIQIKP

--------------------------------------------------------------

>2469_2469_31_ADK-KCNMA1_ADK_chr10_76074503_ENST00000286621_KCNMA1_chr10_79011014_ENST00000404857_length(amino acids)=1131AA_BP=90
MAAAEEEPKPKKLKVEAPQALRENILFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELFDELVKKFKVEYHAGGSTQNSIKVA
QVVLVFALSIGALVIYFIDSSNPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWL
GLRFLRALRLIQFSEILQFLNILKTSNSIKLVNLLSIFISTWLTAAGFIHLVENSGDPWENFQNNQALTYWECVYLLMVTMSTVGYGDVY
AKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPN
LELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPS
WNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSAFVGLSFPTVCELCFVKLKLL
MIAIEYKSANRESRILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYCKACHDDITDPKRIKKCGCKRLEDEQPSTLSPKKKQRNGGMRN
SPNTSPKLMRHDPLLIPGNDQIDNMDSNVKKYDSTGMFHWCAPKEIEKVILVTGWMPYLGPRVLMTCLDIGVVCMPTDIQSTSPASIKKF
KETRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLVMPLRASNFHYHELKHIVFVGSIEYLKREWETLHNFPKVSILPGTPLSRADLRAVN
INLCDMCVILSANQNNIDDTSLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTGVNIPIITELV
NDTNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRD
RCRVAQLALLDGPFADLGDGGCYGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLIFCLMQFDHNAGQSR

--------------------------------------------------------------

>2469_2469_32_ADK-KCNMA1_ADK_chr10_76074503_ENST00000286621_KCNMA1_chr10_79011014_ENST00000406533_length(amino acids)=1152AA_BP=90
MAAAEEEPKPKKLKVEAPQALRENILFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELFDELVKKFKVEYHAGGSTQNSIKVA
QVVLVFALSIGALVIYFIDSSNPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWL
GLRFLRALRLIQFSEILQFLNILKTSNSIKLVNLLSIFISTWLTAAGFIHLVENSGDPWENFQNNQALTYWECVYLLMVTMSTVGYGDVY
AKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPN
LELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPS
WNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSAFVGLSFPTVCELCFVKLKLL
MIAIEYKSANRESRGRLSILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYCKACHDDITDPKRIKKCGCKRPKMSIYKRMRRACCFDCG
RSERDCSCMSGRVRGNVDTLERAFPLSSVSVNDCSTSFRAFEDEQPSTLSPKKKQRNGGMRNSPNTSPKLMRHDPLLIPGNDQIDNMDSN
VKKYDSTGMFHWCAPKEIEKVILTRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLVMPLRASNFHYHELKHIVFVGSIEYLKREWETLHN
FPKVSILPGTPLSRADLRAVNINLCDMCVILSANQNNIDDTSLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVH
GMLRQPSITTGVNIPIITELVNDTNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEAL
IAEENALRGGYSTPQTLANRDRCRVAQLALLDGPFADLGDGGCYGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFE

--------------------------------------------------------------

>2469_2469_33_ADK-KCNMA1_ADK_chr10_76074503_ENST00000372734_KCNMA1_chr10_79011014_ENST00000286627_length(amino acids)=1072AA_BP=73
MTSVRENILFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELFDELVKKFKVEYHAGGSTQNSIKVAQVVLVFALSIGALVIYF
IDSSNPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEIL
QFLNILKTSNSIKLVNLLSIFISTWLTAAGFIHLVENSGDPWENFQNNQALTYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGG
LAMFASYVPEIIELIGNRKKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPNLELEALFKRHFTQVEFY
QGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKL
GFIAQSCLAQGLSTMLANLFSMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSAFVGLSFPTVCELCFVKLKLLMIAIEYKSANRESRILI
NPGNHLKIQEGTLGFFIASDAKEVKRAFFYCKACHDDITDPKRIKKCGCKRLEDEQPSTLSPKKKQRNGGMRNSPNTSPKLMRHDPLLIP
GNDQIDNMDSNVKKYDSTGMFHWCAPKEIEKVILTRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLVMPLRASNFHYHELKHIVFVGSIE
YLKREWETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSANQNNIDDTSLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGM
DRSSPDNSPVHGMLRQPSITTGVNIPIITELVNDTNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLV
TGGATPELEALIAEENALRGGYSTPQTLANRDRCRVAQLALLDGPFADLGDGGCYGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKR

--------------------------------------------------------------

>2469_2469_34_ADK-KCNMA1_ADK_chr10_76074503_ENST00000372734_KCNMA1_chr10_79011014_ENST00000286628_length(amino acids)=1130AA_BP=73
MTSVRENILFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELFDELVKKFKVEYHAGGSTQNSIKVAQVVLVFALSIGALVIYF
IDSSNPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEIL
QFLNILKTSNSIKLVNLLSIFISTWLTAAGFIHLVENSGDPWENFQNNQALTYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGG
LAMFASYVPEIIELIGNRKKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPNLELEALFKRHFTQVEFY
QGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKL
GFIAQSCLAQGLSTMLANLFSMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSAFVGLSFPTVCELCFVKLKLLMIAIEYKSANRESRILI
NPGNHLKIQEGTLGFFIASDAKEVKRAFFYCKACHDDITDPKRIKKCGCKRPKMSIYKRMRRACCFDCGRSERDCSCMSGRVRGNVDTLE
RAFPLSSVSVNDCSTSFRAFEDEQPSTLSPKKKQRNGGMRNSPNTSPKLMRHDPLLIPGNDQIDNMDSNVKKYDSTGMFHWCAPKEIEKV
ILTRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLVMPLRASNFHYHELKHIVFVGSIEYLKREWETLHNFPKVSILPGTPLSRADLRAVN
INLCDMCVILSANQNNIDDTSLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTGVNIPIITELV
NDTNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRD
RCRVAQLALLDGPFADLGDGGCYGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLIFCLMQFDHNAGQSR

--------------------------------------------------------------

>2469_2469_35_ADK-KCNMA1_ADK_chr10_76074503_ENST00000372734_KCNMA1_chr10_79011014_ENST00000354353_length(amino acids)=1134AA_BP=73
MTSVRENILFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELFDELVKKFKVEYHAGGSTQNSIKVAQVVLVFALSIGALVIYF
IDSSNPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEIL
QFLNILKTSNSIKLVNLLSIFISTWLTAAGFIHLVENSGDPWENFQNNQALTYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGG
LAMFASYVPEIIELIGNRKKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPNLELEALFKRHFTQVEFY
QGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKL
GFIAQSCLAQGLSTMLANLFSMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSAFVGLSFPTVCELCFVKLKLLMIAIEYKSANRESRILI
NPGNHLKIQEGTLGFFIASDAKEVKRAFFYCKACHDDITDPKRIKKCGCKRRWEEHCSLWRLESKGNVRRLNYCRGQQTFSVKVKVAARS
RYSKDPFEFKKETPNSRLVTEPVEDEQPSTLSPKKKQRNGGMRNSPNTSPKLMRHDPLLIPGNDQIDNMDSNVKKYDSTGMFHWCAPKEI
EKVILTRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLVMPLRASNFHYHELKHIVFVGSIEYLKREWETLHNFPKVSILPGTPLSRADLR
AVNINLCDMCVILSANQNNIDDTSLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTGVNIPIIT
ELVNDTNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLA
NRDRCRVAQLALLDGPFADLGDGGCYGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLIFCLMQFDHNAG

--------------------------------------------------------------

>2469_2469_36_ADK-KCNMA1_ADK_chr10_76074503_ENST00000372734_KCNMA1_chr10_79011014_ENST00000372440_length(amino acids)=1071AA_BP=73
MTSVRENILFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELFDELVKKFKVEYHAGGSTQNSIKVAQVVLVFALSIGALVIYF
IDSSNPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEIL
QFLNILKTSNSIKLVNLLSIFISTWLTAAGFIHLVENSGDPWENFQNNQALTYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGG
LAMFASYVPEIIELIGNRKKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPNLELEALFKRHFTQVEFY
QGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKL
GFIAQSCLAQGLSTMLANLFSMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSAFVGLSFPTVCELCFVKLKLLMIAIEYKSANRESRILI
NPGNHLKIQEGTLGFFIASDAKEVKRAFFYCKACHDDITDPKRIKKCGCKRLEDEQPSTLSPKKKQRNGGMRNSPNTSPKLMRHDPLLIP
GNDQIDNMDSNVKKYDSTGMFHWCAPKEIEKVILTRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLVMPLRASNFHYHELKHIVFVGSIE
YLKREWETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSANQNNIDDTSLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGM
DRSSPDNSPVHGMLRQPSITTGVNIPIITELVNDTNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLV
TGGATPELEALIAEENALRGGYSTPQTLANRDRCRVAQLALLDGPFADLGDGGCYGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKR

--------------------------------------------------------------

>2469_2469_37_ADK-KCNMA1_ADK_chr10_76074503_ENST00000372734_KCNMA1_chr10_79011014_ENST00000372443_length(amino acids)=1099AA_BP=73
MTSVRENILFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELFDELVKKFKVEYHAGGSTQNSIKVAQVVLVFALSIGALVIYF
IDSSNPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEIL
QFLNILKTSNSIKLVNLLSIFISTWLTAAGFIHLVENSGDPWENFQNNQALTYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGG
LAMFASYVPEIIELIGNRKKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPNLELEALFKRHFTQVEFY
QGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKL
GFIAQSCLAQGLSTMLANLFSMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSAFVGLSFPTVCELCFVKLKLLMIAIEYKSANRESRILI
NPGNHLKIQEGTLGFFIASDAKEVKRAFFYCKACHDDITDPKRIKKCGCKRLEDEQPSTLSPKKKQRNGGMRNSPNTSPKLMRHDPLLIP
GNDQIDNMDSNVKKYDSTGMFHWCAPKEIEKVILTRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLVMPLRASNFHYHELKHIVFVGSIE
YLKREWETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSANQNNIDDTSLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGM
DRSSPDNSPVHGMLRQPSITTGVNIPIITELAKPGKLPLVSVNQEKNSGTHILMITELVNDTNVQFLDQDDDDDPDTELYLTQPFACGTA
FAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRDRCRVAQLALLDGPFADLGDGGCYGDLFCKAL
KTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLIFCLMQFDHNAGQSRASLSHSSHSSQSSSKKSSSVHSIPSTANRQN

--------------------------------------------------------------

>2469_2469_38_ADK-KCNMA1_ADK_chr10_76074503_ENST00000372734_KCNMA1_chr10_79011014_ENST00000404771_length(amino acids)=1182AA_BP=73
MTSVRENILFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELFDELVKKFKVEYHAGGSTQNSIKVAQVVLVFALSIGALVIYF
IDSSNPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEIL
QFLNILKTSNSIKLVNLLSIFISTWLTAAGFIHLVENSGDPWENFQNNQALTYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGG
LAMFASYVPEIIELIGNRKKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPNLELEALFKRHFTQVEFY
QGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKL
GFIAQSCLAQGLSTMLANLFSMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSAFVGLSFPTVCELCFVKLKLLMIAIEYKSANRESRILI
NPGNHLKIQEGTLGFFIASDAKEVKRAFFYCKACHDDITDPKRIKKCGCKRPKMSIYKRMRRACCFDCGRSERDCSCMSGRVRGNVDTLE
RAFPLSSVSVNDCSTSFRAFEDEQPSTLSPKKKQRNGGMRNSPNTSPKLMRHDPLLIPGNDQIDNMDSNVKKYDSTGMFHWCAPKEIEKV
ILTRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLVMPLRASNFHYHELKHIVFVGSIEYLKREWETLHNFPKVSILPGTPLSRADLRAVN
INLCDMCVILSANQNNIDDTSLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTGVNIPIITELV
NDTNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRD
RCRVAQLALLDGPFADLGDGGCYGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLIFCLMQFDHNAGQSR
ASLSHSSHSSQSSSKKSSSVHSIPSTANRQNRPKSRESRDKQNATRMNRMGQEKKWFTDEPDNAYPRNIQIKPMSTHMANQINQYKSTSS

--------------------------------------------------------------

>2469_2469_39_ADK-KCNMA1_ADK_chr10_76074503_ENST00000372734_KCNMA1_chr10_79011014_ENST00000404857_length(amino acids)=1114AA_BP=73
MTSVRENILFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELFDELVKKFKVEYHAGGSTQNSIKVAQVVLVFALSIGALVIYF
IDSSNPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEIL
QFLNILKTSNSIKLVNLLSIFISTWLTAAGFIHLVENSGDPWENFQNNQALTYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGG
LAMFASYVPEIIELIGNRKKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPNLELEALFKRHFTQVEFY
QGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKL
GFIAQSCLAQGLSTMLANLFSMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSAFVGLSFPTVCELCFVKLKLLMIAIEYKSANRESRILI
NPGNHLKIQEGTLGFFIASDAKEVKRAFFYCKACHDDITDPKRIKKCGCKRLEDEQPSTLSPKKKQRNGGMRNSPNTSPKLMRHDPLLIP
GNDQIDNMDSNVKKYDSTGMFHWCAPKEIEKVILVTGWMPYLGPRVLMTCLDIGVVCMPTDIQSTSPASIKKFKETRSEAAMTVLSGHVV
VCIFGDVSSALIGLRNLVMPLRASNFHYHELKHIVFVGSIEYLKREWETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSANQNNI
DDTSLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTGVNIPIITELVNDTNVQFLDQDDDDDPD
TELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRDRCRVAQLALLDGPFADL
GDGGCYGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLIFCLMQFDHNAGQSRASLSHSSHSSQSSSKKS

--------------------------------------------------------------

>2469_2469_40_ADK-KCNMA1_ADK_chr10_76074503_ENST00000372734_KCNMA1_chr10_79011014_ENST00000406533_length(amino acids)=1135AA_BP=73
MTSVRENILFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELFDELVKKFKVEYHAGGSTQNSIKVAQVVLVFALSIGALVIYF
IDSSNPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEIL
QFLNILKTSNSIKLVNLLSIFISTWLTAAGFIHLVENSGDPWENFQNNQALTYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGG
LAMFASYVPEIIELIGNRKKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPNLELEALFKRHFTQVEFY
QGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKL
GFIAQSCLAQGLSTMLANLFSMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSAFVGLSFPTVCELCFVKLKLLMIAIEYKSANRESRGRL
SILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYCKACHDDITDPKRIKKCGCKRPKMSIYKRMRRACCFDCGRSERDCSCMSGRVRGNV
DTLERAFPLSSVSVNDCSTSFRAFEDEQPSTLSPKKKQRNGGMRNSPNTSPKLMRHDPLLIPGNDQIDNMDSNVKKYDSTGMFHWCAPKE
IEKVILTRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLVMPLRASNFHYHELKHIVFVGSIEYLKREWETLHNFPKVSILPGTPLSRADL
RAVNINLCDMCVILSANQNNIDDTSLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTGVNIPII
TELVNDTNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTL
ANRDRCRVAQLALLDGPFADLGDGGCYGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLIFCLMQFDHNA

--------------------------------------------------------------

>2469_2469_41_ADK-KCNMA1_ADK_chr10_76074503_ENST00000539909_KCNMA1_chr10_79011014_ENST00000286627_length(amino acids)=1089AA_BP=90
MAAAEEEPKPKKLKVEAPQALRENILFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELFDELVKKFKVEYHAGGSTQNSIKVA
QVVLVFALSIGALVIYFIDSSNPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWL
GLRFLRALRLIQFSEILQFLNILKTSNSIKLVNLLSIFISTWLTAAGFIHLVENSGDPWENFQNNQALTYWECVYLLMVTMSTVGYGDVY
AKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPN
LELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPS
WNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSAFVGLSFPTVCELCFVKLKLL
MIAIEYKSANRESRILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYCKACHDDITDPKRIKKCGCKRLEDEQPSTLSPKKKQRNGGMRN
SPNTSPKLMRHDPLLIPGNDQIDNMDSNVKKYDSTGMFHWCAPKEIEKVILTRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLVMPLRAS
NFHYHELKHIVFVGSIEYLKREWETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSANQNNIDDTSLQDKECILASLNIKSMQFDD
SIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTGVNIPIITELVNDTNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLM
SATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRDRCRVAQLALLDGPFADLGDGGCYGDLFCKALKTYNMLCFGI
YRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLIFCLMQFDHNAGQSRASLSHSSHSSQSSSKKSSSVHSIPSTANRQNRPKSRESRDK

--------------------------------------------------------------

>2469_2469_42_ADK-KCNMA1_ADK_chr10_76074503_ENST00000539909_KCNMA1_chr10_79011014_ENST00000286628_length(amino acids)=1147AA_BP=90
MAAAEEEPKPKKLKVEAPQALRENILFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELFDELVKKFKVEYHAGGSTQNSIKVA
QVVLVFALSIGALVIYFIDSSNPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWL
GLRFLRALRLIQFSEILQFLNILKTSNSIKLVNLLSIFISTWLTAAGFIHLVENSGDPWENFQNNQALTYWECVYLLMVTMSTVGYGDVY
AKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPN
LELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPS
WNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSAFVGLSFPTVCELCFVKLKLL
MIAIEYKSANRESRILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYCKACHDDITDPKRIKKCGCKRPKMSIYKRMRRACCFDCGRSER
DCSCMSGRVRGNVDTLERAFPLSSVSVNDCSTSFRAFEDEQPSTLSPKKKQRNGGMRNSPNTSPKLMRHDPLLIPGNDQIDNMDSNVKKY
DSTGMFHWCAPKEIEKVILTRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLVMPLRASNFHYHELKHIVFVGSIEYLKREWETLHNFPKV
SILPGTPLSRADLRAVNINLCDMCVILSANQNNIDDTSLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLR
QPSITTGVNIPIITELVNDTNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEE
NALRGGYSTPQTLANRDRCRVAQLALLDGPFADLGDGGCYGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPT

--------------------------------------------------------------

>2469_2469_43_ADK-KCNMA1_ADK_chr10_76074503_ENST00000539909_KCNMA1_chr10_79011014_ENST00000354353_length(amino acids)=1151AA_BP=90
MAAAEEEPKPKKLKVEAPQALRENILFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELFDELVKKFKVEYHAGGSTQNSIKVA
QVVLVFALSIGALVIYFIDSSNPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWL
GLRFLRALRLIQFSEILQFLNILKTSNSIKLVNLLSIFISTWLTAAGFIHLVENSGDPWENFQNNQALTYWECVYLLMVTMSTVGYGDVY
AKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPN
LELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPS
WNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSAFVGLSFPTVCELCFVKLKLL
MIAIEYKSANRESRILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYCKACHDDITDPKRIKKCGCKRRWEEHCSLWRLESKGNVRRLNY
CRGQQTFSVKVKVAARSRYSKDPFEFKKETPNSRLVTEPVEDEQPSTLSPKKKQRNGGMRNSPNTSPKLMRHDPLLIPGNDQIDNMDSNV
KKYDSTGMFHWCAPKEIEKVILTRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLVMPLRASNFHYHELKHIVFVGSIEYLKREWETLHNF
PKVSILPGTPLSRADLRAVNINLCDMCVILSANQNNIDDTSLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHG
MLRQPSITTGVNIPIITELVNDTNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALI
AEENALRGGYSTPQTLANRDRCRVAQLALLDGPFADLGDGGCYGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFEL

--------------------------------------------------------------

>2469_2469_44_ADK-KCNMA1_ADK_chr10_76074503_ENST00000539909_KCNMA1_chr10_79011014_ENST00000372440_length(amino acids)=1088AA_BP=90
MAAAEEEPKPKKLKVEAPQALRENILFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELFDELVKKFKVEYHAGGSTQNSIKVA
QVVLVFALSIGALVIYFIDSSNPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWL
GLRFLRALRLIQFSEILQFLNILKTSNSIKLVNLLSIFISTWLTAAGFIHLVENSGDPWENFQNNQALTYWECVYLLMVTMSTVGYGDVY
AKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPN
LELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPS
WNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSAFVGLSFPTVCELCFVKLKLL
MIAIEYKSANRESRILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYCKACHDDITDPKRIKKCGCKRLEDEQPSTLSPKKKQRNGGMRN
SPNTSPKLMRHDPLLIPGNDQIDNMDSNVKKYDSTGMFHWCAPKEIEKVILTRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLVMPLRAS
NFHYHELKHIVFVGSIEYLKREWETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSANQNNIDDTSLQDKECILASLNIKSMQFDD
SIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTGVNIPIITELVNDTNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLM
SATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRDRCRVAQLALLDGPFADLGDGGCYGDLFCKALKTYNMLCFGI
YRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLIFCLMQFDHNAGQSRASLSHSSHSSQSSSKKSSSVHSIPSTANRQNRPKSRESRDK

--------------------------------------------------------------

>2469_2469_45_ADK-KCNMA1_ADK_chr10_76074503_ENST00000539909_KCNMA1_chr10_79011014_ENST00000372443_length(amino acids)=1116AA_BP=90
MAAAEEEPKPKKLKVEAPQALRENILFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELFDELVKKFKVEYHAGGSTQNSIKVA
QVVLVFALSIGALVIYFIDSSNPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWL
GLRFLRALRLIQFSEILQFLNILKTSNSIKLVNLLSIFISTWLTAAGFIHLVENSGDPWENFQNNQALTYWECVYLLMVTMSTVGYGDVY
AKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPN
LELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPS
WNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSAFVGLSFPTVCELCFVKLKLL
MIAIEYKSANRESRILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYCKACHDDITDPKRIKKCGCKRLEDEQPSTLSPKKKQRNGGMRN
SPNTSPKLMRHDPLLIPGNDQIDNMDSNVKKYDSTGMFHWCAPKEIEKVILTRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLVMPLRAS
NFHYHELKHIVFVGSIEYLKREWETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSANQNNIDDTSLQDKECILASLNIKSMQFDD
SIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTGVNIPIITELAKPGKLPLVSVNQEKNSGTHILMITELVNDTNVQFLDQDDDD
DPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRDRCRVAQLALLDGPF
ADLGDGGCYGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLIFCLMQFDHNAGQSRASLSHSSHSSQSSS

--------------------------------------------------------------

>2469_2469_46_ADK-KCNMA1_ADK_chr10_76074503_ENST00000539909_KCNMA1_chr10_79011014_ENST00000404771_length(amino acids)=1199AA_BP=90
MAAAEEEPKPKKLKVEAPQALRENILFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELFDELVKKFKVEYHAGGSTQNSIKVA
QVVLVFALSIGALVIYFIDSSNPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWL
GLRFLRALRLIQFSEILQFLNILKTSNSIKLVNLLSIFISTWLTAAGFIHLVENSGDPWENFQNNQALTYWECVYLLMVTMSTVGYGDVY
AKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPN
LELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPS
WNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSAFVGLSFPTVCELCFVKLKLL
MIAIEYKSANRESRILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYCKACHDDITDPKRIKKCGCKRPKMSIYKRMRRACCFDCGRSER
DCSCMSGRVRGNVDTLERAFPLSSVSVNDCSTSFRAFEDEQPSTLSPKKKQRNGGMRNSPNTSPKLMRHDPLLIPGNDQIDNMDSNVKKY
DSTGMFHWCAPKEIEKVILTRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLVMPLRASNFHYHELKHIVFVGSIEYLKREWETLHNFPKV
SILPGTPLSRADLRAVNINLCDMCVILSANQNNIDDTSLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLR
QPSITTGVNIPIITELVNDTNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEE
NALRGGYSTPQTLANRDRCRVAQLALLDGPFADLGDGGCYGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPT
DLIFCLMQFDHNAGQSRASLSHSSHSSQSSSKKSSSVHSIPSTANRQNRPKSRESRDKQNATRMNRMGQEKKWFTDEPDNAYPRNIQIKP

--------------------------------------------------------------

>2469_2469_47_ADK-KCNMA1_ADK_chr10_76074503_ENST00000539909_KCNMA1_chr10_79011014_ENST00000404857_length(amino acids)=1131AA_BP=90
MAAAEEEPKPKKLKVEAPQALRENILFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELFDELVKKFKVEYHAGGSTQNSIKVA
QVVLVFALSIGALVIYFIDSSNPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWL
GLRFLRALRLIQFSEILQFLNILKTSNSIKLVNLLSIFISTWLTAAGFIHLVENSGDPWENFQNNQALTYWECVYLLMVTMSTVGYGDVY
AKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPN
LELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPS
WNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSAFVGLSFPTVCELCFVKLKLL
MIAIEYKSANRESRILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYCKACHDDITDPKRIKKCGCKRLEDEQPSTLSPKKKQRNGGMRN
SPNTSPKLMRHDPLLIPGNDQIDNMDSNVKKYDSTGMFHWCAPKEIEKVILVTGWMPYLGPRVLMTCLDIGVVCMPTDIQSTSPASIKKF
KETRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLVMPLRASNFHYHELKHIVFVGSIEYLKREWETLHNFPKVSILPGTPLSRADLRAVN
INLCDMCVILSANQNNIDDTSLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTGVNIPIITELV
NDTNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRD
RCRVAQLALLDGPFADLGDGGCYGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLIFCLMQFDHNAGQSR

--------------------------------------------------------------

>2469_2469_48_ADK-KCNMA1_ADK_chr10_76074503_ENST00000539909_KCNMA1_chr10_79011014_ENST00000406533_length(amino acids)=1152AA_BP=90
MAAAEEEPKPKKLKVEAPQALRENILFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELFDELVKKFKVEYHAGGSTQNSIKVA
QVVLVFALSIGALVIYFIDSSNPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWL
GLRFLRALRLIQFSEILQFLNILKTSNSIKLVNLLSIFISTWLTAAGFIHLVENSGDPWENFQNNQALTYWECVYLLMVTMSTVGYGDVY
AKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPN
LELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPS
WNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSAFVGLSFPTVCELCFVKLKLL
MIAIEYKSANRESRGRLSILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYCKACHDDITDPKRIKKCGCKRPKMSIYKRMRRACCFDCG
RSERDCSCMSGRVRGNVDTLERAFPLSSVSVNDCSTSFRAFEDEQPSTLSPKKKQRNGGMRNSPNTSPKLMRHDPLLIPGNDQIDNMDSN
VKKYDSTGMFHWCAPKEIEKVILTRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLVMPLRASNFHYHELKHIVFVGSIEYLKREWETLHN
FPKVSILPGTPLSRADLRAVNINLCDMCVILSANQNNIDDTSLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVH
GMLRQPSITTGVNIPIITELVNDTNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEAL
IAEENALRGGYSTPQTLANRDRCRVAQLALLDGPFADLGDGGCYGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFE

--------------------------------------------------------------

>2469_2469_49_ADK-KCNMA1_ADK_chr10_76074503_ENST00000541550_KCNMA1_chr10_79011014_ENST00000286627_length(amino acids)=1054AA_BP=55
MTSVRENILFGMGNPLLDISAVVDKDFLDKFDELVKKFKVEYHAGGSTQNSIKVAQVVLVFALSIGALVIYFIDSSNPIESCQNFYKDFT
LQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQFLNILKTSNSIKLVNLL
SIFISTWLTAAGFIHLVENSGDPWENFQNNQALTYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNR
KKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESA
DACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLAN
LFSMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSAFVGLSFPTVCELCFVKLKLLMIAIEYKSANRESRILINPGNHLKIQEGTLGFFIA
SDAKEVKRAFFYCKACHDDITDPKRIKKCGCKRLEDEQPSTLSPKKKQRNGGMRNSPNTSPKLMRHDPLLIPGNDQIDNMDSNVKKYDST
GMFHWCAPKEIEKVILTRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLVMPLRASNFHYHELKHIVFVGSIEYLKREWETLHNFPKVSIL
PGTPLSRADLRAVNINLCDMCVILSANQNNIDDTSLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPS
ITTGVNIPIITELVNDTNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENAL
RGGYSTPQTLANRDRCRVAQLALLDGPFADLGDGGCYGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLI

--------------------------------------------------------------

>2469_2469_50_ADK-KCNMA1_ADK_chr10_76074503_ENST00000541550_KCNMA1_chr10_79011014_ENST00000286628_length(amino acids)=1112AA_BP=55
MTSVRENILFGMGNPLLDISAVVDKDFLDKFDELVKKFKVEYHAGGSTQNSIKVAQVVLVFALSIGALVIYFIDSSNPIESCQNFYKDFT
LQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQFLNILKTSNSIKLVNLL
SIFISTWLTAAGFIHLVENSGDPWENFQNNQALTYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNR
KKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESA
DACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLAN
LFSMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSAFVGLSFPTVCELCFVKLKLLMIAIEYKSANRESRILINPGNHLKIQEGTLGFFIA
SDAKEVKRAFFYCKACHDDITDPKRIKKCGCKRPKMSIYKRMRRACCFDCGRSERDCSCMSGRVRGNVDTLERAFPLSSVSVNDCSTSFR
AFEDEQPSTLSPKKKQRNGGMRNSPNTSPKLMRHDPLLIPGNDQIDNMDSNVKKYDSTGMFHWCAPKEIEKVILTRSEAAMTVLSGHVVV
CIFGDVSSALIGLRNLVMPLRASNFHYHELKHIVFVGSIEYLKREWETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSANQNNID
DTSLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTGVNIPIITELVNDTNVQFLDQDDDDDPDT
ELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRDRCRVAQLALLDGPFADLG
DGGCYGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLIFCLMQFDHNAGQSRASLSHSSHSSQSSSKKSS

--------------------------------------------------------------

>2469_2469_51_ADK-KCNMA1_ADK_chr10_76074503_ENST00000541550_KCNMA1_chr10_79011014_ENST00000354353_length(amino acids)=1116AA_BP=55
MTSVRENILFGMGNPLLDISAVVDKDFLDKFDELVKKFKVEYHAGGSTQNSIKVAQVVLVFALSIGALVIYFIDSSNPIESCQNFYKDFT
LQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQFLNILKTSNSIKLVNLL
SIFISTWLTAAGFIHLVENSGDPWENFQNNQALTYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNR
KKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESA
DACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLAN
LFSMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSAFVGLSFPTVCELCFVKLKLLMIAIEYKSANRESRILINPGNHLKIQEGTLGFFIA
SDAKEVKRAFFYCKACHDDITDPKRIKKCGCKRRWEEHCSLWRLESKGNVRRLNYCRGQQTFSVKVKVAARSRYSKDPFEFKKETPNSRL
VTEPVEDEQPSTLSPKKKQRNGGMRNSPNTSPKLMRHDPLLIPGNDQIDNMDSNVKKYDSTGMFHWCAPKEIEKVILTRSEAAMTVLSGH
VVVCIFGDVSSALIGLRNLVMPLRASNFHYHELKHIVFVGSIEYLKREWETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSANQN
NIDDTSLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTGVNIPIITELVNDTNVQFLDQDDDDD
PDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRDRCRVAQLALLDGPFA
DLGDGGCYGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLIFCLMQFDHNAGQSRASLSHSSHSSQSSSK

--------------------------------------------------------------

>2469_2469_52_ADK-KCNMA1_ADK_chr10_76074503_ENST00000541550_KCNMA1_chr10_79011014_ENST00000372440_length(amino acids)=1053AA_BP=55
MTSVRENILFGMGNPLLDISAVVDKDFLDKFDELVKKFKVEYHAGGSTQNSIKVAQVVLVFALSIGALVIYFIDSSNPIESCQNFYKDFT
LQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQFLNILKTSNSIKLVNLL
SIFISTWLTAAGFIHLVENSGDPWENFQNNQALTYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNR
KKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESA
DACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLAN
LFSMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSAFVGLSFPTVCELCFVKLKLLMIAIEYKSANRESRILINPGNHLKIQEGTLGFFIA
SDAKEVKRAFFYCKACHDDITDPKRIKKCGCKRLEDEQPSTLSPKKKQRNGGMRNSPNTSPKLMRHDPLLIPGNDQIDNMDSNVKKYDST
GMFHWCAPKEIEKVILTRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLVMPLRASNFHYHELKHIVFVGSIEYLKREWETLHNFPKVSIL
PGTPLSRADLRAVNINLCDMCVILSANQNNIDDTSLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPS
ITTGVNIPIITELVNDTNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENAL
RGGYSTPQTLANRDRCRVAQLALLDGPFADLGDGGCYGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLI

--------------------------------------------------------------

>2469_2469_53_ADK-KCNMA1_ADK_chr10_76074503_ENST00000541550_KCNMA1_chr10_79011014_ENST00000372443_length(amino acids)=1081AA_BP=55
MTSVRENILFGMGNPLLDISAVVDKDFLDKFDELVKKFKVEYHAGGSTQNSIKVAQVVLVFALSIGALVIYFIDSSNPIESCQNFYKDFT
LQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQFLNILKTSNSIKLVNLL
SIFISTWLTAAGFIHLVENSGDPWENFQNNQALTYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNR
KKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESA
DACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLAN
LFSMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSAFVGLSFPTVCELCFVKLKLLMIAIEYKSANRESRILINPGNHLKIQEGTLGFFIA
SDAKEVKRAFFYCKACHDDITDPKRIKKCGCKRLEDEQPSTLSPKKKQRNGGMRNSPNTSPKLMRHDPLLIPGNDQIDNMDSNVKKYDST
GMFHWCAPKEIEKVILTRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLVMPLRASNFHYHELKHIVFVGSIEYLKREWETLHNFPKVSIL
PGTPLSRADLRAVNINLCDMCVILSANQNNIDDTSLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPS
ITTGVNIPIITELAKPGKLPLVSVNQEKNSGTHILMITELVNDTNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDN
ILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRDRCRVAQLALLDGPFADLGDGGCYGDLFCKALKTYNMLCFGIYRLRDAHL
STPSQCTKRYVITNPPYEFELVPTDLIFCLMQFDHNAGQSRASLSHSSHSSQSSSKKSSSVHSIPSTANRQNRPKSRESRDKQNRKEMVY

--------------------------------------------------------------

>2469_2469_54_ADK-KCNMA1_ADK_chr10_76074503_ENST00000541550_KCNMA1_chr10_79011014_ENST00000404771_length(amino acids)=1164AA_BP=55
MTSVRENILFGMGNPLLDISAVVDKDFLDKFDELVKKFKVEYHAGGSTQNSIKVAQVVLVFALSIGALVIYFIDSSNPIESCQNFYKDFT
LQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQFLNILKTSNSIKLVNLL
SIFISTWLTAAGFIHLVENSGDPWENFQNNQALTYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNR
KKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESA
DACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLAN
LFSMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSAFVGLSFPTVCELCFVKLKLLMIAIEYKSANRESRILINPGNHLKIQEGTLGFFIA
SDAKEVKRAFFYCKACHDDITDPKRIKKCGCKRPKMSIYKRMRRACCFDCGRSERDCSCMSGRVRGNVDTLERAFPLSSVSVNDCSTSFR
AFEDEQPSTLSPKKKQRNGGMRNSPNTSPKLMRHDPLLIPGNDQIDNMDSNVKKYDSTGMFHWCAPKEIEKVILTRSEAAMTVLSGHVVV
CIFGDVSSALIGLRNLVMPLRASNFHYHELKHIVFVGSIEYLKREWETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSANQNNID
DTSLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTGVNIPIITELVNDTNVQFLDQDDDDDPDT
ELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRDRCRVAQLALLDGPFADLG
DGGCYGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLIFCLMQFDHNAGQSRASLSHSSHSSQSSSKKSS

--------------------------------------------------------------

>2469_2469_55_ADK-KCNMA1_ADK_chr10_76074503_ENST00000541550_KCNMA1_chr10_79011014_ENST00000404857_length(amino acids)=1096AA_BP=55
MTSVRENILFGMGNPLLDISAVVDKDFLDKFDELVKKFKVEYHAGGSTQNSIKVAQVVLVFALSIGALVIYFIDSSNPIESCQNFYKDFT
LQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQFLNILKTSNSIKLVNLL
SIFISTWLTAAGFIHLVENSGDPWENFQNNQALTYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNR
KKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESA
DACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLAN
LFSMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSAFVGLSFPTVCELCFVKLKLLMIAIEYKSANRESRILINPGNHLKIQEGTLGFFIA
SDAKEVKRAFFYCKACHDDITDPKRIKKCGCKRLEDEQPSTLSPKKKQRNGGMRNSPNTSPKLMRHDPLLIPGNDQIDNMDSNVKKYDST
GMFHWCAPKEIEKVILVTGWMPYLGPRVLMTCLDIGVVCMPTDIQSTSPASIKKFKETRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLV
MPLRASNFHYHELKHIVFVGSIEYLKREWETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSANQNNIDDTSLQDKECILASLNIK
SMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTGVNIPIITELVNDTNVQFLDQDDDDDPDTELYLTQPFACGTAFAVS
VLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRDRCRVAQLALLDGPFADLGDGGCYGDLFCKALKTYN
MLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLIFCLMQFDHNAGQSRASLSHSSHSSQSSSKKSSSVHSIPSTANRQNRPKS

--------------------------------------------------------------

>2469_2469_56_ADK-KCNMA1_ADK_chr10_76074503_ENST00000541550_KCNMA1_chr10_79011014_ENST00000406533_length(amino acids)=1117AA_BP=55
MTSVRENILFGMGNPLLDISAVVDKDFLDKFDELVKKFKVEYHAGGSTQNSIKVAQVVLVFALSIGALVIYFIDSSNPIESCQNFYKDFT
LQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQFLNILKTSNSIKLVNLL
SIFISTWLTAAGFIHLVENSGDPWENFQNNQALTYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNR
KKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESA
DACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLAN
LFSMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSAFVGLSFPTVCELCFVKLKLLMIAIEYKSANRESRGRLSILINPGNHLKIQEGTLG
FFIASDAKEVKRAFFYCKACHDDITDPKRIKKCGCKRPKMSIYKRMRRACCFDCGRSERDCSCMSGRVRGNVDTLERAFPLSSVSVNDCS
TSFRAFEDEQPSTLSPKKKQRNGGMRNSPNTSPKLMRHDPLLIPGNDQIDNMDSNVKKYDSTGMFHWCAPKEIEKVILTRSEAAMTVLSG
HVVVCIFGDVSSALIGLRNLVMPLRASNFHYHELKHIVFVGSIEYLKREWETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSANQ
NNIDDTSLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTGVNIPIITELVNDTNVQFLDQDDDD
DPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRDRCRVAQLALLDGPF
ADLGDGGCYGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLIFCLMQFDHNAGQSRASLSHSSHSSQSSS

--------------------------------------------------------------

Top

Fusion Protein Functional Features

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr10:76074503/chr10:79011014)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
ADK P55263	KCNMA1 Q12791
FUNCTION: ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives. Serves as a potential regulator of concentrations of extracellular adenosine and intracellular adenine nucleotides.	FUNCTION: Potassium channel activated by both membrane depolarization or increase in cytosolic Ca(2+) that mediates export of K(+) (PubMed:29330545, PubMed:31152168). It is also activated by the concentration of cytosolic Mg(2+). Its activation dampens the excitatory events that elevate the cytosolic Ca(2+) concentration and/or depolarize the cell membrane. It therefore contributes to repolarization of the membrane potential. Plays a key role in controlling excitability in a number of systems, such as regulation of the contraction of smooth muscle, the tuning of hair cells in the cochlea, regulation of transmitter release, and innate immunity. In smooth muscles, its activation by high level of Ca(2+), caused by ryanodine receptors in the sarcoplasmic reticulum, regulates the membrane potential. In cochlea cells, its number and kinetic properties partly determine the characteristic frequency of each hair cell and thereby helps to establish a tonotopic map. Kinetics of KCNMA1 channels are determined by alternative splicing, phosphorylation status and its combination with modulating beta subunits. Highly sensitive to both iberiotoxin (IbTx) and charybdotoxin (CTX). {ECO:0000269\|PubMed:29330545, ECO:0000269\|PubMed:31152168}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page
* Minus value of BPloci means that the break pointn is located before the CDS.

- Retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

ADK

chr10:75984349

chr10:78778857

ENST00000286621

8_16

64.66666666666667

363.0

Motif

Nuclear localization signal

Hgene

ADK

chr10:75984349

chr10:78778857

ENST00000372734

8_16

47.666666666666664

346.0

Motif

Nuclear localization signal

Hgene

ADK

chr10:75984349

chr10:78778857

ENST00000539909

8_16

64.66666666666667

306.0

Motif

Nuclear localization signal

Hgene

ADK

chr10:76074503

chr10:79011014

ENST00000286621

8_16

91.0

363.0

Motif

Nuclear localization signal

Hgene

ADK

chr10:76074503

chr10:79011014

ENST00000372734

8_16

74.0

346.0

Motif

Nuclear localization signal

Hgene

ADK

chr10:76074503

chr10:79011014

ENST00000539909

8_16

91.0

306.0

Motif

Nuclear localization signal

Hgene

ADK

chr10:76074503

chr10:79011014

ENST00000541550

8_16

56.0

328.0

Motif

Nuclear localization signal

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000480683

13_20

169.0

Compositional bias

Note=Poly-Gly

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000480683

39_60

169.0

Compositional bias

Note=Poly-Ser

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000480683

4_10

169.0

Compositional bias

Note=Poly-Gly

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000480683

13_20

169.0

Compositional bias

Note=Poly-Gly

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000480683

39_60

169.0

Compositional bias

Note=Poly-Ser

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000480683

4_10

169.0

Compositional bias

Note=Poly-Gly

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000480683

415_558

169.0

Domain

Note=RCK N-terminal

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000286627

415_558

180.0

1179.0

Domain

Note=RCK N-terminal

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000286628

415_558

180.0

1237.0

Domain

Note=RCK N-terminal

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000404857

415_558

180.0

1220.0

Domain

Note=RCK N-terminal

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000480683

415_558

169.0

Domain

Note=RCK N-terminal

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000480683

336_358

169.0

Intramembrane

Pore-forming%3B Name%3DP region

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000286627

336_358

180.0

1179.0

Intramembrane

Pore-forming%3B Name%3DP region

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000286628

336_358

180.0

1237.0

Intramembrane

Pore-forming%3B Name%3DP region

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000404857

336_358

180.0

1220.0

Intramembrane

Pore-forming%3B Name%3DP region

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000480683

336_358

169.0

Intramembrane

Pore-forming%3B Name%3DP region

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000286627

1003_1025

642.6666666666666

1179.0

Motif

Note=Calcium bowl

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000286628

1003_1025

642.6666666666666

1237.0

Motif

Note=Calcium bowl

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000404857

1003_1025

642.6666666666666

1220.0

Motif

Note=Calcium bowl

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000480683

1003_1025

169.0

Motif

Note=Calcium bowl

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000480683

352_355

169.0

Motif

Note=Selectivity for potassium

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000286627

1003_1025

180.0

1179.0

Motif

Note=Calcium bowl

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000286627

352_355

180.0

1179.0

Motif

Note=Selectivity for potassium

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000286628

1003_1025

180.0

1237.0

Motif

Note=Calcium bowl

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000286628

352_355

180.0

1237.0

Motif

Note=Selectivity for potassium

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000404857

1003_1025

180.0

1220.0

Motif

Note=Calcium bowl

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000404857

352_355

180.0

1220.0

Motif

Note=Selectivity for potassium

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000480683

1003_1025

169.0

Motif

Note=Calcium bowl

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000480683

352_355

169.0

Motif

Note=Selectivity for potassium

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000286627

1032_1052

642.6666666666666

1179.0

Region

Note=Segment S10

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000286627

677_681

642.6666666666666

1179.0

Region

Note=Heme-binding motif

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000286627

837_857

642.6666666666666

1179.0

Region

Note=Segment S9

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000286628

1032_1052

642.6666666666666

1237.0

Region

Note=Segment S10

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000286628

677_681

642.6666666666666

1237.0

Region

Note=Heme-binding motif

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000286628

837_857

642.6666666666666

1237.0

Region

Note=Segment S9

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000404857

1032_1052

642.6666666666666

1220.0

Region

Note=Segment S10

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000404857

677_681

642.6666666666666

1220.0

Region

Note=Heme-binding motif

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000404857

837_857

642.6666666666666

1220.0

Region

Note=Segment S9

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000480683

1032_1052

169.0

Region

Note=Segment S10

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000480683

556_576

169.0

Region

Note=Segment S7

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000480683

613_633

169.0

Region

Note=Segment S8

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000480683

677_681

169.0

Region

Note=Heme-binding motif

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000480683

837_857

169.0

Region

Note=Segment S9

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000286627

1032_1052

180.0

1179.0

Region

Note=Segment S10

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000286627

556_576

180.0

1179.0

Region

Note=Segment S7

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000286627

613_633

180.0

1179.0

Region

Note=Segment S8

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000286627

677_681

180.0

1179.0

Region

Note=Heme-binding motif

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000286627

837_857

180.0

1179.0

Region

Note=Segment S9

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000286628

1032_1052

180.0

1237.0

Region

Note=Segment S10

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000286628

556_576

180.0

1237.0

Region

Note=Segment S7

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000286628

613_633

180.0

1237.0

Region

Note=Segment S8

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000286628

677_681

180.0

1237.0

Region

Note=Heme-binding motif

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000286628

837_857

180.0

1237.0

Region

Note=Segment S9

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000404857

1032_1052

180.0

1220.0

Region

Note=Segment S10

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000404857

556_576

180.0

1220.0

Region

Note=Segment S7

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000404857

613_633

180.0

1220.0

Region

Note=Segment S8

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000404857

677_681

180.0

1220.0

Region

Note=Heme-binding motif

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000404857

837_857

180.0

1220.0

Region

Note=Segment S9

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000480683

1032_1052

169.0

Region

Note=Segment S10

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000480683

556_576

169.0

Region

Note=Segment S7

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000480683

613_633

169.0

Region

Note=Segment S8

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000480683

677_681

169.0

Region

Note=Heme-binding motif

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000480683

837_857

169.0

Region

Note=Segment S9

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000480683

108_178

169.0

Topological domain

Cytoplasmic

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000480683

1_86

169.0

Topological domain

Extracellular

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000480683

200_214

169.0

Topological domain

Extracellular

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000480683

236_239

169.0

Topological domain

Cytoplasmic

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000480683

261_264

169.0

Topological domain

Extracellular

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000480683

286_300

169.0

Topological domain

Cytoplasmic

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000480683

322_335

169.0

Topological domain

Extracellular

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000480683

359_367

169.0

Topological domain

Extracellular

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000480683

389_1236

169.0

Topological domain

Cytoplasmic

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000286627

200_214

180.0

1179.0

Topological domain

Extracellular

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000286627

236_239

180.0

1179.0

Topological domain

Cytoplasmic

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000286627

261_264

180.0

1179.0

Topological domain

Extracellular

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000286627

286_300

180.0

1179.0

Topological domain

Cytoplasmic

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000286627

322_335

180.0

1179.0

Topological domain

Extracellular

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000286627

359_367

180.0

1179.0

Topological domain

Extracellular

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000286627

389_1236

180.0

1179.0

Topological domain

Cytoplasmic

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000286628

200_214

180.0

1237.0

Topological domain

Extracellular

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000286628

236_239

180.0

1237.0

Topological domain

Cytoplasmic

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000286628

261_264

180.0

1237.0

Topological domain

Extracellular

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000286628

286_300

180.0

1237.0

Topological domain

Cytoplasmic

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000286628

322_335

180.0

1237.0

Topological domain

Extracellular

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000286628

359_367

180.0

1237.0

Topological domain

Extracellular

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000286628

389_1236

180.0

1237.0

Topological domain

Cytoplasmic

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000404857

200_214

180.0

1220.0

Topological domain

Extracellular

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000404857

236_239

180.0

1220.0

Topological domain

Cytoplasmic

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000404857

261_264

180.0

1220.0

Topological domain

Extracellular

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000404857

286_300

180.0

1220.0

Topological domain

Cytoplasmic

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000404857

322_335

180.0

1220.0

Topological domain

Extracellular

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000404857

359_367

180.0

1220.0

Topological domain

Extracellular

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000404857

389_1236

180.0

1220.0

Topological domain

Cytoplasmic

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000480683

108_178

169.0

Topological domain

Cytoplasmic

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000480683

1_86

169.0

Topological domain

Extracellular

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000480683

200_214

169.0

Topological domain

Extracellular

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000480683

236_239

169.0

Topological domain

Cytoplasmic

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000480683

261_264

169.0

Topological domain

Extracellular

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000480683

286_300

169.0

Topological domain

Cytoplasmic

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000480683

322_335

169.0

Topological domain

Extracellular

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000480683

359_367

169.0

Topological domain

Extracellular

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000480683

389_1236

169.0

Topological domain

Cytoplasmic

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000480683

179_199

169.0

Transmembrane

Helical%3B Name%3DSegment S1

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000480683

215_235

169.0

Transmembrane

Helical%3B Name%3DSegment S2

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000480683

240_260

169.0

Transmembrane

Helical%3B Name%3DSegment S3

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000480683

265_285

169.0

Transmembrane

Helical%3B Name%3DSegment S4

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000480683

301_321

169.0

Transmembrane

Helical%3B Name%3DSegment S5

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000480683

368_388

169.0

Transmembrane

Helical%3B Name%3DSegment S6

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000480683

87_107

169.0

Transmembrane

Helical%3B Name%3DSegment S0

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000286627

179_199

180.0

1179.0

Transmembrane

Helical%3B Name%3DSegment S1

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000286627

215_235

180.0

1179.0

Transmembrane

Helical%3B Name%3DSegment S2

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000286627

240_260

180.0

1179.0

Transmembrane

Helical%3B Name%3DSegment S3

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000286627

265_285

180.0

1179.0

Transmembrane

Helical%3B Name%3DSegment S4

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000286627

301_321

180.0

1179.0

Transmembrane

Helical%3B Name%3DSegment S5

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000286627

368_388

180.0

1179.0

Transmembrane

Helical%3B Name%3DSegment S6

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000286628

179_199

180.0

1237.0

Transmembrane

Helical%3B Name%3DSegment S1

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000286628

215_235

180.0

1237.0

Transmembrane

Helical%3B Name%3DSegment S2

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000286628

240_260

180.0

1237.0

Transmembrane

Helical%3B Name%3DSegment S3

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000286628

265_285

180.0

1237.0

Transmembrane

Helical%3B Name%3DSegment S4

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000286628

301_321

180.0

1237.0

Transmembrane

Helical%3B Name%3DSegment S5

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000286628

368_388

180.0

1237.0

Transmembrane

Helical%3B Name%3DSegment S6

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000404857

179_199

180.0

1220.0

Transmembrane

Helical%3B Name%3DSegment S1

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000404857

215_235

180.0

1220.0

Transmembrane

Helical%3B Name%3DSegment S2

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000404857

240_260

180.0

1220.0

Transmembrane

Helical%3B Name%3DSegment S3

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000404857

265_285

180.0

1220.0

Transmembrane

Helical%3B Name%3DSegment S4

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000404857

301_321

180.0

1220.0

Transmembrane

Helical%3B Name%3DSegment S5

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000404857

368_388

180.0

1220.0

Transmembrane

Helical%3B Name%3DSegment S6

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000480683

179_199

169.0

Transmembrane

Helical%3B Name%3DSegment S1

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000480683

215_235

169.0

Transmembrane

Helical%3B Name%3DSegment S2

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000480683

240_260

169.0

Transmembrane

Helical%3B Name%3DSegment S3

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000480683

265_285

169.0

Transmembrane

Helical%3B Name%3DSegment S4

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000480683

301_321

169.0

Transmembrane

Helical%3B Name%3DSegment S5

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000480683

368_388

169.0

Transmembrane

Helical%3B Name%3DSegment S6

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000480683

87_107

169.0

Transmembrane

Helical%3B Name%3DSegment S0

- Not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

ADK

chr10:75984349

chr10:78778857

ENST00000541550

8_16

328.0

Motif

Nuclear localization signal

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000286627

13_20

642.6666666666666

1179.0

Compositional bias

Note=Poly-Gly

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000286627

39_60

642.6666666666666

1179.0

Compositional bias

Note=Poly-Ser

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000286627

4_10

642.6666666666666

1179.0

Compositional bias

Note=Poly-Gly

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000286628

13_20

642.6666666666666

1237.0

Compositional bias

Note=Poly-Gly

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000286628

39_60

642.6666666666666

1237.0

Compositional bias

Note=Poly-Ser

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000286628

4_10

642.6666666666666

1237.0

Compositional bias

Note=Poly-Gly

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000404857

13_20

642.6666666666666

1220.0

Compositional bias

Note=Poly-Gly

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000404857

39_60

642.6666666666666

1220.0

Compositional bias

Note=Poly-Ser

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000404857

4_10

642.6666666666666

1220.0

Compositional bias

Note=Poly-Gly

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000286627

13_20

180.0

1179.0

Compositional bias

Note=Poly-Gly

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000286627

39_60

180.0

1179.0

Compositional bias

Note=Poly-Ser

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000286627

4_10

180.0

1179.0

Compositional bias

Note=Poly-Gly

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000286628

13_20

180.0

1237.0

Compositional bias

Note=Poly-Gly

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000286628

39_60

180.0

1237.0

Compositional bias

Note=Poly-Ser

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000286628

4_10

180.0

1237.0

Compositional bias

Note=Poly-Gly

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000404857

13_20

180.0

1220.0

Compositional bias

Note=Poly-Gly

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000404857

39_60

180.0

1220.0

Compositional bias

Note=Poly-Ser

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000404857

4_10

180.0

1220.0

Compositional bias

Note=Poly-Gly

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000286627

415_558

642.6666666666666

1179.0

Domain

Note=RCK N-terminal

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000286628

415_558

642.6666666666666

1237.0

Domain

Note=RCK N-terminal

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000404857

415_558

642.6666666666666

1220.0

Domain

Note=RCK N-terminal

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000286627

336_358

642.6666666666666

1179.0

Intramembrane

Pore-forming%3B Name%3DP region

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000286628

336_358

642.6666666666666

1237.0

Intramembrane

Pore-forming%3B Name%3DP region

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000404857

336_358

642.6666666666666

1220.0

Intramembrane

Pore-forming%3B Name%3DP region

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000286627

352_355

642.6666666666666

1179.0

Motif

Note=Selectivity for potassium

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000286628

352_355

642.6666666666666

1237.0

Motif

Note=Selectivity for potassium

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000404857

352_355

642.6666666666666

1220.0

Motif

Note=Selectivity for potassium

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000286627

556_576

642.6666666666666

1179.0

Region

Note=Segment S7

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000286627

613_633

642.6666666666666

1179.0

Region

Note=Segment S8

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000286628

556_576

642.6666666666666

1237.0

Region

Note=Segment S7

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000286628

613_633

642.6666666666666

1237.0

Region

Note=Segment S8

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000404857

556_576

642.6666666666666

1220.0

Region

Note=Segment S7

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000404857

613_633

642.6666666666666

1220.0

Region

Note=Segment S8

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000286627

108_178

642.6666666666666

1179.0

Topological domain

Cytoplasmic

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000286627

1_86

642.6666666666666

1179.0

Topological domain

Extracellular

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000286627

200_214

642.6666666666666

1179.0

Topological domain

Extracellular

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000286627

236_239

642.6666666666666

1179.0

Topological domain

Cytoplasmic

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000286627

261_264

642.6666666666666

1179.0

Topological domain

Extracellular

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000286627

286_300

642.6666666666666

1179.0

Topological domain

Cytoplasmic

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000286627

322_335

642.6666666666666

1179.0

Topological domain

Extracellular

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000286627

359_367

642.6666666666666

1179.0

Topological domain

Extracellular

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000286627

389_1236

642.6666666666666

1179.0

Topological domain

Cytoplasmic

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000286628

108_178

642.6666666666666

1237.0

Topological domain

Cytoplasmic

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000286628

1_86

642.6666666666666

1237.0

Topological domain

Extracellular

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000286628

200_214

642.6666666666666

1237.0

Topological domain

Extracellular

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000286628

236_239

642.6666666666666

1237.0

Topological domain

Cytoplasmic

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000286628

261_264

642.6666666666666

1237.0

Topological domain

Extracellular

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000286628

286_300

642.6666666666666

1237.0

Topological domain

Cytoplasmic

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000286628

322_335

642.6666666666666

1237.0

Topological domain

Extracellular

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000286628

359_367

642.6666666666666

1237.0

Topological domain

Extracellular

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000286628

389_1236

642.6666666666666

1237.0

Topological domain

Cytoplasmic

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000404857

108_178

642.6666666666666

1220.0

Topological domain

Cytoplasmic

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000404857

1_86

642.6666666666666

1220.0

Topological domain

Extracellular

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000404857

200_214

642.6666666666666

1220.0

Topological domain

Extracellular

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000404857

236_239

642.6666666666666

1220.0

Topological domain

Cytoplasmic

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000404857

261_264

642.6666666666666

1220.0

Topological domain

Extracellular

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000404857

286_300

642.6666666666666

1220.0

Topological domain

Cytoplasmic

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000404857

322_335

642.6666666666666

1220.0

Topological domain

Extracellular

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000404857

359_367

642.6666666666666

1220.0

Topological domain

Extracellular

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000404857

389_1236

642.6666666666666

1220.0

Topological domain

Cytoplasmic

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000286627

108_178

180.0

1179.0

Topological domain

Cytoplasmic

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000286627

1_86

180.0

1179.0

Topological domain

Extracellular

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000286628

108_178

180.0

1237.0

Topological domain

Cytoplasmic

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000286628

1_86

180.0

1237.0

Topological domain

Extracellular

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000404857

108_178

180.0

1220.0

Topological domain

Cytoplasmic

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000404857

1_86

180.0

1220.0

Topological domain

Extracellular

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000286627

179_199

642.6666666666666

1179.0

Transmembrane

Helical%3B Name%3DSegment S1

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000286627

215_235

642.6666666666666

1179.0

Transmembrane

Helical%3B Name%3DSegment S2

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000286627

240_260

642.6666666666666

1179.0

Transmembrane

Helical%3B Name%3DSegment S3

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000286627

265_285

642.6666666666666

1179.0

Transmembrane

Helical%3B Name%3DSegment S4

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000286627

301_321

642.6666666666666

1179.0

Transmembrane

Helical%3B Name%3DSegment S5

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000286627

368_388

642.6666666666666

1179.0

Transmembrane

Helical%3B Name%3DSegment S6

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000286627

87_107

642.6666666666666

1179.0

Transmembrane

Helical%3B Name%3DSegment S0

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000286628

179_199

642.6666666666666

1237.0

Transmembrane

Helical%3B Name%3DSegment S1

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000286628

215_235

642.6666666666666

1237.0

Transmembrane

Helical%3B Name%3DSegment S2

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000286628

240_260

642.6666666666666

1237.0

Transmembrane

Helical%3B Name%3DSegment S3

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000286628

265_285

642.6666666666666

1237.0

Transmembrane

Helical%3B Name%3DSegment S4

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000286628

301_321

642.6666666666666

1237.0

Transmembrane

Helical%3B Name%3DSegment S5

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000286628

368_388

642.6666666666666

1237.0

Transmembrane

Helical%3B Name%3DSegment S6

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000286628

87_107

642.6666666666666

1237.0

Transmembrane

Helical%3B Name%3DSegment S0

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000404857

179_199

642.6666666666666

1220.0

Transmembrane

Helical%3B Name%3DSegment S1

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000404857

215_235

642.6666666666666

1220.0

Transmembrane

Helical%3B Name%3DSegment S2

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000404857

240_260

642.6666666666666

1220.0

Transmembrane

Helical%3B Name%3DSegment S3

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000404857

265_285

642.6666666666666

1220.0

Transmembrane

Helical%3B Name%3DSegment S4

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000404857

301_321

642.6666666666666

1220.0

Transmembrane

Helical%3B Name%3DSegment S5

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000404857

368_388

642.6666666666666

1220.0

Transmembrane

Helical%3B Name%3DSegment S6

Tgene

KCNMA1

chr10:75984349

chr10:78778857

ENST00000404857

87_107

642.6666666666666

1220.0

Transmembrane

Helical%3B Name%3DSegment S0

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000286627

87_107

180.0

1179.0

Transmembrane

Helical%3B Name%3DSegment S0

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000286628

87_107

180.0

1237.0

Transmembrane

Helical%3B Name%3DSegment S0

Tgene

KCNMA1

chr10:76074503

chr10:79011014

ENST00000404857

87_107

180.0

1220.0

Transmembrane

Helical%3B Name%3DSegment S0

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Fusion Protein Structures

PDB and CIF files of the predicted fusion proteins
* Here we show the 3D structure of the fusion proteins using Mol*. AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Model confidence is shown from the pLDDT values per residue. pLDDT corresponds to the model’s prediction of its score on the local Distance Difference Test. It is a measure of local accuracy (from AlphfaFold website). To color code individual residues, we transformed individual PDB files into CIF format.

Fusion protein PDB link (fusion AA seq ID in FusionPDB)	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	AA seq	Len(AA seq)
PDB file >>>1927_ADK_76074503_KCNMA1_79011014_ranked_0.pdb	ADK	75984349	76074503	ENST00000406533	KCNMA1	chr10	79011014	-	MAAAEEEPKPKKLKVEAPQALRENILFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELFDELVKKFKVEYHAGGSTQNSIKVA QVVLVFALSIGALVIYFIDSSNPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWL GLRFLRALRLIQFSEILQFLNILKTSNSIKLVNLLSIFISTWLTAAGFIHLVENSGDPWENFQNNQALTYWECVYLLMVTMSTVGYGDVY AKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPN LELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPS WNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSAFVGLSFPTVCELCFVKLKLL MIAIEYKSANRESRILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYCKACHDDITDPKRIKKCGCKRPKMSIYKRMRRACCFDCGRSER DCSCMSGRVRGNVDTLERAFPLSSVSVNDCSTSFRAFEDEQPSTLSPKKKQRNGGMRNSPNTSPKLMRHDPLLIPGNDQIDNMDSNVKKY DSTGMFHWCAPKEIEKVILTRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLVMPLRASNFHYHELKHIVFVGSIEYLKREWETLHNFPKV SILPGTPLSRADLRAVNINLCDMCVILSANQNNIDDTSLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLR QPSITTGVNIPIITELVNDTNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEE NALRGGYSTPQTLANRDRCRVAQLALLDGPFADLGDGGCYGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPT DLIFCLMQFDHNAGQSRASLSHSSHSSQSSSKKSSSVHSIPSTANRQNRPKSRESRDKQNATRMNRMGQEKKWFTDEPDNAYPRNIQIKP	1199

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pLDDT score distribution

pLDDT score distribution of the predicted wild-type structures of two partner proteins from AlphaFold2
* AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100.

ADK_pLDDT.png

KCNMA1_pLDDT.png

pLDDT score distribution of the predicted fusion protein structures from AlphaFold2
* AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100.

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Ramachandran Plot of Fusion Protein Structure

Ramachandran plot of the torsional angles - phi (φ)and psi (ψ) - of the residues (amino acids) contained in this fusion protein peptide.

Fusion AA seq ID in FusionPDB and their Ramachandran plots

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Fusion Protein-Protein Interaction

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type from validated records (BIOGRID-3.4.160)

Gene

PPI interactors

Protein-protein interactors based on sequence similarity (STRING)

Gene	STRING network
ADK
KCNMA1

- Retained interactions in fusion protein (protein functional feature from UniProt).

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost interactions due to fusion (protein functional feature from UniProt).

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

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Related Drugs to ADK-KCNMA1

Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)

Hgene

Tgene

Drug

Source

PMID

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Related Diseases to ADK-KCNMA1

Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)

Hgene

Tgene

Disease

Source

PMID

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source