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Center for Computational Systems Medicine level1
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Fusion Gene Summary

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Fusion Gene Sample Information

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Fusion ORF Analysis

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Fusion Amino Acid Sequences

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Fusion Protein Functional Features

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Fusion Protein-Protein Interaction

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Related drugs with this fusion protein

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Related disease with this fusion protein

Fusion Protein:ENDOV-IKZF3

Fusion Protein Summary

check button Fusion gene summary
Fusion partner gene informationFusion gene name: ENDOV-IKZF3
FusionPDB ID: 26558
FusionGDB2.0 ID: 26558
HgeneTgene
Gene symbol

ENDOV

IKZF3

Gene ID

284131

22806

Gene nameendonuclease VIKAROS family zinc finger 3
Synonyms-AIO|AIOLOS|ZNFN1A3
Cytomap

17q25.3

17q12-q21.1

Type of geneprotein-codingprotein-coding
Descriptionendonuclease VhEndoVinosine-specific endoribonucleasezinc finger protein Aioloszinc finger DNA binding protein Aioloszinc finger protein, subfamily 1A, 3 (Aiolos)
Modification date2020031320200327
UniProtAcc

Q8N8Q3

Q9UKT9

Ensembl transtripts involved in fusion geneENST idsENST00000323854, ENST00000517295, 
ENST00000517795, ENST00000518137, 
ENST00000518901, ENST00000520367, 
ENST00000522751, ENST00000518644, 
ENST00000518907, ENST00000520284, 
ENST00000521847, ENST00000523999, 
ENST00000346872, ENST00000377944, 
ENST00000377945, ENST00000377952, 
ENST00000377958, ENST00000394189, 
ENST00000439016, ENST00000439167, 
ENST00000535189, ENST00000583368, 
ENST00000346243, ENST00000350532, 
ENST00000351680, ENST00000467757, 
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)* DoF score4 X 4 X 3=4834 X 12 X 14=5712
# samples 449
** MAII scorelog2(4/48*10)=-0.263034405833794
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(49/5712*10)=-3.54314232502653
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context (manual curation of fusion genes in FusionPDB)

PubMed: ENDOV [Title/Abstract] AND IKZF3 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)ENDOV(78403631)-IKZF3(37922746), # samples:2
Anticipated loss of major functional domain due to fusion event.ENDOV-IKZF3 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ENDOV-IKZF3 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ENDOV-IKZF3 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
ENDOV-IKZF3 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
ENDOV-IKZF3 seems lost the major protein functional domain in Tgene partner, which is a epigenetic factor due to the frame-shifted ORF.
ENDOV-IKZF3 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
ENDOV-IKZF3 seems lost the major protein functional domain in Tgene partner, which is a transcription factor due to the frame-shifted ORF.
ENDOV-IKZF3 seems lost the major protein functional domain in Tgene partner, which is a tumor suppressor due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across ENDOV (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across IKZF3 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure


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Fusion Gene Sample Information

check buttonFusion gene information from FusionGDB2.0.
check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-A2-A0T1-01AENDOVchr17

78403631

-IKZF3chr17

37922746

-
ChimerDB4BRCATCGA-A2-A0T1-01AENDOVchr17

78403631

+IKZF3chr17

37922746

-


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Fusion ORF Analysis


check buttonFusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000520367ENDOVchr1778403631+ENST00000346872IKZF3chr1737922746-2280731281434468
ENST00000520367ENDOVchr1778403631+ENST00000394189IKZF3chr1737922746-1941731281434468
ENST00000520367ENDOVchr1778403631+ENST00000439167IKZF3chr1737922746-1941731281434468
ENST00000520367ENDOVchr1778403631+ENST00000535189IKZF3chr1737922746-1941731281434468
ENST00000520367ENDOVchr1778403631+ENST00000377944IKZF3chr1737922746-1941731281434468
ENST00000520367ENDOVchr1778403631+ENST00000377945IKZF3chr1737922746-1941731281434468
ENST00000520367ENDOVchr1778403631+ENST00000377952IKZF3chr1737922746-1941731281434468
ENST00000520367ENDOVchr1778403631+ENST00000377958IKZF3chr1737922746-1941731281434468
ENST00000518137ENDOVchr1778403631+ENST00000346872IKZF3chr1737922746-2415866281569513
ENST00000518137ENDOVchr1778403631+ENST00000394189IKZF3chr1737922746-2076866281569513
ENST00000518137ENDOVchr1778403631+ENST00000439167IKZF3chr1737922746-2076866281569513
ENST00000518137ENDOVchr1778403631+ENST00000535189IKZF3chr1737922746-2076866281569513
ENST00000518137ENDOVchr1778403631+ENST00000377944IKZF3chr1737922746-2076866281569513
ENST00000518137ENDOVchr1778403631+ENST00000377945IKZF3chr1737922746-2076866281569513
ENST00000518137ENDOVchr1778403631+ENST00000377952IKZF3chr1737922746-2076866281569513
ENST00000518137ENDOVchr1778403631+ENST00000377958IKZF3chr1737922746-2076866281569513
ENST00000323854ENDOVchr1778403631+ENST00000346243IKZF3chr1737922746-1871116710521870273
ENST00000323854ENDOVchr1778403631+ENST00000350532IKZF3chr1737922746-1871116710521870273
ENST00000323854ENDOVchr1778403631+ENST00000351680IKZF3chr1737922746-1871116710521870273
ENST00000323854ENDOVchr1778403631+ENST00000467757IKZF3chr1737922746-1871116710521870273
ENST00000522751ENDOVchr1778403631+ENST00000439016IKZF3chr1737922746-2120141613102119270
ENST00000522751ENDOVchr1778403631+ENST00000583368IKZF3chr1737922746-2414141613102119269
ENST00000517795ENDOVchr1778403631+ENST00000346872IKZF3chr1737922746-21435941971297366
ENST00000517795ENDOVchr1778403631+ENST00000394189IKZF3chr1737922746-18045941971297366
ENST00000517795ENDOVchr1778403631+ENST00000439167IKZF3chr1737922746-18045941971297366
ENST00000517795ENDOVchr1778403631+ENST00000535189IKZF3chr1737922746-18045941971297366
ENST00000517795ENDOVchr1778403631+ENST00000377944IKZF3chr1737922746-18045941971297366
ENST00000517795ENDOVchr1778403631+ENST00000377945IKZF3chr1737922746-18045941971297366
ENST00000517795ENDOVchr1778403631+ENST00000377952IKZF3chr1737922746-18045941971297366
ENST00000517795ENDOVchr1778403631+ENST00000377958IKZF3chr1737922746-18045941971297366
ENST00000518901ENDOVchr1778403631+ENST00000346872IKZF3chr1737922746-2148599821302406
ENST00000518901ENDOVchr1778403631+ENST00000394189IKZF3chr1737922746-1809599821302406
ENST00000518901ENDOVchr1778403631+ENST00000439167IKZF3chr1737922746-1809599821302406
ENST00000518901ENDOVchr1778403631+ENST00000535189IKZF3chr1737922746-1809599821302406
ENST00000518901ENDOVchr1778403631+ENST00000377944IKZF3chr1737922746-1809599821302406
ENST00000518901ENDOVchr1778403631+ENST00000377945IKZF3chr1737922746-1809599821302406
ENST00000518901ENDOVchr1778403631+ENST00000377952IKZF3chr1737922746-1809599821302406
ENST00000518901ENDOVchr1778403631+ENST00000377958IKZF3chr1737922746-1809599821302406
ENST00000517295ENDOVchr1778403631+ENST00000346872IKZF3chr1737922746-2345796571499480
ENST00000517295ENDOVchr1778403631+ENST00000394189IKZF3chr1737922746-2006796571499480
ENST00000517295ENDOVchr1778403631+ENST00000439167IKZF3chr1737922746-2006796571499480
ENST00000517295ENDOVchr1778403631+ENST00000535189IKZF3chr1737922746-2006796571499480
ENST00000517295ENDOVchr1778403631+ENST00000377944IKZF3chr1737922746-2006796571499480
ENST00000517295ENDOVchr1778403631+ENST00000377945IKZF3chr1737922746-2006796571499480
ENST00000517295ENDOVchr1778403631+ENST00000377952IKZF3chr1737922746-2006796571499480
ENST00000517295ENDOVchr1778403631+ENST00000377958IKZF3chr1737922746-2006796571499480

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000520367ENST00000346872ENDOVchr1778403631+IKZF3chr1737922746-0.00477360.9952264
ENST00000520367ENST00000394189ENDOVchr1778403631+IKZF3chr1737922746-0.0060741530.99392587
ENST00000520367ENST00000439167ENDOVchr1778403631+IKZF3chr1737922746-0.0060741530.99392587
ENST00000520367ENST00000535189ENDOVchr1778403631+IKZF3chr1737922746-0.0060741530.99392587
ENST00000520367ENST00000377944ENDOVchr1778403631+IKZF3chr1737922746-0.0060741530.99392587
ENST00000520367ENST00000377945ENDOVchr1778403631+IKZF3chr1737922746-0.0060741530.99392587
ENST00000520367ENST00000377952ENDOVchr1778403631+IKZF3chr1737922746-0.0060741530.99392587
ENST00000520367ENST00000377958ENDOVchr1778403631+IKZF3chr1737922746-0.0060741530.99392587
ENST00000518137ENST00000346872ENDOVchr1778403631+IKZF3chr1737922746-0.0076685520.9923314
ENST00000518137ENST00000394189ENDOVchr1778403631+IKZF3chr1737922746-0.0096948350.9903052
ENST00000518137ENST00000439167ENDOVchr1778403631+IKZF3chr1737922746-0.0096948350.9903052
ENST00000518137ENST00000535189ENDOVchr1778403631+IKZF3chr1737922746-0.0096948350.9903052
ENST00000518137ENST00000377944ENDOVchr1778403631+IKZF3chr1737922746-0.0096948350.9903052
ENST00000518137ENST00000377945ENDOVchr1778403631+IKZF3chr1737922746-0.0096948350.9903052
ENST00000518137ENST00000377952ENDOVchr1778403631+IKZF3chr1737922746-0.0096948350.9903052
ENST00000518137ENST00000377958ENDOVchr1778403631+IKZF3chr1737922746-0.0096948350.9903052
ENST00000323854ENST00000346243ENDOVchr1778403631+IKZF3chr1737922746-0.0033902570.99660975
ENST00000323854ENST00000350532ENDOVchr1778403631+IKZF3chr1737922746-0.0033902570.99660975
ENST00000323854ENST00000351680ENDOVchr1778403631+IKZF3chr1737922746-0.0033902570.99660975
ENST00000323854ENST00000467757ENDOVchr1778403631+IKZF3chr1737922746-0.0033902570.99660975
ENST00000522751ENST00000439016ENDOVchr1778403631+IKZF3chr1737922746-0.0100842690.9899157
ENST00000522751ENST00000583368ENDOVchr1778403631+IKZF3chr1737922746-0.00905410.99094594
ENST00000517795ENST00000346872ENDOVchr1778403631+IKZF3chr1737922746-0.0045967780.9954032
ENST00000517795ENST00000394189ENDOVchr1778403631+IKZF3chr1737922746-0.0057855020.9942145
ENST00000517795ENST00000439167ENDOVchr1778403631+IKZF3chr1737922746-0.0057855020.9942145
ENST00000517795ENST00000535189ENDOVchr1778403631+IKZF3chr1737922746-0.0057855020.9942145
ENST00000517795ENST00000377944ENDOVchr1778403631+IKZF3chr1737922746-0.0057855020.9942145
ENST00000517795ENST00000377945ENDOVchr1778403631+IKZF3chr1737922746-0.0057855020.9942145
ENST00000517795ENST00000377952ENDOVchr1778403631+IKZF3chr1737922746-0.0057855020.9942145
ENST00000517795ENST00000377958ENDOVchr1778403631+IKZF3chr1737922746-0.0057855020.9942145
ENST00000518901ENST00000346872ENDOVchr1778403631+IKZF3chr1737922746-0.0042821750.9957178
ENST00000518901ENST00000394189ENDOVchr1778403631+IKZF3chr1737922746-0.0052006990.99479926
ENST00000518901ENST00000439167ENDOVchr1778403631+IKZF3chr1737922746-0.0052006990.99479926
ENST00000518901ENST00000535189ENDOVchr1778403631+IKZF3chr1737922746-0.0052006990.99479926
ENST00000518901ENST00000377944ENDOVchr1778403631+IKZF3chr1737922746-0.0052006990.99479926
ENST00000518901ENST00000377945ENDOVchr1778403631+IKZF3chr1737922746-0.0052006990.99479926
ENST00000518901ENST00000377952ENDOVchr1778403631+IKZF3chr1737922746-0.0052006990.99479926
ENST00000518901ENST00000377958ENDOVchr1778403631+IKZF3chr1737922746-0.0052006990.99479926
ENST00000517295ENST00000346872ENDOVchr1778403631+IKZF3chr1737922746-0.0098185990.9901814
ENST00000517295ENST00000394189ENDOVchr1778403631+IKZF3chr1737922746-0.0128355670.9871644
ENST00000517295ENST00000439167ENDOVchr1778403631+IKZF3chr1737922746-0.0128355670.9871644
ENST00000517295ENST00000535189ENDOVchr1778403631+IKZF3chr1737922746-0.0128355670.9871644
ENST00000517295ENST00000377944ENDOVchr1778403631+IKZF3chr1737922746-0.0128355670.9871644
ENST00000517295ENST00000377945ENDOVchr1778403631+IKZF3chr1737922746-0.0128355670.9871644
ENST00000517295ENST00000377952ENDOVchr1778403631+IKZF3chr1737922746-0.0128355670.9871644
ENST00000517295ENST00000377958ENDOVchr1778403631+IKZF3chr1737922746-0.0128355670.9871644

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Fusion Amino Acid Sequences


check button For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

>26558_26558_1_ENDOV-IKZF3_ENDOV_chr17_78403631_ENST00000323854_IKZF3_chr17_37922746_ENST00000346243_length(amino acids)=273AA_BP=39
MRRFPGADEGDSELQPARPLQPVLCPPLSIDGTCLLFFSEKRHCFDVNYNSSYMYEKESELIQTRMMDQAINNAISYLGAEALRPLVQTP
PAPTSEMVPVISSMYPIALTRAEMSNGAPQELEKKSIHLPEKSVPSERGLSPNNSGHDSTDTDSNHEERQNHIYQQNHMVLSRARNGMPL
LKEVPRSYELLKPPPICPRDSVKVINKEGEVMDVYRCDHCRVLFLDYVMFTIHMGCHGFRDPFECNMCGYRSHDRYEFSSHIARGEHRAL

--------------------------------------------------------------

>26558_26558_2_ENDOV-IKZF3_ENDOV_chr17_78403631_ENST00000323854_IKZF3_chr17_37922746_ENST00000350532_length(amino acids)=273AA_BP=39
MRRFPGADEGDSELQPARPLQPVLCPPLSIDGTCLLFFSEKRHCFDVNYNSSYMYEKESELIQTRMMDQAINNAISYLGAEALRPLVQTP
PAPTSEMVPVISSMYPIALTRAEMSNGAPQELEKKSIHLPEKSVPSERGLSPNNSGHDSTDTDSNHEERQNHIYQQNHMVLSRARNGMPL
LKEVPRSYELLKPPPICPRDSVKVINKEGEVMDVYRCDHCRVLFLDYVMFTIHMGCHGFRDPFECNMCGYRSHDRYEFSSHIARGEHRAL

--------------------------------------------------------------

>26558_26558_3_ENDOV-IKZF3_ENDOV_chr17_78403631_ENST00000323854_IKZF3_chr17_37922746_ENST00000351680_length(amino acids)=273AA_BP=39
MRRFPGADEGDSELQPARPLQPVLCPPLSIDGTCLLFFSEKRHCFDVNYNSSYMYEKESELIQTRMMDQAINNAISYLGAEALRPLVQTP
PAPTSEMVPVISSMYPIALTRAEMSNGAPQELEKKSIHLPEKSVPSERGLSPNNSGHDSTDTDSNHEERQNHIYQQNHMVLSRARNGMPL
LKEVPRSYELLKPPPICPRDSVKVINKEGEVMDVYRCDHCRVLFLDYVMFTIHMGCHGFRDPFECNMCGYRSHDRYEFSSHIARGEHRAL

--------------------------------------------------------------

>26558_26558_4_ENDOV-IKZF3_ENDOV_chr17_78403631_ENST00000323854_IKZF3_chr17_37922746_ENST00000467757_length(amino acids)=273AA_BP=39
MRRFPGADEGDSELQPARPLQPVLCPPLSIDGTCLLFFSEKRHCFDVNYNSSYMYEKESELIQTRMMDQAINNAISYLGAEALRPLVQTP
PAPTSEMVPVISSMYPIALTRAEMSNGAPQELEKKSIHLPEKSVPSERGLSPNNSGHDSTDTDSNHEERQNHIYQQNHMVLSRARNGMPL
LKEVPRSYELLKPPPICPRDSVKVINKEGEVMDVYRCDHCRVLFLDYVMFTIHMGCHGFRDPFECNMCGYRSHDRYEFSSHIARGEHRAL

--------------------------------------------------------------

>26558_26558_5_ENDOV-IKZF3_ENDOV_chr17_78403631_ENST00000517295_IKZF3_chr17_37922746_ENST00000346872_length(amino acids)=480AA_BP=246
MQRVGGVDVSFVKGDSVRACASLVVLSFPELEVVYEESRMVSLTAPYVSGFLAFREVPFLLELVQQLREKEPGLMPQVLLVDGNGVLHHR
GFGVACHLGVLTDLPCVGVAKKLLQVDGLENNALHKEKIRLLQTRGDSFPLLGDSGTVLGMPTGQPSPSLSQALRSHDRSTRPLYISVGH
RMSLEAAVRLTCCCCRFRIPEPVRQADICSREHIRKSLGLPGPPTPRSPKAQRPVACPKGDSGESSGEKRHCFDVNYNSSYMYEKESELI
QTRMMDQAINNAISYLGAEALRPLVQTPPAPTSEMVPVISSMYPIALTRAEMSNGAPQELEKKSIHLPEKSVPSERGLSPNNSGHDSTDT
DSNHEERQNHIYQQNHMVLSRARNGMPLLKEVPRSYELLKPPPICPRDSVKVINKEGEVMDVYRCDHCRVLFLDYVMFTIHMGCHGFRDP

--------------------------------------------------------------

>26558_26558_6_ENDOV-IKZF3_ENDOV_chr17_78403631_ENST00000517295_IKZF3_chr17_37922746_ENST00000377944_length(amino acids)=480AA_BP=246
MQRVGGVDVSFVKGDSVRACASLVVLSFPELEVVYEESRMVSLTAPYVSGFLAFREVPFLLELVQQLREKEPGLMPQVLLVDGNGVLHHR
GFGVACHLGVLTDLPCVGVAKKLLQVDGLENNALHKEKIRLLQTRGDSFPLLGDSGTVLGMPTGQPSPSLSQALRSHDRSTRPLYISVGH
RMSLEAAVRLTCCCCRFRIPEPVRQADICSREHIRKSLGLPGPPTPRSPKAQRPVACPKGDSGESSGEKRHCFDVNYNSSYMYEKESELI
QTRMMDQAINNAISYLGAEALRPLVQTPPAPTSEMVPVISSMYPIALTRAEMSNGAPQELEKKSIHLPEKSVPSERGLSPNNSGHDSTDT
DSNHEERQNHIYQQNHMVLSRARNGMPLLKEVPRSYELLKPPPICPRDSVKVINKEGEVMDVYRCDHCRVLFLDYVMFTIHMGCHGFRDP

--------------------------------------------------------------

>26558_26558_7_ENDOV-IKZF3_ENDOV_chr17_78403631_ENST00000517295_IKZF3_chr17_37922746_ENST00000377945_length(amino acids)=480AA_BP=246
MQRVGGVDVSFVKGDSVRACASLVVLSFPELEVVYEESRMVSLTAPYVSGFLAFREVPFLLELVQQLREKEPGLMPQVLLVDGNGVLHHR
GFGVACHLGVLTDLPCVGVAKKLLQVDGLENNALHKEKIRLLQTRGDSFPLLGDSGTVLGMPTGQPSPSLSQALRSHDRSTRPLYISVGH
RMSLEAAVRLTCCCCRFRIPEPVRQADICSREHIRKSLGLPGPPTPRSPKAQRPVACPKGDSGESSGEKRHCFDVNYNSSYMYEKESELI
QTRMMDQAINNAISYLGAEALRPLVQTPPAPTSEMVPVISSMYPIALTRAEMSNGAPQELEKKSIHLPEKSVPSERGLSPNNSGHDSTDT
DSNHEERQNHIYQQNHMVLSRARNGMPLLKEVPRSYELLKPPPICPRDSVKVINKEGEVMDVYRCDHCRVLFLDYVMFTIHMGCHGFRDP

--------------------------------------------------------------

>26558_26558_8_ENDOV-IKZF3_ENDOV_chr17_78403631_ENST00000517295_IKZF3_chr17_37922746_ENST00000377952_length(amino acids)=480AA_BP=246
MQRVGGVDVSFVKGDSVRACASLVVLSFPELEVVYEESRMVSLTAPYVSGFLAFREVPFLLELVQQLREKEPGLMPQVLLVDGNGVLHHR
GFGVACHLGVLTDLPCVGVAKKLLQVDGLENNALHKEKIRLLQTRGDSFPLLGDSGTVLGMPTGQPSPSLSQALRSHDRSTRPLYISVGH
RMSLEAAVRLTCCCCRFRIPEPVRQADICSREHIRKSLGLPGPPTPRSPKAQRPVACPKGDSGESSGEKRHCFDVNYNSSYMYEKESELI
QTRMMDQAINNAISYLGAEALRPLVQTPPAPTSEMVPVISSMYPIALTRAEMSNGAPQELEKKSIHLPEKSVPSERGLSPNNSGHDSTDT
DSNHEERQNHIYQQNHMVLSRARNGMPLLKEVPRSYELLKPPPICPRDSVKVINKEGEVMDVYRCDHCRVLFLDYVMFTIHMGCHGFRDP

--------------------------------------------------------------

>26558_26558_9_ENDOV-IKZF3_ENDOV_chr17_78403631_ENST00000517295_IKZF3_chr17_37922746_ENST00000377958_length(amino acids)=480AA_BP=246
MQRVGGVDVSFVKGDSVRACASLVVLSFPELEVVYEESRMVSLTAPYVSGFLAFREVPFLLELVQQLREKEPGLMPQVLLVDGNGVLHHR
GFGVACHLGVLTDLPCVGVAKKLLQVDGLENNALHKEKIRLLQTRGDSFPLLGDSGTVLGMPTGQPSPSLSQALRSHDRSTRPLYISVGH
RMSLEAAVRLTCCCCRFRIPEPVRQADICSREHIRKSLGLPGPPTPRSPKAQRPVACPKGDSGESSGEKRHCFDVNYNSSYMYEKESELI
QTRMMDQAINNAISYLGAEALRPLVQTPPAPTSEMVPVISSMYPIALTRAEMSNGAPQELEKKSIHLPEKSVPSERGLSPNNSGHDSTDT
DSNHEERQNHIYQQNHMVLSRARNGMPLLKEVPRSYELLKPPPICPRDSVKVINKEGEVMDVYRCDHCRVLFLDYVMFTIHMGCHGFRDP

--------------------------------------------------------------

>26558_26558_10_ENDOV-IKZF3_ENDOV_chr17_78403631_ENST00000517295_IKZF3_chr17_37922746_ENST00000394189_length(amino acids)=480AA_BP=246
MQRVGGVDVSFVKGDSVRACASLVVLSFPELEVVYEESRMVSLTAPYVSGFLAFREVPFLLELVQQLREKEPGLMPQVLLVDGNGVLHHR
GFGVACHLGVLTDLPCVGVAKKLLQVDGLENNALHKEKIRLLQTRGDSFPLLGDSGTVLGMPTGQPSPSLSQALRSHDRSTRPLYISVGH
RMSLEAAVRLTCCCCRFRIPEPVRQADICSREHIRKSLGLPGPPTPRSPKAQRPVACPKGDSGESSGEKRHCFDVNYNSSYMYEKESELI
QTRMMDQAINNAISYLGAEALRPLVQTPPAPTSEMVPVISSMYPIALTRAEMSNGAPQELEKKSIHLPEKSVPSERGLSPNNSGHDSTDT
DSNHEERQNHIYQQNHMVLSRARNGMPLLKEVPRSYELLKPPPICPRDSVKVINKEGEVMDVYRCDHCRVLFLDYVMFTIHMGCHGFRDP

--------------------------------------------------------------

>26558_26558_11_ENDOV-IKZF3_ENDOV_chr17_78403631_ENST00000517295_IKZF3_chr17_37922746_ENST00000439167_length(amino acids)=480AA_BP=246
MQRVGGVDVSFVKGDSVRACASLVVLSFPELEVVYEESRMVSLTAPYVSGFLAFREVPFLLELVQQLREKEPGLMPQVLLVDGNGVLHHR
GFGVACHLGVLTDLPCVGVAKKLLQVDGLENNALHKEKIRLLQTRGDSFPLLGDSGTVLGMPTGQPSPSLSQALRSHDRSTRPLYISVGH
RMSLEAAVRLTCCCCRFRIPEPVRQADICSREHIRKSLGLPGPPTPRSPKAQRPVACPKGDSGESSGEKRHCFDVNYNSSYMYEKESELI
QTRMMDQAINNAISYLGAEALRPLVQTPPAPTSEMVPVISSMYPIALTRAEMSNGAPQELEKKSIHLPEKSVPSERGLSPNNSGHDSTDT
DSNHEERQNHIYQQNHMVLSRARNGMPLLKEVPRSYELLKPPPICPRDSVKVINKEGEVMDVYRCDHCRVLFLDYVMFTIHMGCHGFRDP

--------------------------------------------------------------

>26558_26558_12_ENDOV-IKZF3_ENDOV_chr17_78403631_ENST00000517295_IKZF3_chr17_37922746_ENST00000535189_length(amino acids)=480AA_BP=246
MQRVGGVDVSFVKGDSVRACASLVVLSFPELEVVYEESRMVSLTAPYVSGFLAFREVPFLLELVQQLREKEPGLMPQVLLVDGNGVLHHR
GFGVACHLGVLTDLPCVGVAKKLLQVDGLENNALHKEKIRLLQTRGDSFPLLGDSGTVLGMPTGQPSPSLSQALRSHDRSTRPLYISVGH
RMSLEAAVRLTCCCCRFRIPEPVRQADICSREHIRKSLGLPGPPTPRSPKAQRPVACPKGDSGESSGEKRHCFDVNYNSSYMYEKESELI
QTRMMDQAINNAISYLGAEALRPLVQTPPAPTSEMVPVISSMYPIALTRAEMSNGAPQELEKKSIHLPEKSVPSERGLSPNNSGHDSTDT
DSNHEERQNHIYQQNHMVLSRARNGMPLLKEVPRSYELLKPPPICPRDSVKVINKEGEVMDVYRCDHCRVLFLDYVMFTIHMGCHGFRDP

--------------------------------------------------------------

>26558_26558_13_ENDOV-IKZF3_ENDOV_chr17_78403631_ENST00000517795_IKZF3_chr17_37922746_ENST00000346872_length(amino acids)=366AA_BP=132
MPCVGVAKKLLQVDGLENNALHKEKIRLLQTRGDSFPLLGDSGTVLGMALRSHDRSTRPLYISVGHRMSLEAAVRLTCCCCRFRIPEPVR
QADICSREHIRKSLGLPGPPTPRSPKAQRPVACPKGDSGESSGEKRHCFDVNYNSSYMYEKESELIQTRMMDQAINNAISYLGAEALRPL
VQTPPAPTSEMVPVISSMYPIALTRAEMSNGAPQELEKKSIHLPEKSVPSERGLSPNNSGHDSTDTDSNHEERQNHIYQQNHMVLSRARN
GMPLLKEVPRSYELLKPPPICPRDSVKVINKEGEVMDVYRCDHCRVLFLDYVMFTIHMGCHGFRDPFECNMCGYRSHDRYEFSSHIARGE

--------------------------------------------------------------

>26558_26558_14_ENDOV-IKZF3_ENDOV_chr17_78403631_ENST00000517795_IKZF3_chr17_37922746_ENST00000377944_length(amino acids)=366AA_BP=132
MPCVGVAKKLLQVDGLENNALHKEKIRLLQTRGDSFPLLGDSGTVLGMALRSHDRSTRPLYISVGHRMSLEAAVRLTCCCCRFRIPEPVR
QADICSREHIRKSLGLPGPPTPRSPKAQRPVACPKGDSGESSGEKRHCFDVNYNSSYMYEKESELIQTRMMDQAINNAISYLGAEALRPL
VQTPPAPTSEMVPVISSMYPIALTRAEMSNGAPQELEKKSIHLPEKSVPSERGLSPNNSGHDSTDTDSNHEERQNHIYQQNHMVLSRARN
GMPLLKEVPRSYELLKPPPICPRDSVKVINKEGEVMDVYRCDHCRVLFLDYVMFTIHMGCHGFRDPFECNMCGYRSHDRYEFSSHIARGE

--------------------------------------------------------------

>26558_26558_15_ENDOV-IKZF3_ENDOV_chr17_78403631_ENST00000517795_IKZF3_chr17_37922746_ENST00000377945_length(amino acids)=366AA_BP=132
MPCVGVAKKLLQVDGLENNALHKEKIRLLQTRGDSFPLLGDSGTVLGMALRSHDRSTRPLYISVGHRMSLEAAVRLTCCCCRFRIPEPVR
QADICSREHIRKSLGLPGPPTPRSPKAQRPVACPKGDSGESSGEKRHCFDVNYNSSYMYEKESELIQTRMMDQAINNAISYLGAEALRPL
VQTPPAPTSEMVPVISSMYPIALTRAEMSNGAPQELEKKSIHLPEKSVPSERGLSPNNSGHDSTDTDSNHEERQNHIYQQNHMVLSRARN
GMPLLKEVPRSYELLKPPPICPRDSVKVINKEGEVMDVYRCDHCRVLFLDYVMFTIHMGCHGFRDPFECNMCGYRSHDRYEFSSHIARGE

--------------------------------------------------------------

>26558_26558_16_ENDOV-IKZF3_ENDOV_chr17_78403631_ENST00000517795_IKZF3_chr17_37922746_ENST00000377952_length(amino acids)=366AA_BP=132
MPCVGVAKKLLQVDGLENNALHKEKIRLLQTRGDSFPLLGDSGTVLGMALRSHDRSTRPLYISVGHRMSLEAAVRLTCCCCRFRIPEPVR
QADICSREHIRKSLGLPGPPTPRSPKAQRPVACPKGDSGESSGEKRHCFDVNYNSSYMYEKESELIQTRMMDQAINNAISYLGAEALRPL
VQTPPAPTSEMVPVISSMYPIALTRAEMSNGAPQELEKKSIHLPEKSVPSERGLSPNNSGHDSTDTDSNHEERQNHIYQQNHMVLSRARN
GMPLLKEVPRSYELLKPPPICPRDSVKVINKEGEVMDVYRCDHCRVLFLDYVMFTIHMGCHGFRDPFECNMCGYRSHDRYEFSSHIARGE

--------------------------------------------------------------

>26558_26558_17_ENDOV-IKZF3_ENDOV_chr17_78403631_ENST00000517795_IKZF3_chr17_37922746_ENST00000377958_length(amino acids)=366AA_BP=132
MPCVGVAKKLLQVDGLENNALHKEKIRLLQTRGDSFPLLGDSGTVLGMALRSHDRSTRPLYISVGHRMSLEAAVRLTCCCCRFRIPEPVR
QADICSREHIRKSLGLPGPPTPRSPKAQRPVACPKGDSGESSGEKRHCFDVNYNSSYMYEKESELIQTRMMDQAINNAISYLGAEALRPL
VQTPPAPTSEMVPVISSMYPIALTRAEMSNGAPQELEKKSIHLPEKSVPSERGLSPNNSGHDSTDTDSNHEERQNHIYQQNHMVLSRARN
GMPLLKEVPRSYELLKPPPICPRDSVKVINKEGEVMDVYRCDHCRVLFLDYVMFTIHMGCHGFRDPFECNMCGYRSHDRYEFSSHIARGE

--------------------------------------------------------------

>26558_26558_18_ENDOV-IKZF3_ENDOV_chr17_78403631_ENST00000517795_IKZF3_chr17_37922746_ENST00000394189_length(amino acids)=366AA_BP=132
MPCVGVAKKLLQVDGLENNALHKEKIRLLQTRGDSFPLLGDSGTVLGMALRSHDRSTRPLYISVGHRMSLEAAVRLTCCCCRFRIPEPVR
QADICSREHIRKSLGLPGPPTPRSPKAQRPVACPKGDSGESSGEKRHCFDVNYNSSYMYEKESELIQTRMMDQAINNAISYLGAEALRPL
VQTPPAPTSEMVPVISSMYPIALTRAEMSNGAPQELEKKSIHLPEKSVPSERGLSPNNSGHDSTDTDSNHEERQNHIYQQNHMVLSRARN
GMPLLKEVPRSYELLKPPPICPRDSVKVINKEGEVMDVYRCDHCRVLFLDYVMFTIHMGCHGFRDPFECNMCGYRSHDRYEFSSHIARGE

--------------------------------------------------------------

>26558_26558_19_ENDOV-IKZF3_ENDOV_chr17_78403631_ENST00000517795_IKZF3_chr17_37922746_ENST00000439167_length(amino acids)=366AA_BP=132
MPCVGVAKKLLQVDGLENNALHKEKIRLLQTRGDSFPLLGDSGTVLGMALRSHDRSTRPLYISVGHRMSLEAAVRLTCCCCRFRIPEPVR
QADICSREHIRKSLGLPGPPTPRSPKAQRPVACPKGDSGESSGEKRHCFDVNYNSSYMYEKESELIQTRMMDQAINNAISYLGAEALRPL
VQTPPAPTSEMVPVISSMYPIALTRAEMSNGAPQELEKKSIHLPEKSVPSERGLSPNNSGHDSTDTDSNHEERQNHIYQQNHMVLSRARN
GMPLLKEVPRSYELLKPPPICPRDSVKVINKEGEVMDVYRCDHCRVLFLDYVMFTIHMGCHGFRDPFECNMCGYRSHDRYEFSSHIARGE

--------------------------------------------------------------

>26558_26558_20_ENDOV-IKZF3_ENDOV_chr17_78403631_ENST00000517795_IKZF3_chr17_37922746_ENST00000535189_length(amino acids)=366AA_BP=132
MPCVGVAKKLLQVDGLENNALHKEKIRLLQTRGDSFPLLGDSGTVLGMALRSHDRSTRPLYISVGHRMSLEAAVRLTCCCCRFRIPEPVR
QADICSREHIRKSLGLPGPPTPRSPKAQRPVACPKGDSGESSGEKRHCFDVNYNSSYMYEKESELIQTRMMDQAINNAISYLGAEALRPL
VQTPPAPTSEMVPVISSMYPIALTRAEMSNGAPQELEKKSIHLPEKSVPSERGLSPNNSGHDSTDTDSNHEERQNHIYQQNHMVLSRARN
GMPLLKEVPRSYELLKPPPICPRDSVKVINKEGEVMDVYRCDHCRVLFLDYVMFTIHMGCHGFRDPFECNMCGYRSHDRYEFSSHIARGE

--------------------------------------------------------------

>26558_26558_21_ENDOV-IKZF3_ENDOV_chr17_78403631_ENST00000518137_IKZF3_chr17_37922746_ENST00000346872_length(amino acids)=513AA_BP=279
MALEAAGGPPEETLSLWKREQARLKAHVVDRDTEAWQRDPAFSGLQRVGGVDVSFVKGDSVRACASLVVLSFPELEVVYEESRMVSLTAP
YVSGFLAFREVPFLLELVQQLREKEPGLMPQVLLVDGNGVLHHRGFGVACHLGVLTDLPCVGVAKKLLQVDGLENNALHKEKIRLLQTRG
DSFPLLGDSGTVLGMALRSHDRSTRPLYISVGHRMSLEAAVRLTCCCCRFRIPEPVRQADICSREHIRKSLGLPGPPTPRSPKAQRPVAC
PKGDSGESSGEKRHCFDVNYNSSYMYEKESELIQTRMMDQAINNAISYLGAEALRPLVQTPPAPTSEMVPVISSMYPIALTRAEMSNGAP
QELEKKSIHLPEKSVPSERGLSPNNSGHDSTDTDSNHEERQNHIYQQNHMVLSRARNGMPLLKEVPRSYELLKPPPICPRDSVKVINKEG

--------------------------------------------------------------

>26558_26558_22_ENDOV-IKZF3_ENDOV_chr17_78403631_ENST00000518137_IKZF3_chr17_37922746_ENST00000377944_length(amino acids)=513AA_BP=279
MALEAAGGPPEETLSLWKREQARLKAHVVDRDTEAWQRDPAFSGLQRVGGVDVSFVKGDSVRACASLVVLSFPELEVVYEESRMVSLTAP
YVSGFLAFREVPFLLELVQQLREKEPGLMPQVLLVDGNGVLHHRGFGVACHLGVLTDLPCVGVAKKLLQVDGLENNALHKEKIRLLQTRG
DSFPLLGDSGTVLGMALRSHDRSTRPLYISVGHRMSLEAAVRLTCCCCRFRIPEPVRQADICSREHIRKSLGLPGPPTPRSPKAQRPVAC
PKGDSGESSGEKRHCFDVNYNSSYMYEKESELIQTRMMDQAINNAISYLGAEALRPLVQTPPAPTSEMVPVISSMYPIALTRAEMSNGAP
QELEKKSIHLPEKSVPSERGLSPNNSGHDSTDTDSNHEERQNHIYQQNHMVLSRARNGMPLLKEVPRSYELLKPPPICPRDSVKVINKEG

--------------------------------------------------------------

>26558_26558_23_ENDOV-IKZF3_ENDOV_chr17_78403631_ENST00000518137_IKZF3_chr17_37922746_ENST00000377945_length(amino acids)=513AA_BP=279
MALEAAGGPPEETLSLWKREQARLKAHVVDRDTEAWQRDPAFSGLQRVGGVDVSFVKGDSVRACASLVVLSFPELEVVYEESRMVSLTAP
YVSGFLAFREVPFLLELVQQLREKEPGLMPQVLLVDGNGVLHHRGFGVACHLGVLTDLPCVGVAKKLLQVDGLENNALHKEKIRLLQTRG
DSFPLLGDSGTVLGMALRSHDRSTRPLYISVGHRMSLEAAVRLTCCCCRFRIPEPVRQADICSREHIRKSLGLPGPPTPRSPKAQRPVAC
PKGDSGESSGEKRHCFDVNYNSSYMYEKESELIQTRMMDQAINNAISYLGAEALRPLVQTPPAPTSEMVPVISSMYPIALTRAEMSNGAP
QELEKKSIHLPEKSVPSERGLSPNNSGHDSTDTDSNHEERQNHIYQQNHMVLSRARNGMPLLKEVPRSYELLKPPPICPRDSVKVINKEG

--------------------------------------------------------------

>26558_26558_24_ENDOV-IKZF3_ENDOV_chr17_78403631_ENST00000518137_IKZF3_chr17_37922746_ENST00000377952_length(amino acids)=513AA_BP=279
MALEAAGGPPEETLSLWKREQARLKAHVVDRDTEAWQRDPAFSGLQRVGGVDVSFVKGDSVRACASLVVLSFPELEVVYEESRMVSLTAP
YVSGFLAFREVPFLLELVQQLREKEPGLMPQVLLVDGNGVLHHRGFGVACHLGVLTDLPCVGVAKKLLQVDGLENNALHKEKIRLLQTRG
DSFPLLGDSGTVLGMALRSHDRSTRPLYISVGHRMSLEAAVRLTCCCCRFRIPEPVRQADICSREHIRKSLGLPGPPTPRSPKAQRPVAC
PKGDSGESSGEKRHCFDVNYNSSYMYEKESELIQTRMMDQAINNAISYLGAEALRPLVQTPPAPTSEMVPVISSMYPIALTRAEMSNGAP
QELEKKSIHLPEKSVPSERGLSPNNSGHDSTDTDSNHEERQNHIYQQNHMVLSRARNGMPLLKEVPRSYELLKPPPICPRDSVKVINKEG

--------------------------------------------------------------

>26558_26558_25_ENDOV-IKZF3_ENDOV_chr17_78403631_ENST00000518137_IKZF3_chr17_37922746_ENST00000377958_length(amino acids)=513AA_BP=279
MALEAAGGPPEETLSLWKREQARLKAHVVDRDTEAWQRDPAFSGLQRVGGVDVSFVKGDSVRACASLVVLSFPELEVVYEESRMVSLTAP
YVSGFLAFREVPFLLELVQQLREKEPGLMPQVLLVDGNGVLHHRGFGVACHLGVLTDLPCVGVAKKLLQVDGLENNALHKEKIRLLQTRG
DSFPLLGDSGTVLGMALRSHDRSTRPLYISVGHRMSLEAAVRLTCCCCRFRIPEPVRQADICSREHIRKSLGLPGPPTPRSPKAQRPVAC
PKGDSGESSGEKRHCFDVNYNSSYMYEKESELIQTRMMDQAINNAISYLGAEALRPLVQTPPAPTSEMVPVISSMYPIALTRAEMSNGAP
QELEKKSIHLPEKSVPSERGLSPNNSGHDSTDTDSNHEERQNHIYQQNHMVLSRARNGMPLLKEVPRSYELLKPPPICPRDSVKVINKEG

--------------------------------------------------------------

>26558_26558_26_ENDOV-IKZF3_ENDOV_chr17_78403631_ENST00000518137_IKZF3_chr17_37922746_ENST00000394189_length(amino acids)=513AA_BP=279
MALEAAGGPPEETLSLWKREQARLKAHVVDRDTEAWQRDPAFSGLQRVGGVDVSFVKGDSVRACASLVVLSFPELEVVYEESRMVSLTAP
YVSGFLAFREVPFLLELVQQLREKEPGLMPQVLLVDGNGVLHHRGFGVACHLGVLTDLPCVGVAKKLLQVDGLENNALHKEKIRLLQTRG
DSFPLLGDSGTVLGMALRSHDRSTRPLYISVGHRMSLEAAVRLTCCCCRFRIPEPVRQADICSREHIRKSLGLPGPPTPRSPKAQRPVAC
PKGDSGESSGEKRHCFDVNYNSSYMYEKESELIQTRMMDQAINNAISYLGAEALRPLVQTPPAPTSEMVPVISSMYPIALTRAEMSNGAP
QELEKKSIHLPEKSVPSERGLSPNNSGHDSTDTDSNHEERQNHIYQQNHMVLSRARNGMPLLKEVPRSYELLKPPPICPRDSVKVINKEG

--------------------------------------------------------------

>26558_26558_27_ENDOV-IKZF3_ENDOV_chr17_78403631_ENST00000518137_IKZF3_chr17_37922746_ENST00000439167_length(amino acids)=513AA_BP=279
MALEAAGGPPEETLSLWKREQARLKAHVVDRDTEAWQRDPAFSGLQRVGGVDVSFVKGDSVRACASLVVLSFPELEVVYEESRMVSLTAP
YVSGFLAFREVPFLLELVQQLREKEPGLMPQVLLVDGNGVLHHRGFGVACHLGVLTDLPCVGVAKKLLQVDGLENNALHKEKIRLLQTRG
DSFPLLGDSGTVLGMALRSHDRSTRPLYISVGHRMSLEAAVRLTCCCCRFRIPEPVRQADICSREHIRKSLGLPGPPTPRSPKAQRPVAC
PKGDSGESSGEKRHCFDVNYNSSYMYEKESELIQTRMMDQAINNAISYLGAEALRPLVQTPPAPTSEMVPVISSMYPIALTRAEMSNGAP
QELEKKSIHLPEKSVPSERGLSPNNSGHDSTDTDSNHEERQNHIYQQNHMVLSRARNGMPLLKEVPRSYELLKPPPICPRDSVKVINKEG

--------------------------------------------------------------

>26558_26558_28_ENDOV-IKZF3_ENDOV_chr17_78403631_ENST00000518137_IKZF3_chr17_37922746_ENST00000535189_length(amino acids)=513AA_BP=279
MALEAAGGPPEETLSLWKREQARLKAHVVDRDTEAWQRDPAFSGLQRVGGVDVSFVKGDSVRACASLVVLSFPELEVVYEESRMVSLTAP
YVSGFLAFREVPFLLELVQQLREKEPGLMPQVLLVDGNGVLHHRGFGVACHLGVLTDLPCVGVAKKLLQVDGLENNALHKEKIRLLQTRG
DSFPLLGDSGTVLGMALRSHDRSTRPLYISVGHRMSLEAAVRLTCCCCRFRIPEPVRQADICSREHIRKSLGLPGPPTPRSPKAQRPVAC
PKGDSGESSGEKRHCFDVNYNSSYMYEKESELIQTRMMDQAINNAISYLGAEALRPLVQTPPAPTSEMVPVISSMYPIALTRAEMSNGAP
QELEKKSIHLPEKSVPSERGLSPNNSGHDSTDTDSNHEERQNHIYQQNHMVLSRARNGMPLLKEVPRSYELLKPPPICPRDSVKVINKEG

--------------------------------------------------------------

>26558_26558_29_ENDOV-IKZF3_ENDOV_chr17_78403631_ENST00000518901_IKZF3_chr17_37922746_ENST00000346872_length(amino acids)=406AA_BP=172
MSAAAARVEEAESEVLLVDGNGVLHHRGFGVACHLGVLTDLPCVGVAKKLLQVDGLENNALHKEKIRLLQTRGDSFPLLGDSGTVLGMAL
RSHDRSTRPLYISVGHRMSLEAAVRLTCCCCRFRIPEPVRQADICSREHIRKSLGLPGPPTPRSPKAQRPVACPKGDSGESSGEKRHCFD
VNYNSSYMYEKESELIQTRMMDQAINNAISYLGAEALRPLVQTPPAPTSEMVPVISSMYPIALTRAEMSNGAPQELEKKSIHLPEKSVPS
ERGLSPNNSGHDSTDTDSNHEERQNHIYQQNHMVLSRARNGMPLLKEVPRSYELLKPPPICPRDSVKVINKEGEVMDVYRCDHCRVLFLD

--------------------------------------------------------------

>26558_26558_30_ENDOV-IKZF3_ENDOV_chr17_78403631_ENST00000518901_IKZF3_chr17_37922746_ENST00000377944_length(amino acids)=406AA_BP=172
MSAAAARVEEAESEVLLVDGNGVLHHRGFGVACHLGVLTDLPCVGVAKKLLQVDGLENNALHKEKIRLLQTRGDSFPLLGDSGTVLGMAL
RSHDRSTRPLYISVGHRMSLEAAVRLTCCCCRFRIPEPVRQADICSREHIRKSLGLPGPPTPRSPKAQRPVACPKGDSGESSGEKRHCFD
VNYNSSYMYEKESELIQTRMMDQAINNAISYLGAEALRPLVQTPPAPTSEMVPVISSMYPIALTRAEMSNGAPQELEKKSIHLPEKSVPS
ERGLSPNNSGHDSTDTDSNHEERQNHIYQQNHMVLSRARNGMPLLKEVPRSYELLKPPPICPRDSVKVINKEGEVMDVYRCDHCRVLFLD

--------------------------------------------------------------

>26558_26558_31_ENDOV-IKZF3_ENDOV_chr17_78403631_ENST00000518901_IKZF3_chr17_37922746_ENST00000377945_length(amino acids)=406AA_BP=172
MSAAAARVEEAESEVLLVDGNGVLHHRGFGVACHLGVLTDLPCVGVAKKLLQVDGLENNALHKEKIRLLQTRGDSFPLLGDSGTVLGMAL
RSHDRSTRPLYISVGHRMSLEAAVRLTCCCCRFRIPEPVRQADICSREHIRKSLGLPGPPTPRSPKAQRPVACPKGDSGESSGEKRHCFD
VNYNSSYMYEKESELIQTRMMDQAINNAISYLGAEALRPLVQTPPAPTSEMVPVISSMYPIALTRAEMSNGAPQELEKKSIHLPEKSVPS
ERGLSPNNSGHDSTDTDSNHEERQNHIYQQNHMVLSRARNGMPLLKEVPRSYELLKPPPICPRDSVKVINKEGEVMDVYRCDHCRVLFLD

--------------------------------------------------------------

>26558_26558_32_ENDOV-IKZF3_ENDOV_chr17_78403631_ENST00000518901_IKZF3_chr17_37922746_ENST00000377952_length(amino acids)=406AA_BP=172
MSAAAARVEEAESEVLLVDGNGVLHHRGFGVACHLGVLTDLPCVGVAKKLLQVDGLENNALHKEKIRLLQTRGDSFPLLGDSGTVLGMAL
RSHDRSTRPLYISVGHRMSLEAAVRLTCCCCRFRIPEPVRQADICSREHIRKSLGLPGPPTPRSPKAQRPVACPKGDSGESSGEKRHCFD
VNYNSSYMYEKESELIQTRMMDQAINNAISYLGAEALRPLVQTPPAPTSEMVPVISSMYPIALTRAEMSNGAPQELEKKSIHLPEKSVPS
ERGLSPNNSGHDSTDTDSNHEERQNHIYQQNHMVLSRARNGMPLLKEVPRSYELLKPPPICPRDSVKVINKEGEVMDVYRCDHCRVLFLD

--------------------------------------------------------------

>26558_26558_33_ENDOV-IKZF3_ENDOV_chr17_78403631_ENST00000518901_IKZF3_chr17_37922746_ENST00000377958_length(amino acids)=406AA_BP=172
MSAAAARVEEAESEVLLVDGNGVLHHRGFGVACHLGVLTDLPCVGVAKKLLQVDGLENNALHKEKIRLLQTRGDSFPLLGDSGTVLGMAL
RSHDRSTRPLYISVGHRMSLEAAVRLTCCCCRFRIPEPVRQADICSREHIRKSLGLPGPPTPRSPKAQRPVACPKGDSGESSGEKRHCFD
VNYNSSYMYEKESELIQTRMMDQAINNAISYLGAEALRPLVQTPPAPTSEMVPVISSMYPIALTRAEMSNGAPQELEKKSIHLPEKSVPS
ERGLSPNNSGHDSTDTDSNHEERQNHIYQQNHMVLSRARNGMPLLKEVPRSYELLKPPPICPRDSVKVINKEGEVMDVYRCDHCRVLFLD

--------------------------------------------------------------

>26558_26558_34_ENDOV-IKZF3_ENDOV_chr17_78403631_ENST00000518901_IKZF3_chr17_37922746_ENST00000394189_length(amino acids)=406AA_BP=172
MSAAAARVEEAESEVLLVDGNGVLHHRGFGVACHLGVLTDLPCVGVAKKLLQVDGLENNALHKEKIRLLQTRGDSFPLLGDSGTVLGMAL
RSHDRSTRPLYISVGHRMSLEAAVRLTCCCCRFRIPEPVRQADICSREHIRKSLGLPGPPTPRSPKAQRPVACPKGDSGESSGEKRHCFD
VNYNSSYMYEKESELIQTRMMDQAINNAISYLGAEALRPLVQTPPAPTSEMVPVISSMYPIALTRAEMSNGAPQELEKKSIHLPEKSVPS
ERGLSPNNSGHDSTDTDSNHEERQNHIYQQNHMVLSRARNGMPLLKEVPRSYELLKPPPICPRDSVKVINKEGEVMDVYRCDHCRVLFLD

--------------------------------------------------------------

>26558_26558_35_ENDOV-IKZF3_ENDOV_chr17_78403631_ENST00000518901_IKZF3_chr17_37922746_ENST00000439167_length(amino acids)=406AA_BP=172
MSAAAARVEEAESEVLLVDGNGVLHHRGFGVACHLGVLTDLPCVGVAKKLLQVDGLENNALHKEKIRLLQTRGDSFPLLGDSGTVLGMAL
RSHDRSTRPLYISVGHRMSLEAAVRLTCCCCRFRIPEPVRQADICSREHIRKSLGLPGPPTPRSPKAQRPVACPKGDSGESSGEKRHCFD
VNYNSSYMYEKESELIQTRMMDQAINNAISYLGAEALRPLVQTPPAPTSEMVPVISSMYPIALTRAEMSNGAPQELEKKSIHLPEKSVPS
ERGLSPNNSGHDSTDTDSNHEERQNHIYQQNHMVLSRARNGMPLLKEVPRSYELLKPPPICPRDSVKVINKEGEVMDVYRCDHCRVLFLD

--------------------------------------------------------------

>26558_26558_36_ENDOV-IKZF3_ENDOV_chr17_78403631_ENST00000518901_IKZF3_chr17_37922746_ENST00000535189_length(amino acids)=406AA_BP=172
MSAAAARVEEAESEVLLVDGNGVLHHRGFGVACHLGVLTDLPCVGVAKKLLQVDGLENNALHKEKIRLLQTRGDSFPLLGDSGTVLGMAL
RSHDRSTRPLYISVGHRMSLEAAVRLTCCCCRFRIPEPVRQADICSREHIRKSLGLPGPPTPRSPKAQRPVACPKGDSGESSGEKRHCFD
VNYNSSYMYEKESELIQTRMMDQAINNAISYLGAEALRPLVQTPPAPTSEMVPVISSMYPIALTRAEMSNGAPQELEKKSIHLPEKSVPS
ERGLSPNNSGHDSTDTDSNHEERQNHIYQQNHMVLSRARNGMPLLKEVPRSYELLKPPPICPRDSVKVINKEGEVMDVYRCDHCRVLFLD

--------------------------------------------------------------

>26558_26558_37_ENDOV-IKZF3_ENDOV_chr17_78403631_ENST00000520367_IKZF3_chr17_37922746_ENST00000346872_length(amino acids)=468AA_BP=234
MALEAAGGPPEETLSLWKREQARLKAHVVDRDTEAWQRDPAFSGLQRVGGVDVSFVKGDSVRACASLVVLSFPELEVLLVDGNGVLHHRG
FGVACHLGVLTDLPCVGVAKKLLQVDGLENNALHKEKIRLLQTRGDSFPLLGDSGTVLGMALRSHDRSTRPLYISVGHRMSLEAAVRLTC
CCCRFRIPEPVRQADICSREHIRKSLGLPGPPTPRSPKAQRPVACPKGDSGESSGEKRHCFDVNYNSSYMYEKESELIQTRMMDQAINNA
ISYLGAEALRPLVQTPPAPTSEMVPVISSMYPIALTRAEMSNGAPQELEKKSIHLPEKSVPSERGLSPNNSGHDSTDTDSNHEERQNHIY
QQNHMVLSRARNGMPLLKEVPRSYELLKPPPICPRDSVKVINKEGEVMDVYRCDHCRVLFLDYVMFTIHMGCHGFRDPFECNMCGYRSHD

--------------------------------------------------------------

>26558_26558_38_ENDOV-IKZF3_ENDOV_chr17_78403631_ENST00000520367_IKZF3_chr17_37922746_ENST00000377944_length(amino acids)=468AA_BP=234
MALEAAGGPPEETLSLWKREQARLKAHVVDRDTEAWQRDPAFSGLQRVGGVDVSFVKGDSVRACASLVVLSFPELEVLLVDGNGVLHHRG
FGVACHLGVLTDLPCVGVAKKLLQVDGLENNALHKEKIRLLQTRGDSFPLLGDSGTVLGMALRSHDRSTRPLYISVGHRMSLEAAVRLTC
CCCRFRIPEPVRQADICSREHIRKSLGLPGPPTPRSPKAQRPVACPKGDSGESSGEKRHCFDVNYNSSYMYEKESELIQTRMMDQAINNA
ISYLGAEALRPLVQTPPAPTSEMVPVISSMYPIALTRAEMSNGAPQELEKKSIHLPEKSVPSERGLSPNNSGHDSTDTDSNHEERQNHIY
QQNHMVLSRARNGMPLLKEVPRSYELLKPPPICPRDSVKVINKEGEVMDVYRCDHCRVLFLDYVMFTIHMGCHGFRDPFECNMCGYRSHD

--------------------------------------------------------------

>26558_26558_39_ENDOV-IKZF3_ENDOV_chr17_78403631_ENST00000520367_IKZF3_chr17_37922746_ENST00000377945_length(amino acids)=468AA_BP=234
MALEAAGGPPEETLSLWKREQARLKAHVVDRDTEAWQRDPAFSGLQRVGGVDVSFVKGDSVRACASLVVLSFPELEVLLVDGNGVLHHRG
FGVACHLGVLTDLPCVGVAKKLLQVDGLENNALHKEKIRLLQTRGDSFPLLGDSGTVLGMALRSHDRSTRPLYISVGHRMSLEAAVRLTC
CCCRFRIPEPVRQADICSREHIRKSLGLPGPPTPRSPKAQRPVACPKGDSGESSGEKRHCFDVNYNSSYMYEKESELIQTRMMDQAINNA
ISYLGAEALRPLVQTPPAPTSEMVPVISSMYPIALTRAEMSNGAPQELEKKSIHLPEKSVPSERGLSPNNSGHDSTDTDSNHEERQNHIY
QQNHMVLSRARNGMPLLKEVPRSYELLKPPPICPRDSVKVINKEGEVMDVYRCDHCRVLFLDYVMFTIHMGCHGFRDPFECNMCGYRSHD

--------------------------------------------------------------

>26558_26558_40_ENDOV-IKZF3_ENDOV_chr17_78403631_ENST00000520367_IKZF3_chr17_37922746_ENST00000377952_length(amino acids)=468AA_BP=234
MALEAAGGPPEETLSLWKREQARLKAHVVDRDTEAWQRDPAFSGLQRVGGVDVSFVKGDSVRACASLVVLSFPELEVLLVDGNGVLHHRG
FGVACHLGVLTDLPCVGVAKKLLQVDGLENNALHKEKIRLLQTRGDSFPLLGDSGTVLGMALRSHDRSTRPLYISVGHRMSLEAAVRLTC
CCCRFRIPEPVRQADICSREHIRKSLGLPGPPTPRSPKAQRPVACPKGDSGESSGEKRHCFDVNYNSSYMYEKESELIQTRMMDQAINNA
ISYLGAEALRPLVQTPPAPTSEMVPVISSMYPIALTRAEMSNGAPQELEKKSIHLPEKSVPSERGLSPNNSGHDSTDTDSNHEERQNHIY
QQNHMVLSRARNGMPLLKEVPRSYELLKPPPICPRDSVKVINKEGEVMDVYRCDHCRVLFLDYVMFTIHMGCHGFRDPFECNMCGYRSHD

--------------------------------------------------------------

>26558_26558_41_ENDOV-IKZF3_ENDOV_chr17_78403631_ENST00000520367_IKZF3_chr17_37922746_ENST00000377958_length(amino acids)=468AA_BP=234
MALEAAGGPPEETLSLWKREQARLKAHVVDRDTEAWQRDPAFSGLQRVGGVDVSFVKGDSVRACASLVVLSFPELEVLLVDGNGVLHHRG
FGVACHLGVLTDLPCVGVAKKLLQVDGLENNALHKEKIRLLQTRGDSFPLLGDSGTVLGMALRSHDRSTRPLYISVGHRMSLEAAVRLTC
CCCRFRIPEPVRQADICSREHIRKSLGLPGPPTPRSPKAQRPVACPKGDSGESSGEKRHCFDVNYNSSYMYEKESELIQTRMMDQAINNA
ISYLGAEALRPLVQTPPAPTSEMVPVISSMYPIALTRAEMSNGAPQELEKKSIHLPEKSVPSERGLSPNNSGHDSTDTDSNHEERQNHIY
QQNHMVLSRARNGMPLLKEVPRSYELLKPPPICPRDSVKVINKEGEVMDVYRCDHCRVLFLDYVMFTIHMGCHGFRDPFECNMCGYRSHD

--------------------------------------------------------------

>26558_26558_42_ENDOV-IKZF3_ENDOV_chr17_78403631_ENST00000520367_IKZF3_chr17_37922746_ENST00000394189_length(amino acids)=468AA_BP=234
MALEAAGGPPEETLSLWKREQARLKAHVVDRDTEAWQRDPAFSGLQRVGGVDVSFVKGDSVRACASLVVLSFPELEVLLVDGNGVLHHRG
FGVACHLGVLTDLPCVGVAKKLLQVDGLENNALHKEKIRLLQTRGDSFPLLGDSGTVLGMALRSHDRSTRPLYISVGHRMSLEAAVRLTC
CCCRFRIPEPVRQADICSREHIRKSLGLPGPPTPRSPKAQRPVACPKGDSGESSGEKRHCFDVNYNSSYMYEKESELIQTRMMDQAINNA
ISYLGAEALRPLVQTPPAPTSEMVPVISSMYPIALTRAEMSNGAPQELEKKSIHLPEKSVPSERGLSPNNSGHDSTDTDSNHEERQNHIY
QQNHMVLSRARNGMPLLKEVPRSYELLKPPPICPRDSVKVINKEGEVMDVYRCDHCRVLFLDYVMFTIHMGCHGFRDPFECNMCGYRSHD

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>26558_26558_43_ENDOV-IKZF3_ENDOV_chr17_78403631_ENST00000520367_IKZF3_chr17_37922746_ENST00000439167_length(amino acids)=468AA_BP=234
MALEAAGGPPEETLSLWKREQARLKAHVVDRDTEAWQRDPAFSGLQRVGGVDVSFVKGDSVRACASLVVLSFPELEVLLVDGNGVLHHRG
FGVACHLGVLTDLPCVGVAKKLLQVDGLENNALHKEKIRLLQTRGDSFPLLGDSGTVLGMALRSHDRSTRPLYISVGHRMSLEAAVRLTC
CCCRFRIPEPVRQADICSREHIRKSLGLPGPPTPRSPKAQRPVACPKGDSGESSGEKRHCFDVNYNSSYMYEKESELIQTRMMDQAINNA
ISYLGAEALRPLVQTPPAPTSEMVPVISSMYPIALTRAEMSNGAPQELEKKSIHLPEKSVPSERGLSPNNSGHDSTDTDSNHEERQNHIY
QQNHMVLSRARNGMPLLKEVPRSYELLKPPPICPRDSVKVINKEGEVMDVYRCDHCRVLFLDYVMFTIHMGCHGFRDPFECNMCGYRSHD

--------------------------------------------------------------

>26558_26558_44_ENDOV-IKZF3_ENDOV_chr17_78403631_ENST00000520367_IKZF3_chr17_37922746_ENST00000535189_length(amino acids)=468AA_BP=234
MALEAAGGPPEETLSLWKREQARLKAHVVDRDTEAWQRDPAFSGLQRVGGVDVSFVKGDSVRACASLVVLSFPELEVLLVDGNGVLHHRG
FGVACHLGVLTDLPCVGVAKKLLQVDGLENNALHKEKIRLLQTRGDSFPLLGDSGTVLGMALRSHDRSTRPLYISVGHRMSLEAAVRLTC
CCCRFRIPEPVRQADICSREHIRKSLGLPGPPTPRSPKAQRPVACPKGDSGESSGEKRHCFDVNYNSSYMYEKESELIQTRMMDQAINNA
ISYLGAEALRPLVQTPPAPTSEMVPVISSMYPIALTRAEMSNGAPQELEKKSIHLPEKSVPSERGLSPNNSGHDSTDTDSNHEERQNHIY
QQNHMVLSRARNGMPLLKEVPRSYELLKPPPICPRDSVKVINKEGEVMDVYRCDHCRVLFLDYVMFTIHMGCHGFRDPFECNMCGYRSHD

--------------------------------------------------------------

>26558_26558_45_ENDOV-IKZF3_ENDOV_chr17_78403631_ENST00000522751_IKZF3_chr17_37922746_ENST00000439016_length(amino acids)=270AA_BP=36
MRAHETLSRSRRRGLGAAACTTPAACALPTPFNRWSEKRHCFDVNYNSSYMYEKESELIQTRMMDQAINNAISYLGAEALRPLVQTPPAP
TSEMVPVISSMYPIALTRAEMSNGAPQELEKKSIHLPEKSVPSERGLSPNNSGHDSTDTDSNHEERQNHIYQQNHMVLSRARNGMPLLKE
VPRSYELLKPPPICPRDSVKVINKEGEVMDVYRCDHCRVLFLDYVMFTIHMGCHGFRDPFECNMCGYRSHDRYEFSSHIARGEHRALLKX

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>26558_26558_46_ENDOV-IKZF3_ENDOV_chr17_78403631_ENST00000522751_IKZF3_chr17_37922746_ENST00000583368_length(amino acids)=269AA_BP=36
MRAHETLSRSRRRGLGAAACTTPAACALPTPFNRWSEKRHCFDVNYNSSYMYEKESELIQTRMMDQAINNAISYLGAEALRPLVQTPPAP
TSEMVPVISSMYPIALTRAEMSNGAPQELEKKSIHLPEKSVPSERGLSPNNSGHDSTDTDSNHEERQNHIYQQNHMVLSRARNGMPLLKE

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Fusion Protein Functional Features


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr17:78403631/chr17:37922746)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ENDOV

Q8N8Q3

IKZF3

Q9UKT9

FUNCTION: [Isoform 1]: Endoribonuclease that specifically cleaves inosine-containing RNAs: cleaves RNA at the second phosphodiester bond 3' to inosine (PubMed:23912683, PubMed:23912718, PubMed:27573237, PubMed:31703097, PubMed:25195743). Active against both single-stranded and double-stranded RNAs (PubMed:31703097, PubMed:25195743). Has strong preference for single-stranded RNAs (ssRNAs) toward double-stranded RNAs (dsRNAs) (PubMed:23912718). Cleaves mRNAs and tRNAs containing inosine (PubMed:23912683, PubMed:31703097). Also able to cleave structure-specific dsRNA substrates containing the specific sites 5'-IIUI-3' and 5'-UIUU-3' (PubMed:23912718, PubMed:27573237). Inosine is present in a number of RNAs following editing; the function of inosine-specific endoribonuclease is still unclear: it could either play a regulatory role in edited RNAs, or be involved in antiviral response by removing the hyperedited long viral dsRNA genome that has undergone A-to-I editing (Probable). Binds branched DNA structures (PubMed:23139746). {ECO:0000269|PubMed:23139746, ECO:0000269|PubMed:23912683, ECO:0000269|PubMed:23912718, ECO:0000269|PubMed:25195743, ECO:0000269|PubMed:27573237, ECO:0000269|PubMed:31703097, ECO:0000305}.; FUNCTION: [Isoform 6]: Endoribonuclease that specifically cleaves inosine-containing RNAs: cleaves RNA at the second phosphodiester bond 3' to inosine (PubMed:31703097). Active against both single-stranded and double-stranded RNAs (PubMed:31703097). Cleaves tRNAs containing inosine (PubMed:31703097). {ECO:0000269|PubMed:31703097}.; FUNCTION: [Isoform 7]: Endoribonuclease that specifically cleaves inosine-containing RNAs: cleaves RNA at the second phosphodiester bond 3' to inosine (PubMed:31703097). Active against both single-stranded and double-stranded RNAs (PubMed:31703097). Cleaves tRNAs containing inosine (PubMed:31703097). {ECO:0000269|PubMed:31703097}.FUNCTION: Transcription factor that plays an important role in the regulation of lymphocyte differentiation. Plays an essential role in regulation of B-cell differentiation, proliferation and maturation to an effector state. Involved in regulating BCL2 expression and controlling apoptosis in T-cells in an IL2-dependent manner. {ECO:0000269|PubMed:10369681}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

* Minus value of BPloci means that the break pointn is located before the CDS.
- Retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneENDOVchr17:78403631chr17:37922746ENST00000518137+910225_228279.3333333333333283.0Compositional biasNote=Poly-Cys
HgeneENDOVchr17:78403631chr17:37922746ENST00000520367+89225_228234.33333333333334238.0Compositional biasNote=Poly-Cys
TgeneIKZF3chr17:78403631chr17:37922746ENST0000034624346202_224197.33333333333334432.0Zinc fingerC2H2-type 4%3B atypical
TgeneIKZF3chr17:78403631chr17:37922746ENST0000034624346452_474197.33333333333334432.0Zinc fingerC2H2-type 5
TgeneIKZF3chr17:78403631chr17:37922746ENST0000034624346480_504197.33333333333334432.0Zinc fingerC2H2-type 6%3B atypical
TgeneIKZF3chr17:78403631chr17:37922746ENST0000034687268452_474275.3333333333333510.0Zinc fingerC2H2-type 5
TgeneIKZF3chr17:78403631chr17:37922746ENST0000034687268480_504275.3333333333333510.0Zinc fingerC2H2-type 6%3B atypical
TgeneIKZF3chr17:78403631chr17:37922746ENST0000035053257452_474236.33333333333334471.0Zinc fingerC2H2-type 5
TgeneIKZF3chr17:78403631chr17:37922746ENST0000035053257480_504236.33333333333334471.0Zinc fingerC2H2-type 6%3B atypical
TgeneIKZF3chr17:78403631chr17:37922746ENST0000035168057452_474236.33333333333334471.0Zinc fingerC2H2-type 5
TgeneIKZF3chr17:78403631chr17:37922746ENST0000035168057480_504236.33333333333334471.0Zinc fingerC2H2-type 6%3B atypical
TgeneIKZF3chr17:78403631chr17:37922746ENST0000037794446146_168132.33333333333334367.0Zinc fingerC2H2-type 2
TgeneIKZF3chr17:78403631chr17:37922746ENST0000037794446174_196132.33333333333334367.0Zinc fingerC2H2-type 3
TgeneIKZF3chr17:78403631chr17:37922746ENST0000037794446202_224132.33333333333334367.0Zinc fingerC2H2-type 4%3B atypical
TgeneIKZF3chr17:78403631chr17:37922746ENST0000037794446452_474132.33333333333334367.0Zinc fingerC2H2-type 5
TgeneIKZF3chr17:78403631chr17:37922746ENST0000037794446480_504132.33333333333334367.0Zinc fingerC2H2-type 6%3B atypical
TgeneIKZF3chr17:78403631chr17:37922746ENST0000037794535146_168141.33333333333334376.0Zinc fingerC2H2-type 2
TgeneIKZF3chr17:78403631chr17:37922746ENST0000037794535174_196141.33333333333334376.0Zinc fingerC2H2-type 3
TgeneIKZF3chr17:78403631chr17:37922746ENST0000037794535202_224141.33333333333334376.0Zinc fingerC2H2-type 4%3B atypical
TgeneIKZF3chr17:78403631chr17:37922746ENST0000037794535452_474141.33333333333334376.0Zinc fingerC2H2-type 5
TgeneIKZF3chr17:78403631chr17:37922746ENST0000037794535480_504141.33333333333334376.0Zinc fingerC2H2-type 6%3B atypical
TgeneIKZF3chr17:78403631chr17:37922746ENST0000037795224118_14054.333333333333336289.0Zinc fingerC2H2-type 1
TgeneIKZF3chr17:78403631chr17:37922746ENST0000037795224146_16854.333333333333336289.0Zinc fingerC2H2-type 2
TgeneIKZF3chr17:78403631chr17:37922746ENST0000037795224174_19654.333333333333336289.0Zinc fingerC2H2-type 3
TgeneIKZF3chr17:78403631chr17:37922746ENST0000037795224202_22454.333333333333336289.0Zinc fingerC2H2-type 4%3B atypical
TgeneIKZF3chr17:78403631chr17:37922746ENST0000037795224452_47454.333333333333336289.0Zinc fingerC2H2-type 5
TgeneIKZF3chr17:78403631chr17:37922746ENST0000037795224480_50454.333333333333336289.0Zinc fingerC2H2-type 6%3B atypical
TgeneIKZF3chr17:78403631chr17:37922746ENST0000037795857202_224188.33333333333334423.0Zinc fingerC2H2-type 4%3B atypical
TgeneIKZF3chr17:78403631chr17:37922746ENST0000037795857452_474188.33333333333334423.0Zinc fingerC2H2-type 5
TgeneIKZF3chr17:78403631chr17:37922746ENST0000037795857480_504188.33333333333334423.0Zinc fingerC2H2-type 6%3B atypical
TgeneIKZF3chr17:78403631chr17:37922746ENST0000039418935118_14093.33333333333333328.0Zinc fingerC2H2-type 1
TgeneIKZF3chr17:78403631chr17:37922746ENST0000039418935146_16893.33333333333333328.0Zinc fingerC2H2-type 2
TgeneIKZF3chr17:78403631chr17:37922746ENST0000039418935174_19693.33333333333333328.0Zinc fingerC2H2-type 3
TgeneIKZF3chr17:78403631chr17:37922746ENST0000039418935202_22493.33333333333333328.0Zinc fingerC2H2-type 4%3B atypical
TgeneIKZF3chr17:78403631chr17:37922746ENST0000039418935452_47493.33333333333333328.0Zinc fingerC2H2-type 5
TgeneIKZF3chr17:78403631chr17:37922746ENST0000039418935480_50493.33333333333333328.0Zinc fingerC2H2-type 6%3B atypical
TgeneIKZF3chr17:78403631chr17:37922746ENST0000043901646202_224180.33333333333334415.0Zinc fingerC2H2-type 4%3B atypical
TgeneIKZF3chr17:78403631chr17:37922746ENST0000043901646452_474180.33333333333334415.0Zinc fingerC2H2-type 5
TgeneIKZF3chr17:78403631chr17:37922746ENST0000043901646480_504180.33333333333334415.0Zinc fingerC2H2-type 6%3B atypical
TgeneIKZF3chr17:78403631chr17:37922746ENST0000043916746202_224202.33333333333334437.0Zinc fingerC2H2-type 4%3B atypical
TgeneIKZF3chr17:78403631chr17:37922746ENST0000043916746452_474202.33333333333334437.0Zinc fingerC2H2-type 5
TgeneIKZF3chr17:78403631chr17:37922746ENST0000043916746480_504202.33333333333334437.0Zinc fingerC2H2-type 6%3B atypical
TgeneIKZF3chr17:78403631chr17:37922746ENST0000046775757452_474219.33333333333334454.0Zinc fingerC2H2-type 5
TgeneIKZF3chr17:78403631chr17:37922746ENST0000046775757480_504219.33333333333334454.0Zinc fingerC2H2-type 6%3B atypical
TgeneIKZF3chr17:78403631chr17:37922746ENST0000053518957452_474241.33333333333334476.0Zinc fingerC2H2-type 5
TgeneIKZF3chr17:78403631chr17:37922746ENST0000053518957480_504241.33333333333334476.0Zinc fingerC2H2-type 6%3B atypical

- Not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneENDOVchr17:78403631chr17:37922746ENST00000323854+18225_2280265.0Compositional biasNote=Poly-Cys
HgeneENDOVchr17:78403631chr17:37922746ENST00000517795+67225_22885.3333333333333389.0Compositional biasNote=Poly-Cys
HgeneENDOVchr17:78403631chr17:37922746ENST00000518901+78225_22885.3333333333333389.0Compositional biasNote=Poly-Cys
HgeneENDOVchr17:78403631chr17:37922746ENST00000518907+15225_228066.0Compositional biasNote=Poly-Cys
HgeneENDOVchr17:78403631chr17:37922746ENST00000520284+16225_228066.0Compositional biasNote=Poly-Cys
TgeneIKZF3chr17:78403631chr17:37922746ENST0000034624346118_140197.33333333333334432.0Zinc fingerC2H2-type 1
TgeneIKZF3chr17:78403631chr17:37922746ENST0000034624346146_168197.33333333333334432.0Zinc fingerC2H2-type 2
TgeneIKZF3chr17:78403631chr17:37922746ENST0000034624346174_196197.33333333333334432.0Zinc fingerC2H2-type 3
TgeneIKZF3chr17:78403631chr17:37922746ENST0000034687268118_140275.3333333333333510.0Zinc fingerC2H2-type 1
TgeneIKZF3chr17:78403631chr17:37922746ENST0000034687268146_168275.3333333333333510.0Zinc fingerC2H2-type 2
TgeneIKZF3chr17:78403631chr17:37922746ENST0000034687268174_196275.3333333333333510.0Zinc fingerC2H2-type 3
TgeneIKZF3chr17:78403631chr17:37922746ENST0000034687268202_224275.3333333333333510.0Zinc fingerC2H2-type 4%3B atypical
TgeneIKZF3chr17:78403631chr17:37922746ENST0000035053257118_140236.33333333333334471.0Zinc fingerC2H2-type 1
TgeneIKZF3chr17:78403631chr17:37922746ENST0000035053257146_168236.33333333333334471.0Zinc fingerC2H2-type 2
TgeneIKZF3chr17:78403631chr17:37922746ENST0000035053257174_196236.33333333333334471.0Zinc fingerC2H2-type 3
TgeneIKZF3chr17:78403631chr17:37922746ENST0000035053257202_224236.33333333333334471.0Zinc fingerC2H2-type 4%3B atypical
TgeneIKZF3chr17:78403631chr17:37922746ENST0000035168057118_140236.33333333333334471.0Zinc fingerC2H2-type 1
TgeneIKZF3chr17:78403631chr17:37922746ENST0000035168057146_168236.33333333333334471.0Zinc fingerC2H2-type 2
TgeneIKZF3chr17:78403631chr17:37922746ENST0000035168057174_196236.33333333333334471.0Zinc fingerC2H2-type 3
TgeneIKZF3chr17:78403631chr17:37922746ENST0000035168057202_224236.33333333333334471.0Zinc fingerC2H2-type 4%3B atypical
TgeneIKZF3chr17:78403631chr17:37922746ENST0000037794446118_140132.33333333333334367.0Zinc fingerC2H2-type 1
TgeneIKZF3chr17:78403631chr17:37922746ENST0000037794535118_140141.33333333333334376.0Zinc fingerC2H2-type 1
TgeneIKZF3chr17:78403631chr17:37922746ENST0000037795857118_140188.33333333333334423.0Zinc fingerC2H2-type 1
TgeneIKZF3chr17:78403631chr17:37922746ENST0000037795857146_168188.33333333333334423.0Zinc fingerC2H2-type 2
TgeneIKZF3chr17:78403631chr17:37922746ENST0000037795857174_196188.33333333333334423.0Zinc fingerC2H2-type 3
TgeneIKZF3chr17:78403631chr17:37922746ENST0000043901646118_140180.33333333333334415.0Zinc fingerC2H2-type 1
TgeneIKZF3chr17:78403631chr17:37922746ENST0000043901646146_168180.33333333333334415.0Zinc fingerC2H2-type 2
TgeneIKZF3chr17:78403631chr17:37922746ENST0000043901646174_196180.33333333333334415.0Zinc fingerC2H2-type 3
TgeneIKZF3chr17:78403631chr17:37922746ENST0000043916746118_140202.33333333333334437.0Zinc fingerC2H2-type 1
TgeneIKZF3chr17:78403631chr17:37922746ENST0000043916746146_168202.33333333333334437.0Zinc fingerC2H2-type 2
TgeneIKZF3chr17:78403631chr17:37922746ENST0000043916746174_196202.33333333333334437.0Zinc fingerC2H2-type 3
TgeneIKZF3chr17:78403631chr17:37922746ENST0000046775757118_140219.33333333333334454.0Zinc fingerC2H2-type 1
TgeneIKZF3chr17:78403631chr17:37922746ENST0000046775757146_168219.33333333333334454.0Zinc fingerC2H2-type 2
TgeneIKZF3chr17:78403631chr17:37922746ENST0000046775757174_196219.33333333333334454.0Zinc fingerC2H2-type 3
TgeneIKZF3chr17:78403631chr17:37922746ENST0000046775757202_224219.33333333333334454.0Zinc fingerC2H2-type 4%3B atypical
TgeneIKZF3chr17:78403631chr17:37922746ENST0000053518957118_140241.33333333333334476.0Zinc fingerC2H2-type 1
TgeneIKZF3chr17:78403631chr17:37922746ENST0000053518957146_168241.33333333333334476.0Zinc fingerC2H2-type 2
TgeneIKZF3chr17:78403631chr17:37922746ENST0000053518957174_196241.33333333333334476.0Zinc fingerC2H2-type 3
TgeneIKZF3chr17:78403631chr17:37922746ENST0000053518957202_224241.33333333333334476.0Zinc fingerC2H2-type 4%3B atypical


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Fusion Protein-Protein Interaction


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type from validated records (BIOGRID-3.4.160)
GenePPI interactors


check button Protein-protein interactors based on sequence similarity (STRING)
GeneSTRING network
ENDOV
IKZF3


check button - Retained interactions in fusion protein (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost interactions due to fusion (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs to ENDOV-IKZF3


check button Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDrugSourcePMID

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Related Diseases to ENDOV-IKZF3


check button Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDiseaseSourcePMID

check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource