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Fusion Protein:AFF1-KMT2A |
Fusion Protein Summary |
 Fusion gene summary |
| Fusion partner gene information | Fusion gene name: AFF1-KMT2A | FusionPDB ID: 2660 | FusionGDB2.0 ID: 2660 | Hgene | Tgene | Gene symbol | AFF1 | KMT2A | Gene ID | 4299 | 4297 |
| Gene name | AF4/FMR2 family member 1 | lysine methyltransferase 2A | |
| Synonyms | AF4|MLLT2|PBM1 | ALL-1|CXXC7|HRX|HTRX1|MLL|MLL1|MLL1A|TRX1|WDSTS | |
| Cytomap | 4q21.3-q22.1 | 11q23.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | AF4/FMR2 family member 1ALL1-fused gene from chromosome 4 proteinmyeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 2pre-B-cell monocytic leukemia partner 1proto-oncogene AF4 | histone-lysine N-methyltransferase 2ACXXC-type zinc finger protein 7lysine (K)-specific methyltransferase 2Alysine N-methyltransferase 2Amixed lineage leukemia 1myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)trithorax-like | |
| Modification date | 20200313 | 20200319 | |
| UniProtAcc | P51825 | Q03164 | |
| Ensembl transtripts involved in fusion gene | ENST ids | ENST00000307808, ENST00000395146, ENST00000544085, ENST00000511996, | ENST00000420751, ENST00000354520, ENST00000389506, ENST00000534358, |
| Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0) | * DoF score | 27 X 51 X 13=17901 | 31 X 72 X 3=6696 |
| # samples | 68 | 79 | |
| ** MAII score | log2(68/17901*10)=-4.71836162613835 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(79/6696*10)=-3.08337496948588 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context (manual curation of fusion genes in FusionPDB) | PubMed: AFF1 [Title/Abstract] AND KMT2A [Title/Abstract] AND fusion [Title/Abstract] The MLL recombinome of acute leukemias in 2013 (pmid: 23628958) | ||
| Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0) | KMT2A(118353210)-AFF1(88005270), # samples:3 KMT2A(118355690)-AFF1(88005270), # samples:3 AFF1(87989217)-KMT2A(118358015), # samples:3 | ||
| Anticipated loss of major functional domain due to fusion event. | AFF1-KMT2A seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. AFF1-KMT2A seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. AFF1-KMT2A seems lost the major protein functional domain in Hgene partner, which is a epigenetic factor by not retaining the major functional domain in the partially deleted in-frame ORF. AFF1-KMT2A seems lost the major protein functional domain in Hgene partner, which is a epigenetic factor by not retaining the major functional domain in the partially deleted in-frame ORF. AFF1-KMT2A seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. AFF1-KMT2A seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. AFF1-KMT2A seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target by not retaining the major functional domain in the partially deleted in-frame ORF. AFF1-KMT2A seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target by not retaining the major functional domain in the partially deleted in-frame ORF. AFF1-KMT2A seems lost the major protein functional domain in Hgene partner, which is a transcription factor by not retaining the major functional domain in the partially deleted in-frame ORF. AFF1-KMT2A seems lost the major protein functional domain in Hgene partner, which is a transcription factor by not retaining the major functional domain in the partially deleted in-frame ORF. KMT2A-AFF1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. KMT2A-AFF1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. AFF1-KMT2A seems lost the major protein functional domain in Hgene partner, which is a CGC due to the frame-shifted ORF. AFF1-KMT2A seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF. AFF1-KMT2A seems lost the major protein functional domain in Tgene partner, which is a CGC due to the frame-shifted ORF. AFF1-KMT2A seems lost the major protein functional domain in Tgene partner, which is a epigenetic factor due to the frame-shifted ORF. AFF1-KMT2A seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF. AFF1-KMT2A seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF. AFF1-KMT2A seems lost the major protein functional domain in Tgene partner, which is a transcription factor due to the frame-shifted ORF. KMT2A-AFF1 seems lost the major protein functional domain in Hgene partner, which is a CGC due to the frame-shifted ORF. KMT2A-AFF1 seems lost the major protein functional domain in Hgene partner, which is a epigenetic factor due to the frame-shifted ORF. KMT2A-AFF1 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF. KMT2A-AFF1 seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF. KMT2A-AFF1 seems lost the major protein functional domain in Hgene partner, which is a transcription factor due to the frame-shifted ORF. KMT2A-AFF1 seems lost the major protein functional domain in Tgene partner, which is a CGC due to the frame-shifted ORF. KMT2A-AFF1 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | KMT2A | GO:0044648 | histone H3-K4 dimethylation | 25561738 |
| Tgene | KMT2A | GO:0045944 | positive regulation of transcription by RNA polymerase II | 20861184 |
| Tgene | KMT2A | GO:0051568 | histone H3-K4 methylation | 19556245 |
| Tgene | KMT2A | GO:0065003 | protein-containing complex assembly | 15199122 |
| Tgene | KMT2A | GO:0080182 | histone H3-K4 trimethylation | 20861184 |
| Tgene | KMT2A | GO:0097692 | histone H3-K4 monomethylation | 25561738|26324722 |
| Fusion gene breakpoints across AFF1 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across KMT2A (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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Fusion Gene Sample Information |
| Fusion gene information from FusionGDB2.0. |
| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerKB3 | . | . | AFF1 | chr4 | 87967438 | + | KMT2A | chr11 | 118352429 | |
| ChimerKB3 | . | . | AFF1 | chr4 | 87967438 | + | KMT2A | chr11 | 118354897 | |
| ChimerKB3 | . | . | AFF1 | chr4 | 87967438 | + | KMT2A | chr11 | 118359328 | |
| ChimerKB3 | . | . | AFF1 | chr4 | 87968746 | + | KMT2A | chr11 | 118354897 | |
| ChimerKB3 | . | . | AFF1 | chr4 | 87983594 | + | KMT2A | chr11 | 118359329 | + |
| ChimerKB3 | . | . | AFF1 | chr4 | 87999280 | + | KMT2A | chr11 | 118359329 | + |
| ChimerKB3 | . | . | AFF1 | chr4 | 88024832 | + | KMT2A | chr11 | 118355577 | + |
| ChiTaRS5.0 | N/A | AF029700 | AFF1 | chr4 | 87969803 | + | KMT2A | chr11 | 118355453 | + |
| ChiTaRS5.0 | N/A | AF177235 | AFF1 | chr4 | 88007918 | + | KMT2A | chr11 | 118353544 | + |
| ChiTaRS5.0 | N/A | AF177238 | AFF1 | chr4 | 88005317 | + | KMT2A | chr11 | 118354896 | + |
| ChiTaRS5.0 | N/A | AF177239 | AFF1 | chr4 | 88005317 | + | KMT2A | chr11 | 118354896 | + |
| ChiTaRS5.0 | N/A | AF397907 | AFF1 | chr4 | 87976145 | + | KMT2A | chr11 | 118354704 | + |
| ChiTaRS5.0 | N/A | AF487904 | AFF1 | chr4 | 88027361 | + | KMT2A | chr11 | 118359135 | + |
| ChiTaRS5.0 | N/A | AF487906 | AFF1 | chr4 | 87968752 | + | KMT2A | chr11 | 118359327 | + |
| ChiTaRS5.0 | N/A | AF492831 | AFF1 | chr4 | 87968752 | + | KMT2A | chr11 | 118359327 | + |
| ChiTaRS5.0 | N/A | AJ235378 | AFF1 | chr4 | 88012878 | + | KMT2A | chr11 | 118356078 | + |
| ChiTaRS5.0 | N/A | AJ408906 | AFF1 | chr4 | 88006441 | + | KMT2A | chr11 | 118358920 | + |
| ChiTaRS5.0 | N/A | AJ408916 | AFF1 | chr4 | 87998593 | + | KMT2A | chr11 | 118358993 | + |
| ChiTaRS5.0 | N/A | AJ408921 | AFF1 | chr4 | 88011400 | + | KMT2A | chr11 | 118355431 | + |
| ChiTaRS5.0 | N/A | AJ408936 | AFF1 | chr4 | 88010904 | + | KMT2A | chr11 | 118355645 | + |
| ChiTaRS5.0 | N/A | AJ408938 | AFF1 | chr4 | 87999616 | + | KMT2A | chr11 | 118353433 | + |
| ChiTaRS5.0 | N/A | AJ408946 | AFF1 | chr4 | 87969550 | + | KMT2A | chr11 | 118354832 | + |
| ChiTaRS5.0 | N/A | AJ408950 | AFF1 | chr4 | 87979861 | + | KMT2A | chr11 | 118355304 | + |
| ChiTaRS5.0 | N/A | AJ408952 | AFF1 | chr4 | 87994386 | + | KMT2A | chr11 | 118355735 | + |
| ChiTaRS5.0 | N/A | AJ430602 | AFF1 | chr4 | 88011390 | + | KMT2A | chr11 | 118358244 | + |
| ChiTaRS5.0 | N/A | AJ430604 | AFF1 | chr4 | 88011400 | + | KMT2A | chr11 | 118355431 | + |
| ChiTaRS5.0 | N/A | AJ430605 | AFF1 | chr4 | 87989217 | + | KMT2A | chr11 | 118358015 | + |
| ChiTaRS5.0 | N/A | AM050751 | AFF1 | chr4 | 87942823 | + | KMT2A | chr11 | 118354813 | + |
| ChiTaRS5.0 | N/A | AM050777 | AFF1 | chr4 | 88011965 | + | KMT2A | chr11 | 118355475 | + |
| ChiTaRS5.0 | N/A | AM949752 | AFF1 | chr4 | 88038023 | + | KMT2A | chr11 | 118359133 | + |
| ChiTaRS5.0 | N/A | AM949753 | AFF1 | chr4 | 87999280 | + | KMT2A | chr11 | 118359005 | + |
| ChiTaRS5.0 | N/A | AY288760 | AFF1 | chr4 | 87989217 | + | KMT2A | chr11 | 118358015 | + |
| ChiTaRS5.0 | N/A | AY288767 | AFF1 | chr4 | 88012888 | + | KMT2A | chr11 | 118357698 | + |
| ChiTaRS5.0 | N/A | AY288769 | AFF1 | chr4 | 87969718 | + | KMT2A | chr11 | 118355457 | + |
| ChiTaRS5.0 | N/A | AY288771 | AFF1 | chr4 | 87989217 | + | KMT2A | chr11 | 118358015 | + |
| ChiTaRS5.0 | N/A | DQ284496 | AFF1 | chr4 | 87998498 | + | KMT2A | chr11 | 118357815 | + |
| ChiTaRS5.0 | N/A | DQ284497 | AFF1 | chr4 | 87998784 | + | KMT2A | chr11 | 118355983 | + |
| ChiTaRS5.0 | N/A | DQ284498 | AFF1 | chr4 | 87994881 | + | KMT2A | chr11 | 118358290 | + |
| ChiTaRS5.0 | N/A | KT444627 | AFF1 | chr4 | 88027391 | + | KMT2A | chr11 | 118353636 | + |
| ChiTaRS5.0 | N/A | KT444631 | AFF1 | chr4 | 87968747 | + | KMT2A | chr11 | 118354896 | + |
| ChiTaRS5.0 | N/A | KT444632 | AFF1 | chr4 | 87968747 | + | KMT2A | chr11 | 118354896 | + |
| ChiTaRS5.0 | N/A | S48045 | AFF1 | chr4 | 88001854 | - | KMT2A | chr11 | 118355075 | - |
| ChiTaRS5.0 | N/A | X83605 | AFF1 | chr4 | 87997872 | + | KMT2A | chr11 | 118355317 | + |
| ChiTaRS5.0 | N/A | Y16605 | AFF1 | chr4 | 88001845 | + | KMT2A | chr11 | 118354619 | + |
| ChiTaRS5.0 | N/A | Y16608 | AFF1 | chr4 | 87997872 | + | KMT2A | chr11 | 118355317 | + |
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Fusion ORF Analysis |
| Fusion information from ORFfinder translation from full-length transcript sequence from FusionPDB. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000395146 | AFF1 | chr4 | 87967438 | + | ENST00000534358 | KMT2A | chr11 | 118354897 | 12919 | 434 | 266 | 8266 | 2666 | |
| ENST00000395146 | AFF1 | chr4 | 87967438 | + | ENST00000389506 | KMT2A | chr11 | 118354897 | 10003 | 434 | 266 | 8257 | 2663 | |
| ENST00000395146 | AFF1 | chr4 | 87967438 | + | ENST00000354520 | KMT2A | chr11 | 118354897 | 10668 | 434 | 266 | 8143 | 2625 | |
| ENST00000307808 | AFF1 | chr4 | 87967438 | + | ENST00000534358 | KMT2A | chr11 | 118354897 | 13043 | 558 | 420 | 8390 | 2656 | |
| ENST00000307808 | AFF1 | chr4 | 87967438 | + | ENST00000389506 | KMT2A | chr11 | 118354897 | 10127 | 558 | 420 | 8381 | 2653 | |
| ENST00000307808 | AFF1 | chr4 | 87967438 | + | ENST00000354520 | KMT2A | chr11 | 118354897 | 10792 | 558 | 420 | 8267 | 2615 | |
| ENST00000395146 | AFF1 | chr4 | 87967438 | + | ENST00000534358 | KMT2A | chr11 | 118359328 | 12673 | 434 | 266 | 8020 | 2584 | |
| ENST00000395146 | AFF1 | chr4 | 87967438 | + | ENST00000389506 | KMT2A | chr11 | 118359328 | 9757 | 434 | 266 | 8011 | 2581 | |
| ENST00000395146 | AFF1 | chr4 | 87967438 | + | ENST00000354520 | KMT2A | chr11 | 118359328 | 10536 | 434 | 266 | 8011 | 2581 | |
| ENST00000307808 | AFF1 | chr4 | 87967438 | + | ENST00000534358 | KMT2A | chr11 | 118359328 | 12797 | 558 | 420 | 8144 | 2574 | |
| ENST00000307808 | AFF1 | chr4 | 87967438 | + | ENST00000389506 | KMT2A | chr11 | 118359328 | 9881 | 558 | 420 | 8135 | 2571 | |
| ENST00000307808 | AFF1 | chr4 | 87967438 | + | ENST00000354520 | KMT2A | chr11 | 118359328 | 10660 | 558 | 420 | 8135 | 2571 | |
| ENST00000395146 | AFF1 | chr4 | 87968746 | + | ENST00000534358 | KMT2A | chr11 | 118354897 | 13819 | 1334 | 266 | 9166 | 2966 | |
| ENST00000395146 | AFF1 | chr4 | 87968746 | + | ENST00000389506 | KMT2A | chr11 | 118354897 | 10903 | 1334 | 266 | 9157 | 2963 | |
| ENST00000395146 | AFF1 | chr4 | 87968746 | + | ENST00000354520 | KMT2A | chr11 | 118354897 | 11568 | 1334 | 266 | 9043 | 2925 | |
| ENST00000307808 | AFF1 | chr4 | 87968746 | + | ENST00000534358 | KMT2A | chr11 | 118354897 | 13943 | 1458 | 420 | 9290 | 2956 | |
| ENST00000307808 | AFF1 | chr4 | 87968746 | + | ENST00000389506 | KMT2A | chr11 | 118354897 | 11027 | 1458 | 420 | 9281 | 2953 | |
| ENST00000307808 | AFF1 | chr4 | 87968746 | + | ENST00000354520 | KMT2A | chr11 | 118354897 | 11692 | 1458 | 420 | 9167 | 2915 | |
| ENST00000395146 | AFF1 | chr4 | 88005317 | + | ENST00000534358 | KMT2A | chr11 | 118354896 | + | 13864 | 1379 | 266 | 9211 | 2981 |
| ENST00000395146 | AFF1 | chr4 | 88005317 | + | ENST00000389506 | KMT2A | chr11 | 118354896 | + | 10948 | 1379 | 266 | 9202 | 2978 |
| ENST00000395146 | AFF1 | chr4 | 88005317 | + | ENST00000354520 | KMT2A | chr11 | 118354896 | + | 11613 | 1379 | 266 | 9088 | 2940 |
| ENST00000307808 | AFF1 | chr4 | 88005317 | + | ENST00000534358 | KMT2A | chr11 | 118354896 | + | 13988 | 1503 | 420 | 9335 | 2971 |
| ENST00000307808 | AFF1 | chr4 | 88005317 | + | ENST00000389506 | KMT2A | chr11 | 118354896 | + | 11072 | 1503 | 420 | 9326 | 2968 |
| ENST00000307808 | AFF1 | chr4 | 88005317 | + | ENST00000354520 | KMT2A | chr11 | 118354896 | + | 11737 | 1503 | 420 | 9212 | 2930 |
| ENST00000395146 | AFF1 | chr4 | 87968752 | + | ENST00000534358 | KMT2A | chr11 | 118359327 | + | 13573 | 1334 | 266 | 8920 | 2884 |
| ENST00000395146 | AFF1 | chr4 | 87968752 | + | ENST00000389506 | KMT2A | chr11 | 118359327 | + | 10657 | 1334 | 266 | 8911 | 2881 |
| ENST00000395146 | AFF1 | chr4 | 87968752 | + | ENST00000354520 | KMT2A | chr11 | 118359327 | + | 11436 | 1334 | 266 | 8911 | 2881 |
| ENST00000307808 | AFF1 | chr4 | 87968752 | + | ENST00000534358 | KMT2A | chr11 | 118359327 | + | 13697 | 1458 | 420 | 9044 | 2874 |
| ENST00000307808 | AFF1 | chr4 | 87968752 | + | ENST00000389506 | KMT2A | chr11 | 118359327 | + | 10781 | 1458 | 420 | 9035 | 2871 |
| ENST00000307808 | AFF1 | chr4 | 87968752 | + | ENST00000354520 | KMT2A | chr11 | 118359327 | + | 11560 | 1458 | 420 | 9035 | 2871 |
| ENST00000395146 | AFF1 | chr4 | 87968747 | + | ENST00000534358 | KMT2A | chr11 | 118354896 | + | 13819 | 1334 | 266 | 9166 | 2966 |
| ENST00000395146 | AFF1 | chr4 | 87968747 | + | ENST00000389506 | KMT2A | chr11 | 118354896 | + | 10903 | 1334 | 266 | 9157 | 2963 |
| ENST00000395146 | AFF1 | chr4 | 87968747 | + | ENST00000354520 | KMT2A | chr11 | 118354896 | + | 11568 | 1334 | 266 | 9043 | 2925 |
| ENST00000307808 | AFF1 | chr4 | 87968747 | + | ENST00000534358 | KMT2A | chr11 | 118354896 | + | 13943 | 1458 | 420 | 9290 | 2956 |
| ENST00000307808 | AFF1 | chr4 | 87968747 | + | ENST00000389506 | KMT2A | chr11 | 118354896 | + | 11027 | 1458 | 420 | 9281 | 2953 |
| ENST00000307808 | AFF1 | chr4 | 87968747 | + | ENST00000354520 | KMT2A | chr11 | 118354896 | + | 11692 | 1458 | 420 | 9167 | 2915 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000395146 | ENST00000534358 | AFF1 | chr4 | 88005317 | + | KMT2A | chr11 | 118354896 | + | 0.000398544 | 0.9996014 |
| ENST00000395146 | ENST00000389506 | AFF1 | chr4 | 88005317 | + | KMT2A | chr11 | 118354896 | + | 0.00071558 | 0.99928445 |
| ENST00000395146 | ENST00000354520 | AFF1 | chr4 | 88005317 | + | KMT2A | chr11 | 118354896 | + | 0.000808311 | 0.9991917 |
| ENST00000307808 | ENST00000534358 | AFF1 | chr4 | 88005317 | + | KMT2A | chr11 | 118354896 | + | 0.000469441 | 0.99953055 |
| ENST00000307808 | ENST00000389506 | AFF1 | chr4 | 88005317 | + | KMT2A | chr11 | 118354896 | + | 0.000819157 | 0.99918085 |
| ENST00000307808 | ENST00000354520 | AFF1 | chr4 | 88005317 | + | KMT2A | chr11 | 118354896 | + | 0.000930167 | 0.99906987 |
| ENST00000395146 | ENST00000534358 | AFF1 | chr4 | 87968752 | + | KMT2A | chr11 | 118359327 | + | 0.000401693 | 0.9995983 |
| ENST00000395146 | ENST00000389506 | AFF1 | chr4 | 87968752 | + | KMT2A | chr11 | 118359327 | + | 0.000721473 | 0.9992785 |
| ENST00000395146 | ENST00000354520 | AFF1 | chr4 | 87968752 | + | KMT2A | chr11 | 118359327 | + | 0.000773512 | 0.99922645 |
| ENST00000307808 | ENST00000534358 | AFF1 | chr4 | 87968752 | + | KMT2A | chr11 | 118359327 | + | 0.000473139 | 0.99952686 |
| ENST00000307808 | ENST00000389506 | AFF1 | chr4 | 87968752 | + | KMT2A | chr11 | 118359327 | + | 0.000823493 | 0.99917644 |
| ENST00000307808 | ENST00000354520 | AFF1 | chr4 | 87968752 | + | KMT2A | chr11 | 118359327 | + | 0.000890003 | 0.9991099 |
| ENST00000395146 | ENST00000534358 | AFF1 | chr4 | 87968747 | + | KMT2A | chr11 | 118354896 | + | 0.00039502 | 0.999605 |
| ENST00000395146 | ENST00000389506 | AFF1 | chr4 | 87968747 | + | KMT2A | chr11 | 118354896 | + | 0.000705961 | 0.99929404 |
| ENST00000395146 | ENST00000354520 | AFF1 | chr4 | 87968747 | + | KMT2A | chr11 | 118354896 | + | 0.000798591 | 0.9992015 |
| ENST00000307808 | ENST00000534358 | AFF1 | chr4 | 87968747 | + | KMT2A | chr11 | 118354896 | + | 0.000465339 | 0.9995347 |
| ENST00000307808 | ENST00000389506 | AFF1 | chr4 | 87968747 | + | KMT2A | chr11 | 118354896 | + | 0.000808462 | 0.9991916 |
| ENST00000307808 | ENST00000354520 | AFF1 | chr4 | 87968747 | + | KMT2A | chr11 | 118354896 | + | 0.00091904 | 0.9990809 |
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Fusion Amino Acid Sequences |
| For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP >2660_2660_1_AFF1-KMT2A_AFF1_chr4_87967438_ENST00000307808_KMT2A_chr11_118354897_ENST00000354520_length(amino acids)=2615AA_BP=46 MAAQSSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKEKPPPVNKQENAGTLNILSTLSNGNSSKQKIPADGVHRIRVDFK FVYCQVCCEPFHKFCLEENERPLEDQLENWCCRRCKFCHVCGRQHQATKQLLECNKCRNSYHPECLGPNYPTKPTKKKKVWICTKCVRCK SCGSTTPGKGWDAQWSHDFSLCHDCAKLFAKGNFCPLCDKCYDDDDYESKMMQCGKCDRWVHSKCENLSDEMYEILSNLPESVAYTCVNC TERHPAEWRLALEKELQISLKQVLTALLNSRTTSHLLRYRQAAKPPDLNPETEESIPSRSSPEGPDPPVLTEVSKQDDQQPLDLEGVKRK MDQGNYTSVLEFSDDIVKIIQAAINSDGGQPEIKKANSMVKSFFIRQMERVFPWFSVKKSRFWEPNKVSSNSGMLPNAVLPPSLDHNYAQ WQEREENSHTEQPPLMKKIIPAPKPKGPGEPDSPTPLHPPTPPILSTDRSREDSPELNPPPGIEDNRQCALCLTYGDDSANDAGRLLYIG QNEWTHVNCALWSAEVFEDDDGSLKNVHMAVIRGKQLRCEFCQKPGATVGCCLTSCTSNYHFMCSRAKNCVFLDDKKVYCQRHRDLIKGE VVPENGFEVFRRVFVDFEGISLRRKFLNGLEPENIHMMIGSMTIDCLGILNDLSDCEDKLFPIGYQCSRVYWSTTDARKRCVYTCKIVEC RPPVVEPDINSTVEHDENRTIAHSPTSFTESSSKESQNTAEIISPPSPDRPPHSQTSGSCYYHVISKVPRIRTPSYSPTQRSPGCRPLPS AGSPTPTTHEIVTVGDPLLSSGLRSIGSRRHSTSSLSPQRSKLRIMSPMRTGNTYSRNNVSSVSTTGTATDLESSAKVVDHVLGPLNSST SLGQNTSTSSNLQRTVVTVGNKNSHLDGSSSSEMKQSSASDLVSKSSSLKGEKTKVLSSKSSEGSAHNVAYPGIPKLAPQVHNTTSRELN VSKIGSFAEPSSVSFSSKEALSFPHLHLRGQRNDRDQHTDSTQSANSSPDEDTEVKTLKLSGMSNRSSIINEHMGSSSRDRRQKGKKSCK ETFKEKHSSKSFLEPGQVTTGEEGNLKPEFMDEVLTPEYMGQRPCNNVSSDKIGDKGLSMPGVPKAPPMQVEGSAKELQAPRKRTVKVTL TPLKMENESQSKNALKESSPASPLQIESTSPTEPISASENPGDGPVAQPSPNNTSCQDSQSNNYQNLPVQDRNLMLPDGPKPQEDGSFKR RYPRRSARARSNMFFGLTPLYGVRSYGEEDIPFYSSSTGKKRGKRSAEGQVDGADDLSTSDEDDLYYYNFTRTVISSGGEERLASHNLFR EEEQCDLPKISQLDGVDDGTESDTSVTATTRKSSQIPKRNGKENGTENLKIDRPEDAGEKEHVTKSSVGHKNEPKMDNCHSVSRVKTQGQ DSLEAQLSSLESSRRVHTSTPSDKNLLDTYNTELLKSDSDNNNSDDCGNILPSDIMDFVLKNTPSMQALGESPESSSSELLNLGEGLGLD SNREKDMGLFEVFSQQLPTTEPVDSSVSSSISAEEQFELPLELPSDLSVLTTRSPTVPSQNPSRLAVISDSGEKRVTITEKSVASSESDP ALLSPGVDPTPEGHMTPDHFIQGHMDADHISSPPCGSVEQGHGNNQDLTRNSSTPGLQVPVSPTVPIQNQKYVPNSTDSPGPSQISNAAV QTTPPHLKPATEKLIVVNQNMQPLYVLQTLPNGVTQKIQLTSSVSSTPSVMETNTSVLGPMGGGLTLTTGLNPSLPTSQSLFPSASKGLL PMSHHQHLHSFPAATQSSFPPNISNPPSGLLIGVQPPPDPQLLVSESSQRTDLSTTVATPSSGLKKRPISRLQTRKNKKLAPSSTPSNIA PSDVVSNMTLINFTPSQLPNHPSLLDLGSLNTSSHRTVPNIIKRSKSSIMYFEPAPLLPQSVGGTAATAAGTSTISQDTSHLTSGSVSGL ASSSSVLNVVSMQTTTTPTSSASVPGHVTLTNPRLLGTPDIGSISNLLIKASQQSLGIQDQPVALPPSSGMFPQLGTSQTPSTAAITAAS SICVLPSTQTTGITAASPSGEADEHYQLQHVNQLLASKTGIHSSQRDLDSASGPQVSNFTQTVDAPNSMGLEQNKALSSAVQASPTSPGG SPSSPSSGQRSASPSVPGPTKPKPKTKRFQLPLDKGNGKKHKVSHLRTSSSEAHIPDQETTSLTSGTGTPGAEAEQQDTASVEQSSQKEC GQPAGQVAVLPEVQVTQNPANEQESAEPKTVEEEESNFSSPLMLWLQQEQKRKESITEKKPKKGLVFEISSDDGFQICAESIEDAWKSLT DKVQEARSNARLKQLSFAGVNGLRMLGILHDAVVFLIEQLSGAKHCRNYKFRFHKPEEANEPPLNPHGSARAEVHLRKSAFDMFNFLASK HRQPPEYNPNDEEEEEVQLKSARRATSMDLPMPMRFRHLKKTSKEAVGVYRSPIHGRGLFCKRNIDAGEMVIEYAGNVIRSIQTDKREKY YDSKGIGCYMFRIDDSEVVDATMHGNAARFINHSCEPNCYSRVINIDGQKHIVIFAMRKIYRGEELTYDYKFPIEDASNKLPCNCGAKKC -------------------------------------------------------------- >2660_2660_2_AFF1-KMT2A_AFF1_chr4_87967438_ENST00000307808_KMT2A_chr11_118354897_ENST00000389506_length(amino acids)=2653AA_BP=46 MAAQSSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKEKPPPVNKQENAGTLNILSTLSNGNSSKQKIPADGVHRIRVDFK EDCEAENVWEMGGLGILTSVPITPRVVCFLCASSGHVEFVYCQVCCEPFHKFCLEENERPLEDQLENWCCRRCKFCHVCGRQHQATKQLL ECNKCRNSYHPECLGPNYPTKPTKKKKVWICTKCVRCKSCGSTTPGKGWDAQWSHDFSLCHDCAKLFAKGNFCPLCDKCYDDDDYESKMM QCGKCDRWVHSKCENLSDEMYEILSNLPESVAYTCVNCTERHPAEWRLALEKELQISLKQVLTALLNSRTTSHLLRYRQAAKPPDLNPET EESIPSRSSPEGPDPPVLTEVSKQDDQQPLDLEGVKRKMDQGNYTSVLEFSDDIVKIIQAAINSDGGQPEIKKANSMVKSFFIRQMERVF PWFSVKKSRFWEPNKVSSNSGMLPNAVLPPSLDHNYAQWQEREENSHTEQPPLMKKIIPAPKPKGPGEPDSPTPLHPPTPPILSTDRSRE DSPELNPPPGIEDNRQCALCLTYGDDSANDAGRLLYIGQNEWTHVNCALWSAEVFEDDDGSLKNVHMAVIRGKQLRCEFCQKPGATVGCC LTSCTSNYHFMCSRAKNCVFLDDKKVYCQRHRDLIKGEVVPENGFEVFRRVFVDFEGISLRRKFLNGLEPENIHMMIGSMTIDCLGILND LSDCEDKLFPIGYQCSRVYWSTTDARKRCVYTCKIVECRPPVVEPDINSTVEHDENRTIAHSPTSFTESSSKESQNTAEIISPPSPDRPP HSQTSGSCYYHVISKVPRIRTPSYSPTQRSPGCRPLPSAGSPTPTTHEIVTVGDPLLSSGLRSIGSRRHSTSSLSPQRSKLRIMSPMRTG NTYSRNNVSSVSTTGTATDLESSAKVVDHVLGPLNSSTSLGQNTSTSSNLQRTVVTVGNKNSHLDGSSSSEMKQSSASDLVSKSSSLKGE KTKVLSSKSSEGSAHNVAYPGIPKLAPQVHNTTSRELNVSKIGSFAEPSSVSFSSKEALSFPHLHLRGQRNDRDQHTDSTQSANSSPDED TEVKTLKLSGMSNRSSIINEHMGSSSRDRRQKGKKSCKETFKEKHSSKSFLEPGQVTTGEEGNLKPEFMDEVLTPEYMGQRPCNNVSSDK IGDKGLSMPGVPKAPPMQVEGSAKELQAPRKRTVKVTLTPLKMENESQSKNALKESSPASPLQIESTSPTEPISASENPGDGPVAQPSPN NTSCQDSQSNNYQNLPVQDRNLMLPDGPKPQEDGSFKRRYPRRSARARSNMFFGLTPLYGVRSYGEEDIPFYSSSTGKKRGKRSAEGQVD GADDLSTSDEDDLYYYNFTRTVISSGGEERLASHNLFREEEQCDLPKISQLDGVDDGTESDTSVTATTRKSSQIPKRNGKENGTENLKID RPEDAGEKEHVTKSSVGHKNEPKMDNCHSVSRVKTQGQDSLEAQLSSLESSRRVHTSTPSDKNLLDTYNTELLKSDSDNNNSDDCGNILP SDIMDFVLKNTPSMQALGESPESSSSELLNLGEGLGLDSNREKDMGLFEVFSQQLPTTEPVDSSVSSSISAEEQFELPLELPSDLSVLTT RSPTVPSQNPSRLAVISDSGEKRVTITEKSVASSESDPALLSPGVDPTPEGHMTPDHFIQGHMDADHISSPPCGSVEQGHGNNQDLTRNS STPGLQVPVSPTVPIQNQKYVPNSTDSPGPSQISNAAVQTTPPHLKPATEKLIVVNQNMQPLYVLQTLPNGVTQKIQLTSSVSSTPSVME TNTSVLGPMGGGLTLTTGLNPSLPTSQSLFPSASKGLLPMSHHQHLHSFPAATQSSFPPNISNPPSGLLIGVQPPPDPQLLVSESSQRTD LSTTVATPSSGLKKRPISRLQTRKNKKLAPSSTPSNIAPSDVVSNMTLINFTPSQLPNHPSLLDLGSLNTSSHRTVPNIIKRSKSSIMYF EPAPLLPQSVGGTAATAAGTSTISQDTSHLTSGSVSGLASSSSVLNVVSMQTTTTPTSSASVPGHVTLTNPRLLGTPDIGSISNLLIKAS QQSLGIQDQPVALPPSSGMFPQLGTSQTPSTAAITAASSICVLPSTQTTGITAASPSGEADEHYQLQHVNQLLASKTGIHSSQRDLDSAS GPQVSNFTQTVDAPNSMGLEQNKALSSAVQASPTSPGGSPSSPSSGQRSASPSVPGPTKPKPKTKRFQLPLDKGNGKKHKVSHLRTSSSE AHIPDQETTSLTSGTGTPGAEAEQQDTASVEQSSQKECGQPAGQVAVLPEVQVTQNPANEQESAEPKTVEEEESNFSSPLMLWLQQEQKR KESITEKKPKKGLVFEISSDDGFQICAESIEDAWKSLTDKVQEARSNARLKQLSFAGVNGLRMLGILHDAVVFLIEQLSGAKHCRNYKFR FHKPEEANEPPLNPHGSARAEVHLRKSAFDMFNFLASKHRQPPEYNPNDEEEEEVQLKSARRATSMDLPMPMRFRHLKKTSKEAVGVYRS PIHGRGLFCKRNIDAGEMVIEYAGNVIRSIQTDKREKYYDSKGIGCYMFRIDDSEVVDATMHGNAARFINHSCEPNCYSRVINIDGQKHI -------------------------------------------------------------- >2660_2660_3_AFF1-KMT2A_AFF1_chr4_87967438_ENST00000307808_KMT2A_chr11_118354897_ENST00000534358_length(amino acids)=2656AA_BP=46 MAAQSSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKEKPPPVNKQENAGTLNILSTLSNGNSSKQKIPADGVHRIRVDFK EDCEAENVWEMGGLGILTSVPITPRVVCFLCASSGHVEFVYCQVCCEPFHKFCLEENERPLEDQLENWCCRRCKFCHVCGRQHQATKQLL ECNKCRNSYHPECLGPNYPTKPTKKKKVWICTKCVRCKSCGSTTPGKGWDAQWSHDFSLCHDCAKLFAKGNFCPLCDKCYDDDDYESKMM QCGKCDRWVHSKCENLSGTEDEMYEILSNLPESVAYTCVNCTERHPAEWRLALEKELQISLKQVLTALLNSRTTSHLLRYRQAAKPPDLN PETEESIPSRSSPEGPDPPVLTEVSKQDDQQPLDLEGVKRKMDQGNYTSVLEFSDDIVKIIQAAINSDGGQPEIKKANSMVKSFFIRQME RVFPWFSVKKSRFWEPNKVSSNSGMLPNAVLPPSLDHNYAQWQEREENSHTEQPPLMKKIIPAPKPKGPGEPDSPTPLHPPTPPILSTDR SREDSPELNPPPGIEDNRQCALCLTYGDDSANDAGRLLYIGQNEWTHVNCALWSAEVFEDDDGSLKNVHMAVIRGKQLRCEFCQKPGATV GCCLTSCTSNYHFMCSRAKNCVFLDDKKVYCQRHRDLIKGEVVPENGFEVFRRVFVDFEGISLRRKFLNGLEPENIHMMIGSMTIDCLGI LNDLSDCEDKLFPIGYQCSRVYWSTTDARKRCVYTCKIVECRPPVVEPDINSTVEHDENRTIAHSPTSFTESSSKESQNTAEIISPPSPD RPPHSQTSGSCYYHVISKVPRIRTPSYSPTQRSPGCRPLPSAGSPTPTTHEIVTVGDPLLSSGLRSIGSRRHSTSSLSPQRSKLRIMSPM RTGNTYSRNNVSSVSTTGTATDLESSAKVVDHVLGPLNSSTSLGQNTSTSSNLQRTVVTVGNKNSHLDGSSSSEMKQSSASDLVSKSSSL KGEKTKVLSSKSSEGSAHNVAYPGIPKLAPQVHNTTSRELNVSKIGSFAEPSSVSFSSKEALSFPHLHLRGQRNDRDQHTDSTQSANSSP DEDTEVKTLKLSGMSNRSSIINEHMGSSSRDRRQKGKKSCKETFKEKHSSKSFLEPGQVTTGEEGNLKPEFMDEVLTPEYMGQRPCNNVS SDKIGDKGLSMPGVPKAPPMQVEGSAKELQAPRKRTVKVTLTPLKMENESQSKNALKESSPASPLQIESTSPTEPISASENPGDGPVAQP SPNNTSCQDSQSNNYQNLPVQDRNLMLPDGPKPQEDGSFKRRYPRRSARARSNMFFGLTPLYGVRSYGEEDIPFYSSSTGKKRGKRSAEG QVDGADDLSTSDEDDLYYYNFTRTVISSGGEERLASHNLFREEEQCDLPKISQLDGVDDGTESDTSVTATTRKSSQIPKRNGKENGTENL KIDRPEDAGEKEHVTKSSVGHKNEPKMDNCHSVSRVKTQGQDSLEAQLSSLESSRRVHTSTPSDKNLLDTYNTELLKSDSDNNNSDDCGN ILPSDIMDFVLKNTPSMQALGESPESSSSELLNLGEGLGLDSNREKDMGLFEVFSQQLPTTEPVDSSVSSSISAEEQFELPLELPSDLSV LTTRSPTVPSQNPSRLAVISDSGEKRVTITEKSVASSESDPALLSPGVDPTPEGHMTPDHFIQGHMDADHISSPPCGSVEQGHGNNQDLT RNSSTPGLQVPVSPTVPIQNQKYVPNSTDSPGPSQISNAAVQTTPPHLKPATEKLIVVNQNMQPLYVLQTLPNGVTQKIQLTSSVSSTPS VMETNTSVLGPMGGGLTLTTGLNPSLPTSQSLFPSASKGLLPMSHHQHLHSFPAATQSSFPPNISNPPSGLLIGVQPPPDPQLLVSESSQ RTDLSTTVATPSSGLKKRPISRLQTRKNKKLAPSSTPSNIAPSDVVSNMTLINFTPSQLPNHPSLLDLGSLNTSSHRTVPNIIKRSKSSI MYFEPAPLLPQSVGGTAATAAGTSTISQDTSHLTSGSVSGLASSSSVLNVVSMQTTTTPTSSASVPGHVTLTNPRLLGTPDIGSISNLLI KASQQSLGIQDQPVALPPSSGMFPQLGTSQTPSTAAITAASSICVLPSTQTTGITAASPSGEADEHYQLQHVNQLLASKTGIHSSQRDLD SASGPQVSNFTQTVDAPNSMGLEQNKALSSAVQASPTSPGGSPSSPSSGQRSASPSVPGPTKPKPKTKRFQLPLDKGNGKKHKVSHLRTS SSEAHIPDQETTSLTSGTGTPGAEAEQQDTASVEQSSQKECGQPAGQVAVLPEVQVTQNPANEQESAEPKTVEEEESNFSSPLMLWLQQE QKRKESITEKKPKKGLVFEISSDDGFQICAESIEDAWKSLTDKVQEARSNARLKQLSFAGVNGLRMLGILHDAVVFLIEQLSGAKHCRNY KFRFHKPEEANEPPLNPHGSARAEVHLRKSAFDMFNFLASKHRQPPEYNPNDEEEEEVQLKSARRATSMDLPMPMRFRHLKKTSKEAVGV YRSPIHGRGLFCKRNIDAGEMVIEYAGNVIRSIQTDKREKYYDSKGIGCYMFRIDDSEVVDATMHGNAARFINHSCEPNCYSRVINIDGQ -------------------------------------------------------------- >2660_2660_4_AFF1-KMT2A_AFF1_chr4_87967438_ENST00000307808_KMT2A_chr11_118359328_ENST00000354520_length(amino acids)=2571AA_BP=46 MAAQSSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKFVYCQVCCEPFHKFCLEENERPLEDQLENWCCRRCKFCHVCGRQ HQATKQLLECNKCRNSYHPECLGPNYPTKPTKKKKVWICTKCVRCKSCGSTTPGKGWDAQWSHDFSLCHDCAKLFAKGNFCPLCDKCYDD DDYESKMMQCGKCDRWVHSKCENLSDEMYEILSNLPESVAYTCVNCTERHPAEWRLALEKELQISLKQVLTALLNSRTTSHLLRYRQAAK PPDLNPETEESIPSRSSPEGPDPPVLTEVSKQDDQQPLDLEGVKRKMDQGNYTSVLEFSDDIVKIIQAAINSDGGQPEIKKANSMVKSFF IRQMERVFPWFSVKKSRFWEPNKVSSNSGMLPNAVLPPSLDHNYAQWQEREENSHTEQPPLMKKIIPAPKPKGPGEPDSPTPLHPPTPPI LSTDRSREDSPELNPPPGIEDNRQCALCLTYGDDSANDAGRLLYIGQNEWTHVNCALWSAEVFEDDDGSLKNVHMAVIRGKQLRCEFCQK PGATVGCCLTSCTSNYHFMCSRAKNCVFLDDKKVYCQRHRDLIKGEVVPENGFEVFRRVFVDFEGISLRRKFLNGLEPENIHMMIGSMTI DCLGILNDLSDCEDKLFPIGYQCSRVYWSTTDARKRCVYTCKIVECRPPVVEPDINSTVEHDENRTIAHSPTSFTESSSKESQNTAEIIS PPSPDRPPHSQTSGSCYYHVISKVPRIRTPSYSPTQRSPGCRPLPSAGSPTPTTHEIVTVGDPLLSSGLRSIGSRRHSTSSLSPQRSKLR IMSPMRTGNTYSRNNVSSVSTTGTATDLESSAKVVDHVLGPLNSSTSLGQNTSTSSNLQRTVVTVGNKNSHLDGSSSSEMKQSSASDLVS KSSSLKGEKTKVLSSKSSEGSAHNVAYPGIPKLAPQVHNTTSRELNVSKIGSFAEPSSVSFSSKEALSFPHLHLRGQRNDRDQHTDSTQS ANSSPDEDTEVKTLKLSGMSNRSSIINEHMGSSSRDRRQKGKKSCKETFKEKHSSKSFLEPGQVTTGEEGNLKPEFMDEVLTPEYMGQRP CNNVSSDKIGDKGLSMPGVPKAPPMQVEGSAKELQAPRKRTVKVTLTPLKMENESQSKNALKESSPASPLQIESTSPTEPISASENPGDG PVAQPSPNNTSCQDSQSNNYQNLPVQDRNLMLPDGPKPQEDGSFKRRYPRRSARARSNMFFGLTPLYGVRSYGEEDIPFYSSSTGKKRGK RSAEGQVDGADDLSTSDEDDLYYYNFTRTVISSGGEERLASHNLFREEEQCDLPKISQLDGVDDGTESDTSVTATTRKSSQIPKRNGKEN GTENLKIDRPEDAGEKEHVTKSSVGHKNEPKMDNCHSVSRVKTQGQDSLEAQLSSLESSRRVHTSTPSDKNLLDTYNTELLKSDSDNNNS DDCGNILPSDIMDFVLKNTPSMQALGESPESSSSELLNLGEGLGLDSNREKDMGLFEVFSQQLPTTEPVDSSVSSSISAEEQFELPLELP SDLSVLTTRSPTVPSQNPSRLAVISDSGEKRVTITEKSVASSESDPALLSPGVDPTPEGHMTPDHFIQGHMDADHISSPPCGSVEQGHGN NQDLTRNSSTPGLQVPVSPTVPIQNQKYVPNSTDSPGPSQISNAAVQTTPPHLKPATEKLIVVNQNMQPLYVLQTLPNGVTQKIQLTSSV SSTPSVMETNTSVLGPMGGGLTLTTGLNPSLPTSQSLFPSASKGLLPMSHHQHLHSFPAATQSSFPPNISNPPSGLLIGVQPPPDPQLLV SESSQRTDLSTTVATPSSGLKKRPISRLQTRKNKKLAPSSTPSNIAPSDVVSNMTLINFTPSQLPNHPSLLDLGSLNTSSHRTVPNIIKR SKSSIMYFEPAPLLPQSVGGTAATAAGTSTISQDTSHLTSGSVSGLASSSSVLNVVSMQTTTTPTSSASVPGHVTLTNPRLLGTPDIGSI SNLLIKASQQSLGIQDQPVALPPSSGMFPQLGTSQTPSTAAITAASSICVLPSTQTTGITAASPSGEADEHYQLQHVNQLLASKTGIHSS QRDLDSASGPQVSNFTQTVDAPNSMGLEQNKALSSAVQASPTSPGGSPSSPSSGQRSASPSVPGPTKPKPKTKRFQLPLDKGNGKKHKVS HLRTSSSEAHIPDQETTSLTSGTGTPGAEAEQQDTASVEQSSQKECGQPAGQVAVLPEVQVTQNPANEQESAEPKTVEEEESNFSSPLML WLQQEQKRKESITEKKPKKGLVFEISSDDGFQICAESIEDAWKSLTDKVQEARSNARLKQLSFAGVNGLRMLGILHDAVVFLIEQLSGAK HCRNYKFRFHKPEEANEPPLNPHGSARAEVHLRKSAFDMFNFLASKHRQPPEYNPNDEEEEEVQLKSARRATSMDLPMPMRFRHLKKTSK EAVGVYRSPIHGRGLFCKRNIDAGEMVIEYAGNVIRSIQTDKREKYYDSKGIGCYMFRIDDSEVVDATMHGNAARFINHSCEPNCYSRVI -------------------------------------------------------------- >2660_2660_5_AFF1-KMT2A_AFF1_chr4_87967438_ENST00000307808_KMT2A_chr11_118359328_ENST00000389506_length(amino acids)=2571AA_BP=46 MAAQSSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKFVYCQVCCEPFHKFCLEENERPLEDQLENWCCRRCKFCHVCGRQ HQATKQLLECNKCRNSYHPECLGPNYPTKPTKKKKVWICTKCVRCKSCGSTTPGKGWDAQWSHDFSLCHDCAKLFAKGNFCPLCDKCYDD DDYESKMMQCGKCDRWVHSKCENLSDEMYEILSNLPESVAYTCVNCTERHPAEWRLALEKELQISLKQVLTALLNSRTTSHLLRYRQAAK PPDLNPETEESIPSRSSPEGPDPPVLTEVSKQDDQQPLDLEGVKRKMDQGNYTSVLEFSDDIVKIIQAAINSDGGQPEIKKANSMVKSFF IRQMERVFPWFSVKKSRFWEPNKVSSNSGMLPNAVLPPSLDHNYAQWQEREENSHTEQPPLMKKIIPAPKPKGPGEPDSPTPLHPPTPPI LSTDRSREDSPELNPPPGIEDNRQCALCLTYGDDSANDAGRLLYIGQNEWTHVNCALWSAEVFEDDDGSLKNVHMAVIRGKQLRCEFCQK PGATVGCCLTSCTSNYHFMCSRAKNCVFLDDKKVYCQRHRDLIKGEVVPENGFEVFRRVFVDFEGISLRRKFLNGLEPENIHMMIGSMTI DCLGILNDLSDCEDKLFPIGYQCSRVYWSTTDARKRCVYTCKIVECRPPVVEPDINSTVEHDENRTIAHSPTSFTESSSKESQNTAEIIS PPSPDRPPHSQTSGSCYYHVISKVPRIRTPSYSPTQRSPGCRPLPSAGSPTPTTHEIVTVGDPLLSSGLRSIGSRRHSTSSLSPQRSKLR IMSPMRTGNTYSRNNVSSVSTTGTATDLESSAKVVDHVLGPLNSSTSLGQNTSTSSNLQRTVVTVGNKNSHLDGSSSSEMKQSSASDLVS KSSSLKGEKTKVLSSKSSEGSAHNVAYPGIPKLAPQVHNTTSRELNVSKIGSFAEPSSVSFSSKEALSFPHLHLRGQRNDRDQHTDSTQS ANSSPDEDTEVKTLKLSGMSNRSSIINEHMGSSSRDRRQKGKKSCKETFKEKHSSKSFLEPGQVTTGEEGNLKPEFMDEVLTPEYMGQRP CNNVSSDKIGDKGLSMPGVPKAPPMQVEGSAKELQAPRKRTVKVTLTPLKMENESQSKNALKESSPASPLQIESTSPTEPISASENPGDG PVAQPSPNNTSCQDSQSNNYQNLPVQDRNLMLPDGPKPQEDGSFKRRYPRRSARARSNMFFGLTPLYGVRSYGEEDIPFYSSSTGKKRGK RSAEGQVDGADDLSTSDEDDLYYYNFTRTVISSGGEERLASHNLFREEEQCDLPKISQLDGVDDGTESDTSVTATTRKSSQIPKRNGKEN GTENLKIDRPEDAGEKEHVTKSSVGHKNEPKMDNCHSVSRVKTQGQDSLEAQLSSLESSRRVHTSTPSDKNLLDTYNTELLKSDSDNNNS DDCGNILPSDIMDFVLKNTPSMQALGESPESSSSELLNLGEGLGLDSNREKDMGLFEVFSQQLPTTEPVDSSVSSSISAEEQFELPLELP SDLSVLTTRSPTVPSQNPSRLAVISDSGEKRVTITEKSVASSESDPALLSPGVDPTPEGHMTPDHFIQGHMDADHISSPPCGSVEQGHGN NQDLTRNSSTPGLQVPVSPTVPIQNQKYVPNSTDSPGPSQISNAAVQTTPPHLKPATEKLIVVNQNMQPLYVLQTLPNGVTQKIQLTSSV SSTPSVMETNTSVLGPMGGGLTLTTGLNPSLPTSQSLFPSASKGLLPMSHHQHLHSFPAATQSSFPPNISNPPSGLLIGVQPPPDPQLLV SESSQRTDLSTTVATPSSGLKKRPISRLQTRKNKKLAPSSTPSNIAPSDVVSNMTLINFTPSQLPNHPSLLDLGSLNTSSHRTVPNIIKR SKSSIMYFEPAPLLPQSVGGTAATAAGTSTISQDTSHLTSGSVSGLASSSSVLNVVSMQTTTTPTSSASVPGHVTLTNPRLLGTPDIGSI SNLLIKASQQSLGIQDQPVALPPSSGMFPQLGTSQTPSTAAITAASSICVLPSTQTTGITAASPSGEADEHYQLQHVNQLLASKTGIHSS QRDLDSASGPQVSNFTQTVDAPNSMGLEQNKALSSAVQASPTSPGGSPSSPSSGQRSASPSVPGPTKPKPKTKRFQLPLDKGNGKKHKVS HLRTSSSEAHIPDQETTSLTSGTGTPGAEAEQQDTASVEQSSQKECGQPAGQVAVLPEVQVTQNPANEQESAEPKTVEEEESNFSSPLML WLQQEQKRKESITEKKPKKGLVFEISSDDGFQICAESIEDAWKSLTDKVQEARSNARLKQLSFAGVNGLRMLGILHDAVVFLIEQLSGAK HCRNYKFRFHKPEEANEPPLNPHGSARAEVHLRKSAFDMFNFLASKHRQPPEYNPNDEEEEEVQLKSARRATSMDLPMPMRFRHLKKTSK EAVGVYRSPIHGRGLFCKRNIDAGEMVIEYAGNVIRSIQTDKREKYYDSKGIGCYMFRIDDSEVVDATMHGNAARFINHSCEPNCYSRVI -------------------------------------------------------------- >2660_2660_6_AFF1-KMT2A_AFF1_chr4_87967438_ENST00000307808_KMT2A_chr11_118359328_ENST00000534358_length(amino acids)=2574AA_BP=46 MAAQSSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKFVYCQVCCEPFHKFCLEENERPLEDQLENWCCRRCKFCHVCGRQ HQATKQLLECNKCRNSYHPECLGPNYPTKPTKKKKVWICTKCVRCKSCGSTTPGKGWDAQWSHDFSLCHDCAKLFAKGNFCPLCDKCYDD DDYESKMMQCGKCDRWVHSKCENLSGTEDEMYEILSNLPESVAYTCVNCTERHPAEWRLALEKELQISLKQVLTALLNSRTTSHLLRYRQ AAKPPDLNPETEESIPSRSSPEGPDPPVLTEVSKQDDQQPLDLEGVKRKMDQGNYTSVLEFSDDIVKIIQAAINSDGGQPEIKKANSMVK SFFIRQMERVFPWFSVKKSRFWEPNKVSSNSGMLPNAVLPPSLDHNYAQWQEREENSHTEQPPLMKKIIPAPKPKGPGEPDSPTPLHPPT PPILSTDRSREDSPELNPPPGIEDNRQCALCLTYGDDSANDAGRLLYIGQNEWTHVNCALWSAEVFEDDDGSLKNVHMAVIRGKQLRCEF CQKPGATVGCCLTSCTSNYHFMCSRAKNCVFLDDKKVYCQRHRDLIKGEVVPENGFEVFRRVFVDFEGISLRRKFLNGLEPENIHMMIGS MTIDCLGILNDLSDCEDKLFPIGYQCSRVYWSTTDARKRCVYTCKIVECRPPVVEPDINSTVEHDENRTIAHSPTSFTESSSKESQNTAE IISPPSPDRPPHSQTSGSCYYHVISKVPRIRTPSYSPTQRSPGCRPLPSAGSPTPTTHEIVTVGDPLLSSGLRSIGSRRHSTSSLSPQRS KLRIMSPMRTGNTYSRNNVSSVSTTGTATDLESSAKVVDHVLGPLNSSTSLGQNTSTSSNLQRTVVTVGNKNSHLDGSSSSEMKQSSASD LVSKSSSLKGEKTKVLSSKSSEGSAHNVAYPGIPKLAPQVHNTTSRELNVSKIGSFAEPSSVSFSSKEALSFPHLHLRGQRNDRDQHTDS TQSANSSPDEDTEVKTLKLSGMSNRSSIINEHMGSSSRDRRQKGKKSCKETFKEKHSSKSFLEPGQVTTGEEGNLKPEFMDEVLTPEYMG QRPCNNVSSDKIGDKGLSMPGVPKAPPMQVEGSAKELQAPRKRTVKVTLTPLKMENESQSKNALKESSPASPLQIESTSPTEPISASENP GDGPVAQPSPNNTSCQDSQSNNYQNLPVQDRNLMLPDGPKPQEDGSFKRRYPRRSARARSNMFFGLTPLYGVRSYGEEDIPFYSSSTGKK RGKRSAEGQVDGADDLSTSDEDDLYYYNFTRTVISSGGEERLASHNLFREEEQCDLPKISQLDGVDDGTESDTSVTATTRKSSQIPKRNG KENGTENLKIDRPEDAGEKEHVTKSSVGHKNEPKMDNCHSVSRVKTQGQDSLEAQLSSLESSRRVHTSTPSDKNLLDTYNTELLKSDSDN NNSDDCGNILPSDIMDFVLKNTPSMQALGESPESSSSELLNLGEGLGLDSNREKDMGLFEVFSQQLPTTEPVDSSVSSSISAEEQFELPL ELPSDLSVLTTRSPTVPSQNPSRLAVISDSGEKRVTITEKSVASSESDPALLSPGVDPTPEGHMTPDHFIQGHMDADHISSPPCGSVEQG HGNNQDLTRNSSTPGLQVPVSPTVPIQNQKYVPNSTDSPGPSQISNAAVQTTPPHLKPATEKLIVVNQNMQPLYVLQTLPNGVTQKIQLT SSVSSTPSVMETNTSVLGPMGGGLTLTTGLNPSLPTSQSLFPSASKGLLPMSHHQHLHSFPAATQSSFPPNISNPPSGLLIGVQPPPDPQ LLVSESSQRTDLSTTVATPSSGLKKRPISRLQTRKNKKLAPSSTPSNIAPSDVVSNMTLINFTPSQLPNHPSLLDLGSLNTSSHRTVPNI IKRSKSSIMYFEPAPLLPQSVGGTAATAAGTSTISQDTSHLTSGSVSGLASSSSVLNVVSMQTTTTPTSSASVPGHVTLTNPRLLGTPDI GSISNLLIKASQQSLGIQDQPVALPPSSGMFPQLGTSQTPSTAAITAASSICVLPSTQTTGITAASPSGEADEHYQLQHVNQLLASKTGI HSSQRDLDSASGPQVSNFTQTVDAPNSMGLEQNKALSSAVQASPTSPGGSPSSPSSGQRSASPSVPGPTKPKPKTKRFQLPLDKGNGKKH KVSHLRTSSSEAHIPDQETTSLTSGTGTPGAEAEQQDTASVEQSSQKECGQPAGQVAVLPEVQVTQNPANEQESAEPKTVEEEESNFSSP LMLWLQQEQKRKESITEKKPKKGLVFEISSDDGFQICAESIEDAWKSLTDKVQEARSNARLKQLSFAGVNGLRMLGILHDAVVFLIEQLS GAKHCRNYKFRFHKPEEANEPPLNPHGSARAEVHLRKSAFDMFNFLASKHRQPPEYNPNDEEEEEVQLKSARRATSMDLPMPMRFRHLKK TSKEAVGVYRSPIHGRGLFCKRNIDAGEMVIEYAGNVIRSIQTDKREKYYDSKGIGCYMFRIDDSEVVDATMHGNAARFINHSCEPNCYS -------------------------------------------------------------- >2660_2660_7_AFF1-KMT2A_AFF1_chr4_87967438_ENST00000395146_KMT2A_chr11_118354897_ENST00000354520_length(amino acids)=2625AA_BP=56 METMAFTERVNSSGNSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKEKPPPVNKQENAGTLNILSTLSNGNSSKQKIPAD GVHRIRVDFKFVYCQVCCEPFHKFCLEENERPLEDQLENWCCRRCKFCHVCGRQHQATKQLLECNKCRNSYHPECLGPNYPTKPTKKKKV WICTKCVRCKSCGSTTPGKGWDAQWSHDFSLCHDCAKLFAKGNFCPLCDKCYDDDDYESKMMQCGKCDRWVHSKCENLSDEMYEILSNLP ESVAYTCVNCTERHPAEWRLALEKELQISLKQVLTALLNSRTTSHLLRYRQAAKPPDLNPETEESIPSRSSPEGPDPPVLTEVSKQDDQQ PLDLEGVKRKMDQGNYTSVLEFSDDIVKIIQAAINSDGGQPEIKKANSMVKSFFIRQMERVFPWFSVKKSRFWEPNKVSSNSGMLPNAVL PPSLDHNYAQWQEREENSHTEQPPLMKKIIPAPKPKGPGEPDSPTPLHPPTPPILSTDRSREDSPELNPPPGIEDNRQCALCLTYGDDSA NDAGRLLYIGQNEWTHVNCALWSAEVFEDDDGSLKNVHMAVIRGKQLRCEFCQKPGATVGCCLTSCTSNYHFMCSRAKNCVFLDDKKVYC QRHRDLIKGEVVPENGFEVFRRVFVDFEGISLRRKFLNGLEPENIHMMIGSMTIDCLGILNDLSDCEDKLFPIGYQCSRVYWSTTDARKR CVYTCKIVECRPPVVEPDINSTVEHDENRTIAHSPTSFTESSSKESQNTAEIISPPSPDRPPHSQTSGSCYYHVISKVPRIRTPSYSPTQ RSPGCRPLPSAGSPTPTTHEIVTVGDPLLSSGLRSIGSRRHSTSSLSPQRSKLRIMSPMRTGNTYSRNNVSSVSTTGTATDLESSAKVVD HVLGPLNSSTSLGQNTSTSSNLQRTVVTVGNKNSHLDGSSSSEMKQSSASDLVSKSSSLKGEKTKVLSSKSSEGSAHNVAYPGIPKLAPQ VHNTTSRELNVSKIGSFAEPSSVSFSSKEALSFPHLHLRGQRNDRDQHTDSTQSANSSPDEDTEVKTLKLSGMSNRSSIINEHMGSSSRD RRQKGKKSCKETFKEKHSSKSFLEPGQVTTGEEGNLKPEFMDEVLTPEYMGQRPCNNVSSDKIGDKGLSMPGVPKAPPMQVEGSAKELQA PRKRTVKVTLTPLKMENESQSKNALKESSPASPLQIESTSPTEPISASENPGDGPVAQPSPNNTSCQDSQSNNYQNLPVQDRNLMLPDGP KPQEDGSFKRRYPRRSARARSNMFFGLTPLYGVRSYGEEDIPFYSSSTGKKRGKRSAEGQVDGADDLSTSDEDDLYYYNFTRTVISSGGE ERLASHNLFREEEQCDLPKISQLDGVDDGTESDTSVTATTRKSSQIPKRNGKENGTENLKIDRPEDAGEKEHVTKSSVGHKNEPKMDNCH SVSRVKTQGQDSLEAQLSSLESSRRVHTSTPSDKNLLDTYNTELLKSDSDNNNSDDCGNILPSDIMDFVLKNTPSMQALGESPESSSSEL LNLGEGLGLDSNREKDMGLFEVFSQQLPTTEPVDSSVSSSISAEEQFELPLELPSDLSVLTTRSPTVPSQNPSRLAVISDSGEKRVTITE KSVASSESDPALLSPGVDPTPEGHMTPDHFIQGHMDADHISSPPCGSVEQGHGNNQDLTRNSSTPGLQVPVSPTVPIQNQKYVPNSTDSP GPSQISNAAVQTTPPHLKPATEKLIVVNQNMQPLYVLQTLPNGVTQKIQLTSSVSSTPSVMETNTSVLGPMGGGLTLTTGLNPSLPTSQS LFPSASKGLLPMSHHQHLHSFPAATQSSFPPNISNPPSGLLIGVQPPPDPQLLVSESSQRTDLSTTVATPSSGLKKRPISRLQTRKNKKL APSSTPSNIAPSDVVSNMTLINFTPSQLPNHPSLLDLGSLNTSSHRTVPNIIKRSKSSIMYFEPAPLLPQSVGGTAATAAGTSTISQDTS HLTSGSVSGLASSSSVLNVVSMQTTTTPTSSASVPGHVTLTNPRLLGTPDIGSISNLLIKASQQSLGIQDQPVALPPSSGMFPQLGTSQT PSTAAITAASSICVLPSTQTTGITAASPSGEADEHYQLQHVNQLLASKTGIHSSQRDLDSASGPQVSNFTQTVDAPNSMGLEQNKALSSA VQASPTSPGGSPSSPSSGQRSASPSVPGPTKPKPKTKRFQLPLDKGNGKKHKVSHLRTSSSEAHIPDQETTSLTSGTGTPGAEAEQQDTA SVEQSSQKECGQPAGQVAVLPEVQVTQNPANEQESAEPKTVEEEESNFSSPLMLWLQQEQKRKESITEKKPKKGLVFEISSDDGFQICAE SIEDAWKSLTDKVQEARSNARLKQLSFAGVNGLRMLGILHDAVVFLIEQLSGAKHCRNYKFRFHKPEEANEPPLNPHGSARAEVHLRKSA FDMFNFLASKHRQPPEYNPNDEEEEEVQLKSARRATSMDLPMPMRFRHLKKTSKEAVGVYRSPIHGRGLFCKRNIDAGEMVIEYAGNVIR SIQTDKREKYYDSKGIGCYMFRIDDSEVVDATMHGNAARFINHSCEPNCYSRVINIDGQKHIVIFAMRKIYRGEELTYDYKFPIEDASNK -------------------------------------------------------------- >2660_2660_8_AFF1-KMT2A_AFF1_chr4_87967438_ENST00000395146_KMT2A_chr11_118354897_ENST00000389506_length(amino acids)=2663AA_BP=56 METMAFTERVNSSGNSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKEKPPPVNKQENAGTLNILSTLSNGNSSKQKIPAD GVHRIRVDFKEDCEAENVWEMGGLGILTSVPITPRVVCFLCASSGHVEFVYCQVCCEPFHKFCLEENERPLEDQLENWCCRRCKFCHVCG RQHQATKQLLECNKCRNSYHPECLGPNYPTKPTKKKKVWICTKCVRCKSCGSTTPGKGWDAQWSHDFSLCHDCAKLFAKGNFCPLCDKCY DDDDYESKMMQCGKCDRWVHSKCENLSDEMYEILSNLPESVAYTCVNCTERHPAEWRLALEKELQISLKQVLTALLNSRTTSHLLRYRQA AKPPDLNPETEESIPSRSSPEGPDPPVLTEVSKQDDQQPLDLEGVKRKMDQGNYTSVLEFSDDIVKIIQAAINSDGGQPEIKKANSMVKS FFIRQMERVFPWFSVKKSRFWEPNKVSSNSGMLPNAVLPPSLDHNYAQWQEREENSHTEQPPLMKKIIPAPKPKGPGEPDSPTPLHPPTP PILSTDRSREDSPELNPPPGIEDNRQCALCLTYGDDSANDAGRLLYIGQNEWTHVNCALWSAEVFEDDDGSLKNVHMAVIRGKQLRCEFC QKPGATVGCCLTSCTSNYHFMCSRAKNCVFLDDKKVYCQRHRDLIKGEVVPENGFEVFRRVFVDFEGISLRRKFLNGLEPENIHMMIGSM TIDCLGILNDLSDCEDKLFPIGYQCSRVYWSTTDARKRCVYTCKIVECRPPVVEPDINSTVEHDENRTIAHSPTSFTESSSKESQNTAEI ISPPSPDRPPHSQTSGSCYYHVISKVPRIRTPSYSPTQRSPGCRPLPSAGSPTPTTHEIVTVGDPLLSSGLRSIGSRRHSTSSLSPQRSK LRIMSPMRTGNTYSRNNVSSVSTTGTATDLESSAKVVDHVLGPLNSSTSLGQNTSTSSNLQRTVVTVGNKNSHLDGSSSSEMKQSSASDL VSKSSSLKGEKTKVLSSKSSEGSAHNVAYPGIPKLAPQVHNTTSRELNVSKIGSFAEPSSVSFSSKEALSFPHLHLRGQRNDRDQHTDST QSANSSPDEDTEVKTLKLSGMSNRSSIINEHMGSSSRDRRQKGKKSCKETFKEKHSSKSFLEPGQVTTGEEGNLKPEFMDEVLTPEYMGQ RPCNNVSSDKIGDKGLSMPGVPKAPPMQVEGSAKELQAPRKRTVKVTLTPLKMENESQSKNALKESSPASPLQIESTSPTEPISASENPG DGPVAQPSPNNTSCQDSQSNNYQNLPVQDRNLMLPDGPKPQEDGSFKRRYPRRSARARSNMFFGLTPLYGVRSYGEEDIPFYSSSTGKKR GKRSAEGQVDGADDLSTSDEDDLYYYNFTRTVISSGGEERLASHNLFREEEQCDLPKISQLDGVDDGTESDTSVTATTRKSSQIPKRNGK ENGTENLKIDRPEDAGEKEHVTKSSVGHKNEPKMDNCHSVSRVKTQGQDSLEAQLSSLESSRRVHTSTPSDKNLLDTYNTELLKSDSDNN NSDDCGNILPSDIMDFVLKNTPSMQALGESPESSSSELLNLGEGLGLDSNREKDMGLFEVFSQQLPTTEPVDSSVSSSISAEEQFELPLE LPSDLSVLTTRSPTVPSQNPSRLAVISDSGEKRVTITEKSVASSESDPALLSPGVDPTPEGHMTPDHFIQGHMDADHISSPPCGSVEQGH GNNQDLTRNSSTPGLQVPVSPTVPIQNQKYVPNSTDSPGPSQISNAAVQTTPPHLKPATEKLIVVNQNMQPLYVLQTLPNGVTQKIQLTS SVSSTPSVMETNTSVLGPMGGGLTLTTGLNPSLPTSQSLFPSASKGLLPMSHHQHLHSFPAATQSSFPPNISNPPSGLLIGVQPPPDPQL LVSESSQRTDLSTTVATPSSGLKKRPISRLQTRKNKKLAPSSTPSNIAPSDVVSNMTLINFTPSQLPNHPSLLDLGSLNTSSHRTVPNII KRSKSSIMYFEPAPLLPQSVGGTAATAAGTSTISQDTSHLTSGSVSGLASSSSVLNVVSMQTTTTPTSSASVPGHVTLTNPRLLGTPDIG SISNLLIKASQQSLGIQDQPVALPPSSGMFPQLGTSQTPSTAAITAASSICVLPSTQTTGITAASPSGEADEHYQLQHVNQLLASKTGIH SSQRDLDSASGPQVSNFTQTVDAPNSMGLEQNKALSSAVQASPTSPGGSPSSPSSGQRSASPSVPGPTKPKPKTKRFQLPLDKGNGKKHK VSHLRTSSSEAHIPDQETTSLTSGTGTPGAEAEQQDTASVEQSSQKECGQPAGQVAVLPEVQVTQNPANEQESAEPKTVEEEESNFSSPL MLWLQQEQKRKESITEKKPKKGLVFEISSDDGFQICAESIEDAWKSLTDKVQEARSNARLKQLSFAGVNGLRMLGILHDAVVFLIEQLSG AKHCRNYKFRFHKPEEANEPPLNPHGSARAEVHLRKSAFDMFNFLASKHRQPPEYNPNDEEEEEVQLKSARRATSMDLPMPMRFRHLKKT SKEAVGVYRSPIHGRGLFCKRNIDAGEMVIEYAGNVIRSIQTDKREKYYDSKGIGCYMFRIDDSEVVDATMHGNAARFINHSCEPNCYSR -------------------------------------------------------------- >2660_2660_9_AFF1-KMT2A_AFF1_chr4_87967438_ENST00000395146_KMT2A_chr11_118354897_ENST00000534358_length(amino acids)=2666AA_BP=56 METMAFTERVNSSGNSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKEKPPPVNKQENAGTLNILSTLSNGNSSKQKIPAD GVHRIRVDFKEDCEAENVWEMGGLGILTSVPITPRVVCFLCASSGHVEFVYCQVCCEPFHKFCLEENERPLEDQLENWCCRRCKFCHVCG RQHQATKQLLECNKCRNSYHPECLGPNYPTKPTKKKKVWICTKCVRCKSCGSTTPGKGWDAQWSHDFSLCHDCAKLFAKGNFCPLCDKCY DDDDYESKMMQCGKCDRWVHSKCENLSGTEDEMYEILSNLPESVAYTCVNCTERHPAEWRLALEKELQISLKQVLTALLNSRTTSHLLRY RQAAKPPDLNPETEESIPSRSSPEGPDPPVLTEVSKQDDQQPLDLEGVKRKMDQGNYTSVLEFSDDIVKIIQAAINSDGGQPEIKKANSM VKSFFIRQMERVFPWFSVKKSRFWEPNKVSSNSGMLPNAVLPPSLDHNYAQWQEREENSHTEQPPLMKKIIPAPKPKGPGEPDSPTPLHP PTPPILSTDRSREDSPELNPPPGIEDNRQCALCLTYGDDSANDAGRLLYIGQNEWTHVNCALWSAEVFEDDDGSLKNVHMAVIRGKQLRC EFCQKPGATVGCCLTSCTSNYHFMCSRAKNCVFLDDKKVYCQRHRDLIKGEVVPENGFEVFRRVFVDFEGISLRRKFLNGLEPENIHMMI GSMTIDCLGILNDLSDCEDKLFPIGYQCSRVYWSTTDARKRCVYTCKIVECRPPVVEPDINSTVEHDENRTIAHSPTSFTESSSKESQNT AEIISPPSPDRPPHSQTSGSCYYHVISKVPRIRTPSYSPTQRSPGCRPLPSAGSPTPTTHEIVTVGDPLLSSGLRSIGSRRHSTSSLSPQ RSKLRIMSPMRTGNTYSRNNVSSVSTTGTATDLESSAKVVDHVLGPLNSSTSLGQNTSTSSNLQRTVVTVGNKNSHLDGSSSSEMKQSSA SDLVSKSSSLKGEKTKVLSSKSSEGSAHNVAYPGIPKLAPQVHNTTSRELNVSKIGSFAEPSSVSFSSKEALSFPHLHLRGQRNDRDQHT DSTQSANSSPDEDTEVKTLKLSGMSNRSSIINEHMGSSSRDRRQKGKKSCKETFKEKHSSKSFLEPGQVTTGEEGNLKPEFMDEVLTPEY MGQRPCNNVSSDKIGDKGLSMPGVPKAPPMQVEGSAKELQAPRKRTVKVTLTPLKMENESQSKNALKESSPASPLQIESTSPTEPISASE NPGDGPVAQPSPNNTSCQDSQSNNYQNLPVQDRNLMLPDGPKPQEDGSFKRRYPRRSARARSNMFFGLTPLYGVRSYGEEDIPFYSSSTG KKRGKRSAEGQVDGADDLSTSDEDDLYYYNFTRTVISSGGEERLASHNLFREEEQCDLPKISQLDGVDDGTESDTSVTATTRKSSQIPKR NGKENGTENLKIDRPEDAGEKEHVTKSSVGHKNEPKMDNCHSVSRVKTQGQDSLEAQLSSLESSRRVHTSTPSDKNLLDTYNTELLKSDS DNNNSDDCGNILPSDIMDFVLKNTPSMQALGESPESSSSELLNLGEGLGLDSNREKDMGLFEVFSQQLPTTEPVDSSVSSSISAEEQFEL PLELPSDLSVLTTRSPTVPSQNPSRLAVISDSGEKRVTITEKSVASSESDPALLSPGVDPTPEGHMTPDHFIQGHMDADHISSPPCGSVE QGHGNNQDLTRNSSTPGLQVPVSPTVPIQNQKYVPNSTDSPGPSQISNAAVQTTPPHLKPATEKLIVVNQNMQPLYVLQTLPNGVTQKIQ LTSSVSSTPSVMETNTSVLGPMGGGLTLTTGLNPSLPTSQSLFPSASKGLLPMSHHQHLHSFPAATQSSFPPNISNPPSGLLIGVQPPPD PQLLVSESSQRTDLSTTVATPSSGLKKRPISRLQTRKNKKLAPSSTPSNIAPSDVVSNMTLINFTPSQLPNHPSLLDLGSLNTSSHRTVP NIIKRSKSSIMYFEPAPLLPQSVGGTAATAAGTSTISQDTSHLTSGSVSGLASSSSVLNVVSMQTTTTPTSSASVPGHVTLTNPRLLGTP DIGSISNLLIKASQQSLGIQDQPVALPPSSGMFPQLGTSQTPSTAAITAASSICVLPSTQTTGITAASPSGEADEHYQLQHVNQLLASKT GIHSSQRDLDSASGPQVSNFTQTVDAPNSMGLEQNKALSSAVQASPTSPGGSPSSPSSGQRSASPSVPGPTKPKPKTKRFQLPLDKGNGK KHKVSHLRTSSSEAHIPDQETTSLTSGTGTPGAEAEQQDTASVEQSSQKECGQPAGQVAVLPEVQVTQNPANEQESAEPKTVEEEESNFS SPLMLWLQQEQKRKESITEKKPKKGLVFEISSDDGFQICAESIEDAWKSLTDKVQEARSNARLKQLSFAGVNGLRMLGILHDAVVFLIEQ LSGAKHCRNYKFRFHKPEEANEPPLNPHGSARAEVHLRKSAFDMFNFLASKHRQPPEYNPNDEEEEEVQLKSARRATSMDLPMPMRFRHL KKTSKEAVGVYRSPIHGRGLFCKRNIDAGEMVIEYAGNVIRSIQTDKREKYYDSKGIGCYMFRIDDSEVVDATMHGNAARFINHSCEPNC -------------------------------------------------------------- >2660_2660_10_AFF1-KMT2A_AFF1_chr4_87967438_ENST00000395146_KMT2A_chr11_118359328_ENST00000354520_length(amino acids)=2581AA_BP=56 METMAFTERVNSSGNSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKFVYCQVCCEPFHKFCLEENERPLEDQLENWCCRR CKFCHVCGRQHQATKQLLECNKCRNSYHPECLGPNYPTKPTKKKKVWICTKCVRCKSCGSTTPGKGWDAQWSHDFSLCHDCAKLFAKGNF CPLCDKCYDDDDYESKMMQCGKCDRWVHSKCENLSDEMYEILSNLPESVAYTCVNCTERHPAEWRLALEKELQISLKQVLTALLNSRTTS HLLRYRQAAKPPDLNPETEESIPSRSSPEGPDPPVLTEVSKQDDQQPLDLEGVKRKMDQGNYTSVLEFSDDIVKIIQAAINSDGGQPEIK KANSMVKSFFIRQMERVFPWFSVKKSRFWEPNKVSSNSGMLPNAVLPPSLDHNYAQWQEREENSHTEQPPLMKKIIPAPKPKGPGEPDSP TPLHPPTPPILSTDRSREDSPELNPPPGIEDNRQCALCLTYGDDSANDAGRLLYIGQNEWTHVNCALWSAEVFEDDDGSLKNVHMAVIRG KQLRCEFCQKPGATVGCCLTSCTSNYHFMCSRAKNCVFLDDKKVYCQRHRDLIKGEVVPENGFEVFRRVFVDFEGISLRRKFLNGLEPEN IHMMIGSMTIDCLGILNDLSDCEDKLFPIGYQCSRVYWSTTDARKRCVYTCKIVECRPPVVEPDINSTVEHDENRTIAHSPTSFTESSSK ESQNTAEIISPPSPDRPPHSQTSGSCYYHVISKVPRIRTPSYSPTQRSPGCRPLPSAGSPTPTTHEIVTVGDPLLSSGLRSIGSRRHSTS SLSPQRSKLRIMSPMRTGNTYSRNNVSSVSTTGTATDLESSAKVVDHVLGPLNSSTSLGQNTSTSSNLQRTVVTVGNKNSHLDGSSSSEM KQSSASDLVSKSSSLKGEKTKVLSSKSSEGSAHNVAYPGIPKLAPQVHNTTSRELNVSKIGSFAEPSSVSFSSKEALSFPHLHLRGQRND RDQHTDSTQSANSSPDEDTEVKTLKLSGMSNRSSIINEHMGSSSRDRRQKGKKSCKETFKEKHSSKSFLEPGQVTTGEEGNLKPEFMDEV LTPEYMGQRPCNNVSSDKIGDKGLSMPGVPKAPPMQVEGSAKELQAPRKRTVKVTLTPLKMENESQSKNALKESSPASPLQIESTSPTEP ISASENPGDGPVAQPSPNNTSCQDSQSNNYQNLPVQDRNLMLPDGPKPQEDGSFKRRYPRRSARARSNMFFGLTPLYGVRSYGEEDIPFY SSSTGKKRGKRSAEGQVDGADDLSTSDEDDLYYYNFTRTVISSGGEERLASHNLFREEEQCDLPKISQLDGVDDGTESDTSVTATTRKSS QIPKRNGKENGTENLKIDRPEDAGEKEHVTKSSVGHKNEPKMDNCHSVSRVKTQGQDSLEAQLSSLESSRRVHTSTPSDKNLLDTYNTEL LKSDSDNNNSDDCGNILPSDIMDFVLKNTPSMQALGESPESSSSELLNLGEGLGLDSNREKDMGLFEVFSQQLPTTEPVDSSVSSSISAE EQFELPLELPSDLSVLTTRSPTVPSQNPSRLAVISDSGEKRVTITEKSVASSESDPALLSPGVDPTPEGHMTPDHFIQGHMDADHISSPP CGSVEQGHGNNQDLTRNSSTPGLQVPVSPTVPIQNQKYVPNSTDSPGPSQISNAAVQTTPPHLKPATEKLIVVNQNMQPLYVLQTLPNGV TQKIQLTSSVSSTPSVMETNTSVLGPMGGGLTLTTGLNPSLPTSQSLFPSASKGLLPMSHHQHLHSFPAATQSSFPPNISNPPSGLLIGV QPPPDPQLLVSESSQRTDLSTTVATPSSGLKKRPISRLQTRKNKKLAPSSTPSNIAPSDVVSNMTLINFTPSQLPNHPSLLDLGSLNTSS HRTVPNIIKRSKSSIMYFEPAPLLPQSVGGTAATAAGTSTISQDTSHLTSGSVSGLASSSSVLNVVSMQTTTTPTSSASVPGHVTLTNPR LLGTPDIGSISNLLIKASQQSLGIQDQPVALPPSSGMFPQLGTSQTPSTAAITAASSICVLPSTQTTGITAASPSGEADEHYQLQHVNQL LASKTGIHSSQRDLDSASGPQVSNFTQTVDAPNSMGLEQNKALSSAVQASPTSPGGSPSSPSSGQRSASPSVPGPTKPKPKTKRFQLPLD KGNGKKHKVSHLRTSSSEAHIPDQETTSLTSGTGTPGAEAEQQDTASVEQSSQKECGQPAGQVAVLPEVQVTQNPANEQESAEPKTVEEE ESNFSSPLMLWLQQEQKRKESITEKKPKKGLVFEISSDDGFQICAESIEDAWKSLTDKVQEARSNARLKQLSFAGVNGLRMLGILHDAVV FLIEQLSGAKHCRNYKFRFHKPEEANEPPLNPHGSARAEVHLRKSAFDMFNFLASKHRQPPEYNPNDEEEEEVQLKSARRATSMDLPMPM RFRHLKKTSKEAVGVYRSPIHGRGLFCKRNIDAGEMVIEYAGNVIRSIQTDKREKYYDSKGIGCYMFRIDDSEVVDATMHGNAARFINHS -------------------------------------------------------------- >2660_2660_11_AFF1-KMT2A_AFF1_chr4_87967438_ENST00000395146_KMT2A_chr11_118359328_ENST00000389506_length(amino acids)=2581AA_BP=56 METMAFTERVNSSGNSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKFVYCQVCCEPFHKFCLEENERPLEDQLENWCCRR CKFCHVCGRQHQATKQLLECNKCRNSYHPECLGPNYPTKPTKKKKVWICTKCVRCKSCGSTTPGKGWDAQWSHDFSLCHDCAKLFAKGNF CPLCDKCYDDDDYESKMMQCGKCDRWVHSKCENLSDEMYEILSNLPESVAYTCVNCTERHPAEWRLALEKELQISLKQVLTALLNSRTTS HLLRYRQAAKPPDLNPETEESIPSRSSPEGPDPPVLTEVSKQDDQQPLDLEGVKRKMDQGNYTSVLEFSDDIVKIIQAAINSDGGQPEIK KANSMVKSFFIRQMERVFPWFSVKKSRFWEPNKVSSNSGMLPNAVLPPSLDHNYAQWQEREENSHTEQPPLMKKIIPAPKPKGPGEPDSP TPLHPPTPPILSTDRSREDSPELNPPPGIEDNRQCALCLTYGDDSANDAGRLLYIGQNEWTHVNCALWSAEVFEDDDGSLKNVHMAVIRG KQLRCEFCQKPGATVGCCLTSCTSNYHFMCSRAKNCVFLDDKKVYCQRHRDLIKGEVVPENGFEVFRRVFVDFEGISLRRKFLNGLEPEN IHMMIGSMTIDCLGILNDLSDCEDKLFPIGYQCSRVYWSTTDARKRCVYTCKIVECRPPVVEPDINSTVEHDENRTIAHSPTSFTESSSK ESQNTAEIISPPSPDRPPHSQTSGSCYYHVISKVPRIRTPSYSPTQRSPGCRPLPSAGSPTPTTHEIVTVGDPLLSSGLRSIGSRRHSTS SLSPQRSKLRIMSPMRTGNTYSRNNVSSVSTTGTATDLESSAKVVDHVLGPLNSSTSLGQNTSTSSNLQRTVVTVGNKNSHLDGSSSSEM KQSSASDLVSKSSSLKGEKTKVLSSKSSEGSAHNVAYPGIPKLAPQVHNTTSRELNVSKIGSFAEPSSVSFSSKEALSFPHLHLRGQRND RDQHTDSTQSANSSPDEDTEVKTLKLSGMSNRSSIINEHMGSSSRDRRQKGKKSCKETFKEKHSSKSFLEPGQVTTGEEGNLKPEFMDEV LTPEYMGQRPCNNVSSDKIGDKGLSMPGVPKAPPMQVEGSAKELQAPRKRTVKVTLTPLKMENESQSKNALKESSPASPLQIESTSPTEP ISASENPGDGPVAQPSPNNTSCQDSQSNNYQNLPVQDRNLMLPDGPKPQEDGSFKRRYPRRSARARSNMFFGLTPLYGVRSYGEEDIPFY SSSTGKKRGKRSAEGQVDGADDLSTSDEDDLYYYNFTRTVISSGGEERLASHNLFREEEQCDLPKISQLDGVDDGTESDTSVTATTRKSS QIPKRNGKENGTENLKIDRPEDAGEKEHVTKSSVGHKNEPKMDNCHSVSRVKTQGQDSLEAQLSSLESSRRVHTSTPSDKNLLDTYNTEL LKSDSDNNNSDDCGNILPSDIMDFVLKNTPSMQALGESPESSSSELLNLGEGLGLDSNREKDMGLFEVFSQQLPTTEPVDSSVSSSISAE EQFELPLELPSDLSVLTTRSPTVPSQNPSRLAVISDSGEKRVTITEKSVASSESDPALLSPGVDPTPEGHMTPDHFIQGHMDADHISSPP CGSVEQGHGNNQDLTRNSSTPGLQVPVSPTVPIQNQKYVPNSTDSPGPSQISNAAVQTTPPHLKPATEKLIVVNQNMQPLYVLQTLPNGV TQKIQLTSSVSSTPSVMETNTSVLGPMGGGLTLTTGLNPSLPTSQSLFPSASKGLLPMSHHQHLHSFPAATQSSFPPNISNPPSGLLIGV QPPPDPQLLVSESSQRTDLSTTVATPSSGLKKRPISRLQTRKNKKLAPSSTPSNIAPSDVVSNMTLINFTPSQLPNHPSLLDLGSLNTSS HRTVPNIIKRSKSSIMYFEPAPLLPQSVGGTAATAAGTSTISQDTSHLTSGSVSGLASSSSVLNVVSMQTTTTPTSSASVPGHVTLTNPR LLGTPDIGSISNLLIKASQQSLGIQDQPVALPPSSGMFPQLGTSQTPSTAAITAASSICVLPSTQTTGITAASPSGEADEHYQLQHVNQL LASKTGIHSSQRDLDSASGPQVSNFTQTVDAPNSMGLEQNKALSSAVQASPTSPGGSPSSPSSGQRSASPSVPGPTKPKPKTKRFQLPLD KGNGKKHKVSHLRTSSSEAHIPDQETTSLTSGTGTPGAEAEQQDTASVEQSSQKECGQPAGQVAVLPEVQVTQNPANEQESAEPKTVEEE ESNFSSPLMLWLQQEQKRKESITEKKPKKGLVFEISSDDGFQICAESIEDAWKSLTDKVQEARSNARLKQLSFAGVNGLRMLGILHDAVV FLIEQLSGAKHCRNYKFRFHKPEEANEPPLNPHGSARAEVHLRKSAFDMFNFLASKHRQPPEYNPNDEEEEEVQLKSARRATSMDLPMPM RFRHLKKTSKEAVGVYRSPIHGRGLFCKRNIDAGEMVIEYAGNVIRSIQTDKREKYYDSKGIGCYMFRIDDSEVVDATMHGNAARFINHS -------------------------------------------------------------- >2660_2660_12_AFF1-KMT2A_AFF1_chr4_87967438_ENST00000395146_KMT2A_chr11_118359328_ENST00000534358_length(amino acids)=2584AA_BP=56 METMAFTERVNSSGNSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKFVYCQVCCEPFHKFCLEENERPLEDQLENWCCRR CKFCHVCGRQHQATKQLLECNKCRNSYHPECLGPNYPTKPTKKKKVWICTKCVRCKSCGSTTPGKGWDAQWSHDFSLCHDCAKLFAKGNF CPLCDKCYDDDDYESKMMQCGKCDRWVHSKCENLSGTEDEMYEILSNLPESVAYTCVNCTERHPAEWRLALEKELQISLKQVLTALLNSR TTSHLLRYRQAAKPPDLNPETEESIPSRSSPEGPDPPVLTEVSKQDDQQPLDLEGVKRKMDQGNYTSVLEFSDDIVKIIQAAINSDGGQP EIKKANSMVKSFFIRQMERVFPWFSVKKSRFWEPNKVSSNSGMLPNAVLPPSLDHNYAQWQEREENSHTEQPPLMKKIIPAPKPKGPGEP DSPTPLHPPTPPILSTDRSREDSPELNPPPGIEDNRQCALCLTYGDDSANDAGRLLYIGQNEWTHVNCALWSAEVFEDDDGSLKNVHMAV IRGKQLRCEFCQKPGATVGCCLTSCTSNYHFMCSRAKNCVFLDDKKVYCQRHRDLIKGEVVPENGFEVFRRVFVDFEGISLRRKFLNGLE PENIHMMIGSMTIDCLGILNDLSDCEDKLFPIGYQCSRVYWSTTDARKRCVYTCKIVECRPPVVEPDINSTVEHDENRTIAHSPTSFTES SSKESQNTAEIISPPSPDRPPHSQTSGSCYYHVISKVPRIRTPSYSPTQRSPGCRPLPSAGSPTPTTHEIVTVGDPLLSSGLRSIGSRRH STSSLSPQRSKLRIMSPMRTGNTYSRNNVSSVSTTGTATDLESSAKVVDHVLGPLNSSTSLGQNTSTSSNLQRTVVTVGNKNSHLDGSSS SEMKQSSASDLVSKSSSLKGEKTKVLSSKSSEGSAHNVAYPGIPKLAPQVHNTTSRELNVSKIGSFAEPSSVSFSSKEALSFPHLHLRGQ RNDRDQHTDSTQSANSSPDEDTEVKTLKLSGMSNRSSIINEHMGSSSRDRRQKGKKSCKETFKEKHSSKSFLEPGQVTTGEEGNLKPEFM DEVLTPEYMGQRPCNNVSSDKIGDKGLSMPGVPKAPPMQVEGSAKELQAPRKRTVKVTLTPLKMENESQSKNALKESSPASPLQIESTSP TEPISASENPGDGPVAQPSPNNTSCQDSQSNNYQNLPVQDRNLMLPDGPKPQEDGSFKRRYPRRSARARSNMFFGLTPLYGVRSYGEEDI PFYSSSTGKKRGKRSAEGQVDGADDLSTSDEDDLYYYNFTRTVISSGGEERLASHNLFREEEQCDLPKISQLDGVDDGTESDTSVTATTR KSSQIPKRNGKENGTENLKIDRPEDAGEKEHVTKSSVGHKNEPKMDNCHSVSRVKTQGQDSLEAQLSSLESSRRVHTSTPSDKNLLDTYN TELLKSDSDNNNSDDCGNILPSDIMDFVLKNTPSMQALGESPESSSSELLNLGEGLGLDSNREKDMGLFEVFSQQLPTTEPVDSSVSSSI SAEEQFELPLELPSDLSVLTTRSPTVPSQNPSRLAVISDSGEKRVTITEKSVASSESDPALLSPGVDPTPEGHMTPDHFIQGHMDADHIS SPPCGSVEQGHGNNQDLTRNSSTPGLQVPVSPTVPIQNQKYVPNSTDSPGPSQISNAAVQTTPPHLKPATEKLIVVNQNMQPLYVLQTLP NGVTQKIQLTSSVSSTPSVMETNTSVLGPMGGGLTLTTGLNPSLPTSQSLFPSASKGLLPMSHHQHLHSFPAATQSSFPPNISNPPSGLL IGVQPPPDPQLLVSESSQRTDLSTTVATPSSGLKKRPISRLQTRKNKKLAPSSTPSNIAPSDVVSNMTLINFTPSQLPNHPSLLDLGSLN TSSHRTVPNIIKRSKSSIMYFEPAPLLPQSVGGTAATAAGTSTISQDTSHLTSGSVSGLASSSSVLNVVSMQTTTTPTSSASVPGHVTLT NPRLLGTPDIGSISNLLIKASQQSLGIQDQPVALPPSSGMFPQLGTSQTPSTAAITAASSICVLPSTQTTGITAASPSGEADEHYQLQHV NQLLASKTGIHSSQRDLDSASGPQVSNFTQTVDAPNSMGLEQNKALSSAVQASPTSPGGSPSSPSSGQRSASPSVPGPTKPKPKTKRFQL PLDKGNGKKHKVSHLRTSSSEAHIPDQETTSLTSGTGTPGAEAEQQDTASVEQSSQKECGQPAGQVAVLPEVQVTQNPANEQESAEPKTV EEEESNFSSPLMLWLQQEQKRKESITEKKPKKGLVFEISSDDGFQICAESIEDAWKSLTDKVQEARSNARLKQLSFAGVNGLRMLGILHD AVVFLIEQLSGAKHCRNYKFRFHKPEEANEPPLNPHGSARAEVHLRKSAFDMFNFLASKHRQPPEYNPNDEEEEEVQLKSARRATSMDLP MPMRFRHLKKTSKEAVGVYRSPIHGRGLFCKRNIDAGEMVIEYAGNVIRSIQTDKREKYYDSKGIGCYMFRIDDSEVVDATMHGNAARFI -------------------------------------------------------------- >2660_2660_13_AFF1-KMT2A_AFF1_chr4_87968746_ENST00000307808_KMT2A_chr11_118354897_ENST00000354520_length(amino acids)=2915AA_BP=346 MAAQSSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKTAKGDELSSRIQNMLGNYEEVKEFLSTKSHTHRLDASENRLGKP KYPLIPDKGSSIPSSSFHTSVHHQSIHTPASGPLSVGNISHNPKMAQPRTEPMPSLHAKSCGPPDSQHLTQDRLGQEGFGSSHHKKGDRR ADGDHCASVTDSAPERELSPLISLPSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNNSKGYCPAKSPKDLAVKVHDKETPQDSLVAPAQPP SQTFPPPSLPSKSVAMQQKPTAYVRPMDGQDQAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEEKPPPVNKQENAGT LNILSTLSNGNSSKQKIPADGVHRIRVDFKFVYCQVCCEPFHKFCLEENERPLEDQLENWCCRRCKFCHVCGRQHQATKQLLECNKCRNS YHPECLGPNYPTKPTKKKKVWICTKCVRCKSCGSTTPGKGWDAQWSHDFSLCHDCAKLFAKGNFCPLCDKCYDDDDYESKMMQCGKCDRW VHSKCENLSDEMYEILSNLPESVAYTCVNCTERHPAEWRLALEKELQISLKQVLTALLNSRTTSHLLRYRQAAKPPDLNPETEESIPSRS SPEGPDPPVLTEVSKQDDQQPLDLEGVKRKMDQGNYTSVLEFSDDIVKIIQAAINSDGGQPEIKKANSMVKSFFIRQMERVFPWFSVKKS RFWEPNKVSSNSGMLPNAVLPPSLDHNYAQWQEREENSHTEQPPLMKKIIPAPKPKGPGEPDSPTPLHPPTPPILSTDRSREDSPELNPP PGIEDNRQCALCLTYGDDSANDAGRLLYIGQNEWTHVNCALWSAEVFEDDDGSLKNVHMAVIRGKQLRCEFCQKPGATVGCCLTSCTSNY HFMCSRAKNCVFLDDKKVYCQRHRDLIKGEVVPENGFEVFRRVFVDFEGISLRRKFLNGLEPENIHMMIGSMTIDCLGILNDLSDCEDKL FPIGYQCSRVYWSTTDARKRCVYTCKIVECRPPVVEPDINSTVEHDENRTIAHSPTSFTESSSKESQNTAEIISPPSPDRPPHSQTSGSC YYHVISKVPRIRTPSYSPTQRSPGCRPLPSAGSPTPTTHEIVTVGDPLLSSGLRSIGSRRHSTSSLSPQRSKLRIMSPMRTGNTYSRNNV SSVSTTGTATDLESSAKVVDHVLGPLNSSTSLGQNTSTSSNLQRTVVTVGNKNSHLDGSSSSEMKQSSASDLVSKSSSLKGEKTKVLSSK SSEGSAHNVAYPGIPKLAPQVHNTTSRELNVSKIGSFAEPSSVSFSSKEALSFPHLHLRGQRNDRDQHTDSTQSANSSPDEDTEVKTLKL SGMSNRSSIINEHMGSSSRDRRQKGKKSCKETFKEKHSSKSFLEPGQVTTGEEGNLKPEFMDEVLTPEYMGQRPCNNVSSDKIGDKGLSM PGVPKAPPMQVEGSAKELQAPRKRTVKVTLTPLKMENESQSKNALKESSPASPLQIESTSPTEPISASENPGDGPVAQPSPNNTSCQDSQ SNNYQNLPVQDRNLMLPDGPKPQEDGSFKRRYPRRSARARSNMFFGLTPLYGVRSYGEEDIPFYSSSTGKKRGKRSAEGQVDGADDLSTS DEDDLYYYNFTRTVISSGGEERLASHNLFREEEQCDLPKISQLDGVDDGTESDTSVTATTRKSSQIPKRNGKENGTENLKIDRPEDAGEK EHVTKSSVGHKNEPKMDNCHSVSRVKTQGQDSLEAQLSSLESSRRVHTSTPSDKNLLDTYNTELLKSDSDNNNSDDCGNILPSDIMDFVL KNTPSMQALGESPESSSSELLNLGEGLGLDSNREKDMGLFEVFSQQLPTTEPVDSSVSSSISAEEQFELPLELPSDLSVLTTRSPTVPSQ NPSRLAVISDSGEKRVTITEKSVASSESDPALLSPGVDPTPEGHMTPDHFIQGHMDADHISSPPCGSVEQGHGNNQDLTRNSSTPGLQVP VSPTVPIQNQKYVPNSTDSPGPSQISNAAVQTTPPHLKPATEKLIVVNQNMQPLYVLQTLPNGVTQKIQLTSSVSSTPSVMETNTSVLGP MGGGLTLTTGLNPSLPTSQSLFPSASKGLLPMSHHQHLHSFPAATQSSFPPNISNPPSGLLIGVQPPPDPQLLVSESSQRTDLSTTVATP SSGLKKRPISRLQTRKNKKLAPSSTPSNIAPSDVVSNMTLINFTPSQLPNHPSLLDLGSLNTSSHRTVPNIIKRSKSSIMYFEPAPLLPQ SVGGTAATAAGTSTISQDTSHLTSGSVSGLASSSSVLNVVSMQTTTTPTSSASVPGHVTLTNPRLLGTPDIGSISNLLIKASQQSLGIQD QPVALPPSSGMFPQLGTSQTPSTAAITAASSICVLPSTQTTGITAASPSGEADEHYQLQHVNQLLASKTGIHSSQRDLDSASGPQVSNFT QTVDAPNSMGLEQNKALSSAVQASPTSPGGSPSSPSSGQRSASPSVPGPTKPKPKTKRFQLPLDKGNGKKHKVSHLRTSSSEAHIPDQET TSLTSGTGTPGAEAEQQDTASVEQSSQKECGQPAGQVAVLPEVQVTQNPANEQESAEPKTVEEEESNFSSPLMLWLQQEQKRKESITEKK PKKGLVFEISSDDGFQICAESIEDAWKSLTDKVQEARSNARLKQLSFAGVNGLRMLGILHDAVVFLIEQLSGAKHCRNYKFRFHKPEEAN EPPLNPHGSARAEVHLRKSAFDMFNFLASKHRQPPEYNPNDEEEEEVQLKSARRATSMDLPMPMRFRHLKKTSKEAVGVYRSPIHGRGLF CKRNIDAGEMVIEYAGNVIRSIQTDKREKYYDSKGIGCYMFRIDDSEVVDATMHGNAARFINHSCEPNCYSRVINIDGQKHIVIFAMRKI -------------------------------------------------------------- >2660_2660_14_AFF1-KMT2A_AFF1_chr4_87968746_ENST00000307808_KMT2A_chr11_118354897_ENST00000389506_length(amino acids)=2953AA_BP=346 MAAQSSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKTAKGDELSSRIQNMLGNYEEVKEFLSTKSHTHRLDASENRLGKP KYPLIPDKGSSIPSSSFHTSVHHQSIHTPASGPLSVGNISHNPKMAQPRTEPMPSLHAKSCGPPDSQHLTQDRLGQEGFGSSHHKKGDRR ADGDHCASVTDSAPERELSPLISLPSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNNSKGYCPAKSPKDLAVKVHDKETPQDSLVAPAQPP SQTFPPPSLPSKSVAMQQKPTAYVRPMDGQDQAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEEKPPPVNKQENAGT LNILSTLSNGNSSKQKIPADGVHRIRVDFKEDCEAENVWEMGGLGILTSVPITPRVVCFLCASSGHVEFVYCQVCCEPFHKFCLEENERP LEDQLENWCCRRCKFCHVCGRQHQATKQLLECNKCRNSYHPECLGPNYPTKPTKKKKVWICTKCVRCKSCGSTTPGKGWDAQWSHDFSLC HDCAKLFAKGNFCPLCDKCYDDDDYESKMMQCGKCDRWVHSKCENLSDEMYEILSNLPESVAYTCVNCTERHPAEWRLALEKELQISLKQ VLTALLNSRTTSHLLRYRQAAKPPDLNPETEESIPSRSSPEGPDPPVLTEVSKQDDQQPLDLEGVKRKMDQGNYTSVLEFSDDIVKIIQA AINSDGGQPEIKKANSMVKSFFIRQMERVFPWFSVKKSRFWEPNKVSSNSGMLPNAVLPPSLDHNYAQWQEREENSHTEQPPLMKKIIPA PKPKGPGEPDSPTPLHPPTPPILSTDRSREDSPELNPPPGIEDNRQCALCLTYGDDSANDAGRLLYIGQNEWTHVNCALWSAEVFEDDDG SLKNVHMAVIRGKQLRCEFCQKPGATVGCCLTSCTSNYHFMCSRAKNCVFLDDKKVYCQRHRDLIKGEVVPENGFEVFRRVFVDFEGISL RRKFLNGLEPENIHMMIGSMTIDCLGILNDLSDCEDKLFPIGYQCSRVYWSTTDARKRCVYTCKIVECRPPVVEPDINSTVEHDENRTIA HSPTSFTESSSKESQNTAEIISPPSPDRPPHSQTSGSCYYHVISKVPRIRTPSYSPTQRSPGCRPLPSAGSPTPTTHEIVTVGDPLLSSG LRSIGSRRHSTSSLSPQRSKLRIMSPMRTGNTYSRNNVSSVSTTGTATDLESSAKVVDHVLGPLNSSTSLGQNTSTSSNLQRTVVTVGNK NSHLDGSSSSEMKQSSASDLVSKSSSLKGEKTKVLSSKSSEGSAHNVAYPGIPKLAPQVHNTTSRELNVSKIGSFAEPSSVSFSSKEALS FPHLHLRGQRNDRDQHTDSTQSANSSPDEDTEVKTLKLSGMSNRSSIINEHMGSSSRDRRQKGKKSCKETFKEKHSSKSFLEPGQVTTGE EGNLKPEFMDEVLTPEYMGQRPCNNVSSDKIGDKGLSMPGVPKAPPMQVEGSAKELQAPRKRTVKVTLTPLKMENESQSKNALKESSPAS PLQIESTSPTEPISASENPGDGPVAQPSPNNTSCQDSQSNNYQNLPVQDRNLMLPDGPKPQEDGSFKRRYPRRSARARSNMFFGLTPLYG VRSYGEEDIPFYSSSTGKKRGKRSAEGQVDGADDLSTSDEDDLYYYNFTRTVISSGGEERLASHNLFREEEQCDLPKISQLDGVDDGTES DTSVTATTRKSSQIPKRNGKENGTENLKIDRPEDAGEKEHVTKSSVGHKNEPKMDNCHSVSRVKTQGQDSLEAQLSSLESSRRVHTSTPS DKNLLDTYNTELLKSDSDNNNSDDCGNILPSDIMDFVLKNTPSMQALGESPESSSSELLNLGEGLGLDSNREKDMGLFEVFSQQLPTTEP VDSSVSSSISAEEQFELPLELPSDLSVLTTRSPTVPSQNPSRLAVISDSGEKRVTITEKSVASSESDPALLSPGVDPTPEGHMTPDHFIQ GHMDADHISSPPCGSVEQGHGNNQDLTRNSSTPGLQVPVSPTVPIQNQKYVPNSTDSPGPSQISNAAVQTTPPHLKPATEKLIVVNQNMQ PLYVLQTLPNGVTQKIQLTSSVSSTPSVMETNTSVLGPMGGGLTLTTGLNPSLPTSQSLFPSASKGLLPMSHHQHLHSFPAATQSSFPPN ISNPPSGLLIGVQPPPDPQLLVSESSQRTDLSTTVATPSSGLKKRPISRLQTRKNKKLAPSSTPSNIAPSDVVSNMTLINFTPSQLPNHP SLLDLGSLNTSSHRTVPNIIKRSKSSIMYFEPAPLLPQSVGGTAATAAGTSTISQDTSHLTSGSVSGLASSSSVLNVVSMQTTTTPTSSA SVPGHVTLTNPRLLGTPDIGSISNLLIKASQQSLGIQDQPVALPPSSGMFPQLGTSQTPSTAAITAASSICVLPSTQTTGITAASPSGEA DEHYQLQHVNQLLASKTGIHSSQRDLDSASGPQVSNFTQTVDAPNSMGLEQNKALSSAVQASPTSPGGSPSSPSSGQRSASPSVPGPTKP KPKTKRFQLPLDKGNGKKHKVSHLRTSSSEAHIPDQETTSLTSGTGTPGAEAEQQDTASVEQSSQKECGQPAGQVAVLPEVQVTQNPANE QESAEPKTVEEEESNFSSPLMLWLQQEQKRKESITEKKPKKGLVFEISSDDGFQICAESIEDAWKSLTDKVQEARSNARLKQLSFAGVNG LRMLGILHDAVVFLIEQLSGAKHCRNYKFRFHKPEEANEPPLNPHGSARAEVHLRKSAFDMFNFLASKHRQPPEYNPNDEEEEEVQLKSA RRATSMDLPMPMRFRHLKKTSKEAVGVYRSPIHGRGLFCKRNIDAGEMVIEYAGNVIRSIQTDKREKYYDSKGIGCYMFRIDDSEVVDAT -------------------------------------------------------------- >2660_2660_15_AFF1-KMT2A_AFF1_chr4_87968746_ENST00000307808_KMT2A_chr11_118354897_ENST00000534358_length(amino acids)=2956AA_BP=346 MAAQSSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKTAKGDELSSRIQNMLGNYEEVKEFLSTKSHTHRLDASENRLGKP KYPLIPDKGSSIPSSSFHTSVHHQSIHTPASGPLSVGNISHNPKMAQPRTEPMPSLHAKSCGPPDSQHLTQDRLGQEGFGSSHHKKGDRR ADGDHCASVTDSAPERELSPLISLPSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNNSKGYCPAKSPKDLAVKVHDKETPQDSLVAPAQPP SQTFPPPSLPSKSVAMQQKPTAYVRPMDGQDQAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEEKPPPVNKQENAGT LNILSTLSNGNSSKQKIPADGVHRIRVDFKEDCEAENVWEMGGLGILTSVPITPRVVCFLCASSGHVEFVYCQVCCEPFHKFCLEENERP LEDQLENWCCRRCKFCHVCGRQHQATKQLLECNKCRNSYHPECLGPNYPTKPTKKKKVWICTKCVRCKSCGSTTPGKGWDAQWSHDFSLC HDCAKLFAKGNFCPLCDKCYDDDDYESKMMQCGKCDRWVHSKCENLSGTEDEMYEILSNLPESVAYTCVNCTERHPAEWRLALEKELQIS LKQVLTALLNSRTTSHLLRYRQAAKPPDLNPETEESIPSRSSPEGPDPPVLTEVSKQDDQQPLDLEGVKRKMDQGNYTSVLEFSDDIVKI IQAAINSDGGQPEIKKANSMVKSFFIRQMERVFPWFSVKKSRFWEPNKVSSNSGMLPNAVLPPSLDHNYAQWQEREENSHTEQPPLMKKI IPAPKPKGPGEPDSPTPLHPPTPPILSTDRSREDSPELNPPPGIEDNRQCALCLTYGDDSANDAGRLLYIGQNEWTHVNCALWSAEVFED DDGSLKNVHMAVIRGKQLRCEFCQKPGATVGCCLTSCTSNYHFMCSRAKNCVFLDDKKVYCQRHRDLIKGEVVPENGFEVFRRVFVDFEG ISLRRKFLNGLEPENIHMMIGSMTIDCLGILNDLSDCEDKLFPIGYQCSRVYWSTTDARKRCVYTCKIVECRPPVVEPDINSTVEHDENR TIAHSPTSFTESSSKESQNTAEIISPPSPDRPPHSQTSGSCYYHVISKVPRIRTPSYSPTQRSPGCRPLPSAGSPTPTTHEIVTVGDPLL SSGLRSIGSRRHSTSSLSPQRSKLRIMSPMRTGNTYSRNNVSSVSTTGTATDLESSAKVVDHVLGPLNSSTSLGQNTSTSSNLQRTVVTV GNKNSHLDGSSSSEMKQSSASDLVSKSSSLKGEKTKVLSSKSSEGSAHNVAYPGIPKLAPQVHNTTSRELNVSKIGSFAEPSSVSFSSKE ALSFPHLHLRGQRNDRDQHTDSTQSANSSPDEDTEVKTLKLSGMSNRSSIINEHMGSSSRDRRQKGKKSCKETFKEKHSSKSFLEPGQVT TGEEGNLKPEFMDEVLTPEYMGQRPCNNVSSDKIGDKGLSMPGVPKAPPMQVEGSAKELQAPRKRTVKVTLTPLKMENESQSKNALKESS PASPLQIESTSPTEPISASENPGDGPVAQPSPNNTSCQDSQSNNYQNLPVQDRNLMLPDGPKPQEDGSFKRRYPRRSARARSNMFFGLTP LYGVRSYGEEDIPFYSSSTGKKRGKRSAEGQVDGADDLSTSDEDDLYYYNFTRTVISSGGEERLASHNLFREEEQCDLPKISQLDGVDDG TESDTSVTATTRKSSQIPKRNGKENGTENLKIDRPEDAGEKEHVTKSSVGHKNEPKMDNCHSVSRVKTQGQDSLEAQLSSLESSRRVHTS TPSDKNLLDTYNTELLKSDSDNNNSDDCGNILPSDIMDFVLKNTPSMQALGESPESSSSELLNLGEGLGLDSNREKDMGLFEVFSQQLPT TEPVDSSVSSSISAEEQFELPLELPSDLSVLTTRSPTVPSQNPSRLAVISDSGEKRVTITEKSVASSESDPALLSPGVDPTPEGHMTPDH FIQGHMDADHISSPPCGSVEQGHGNNQDLTRNSSTPGLQVPVSPTVPIQNQKYVPNSTDSPGPSQISNAAVQTTPPHLKPATEKLIVVNQ NMQPLYVLQTLPNGVTQKIQLTSSVSSTPSVMETNTSVLGPMGGGLTLTTGLNPSLPTSQSLFPSASKGLLPMSHHQHLHSFPAATQSSF PPNISNPPSGLLIGVQPPPDPQLLVSESSQRTDLSTTVATPSSGLKKRPISRLQTRKNKKLAPSSTPSNIAPSDVVSNMTLINFTPSQLP NHPSLLDLGSLNTSSHRTVPNIIKRSKSSIMYFEPAPLLPQSVGGTAATAAGTSTISQDTSHLTSGSVSGLASSSSVLNVVSMQTTTTPT SSASVPGHVTLTNPRLLGTPDIGSISNLLIKASQQSLGIQDQPVALPPSSGMFPQLGTSQTPSTAAITAASSICVLPSTQTTGITAASPS GEADEHYQLQHVNQLLASKTGIHSSQRDLDSASGPQVSNFTQTVDAPNSMGLEQNKALSSAVQASPTSPGGSPSSPSSGQRSASPSVPGP TKPKPKTKRFQLPLDKGNGKKHKVSHLRTSSSEAHIPDQETTSLTSGTGTPGAEAEQQDTASVEQSSQKECGQPAGQVAVLPEVQVTQNP ANEQESAEPKTVEEEESNFSSPLMLWLQQEQKRKESITEKKPKKGLVFEISSDDGFQICAESIEDAWKSLTDKVQEARSNARLKQLSFAG VNGLRMLGILHDAVVFLIEQLSGAKHCRNYKFRFHKPEEANEPPLNPHGSARAEVHLRKSAFDMFNFLASKHRQPPEYNPNDEEEEEVQL KSARRATSMDLPMPMRFRHLKKTSKEAVGVYRSPIHGRGLFCKRNIDAGEMVIEYAGNVIRSIQTDKREKYYDSKGIGCYMFRIDDSEVV -------------------------------------------------------------- >2660_2660_16_AFF1-KMT2A_AFF1_chr4_87968746_ENST00000395146_KMT2A_chr11_118354897_ENST00000354520_length(amino acids)=2925AA_BP=356 METMAFTERVNSSGNSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKTAKGDELSSRIQNMLGNYEEVKEFLSTKSHTHRL DASENRLGKPKYPLIPDKGSSIPSSSFHTSVHHQSIHTPASGPLSVGNISHNPKMAQPRTEPMPSLHAKSCGPPDSQHLTQDRLGQEGFG SSHHKKGDRRADGDHCASVTDSAPERELSPLISLPSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNNSKGYCPAKSPKDLAVKVHDKETPQ DSLVAPAQPPSQTFPPPSLPSKSVAMQQKPTAYVRPMDGQDQAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEEKPP PVNKQENAGTLNILSTLSNGNSSKQKIPADGVHRIRVDFKFVYCQVCCEPFHKFCLEENERPLEDQLENWCCRRCKFCHVCGRQHQATKQ LLECNKCRNSYHPECLGPNYPTKPTKKKKVWICTKCVRCKSCGSTTPGKGWDAQWSHDFSLCHDCAKLFAKGNFCPLCDKCYDDDDYESK MMQCGKCDRWVHSKCENLSDEMYEILSNLPESVAYTCVNCTERHPAEWRLALEKELQISLKQVLTALLNSRTTSHLLRYRQAAKPPDLNP ETEESIPSRSSPEGPDPPVLTEVSKQDDQQPLDLEGVKRKMDQGNYTSVLEFSDDIVKIIQAAINSDGGQPEIKKANSMVKSFFIRQMER VFPWFSVKKSRFWEPNKVSSNSGMLPNAVLPPSLDHNYAQWQEREENSHTEQPPLMKKIIPAPKPKGPGEPDSPTPLHPPTPPILSTDRS REDSPELNPPPGIEDNRQCALCLTYGDDSANDAGRLLYIGQNEWTHVNCALWSAEVFEDDDGSLKNVHMAVIRGKQLRCEFCQKPGATVG CCLTSCTSNYHFMCSRAKNCVFLDDKKVYCQRHRDLIKGEVVPENGFEVFRRVFVDFEGISLRRKFLNGLEPENIHMMIGSMTIDCLGIL NDLSDCEDKLFPIGYQCSRVYWSTTDARKRCVYTCKIVECRPPVVEPDINSTVEHDENRTIAHSPTSFTESSSKESQNTAEIISPPSPDR PPHSQTSGSCYYHVISKVPRIRTPSYSPTQRSPGCRPLPSAGSPTPTTHEIVTVGDPLLSSGLRSIGSRRHSTSSLSPQRSKLRIMSPMR TGNTYSRNNVSSVSTTGTATDLESSAKVVDHVLGPLNSSTSLGQNTSTSSNLQRTVVTVGNKNSHLDGSSSSEMKQSSASDLVSKSSSLK GEKTKVLSSKSSEGSAHNVAYPGIPKLAPQVHNTTSRELNVSKIGSFAEPSSVSFSSKEALSFPHLHLRGQRNDRDQHTDSTQSANSSPD EDTEVKTLKLSGMSNRSSIINEHMGSSSRDRRQKGKKSCKETFKEKHSSKSFLEPGQVTTGEEGNLKPEFMDEVLTPEYMGQRPCNNVSS DKIGDKGLSMPGVPKAPPMQVEGSAKELQAPRKRTVKVTLTPLKMENESQSKNALKESSPASPLQIESTSPTEPISASENPGDGPVAQPS PNNTSCQDSQSNNYQNLPVQDRNLMLPDGPKPQEDGSFKRRYPRRSARARSNMFFGLTPLYGVRSYGEEDIPFYSSSTGKKRGKRSAEGQ VDGADDLSTSDEDDLYYYNFTRTVISSGGEERLASHNLFREEEQCDLPKISQLDGVDDGTESDTSVTATTRKSSQIPKRNGKENGTENLK IDRPEDAGEKEHVTKSSVGHKNEPKMDNCHSVSRVKTQGQDSLEAQLSSLESSRRVHTSTPSDKNLLDTYNTELLKSDSDNNNSDDCGNI LPSDIMDFVLKNTPSMQALGESPESSSSELLNLGEGLGLDSNREKDMGLFEVFSQQLPTTEPVDSSVSSSISAEEQFELPLELPSDLSVL TTRSPTVPSQNPSRLAVISDSGEKRVTITEKSVASSESDPALLSPGVDPTPEGHMTPDHFIQGHMDADHISSPPCGSVEQGHGNNQDLTR NSSTPGLQVPVSPTVPIQNQKYVPNSTDSPGPSQISNAAVQTTPPHLKPATEKLIVVNQNMQPLYVLQTLPNGVTQKIQLTSSVSSTPSV METNTSVLGPMGGGLTLTTGLNPSLPTSQSLFPSASKGLLPMSHHQHLHSFPAATQSSFPPNISNPPSGLLIGVQPPPDPQLLVSESSQR TDLSTTVATPSSGLKKRPISRLQTRKNKKLAPSSTPSNIAPSDVVSNMTLINFTPSQLPNHPSLLDLGSLNTSSHRTVPNIIKRSKSSIM YFEPAPLLPQSVGGTAATAAGTSTISQDTSHLTSGSVSGLASSSSVLNVVSMQTTTTPTSSASVPGHVTLTNPRLLGTPDIGSISNLLIK ASQQSLGIQDQPVALPPSSGMFPQLGTSQTPSTAAITAASSICVLPSTQTTGITAASPSGEADEHYQLQHVNQLLASKTGIHSSQRDLDS ASGPQVSNFTQTVDAPNSMGLEQNKALSSAVQASPTSPGGSPSSPSSGQRSASPSVPGPTKPKPKTKRFQLPLDKGNGKKHKVSHLRTSS SEAHIPDQETTSLTSGTGTPGAEAEQQDTASVEQSSQKECGQPAGQVAVLPEVQVTQNPANEQESAEPKTVEEEESNFSSPLMLWLQQEQ KRKESITEKKPKKGLVFEISSDDGFQICAESIEDAWKSLTDKVQEARSNARLKQLSFAGVNGLRMLGILHDAVVFLIEQLSGAKHCRNYK FRFHKPEEANEPPLNPHGSARAEVHLRKSAFDMFNFLASKHRQPPEYNPNDEEEEEVQLKSARRATSMDLPMPMRFRHLKKTSKEAVGVY RSPIHGRGLFCKRNIDAGEMVIEYAGNVIRSIQTDKREKYYDSKGIGCYMFRIDDSEVVDATMHGNAARFINHSCEPNCYSRVINIDGQK -------------------------------------------------------------- >2660_2660_17_AFF1-KMT2A_AFF1_chr4_87968746_ENST00000395146_KMT2A_chr11_118354897_ENST00000389506_length(amino acids)=2963AA_BP=356 METMAFTERVNSSGNSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKTAKGDELSSRIQNMLGNYEEVKEFLSTKSHTHRL DASENRLGKPKYPLIPDKGSSIPSSSFHTSVHHQSIHTPASGPLSVGNISHNPKMAQPRTEPMPSLHAKSCGPPDSQHLTQDRLGQEGFG SSHHKKGDRRADGDHCASVTDSAPERELSPLISLPSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNNSKGYCPAKSPKDLAVKVHDKETPQ DSLVAPAQPPSQTFPPPSLPSKSVAMQQKPTAYVRPMDGQDQAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEEKPP PVNKQENAGTLNILSTLSNGNSSKQKIPADGVHRIRVDFKEDCEAENVWEMGGLGILTSVPITPRVVCFLCASSGHVEFVYCQVCCEPFH KFCLEENERPLEDQLENWCCRRCKFCHVCGRQHQATKQLLECNKCRNSYHPECLGPNYPTKPTKKKKVWICTKCVRCKSCGSTTPGKGWD AQWSHDFSLCHDCAKLFAKGNFCPLCDKCYDDDDYESKMMQCGKCDRWVHSKCENLSDEMYEILSNLPESVAYTCVNCTERHPAEWRLAL EKELQISLKQVLTALLNSRTTSHLLRYRQAAKPPDLNPETEESIPSRSSPEGPDPPVLTEVSKQDDQQPLDLEGVKRKMDQGNYTSVLEF SDDIVKIIQAAINSDGGQPEIKKANSMVKSFFIRQMERVFPWFSVKKSRFWEPNKVSSNSGMLPNAVLPPSLDHNYAQWQEREENSHTEQ PPLMKKIIPAPKPKGPGEPDSPTPLHPPTPPILSTDRSREDSPELNPPPGIEDNRQCALCLTYGDDSANDAGRLLYIGQNEWTHVNCALW SAEVFEDDDGSLKNVHMAVIRGKQLRCEFCQKPGATVGCCLTSCTSNYHFMCSRAKNCVFLDDKKVYCQRHRDLIKGEVVPENGFEVFRR VFVDFEGISLRRKFLNGLEPENIHMMIGSMTIDCLGILNDLSDCEDKLFPIGYQCSRVYWSTTDARKRCVYTCKIVECRPPVVEPDINST VEHDENRTIAHSPTSFTESSSKESQNTAEIISPPSPDRPPHSQTSGSCYYHVISKVPRIRTPSYSPTQRSPGCRPLPSAGSPTPTTHEIV TVGDPLLSSGLRSIGSRRHSTSSLSPQRSKLRIMSPMRTGNTYSRNNVSSVSTTGTATDLESSAKVVDHVLGPLNSSTSLGQNTSTSSNL QRTVVTVGNKNSHLDGSSSSEMKQSSASDLVSKSSSLKGEKTKVLSSKSSEGSAHNVAYPGIPKLAPQVHNTTSRELNVSKIGSFAEPSS VSFSSKEALSFPHLHLRGQRNDRDQHTDSTQSANSSPDEDTEVKTLKLSGMSNRSSIINEHMGSSSRDRRQKGKKSCKETFKEKHSSKSF LEPGQVTTGEEGNLKPEFMDEVLTPEYMGQRPCNNVSSDKIGDKGLSMPGVPKAPPMQVEGSAKELQAPRKRTVKVTLTPLKMENESQSK NALKESSPASPLQIESTSPTEPISASENPGDGPVAQPSPNNTSCQDSQSNNYQNLPVQDRNLMLPDGPKPQEDGSFKRRYPRRSARARSN MFFGLTPLYGVRSYGEEDIPFYSSSTGKKRGKRSAEGQVDGADDLSTSDEDDLYYYNFTRTVISSGGEERLASHNLFREEEQCDLPKISQ LDGVDDGTESDTSVTATTRKSSQIPKRNGKENGTENLKIDRPEDAGEKEHVTKSSVGHKNEPKMDNCHSVSRVKTQGQDSLEAQLSSLES SRRVHTSTPSDKNLLDTYNTELLKSDSDNNNSDDCGNILPSDIMDFVLKNTPSMQALGESPESSSSELLNLGEGLGLDSNREKDMGLFEV FSQQLPTTEPVDSSVSSSISAEEQFELPLELPSDLSVLTTRSPTVPSQNPSRLAVISDSGEKRVTITEKSVASSESDPALLSPGVDPTPE GHMTPDHFIQGHMDADHISSPPCGSVEQGHGNNQDLTRNSSTPGLQVPVSPTVPIQNQKYVPNSTDSPGPSQISNAAVQTTPPHLKPATE KLIVVNQNMQPLYVLQTLPNGVTQKIQLTSSVSSTPSVMETNTSVLGPMGGGLTLTTGLNPSLPTSQSLFPSASKGLLPMSHHQHLHSFP AATQSSFPPNISNPPSGLLIGVQPPPDPQLLVSESSQRTDLSTTVATPSSGLKKRPISRLQTRKNKKLAPSSTPSNIAPSDVVSNMTLIN FTPSQLPNHPSLLDLGSLNTSSHRTVPNIIKRSKSSIMYFEPAPLLPQSVGGTAATAAGTSTISQDTSHLTSGSVSGLASSSSVLNVVSM QTTTTPTSSASVPGHVTLTNPRLLGTPDIGSISNLLIKASQQSLGIQDQPVALPPSSGMFPQLGTSQTPSTAAITAASSICVLPSTQTTG ITAASPSGEADEHYQLQHVNQLLASKTGIHSSQRDLDSASGPQVSNFTQTVDAPNSMGLEQNKALSSAVQASPTSPGGSPSSPSSGQRSA SPSVPGPTKPKPKTKRFQLPLDKGNGKKHKVSHLRTSSSEAHIPDQETTSLTSGTGTPGAEAEQQDTASVEQSSQKECGQPAGQVAVLPE VQVTQNPANEQESAEPKTVEEEESNFSSPLMLWLQQEQKRKESITEKKPKKGLVFEISSDDGFQICAESIEDAWKSLTDKVQEARSNARL KQLSFAGVNGLRMLGILHDAVVFLIEQLSGAKHCRNYKFRFHKPEEANEPPLNPHGSARAEVHLRKSAFDMFNFLASKHRQPPEYNPNDE EEEEVQLKSARRATSMDLPMPMRFRHLKKTSKEAVGVYRSPIHGRGLFCKRNIDAGEMVIEYAGNVIRSIQTDKREKYYDSKGIGCYMFR -------------------------------------------------------------- >2660_2660_18_AFF1-KMT2A_AFF1_chr4_87968746_ENST00000395146_KMT2A_chr11_118354897_ENST00000534358_length(amino acids)=2966AA_BP=356 METMAFTERVNSSGNSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKTAKGDELSSRIQNMLGNYEEVKEFLSTKSHTHRL DASENRLGKPKYPLIPDKGSSIPSSSFHTSVHHQSIHTPASGPLSVGNISHNPKMAQPRTEPMPSLHAKSCGPPDSQHLTQDRLGQEGFG SSHHKKGDRRADGDHCASVTDSAPERELSPLISLPSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNNSKGYCPAKSPKDLAVKVHDKETPQ DSLVAPAQPPSQTFPPPSLPSKSVAMQQKPTAYVRPMDGQDQAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEEKPP PVNKQENAGTLNILSTLSNGNSSKQKIPADGVHRIRVDFKEDCEAENVWEMGGLGILTSVPITPRVVCFLCASSGHVEFVYCQVCCEPFH KFCLEENERPLEDQLENWCCRRCKFCHVCGRQHQATKQLLECNKCRNSYHPECLGPNYPTKPTKKKKVWICTKCVRCKSCGSTTPGKGWD AQWSHDFSLCHDCAKLFAKGNFCPLCDKCYDDDDYESKMMQCGKCDRWVHSKCENLSGTEDEMYEILSNLPESVAYTCVNCTERHPAEWR LALEKELQISLKQVLTALLNSRTTSHLLRYRQAAKPPDLNPETEESIPSRSSPEGPDPPVLTEVSKQDDQQPLDLEGVKRKMDQGNYTSV LEFSDDIVKIIQAAINSDGGQPEIKKANSMVKSFFIRQMERVFPWFSVKKSRFWEPNKVSSNSGMLPNAVLPPSLDHNYAQWQEREENSH TEQPPLMKKIIPAPKPKGPGEPDSPTPLHPPTPPILSTDRSREDSPELNPPPGIEDNRQCALCLTYGDDSANDAGRLLYIGQNEWTHVNC ALWSAEVFEDDDGSLKNVHMAVIRGKQLRCEFCQKPGATVGCCLTSCTSNYHFMCSRAKNCVFLDDKKVYCQRHRDLIKGEVVPENGFEV FRRVFVDFEGISLRRKFLNGLEPENIHMMIGSMTIDCLGILNDLSDCEDKLFPIGYQCSRVYWSTTDARKRCVYTCKIVECRPPVVEPDI NSTVEHDENRTIAHSPTSFTESSSKESQNTAEIISPPSPDRPPHSQTSGSCYYHVISKVPRIRTPSYSPTQRSPGCRPLPSAGSPTPTTH EIVTVGDPLLSSGLRSIGSRRHSTSSLSPQRSKLRIMSPMRTGNTYSRNNVSSVSTTGTATDLESSAKVVDHVLGPLNSSTSLGQNTSTS SNLQRTVVTVGNKNSHLDGSSSSEMKQSSASDLVSKSSSLKGEKTKVLSSKSSEGSAHNVAYPGIPKLAPQVHNTTSRELNVSKIGSFAE PSSVSFSSKEALSFPHLHLRGQRNDRDQHTDSTQSANSSPDEDTEVKTLKLSGMSNRSSIINEHMGSSSRDRRQKGKKSCKETFKEKHSS KSFLEPGQVTTGEEGNLKPEFMDEVLTPEYMGQRPCNNVSSDKIGDKGLSMPGVPKAPPMQVEGSAKELQAPRKRTVKVTLTPLKMENES QSKNALKESSPASPLQIESTSPTEPISASENPGDGPVAQPSPNNTSCQDSQSNNYQNLPVQDRNLMLPDGPKPQEDGSFKRRYPRRSARA RSNMFFGLTPLYGVRSYGEEDIPFYSSSTGKKRGKRSAEGQVDGADDLSTSDEDDLYYYNFTRTVISSGGEERLASHNLFREEEQCDLPK ISQLDGVDDGTESDTSVTATTRKSSQIPKRNGKENGTENLKIDRPEDAGEKEHVTKSSVGHKNEPKMDNCHSVSRVKTQGQDSLEAQLSS LESSRRVHTSTPSDKNLLDTYNTELLKSDSDNNNSDDCGNILPSDIMDFVLKNTPSMQALGESPESSSSELLNLGEGLGLDSNREKDMGL FEVFSQQLPTTEPVDSSVSSSISAEEQFELPLELPSDLSVLTTRSPTVPSQNPSRLAVISDSGEKRVTITEKSVASSESDPALLSPGVDP TPEGHMTPDHFIQGHMDADHISSPPCGSVEQGHGNNQDLTRNSSTPGLQVPVSPTVPIQNQKYVPNSTDSPGPSQISNAAVQTTPPHLKP ATEKLIVVNQNMQPLYVLQTLPNGVTQKIQLTSSVSSTPSVMETNTSVLGPMGGGLTLTTGLNPSLPTSQSLFPSASKGLLPMSHHQHLH SFPAATQSSFPPNISNPPSGLLIGVQPPPDPQLLVSESSQRTDLSTTVATPSSGLKKRPISRLQTRKNKKLAPSSTPSNIAPSDVVSNMT LINFTPSQLPNHPSLLDLGSLNTSSHRTVPNIIKRSKSSIMYFEPAPLLPQSVGGTAATAAGTSTISQDTSHLTSGSVSGLASSSSVLNV VSMQTTTTPTSSASVPGHVTLTNPRLLGTPDIGSISNLLIKASQQSLGIQDQPVALPPSSGMFPQLGTSQTPSTAAITAASSICVLPSTQ TTGITAASPSGEADEHYQLQHVNQLLASKTGIHSSQRDLDSASGPQVSNFTQTVDAPNSMGLEQNKALSSAVQASPTSPGGSPSSPSSGQ RSASPSVPGPTKPKPKTKRFQLPLDKGNGKKHKVSHLRTSSSEAHIPDQETTSLTSGTGTPGAEAEQQDTASVEQSSQKECGQPAGQVAV LPEVQVTQNPANEQESAEPKTVEEEESNFSSPLMLWLQQEQKRKESITEKKPKKGLVFEISSDDGFQICAESIEDAWKSLTDKVQEARSN ARLKQLSFAGVNGLRMLGILHDAVVFLIEQLSGAKHCRNYKFRFHKPEEANEPPLNPHGSARAEVHLRKSAFDMFNFLASKHRQPPEYNP NDEEEEEVQLKSARRATSMDLPMPMRFRHLKKTSKEAVGVYRSPIHGRGLFCKRNIDAGEMVIEYAGNVIRSIQTDKREKYYDSKGIGCY -------------------------------------------------------------- >2660_2660_19_AFF1-KMT2A_AFF1_chr4_87968747_ENST00000307808_KMT2A_chr11_118354896_ENST00000354520_length(amino acids)=2915AA_BP=346 MAAQSSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKTAKGDELSSRIQNMLGNYEEVKEFLSTKSHTHRLDASENRLGKP KYPLIPDKGSSIPSSSFHTSVHHQSIHTPASGPLSVGNISHNPKMAQPRTEPMPSLHAKSCGPPDSQHLTQDRLGQEGFGSSHHKKGDRR ADGDHCASVTDSAPERELSPLISLPSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNNSKGYCPAKSPKDLAVKVHDKETPQDSLVAPAQPP SQTFPPPSLPSKSVAMQQKPTAYVRPMDGQDQAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEEKPPPVNKQENAGT LNILSTLSNGNSSKQKIPADGVHRIRVDFKFVYCQVCCEPFHKFCLEENERPLEDQLENWCCRRCKFCHVCGRQHQATKQLLECNKCRNS YHPECLGPNYPTKPTKKKKVWICTKCVRCKSCGSTTPGKGWDAQWSHDFSLCHDCAKLFAKGNFCPLCDKCYDDDDYESKMMQCGKCDRW VHSKCENLSDEMYEILSNLPESVAYTCVNCTERHPAEWRLALEKELQISLKQVLTALLNSRTTSHLLRYRQAAKPPDLNPETEESIPSRS SPEGPDPPVLTEVSKQDDQQPLDLEGVKRKMDQGNYTSVLEFSDDIVKIIQAAINSDGGQPEIKKANSMVKSFFIRQMERVFPWFSVKKS RFWEPNKVSSNSGMLPNAVLPPSLDHNYAQWQEREENSHTEQPPLMKKIIPAPKPKGPGEPDSPTPLHPPTPPILSTDRSREDSPELNPP PGIEDNRQCALCLTYGDDSANDAGRLLYIGQNEWTHVNCALWSAEVFEDDDGSLKNVHMAVIRGKQLRCEFCQKPGATVGCCLTSCTSNY HFMCSRAKNCVFLDDKKVYCQRHRDLIKGEVVPENGFEVFRRVFVDFEGISLRRKFLNGLEPENIHMMIGSMTIDCLGILNDLSDCEDKL FPIGYQCSRVYWSTTDARKRCVYTCKIVECRPPVVEPDINSTVEHDENRTIAHSPTSFTESSSKESQNTAEIISPPSPDRPPHSQTSGSC YYHVISKVPRIRTPSYSPTQRSPGCRPLPSAGSPTPTTHEIVTVGDPLLSSGLRSIGSRRHSTSSLSPQRSKLRIMSPMRTGNTYSRNNV SSVSTTGTATDLESSAKVVDHVLGPLNSSTSLGQNTSTSSNLQRTVVTVGNKNSHLDGSSSSEMKQSSASDLVSKSSSLKGEKTKVLSSK SSEGSAHNVAYPGIPKLAPQVHNTTSRELNVSKIGSFAEPSSVSFSSKEALSFPHLHLRGQRNDRDQHTDSTQSANSSPDEDTEVKTLKL SGMSNRSSIINEHMGSSSRDRRQKGKKSCKETFKEKHSSKSFLEPGQVTTGEEGNLKPEFMDEVLTPEYMGQRPCNNVSSDKIGDKGLSM PGVPKAPPMQVEGSAKELQAPRKRTVKVTLTPLKMENESQSKNALKESSPASPLQIESTSPTEPISASENPGDGPVAQPSPNNTSCQDSQ SNNYQNLPVQDRNLMLPDGPKPQEDGSFKRRYPRRSARARSNMFFGLTPLYGVRSYGEEDIPFYSSSTGKKRGKRSAEGQVDGADDLSTS DEDDLYYYNFTRTVISSGGEERLASHNLFREEEQCDLPKISQLDGVDDGTESDTSVTATTRKSSQIPKRNGKENGTENLKIDRPEDAGEK EHVTKSSVGHKNEPKMDNCHSVSRVKTQGQDSLEAQLSSLESSRRVHTSTPSDKNLLDTYNTELLKSDSDNNNSDDCGNILPSDIMDFVL KNTPSMQALGESPESSSSELLNLGEGLGLDSNREKDMGLFEVFSQQLPTTEPVDSSVSSSISAEEQFELPLELPSDLSVLTTRSPTVPSQ NPSRLAVISDSGEKRVTITEKSVASSESDPALLSPGVDPTPEGHMTPDHFIQGHMDADHISSPPCGSVEQGHGNNQDLTRNSSTPGLQVP VSPTVPIQNQKYVPNSTDSPGPSQISNAAVQTTPPHLKPATEKLIVVNQNMQPLYVLQTLPNGVTQKIQLTSSVSSTPSVMETNTSVLGP MGGGLTLTTGLNPSLPTSQSLFPSASKGLLPMSHHQHLHSFPAATQSSFPPNISNPPSGLLIGVQPPPDPQLLVSESSQRTDLSTTVATP SSGLKKRPISRLQTRKNKKLAPSSTPSNIAPSDVVSNMTLINFTPSQLPNHPSLLDLGSLNTSSHRTVPNIIKRSKSSIMYFEPAPLLPQ SVGGTAATAAGTSTISQDTSHLTSGSVSGLASSSSVLNVVSMQTTTTPTSSASVPGHVTLTNPRLLGTPDIGSISNLLIKASQQSLGIQD QPVALPPSSGMFPQLGTSQTPSTAAITAASSICVLPSTQTTGITAASPSGEADEHYQLQHVNQLLASKTGIHSSQRDLDSASGPQVSNFT QTVDAPNSMGLEQNKALSSAVQASPTSPGGSPSSPSSGQRSASPSVPGPTKPKPKTKRFQLPLDKGNGKKHKVSHLRTSSSEAHIPDQET TSLTSGTGTPGAEAEQQDTASVEQSSQKECGQPAGQVAVLPEVQVTQNPANEQESAEPKTVEEEESNFSSPLMLWLQQEQKRKESITEKK PKKGLVFEISSDDGFQICAESIEDAWKSLTDKVQEARSNARLKQLSFAGVNGLRMLGILHDAVVFLIEQLSGAKHCRNYKFRFHKPEEAN EPPLNPHGSARAEVHLRKSAFDMFNFLASKHRQPPEYNPNDEEEEEVQLKSARRATSMDLPMPMRFRHLKKTSKEAVGVYRSPIHGRGLF CKRNIDAGEMVIEYAGNVIRSIQTDKREKYYDSKGIGCYMFRIDDSEVVDATMHGNAARFINHSCEPNCYSRVINIDGQKHIVIFAMRKI -------------------------------------------------------------- >2660_2660_20_AFF1-KMT2A_AFF1_chr4_87968747_ENST00000307808_KMT2A_chr11_118354896_ENST00000389506_length(amino acids)=2953AA_BP=346 MAAQSSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKTAKGDELSSRIQNMLGNYEEVKEFLSTKSHTHRLDASENRLGKP KYPLIPDKGSSIPSSSFHTSVHHQSIHTPASGPLSVGNISHNPKMAQPRTEPMPSLHAKSCGPPDSQHLTQDRLGQEGFGSSHHKKGDRR ADGDHCASVTDSAPERELSPLISLPSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNNSKGYCPAKSPKDLAVKVHDKETPQDSLVAPAQPP SQTFPPPSLPSKSVAMQQKPTAYVRPMDGQDQAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEEKPPPVNKQENAGT LNILSTLSNGNSSKQKIPADGVHRIRVDFKEDCEAENVWEMGGLGILTSVPITPRVVCFLCASSGHVEFVYCQVCCEPFHKFCLEENERP LEDQLENWCCRRCKFCHVCGRQHQATKQLLECNKCRNSYHPECLGPNYPTKPTKKKKVWICTKCVRCKSCGSTTPGKGWDAQWSHDFSLC HDCAKLFAKGNFCPLCDKCYDDDDYESKMMQCGKCDRWVHSKCENLSDEMYEILSNLPESVAYTCVNCTERHPAEWRLALEKELQISLKQ VLTALLNSRTTSHLLRYRQAAKPPDLNPETEESIPSRSSPEGPDPPVLTEVSKQDDQQPLDLEGVKRKMDQGNYTSVLEFSDDIVKIIQA AINSDGGQPEIKKANSMVKSFFIRQMERVFPWFSVKKSRFWEPNKVSSNSGMLPNAVLPPSLDHNYAQWQEREENSHTEQPPLMKKIIPA PKPKGPGEPDSPTPLHPPTPPILSTDRSREDSPELNPPPGIEDNRQCALCLTYGDDSANDAGRLLYIGQNEWTHVNCALWSAEVFEDDDG SLKNVHMAVIRGKQLRCEFCQKPGATVGCCLTSCTSNYHFMCSRAKNCVFLDDKKVYCQRHRDLIKGEVVPENGFEVFRRVFVDFEGISL RRKFLNGLEPENIHMMIGSMTIDCLGILNDLSDCEDKLFPIGYQCSRVYWSTTDARKRCVYTCKIVECRPPVVEPDINSTVEHDENRTIA HSPTSFTESSSKESQNTAEIISPPSPDRPPHSQTSGSCYYHVISKVPRIRTPSYSPTQRSPGCRPLPSAGSPTPTTHEIVTVGDPLLSSG LRSIGSRRHSTSSLSPQRSKLRIMSPMRTGNTYSRNNVSSVSTTGTATDLESSAKVVDHVLGPLNSSTSLGQNTSTSSNLQRTVVTVGNK NSHLDGSSSSEMKQSSASDLVSKSSSLKGEKTKVLSSKSSEGSAHNVAYPGIPKLAPQVHNTTSRELNVSKIGSFAEPSSVSFSSKEALS FPHLHLRGQRNDRDQHTDSTQSANSSPDEDTEVKTLKLSGMSNRSSIINEHMGSSSRDRRQKGKKSCKETFKEKHSSKSFLEPGQVTTGE EGNLKPEFMDEVLTPEYMGQRPCNNVSSDKIGDKGLSMPGVPKAPPMQVEGSAKELQAPRKRTVKVTLTPLKMENESQSKNALKESSPAS PLQIESTSPTEPISASENPGDGPVAQPSPNNTSCQDSQSNNYQNLPVQDRNLMLPDGPKPQEDGSFKRRYPRRSARARSNMFFGLTPLYG VRSYGEEDIPFYSSSTGKKRGKRSAEGQVDGADDLSTSDEDDLYYYNFTRTVISSGGEERLASHNLFREEEQCDLPKISQLDGVDDGTES DTSVTATTRKSSQIPKRNGKENGTENLKIDRPEDAGEKEHVTKSSVGHKNEPKMDNCHSVSRVKTQGQDSLEAQLSSLESSRRVHTSTPS DKNLLDTYNTELLKSDSDNNNSDDCGNILPSDIMDFVLKNTPSMQALGESPESSSSELLNLGEGLGLDSNREKDMGLFEVFSQQLPTTEP VDSSVSSSISAEEQFELPLELPSDLSVLTTRSPTVPSQNPSRLAVISDSGEKRVTITEKSVASSESDPALLSPGVDPTPEGHMTPDHFIQ GHMDADHISSPPCGSVEQGHGNNQDLTRNSSTPGLQVPVSPTVPIQNQKYVPNSTDSPGPSQISNAAVQTTPPHLKPATEKLIVVNQNMQ PLYVLQTLPNGVTQKIQLTSSVSSTPSVMETNTSVLGPMGGGLTLTTGLNPSLPTSQSLFPSASKGLLPMSHHQHLHSFPAATQSSFPPN ISNPPSGLLIGVQPPPDPQLLVSESSQRTDLSTTVATPSSGLKKRPISRLQTRKNKKLAPSSTPSNIAPSDVVSNMTLINFTPSQLPNHP SLLDLGSLNTSSHRTVPNIIKRSKSSIMYFEPAPLLPQSVGGTAATAAGTSTISQDTSHLTSGSVSGLASSSSVLNVVSMQTTTTPTSSA SVPGHVTLTNPRLLGTPDIGSISNLLIKASQQSLGIQDQPVALPPSSGMFPQLGTSQTPSTAAITAASSICVLPSTQTTGITAASPSGEA DEHYQLQHVNQLLASKTGIHSSQRDLDSASGPQVSNFTQTVDAPNSMGLEQNKALSSAVQASPTSPGGSPSSPSSGQRSASPSVPGPTKP KPKTKRFQLPLDKGNGKKHKVSHLRTSSSEAHIPDQETTSLTSGTGTPGAEAEQQDTASVEQSSQKECGQPAGQVAVLPEVQVTQNPANE QESAEPKTVEEEESNFSSPLMLWLQQEQKRKESITEKKPKKGLVFEISSDDGFQICAESIEDAWKSLTDKVQEARSNARLKQLSFAGVNG LRMLGILHDAVVFLIEQLSGAKHCRNYKFRFHKPEEANEPPLNPHGSARAEVHLRKSAFDMFNFLASKHRQPPEYNPNDEEEEEVQLKSA RRATSMDLPMPMRFRHLKKTSKEAVGVYRSPIHGRGLFCKRNIDAGEMVIEYAGNVIRSIQTDKREKYYDSKGIGCYMFRIDDSEVVDAT -------------------------------------------------------------- >2660_2660_21_AFF1-KMT2A_AFF1_chr4_87968747_ENST00000307808_KMT2A_chr11_118354896_ENST00000534358_length(amino acids)=2956AA_BP=346 MAAQSSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKTAKGDELSSRIQNMLGNYEEVKEFLSTKSHTHRLDASENRLGKP KYPLIPDKGSSIPSSSFHTSVHHQSIHTPASGPLSVGNISHNPKMAQPRTEPMPSLHAKSCGPPDSQHLTQDRLGQEGFGSSHHKKGDRR ADGDHCASVTDSAPERELSPLISLPSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNNSKGYCPAKSPKDLAVKVHDKETPQDSLVAPAQPP SQTFPPPSLPSKSVAMQQKPTAYVRPMDGQDQAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEEKPPPVNKQENAGT LNILSTLSNGNSSKQKIPADGVHRIRVDFKEDCEAENVWEMGGLGILTSVPITPRVVCFLCASSGHVEFVYCQVCCEPFHKFCLEENERP LEDQLENWCCRRCKFCHVCGRQHQATKQLLECNKCRNSYHPECLGPNYPTKPTKKKKVWICTKCVRCKSCGSTTPGKGWDAQWSHDFSLC HDCAKLFAKGNFCPLCDKCYDDDDYESKMMQCGKCDRWVHSKCENLSGTEDEMYEILSNLPESVAYTCVNCTERHPAEWRLALEKELQIS LKQVLTALLNSRTTSHLLRYRQAAKPPDLNPETEESIPSRSSPEGPDPPVLTEVSKQDDQQPLDLEGVKRKMDQGNYTSVLEFSDDIVKI IQAAINSDGGQPEIKKANSMVKSFFIRQMERVFPWFSVKKSRFWEPNKVSSNSGMLPNAVLPPSLDHNYAQWQEREENSHTEQPPLMKKI IPAPKPKGPGEPDSPTPLHPPTPPILSTDRSREDSPELNPPPGIEDNRQCALCLTYGDDSANDAGRLLYIGQNEWTHVNCALWSAEVFED DDGSLKNVHMAVIRGKQLRCEFCQKPGATVGCCLTSCTSNYHFMCSRAKNCVFLDDKKVYCQRHRDLIKGEVVPENGFEVFRRVFVDFEG ISLRRKFLNGLEPENIHMMIGSMTIDCLGILNDLSDCEDKLFPIGYQCSRVYWSTTDARKRCVYTCKIVECRPPVVEPDINSTVEHDENR TIAHSPTSFTESSSKESQNTAEIISPPSPDRPPHSQTSGSCYYHVISKVPRIRTPSYSPTQRSPGCRPLPSAGSPTPTTHEIVTVGDPLL SSGLRSIGSRRHSTSSLSPQRSKLRIMSPMRTGNTYSRNNVSSVSTTGTATDLESSAKVVDHVLGPLNSSTSLGQNTSTSSNLQRTVVTV GNKNSHLDGSSSSEMKQSSASDLVSKSSSLKGEKTKVLSSKSSEGSAHNVAYPGIPKLAPQVHNTTSRELNVSKIGSFAEPSSVSFSSKE ALSFPHLHLRGQRNDRDQHTDSTQSANSSPDEDTEVKTLKLSGMSNRSSIINEHMGSSSRDRRQKGKKSCKETFKEKHSSKSFLEPGQVT TGEEGNLKPEFMDEVLTPEYMGQRPCNNVSSDKIGDKGLSMPGVPKAPPMQVEGSAKELQAPRKRTVKVTLTPLKMENESQSKNALKESS PASPLQIESTSPTEPISASENPGDGPVAQPSPNNTSCQDSQSNNYQNLPVQDRNLMLPDGPKPQEDGSFKRRYPRRSARARSNMFFGLTP LYGVRSYGEEDIPFYSSSTGKKRGKRSAEGQVDGADDLSTSDEDDLYYYNFTRTVISSGGEERLASHNLFREEEQCDLPKISQLDGVDDG TESDTSVTATTRKSSQIPKRNGKENGTENLKIDRPEDAGEKEHVTKSSVGHKNEPKMDNCHSVSRVKTQGQDSLEAQLSSLESSRRVHTS TPSDKNLLDTYNTELLKSDSDNNNSDDCGNILPSDIMDFVLKNTPSMQALGESPESSSSELLNLGEGLGLDSNREKDMGLFEVFSQQLPT TEPVDSSVSSSISAEEQFELPLELPSDLSVLTTRSPTVPSQNPSRLAVISDSGEKRVTITEKSVASSESDPALLSPGVDPTPEGHMTPDH FIQGHMDADHISSPPCGSVEQGHGNNQDLTRNSSTPGLQVPVSPTVPIQNQKYVPNSTDSPGPSQISNAAVQTTPPHLKPATEKLIVVNQ NMQPLYVLQTLPNGVTQKIQLTSSVSSTPSVMETNTSVLGPMGGGLTLTTGLNPSLPTSQSLFPSASKGLLPMSHHQHLHSFPAATQSSF PPNISNPPSGLLIGVQPPPDPQLLVSESSQRTDLSTTVATPSSGLKKRPISRLQTRKNKKLAPSSTPSNIAPSDVVSNMTLINFTPSQLP NHPSLLDLGSLNTSSHRTVPNIIKRSKSSIMYFEPAPLLPQSVGGTAATAAGTSTISQDTSHLTSGSVSGLASSSSVLNVVSMQTTTTPT SSASVPGHVTLTNPRLLGTPDIGSISNLLIKASQQSLGIQDQPVALPPSSGMFPQLGTSQTPSTAAITAASSICVLPSTQTTGITAASPS GEADEHYQLQHVNQLLASKTGIHSSQRDLDSASGPQVSNFTQTVDAPNSMGLEQNKALSSAVQASPTSPGGSPSSPSSGQRSASPSVPGP TKPKPKTKRFQLPLDKGNGKKHKVSHLRTSSSEAHIPDQETTSLTSGTGTPGAEAEQQDTASVEQSSQKECGQPAGQVAVLPEVQVTQNP ANEQESAEPKTVEEEESNFSSPLMLWLQQEQKRKESITEKKPKKGLVFEISSDDGFQICAESIEDAWKSLTDKVQEARSNARLKQLSFAG VNGLRMLGILHDAVVFLIEQLSGAKHCRNYKFRFHKPEEANEPPLNPHGSARAEVHLRKSAFDMFNFLASKHRQPPEYNPNDEEEEEVQL KSARRATSMDLPMPMRFRHLKKTSKEAVGVYRSPIHGRGLFCKRNIDAGEMVIEYAGNVIRSIQTDKREKYYDSKGIGCYMFRIDDSEVV -------------------------------------------------------------- >2660_2660_22_AFF1-KMT2A_AFF1_chr4_87968747_ENST00000395146_KMT2A_chr11_118354896_ENST00000354520_length(amino acids)=2925AA_BP=356 METMAFTERVNSSGNSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKTAKGDELSSRIQNMLGNYEEVKEFLSTKSHTHRL DASENRLGKPKYPLIPDKGSSIPSSSFHTSVHHQSIHTPASGPLSVGNISHNPKMAQPRTEPMPSLHAKSCGPPDSQHLTQDRLGQEGFG SSHHKKGDRRADGDHCASVTDSAPERELSPLISLPSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNNSKGYCPAKSPKDLAVKVHDKETPQ DSLVAPAQPPSQTFPPPSLPSKSVAMQQKPTAYVRPMDGQDQAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEEKPP PVNKQENAGTLNILSTLSNGNSSKQKIPADGVHRIRVDFKFVYCQVCCEPFHKFCLEENERPLEDQLENWCCRRCKFCHVCGRQHQATKQ LLECNKCRNSYHPECLGPNYPTKPTKKKKVWICTKCVRCKSCGSTTPGKGWDAQWSHDFSLCHDCAKLFAKGNFCPLCDKCYDDDDYESK MMQCGKCDRWVHSKCENLSDEMYEILSNLPESVAYTCVNCTERHPAEWRLALEKELQISLKQVLTALLNSRTTSHLLRYRQAAKPPDLNP ETEESIPSRSSPEGPDPPVLTEVSKQDDQQPLDLEGVKRKMDQGNYTSVLEFSDDIVKIIQAAINSDGGQPEIKKANSMVKSFFIRQMER VFPWFSVKKSRFWEPNKVSSNSGMLPNAVLPPSLDHNYAQWQEREENSHTEQPPLMKKIIPAPKPKGPGEPDSPTPLHPPTPPILSTDRS REDSPELNPPPGIEDNRQCALCLTYGDDSANDAGRLLYIGQNEWTHVNCALWSAEVFEDDDGSLKNVHMAVIRGKQLRCEFCQKPGATVG CCLTSCTSNYHFMCSRAKNCVFLDDKKVYCQRHRDLIKGEVVPENGFEVFRRVFVDFEGISLRRKFLNGLEPENIHMMIGSMTIDCLGIL NDLSDCEDKLFPIGYQCSRVYWSTTDARKRCVYTCKIVECRPPVVEPDINSTVEHDENRTIAHSPTSFTESSSKESQNTAEIISPPSPDR PPHSQTSGSCYYHVISKVPRIRTPSYSPTQRSPGCRPLPSAGSPTPTTHEIVTVGDPLLSSGLRSIGSRRHSTSSLSPQRSKLRIMSPMR TGNTYSRNNVSSVSTTGTATDLESSAKVVDHVLGPLNSSTSLGQNTSTSSNLQRTVVTVGNKNSHLDGSSSSEMKQSSASDLVSKSSSLK GEKTKVLSSKSSEGSAHNVAYPGIPKLAPQVHNTTSRELNVSKIGSFAEPSSVSFSSKEALSFPHLHLRGQRNDRDQHTDSTQSANSSPD EDTEVKTLKLSGMSNRSSIINEHMGSSSRDRRQKGKKSCKETFKEKHSSKSFLEPGQVTTGEEGNLKPEFMDEVLTPEYMGQRPCNNVSS DKIGDKGLSMPGVPKAPPMQVEGSAKELQAPRKRTVKVTLTPLKMENESQSKNALKESSPASPLQIESTSPTEPISASENPGDGPVAQPS PNNTSCQDSQSNNYQNLPVQDRNLMLPDGPKPQEDGSFKRRYPRRSARARSNMFFGLTPLYGVRSYGEEDIPFYSSSTGKKRGKRSAEGQ VDGADDLSTSDEDDLYYYNFTRTVISSGGEERLASHNLFREEEQCDLPKISQLDGVDDGTESDTSVTATTRKSSQIPKRNGKENGTENLK IDRPEDAGEKEHVTKSSVGHKNEPKMDNCHSVSRVKTQGQDSLEAQLSSLESSRRVHTSTPSDKNLLDTYNTELLKSDSDNNNSDDCGNI LPSDIMDFVLKNTPSMQALGESPESSSSELLNLGEGLGLDSNREKDMGLFEVFSQQLPTTEPVDSSVSSSISAEEQFELPLELPSDLSVL TTRSPTVPSQNPSRLAVISDSGEKRVTITEKSVASSESDPALLSPGVDPTPEGHMTPDHFIQGHMDADHISSPPCGSVEQGHGNNQDLTR NSSTPGLQVPVSPTVPIQNQKYVPNSTDSPGPSQISNAAVQTTPPHLKPATEKLIVVNQNMQPLYVLQTLPNGVTQKIQLTSSVSSTPSV METNTSVLGPMGGGLTLTTGLNPSLPTSQSLFPSASKGLLPMSHHQHLHSFPAATQSSFPPNISNPPSGLLIGVQPPPDPQLLVSESSQR TDLSTTVATPSSGLKKRPISRLQTRKNKKLAPSSTPSNIAPSDVVSNMTLINFTPSQLPNHPSLLDLGSLNTSSHRTVPNIIKRSKSSIM YFEPAPLLPQSVGGTAATAAGTSTISQDTSHLTSGSVSGLASSSSVLNVVSMQTTTTPTSSASVPGHVTLTNPRLLGTPDIGSISNLLIK ASQQSLGIQDQPVALPPSSGMFPQLGTSQTPSTAAITAASSICVLPSTQTTGITAASPSGEADEHYQLQHVNQLLASKTGIHSSQRDLDS ASGPQVSNFTQTVDAPNSMGLEQNKALSSAVQASPTSPGGSPSSPSSGQRSASPSVPGPTKPKPKTKRFQLPLDKGNGKKHKVSHLRTSS SEAHIPDQETTSLTSGTGTPGAEAEQQDTASVEQSSQKECGQPAGQVAVLPEVQVTQNPANEQESAEPKTVEEEESNFSSPLMLWLQQEQ KRKESITEKKPKKGLVFEISSDDGFQICAESIEDAWKSLTDKVQEARSNARLKQLSFAGVNGLRMLGILHDAVVFLIEQLSGAKHCRNYK FRFHKPEEANEPPLNPHGSARAEVHLRKSAFDMFNFLASKHRQPPEYNPNDEEEEEVQLKSARRATSMDLPMPMRFRHLKKTSKEAVGVY RSPIHGRGLFCKRNIDAGEMVIEYAGNVIRSIQTDKREKYYDSKGIGCYMFRIDDSEVVDATMHGNAARFINHSCEPNCYSRVINIDGQK -------------------------------------------------------------- >2660_2660_23_AFF1-KMT2A_AFF1_chr4_87968747_ENST00000395146_KMT2A_chr11_118354896_ENST00000389506_length(amino acids)=2963AA_BP=356 METMAFTERVNSSGNSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKTAKGDELSSRIQNMLGNYEEVKEFLSTKSHTHRL DASENRLGKPKYPLIPDKGSSIPSSSFHTSVHHQSIHTPASGPLSVGNISHNPKMAQPRTEPMPSLHAKSCGPPDSQHLTQDRLGQEGFG SSHHKKGDRRADGDHCASVTDSAPERELSPLISLPSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNNSKGYCPAKSPKDLAVKVHDKETPQ DSLVAPAQPPSQTFPPPSLPSKSVAMQQKPTAYVRPMDGQDQAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEEKPP PVNKQENAGTLNILSTLSNGNSSKQKIPADGVHRIRVDFKEDCEAENVWEMGGLGILTSVPITPRVVCFLCASSGHVEFVYCQVCCEPFH KFCLEENERPLEDQLENWCCRRCKFCHVCGRQHQATKQLLECNKCRNSYHPECLGPNYPTKPTKKKKVWICTKCVRCKSCGSTTPGKGWD AQWSHDFSLCHDCAKLFAKGNFCPLCDKCYDDDDYESKMMQCGKCDRWVHSKCENLSDEMYEILSNLPESVAYTCVNCTERHPAEWRLAL EKELQISLKQVLTALLNSRTTSHLLRYRQAAKPPDLNPETEESIPSRSSPEGPDPPVLTEVSKQDDQQPLDLEGVKRKMDQGNYTSVLEF SDDIVKIIQAAINSDGGQPEIKKANSMVKSFFIRQMERVFPWFSVKKSRFWEPNKVSSNSGMLPNAVLPPSLDHNYAQWQEREENSHTEQ PPLMKKIIPAPKPKGPGEPDSPTPLHPPTPPILSTDRSREDSPELNPPPGIEDNRQCALCLTYGDDSANDAGRLLYIGQNEWTHVNCALW SAEVFEDDDGSLKNVHMAVIRGKQLRCEFCQKPGATVGCCLTSCTSNYHFMCSRAKNCVFLDDKKVYCQRHRDLIKGEVVPENGFEVFRR VFVDFEGISLRRKFLNGLEPENIHMMIGSMTIDCLGILNDLSDCEDKLFPIGYQCSRVYWSTTDARKRCVYTCKIVECRPPVVEPDINST VEHDENRTIAHSPTSFTESSSKESQNTAEIISPPSPDRPPHSQTSGSCYYHVISKVPRIRTPSYSPTQRSPGCRPLPSAGSPTPTTHEIV TVGDPLLSSGLRSIGSRRHSTSSLSPQRSKLRIMSPMRTGNTYSRNNVSSVSTTGTATDLESSAKVVDHVLGPLNSSTSLGQNTSTSSNL QRTVVTVGNKNSHLDGSSSSEMKQSSASDLVSKSSSLKGEKTKVLSSKSSEGSAHNVAYPGIPKLAPQVHNTTSRELNVSKIGSFAEPSS VSFSSKEALSFPHLHLRGQRNDRDQHTDSTQSANSSPDEDTEVKTLKLSGMSNRSSIINEHMGSSSRDRRQKGKKSCKETFKEKHSSKSF LEPGQVTTGEEGNLKPEFMDEVLTPEYMGQRPCNNVSSDKIGDKGLSMPGVPKAPPMQVEGSAKELQAPRKRTVKVTLTPLKMENESQSK NALKESSPASPLQIESTSPTEPISASENPGDGPVAQPSPNNTSCQDSQSNNYQNLPVQDRNLMLPDGPKPQEDGSFKRRYPRRSARARSN MFFGLTPLYGVRSYGEEDIPFYSSSTGKKRGKRSAEGQVDGADDLSTSDEDDLYYYNFTRTVISSGGEERLASHNLFREEEQCDLPKISQ LDGVDDGTESDTSVTATTRKSSQIPKRNGKENGTENLKIDRPEDAGEKEHVTKSSVGHKNEPKMDNCHSVSRVKTQGQDSLEAQLSSLES SRRVHTSTPSDKNLLDTYNTELLKSDSDNNNSDDCGNILPSDIMDFVLKNTPSMQALGESPESSSSELLNLGEGLGLDSNREKDMGLFEV FSQQLPTTEPVDSSVSSSISAEEQFELPLELPSDLSVLTTRSPTVPSQNPSRLAVISDSGEKRVTITEKSVASSESDPALLSPGVDPTPE GHMTPDHFIQGHMDADHISSPPCGSVEQGHGNNQDLTRNSSTPGLQVPVSPTVPIQNQKYVPNSTDSPGPSQISNAAVQTTPPHLKPATE KLIVVNQNMQPLYVLQTLPNGVTQKIQLTSSVSSTPSVMETNTSVLGPMGGGLTLTTGLNPSLPTSQSLFPSASKGLLPMSHHQHLHSFP AATQSSFPPNISNPPSGLLIGVQPPPDPQLLVSESSQRTDLSTTVATPSSGLKKRPISRLQTRKNKKLAPSSTPSNIAPSDVVSNMTLIN FTPSQLPNHPSLLDLGSLNTSSHRTVPNIIKRSKSSIMYFEPAPLLPQSVGGTAATAAGTSTISQDTSHLTSGSVSGLASSSSVLNVVSM QTTTTPTSSASVPGHVTLTNPRLLGTPDIGSISNLLIKASQQSLGIQDQPVALPPSSGMFPQLGTSQTPSTAAITAASSICVLPSTQTTG ITAASPSGEADEHYQLQHVNQLLASKTGIHSSQRDLDSASGPQVSNFTQTVDAPNSMGLEQNKALSSAVQASPTSPGGSPSSPSSGQRSA SPSVPGPTKPKPKTKRFQLPLDKGNGKKHKVSHLRTSSSEAHIPDQETTSLTSGTGTPGAEAEQQDTASVEQSSQKECGQPAGQVAVLPE VQVTQNPANEQESAEPKTVEEEESNFSSPLMLWLQQEQKRKESITEKKPKKGLVFEISSDDGFQICAESIEDAWKSLTDKVQEARSNARL KQLSFAGVNGLRMLGILHDAVVFLIEQLSGAKHCRNYKFRFHKPEEANEPPLNPHGSARAEVHLRKSAFDMFNFLASKHRQPPEYNPNDE EEEEVQLKSARRATSMDLPMPMRFRHLKKTSKEAVGVYRSPIHGRGLFCKRNIDAGEMVIEYAGNVIRSIQTDKREKYYDSKGIGCYMFR -------------------------------------------------------------- >2660_2660_24_AFF1-KMT2A_AFF1_chr4_87968747_ENST00000395146_KMT2A_chr11_118354896_ENST00000534358_length(amino acids)=2966AA_BP=356 METMAFTERVNSSGNSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKTAKGDELSSRIQNMLGNYEEVKEFLSTKSHTHRL DASENRLGKPKYPLIPDKGSSIPSSSFHTSVHHQSIHTPASGPLSVGNISHNPKMAQPRTEPMPSLHAKSCGPPDSQHLTQDRLGQEGFG SSHHKKGDRRADGDHCASVTDSAPERELSPLISLPSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNNSKGYCPAKSPKDLAVKVHDKETPQ DSLVAPAQPPSQTFPPPSLPSKSVAMQQKPTAYVRPMDGQDQAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEEKPP PVNKQENAGTLNILSTLSNGNSSKQKIPADGVHRIRVDFKEDCEAENVWEMGGLGILTSVPITPRVVCFLCASSGHVEFVYCQVCCEPFH KFCLEENERPLEDQLENWCCRRCKFCHVCGRQHQATKQLLECNKCRNSYHPECLGPNYPTKPTKKKKVWICTKCVRCKSCGSTTPGKGWD AQWSHDFSLCHDCAKLFAKGNFCPLCDKCYDDDDYESKMMQCGKCDRWVHSKCENLSGTEDEMYEILSNLPESVAYTCVNCTERHPAEWR LALEKELQISLKQVLTALLNSRTTSHLLRYRQAAKPPDLNPETEESIPSRSSPEGPDPPVLTEVSKQDDQQPLDLEGVKRKMDQGNYTSV LEFSDDIVKIIQAAINSDGGQPEIKKANSMVKSFFIRQMERVFPWFSVKKSRFWEPNKVSSNSGMLPNAVLPPSLDHNYAQWQEREENSH TEQPPLMKKIIPAPKPKGPGEPDSPTPLHPPTPPILSTDRSREDSPELNPPPGIEDNRQCALCLTYGDDSANDAGRLLYIGQNEWTHVNC ALWSAEVFEDDDGSLKNVHMAVIRGKQLRCEFCQKPGATVGCCLTSCTSNYHFMCSRAKNCVFLDDKKVYCQRHRDLIKGEVVPENGFEV FRRVFVDFEGISLRRKFLNGLEPENIHMMIGSMTIDCLGILNDLSDCEDKLFPIGYQCSRVYWSTTDARKRCVYTCKIVECRPPVVEPDI NSTVEHDENRTIAHSPTSFTESSSKESQNTAEIISPPSPDRPPHSQTSGSCYYHVISKVPRIRTPSYSPTQRSPGCRPLPSAGSPTPTTH EIVTVGDPLLSSGLRSIGSRRHSTSSLSPQRSKLRIMSPMRTGNTYSRNNVSSVSTTGTATDLESSAKVVDHVLGPLNSSTSLGQNTSTS SNLQRTVVTVGNKNSHLDGSSSSEMKQSSASDLVSKSSSLKGEKTKVLSSKSSEGSAHNVAYPGIPKLAPQVHNTTSRELNVSKIGSFAE PSSVSFSSKEALSFPHLHLRGQRNDRDQHTDSTQSANSSPDEDTEVKTLKLSGMSNRSSIINEHMGSSSRDRRQKGKKSCKETFKEKHSS KSFLEPGQVTTGEEGNLKPEFMDEVLTPEYMGQRPCNNVSSDKIGDKGLSMPGVPKAPPMQVEGSAKELQAPRKRTVKVTLTPLKMENES QSKNALKESSPASPLQIESTSPTEPISASENPGDGPVAQPSPNNTSCQDSQSNNYQNLPVQDRNLMLPDGPKPQEDGSFKRRYPRRSARA RSNMFFGLTPLYGVRSYGEEDIPFYSSSTGKKRGKRSAEGQVDGADDLSTSDEDDLYYYNFTRTVISSGGEERLASHNLFREEEQCDLPK ISQLDGVDDGTESDTSVTATTRKSSQIPKRNGKENGTENLKIDRPEDAGEKEHVTKSSVGHKNEPKMDNCHSVSRVKTQGQDSLEAQLSS LESSRRVHTSTPSDKNLLDTYNTELLKSDSDNNNSDDCGNILPSDIMDFVLKNTPSMQALGESPESSSSELLNLGEGLGLDSNREKDMGL FEVFSQQLPTTEPVDSSVSSSISAEEQFELPLELPSDLSVLTTRSPTVPSQNPSRLAVISDSGEKRVTITEKSVASSESDPALLSPGVDP TPEGHMTPDHFIQGHMDADHISSPPCGSVEQGHGNNQDLTRNSSTPGLQVPVSPTVPIQNQKYVPNSTDSPGPSQISNAAVQTTPPHLKP ATEKLIVVNQNMQPLYVLQTLPNGVTQKIQLTSSVSSTPSVMETNTSVLGPMGGGLTLTTGLNPSLPTSQSLFPSASKGLLPMSHHQHLH SFPAATQSSFPPNISNPPSGLLIGVQPPPDPQLLVSESSQRTDLSTTVATPSSGLKKRPISRLQTRKNKKLAPSSTPSNIAPSDVVSNMT LINFTPSQLPNHPSLLDLGSLNTSSHRTVPNIIKRSKSSIMYFEPAPLLPQSVGGTAATAAGTSTISQDTSHLTSGSVSGLASSSSVLNV VSMQTTTTPTSSASVPGHVTLTNPRLLGTPDIGSISNLLIKASQQSLGIQDQPVALPPSSGMFPQLGTSQTPSTAAITAASSICVLPSTQ TTGITAASPSGEADEHYQLQHVNQLLASKTGIHSSQRDLDSASGPQVSNFTQTVDAPNSMGLEQNKALSSAVQASPTSPGGSPSSPSSGQ RSASPSVPGPTKPKPKTKRFQLPLDKGNGKKHKVSHLRTSSSEAHIPDQETTSLTSGTGTPGAEAEQQDTASVEQSSQKECGQPAGQVAV LPEVQVTQNPANEQESAEPKTVEEEESNFSSPLMLWLQQEQKRKESITEKKPKKGLVFEISSDDGFQICAESIEDAWKSLTDKVQEARSN ARLKQLSFAGVNGLRMLGILHDAVVFLIEQLSGAKHCRNYKFRFHKPEEANEPPLNPHGSARAEVHLRKSAFDMFNFLASKHRQPPEYNP NDEEEEEVQLKSARRATSMDLPMPMRFRHLKKTSKEAVGVYRSPIHGRGLFCKRNIDAGEMVIEYAGNVIRSIQTDKREKYYDSKGIGCY -------------------------------------------------------------- >2660_2660_25_AFF1-KMT2A_AFF1_chr4_87968752_ENST00000307808_KMT2A_chr11_118359327_ENST00000354520_length(amino acids)=2871AA_BP=346 MAAQSSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKTAKGDELSSRIQNMLGNYEEVKEFLSTKSHTHRLDASENRLGKP KYPLIPDKGSSIPSSSFHTSVHHQSIHTPASGPLSVGNISHNPKMAQPRTEPMPSLHAKSCGPPDSQHLTQDRLGQEGFGSSHHKKGDRR ADGDHCASVTDSAPERELSPLISLPSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNNSKGYCPAKSPKDLAVKVHDKETPQDSLVAPAQPP SQTFPPPSLPSKSVAMQQKPTAYVRPMDGQDQAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEFVYCQVCCEPFHKF CLEENERPLEDQLENWCCRRCKFCHVCGRQHQATKQLLECNKCRNSYHPECLGPNYPTKPTKKKKVWICTKCVRCKSCGSTTPGKGWDAQ WSHDFSLCHDCAKLFAKGNFCPLCDKCYDDDDYESKMMQCGKCDRWVHSKCENLSDEMYEILSNLPESVAYTCVNCTERHPAEWRLALEK ELQISLKQVLTALLNSRTTSHLLRYRQAAKPPDLNPETEESIPSRSSPEGPDPPVLTEVSKQDDQQPLDLEGVKRKMDQGNYTSVLEFSD DIVKIIQAAINSDGGQPEIKKANSMVKSFFIRQMERVFPWFSVKKSRFWEPNKVSSNSGMLPNAVLPPSLDHNYAQWQEREENSHTEQPP LMKKIIPAPKPKGPGEPDSPTPLHPPTPPILSTDRSREDSPELNPPPGIEDNRQCALCLTYGDDSANDAGRLLYIGQNEWTHVNCALWSA EVFEDDDGSLKNVHMAVIRGKQLRCEFCQKPGATVGCCLTSCTSNYHFMCSRAKNCVFLDDKKVYCQRHRDLIKGEVVPENGFEVFRRVF VDFEGISLRRKFLNGLEPENIHMMIGSMTIDCLGILNDLSDCEDKLFPIGYQCSRVYWSTTDARKRCVYTCKIVECRPPVVEPDINSTVE HDENRTIAHSPTSFTESSSKESQNTAEIISPPSPDRPPHSQTSGSCYYHVISKVPRIRTPSYSPTQRSPGCRPLPSAGSPTPTTHEIVTV GDPLLSSGLRSIGSRRHSTSSLSPQRSKLRIMSPMRTGNTYSRNNVSSVSTTGTATDLESSAKVVDHVLGPLNSSTSLGQNTSTSSNLQR TVVTVGNKNSHLDGSSSSEMKQSSASDLVSKSSSLKGEKTKVLSSKSSEGSAHNVAYPGIPKLAPQVHNTTSRELNVSKIGSFAEPSSVS FSSKEALSFPHLHLRGQRNDRDQHTDSTQSANSSPDEDTEVKTLKLSGMSNRSSIINEHMGSSSRDRRQKGKKSCKETFKEKHSSKSFLE PGQVTTGEEGNLKPEFMDEVLTPEYMGQRPCNNVSSDKIGDKGLSMPGVPKAPPMQVEGSAKELQAPRKRTVKVTLTPLKMENESQSKNA LKESSPASPLQIESTSPTEPISASENPGDGPVAQPSPNNTSCQDSQSNNYQNLPVQDRNLMLPDGPKPQEDGSFKRRYPRRSARARSNMF FGLTPLYGVRSYGEEDIPFYSSSTGKKRGKRSAEGQVDGADDLSTSDEDDLYYYNFTRTVISSGGEERLASHNLFREEEQCDLPKISQLD GVDDGTESDTSVTATTRKSSQIPKRNGKENGTENLKIDRPEDAGEKEHVTKSSVGHKNEPKMDNCHSVSRVKTQGQDSLEAQLSSLESSR RVHTSTPSDKNLLDTYNTELLKSDSDNNNSDDCGNILPSDIMDFVLKNTPSMQALGESPESSSSELLNLGEGLGLDSNREKDMGLFEVFS QQLPTTEPVDSSVSSSISAEEQFELPLELPSDLSVLTTRSPTVPSQNPSRLAVISDSGEKRVTITEKSVASSESDPALLSPGVDPTPEGH MTPDHFIQGHMDADHISSPPCGSVEQGHGNNQDLTRNSSTPGLQVPVSPTVPIQNQKYVPNSTDSPGPSQISNAAVQTTPPHLKPATEKL IVVNQNMQPLYVLQTLPNGVTQKIQLTSSVSSTPSVMETNTSVLGPMGGGLTLTTGLNPSLPTSQSLFPSASKGLLPMSHHQHLHSFPAA TQSSFPPNISNPPSGLLIGVQPPPDPQLLVSESSQRTDLSTTVATPSSGLKKRPISRLQTRKNKKLAPSSTPSNIAPSDVVSNMTLINFT PSQLPNHPSLLDLGSLNTSSHRTVPNIIKRSKSSIMYFEPAPLLPQSVGGTAATAAGTSTISQDTSHLTSGSVSGLASSSSVLNVVSMQT TTTPTSSASVPGHVTLTNPRLLGTPDIGSISNLLIKASQQSLGIQDQPVALPPSSGMFPQLGTSQTPSTAAITAASSICVLPSTQTTGIT AASPSGEADEHYQLQHVNQLLASKTGIHSSQRDLDSASGPQVSNFTQTVDAPNSMGLEQNKALSSAVQASPTSPGGSPSSPSSGQRSASP SVPGPTKPKPKTKRFQLPLDKGNGKKHKVSHLRTSSSEAHIPDQETTSLTSGTGTPGAEAEQQDTASVEQSSQKECGQPAGQVAVLPEVQ VTQNPANEQESAEPKTVEEEESNFSSPLMLWLQQEQKRKESITEKKPKKGLVFEISSDDGFQICAESIEDAWKSLTDKVQEARSNARLKQ LSFAGVNGLRMLGILHDAVVFLIEQLSGAKHCRNYKFRFHKPEEANEPPLNPHGSARAEVHLRKSAFDMFNFLASKHRQPPEYNPNDEEE EEVQLKSARRATSMDLPMPMRFRHLKKTSKEAVGVYRSPIHGRGLFCKRNIDAGEMVIEYAGNVIRSIQTDKREKYYDSKGIGCYMFRID -------------------------------------------------------------- >2660_2660_26_AFF1-KMT2A_AFF1_chr4_87968752_ENST00000307808_KMT2A_chr11_118359327_ENST00000389506_length(amino acids)=2871AA_BP=346 MAAQSSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKTAKGDELSSRIQNMLGNYEEVKEFLSTKSHTHRLDASENRLGKP KYPLIPDKGSSIPSSSFHTSVHHQSIHTPASGPLSVGNISHNPKMAQPRTEPMPSLHAKSCGPPDSQHLTQDRLGQEGFGSSHHKKGDRR ADGDHCASVTDSAPERELSPLISLPSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNNSKGYCPAKSPKDLAVKVHDKETPQDSLVAPAQPP SQTFPPPSLPSKSVAMQQKPTAYVRPMDGQDQAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEFVYCQVCCEPFHKF CLEENERPLEDQLENWCCRRCKFCHVCGRQHQATKQLLECNKCRNSYHPECLGPNYPTKPTKKKKVWICTKCVRCKSCGSTTPGKGWDAQ WSHDFSLCHDCAKLFAKGNFCPLCDKCYDDDDYESKMMQCGKCDRWVHSKCENLSDEMYEILSNLPESVAYTCVNCTERHPAEWRLALEK ELQISLKQVLTALLNSRTTSHLLRYRQAAKPPDLNPETEESIPSRSSPEGPDPPVLTEVSKQDDQQPLDLEGVKRKMDQGNYTSVLEFSD DIVKIIQAAINSDGGQPEIKKANSMVKSFFIRQMERVFPWFSVKKSRFWEPNKVSSNSGMLPNAVLPPSLDHNYAQWQEREENSHTEQPP LMKKIIPAPKPKGPGEPDSPTPLHPPTPPILSTDRSREDSPELNPPPGIEDNRQCALCLTYGDDSANDAGRLLYIGQNEWTHVNCALWSA EVFEDDDGSLKNVHMAVIRGKQLRCEFCQKPGATVGCCLTSCTSNYHFMCSRAKNCVFLDDKKVYCQRHRDLIKGEVVPENGFEVFRRVF VDFEGISLRRKFLNGLEPENIHMMIGSMTIDCLGILNDLSDCEDKLFPIGYQCSRVYWSTTDARKRCVYTCKIVECRPPVVEPDINSTVE HDENRTIAHSPTSFTESSSKESQNTAEIISPPSPDRPPHSQTSGSCYYHVISKVPRIRTPSYSPTQRSPGCRPLPSAGSPTPTTHEIVTV GDPLLSSGLRSIGSRRHSTSSLSPQRSKLRIMSPMRTGNTYSRNNVSSVSTTGTATDLESSAKVVDHVLGPLNSSTSLGQNTSTSSNLQR TVVTVGNKNSHLDGSSSSEMKQSSASDLVSKSSSLKGEKTKVLSSKSSEGSAHNVAYPGIPKLAPQVHNTTSRELNVSKIGSFAEPSSVS FSSKEALSFPHLHLRGQRNDRDQHTDSTQSANSSPDEDTEVKTLKLSGMSNRSSIINEHMGSSSRDRRQKGKKSCKETFKEKHSSKSFLE PGQVTTGEEGNLKPEFMDEVLTPEYMGQRPCNNVSSDKIGDKGLSMPGVPKAPPMQVEGSAKELQAPRKRTVKVTLTPLKMENESQSKNA LKESSPASPLQIESTSPTEPISASENPGDGPVAQPSPNNTSCQDSQSNNYQNLPVQDRNLMLPDGPKPQEDGSFKRRYPRRSARARSNMF FGLTPLYGVRSYGEEDIPFYSSSTGKKRGKRSAEGQVDGADDLSTSDEDDLYYYNFTRTVISSGGEERLASHNLFREEEQCDLPKISQLD GVDDGTESDTSVTATTRKSSQIPKRNGKENGTENLKIDRPEDAGEKEHVTKSSVGHKNEPKMDNCHSVSRVKTQGQDSLEAQLSSLESSR RVHTSTPSDKNLLDTYNTELLKSDSDNNNSDDCGNILPSDIMDFVLKNTPSMQALGESPESSSSELLNLGEGLGLDSNREKDMGLFEVFS QQLPTTEPVDSSVSSSISAEEQFELPLELPSDLSVLTTRSPTVPSQNPSRLAVISDSGEKRVTITEKSVASSESDPALLSPGVDPTPEGH MTPDHFIQGHMDADHISSPPCGSVEQGHGNNQDLTRNSSTPGLQVPVSPTVPIQNQKYVPNSTDSPGPSQISNAAVQTTPPHLKPATEKL IVVNQNMQPLYVLQTLPNGVTQKIQLTSSVSSTPSVMETNTSVLGPMGGGLTLTTGLNPSLPTSQSLFPSASKGLLPMSHHQHLHSFPAA TQSSFPPNISNPPSGLLIGVQPPPDPQLLVSESSQRTDLSTTVATPSSGLKKRPISRLQTRKNKKLAPSSTPSNIAPSDVVSNMTLINFT PSQLPNHPSLLDLGSLNTSSHRTVPNIIKRSKSSIMYFEPAPLLPQSVGGTAATAAGTSTISQDTSHLTSGSVSGLASSSSVLNVVSMQT TTTPTSSASVPGHVTLTNPRLLGTPDIGSISNLLIKASQQSLGIQDQPVALPPSSGMFPQLGTSQTPSTAAITAASSICVLPSTQTTGIT AASPSGEADEHYQLQHVNQLLASKTGIHSSQRDLDSASGPQVSNFTQTVDAPNSMGLEQNKALSSAVQASPTSPGGSPSSPSSGQRSASP SVPGPTKPKPKTKRFQLPLDKGNGKKHKVSHLRTSSSEAHIPDQETTSLTSGTGTPGAEAEQQDTASVEQSSQKECGQPAGQVAVLPEVQ VTQNPANEQESAEPKTVEEEESNFSSPLMLWLQQEQKRKESITEKKPKKGLVFEISSDDGFQICAESIEDAWKSLTDKVQEARSNARLKQ LSFAGVNGLRMLGILHDAVVFLIEQLSGAKHCRNYKFRFHKPEEANEPPLNPHGSARAEVHLRKSAFDMFNFLASKHRQPPEYNPNDEEE EEVQLKSARRATSMDLPMPMRFRHLKKTSKEAVGVYRSPIHGRGLFCKRNIDAGEMVIEYAGNVIRSIQTDKREKYYDSKGIGCYMFRID -------------------------------------------------------------- >2660_2660_27_AFF1-KMT2A_AFF1_chr4_87968752_ENST00000307808_KMT2A_chr11_118359327_ENST00000534358_length(amino acids)=2874AA_BP=346 MAAQSSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKTAKGDELSSRIQNMLGNYEEVKEFLSTKSHTHRLDASENRLGKP KYPLIPDKGSSIPSSSFHTSVHHQSIHTPASGPLSVGNISHNPKMAQPRTEPMPSLHAKSCGPPDSQHLTQDRLGQEGFGSSHHKKGDRR ADGDHCASVTDSAPERELSPLISLPSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNNSKGYCPAKSPKDLAVKVHDKETPQDSLVAPAQPP SQTFPPPSLPSKSVAMQQKPTAYVRPMDGQDQAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEFVYCQVCCEPFHKF CLEENERPLEDQLENWCCRRCKFCHVCGRQHQATKQLLECNKCRNSYHPECLGPNYPTKPTKKKKVWICTKCVRCKSCGSTTPGKGWDAQ WSHDFSLCHDCAKLFAKGNFCPLCDKCYDDDDYESKMMQCGKCDRWVHSKCENLSGTEDEMYEILSNLPESVAYTCVNCTERHPAEWRLA LEKELQISLKQVLTALLNSRTTSHLLRYRQAAKPPDLNPETEESIPSRSSPEGPDPPVLTEVSKQDDQQPLDLEGVKRKMDQGNYTSVLE FSDDIVKIIQAAINSDGGQPEIKKANSMVKSFFIRQMERVFPWFSVKKSRFWEPNKVSSNSGMLPNAVLPPSLDHNYAQWQEREENSHTE QPPLMKKIIPAPKPKGPGEPDSPTPLHPPTPPILSTDRSREDSPELNPPPGIEDNRQCALCLTYGDDSANDAGRLLYIGQNEWTHVNCAL WSAEVFEDDDGSLKNVHMAVIRGKQLRCEFCQKPGATVGCCLTSCTSNYHFMCSRAKNCVFLDDKKVYCQRHRDLIKGEVVPENGFEVFR RVFVDFEGISLRRKFLNGLEPENIHMMIGSMTIDCLGILNDLSDCEDKLFPIGYQCSRVYWSTTDARKRCVYTCKIVECRPPVVEPDINS TVEHDENRTIAHSPTSFTESSSKESQNTAEIISPPSPDRPPHSQTSGSCYYHVISKVPRIRTPSYSPTQRSPGCRPLPSAGSPTPTTHEI VTVGDPLLSSGLRSIGSRRHSTSSLSPQRSKLRIMSPMRTGNTYSRNNVSSVSTTGTATDLESSAKVVDHVLGPLNSSTSLGQNTSTSSN LQRTVVTVGNKNSHLDGSSSSEMKQSSASDLVSKSSSLKGEKTKVLSSKSSEGSAHNVAYPGIPKLAPQVHNTTSRELNVSKIGSFAEPS SVSFSSKEALSFPHLHLRGQRNDRDQHTDSTQSANSSPDEDTEVKTLKLSGMSNRSSIINEHMGSSSRDRRQKGKKSCKETFKEKHSSKS FLEPGQVTTGEEGNLKPEFMDEVLTPEYMGQRPCNNVSSDKIGDKGLSMPGVPKAPPMQVEGSAKELQAPRKRTVKVTLTPLKMENESQS KNALKESSPASPLQIESTSPTEPISASENPGDGPVAQPSPNNTSCQDSQSNNYQNLPVQDRNLMLPDGPKPQEDGSFKRRYPRRSARARS NMFFGLTPLYGVRSYGEEDIPFYSSSTGKKRGKRSAEGQVDGADDLSTSDEDDLYYYNFTRTVISSGGEERLASHNLFREEEQCDLPKIS QLDGVDDGTESDTSVTATTRKSSQIPKRNGKENGTENLKIDRPEDAGEKEHVTKSSVGHKNEPKMDNCHSVSRVKTQGQDSLEAQLSSLE SSRRVHTSTPSDKNLLDTYNTELLKSDSDNNNSDDCGNILPSDIMDFVLKNTPSMQALGESPESSSSELLNLGEGLGLDSNREKDMGLFE VFSQQLPTTEPVDSSVSSSISAEEQFELPLELPSDLSVLTTRSPTVPSQNPSRLAVISDSGEKRVTITEKSVASSESDPALLSPGVDPTP EGHMTPDHFIQGHMDADHISSPPCGSVEQGHGNNQDLTRNSSTPGLQVPVSPTVPIQNQKYVPNSTDSPGPSQISNAAVQTTPPHLKPAT EKLIVVNQNMQPLYVLQTLPNGVTQKIQLTSSVSSTPSVMETNTSVLGPMGGGLTLTTGLNPSLPTSQSLFPSASKGLLPMSHHQHLHSF PAATQSSFPPNISNPPSGLLIGVQPPPDPQLLVSESSQRTDLSTTVATPSSGLKKRPISRLQTRKNKKLAPSSTPSNIAPSDVVSNMTLI NFTPSQLPNHPSLLDLGSLNTSSHRTVPNIIKRSKSSIMYFEPAPLLPQSVGGTAATAAGTSTISQDTSHLTSGSVSGLASSSSVLNVVS MQTTTTPTSSASVPGHVTLTNPRLLGTPDIGSISNLLIKASQQSLGIQDQPVALPPSSGMFPQLGTSQTPSTAAITAASSICVLPSTQTT GITAASPSGEADEHYQLQHVNQLLASKTGIHSSQRDLDSASGPQVSNFTQTVDAPNSMGLEQNKALSSAVQASPTSPGGSPSSPSSGQRS ASPSVPGPTKPKPKTKRFQLPLDKGNGKKHKVSHLRTSSSEAHIPDQETTSLTSGTGTPGAEAEQQDTASVEQSSQKECGQPAGQVAVLP EVQVTQNPANEQESAEPKTVEEEESNFSSPLMLWLQQEQKRKESITEKKPKKGLVFEISSDDGFQICAESIEDAWKSLTDKVQEARSNAR LKQLSFAGVNGLRMLGILHDAVVFLIEQLSGAKHCRNYKFRFHKPEEANEPPLNPHGSARAEVHLRKSAFDMFNFLASKHRQPPEYNPND EEEEEVQLKSARRATSMDLPMPMRFRHLKKTSKEAVGVYRSPIHGRGLFCKRNIDAGEMVIEYAGNVIRSIQTDKREKYYDSKGIGCYMF -------------------------------------------------------------- >2660_2660_28_AFF1-KMT2A_AFF1_chr4_87968752_ENST00000395146_KMT2A_chr11_118359327_ENST00000354520_length(amino acids)=2881AA_BP=356 METMAFTERVNSSGNSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKTAKGDELSSRIQNMLGNYEEVKEFLSTKSHTHRL DASENRLGKPKYPLIPDKGSSIPSSSFHTSVHHQSIHTPASGPLSVGNISHNPKMAQPRTEPMPSLHAKSCGPPDSQHLTQDRLGQEGFG SSHHKKGDRRADGDHCASVTDSAPERELSPLISLPSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNNSKGYCPAKSPKDLAVKVHDKETPQ DSLVAPAQPPSQTFPPPSLPSKSVAMQQKPTAYVRPMDGQDQAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEFVYC QVCCEPFHKFCLEENERPLEDQLENWCCRRCKFCHVCGRQHQATKQLLECNKCRNSYHPECLGPNYPTKPTKKKKVWICTKCVRCKSCGS TTPGKGWDAQWSHDFSLCHDCAKLFAKGNFCPLCDKCYDDDDYESKMMQCGKCDRWVHSKCENLSDEMYEILSNLPESVAYTCVNCTERH PAEWRLALEKELQISLKQVLTALLNSRTTSHLLRYRQAAKPPDLNPETEESIPSRSSPEGPDPPVLTEVSKQDDQQPLDLEGVKRKMDQG NYTSVLEFSDDIVKIIQAAINSDGGQPEIKKANSMVKSFFIRQMERVFPWFSVKKSRFWEPNKVSSNSGMLPNAVLPPSLDHNYAQWQER EENSHTEQPPLMKKIIPAPKPKGPGEPDSPTPLHPPTPPILSTDRSREDSPELNPPPGIEDNRQCALCLTYGDDSANDAGRLLYIGQNEW THVNCALWSAEVFEDDDGSLKNVHMAVIRGKQLRCEFCQKPGATVGCCLTSCTSNYHFMCSRAKNCVFLDDKKVYCQRHRDLIKGEVVPE NGFEVFRRVFVDFEGISLRRKFLNGLEPENIHMMIGSMTIDCLGILNDLSDCEDKLFPIGYQCSRVYWSTTDARKRCVYTCKIVECRPPV VEPDINSTVEHDENRTIAHSPTSFTESSSKESQNTAEIISPPSPDRPPHSQTSGSCYYHVISKVPRIRTPSYSPTQRSPGCRPLPSAGSP TPTTHEIVTVGDPLLSSGLRSIGSRRHSTSSLSPQRSKLRIMSPMRTGNTYSRNNVSSVSTTGTATDLESSAKVVDHVLGPLNSSTSLGQ NTSTSSNLQRTVVTVGNKNSHLDGSSSSEMKQSSASDLVSKSSSLKGEKTKVLSSKSSEGSAHNVAYPGIPKLAPQVHNTTSRELNVSKI GSFAEPSSVSFSSKEALSFPHLHLRGQRNDRDQHTDSTQSANSSPDEDTEVKTLKLSGMSNRSSIINEHMGSSSRDRRQKGKKSCKETFK EKHSSKSFLEPGQVTTGEEGNLKPEFMDEVLTPEYMGQRPCNNVSSDKIGDKGLSMPGVPKAPPMQVEGSAKELQAPRKRTVKVTLTPLK MENESQSKNALKESSPASPLQIESTSPTEPISASENPGDGPVAQPSPNNTSCQDSQSNNYQNLPVQDRNLMLPDGPKPQEDGSFKRRYPR RSARARSNMFFGLTPLYGVRSYGEEDIPFYSSSTGKKRGKRSAEGQVDGADDLSTSDEDDLYYYNFTRTVISSGGEERLASHNLFREEEQ CDLPKISQLDGVDDGTESDTSVTATTRKSSQIPKRNGKENGTENLKIDRPEDAGEKEHVTKSSVGHKNEPKMDNCHSVSRVKTQGQDSLE AQLSSLESSRRVHTSTPSDKNLLDTYNTELLKSDSDNNNSDDCGNILPSDIMDFVLKNTPSMQALGESPESSSSELLNLGEGLGLDSNRE KDMGLFEVFSQQLPTTEPVDSSVSSSISAEEQFELPLELPSDLSVLTTRSPTVPSQNPSRLAVISDSGEKRVTITEKSVASSESDPALLS PGVDPTPEGHMTPDHFIQGHMDADHISSPPCGSVEQGHGNNQDLTRNSSTPGLQVPVSPTVPIQNQKYVPNSTDSPGPSQISNAAVQTTP PHLKPATEKLIVVNQNMQPLYVLQTLPNGVTQKIQLTSSVSSTPSVMETNTSVLGPMGGGLTLTTGLNPSLPTSQSLFPSASKGLLPMSH HQHLHSFPAATQSSFPPNISNPPSGLLIGVQPPPDPQLLVSESSQRTDLSTTVATPSSGLKKRPISRLQTRKNKKLAPSSTPSNIAPSDV VSNMTLINFTPSQLPNHPSLLDLGSLNTSSHRTVPNIIKRSKSSIMYFEPAPLLPQSVGGTAATAAGTSTISQDTSHLTSGSVSGLASSS SVLNVVSMQTTTTPTSSASVPGHVTLTNPRLLGTPDIGSISNLLIKASQQSLGIQDQPVALPPSSGMFPQLGTSQTPSTAAITAASSICV LPSTQTTGITAASPSGEADEHYQLQHVNQLLASKTGIHSSQRDLDSASGPQVSNFTQTVDAPNSMGLEQNKALSSAVQASPTSPGGSPSS PSSGQRSASPSVPGPTKPKPKTKRFQLPLDKGNGKKHKVSHLRTSSSEAHIPDQETTSLTSGTGTPGAEAEQQDTASVEQSSQKECGQPA GQVAVLPEVQVTQNPANEQESAEPKTVEEEESNFSSPLMLWLQQEQKRKESITEKKPKKGLVFEISSDDGFQICAESIEDAWKSLTDKVQ EARSNARLKQLSFAGVNGLRMLGILHDAVVFLIEQLSGAKHCRNYKFRFHKPEEANEPPLNPHGSARAEVHLRKSAFDMFNFLASKHRQP PEYNPNDEEEEEVQLKSARRATSMDLPMPMRFRHLKKTSKEAVGVYRSPIHGRGLFCKRNIDAGEMVIEYAGNVIRSIQTDKREKYYDSK GIGCYMFRIDDSEVVDATMHGNAARFINHSCEPNCYSRVINIDGQKHIVIFAMRKIYRGEELTYDYKFPIEDASNKLPCNCGAKKCRKFL -------------------------------------------------------------- >2660_2660_29_AFF1-KMT2A_AFF1_chr4_87968752_ENST00000395146_KMT2A_chr11_118359327_ENST00000389506_length(amino acids)=2881AA_BP=356 METMAFTERVNSSGNSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKTAKGDELSSRIQNMLGNYEEVKEFLSTKSHTHRL DASENRLGKPKYPLIPDKGSSIPSSSFHTSVHHQSIHTPASGPLSVGNISHNPKMAQPRTEPMPSLHAKSCGPPDSQHLTQDRLGQEGFG SSHHKKGDRRADGDHCASVTDSAPERELSPLISLPSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNNSKGYCPAKSPKDLAVKVHDKETPQ DSLVAPAQPPSQTFPPPSLPSKSVAMQQKPTAYVRPMDGQDQAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEFVYC QVCCEPFHKFCLEENERPLEDQLENWCCRRCKFCHVCGRQHQATKQLLECNKCRNSYHPECLGPNYPTKPTKKKKVWICTKCVRCKSCGS TTPGKGWDAQWSHDFSLCHDCAKLFAKGNFCPLCDKCYDDDDYESKMMQCGKCDRWVHSKCENLSDEMYEILSNLPESVAYTCVNCTERH PAEWRLALEKELQISLKQVLTALLNSRTTSHLLRYRQAAKPPDLNPETEESIPSRSSPEGPDPPVLTEVSKQDDQQPLDLEGVKRKMDQG NYTSVLEFSDDIVKIIQAAINSDGGQPEIKKANSMVKSFFIRQMERVFPWFSVKKSRFWEPNKVSSNSGMLPNAVLPPSLDHNYAQWQER EENSHTEQPPLMKKIIPAPKPKGPGEPDSPTPLHPPTPPILSTDRSREDSPELNPPPGIEDNRQCALCLTYGDDSANDAGRLLYIGQNEW THVNCALWSAEVFEDDDGSLKNVHMAVIRGKQLRCEFCQKPGATVGCCLTSCTSNYHFMCSRAKNCVFLDDKKVYCQRHRDLIKGEVVPE NGFEVFRRVFVDFEGISLRRKFLNGLEPENIHMMIGSMTIDCLGILNDLSDCEDKLFPIGYQCSRVYWSTTDARKRCVYTCKIVECRPPV VEPDINSTVEHDENRTIAHSPTSFTESSSKESQNTAEIISPPSPDRPPHSQTSGSCYYHVISKVPRIRTPSYSPTQRSPGCRPLPSAGSP TPTTHEIVTVGDPLLSSGLRSIGSRRHSTSSLSPQRSKLRIMSPMRTGNTYSRNNVSSVSTTGTATDLESSAKVVDHVLGPLNSSTSLGQ NTSTSSNLQRTVVTVGNKNSHLDGSSSSEMKQSSASDLVSKSSSLKGEKTKVLSSKSSEGSAHNVAYPGIPKLAPQVHNTTSRELNVSKI GSFAEPSSVSFSSKEALSFPHLHLRGQRNDRDQHTDSTQSANSSPDEDTEVKTLKLSGMSNRSSIINEHMGSSSRDRRQKGKKSCKETFK EKHSSKSFLEPGQVTTGEEGNLKPEFMDEVLTPEYMGQRPCNNVSSDKIGDKGLSMPGVPKAPPMQVEGSAKELQAPRKRTVKVTLTPLK MENESQSKNALKESSPASPLQIESTSPTEPISASENPGDGPVAQPSPNNTSCQDSQSNNYQNLPVQDRNLMLPDGPKPQEDGSFKRRYPR RSARARSNMFFGLTPLYGVRSYGEEDIPFYSSSTGKKRGKRSAEGQVDGADDLSTSDEDDLYYYNFTRTVISSGGEERLASHNLFREEEQ CDLPKISQLDGVDDGTESDTSVTATTRKSSQIPKRNGKENGTENLKIDRPEDAGEKEHVTKSSVGHKNEPKMDNCHSVSRVKTQGQDSLE AQLSSLESSRRVHTSTPSDKNLLDTYNTELLKSDSDNNNSDDCGNILPSDIMDFVLKNTPSMQALGESPESSSSELLNLGEGLGLDSNRE KDMGLFEVFSQQLPTTEPVDSSVSSSISAEEQFELPLELPSDLSVLTTRSPTVPSQNPSRLAVISDSGEKRVTITEKSVASSESDPALLS PGVDPTPEGHMTPDHFIQGHMDADHISSPPCGSVEQGHGNNQDLTRNSSTPGLQVPVSPTVPIQNQKYVPNSTDSPGPSQISNAAVQTTP PHLKPATEKLIVVNQNMQPLYVLQTLPNGVTQKIQLTSSVSSTPSVMETNTSVLGPMGGGLTLTTGLNPSLPTSQSLFPSASKGLLPMSH HQHLHSFPAATQSSFPPNISNPPSGLLIGVQPPPDPQLLVSESSQRTDLSTTVATPSSGLKKRPISRLQTRKNKKLAPSSTPSNIAPSDV VSNMTLINFTPSQLPNHPSLLDLGSLNTSSHRTVPNIIKRSKSSIMYFEPAPLLPQSVGGTAATAAGTSTISQDTSHLTSGSVSGLASSS SVLNVVSMQTTTTPTSSASVPGHVTLTNPRLLGTPDIGSISNLLIKASQQSLGIQDQPVALPPSSGMFPQLGTSQTPSTAAITAASSICV LPSTQTTGITAASPSGEADEHYQLQHVNQLLASKTGIHSSQRDLDSASGPQVSNFTQTVDAPNSMGLEQNKALSSAVQASPTSPGGSPSS PSSGQRSASPSVPGPTKPKPKTKRFQLPLDKGNGKKHKVSHLRTSSSEAHIPDQETTSLTSGTGTPGAEAEQQDTASVEQSSQKECGQPA GQVAVLPEVQVTQNPANEQESAEPKTVEEEESNFSSPLMLWLQQEQKRKESITEKKPKKGLVFEISSDDGFQICAESIEDAWKSLTDKVQ EARSNARLKQLSFAGVNGLRMLGILHDAVVFLIEQLSGAKHCRNYKFRFHKPEEANEPPLNPHGSARAEVHLRKSAFDMFNFLASKHRQP PEYNPNDEEEEEVQLKSARRATSMDLPMPMRFRHLKKTSKEAVGVYRSPIHGRGLFCKRNIDAGEMVIEYAGNVIRSIQTDKREKYYDSK GIGCYMFRIDDSEVVDATMHGNAARFINHSCEPNCYSRVINIDGQKHIVIFAMRKIYRGEELTYDYKFPIEDASNKLPCNCGAKKCRKFL -------------------------------------------------------------- >2660_2660_30_AFF1-KMT2A_AFF1_chr4_87968752_ENST00000395146_KMT2A_chr11_118359327_ENST00000534358_length(amino acids)=2884AA_BP=356 METMAFTERVNSSGNSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKTAKGDELSSRIQNMLGNYEEVKEFLSTKSHTHRL DASENRLGKPKYPLIPDKGSSIPSSSFHTSVHHQSIHTPASGPLSVGNISHNPKMAQPRTEPMPSLHAKSCGPPDSQHLTQDRLGQEGFG SSHHKKGDRRADGDHCASVTDSAPERELSPLISLPSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNNSKGYCPAKSPKDLAVKVHDKETPQ DSLVAPAQPPSQTFPPPSLPSKSVAMQQKPTAYVRPMDGQDQAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEFVYC QVCCEPFHKFCLEENERPLEDQLENWCCRRCKFCHVCGRQHQATKQLLECNKCRNSYHPECLGPNYPTKPTKKKKVWICTKCVRCKSCGS TTPGKGWDAQWSHDFSLCHDCAKLFAKGNFCPLCDKCYDDDDYESKMMQCGKCDRWVHSKCENLSGTEDEMYEILSNLPESVAYTCVNCT ERHPAEWRLALEKELQISLKQVLTALLNSRTTSHLLRYRQAAKPPDLNPETEESIPSRSSPEGPDPPVLTEVSKQDDQQPLDLEGVKRKM DQGNYTSVLEFSDDIVKIIQAAINSDGGQPEIKKANSMVKSFFIRQMERVFPWFSVKKSRFWEPNKVSSNSGMLPNAVLPPSLDHNYAQW QEREENSHTEQPPLMKKIIPAPKPKGPGEPDSPTPLHPPTPPILSTDRSREDSPELNPPPGIEDNRQCALCLTYGDDSANDAGRLLYIGQ NEWTHVNCALWSAEVFEDDDGSLKNVHMAVIRGKQLRCEFCQKPGATVGCCLTSCTSNYHFMCSRAKNCVFLDDKKVYCQRHRDLIKGEV VPENGFEVFRRVFVDFEGISLRRKFLNGLEPENIHMMIGSMTIDCLGILNDLSDCEDKLFPIGYQCSRVYWSTTDARKRCVYTCKIVECR PPVVEPDINSTVEHDENRTIAHSPTSFTESSSKESQNTAEIISPPSPDRPPHSQTSGSCYYHVISKVPRIRTPSYSPTQRSPGCRPLPSA GSPTPTTHEIVTVGDPLLSSGLRSIGSRRHSTSSLSPQRSKLRIMSPMRTGNTYSRNNVSSVSTTGTATDLESSAKVVDHVLGPLNSSTS LGQNTSTSSNLQRTVVTVGNKNSHLDGSSSSEMKQSSASDLVSKSSSLKGEKTKVLSSKSSEGSAHNVAYPGIPKLAPQVHNTTSRELNV SKIGSFAEPSSVSFSSKEALSFPHLHLRGQRNDRDQHTDSTQSANSSPDEDTEVKTLKLSGMSNRSSIINEHMGSSSRDRRQKGKKSCKE TFKEKHSSKSFLEPGQVTTGEEGNLKPEFMDEVLTPEYMGQRPCNNVSSDKIGDKGLSMPGVPKAPPMQVEGSAKELQAPRKRTVKVTLT PLKMENESQSKNALKESSPASPLQIESTSPTEPISASENPGDGPVAQPSPNNTSCQDSQSNNYQNLPVQDRNLMLPDGPKPQEDGSFKRR YPRRSARARSNMFFGLTPLYGVRSYGEEDIPFYSSSTGKKRGKRSAEGQVDGADDLSTSDEDDLYYYNFTRTVISSGGEERLASHNLFRE EEQCDLPKISQLDGVDDGTESDTSVTATTRKSSQIPKRNGKENGTENLKIDRPEDAGEKEHVTKSSVGHKNEPKMDNCHSVSRVKTQGQD SLEAQLSSLESSRRVHTSTPSDKNLLDTYNTELLKSDSDNNNSDDCGNILPSDIMDFVLKNTPSMQALGESPESSSSELLNLGEGLGLDS NREKDMGLFEVFSQQLPTTEPVDSSVSSSISAEEQFELPLELPSDLSVLTTRSPTVPSQNPSRLAVISDSGEKRVTITEKSVASSESDPA LLSPGVDPTPEGHMTPDHFIQGHMDADHISSPPCGSVEQGHGNNQDLTRNSSTPGLQVPVSPTVPIQNQKYVPNSTDSPGPSQISNAAVQ TTPPHLKPATEKLIVVNQNMQPLYVLQTLPNGVTQKIQLTSSVSSTPSVMETNTSVLGPMGGGLTLTTGLNPSLPTSQSLFPSASKGLLP MSHHQHLHSFPAATQSSFPPNISNPPSGLLIGVQPPPDPQLLVSESSQRTDLSTTVATPSSGLKKRPISRLQTRKNKKLAPSSTPSNIAP SDVVSNMTLINFTPSQLPNHPSLLDLGSLNTSSHRTVPNIIKRSKSSIMYFEPAPLLPQSVGGTAATAAGTSTISQDTSHLTSGSVSGLA SSSSVLNVVSMQTTTTPTSSASVPGHVTLTNPRLLGTPDIGSISNLLIKASQQSLGIQDQPVALPPSSGMFPQLGTSQTPSTAAITAASS ICVLPSTQTTGITAASPSGEADEHYQLQHVNQLLASKTGIHSSQRDLDSASGPQVSNFTQTVDAPNSMGLEQNKALSSAVQASPTSPGGS PSSPSSGQRSASPSVPGPTKPKPKTKRFQLPLDKGNGKKHKVSHLRTSSSEAHIPDQETTSLTSGTGTPGAEAEQQDTASVEQSSQKECG QPAGQVAVLPEVQVTQNPANEQESAEPKTVEEEESNFSSPLMLWLQQEQKRKESITEKKPKKGLVFEISSDDGFQICAESIEDAWKSLTD KVQEARSNARLKQLSFAGVNGLRMLGILHDAVVFLIEQLSGAKHCRNYKFRFHKPEEANEPPLNPHGSARAEVHLRKSAFDMFNFLASKH RQPPEYNPNDEEEEEVQLKSARRATSMDLPMPMRFRHLKKTSKEAVGVYRSPIHGRGLFCKRNIDAGEMVIEYAGNVIRSIQTDKREKYY DSKGIGCYMFRIDDSEVVDATMHGNAARFINHSCEPNCYSRVINIDGQKHIVIFAMRKIYRGEELTYDYKFPIEDASNKLPCNCGAKKCR -------------------------------------------------------------- >2660_2660_31_AFF1-KMT2A_AFF1_chr4_88005317_ENST00000307808_KMT2A_chr11_118354896_ENST00000354520_length(amino acids)=2930AA_BP=361 MAAQSSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKTAKGDELSSRIQNMLGNYEEVKEFLSTKSHTHRLDASENRLGKP KYPLIPDKGSSIPSSSFHTSVHHQSIHTPASGPLSVGNISHNPKMAQPRTEPMPSLHAKSCGPPDSQHLTQDRLGQEGFGSSHHKKGDRR ADGDHCASVTDSAPERELSPLISLPSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNNSKGYCPAKSPKDLAVKVHDKETPQDSLVAPAQPP SQTFPPPSLPSKSVAMQQKPTAYVRPMDGQDQAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYSNEVHCVEEIL KEKPPPVNKQENAGTLNILSTLSNGNSSKQKIPADGVHRIRVDFKFVYCQVCCEPFHKFCLEENERPLEDQLENWCCRRCKFCHVCGRQH QATKQLLECNKCRNSYHPECLGPNYPTKPTKKKKVWICTKCVRCKSCGSTTPGKGWDAQWSHDFSLCHDCAKLFAKGNFCPLCDKCYDDD DYESKMMQCGKCDRWVHSKCENLSDEMYEILSNLPESVAYTCVNCTERHPAEWRLALEKELQISLKQVLTALLNSRTTSHLLRYRQAAKP PDLNPETEESIPSRSSPEGPDPPVLTEVSKQDDQQPLDLEGVKRKMDQGNYTSVLEFSDDIVKIIQAAINSDGGQPEIKKANSMVKSFFI RQMERVFPWFSVKKSRFWEPNKVSSNSGMLPNAVLPPSLDHNYAQWQEREENSHTEQPPLMKKIIPAPKPKGPGEPDSPTPLHPPTPPIL STDRSREDSPELNPPPGIEDNRQCALCLTYGDDSANDAGRLLYIGQNEWTHVNCALWSAEVFEDDDGSLKNVHMAVIRGKQLRCEFCQKP GATVGCCLTSCTSNYHFMCSRAKNCVFLDDKKVYCQRHRDLIKGEVVPENGFEVFRRVFVDFEGISLRRKFLNGLEPENIHMMIGSMTID CLGILNDLSDCEDKLFPIGYQCSRVYWSTTDARKRCVYTCKIVECRPPVVEPDINSTVEHDENRTIAHSPTSFTESSSKESQNTAEIISP PSPDRPPHSQTSGSCYYHVISKVPRIRTPSYSPTQRSPGCRPLPSAGSPTPTTHEIVTVGDPLLSSGLRSIGSRRHSTSSLSPQRSKLRI MSPMRTGNTYSRNNVSSVSTTGTATDLESSAKVVDHVLGPLNSSTSLGQNTSTSSNLQRTVVTVGNKNSHLDGSSSSEMKQSSASDLVSK SSSLKGEKTKVLSSKSSEGSAHNVAYPGIPKLAPQVHNTTSRELNVSKIGSFAEPSSVSFSSKEALSFPHLHLRGQRNDRDQHTDSTQSA NSSPDEDTEVKTLKLSGMSNRSSIINEHMGSSSRDRRQKGKKSCKETFKEKHSSKSFLEPGQVTTGEEGNLKPEFMDEVLTPEYMGQRPC NNVSSDKIGDKGLSMPGVPKAPPMQVEGSAKELQAPRKRTVKVTLTPLKMENESQSKNALKESSPASPLQIESTSPTEPISASENPGDGP VAQPSPNNTSCQDSQSNNYQNLPVQDRNLMLPDGPKPQEDGSFKRRYPRRSARARSNMFFGLTPLYGVRSYGEEDIPFYSSSTGKKRGKR SAEGQVDGADDLSTSDEDDLYYYNFTRTVISSGGEERLASHNLFREEEQCDLPKISQLDGVDDGTESDTSVTATTRKSSQIPKRNGKENG TENLKIDRPEDAGEKEHVTKSSVGHKNEPKMDNCHSVSRVKTQGQDSLEAQLSSLESSRRVHTSTPSDKNLLDTYNTELLKSDSDNNNSD DCGNILPSDIMDFVLKNTPSMQALGESPESSSSELLNLGEGLGLDSNREKDMGLFEVFSQQLPTTEPVDSSVSSSISAEEQFELPLELPS DLSVLTTRSPTVPSQNPSRLAVISDSGEKRVTITEKSVASSESDPALLSPGVDPTPEGHMTPDHFIQGHMDADHISSPPCGSVEQGHGNN QDLTRNSSTPGLQVPVSPTVPIQNQKYVPNSTDSPGPSQISNAAVQTTPPHLKPATEKLIVVNQNMQPLYVLQTLPNGVTQKIQLTSSVS STPSVMETNTSVLGPMGGGLTLTTGLNPSLPTSQSLFPSASKGLLPMSHHQHLHSFPAATQSSFPPNISNPPSGLLIGVQPPPDPQLLVS ESSQRTDLSTTVATPSSGLKKRPISRLQTRKNKKLAPSSTPSNIAPSDVVSNMTLINFTPSQLPNHPSLLDLGSLNTSSHRTVPNIIKRS KSSIMYFEPAPLLPQSVGGTAATAAGTSTISQDTSHLTSGSVSGLASSSSVLNVVSMQTTTTPTSSASVPGHVTLTNPRLLGTPDIGSIS NLLIKASQQSLGIQDQPVALPPSSGMFPQLGTSQTPSTAAITAASSICVLPSTQTTGITAASPSGEADEHYQLQHVNQLLASKTGIHSSQ RDLDSASGPQVSNFTQTVDAPNSMGLEQNKALSSAVQASPTSPGGSPSSPSSGQRSASPSVPGPTKPKPKTKRFQLPLDKGNGKKHKVSH LRTSSSEAHIPDQETTSLTSGTGTPGAEAEQQDTASVEQSSQKECGQPAGQVAVLPEVQVTQNPANEQESAEPKTVEEEESNFSSPLMLW LQQEQKRKESITEKKPKKGLVFEISSDDGFQICAESIEDAWKSLTDKVQEARSNARLKQLSFAGVNGLRMLGILHDAVVFLIEQLSGAKH CRNYKFRFHKPEEANEPPLNPHGSARAEVHLRKSAFDMFNFLASKHRQPPEYNPNDEEEEEVQLKSARRATSMDLPMPMRFRHLKKTSKE AVGVYRSPIHGRGLFCKRNIDAGEMVIEYAGNVIRSIQTDKREKYYDSKGIGCYMFRIDDSEVVDATMHGNAARFINHSCEPNCYSRVIN -------------------------------------------------------------- >2660_2660_32_AFF1-KMT2A_AFF1_chr4_88005317_ENST00000307808_KMT2A_chr11_118354896_ENST00000389506_length(amino acids)=2968AA_BP=361 MAAQSSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKTAKGDELSSRIQNMLGNYEEVKEFLSTKSHTHRLDASENRLGKP KYPLIPDKGSSIPSSSFHTSVHHQSIHTPASGPLSVGNISHNPKMAQPRTEPMPSLHAKSCGPPDSQHLTQDRLGQEGFGSSHHKKGDRR ADGDHCASVTDSAPERELSPLISLPSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNNSKGYCPAKSPKDLAVKVHDKETPQDSLVAPAQPP SQTFPPPSLPSKSVAMQQKPTAYVRPMDGQDQAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYSNEVHCVEEIL KEKPPPVNKQENAGTLNILSTLSNGNSSKQKIPADGVHRIRVDFKEDCEAENVWEMGGLGILTSVPITPRVVCFLCASSGHVEFVYCQVC CEPFHKFCLEENERPLEDQLENWCCRRCKFCHVCGRQHQATKQLLECNKCRNSYHPECLGPNYPTKPTKKKKVWICTKCVRCKSCGSTTP GKGWDAQWSHDFSLCHDCAKLFAKGNFCPLCDKCYDDDDYESKMMQCGKCDRWVHSKCENLSDEMYEILSNLPESVAYTCVNCTERHPAE WRLALEKELQISLKQVLTALLNSRTTSHLLRYRQAAKPPDLNPETEESIPSRSSPEGPDPPVLTEVSKQDDQQPLDLEGVKRKMDQGNYT SVLEFSDDIVKIIQAAINSDGGQPEIKKANSMVKSFFIRQMERVFPWFSVKKSRFWEPNKVSSNSGMLPNAVLPPSLDHNYAQWQEREEN SHTEQPPLMKKIIPAPKPKGPGEPDSPTPLHPPTPPILSTDRSREDSPELNPPPGIEDNRQCALCLTYGDDSANDAGRLLYIGQNEWTHV NCALWSAEVFEDDDGSLKNVHMAVIRGKQLRCEFCQKPGATVGCCLTSCTSNYHFMCSRAKNCVFLDDKKVYCQRHRDLIKGEVVPENGF EVFRRVFVDFEGISLRRKFLNGLEPENIHMMIGSMTIDCLGILNDLSDCEDKLFPIGYQCSRVYWSTTDARKRCVYTCKIVECRPPVVEP DINSTVEHDENRTIAHSPTSFTESSSKESQNTAEIISPPSPDRPPHSQTSGSCYYHVISKVPRIRTPSYSPTQRSPGCRPLPSAGSPTPT THEIVTVGDPLLSSGLRSIGSRRHSTSSLSPQRSKLRIMSPMRTGNTYSRNNVSSVSTTGTATDLESSAKVVDHVLGPLNSSTSLGQNTS TSSNLQRTVVTVGNKNSHLDGSSSSEMKQSSASDLVSKSSSLKGEKTKVLSSKSSEGSAHNVAYPGIPKLAPQVHNTTSRELNVSKIGSF AEPSSVSFSSKEALSFPHLHLRGQRNDRDQHTDSTQSANSSPDEDTEVKTLKLSGMSNRSSIINEHMGSSSRDRRQKGKKSCKETFKEKH SSKSFLEPGQVTTGEEGNLKPEFMDEVLTPEYMGQRPCNNVSSDKIGDKGLSMPGVPKAPPMQVEGSAKELQAPRKRTVKVTLTPLKMEN ESQSKNALKESSPASPLQIESTSPTEPISASENPGDGPVAQPSPNNTSCQDSQSNNYQNLPVQDRNLMLPDGPKPQEDGSFKRRYPRRSA RARSNMFFGLTPLYGVRSYGEEDIPFYSSSTGKKRGKRSAEGQVDGADDLSTSDEDDLYYYNFTRTVISSGGEERLASHNLFREEEQCDL PKISQLDGVDDGTESDTSVTATTRKSSQIPKRNGKENGTENLKIDRPEDAGEKEHVTKSSVGHKNEPKMDNCHSVSRVKTQGQDSLEAQL SSLESSRRVHTSTPSDKNLLDTYNTELLKSDSDNNNSDDCGNILPSDIMDFVLKNTPSMQALGESPESSSSELLNLGEGLGLDSNREKDM GLFEVFSQQLPTTEPVDSSVSSSISAEEQFELPLELPSDLSVLTTRSPTVPSQNPSRLAVISDSGEKRVTITEKSVASSESDPALLSPGV DPTPEGHMTPDHFIQGHMDADHISSPPCGSVEQGHGNNQDLTRNSSTPGLQVPVSPTVPIQNQKYVPNSTDSPGPSQISNAAVQTTPPHL KPATEKLIVVNQNMQPLYVLQTLPNGVTQKIQLTSSVSSTPSVMETNTSVLGPMGGGLTLTTGLNPSLPTSQSLFPSASKGLLPMSHHQH LHSFPAATQSSFPPNISNPPSGLLIGVQPPPDPQLLVSESSQRTDLSTTVATPSSGLKKRPISRLQTRKNKKLAPSSTPSNIAPSDVVSN MTLINFTPSQLPNHPSLLDLGSLNTSSHRTVPNIIKRSKSSIMYFEPAPLLPQSVGGTAATAAGTSTISQDTSHLTSGSVSGLASSSSVL NVVSMQTTTTPTSSASVPGHVTLTNPRLLGTPDIGSISNLLIKASQQSLGIQDQPVALPPSSGMFPQLGTSQTPSTAAITAASSICVLPS TQTTGITAASPSGEADEHYQLQHVNQLLASKTGIHSSQRDLDSASGPQVSNFTQTVDAPNSMGLEQNKALSSAVQASPTSPGGSPSSPSS GQRSASPSVPGPTKPKPKTKRFQLPLDKGNGKKHKVSHLRTSSSEAHIPDQETTSLTSGTGTPGAEAEQQDTASVEQSSQKECGQPAGQV AVLPEVQVTQNPANEQESAEPKTVEEEESNFSSPLMLWLQQEQKRKESITEKKPKKGLVFEISSDDGFQICAESIEDAWKSLTDKVQEAR SNARLKQLSFAGVNGLRMLGILHDAVVFLIEQLSGAKHCRNYKFRFHKPEEANEPPLNPHGSARAEVHLRKSAFDMFNFLASKHRQPPEY NPNDEEEEEVQLKSARRATSMDLPMPMRFRHLKKTSKEAVGVYRSPIHGRGLFCKRNIDAGEMVIEYAGNVIRSIQTDKREKYYDSKGIG -------------------------------------------------------------- >2660_2660_33_AFF1-KMT2A_AFF1_chr4_88005317_ENST00000307808_KMT2A_chr11_118354896_ENST00000534358_length(amino acids)=2971AA_BP=361 MAAQSSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKTAKGDELSSRIQNMLGNYEEVKEFLSTKSHTHRLDASENRLGKP KYPLIPDKGSSIPSSSFHTSVHHQSIHTPASGPLSVGNISHNPKMAQPRTEPMPSLHAKSCGPPDSQHLTQDRLGQEGFGSSHHKKGDRR ADGDHCASVTDSAPERELSPLISLPSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNNSKGYCPAKSPKDLAVKVHDKETPQDSLVAPAQPP SQTFPPPSLPSKSVAMQQKPTAYVRPMDGQDQAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYSNEVHCVEEIL KEKPPPVNKQENAGTLNILSTLSNGNSSKQKIPADGVHRIRVDFKEDCEAENVWEMGGLGILTSVPITPRVVCFLCASSGHVEFVYCQVC CEPFHKFCLEENERPLEDQLENWCCRRCKFCHVCGRQHQATKQLLECNKCRNSYHPECLGPNYPTKPTKKKKVWICTKCVRCKSCGSTTP GKGWDAQWSHDFSLCHDCAKLFAKGNFCPLCDKCYDDDDYESKMMQCGKCDRWVHSKCENLSGTEDEMYEILSNLPESVAYTCVNCTERH PAEWRLALEKELQISLKQVLTALLNSRTTSHLLRYRQAAKPPDLNPETEESIPSRSSPEGPDPPVLTEVSKQDDQQPLDLEGVKRKMDQG NYTSVLEFSDDIVKIIQAAINSDGGQPEIKKANSMVKSFFIRQMERVFPWFSVKKSRFWEPNKVSSNSGMLPNAVLPPSLDHNYAQWQER EENSHTEQPPLMKKIIPAPKPKGPGEPDSPTPLHPPTPPILSTDRSREDSPELNPPPGIEDNRQCALCLTYGDDSANDAGRLLYIGQNEW THVNCALWSAEVFEDDDGSLKNVHMAVIRGKQLRCEFCQKPGATVGCCLTSCTSNYHFMCSRAKNCVFLDDKKVYCQRHRDLIKGEVVPE NGFEVFRRVFVDFEGISLRRKFLNGLEPENIHMMIGSMTIDCLGILNDLSDCEDKLFPIGYQCSRVYWSTTDARKRCVYTCKIVECRPPV VEPDINSTVEHDENRTIAHSPTSFTESSSKESQNTAEIISPPSPDRPPHSQTSGSCYYHVISKVPRIRTPSYSPTQRSPGCRPLPSAGSP TPTTHEIVTVGDPLLSSGLRSIGSRRHSTSSLSPQRSKLRIMSPMRTGNTYSRNNVSSVSTTGTATDLESSAKVVDHVLGPLNSSTSLGQ NTSTSSNLQRTVVTVGNKNSHLDGSSSSEMKQSSASDLVSKSSSLKGEKTKVLSSKSSEGSAHNVAYPGIPKLAPQVHNTTSRELNVSKI GSFAEPSSVSFSSKEALSFPHLHLRGQRNDRDQHTDSTQSANSSPDEDTEVKTLKLSGMSNRSSIINEHMGSSSRDRRQKGKKSCKETFK EKHSSKSFLEPGQVTTGEEGNLKPEFMDEVLTPEYMGQRPCNNVSSDKIGDKGLSMPGVPKAPPMQVEGSAKELQAPRKRTVKVTLTPLK MENESQSKNALKESSPASPLQIESTSPTEPISASENPGDGPVAQPSPNNTSCQDSQSNNYQNLPVQDRNLMLPDGPKPQEDGSFKRRYPR RSARARSNMFFGLTPLYGVRSYGEEDIPFYSSSTGKKRGKRSAEGQVDGADDLSTSDEDDLYYYNFTRTVISSGGEERLASHNLFREEEQ CDLPKISQLDGVDDGTESDTSVTATTRKSSQIPKRNGKENGTENLKIDRPEDAGEKEHVTKSSVGHKNEPKMDNCHSVSRVKTQGQDSLE AQLSSLESSRRVHTSTPSDKNLLDTYNTELLKSDSDNNNSDDCGNILPSDIMDFVLKNTPSMQALGESPESSSSELLNLGEGLGLDSNRE KDMGLFEVFSQQLPTTEPVDSSVSSSISAEEQFELPLELPSDLSVLTTRSPTVPSQNPSRLAVISDSGEKRVTITEKSVASSESDPALLS PGVDPTPEGHMTPDHFIQGHMDADHISSPPCGSVEQGHGNNQDLTRNSSTPGLQVPVSPTVPIQNQKYVPNSTDSPGPSQISNAAVQTTP PHLKPATEKLIVVNQNMQPLYVLQTLPNGVTQKIQLTSSVSSTPSVMETNTSVLGPMGGGLTLTTGLNPSLPTSQSLFPSASKGLLPMSH HQHLHSFPAATQSSFPPNISNPPSGLLIGVQPPPDPQLLVSESSQRTDLSTTVATPSSGLKKRPISRLQTRKNKKLAPSSTPSNIAPSDV VSNMTLINFTPSQLPNHPSLLDLGSLNTSSHRTVPNIIKRSKSSIMYFEPAPLLPQSVGGTAATAAGTSTISQDTSHLTSGSVSGLASSS SVLNVVSMQTTTTPTSSASVPGHVTLTNPRLLGTPDIGSISNLLIKASQQSLGIQDQPVALPPSSGMFPQLGTSQTPSTAAITAASSICV LPSTQTTGITAASPSGEADEHYQLQHVNQLLASKTGIHSSQRDLDSASGPQVSNFTQTVDAPNSMGLEQNKALSSAVQASPTSPGGSPSS PSSGQRSASPSVPGPTKPKPKTKRFQLPLDKGNGKKHKVSHLRTSSSEAHIPDQETTSLTSGTGTPGAEAEQQDTASVEQSSQKECGQPA GQVAVLPEVQVTQNPANEQESAEPKTVEEEESNFSSPLMLWLQQEQKRKESITEKKPKKGLVFEISSDDGFQICAESIEDAWKSLTDKVQ EARSNARLKQLSFAGVNGLRMLGILHDAVVFLIEQLSGAKHCRNYKFRFHKPEEANEPPLNPHGSARAEVHLRKSAFDMFNFLASKHRQP PEYNPNDEEEEEVQLKSARRATSMDLPMPMRFRHLKKTSKEAVGVYRSPIHGRGLFCKRNIDAGEMVIEYAGNVIRSIQTDKREKYYDSK GIGCYMFRIDDSEVVDATMHGNAARFINHSCEPNCYSRVINIDGQKHIVIFAMRKIYRGEELTYDYKFPIEDASNKLPCNCGAKKCRKFL -------------------------------------------------------------- >2660_2660_34_AFF1-KMT2A_AFF1_chr4_88005317_ENST00000395146_KMT2A_chr11_118354896_ENST00000354520_length(amino acids)=2940AA_BP=371 METMAFTERVNSSGNSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKTAKGDELSSRIQNMLGNYEEVKEFLSTKSHTHRL DASENRLGKPKYPLIPDKGSSIPSSSFHTSVHHQSIHTPASGPLSVGNISHNPKMAQPRTEPMPSLHAKSCGPPDSQHLTQDRLGQEGFG SSHHKKGDRRADGDHCASVTDSAPERELSPLISLPSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNNSKGYCPAKSPKDLAVKVHDKETPQ DSLVAPAQPPSQTFPPPSLPSKSVAMQQKPTAYVRPMDGQDQAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYS NEVHCVEEILKEKPPPVNKQENAGTLNILSTLSNGNSSKQKIPADGVHRIRVDFKFVYCQVCCEPFHKFCLEENERPLEDQLENWCCRRC KFCHVCGRQHQATKQLLECNKCRNSYHPECLGPNYPTKPTKKKKVWICTKCVRCKSCGSTTPGKGWDAQWSHDFSLCHDCAKLFAKGNFC PLCDKCYDDDDYESKMMQCGKCDRWVHSKCENLSDEMYEILSNLPESVAYTCVNCTERHPAEWRLALEKELQISLKQVLTALLNSRTTSH LLRYRQAAKPPDLNPETEESIPSRSSPEGPDPPVLTEVSKQDDQQPLDLEGVKRKMDQGNYTSVLEFSDDIVKIIQAAINSDGGQPEIKK ANSMVKSFFIRQMERVFPWFSVKKSRFWEPNKVSSNSGMLPNAVLPPSLDHNYAQWQEREENSHTEQPPLMKKIIPAPKPKGPGEPDSPT PLHPPTPPILSTDRSREDSPELNPPPGIEDNRQCALCLTYGDDSANDAGRLLYIGQNEWTHVNCALWSAEVFEDDDGSLKNVHMAVIRGK QLRCEFCQKPGATVGCCLTSCTSNYHFMCSRAKNCVFLDDKKVYCQRHRDLIKGEVVPENGFEVFRRVFVDFEGISLRRKFLNGLEPENI HMMIGSMTIDCLGILNDLSDCEDKLFPIGYQCSRVYWSTTDARKRCVYTCKIVECRPPVVEPDINSTVEHDENRTIAHSPTSFTESSSKE SQNTAEIISPPSPDRPPHSQTSGSCYYHVISKVPRIRTPSYSPTQRSPGCRPLPSAGSPTPTTHEIVTVGDPLLSSGLRSIGSRRHSTSS LSPQRSKLRIMSPMRTGNTYSRNNVSSVSTTGTATDLESSAKVVDHVLGPLNSSTSLGQNTSTSSNLQRTVVTVGNKNSHLDGSSSSEMK QSSASDLVSKSSSLKGEKTKVLSSKSSEGSAHNVAYPGIPKLAPQVHNTTSRELNVSKIGSFAEPSSVSFSSKEALSFPHLHLRGQRNDR DQHTDSTQSANSSPDEDTEVKTLKLSGMSNRSSIINEHMGSSSRDRRQKGKKSCKETFKEKHSSKSFLEPGQVTTGEEGNLKPEFMDEVL TPEYMGQRPCNNVSSDKIGDKGLSMPGVPKAPPMQVEGSAKELQAPRKRTVKVTLTPLKMENESQSKNALKESSPASPLQIESTSPTEPI SASENPGDGPVAQPSPNNTSCQDSQSNNYQNLPVQDRNLMLPDGPKPQEDGSFKRRYPRRSARARSNMFFGLTPLYGVRSYGEEDIPFYS SSTGKKRGKRSAEGQVDGADDLSTSDEDDLYYYNFTRTVISSGGEERLASHNLFREEEQCDLPKISQLDGVDDGTESDTSVTATTRKSSQ IPKRNGKENGTENLKIDRPEDAGEKEHVTKSSVGHKNEPKMDNCHSVSRVKTQGQDSLEAQLSSLESSRRVHTSTPSDKNLLDTYNTELL KSDSDNNNSDDCGNILPSDIMDFVLKNTPSMQALGESPESSSSELLNLGEGLGLDSNREKDMGLFEVFSQQLPTTEPVDSSVSSSISAEE QFELPLELPSDLSVLTTRSPTVPSQNPSRLAVISDSGEKRVTITEKSVASSESDPALLSPGVDPTPEGHMTPDHFIQGHMDADHISSPPC GSVEQGHGNNQDLTRNSSTPGLQVPVSPTVPIQNQKYVPNSTDSPGPSQISNAAVQTTPPHLKPATEKLIVVNQNMQPLYVLQTLPNGVT QKIQLTSSVSSTPSVMETNTSVLGPMGGGLTLTTGLNPSLPTSQSLFPSASKGLLPMSHHQHLHSFPAATQSSFPPNISNPPSGLLIGVQ PPPDPQLLVSESSQRTDLSTTVATPSSGLKKRPISRLQTRKNKKLAPSSTPSNIAPSDVVSNMTLINFTPSQLPNHPSLLDLGSLNTSSH RTVPNIIKRSKSSIMYFEPAPLLPQSVGGTAATAAGTSTISQDTSHLTSGSVSGLASSSSVLNVVSMQTTTTPTSSASVPGHVTLTNPRL LGTPDIGSISNLLIKASQQSLGIQDQPVALPPSSGMFPQLGTSQTPSTAAITAASSICVLPSTQTTGITAASPSGEADEHYQLQHVNQLL ASKTGIHSSQRDLDSASGPQVSNFTQTVDAPNSMGLEQNKALSSAVQASPTSPGGSPSSPSSGQRSASPSVPGPTKPKPKTKRFQLPLDK GNGKKHKVSHLRTSSSEAHIPDQETTSLTSGTGTPGAEAEQQDTASVEQSSQKECGQPAGQVAVLPEVQVTQNPANEQESAEPKTVEEEE SNFSSPLMLWLQQEQKRKESITEKKPKKGLVFEISSDDGFQICAESIEDAWKSLTDKVQEARSNARLKQLSFAGVNGLRMLGILHDAVVF LIEQLSGAKHCRNYKFRFHKPEEANEPPLNPHGSARAEVHLRKSAFDMFNFLASKHRQPPEYNPNDEEEEEVQLKSARRATSMDLPMPMR FRHLKKTSKEAVGVYRSPIHGRGLFCKRNIDAGEMVIEYAGNVIRSIQTDKREKYYDSKGIGCYMFRIDDSEVVDATMHGNAARFINHSC -------------------------------------------------------------- >2660_2660_35_AFF1-KMT2A_AFF1_chr4_88005317_ENST00000395146_KMT2A_chr11_118354896_ENST00000389506_length(amino acids)=2978AA_BP=371 METMAFTERVNSSGNSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKTAKGDELSSRIQNMLGNYEEVKEFLSTKSHTHRL DASENRLGKPKYPLIPDKGSSIPSSSFHTSVHHQSIHTPASGPLSVGNISHNPKMAQPRTEPMPSLHAKSCGPPDSQHLTQDRLGQEGFG SSHHKKGDRRADGDHCASVTDSAPERELSPLISLPSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNNSKGYCPAKSPKDLAVKVHDKETPQ DSLVAPAQPPSQTFPPPSLPSKSVAMQQKPTAYVRPMDGQDQAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYS NEVHCVEEILKEKPPPVNKQENAGTLNILSTLSNGNSSKQKIPADGVHRIRVDFKEDCEAENVWEMGGLGILTSVPITPRVVCFLCASSG HVEFVYCQVCCEPFHKFCLEENERPLEDQLENWCCRRCKFCHVCGRQHQATKQLLECNKCRNSYHPECLGPNYPTKPTKKKKVWICTKCV RCKSCGSTTPGKGWDAQWSHDFSLCHDCAKLFAKGNFCPLCDKCYDDDDYESKMMQCGKCDRWVHSKCENLSDEMYEILSNLPESVAYTC VNCTERHPAEWRLALEKELQISLKQVLTALLNSRTTSHLLRYRQAAKPPDLNPETEESIPSRSSPEGPDPPVLTEVSKQDDQQPLDLEGV KRKMDQGNYTSVLEFSDDIVKIIQAAINSDGGQPEIKKANSMVKSFFIRQMERVFPWFSVKKSRFWEPNKVSSNSGMLPNAVLPPSLDHN YAQWQEREENSHTEQPPLMKKIIPAPKPKGPGEPDSPTPLHPPTPPILSTDRSREDSPELNPPPGIEDNRQCALCLTYGDDSANDAGRLL YIGQNEWTHVNCALWSAEVFEDDDGSLKNVHMAVIRGKQLRCEFCQKPGATVGCCLTSCTSNYHFMCSRAKNCVFLDDKKVYCQRHRDLI KGEVVPENGFEVFRRVFVDFEGISLRRKFLNGLEPENIHMMIGSMTIDCLGILNDLSDCEDKLFPIGYQCSRVYWSTTDARKRCVYTCKI VECRPPVVEPDINSTVEHDENRTIAHSPTSFTESSSKESQNTAEIISPPSPDRPPHSQTSGSCYYHVISKVPRIRTPSYSPTQRSPGCRP LPSAGSPTPTTHEIVTVGDPLLSSGLRSIGSRRHSTSSLSPQRSKLRIMSPMRTGNTYSRNNVSSVSTTGTATDLESSAKVVDHVLGPLN SSTSLGQNTSTSSNLQRTVVTVGNKNSHLDGSSSSEMKQSSASDLVSKSSSLKGEKTKVLSSKSSEGSAHNVAYPGIPKLAPQVHNTTSR ELNVSKIGSFAEPSSVSFSSKEALSFPHLHLRGQRNDRDQHTDSTQSANSSPDEDTEVKTLKLSGMSNRSSIINEHMGSSSRDRRQKGKK SCKETFKEKHSSKSFLEPGQVTTGEEGNLKPEFMDEVLTPEYMGQRPCNNVSSDKIGDKGLSMPGVPKAPPMQVEGSAKELQAPRKRTVK VTLTPLKMENESQSKNALKESSPASPLQIESTSPTEPISASENPGDGPVAQPSPNNTSCQDSQSNNYQNLPVQDRNLMLPDGPKPQEDGS FKRRYPRRSARARSNMFFGLTPLYGVRSYGEEDIPFYSSSTGKKRGKRSAEGQVDGADDLSTSDEDDLYYYNFTRTVISSGGEERLASHN LFREEEQCDLPKISQLDGVDDGTESDTSVTATTRKSSQIPKRNGKENGTENLKIDRPEDAGEKEHVTKSSVGHKNEPKMDNCHSVSRVKT QGQDSLEAQLSSLESSRRVHTSTPSDKNLLDTYNTELLKSDSDNNNSDDCGNILPSDIMDFVLKNTPSMQALGESPESSSSELLNLGEGL GLDSNREKDMGLFEVFSQQLPTTEPVDSSVSSSISAEEQFELPLELPSDLSVLTTRSPTVPSQNPSRLAVISDSGEKRVTITEKSVASSE SDPALLSPGVDPTPEGHMTPDHFIQGHMDADHISSPPCGSVEQGHGNNQDLTRNSSTPGLQVPVSPTVPIQNQKYVPNSTDSPGPSQISN AAVQTTPPHLKPATEKLIVVNQNMQPLYVLQTLPNGVTQKIQLTSSVSSTPSVMETNTSVLGPMGGGLTLTTGLNPSLPTSQSLFPSASK GLLPMSHHQHLHSFPAATQSSFPPNISNPPSGLLIGVQPPPDPQLLVSESSQRTDLSTTVATPSSGLKKRPISRLQTRKNKKLAPSSTPS NIAPSDVVSNMTLINFTPSQLPNHPSLLDLGSLNTSSHRTVPNIIKRSKSSIMYFEPAPLLPQSVGGTAATAAGTSTISQDTSHLTSGSV SGLASSSSVLNVVSMQTTTTPTSSASVPGHVTLTNPRLLGTPDIGSISNLLIKASQQSLGIQDQPVALPPSSGMFPQLGTSQTPSTAAIT AASSICVLPSTQTTGITAASPSGEADEHYQLQHVNQLLASKTGIHSSQRDLDSASGPQVSNFTQTVDAPNSMGLEQNKALSSAVQASPTS PGGSPSSPSSGQRSASPSVPGPTKPKPKTKRFQLPLDKGNGKKHKVSHLRTSSSEAHIPDQETTSLTSGTGTPGAEAEQQDTASVEQSSQ KECGQPAGQVAVLPEVQVTQNPANEQESAEPKTVEEEESNFSSPLMLWLQQEQKRKESITEKKPKKGLVFEISSDDGFQICAESIEDAWK SLTDKVQEARSNARLKQLSFAGVNGLRMLGILHDAVVFLIEQLSGAKHCRNYKFRFHKPEEANEPPLNPHGSARAEVHLRKSAFDMFNFL ASKHRQPPEYNPNDEEEEEVQLKSARRATSMDLPMPMRFRHLKKTSKEAVGVYRSPIHGRGLFCKRNIDAGEMVIEYAGNVIRSIQTDKR EKYYDSKGIGCYMFRIDDSEVVDATMHGNAARFINHSCEPNCYSRVINIDGQKHIVIFAMRKIYRGEELTYDYKFPIEDASNKLPCNCGA -------------------------------------------------------------- >2660_2660_36_AFF1-KMT2A_AFF1_chr4_88005317_ENST00000395146_KMT2A_chr11_118354896_ENST00000534358_length(amino acids)=2981AA_BP=371 METMAFTERVNSSGNSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKTAKGDELSSRIQNMLGNYEEVKEFLSTKSHTHRL DASENRLGKPKYPLIPDKGSSIPSSSFHTSVHHQSIHTPASGPLSVGNISHNPKMAQPRTEPMPSLHAKSCGPPDSQHLTQDRLGQEGFG SSHHKKGDRRADGDHCASVTDSAPERELSPLISLPSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNNSKGYCPAKSPKDLAVKVHDKETPQ DSLVAPAQPPSQTFPPPSLPSKSVAMQQKPTAYVRPMDGQDQAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYS NEVHCVEEILKEKPPPVNKQENAGTLNILSTLSNGNSSKQKIPADGVHRIRVDFKEDCEAENVWEMGGLGILTSVPITPRVVCFLCASSG HVEFVYCQVCCEPFHKFCLEENERPLEDQLENWCCRRCKFCHVCGRQHQATKQLLECNKCRNSYHPECLGPNYPTKPTKKKKVWICTKCV RCKSCGSTTPGKGWDAQWSHDFSLCHDCAKLFAKGNFCPLCDKCYDDDDYESKMMQCGKCDRWVHSKCENLSGTEDEMYEILSNLPESVA YTCVNCTERHPAEWRLALEKELQISLKQVLTALLNSRTTSHLLRYRQAAKPPDLNPETEESIPSRSSPEGPDPPVLTEVSKQDDQQPLDL EGVKRKMDQGNYTSVLEFSDDIVKIIQAAINSDGGQPEIKKANSMVKSFFIRQMERVFPWFSVKKSRFWEPNKVSSNSGMLPNAVLPPSL DHNYAQWQEREENSHTEQPPLMKKIIPAPKPKGPGEPDSPTPLHPPTPPILSTDRSREDSPELNPPPGIEDNRQCALCLTYGDDSANDAG RLLYIGQNEWTHVNCALWSAEVFEDDDGSLKNVHMAVIRGKQLRCEFCQKPGATVGCCLTSCTSNYHFMCSRAKNCVFLDDKKVYCQRHR DLIKGEVVPENGFEVFRRVFVDFEGISLRRKFLNGLEPENIHMMIGSMTIDCLGILNDLSDCEDKLFPIGYQCSRVYWSTTDARKRCVYT CKIVECRPPVVEPDINSTVEHDENRTIAHSPTSFTESSSKESQNTAEIISPPSPDRPPHSQTSGSCYYHVISKVPRIRTPSYSPTQRSPG CRPLPSAGSPTPTTHEIVTVGDPLLSSGLRSIGSRRHSTSSLSPQRSKLRIMSPMRTGNTYSRNNVSSVSTTGTATDLESSAKVVDHVLG PLNSSTSLGQNTSTSSNLQRTVVTVGNKNSHLDGSSSSEMKQSSASDLVSKSSSLKGEKTKVLSSKSSEGSAHNVAYPGIPKLAPQVHNT TSRELNVSKIGSFAEPSSVSFSSKEALSFPHLHLRGQRNDRDQHTDSTQSANSSPDEDTEVKTLKLSGMSNRSSIINEHMGSSSRDRRQK GKKSCKETFKEKHSSKSFLEPGQVTTGEEGNLKPEFMDEVLTPEYMGQRPCNNVSSDKIGDKGLSMPGVPKAPPMQVEGSAKELQAPRKR TVKVTLTPLKMENESQSKNALKESSPASPLQIESTSPTEPISASENPGDGPVAQPSPNNTSCQDSQSNNYQNLPVQDRNLMLPDGPKPQE DGSFKRRYPRRSARARSNMFFGLTPLYGVRSYGEEDIPFYSSSTGKKRGKRSAEGQVDGADDLSTSDEDDLYYYNFTRTVISSGGEERLA SHNLFREEEQCDLPKISQLDGVDDGTESDTSVTATTRKSSQIPKRNGKENGTENLKIDRPEDAGEKEHVTKSSVGHKNEPKMDNCHSVSR VKTQGQDSLEAQLSSLESSRRVHTSTPSDKNLLDTYNTELLKSDSDNNNSDDCGNILPSDIMDFVLKNTPSMQALGESPESSSSELLNLG EGLGLDSNREKDMGLFEVFSQQLPTTEPVDSSVSSSISAEEQFELPLELPSDLSVLTTRSPTVPSQNPSRLAVISDSGEKRVTITEKSVA SSESDPALLSPGVDPTPEGHMTPDHFIQGHMDADHISSPPCGSVEQGHGNNQDLTRNSSTPGLQVPVSPTVPIQNQKYVPNSTDSPGPSQ ISNAAVQTTPPHLKPATEKLIVVNQNMQPLYVLQTLPNGVTQKIQLTSSVSSTPSVMETNTSVLGPMGGGLTLTTGLNPSLPTSQSLFPS ASKGLLPMSHHQHLHSFPAATQSSFPPNISNPPSGLLIGVQPPPDPQLLVSESSQRTDLSTTVATPSSGLKKRPISRLQTRKNKKLAPSS TPSNIAPSDVVSNMTLINFTPSQLPNHPSLLDLGSLNTSSHRTVPNIIKRSKSSIMYFEPAPLLPQSVGGTAATAAGTSTISQDTSHLTS GSVSGLASSSSVLNVVSMQTTTTPTSSASVPGHVTLTNPRLLGTPDIGSISNLLIKASQQSLGIQDQPVALPPSSGMFPQLGTSQTPSTA AITAASSICVLPSTQTTGITAASPSGEADEHYQLQHVNQLLASKTGIHSSQRDLDSASGPQVSNFTQTVDAPNSMGLEQNKALSSAVQAS PTSPGGSPSSPSSGQRSASPSVPGPTKPKPKTKRFQLPLDKGNGKKHKVSHLRTSSSEAHIPDQETTSLTSGTGTPGAEAEQQDTASVEQ SSQKECGQPAGQVAVLPEVQVTQNPANEQESAEPKTVEEEESNFSSPLMLWLQQEQKRKESITEKKPKKGLVFEISSDDGFQICAESIED AWKSLTDKVQEARSNARLKQLSFAGVNGLRMLGILHDAVVFLIEQLSGAKHCRNYKFRFHKPEEANEPPLNPHGSARAEVHLRKSAFDMF NFLASKHRQPPEYNPNDEEEEEVQLKSARRATSMDLPMPMRFRHLKKTSKEAVGVYRSPIHGRGLFCKRNIDAGEMVIEYAGNVIRSIQT DKREKYYDSKGIGCYMFRIDDSEVVDATMHGNAARFINHSCEPNCYSRVINIDGQKHIVIFAMRKIYRGEELTYDYKFPIEDASNKLPCN -------------------------------------------------------------- |
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Fusion Protein Functional Features |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr4:118353210/chr11:88005270) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| AFF1 | KMT2A |
| FUNCTION: Histone methyltransferase that plays an essential role in early development and hematopoiesis (PubMed:15960975, PubMed:12453419, PubMed:15960975, PubMed:19556245, PubMed:19187761, PubMed:20677832, PubMed:21220120, PubMed:26886794). Catalytic subunit of the MLL1/MLL complex, a multiprotein complex that mediates both methylation of 'Lys-4' of histone H3 (H3K4me) complex and acetylation of 'Lys-16' of histone H4 (H4K16ac) (PubMed:15960975, PubMed:12453419, PubMed:15960975, PubMed:19556245, PubMed:24235145, PubMed:19187761, PubMed:20677832, PubMed:21220120, PubMed:26886794). Catalyzes methyl group transfer from S-adenosyl-L-methionine to the epsilon-amino group of 'Lys-4' of histone H3 (H3K4) via a non-processive mechanism. Part of chromatin remodeling machinery predominantly forms H3K4me1 and H3K4me2 methylation marks at active chromatin sites where transcription and DNA repair take place (PubMed:25561738, PubMed:15960975, PubMed:12453419, PubMed:15960975, PubMed:19556245, PubMed:19187761, PubMed:20677832, PubMed:21220120, PubMed:26886794). Has weak methyltransferase activity by itself, and requires other component of the MLL1/MLL complex to obtain full methyltransferase activity (PubMed:19187761, PubMed:26886794). Has no activity toward histone H3 phosphorylated on 'Thr-3', less activity toward H3 dimethylated on 'Arg-8' or 'Lys-9', while it has higher activity toward H3 acetylated on 'Lys-9' (PubMed:19187761). Binds to unmethylated CpG elements in the promoter of target genes and helps maintain them in the nonmethylated state (PubMed:20010842). Required for transcriptional activation of HOXA9 (PubMed:12453419, PubMed:20677832, PubMed:20010842). Promotes PPP1R15A-induced apoptosis (PubMed:10490642). Plays a critical role in the control of circadian gene expression and is essential for the transcriptional activation mediated by the CLOCK-ARNTL/BMAL1 heterodimer (By similarity). Establishes a permissive chromatin state for circadian transcription by mediating a rhythmic methylation of 'Lys-4' of histone H3 (H3K4me) and this histone modification directs the circadian acetylation at H3K9 and H3K14 allowing the recruitment of CLOCK-ARNTL/BMAL1 to chromatin (By similarity). Also has auto-methylation activity on Cys-3882 in absence of histone H3 substrate (PubMed:24235145). {ECO:0000250|UniProtKB:P55200, ECO:0000269|PubMed:10490642, ECO:0000269|PubMed:12453419, ECO:0000269|PubMed:15960975, ECO:0000269|PubMed:19187761, ECO:0000269|PubMed:19556245, ECO:0000269|PubMed:20010842, ECO:0000269|PubMed:21220120, ECO:0000269|PubMed:24235145, ECO:0000269|PubMed:26886794, ECO:0000305|PubMed:20677832}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - Retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | AFF1 | chr4:87967438 | chr11:118354897 | ENST00000307808 | 2 | 20 | 12_37 | 46.0 | 1211.0 | Compositional bias | Basic and acidic residues | |
| Hgene | AFF1 | chr4:87967438 | chr11:118354897 | ENST00000395146 | 3 | 21 | 12_37 | 53.0 | 1219.0 | Compositional bias | Basic and acidic residues | |
| Hgene | AFF1 | chr4:87967438 | chr11:118359328 | ENST00000307808 | 2 | 20 | 12_37 | 46.0 | 1211.0 | Compositional bias | Basic and acidic residues | |
| Hgene | AFF1 | chr4:87967438 | chr11:118359328 | ENST00000395146 | 3 | 21 | 12_37 | 53.0 | 1219.0 | Compositional bias | Basic and acidic residues | |
| Hgene | AFF1 | chr4:87968746 | chr11:118354897 | ENST00000307808 | 3 | 20 | 12_37 | 346.0 | 1211.0 | Compositional bias | Basic and acidic residues | |
| Hgene | AFF1 | chr4:87968746 | chr11:118354897 | ENST00000307808 | 3 | 20 | 168_191 | 346.0 | 1211.0 | Compositional bias | Basic and acidic residues | |
| Hgene | AFF1 | chr4:87968746 | chr11:118354897 | ENST00000307808 | 3 | 20 | 213_241 | 346.0 | 1211.0 | Compositional bias | Polar residues | |
| Hgene | AFF1 | chr4:87968746 | chr11:118354897 | ENST00000307808 | 3 | 20 | 99_135 | 346.0 | 1211.0 | Compositional bias | Polar residues | |
| Hgene | AFF1 | chr4:87968746 | chr11:118354897 | ENST00000395146 | 4 | 21 | 12_37 | 353.0 | 1219.0 | Compositional bias | Basic and acidic residues | |
| Hgene | AFF1 | chr4:87968746 | chr11:118354897 | ENST00000395146 | 4 | 21 | 168_191 | 353.0 | 1219.0 | Compositional bias | Basic and acidic residues | |
| Hgene | AFF1 | chr4:87968746 | chr11:118354897 | ENST00000395146 | 4 | 21 | 213_241 | 353.0 | 1219.0 | Compositional bias | Polar residues | |
| Hgene | AFF1 | chr4:87968746 | chr11:118354897 | ENST00000395146 | 4 | 21 | 99_135 | 353.0 | 1219.0 | Compositional bias | Polar residues | |
| Hgene | AFF1 | chr4:87967438 | chr11:118354897 | ENST00000307808 | 2 | 20 | 1_45 | 46.0 | 1211.0 | Region | Disordered | |
| Hgene | AFF1 | chr4:87967438 | chr11:118354897 | ENST00000395146 | 3 | 21 | 1_45 | 53.0 | 1219.0 | Region | Disordered | |
| Hgene | AFF1 | chr4:87967438 | chr11:118359328 | ENST00000307808 | 2 | 20 | 1_45 | 46.0 | 1211.0 | Region | Disordered | |
| Hgene | AFF1 | chr4:87967438 | chr11:118359328 | ENST00000395146 | 3 | 21 | 1_45 | 53.0 | 1219.0 | Region | Disordered | |
| Hgene | AFF1 | chr4:87968746 | chr11:118354897 | ENST00000307808 | 3 | 20 | 1_45 | 346.0 | 1211.0 | Region | Disordered | |
| Hgene | AFF1 | chr4:87968746 | chr11:118354897 | ENST00000307808 | 3 | 20 | 73_314 | 346.0 | 1211.0 | Region | Disordered | |
| Hgene | AFF1 | chr4:87968746 | chr11:118354897 | ENST00000395146 | 4 | 21 | 1_45 | 353.0 | 1219.0 | Region | Disordered | |
| Hgene | AFF1 | chr4:87968746 | chr11:118354897 | ENST00000395146 | 4 | 21 | 73_314 | 353.0 | 1219.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000354520 | 7 | 35 | 1822_1847 | 1362.0 | 3932.0 | Compositional bias | Pro residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000354520 | 7 | 35 | 2096_2118 | 1362.0 | 3932.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000354520 | 7 | 35 | 2146_2174 | 1362.0 | 3932.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000354520 | 7 | 35 | 2189_2232 | 1362.0 | 3932.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000354520 | 7 | 35 | 2275_2320 | 1362.0 | 3932.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000354520 | 7 | 35 | 2402_2418 | 1362.0 | 3932.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000354520 | 7 | 35 | 2419_2445 | 1362.0 | 3932.0 | Compositional bias | Basic and acidic residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000354520 | 7 | 35 | 2526_2594 | 1362.0 | 3932.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000354520 | 7 | 35 | 2721_2746 | 1362.0 | 3932.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000354520 | 7 | 35 | 2747_2784 | 1362.0 | 3932.0 | Compositional bias | Basic and acidic residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000354520 | 7 | 35 | 2785_2821 | 1362.0 | 3932.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000354520 | 7 | 35 | 3011_3064 | 1362.0 | 3932.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000354520 | 7 | 35 | 3166_3183 | 1362.0 | 3932.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000354520 | 7 | 35 | 3195_3222 | 1362.0 | 3932.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000354520 | 7 | 35 | 3230_3244 | 1362.0 | 3932.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000354520 | 7 | 35 | 3464_3530 | 1362.0 | 3932.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000354520 | 7 | 35 | 3563_3606 | 1362.0 | 3932.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000389506 | 7 | 36 | 1822_1847 | 1362.0 | 3970.0 | Compositional bias | Pro residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000389506 | 7 | 36 | 2096_2118 | 1362.0 | 3970.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000389506 | 7 | 36 | 2146_2174 | 1362.0 | 3970.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000389506 | 7 | 36 | 2189_2232 | 1362.0 | 3970.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000389506 | 7 | 36 | 2275_2320 | 1362.0 | 3970.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000389506 | 7 | 36 | 2402_2418 | 1362.0 | 3970.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000389506 | 7 | 36 | 2419_2445 | 1362.0 | 3970.0 | Compositional bias | Basic and acidic residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000389506 | 7 | 36 | 2526_2594 | 1362.0 | 3970.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000389506 | 7 | 36 | 2721_2746 | 1362.0 | 3970.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000389506 | 7 | 36 | 2747_2784 | 1362.0 | 3970.0 | Compositional bias | Basic and acidic residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000389506 | 7 | 36 | 2785_2821 | 1362.0 | 3970.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000389506 | 7 | 36 | 3011_3064 | 1362.0 | 3970.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000389506 | 7 | 36 | 3166_3183 | 1362.0 | 3970.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000389506 | 7 | 36 | 3195_3222 | 1362.0 | 3970.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000389506 | 7 | 36 | 3230_3244 | 1362.0 | 3970.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000389506 | 7 | 36 | 3464_3530 | 1362.0 | 3970.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000389506 | 7 | 36 | 3563_3606 | 1362.0 | 3970.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000534358 | 7 | 36 | 1822_1847 | 1362.0 | 3973.0 | Compositional bias | Pro residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000534358 | 7 | 36 | 2096_2118 | 1362.0 | 3973.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000534358 | 7 | 36 | 2146_2174 | 1362.0 | 3973.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000534358 | 7 | 36 | 2189_2232 | 1362.0 | 3973.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000534358 | 7 | 36 | 2275_2320 | 1362.0 | 3973.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000534358 | 7 | 36 | 2402_2418 | 1362.0 | 3973.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000534358 | 7 | 36 | 2419_2445 | 1362.0 | 3973.0 | Compositional bias | Basic and acidic residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000534358 | 7 | 36 | 2526_2594 | 1362.0 | 3973.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000534358 | 7 | 36 | 2721_2746 | 1362.0 | 3973.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000534358 | 7 | 36 | 2747_2784 | 1362.0 | 3973.0 | Compositional bias | Basic and acidic residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000534358 | 7 | 36 | 2785_2821 | 1362.0 | 3973.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000534358 | 7 | 36 | 3011_3064 | 1362.0 | 3973.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000534358 | 7 | 36 | 3166_3183 | 1362.0 | 3973.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000534358 | 7 | 36 | 3195_3222 | 1362.0 | 3973.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000534358 | 7 | 36 | 3230_3244 | 1362.0 | 3973.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000534358 | 7 | 36 | 3464_3530 | 1362.0 | 3973.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000534358 | 7 | 36 | 3563_3606 | 1362.0 | 3973.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000354520 | 8 | 35 | 1822_1847 | 1406.0 | 3932.0 | Compositional bias | Pro residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000354520 | 8 | 35 | 2096_2118 | 1406.0 | 3932.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000354520 | 8 | 35 | 2146_2174 | 1406.0 | 3932.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000354520 | 8 | 35 | 2189_2232 | 1406.0 | 3932.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000354520 | 8 | 35 | 2275_2320 | 1406.0 | 3932.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000354520 | 8 | 35 | 2402_2418 | 1406.0 | 3932.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000354520 | 8 | 35 | 2419_2445 | 1406.0 | 3932.0 | Compositional bias | Basic and acidic residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000354520 | 8 | 35 | 2526_2594 | 1406.0 | 3932.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000354520 | 8 | 35 | 2721_2746 | 1406.0 | 3932.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000354520 | 8 | 35 | 2747_2784 | 1406.0 | 3932.0 | Compositional bias | Basic and acidic residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000354520 | 8 | 35 | 2785_2821 | 1406.0 | 3932.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000354520 | 8 | 35 | 3011_3064 | 1406.0 | 3932.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000354520 | 8 | 35 | 3166_3183 | 1406.0 | 3932.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000354520 | 8 | 35 | 3195_3222 | 1406.0 | 3932.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000354520 | 8 | 35 | 3230_3244 | 1406.0 | 3932.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000354520 | 8 | 35 | 3464_3530 | 1406.0 | 3932.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000354520 | 8 | 35 | 3563_3606 | 1406.0 | 3932.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000389506 | 9 | 36 | 1822_1847 | 1444.0 | 3970.0 | Compositional bias | Pro residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000389506 | 9 | 36 | 2096_2118 | 1444.0 | 3970.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000389506 | 9 | 36 | 2146_2174 | 1444.0 | 3970.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000389506 | 9 | 36 | 2189_2232 | 1444.0 | 3970.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000389506 | 9 | 36 | 2275_2320 | 1444.0 | 3970.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000389506 | 9 | 36 | 2402_2418 | 1444.0 | 3970.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000389506 | 9 | 36 | 2419_2445 | 1444.0 | 3970.0 | Compositional bias | Basic and acidic residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000389506 | 9 | 36 | 2526_2594 | 1444.0 | 3970.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000389506 | 9 | 36 | 2721_2746 | 1444.0 | 3970.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000389506 | 9 | 36 | 2747_2784 | 1444.0 | 3970.0 | Compositional bias | Basic and acidic residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000389506 | 9 | 36 | 2785_2821 | 1444.0 | 3970.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000389506 | 9 | 36 | 3011_3064 | 1444.0 | 3970.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000389506 | 9 | 36 | 3166_3183 | 1444.0 | 3970.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000389506 | 9 | 36 | 3195_3222 | 1444.0 | 3970.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000389506 | 9 | 36 | 3230_3244 | 1444.0 | 3970.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000389506 | 9 | 36 | 3464_3530 | 1444.0 | 3970.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000389506 | 9 | 36 | 3563_3606 | 1444.0 | 3970.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000534358 | 9 | 36 | 1822_1847 | 1444.0 | 3973.0 | Compositional bias | Pro residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000534358 | 9 | 36 | 2096_2118 | 1444.0 | 3973.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000534358 | 9 | 36 | 2146_2174 | 1444.0 | 3973.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000534358 | 9 | 36 | 2189_2232 | 1444.0 | 3973.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000534358 | 9 | 36 | 2275_2320 | 1444.0 | 3973.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000534358 | 9 | 36 | 2402_2418 | 1444.0 | 3973.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000534358 | 9 | 36 | 2419_2445 | 1444.0 | 3973.0 | Compositional bias | Basic and acidic residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000534358 | 9 | 36 | 2526_2594 | 1444.0 | 3973.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000534358 | 9 | 36 | 2721_2746 | 1444.0 | 3973.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000534358 | 9 | 36 | 2747_2784 | 1444.0 | 3973.0 | Compositional bias | Basic and acidic residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000534358 | 9 | 36 | 2785_2821 | 1444.0 | 3973.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000534358 | 9 | 36 | 3011_3064 | 1444.0 | 3973.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000534358 | 9 | 36 | 3166_3183 | 1444.0 | 3973.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000534358 | 9 | 36 | 3195_3222 | 1444.0 | 3973.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000534358 | 9 | 36 | 3230_3244 | 1444.0 | 3973.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000534358 | 9 | 36 | 3464_3530 | 1444.0 | 3973.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000534358 | 9 | 36 | 3563_3606 | 1444.0 | 3973.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000354520 | 7 | 35 | 1822_1847 | 1362.0 | 3932.0 | Compositional bias | Pro residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000354520 | 7 | 35 | 2096_2118 | 1362.0 | 3932.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000354520 | 7 | 35 | 2146_2174 | 1362.0 | 3932.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000354520 | 7 | 35 | 2189_2232 | 1362.0 | 3932.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000354520 | 7 | 35 | 2275_2320 | 1362.0 | 3932.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000354520 | 7 | 35 | 2402_2418 | 1362.0 | 3932.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000354520 | 7 | 35 | 2419_2445 | 1362.0 | 3932.0 | Compositional bias | Basic and acidic residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000354520 | 7 | 35 | 2526_2594 | 1362.0 | 3932.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000354520 | 7 | 35 | 2721_2746 | 1362.0 | 3932.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000354520 | 7 | 35 | 2747_2784 | 1362.0 | 3932.0 | Compositional bias | Basic and acidic residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000354520 | 7 | 35 | 2785_2821 | 1362.0 | 3932.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000354520 | 7 | 35 | 3011_3064 | 1362.0 | 3932.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000354520 | 7 | 35 | 3166_3183 | 1362.0 | 3932.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000354520 | 7 | 35 | 3195_3222 | 1362.0 | 3932.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000354520 | 7 | 35 | 3230_3244 | 1362.0 | 3932.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000354520 | 7 | 35 | 3464_3530 | 1362.0 | 3932.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000354520 | 7 | 35 | 3563_3606 | 1362.0 | 3932.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000389506 | 7 | 36 | 1822_1847 | 1362.0 | 3970.0 | Compositional bias | Pro residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000389506 | 7 | 36 | 2096_2118 | 1362.0 | 3970.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000389506 | 7 | 36 | 2146_2174 | 1362.0 | 3970.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000389506 | 7 | 36 | 2189_2232 | 1362.0 | 3970.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000389506 | 7 | 36 | 2275_2320 | 1362.0 | 3970.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000389506 | 7 | 36 | 2402_2418 | 1362.0 | 3970.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000389506 | 7 | 36 | 2419_2445 | 1362.0 | 3970.0 | Compositional bias | Basic and acidic residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000389506 | 7 | 36 | 2526_2594 | 1362.0 | 3970.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000389506 | 7 | 36 | 2721_2746 | 1362.0 | 3970.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000389506 | 7 | 36 | 2747_2784 | 1362.0 | 3970.0 | Compositional bias | Basic and acidic residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000389506 | 7 | 36 | 2785_2821 | 1362.0 | 3970.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000389506 | 7 | 36 | 3011_3064 | 1362.0 | 3970.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000389506 | 7 | 36 | 3166_3183 | 1362.0 | 3970.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000389506 | 7 | 36 | 3195_3222 | 1362.0 | 3970.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000389506 | 7 | 36 | 3230_3244 | 1362.0 | 3970.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000389506 | 7 | 36 | 3464_3530 | 1362.0 | 3970.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000389506 | 7 | 36 | 3563_3606 | 1362.0 | 3970.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000534358 | 7 | 36 | 1822_1847 | 1362.0 | 3973.0 | Compositional bias | Pro residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000534358 | 7 | 36 | 2096_2118 | 1362.0 | 3973.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000534358 | 7 | 36 | 2146_2174 | 1362.0 | 3973.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000534358 | 7 | 36 | 2189_2232 | 1362.0 | 3973.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000534358 | 7 | 36 | 2275_2320 | 1362.0 | 3973.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000534358 | 7 | 36 | 2402_2418 | 1362.0 | 3973.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000534358 | 7 | 36 | 2419_2445 | 1362.0 | 3973.0 | Compositional bias | Basic and acidic residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000534358 | 7 | 36 | 2526_2594 | 1362.0 | 3973.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000534358 | 7 | 36 | 2721_2746 | 1362.0 | 3973.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000534358 | 7 | 36 | 2747_2784 | 1362.0 | 3973.0 | Compositional bias | Basic and acidic residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000534358 | 7 | 36 | 2785_2821 | 1362.0 | 3973.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000534358 | 7 | 36 | 3011_3064 | 1362.0 | 3973.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000534358 | 7 | 36 | 3166_3183 | 1362.0 | 3973.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000534358 | 7 | 36 | 3195_3222 | 1362.0 | 3973.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000534358 | 7 | 36 | 3230_3244 | 1362.0 | 3973.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000534358 | 7 | 36 | 3464_3530 | 1362.0 | 3973.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000534358 | 7 | 36 | 3563_3606 | 1362.0 | 3973.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000354520 | 7 | 35 | 1703_1748 | 1362.0 | 3932.0 | Domain | Bromo%3B divergent | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000354520 | 7 | 35 | 2018_2074 | 1362.0 | 3932.0 | Domain | FYR N-terminal | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000354520 | 7 | 35 | 3666_3747 | 1362.0 | 3932.0 | Domain | FYR C-terminal | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000354520 | 7 | 35 | 3829_3945 | 1362.0 | 3932.0 | Domain | SET | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000354520 | 7 | 35 | 3953_3969 | 1362.0 | 3932.0 | Domain | Post-SET | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000389506 | 7 | 36 | 1703_1748 | 1362.0 | 3970.0 | Domain | Bromo%3B divergent | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000389506 | 7 | 36 | 2018_2074 | 1362.0 | 3970.0 | Domain | FYR N-terminal | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000389506 | 7 | 36 | 3666_3747 | 1362.0 | 3970.0 | Domain | FYR C-terminal | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000389506 | 7 | 36 | 3829_3945 | 1362.0 | 3970.0 | Domain | SET | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000389506 | 7 | 36 | 3953_3969 | 1362.0 | 3970.0 | Domain | Post-SET | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000534358 | 7 | 36 | 1703_1748 | 1362.0 | 3973.0 | Domain | Bromo%3B divergent | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000534358 | 7 | 36 | 2018_2074 | 1362.0 | 3973.0 | Domain | FYR N-terminal | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000534358 | 7 | 36 | 3666_3747 | 1362.0 | 3973.0 | Domain | FYR C-terminal | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000534358 | 7 | 36 | 3829_3945 | 1362.0 | 3973.0 | Domain | SET | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000534358 | 7 | 36 | 3953_3969 | 1362.0 | 3973.0 | Domain | Post-SET | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000354520 | 8 | 35 | 1703_1748 | 1406.0 | 3932.0 | Domain | Bromo%3B divergent | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000354520 | 8 | 35 | 2018_2074 | 1406.0 | 3932.0 | Domain | FYR N-terminal | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000354520 | 8 | 35 | 3666_3747 | 1406.0 | 3932.0 | Domain | FYR C-terminal | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000354520 | 8 | 35 | 3829_3945 | 1406.0 | 3932.0 | Domain | SET | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000354520 | 8 | 35 | 3953_3969 | 1406.0 | 3932.0 | Domain | Post-SET | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000389506 | 9 | 36 | 1703_1748 | 1444.0 | 3970.0 | Domain | Bromo%3B divergent | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000389506 | 9 | 36 | 2018_2074 | 1444.0 | 3970.0 | Domain | FYR N-terminal | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000389506 | 9 | 36 | 3666_3747 | 1444.0 | 3970.0 | Domain | FYR C-terminal | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000389506 | 9 | 36 | 3829_3945 | 1444.0 | 3970.0 | Domain | SET | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000389506 | 9 | 36 | 3953_3969 | 1444.0 | 3970.0 | Domain | Post-SET | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000534358 | 9 | 36 | 1703_1748 | 1444.0 | 3973.0 | Domain | Bromo%3B divergent | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000534358 | 9 | 36 | 2018_2074 | 1444.0 | 3973.0 | Domain | FYR N-terminal | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000534358 | 9 | 36 | 3666_3747 | 1444.0 | 3973.0 | Domain | FYR C-terminal | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000534358 | 9 | 36 | 3829_3945 | 1444.0 | 3973.0 | Domain | SET | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000534358 | 9 | 36 | 3953_3969 | 1444.0 | 3973.0 | Domain | Post-SET | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000354520 | 7 | 35 | 1703_1748 | 1362.0 | 3932.0 | Domain | Bromo%3B divergent | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000354520 | 7 | 35 | 2018_2074 | 1362.0 | 3932.0 | Domain | FYR N-terminal | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000354520 | 7 | 35 | 3666_3747 | 1362.0 | 3932.0 | Domain | FYR C-terminal | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000354520 | 7 | 35 | 3829_3945 | 1362.0 | 3932.0 | Domain | SET | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000354520 | 7 | 35 | 3953_3969 | 1362.0 | 3932.0 | Domain | Post-SET | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000389506 | 7 | 36 | 1703_1748 | 1362.0 | 3970.0 | Domain | Bromo%3B divergent | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000389506 | 7 | 36 | 2018_2074 | 1362.0 | 3970.0 | Domain | FYR N-terminal | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000389506 | 7 | 36 | 3666_3747 | 1362.0 | 3970.0 | Domain | FYR C-terminal | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000389506 | 7 | 36 | 3829_3945 | 1362.0 | 3970.0 | Domain | SET | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000389506 | 7 | 36 | 3953_3969 | 1362.0 | 3970.0 | Domain | Post-SET | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000534358 | 7 | 36 | 1703_1748 | 1362.0 | 3973.0 | Domain | Bromo%3B divergent | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000534358 | 7 | 36 | 2018_2074 | 1362.0 | 3973.0 | Domain | FYR N-terminal | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000534358 | 7 | 36 | 3666_3747 | 1362.0 | 3973.0 | Domain | FYR C-terminal | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000534358 | 7 | 36 | 3829_3945 | 1362.0 | 3973.0 | Domain | SET | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000534358 | 7 | 36 | 3953_3969 | 1362.0 | 3973.0 | Domain | Post-SET | |
| Tgene | KMT2A | chr4:87968747 | chr11:118354896 | ENST00000354520 | 7 | 35 | 1703_1748 | 1362.0 | 3932.0 | Domain | Bromo%3B divergent | |
| Tgene | KMT2A | chr4:87968747 | chr11:118354896 | ENST00000354520 | 7 | 35 | 2018_2074 | 1362.0 | 3932.0 | Domain | FYR N-terminal | |
| Tgene | KMT2A | chr4:87968747 | chr11:118354896 | ENST00000354520 | 7 | 35 | 3666_3747 | 1362.0 | 3932.0 | Domain | FYR C-terminal | |
| Tgene | KMT2A | chr4:87968747 | chr11:118354896 | ENST00000354520 | 7 | 35 | 3829_3945 | 1362.0 | 3932.0 | Domain | SET | |
| Tgene | KMT2A | chr4:87968747 | chr11:118354896 | ENST00000354520 | 7 | 35 | 3953_3969 | 1362.0 | 3932.0 | Domain | Post-SET | |
| Tgene | KMT2A | chr4:87968747 | chr11:118354896 | ENST00000389506 | 7 | 36 | 1703_1748 | 1362.0 | 3970.0 | Domain | Bromo%3B divergent | |
| Tgene | KMT2A | chr4:87968747 | chr11:118354896 | ENST00000389506 | 7 | 36 | 2018_2074 | 1362.0 | 3970.0 | Domain | FYR N-terminal | |
| Tgene | KMT2A | chr4:87968747 | chr11:118354896 | ENST00000389506 | 7 | 36 | 3666_3747 | 1362.0 | 3970.0 | Domain | FYR C-terminal | |
| Tgene | KMT2A | chr4:87968747 | chr11:118354896 | ENST00000389506 | 7 | 36 | 3829_3945 | 1362.0 | 3970.0 | Domain | SET | |
| Tgene | KMT2A | chr4:87968747 | chr11:118354896 | ENST00000389506 | 7 | 36 | 3953_3969 | 1362.0 | 3970.0 | Domain | Post-SET | |
| Tgene | KMT2A | chr4:87968747 | chr11:118354896 | ENST00000534358 | 7 | 36 | 1703_1748 | 1362.0 | 3973.0 | Domain | Bromo%3B divergent | |
| Tgene | KMT2A | chr4:87968747 | chr11:118354896 | ENST00000534358 | 7 | 36 | 2018_2074 | 1362.0 | 3973.0 | Domain | FYR N-terminal | |
| Tgene | KMT2A | chr4:87968747 | chr11:118354896 | ENST00000534358 | 7 | 36 | 3666_3747 | 1362.0 | 3973.0 | Domain | FYR C-terminal | |
| Tgene | KMT2A | chr4:87968747 | chr11:118354896 | ENST00000534358 | 7 | 36 | 3829_3945 | 1362.0 | 3973.0 | Domain | SET | |
| Tgene | KMT2A | chr4:87968747 | chr11:118354896 | ENST00000534358 | 7 | 36 | 3953_3969 | 1362.0 | 3973.0 | Domain | Post-SET | |
| Tgene | KMT2A | chr4:87968752 | chr11:118359327 | ENST00000354520 | 8 | 35 | 1703_1748 | 1406.0 | 3932.0 | Domain | Bromo%3B divergent | |
| Tgene | KMT2A | chr4:87968752 | chr11:118359327 | ENST00000354520 | 8 | 35 | 2018_2074 | 1406.0 | 3932.0 | Domain | FYR N-terminal | |
| Tgene | KMT2A | chr4:87968752 | chr11:118359327 | ENST00000354520 | 8 | 35 | 3666_3747 | 1406.0 | 3932.0 | Domain | FYR C-terminal | |
| Tgene | KMT2A | chr4:87968752 | chr11:118359327 | ENST00000354520 | 8 | 35 | 3829_3945 | 1406.0 | 3932.0 | Domain | SET | |
| Tgene | KMT2A | chr4:87968752 | chr11:118359327 | ENST00000354520 | 8 | 35 | 3953_3969 | 1406.0 | 3932.0 | Domain | Post-SET | |
| Tgene | KMT2A | chr4:87968752 | chr11:118359327 | ENST00000389506 | 9 | 36 | 1703_1748 | 1444.0 | 3970.0 | Domain | Bromo%3B divergent | |
| Tgene | KMT2A | chr4:87968752 | chr11:118359327 | ENST00000389506 | 9 | 36 | 2018_2074 | 1444.0 | 3970.0 | Domain | FYR N-terminal | |
| Tgene | KMT2A | chr4:87968752 | chr11:118359327 | ENST00000389506 | 9 | 36 | 3666_3747 | 1444.0 | 3970.0 | Domain | FYR C-terminal | |
| Tgene | KMT2A | chr4:87968752 | chr11:118359327 | ENST00000389506 | 9 | 36 | 3829_3945 | 1444.0 | 3970.0 | Domain | SET | |
| Tgene | KMT2A | chr4:87968752 | chr11:118359327 | ENST00000389506 | 9 | 36 | 3953_3969 | 1444.0 | 3970.0 | Domain | Post-SET | |
| Tgene | KMT2A | chr4:87968752 | chr11:118359327 | ENST00000534358 | 9 | 36 | 1703_1748 | 1444.0 | 3973.0 | Domain | Bromo%3B divergent | |
| Tgene | KMT2A | chr4:87968752 | chr11:118359327 | ENST00000534358 | 9 | 36 | 2018_2074 | 1444.0 | 3973.0 | Domain | FYR N-terminal | |
| Tgene | KMT2A | chr4:87968752 | chr11:118359327 | ENST00000534358 | 9 | 36 | 3666_3747 | 1444.0 | 3973.0 | Domain | FYR C-terminal | |
| Tgene | KMT2A | chr4:87968752 | chr11:118359327 | ENST00000534358 | 9 | 36 | 3829_3945 | 1444.0 | 3973.0 | Domain | SET | |
| Tgene | KMT2A | chr4:87968752 | chr11:118359327 | ENST00000534358 | 9 | 36 | 3953_3969 | 1444.0 | 3973.0 | Domain | Post-SET | |
| Tgene | KMT2A | chr4:88005317 | chr11:118354896 | ENST00000354520 | 7 | 35 | 1703_1748 | 1362.0 | 3932.0 | Domain | Bromo%3B divergent | |
| Tgene | KMT2A | chr4:88005317 | chr11:118354896 | ENST00000354520 | 7 | 35 | 2018_2074 | 1362.0 | 3932.0 | Domain | FYR N-terminal | |
| Tgene | KMT2A | chr4:88005317 | chr11:118354896 | ENST00000354520 | 7 | 35 | 3666_3747 | 1362.0 | 3932.0 | Domain | FYR C-terminal | |
| Tgene | KMT2A | chr4:88005317 | chr11:118354896 | ENST00000354520 | 7 | 35 | 3829_3945 | 1362.0 | 3932.0 | Domain | SET | |
| Tgene | KMT2A | chr4:88005317 | chr11:118354896 | ENST00000354520 | 7 | 35 | 3953_3969 | 1362.0 | 3932.0 | Domain | Post-SET | |
| Tgene | KMT2A | chr4:88005317 | chr11:118354896 | ENST00000389506 | 7 | 36 | 1703_1748 | 1362.0 | 3970.0 | Domain | Bromo%3B divergent | |
| Tgene | KMT2A | chr4:88005317 | chr11:118354896 | ENST00000389506 | 7 | 36 | 2018_2074 | 1362.0 | 3970.0 | Domain | FYR N-terminal | |
| Tgene | KMT2A | chr4:88005317 | chr11:118354896 | ENST00000389506 | 7 | 36 | 3666_3747 | 1362.0 | 3970.0 | Domain | FYR C-terminal | |
| Tgene | KMT2A | chr4:88005317 | chr11:118354896 | ENST00000389506 | 7 | 36 | 3829_3945 | 1362.0 | 3970.0 | Domain | SET | |
| Tgene | KMT2A | chr4:88005317 | chr11:118354896 | ENST00000389506 | 7 | 36 | 3953_3969 | 1362.0 | 3970.0 | Domain | Post-SET | |
| Tgene | KMT2A | chr4:88005317 | chr11:118354896 | ENST00000534358 | 7 | 36 | 1703_1748 | 1362.0 | 3973.0 | Domain | Bromo%3B divergent | |
| Tgene | KMT2A | chr4:88005317 | chr11:118354896 | ENST00000534358 | 7 | 36 | 2018_2074 | 1362.0 | 3973.0 | Domain | FYR N-terminal | |
| Tgene | KMT2A | chr4:88005317 | chr11:118354896 | ENST00000534358 | 7 | 36 | 3666_3747 | 1362.0 | 3973.0 | Domain | FYR C-terminal | |
| Tgene | KMT2A | chr4:88005317 | chr11:118354896 | ENST00000534358 | 7 | 36 | 3829_3945 | 1362.0 | 3973.0 | Domain | SET | |
| Tgene | KMT2A | chr4:88005317 | chr11:118354896 | ENST00000534358 | 7 | 36 | 3953_3969 | 1362.0 | 3973.0 | Domain | Post-SET | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000354520 | 7 | 35 | 1663_1713 | 1362.0 | 3932.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000354520 | 7 | 35 | 1806_1869 | 1362.0 | 3932.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000354520 | 7 | 35 | 2081_2133 | 1362.0 | 3932.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000354520 | 7 | 35 | 2145_2232 | 1362.0 | 3932.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000354520 | 7 | 35 | 2275_2333 | 1362.0 | 3932.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000354520 | 7 | 35 | 2373_2460 | 1362.0 | 3932.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000354520 | 7 | 35 | 2475_2618 | 1362.0 | 3932.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000354520 | 7 | 35 | 2647_2675 | 1362.0 | 3932.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000354520 | 7 | 35 | 2713_2821 | 1362.0 | 3932.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000354520 | 7 | 35 | 2961_3064 | 1362.0 | 3932.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000354520 | 7 | 35 | 3166_3244 | 1362.0 | 3932.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000354520 | 7 | 35 | 3464_3608 | 1362.0 | 3932.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000354520 | 7 | 35 | 3620_3643 | 1362.0 | 3932.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000354520 | 7 | 35 | 3785_3808 | 1362.0 | 3932.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000354520 | 7 | 35 | 3906_3907 | 1362.0 | 3932.0 | Region | S-adenosyl-L-methionine binding | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000389506 | 7 | 36 | 1663_1713 | 1362.0 | 3970.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000389506 | 7 | 36 | 1806_1869 | 1362.0 | 3970.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000389506 | 7 | 36 | 2081_2133 | 1362.0 | 3970.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000389506 | 7 | 36 | 2145_2232 | 1362.0 | 3970.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000389506 | 7 | 36 | 2275_2333 | 1362.0 | 3970.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000389506 | 7 | 36 | 2373_2460 | 1362.0 | 3970.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000389506 | 7 | 36 | 2475_2618 | 1362.0 | 3970.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000389506 | 7 | 36 | 2647_2675 | 1362.0 | 3970.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000389506 | 7 | 36 | 2713_2821 | 1362.0 | 3970.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000389506 | 7 | 36 | 2961_3064 | 1362.0 | 3970.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000389506 | 7 | 36 | 3166_3244 | 1362.0 | 3970.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000389506 | 7 | 36 | 3464_3608 | 1362.0 | 3970.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000389506 | 7 | 36 | 3620_3643 | 1362.0 | 3970.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000389506 | 7 | 36 | 3785_3808 | 1362.0 | 3970.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000389506 | 7 | 36 | 3906_3907 | 1362.0 | 3970.0 | Region | S-adenosyl-L-methionine binding | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000534358 | 7 | 36 | 1663_1713 | 1362.0 | 3973.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000534358 | 7 | 36 | 1806_1869 | 1362.0 | 3973.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000534358 | 7 | 36 | 2081_2133 | 1362.0 | 3973.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000534358 | 7 | 36 | 2145_2232 | 1362.0 | 3973.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000534358 | 7 | 36 | 2275_2333 | 1362.0 | 3973.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000534358 | 7 | 36 | 2373_2460 | 1362.0 | 3973.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000534358 | 7 | 36 | 2475_2618 | 1362.0 | 3973.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000534358 | 7 | 36 | 2647_2675 | 1362.0 | 3973.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000534358 | 7 | 36 | 2713_2821 | 1362.0 | 3973.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000534358 | 7 | 36 | 2961_3064 | 1362.0 | 3973.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000534358 | 7 | 36 | 3166_3244 | 1362.0 | 3973.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000534358 | 7 | 36 | 3464_3608 | 1362.0 | 3973.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000534358 | 7 | 36 | 3620_3643 | 1362.0 | 3973.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000534358 | 7 | 36 | 3785_3808 | 1362.0 | 3973.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000534358 | 7 | 36 | 3906_3907 | 1362.0 | 3973.0 | Region | S-adenosyl-L-methionine binding | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000354520 | 8 | 35 | 1663_1713 | 1406.0 | 3932.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000354520 | 8 | 35 | 1806_1869 | 1406.0 | 3932.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000354520 | 8 | 35 | 2081_2133 | 1406.0 | 3932.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000354520 | 8 | 35 | 2145_2232 | 1406.0 | 3932.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000354520 | 8 | 35 | 2275_2333 | 1406.0 | 3932.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000354520 | 8 | 35 | 2373_2460 | 1406.0 | 3932.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000354520 | 8 | 35 | 2475_2618 | 1406.0 | 3932.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000354520 | 8 | 35 | 2647_2675 | 1406.0 | 3932.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000354520 | 8 | 35 | 2713_2821 | 1406.0 | 3932.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000354520 | 8 | 35 | 2961_3064 | 1406.0 | 3932.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000354520 | 8 | 35 | 3166_3244 | 1406.0 | 3932.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000354520 | 8 | 35 | 3464_3608 | 1406.0 | 3932.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000354520 | 8 | 35 | 3620_3643 | 1406.0 | 3932.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000354520 | 8 | 35 | 3785_3808 | 1406.0 | 3932.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000354520 | 8 | 35 | 3906_3907 | 1406.0 | 3932.0 | Region | S-adenosyl-L-methionine binding | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000389506 | 9 | 36 | 1663_1713 | 1444.0 | 3970.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000389506 | 9 | 36 | 1806_1869 | 1444.0 | 3970.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000389506 | 9 | 36 | 2081_2133 | 1444.0 | 3970.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000389506 | 9 | 36 | 2145_2232 | 1444.0 | 3970.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000389506 | 9 | 36 | 2275_2333 | 1444.0 | 3970.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000389506 | 9 | 36 | 2373_2460 | 1444.0 | 3970.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000389506 | 9 | 36 | 2475_2618 | 1444.0 | 3970.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000389506 | 9 | 36 | 2647_2675 | 1444.0 | 3970.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000389506 | 9 | 36 | 2713_2821 | 1444.0 | 3970.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000389506 | 9 | 36 | 2961_3064 | 1444.0 | 3970.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000389506 | 9 | 36 | 3166_3244 | 1444.0 | 3970.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000389506 | 9 | 36 | 3464_3608 | 1444.0 | 3970.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000389506 | 9 | 36 | 3620_3643 | 1444.0 | 3970.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000389506 | 9 | 36 | 3785_3808 | 1444.0 | 3970.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000389506 | 9 | 36 | 3906_3907 | 1444.0 | 3970.0 | Region | S-adenosyl-L-methionine binding | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000534358 | 9 | 36 | 1663_1713 | 1444.0 | 3973.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000534358 | 9 | 36 | 1806_1869 | 1444.0 | 3973.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000534358 | 9 | 36 | 2081_2133 | 1444.0 | 3973.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000534358 | 9 | 36 | 2145_2232 | 1444.0 | 3973.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000534358 | 9 | 36 | 2275_2333 | 1444.0 | 3973.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000534358 | 9 | 36 | 2373_2460 | 1444.0 | 3973.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000534358 | 9 | 36 | 2475_2618 | 1444.0 | 3973.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000534358 | 9 | 36 | 2647_2675 | 1444.0 | 3973.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000534358 | 9 | 36 | 2713_2821 | 1444.0 | 3973.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000534358 | 9 | 36 | 2961_3064 | 1444.0 | 3973.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000534358 | 9 | 36 | 3166_3244 | 1444.0 | 3973.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000534358 | 9 | 36 | 3464_3608 | 1444.0 | 3973.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000534358 | 9 | 36 | 3620_3643 | 1444.0 | 3973.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000534358 | 9 | 36 | 3785_3808 | 1444.0 | 3973.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000534358 | 9 | 36 | 3906_3907 | 1444.0 | 3973.0 | Region | S-adenosyl-L-methionine binding | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000354520 | 7 | 35 | 1663_1713 | 1362.0 | 3932.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000354520 | 7 | 35 | 1806_1869 | 1362.0 | 3932.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000354520 | 7 | 35 | 2081_2133 | 1362.0 | 3932.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000354520 | 7 | 35 | 2145_2232 | 1362.0 | 3932.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000354520 | 7 | 35 | 2275_2333 | 1362.0 | 3932.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000354520 | 7 | 35 | 2373_2460 | 1362.0 | 3932.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000354520 | 7 | 35 | 2475_2618 | 1362.0 | 3932.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000354520 | 7 | 35 | 2647_2675 | 1362.0 | 3932.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000354520 | 7 | 35 | 2713_2821 | 1362.0 | 3932.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000354520 | 7 | 35 | 2961_3064 | 1362.0 | 3932.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000354520 | 7 | 35 | 3166_3244 | 1362.0 | 3932.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000354520 | 7 | 35 | 3464_3608 | 1362.0 | 3932.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000354520 | 7 | 35 | 3620_3643 | 1362.0 | 3932.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000354520 | 7 | 35 | 3785_3808 | 1362.0 | 3932.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000354520 | 7 | 35 | 3906_3907 | 1362.0 | 3932.0 | Region | S-adenosyl-L-methionine binding | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000389506 | 7 | 36 | 1663_1713 | 1362.0 | 3970.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000389506 | 7 | 36 | 1806_1869 | 1362.0 | 3970.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000389506 | 7 | 36 | 2081_2133 | 1362.0 | 3970.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000389506 | 7 | 36 | 2145_2232 | 1362.0 | 3970.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000389506 | 7 | 36 | 2275_2333 | 1362.0 | 3970.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000389506 | 7 | 36 | 2373_2460 | 1362.0 | 3970.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000389506 | 7 | 36 | 2475_2618 | 1362.0 | 3970.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000389506 | 7 | 36 | 2647_2675 | 1362.0 | 3970.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000389506 | 7 | 36 | 2713_2821 | 1362.0 | 3970.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000389506 | 7 | 36 | 2961_3064 | 1362.0 | 3970.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000389506 | 7 | 36 | 3166_3244 | 1362.0 | 3970.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000389506 | 7 | 36 | 3464_3608 | 1362.0 | 3970.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000389506 | 7 | 36 | 3620_3643 | 1362.0 | 3970.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000389506 | 7 | 36 | 3785_3808 | 1362.0 | 3970.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000389506 | 7 | 36 | 3906_3907 | 1362.0 | 3970.0 | Region | S-adenosyl-L-methionine binding | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000534358 | 7 | 36 | 1663_1713 | 1362.0 | 3973.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000534358 | 7 | 36 | 1806_1869 | 1362.0 | 3973.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000534358 | 7 | 36 | 2081_2133 | 1362.0 | 3973.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000534358 | 7 | 36 | 2145_2232 | 1362.0 | 3973.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000534358 | 7 | 36 | 2275_2333 | 1362.0 | 3973.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000534358 | 7 | 36 | 2373_2460 | 1362.0 | 3973.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000534358 | 7 | 36 | 2475_2618 | 1362.0 | 3973.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000534358 | 7 | 36 | 2647_2675 | 1362.0 | 3973.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000534358 | 7 | 36 | 2713_2821 | 1362.0 | 3973.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000534358 | 7 | 36 | 2961_3064 | 1362.0 | 3973.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000534358 | 7 | 36 | 3166_3244 | 1362.0 | 3973.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000534358 | 7 | 36 | 3464_3608 | 1362.0 | 3973.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000534358 | 7 | 36 | 3620_3643 | 1362.0 | 3973.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000534358 | 7 | 36 | 3785_3808 | 1362.0 | 3973.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000534358 | 7 | 36 | 3906_3907 | 1362.0 | 3973.0 | Region | S-adenosyl-L-methionine binding | |
| Tgene | KMT2A | chr4:87968747 | chr11:118354896 | ENST00000354520 | 7 | 35 | 3906_3907 | 1362.0 | 3932.0 | Region | S-adenosyl-L-methionine binding | |
| Tgene | KMT2A | chr4:87968747 | chr11:118354896 | ENST00000389506 | 7 | 36 | 3906_3907 | 1362.0 | 3970.0 | Region | S-adenosyl-L-methionine binding | |
| Tgene | KMT2A | chr4:87968747 | chr11:118354896 | ENST00000534358 | 7 | 36 | 3906_3907 | 1362.0 | 3973.0 | Region | S-adenosyl-L-methionine binding | |
| Tgene | KMT2A | chr4:87968752 | chr11:118359327 | ENST00000354520 | 8 | 35 | 3906_3907 | 1406.0 | 3932.0 | Region | S-adenosyl-L-methionine binding | |
| Tgene | KMT2A | chr4:87968752 | chr11:118359327 | ENST00000389506 | 9 | 36 | 3906_3907 | 1444.0 | 3970.0 | Region | S-adenosyl-L-methionine binding | |
| Tgene | KMT2A | chr4:87968752 | chr11:118359327 | ENST00000534358 | 9 | 36 | 3906_3907 | 1444.0 | 3973.0 | Region | S-adenosyl-L-methionine binding | |
| Tgene | KMT2A | chr4:88005317 | chr11:118354896 | ENST00000354520 | 7 | 35 | 3906_3907 | 1362.0 | 3932.0 | Region | S-adenosyl-L-methionine binding | |
| Tgene | KMT2A | chr4:88005317 | chr11:118354896 | ENST00000389506 | 7 | 36 | 3906_3907 | 1362.0 | 3970.0 | Region | S-adenosyl-L-methionine binding | |
| Tgene | KMT2A | chr4:88005317 | chr11:118354896 | ENST00000534358 | 7 | 36 | 3906_3907 | 1362.0 | 3973.0 | Region | S-adenosyl-L-methionine binding | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000354520 | 7 | 35 | 1431_1482 | 1362.0 | 3932.0 | Zinc finger | PHD-type 1 | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000354520 | 7 | 35 | 1479_1533 | 1362.0 | 3932.0 | Zinc finger | PHD-type 2 | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000354520 | 7 | 35 | 1566_1627 | 1362.0 | 3932.0 | Zinc finger | PHD-type 3 | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000354520 | 7 | 35 | 1870_1910 | 1362.0 | 3932.0 | Zinc finger | C2HC pre-PHD-type | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000354520 | 7 | 35 | 1931_1978 | 1362.0 | 3932.0 | Zinc finger | PHD-type 4 | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000389506 | 7 | 36 | 1431_1482 | 1362.0 | 3970.0 | Zinc finger | PHD-type 1 | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000389506 | 7 | 36 | 1479_1533 | 1362.0 | 3970.0 | Zinc finger | PHD-type 2 | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000389506 | 7 | 36 | 1566_1627 | 1362.0 | 3970.0 | Zinc finger | PHD-type 3 | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000389506 | 7 | 36 | 1870_1910 | 1362.0 | 3970.0 | Zinc finger | C2HC pre-PHD-type | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000389506 | 7 | 36 | 1931_1978 | 1362.0 | 3970.0 | Zinc finger | PHD-type 4 | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000534358 | 7 | 36 | 1431_1482 | 1362.0 | 3973.0 | Zinc finger | PHD-type 1 | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000534358 | 7 | 36 | 1479_1533 | 1362.0 | 3973.0 | Zinc finger | PHD-type 2 | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000534358 | 7 | 36 | 1566_1627 | 1362.0 | 3973.0 | Zinc finger | PHD-type 3 | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000534358 | 7 | 36 | 1870_1910 | 1362.0 | 3973.0 | Zinc finger | C2HC pre-PHD-type | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000534358 | 7 | 36 | 1931_1978 | 1362.0 | 3973.0 | Zinc finger | PHD-type 4 | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000354520 | 8 | 35 | 1431_1482 | 1406.0 | 3932.0 | Zinc finger | PHD-type 1 | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000354520 | 8 | 35 | 1479_1533 | 1406.0 | 3932.0 | Zinc finger | PHD-type 2 | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000354520 | 8 | 35 | 1566_1627 | 1406.0 | 3932.0 | Zinc finger | PHD-type 3 | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000354520 | 8 | 35 | 1870_1910 | 1406.0 | 3932.0 | Zinc finger | C2HC pre-PHD-type | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000354520 | 8 | 35 | 1931_1978 | 1406.0 | 3932.0 | Zinc finger | PHD-type 4 | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000389506 | 9 | 36 | 1479_1533 | 1444.0 | 3970.0 | Zinc finger | PHD-type 2 | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000389506 | 9 | 36 | 1566_1627 | 1444.0 | 3970.0 | Zinc finger | PHD-type 3 | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000389506 | 9 | 36 | 1870_1910 | 1444.0 | 3970.0 | Zinc finger | C2HC pre-PHD-type | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000389506 | 9 | 36 | 1931_1978 | 1444.0 | 3970.0 | Zinc finger | PHD-type 4 | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000534358 | 9 | 36 | 1479_1533 | 1444.0 | 3973.0 | Zinc finger | PHD-type 2 | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000534358 | 9 | 36 | 1566_1627 | 1444.0 | 3973.0 | Zinc finger | PHD-type 3 | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000534358 | 9 | 36 | 1870_1910 | 1444.0 | 3973.0 | Zinc finger | C2HC pre-PHD-type | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000534358 | 9 | 36 | 1931_1978 | 1444.0 | 3973.0 | Zinc finger | PHD-type 4 | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000354520 | 7 | 35 | 1431_1482 | 1362.0 | 3932.0 | Zinc finger | PHD-type 1 | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000354520 | 7 | 35 | 1479_1533 | 1362.0 | 3932.0 | Zinc finger | PHD-type 2 | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000354520 | 7 | 35 | 1566_1627 | 1362.0 | 3932.0 | Zinc finger | PHD-type 3 | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000354520 | 7 | 35 | 1870_1910 | 1362.0 | 3932.0 | Zinc finger | C2HC pre-PHD-type | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000354520 | 7 | 35 | 1931_1978 | 1362.0 | 3932.0 | Zinc finger | PHD-type 4 | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000389506 | 7 | 36 | 1431_1482 | 1362.0 | 3970.0 | Zinc finger | PHD-type 1 | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000389506 | 7 | 36 | 1479_1533 | 1362.0 | 3970.0 | Zinc finger | PHD-type 2 | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000389506 | 7 | 36 | 1566_1627 | 1362.0 | 3970.0 | Zinc finger | PHD-type 3 | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000389506 | 7 | 36 | 1870_1910 | 1362.0 | 3970.0 | Zinc finger | C2HC pre-PHD-type | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000389506 | 7 | 36 | 1931_1978 | 1362.0 | 3970.0 | Zinc finger | PHD-type 4 | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000534358 | 7 | 36 | 1431_1482 | 1362.0 | 3973.0 | Zinc finger | PHD-type 1 | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000534358 | 7 | 36 | 1479_1533 | 1362.0 | 3973.0 | Zinc finger | PHD-type 2 | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000534358 | 7 | 36 | 1566_1627 | 1362.0 | 3973.0 | Zinc finger | PHD-type 3 | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000534358 | 7 | 36 | 1870_1910 | 1362.0 | 3973.0 | Zinc finger | C2HC pre-PHD-type | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000534358 | 7 | 36 | 1931_1978 | 1362.0 | 3973.0 | Zinc finger | PHD-type 4 | |
| Tgene | KMT2A | chr4:87968747 | chr11:118354896 | ENST00000354520 | 7 | 35 | 1431_1482 | 1362.0 | 3932.0 | Zinc finger | PHD-type 1 | |
| Tgene | KMT2A | chr4:87968747 | chr11:118354896 | ENST00000354520 | 7 | 35 | 1479_1533 | 1362.0 | 3932.0 | Zinc finger | PHD-type 2 | |
| Tgene | KMT2A | chr4:87968747 | chr11:118354896 | ENST00000354520 | 7 | 35 | 1566_1627 | 1362.0 | 3932.0 | Zinc finger | PHD-type 3 | |
| Tgene | KMT2A | chr4:87968747 | chr11:118354896 | ENST00000354520 | 7 | 35 | 1870_1910 | 1362.0 | 3932.0 | Zinc finger | C2HC pre-PHD-type | |
| Tgene | KMT2A | chr4:87968747 | chr11:118354896 | ENST00000354520 | 7 | 35 | 1931_1978 | 1362.0 | 3932.0 | Zinc finger | PHD-type 4 | |
| Tgene | KMT2A | chr4:87968747 | chr11:118354896 | ENST00000389506 | 7 | 36 | 1431_1482 | 1362.0 | 3970.0 | Zinc finger | PHD-type 1 | |
| Tgene | KMT2A | chr4:87968747 | chr11:118354896 | ENST00000389506 | 7 | 36 | 1479_1533 | 1362.0 | 3970.0 | Zinc finger | PHD-type 2 | |
| Tgene | KMT2A | chr4:87968747 | chr11:118354896 | ENST00000389506 | 7 | 36 | 1566_1627 | 1362.0 | 3970.0 | Zinc finger | PHD-type 3 | |
| Tgene | KMT2A | chr4:87968747 | chr11:118354896 | ENST00000389506 | 7 | 36 | 1870_1910 | 1362.0 | 3970.0 | Zinc finger | C2HC pre-PHD-type | |
| Tgene | KMT2A | chr4:87968747 | chr11:118354896 | ENST00000389506 | 7 | 36 | 1931_1978 | 1362.0 | 3970.0 | Zinc finger | PHD-type 4 | |
| Tgene | KMT2A | chr4:87968747 | chr11:118354896 | ENST00000534358 | 7 | 36 | 1431_1482 | 1362.0 | 3973.0 | Zinc finger | PHD-type 1 | |
| Tgene | KMT2A | chr4:87968747 | chr11:118354896 | ENST00000534358 | 7 | 36 | 1479_1533 | 1362.0 | 3973.0 | Zinc finger | PHD-type 2 | |
| Tgene | KMT2A | chr4:87968747 | chr11:118354896 | ENST00000534358 | 7 | 36 | 1566_1627 | 1362.0 | 3973.0 | Zinc finger | PHD-type 3 | |
| Tgene | KMT2A | chr4:87968747 | chr11:118354896 | ENST00000534358 | 7 | 36 | 1870_1910 | 1362.0 | 3973.0 | Zinc finger | C2HC pre-PHD-type | |
| Tgene | KMT2A | chr4:87968747 | chr11:118354896 | ENST00000534358 | 7 | 36 | 1931_1978 | 1362.0 | 3973.0 | Zinc finger | PHD-type 4 | |
| Tgene | KMT2A | chr4:87968752 | chr11:118359327 | ENST00000354520 | 8 | 35 | 1431_1482 | 1406.0 | 3932.0 | Zinc finger | PHD-type 1 | |
| Tgene | KMT2A | chr4:87968752 | chr11:118359327 | ENST00000354520 | 8 | 35 | 1479_1533 | 1406.0 | 3932.0 | Zinc finger | PHD-type 2 | |
| Tgene | KMT2A | chr4:87968752 | chr11:118359327 | ENST00000354520 | 8 | 35 | 1566_1627 | 1406.0 | 3932.0 | Zinc finger | PHD-type 3 | |
| Tgene | KMT2A | chr4:87968752 | chr11:118359327 | ENST00000354520 | 8 | 35 | 1870_1910 | 1406.0 | 3932.0 | Zinc finger | C2HC pre-PHD-type | |
| Tgene | KMT2A | chr4:87968752 | chr11:118359327 | ENST00000354520 | 8 | 35 | 1931_1978 | 1406.0 | 3932.0 | Zinc finger | PHD-type 4 | |
| Tgene | KMT2A | chr4:87968752 | chr11:118359327 | ENST00000389506 | 9 | 36 | 1479_1533 | 1444.0 | 3970.0 | Zinc finger | PHD-type 2 | |
| Tgene | KMT2A | chr4:87968752 | chr11:118359327 | ENST00000389506 | 9 | 36 | 1566_1627 | 1444.0 | 3970.0 | Zinc finger | PHD-type 3 | |
| Tgene | KMT2A | chr4:87968752 | chr11:118359327 | ENST00000389506 | 9 | 36 | 1870_1910 | 1444.0 | 3970.0 | Zinc finger | C2HC pre-PHD-type | |
| Tgene | KMT2A | chr4:87968752 | chr11:118359327 | ENST00000389506 | 9 | 36 | 1931_1978 | 1444.0 | 3970.0 | Zinc finger | PHD-type 4 | |
| Tgene | KMT2A | chr4:87968752 | chr11:118359327 | ENST00000534358 | 9 | 36 | 1479_1533 | 1444.0 | 3973.0 | Zinc finger | PHD-type 2 | |
| Tgene | KMT2A | chr4:87968752 | chr11:118359327 | ENST00000534358 | 9 | 36 | 1566_1627 | 1444.0 | 3973.0 | Zinc finger | PHD-type 3 | |
| Tgene | KMT2A | chr4:87968752 | chr11:118359327 | ENST00000534358 | 9 | 36 | 1870_1910 | 1444.0 | 3973.0 | Zinc finger | C2HC pre-PHD-type | |
| Tgene | KMT2A | chr4:87968752 | chr11:118359327 | ENST00000534358 | 9 | 36 | 1931_1978 | 1444.0 | 3973.0 | Zinc finger | PHD-type 4 | |
| Tgene | KMT2A | chr4:88005317 | chr11:118354896 | ENST00000354520 | 7 | 35 | 1431_1482 | 1362.0 | 3932.0 | Zinc finger | PHD-type 1 | |
| Tgene | KMT2A | chr4:88005317 | chr11:118354896 | ENST00000354520 | 7 | 35 | 1479_1533 | 1362.0 | 3932.0 | Zinc finger | PHD-type 2 | |
| Tgene | KMT2A | chr4:88005317 | chr11:118354896 | ENST00000354520 | 7 | 35 | 1566_1627 | 1362.0 | 3932.0 | Zinc finger | PHD-type 3 | |
| Tgene | KMT2A | chr4:88005317 | chr11:118354896 | ENST00000354520 | 7 | 35 | 1870_1910 | 1362.0 | 3932.0 | Zinc finger | C2HC pre-PHD-type | |
| Tgene | KMT2A | chr4:88005317 | chr11:118354896 | ENST00000354520 | 7 | 35 | 1931_1978 | 1362.0 | 3932.0 | Zinc finger | PHD-type 4 | |
| Tgene | KMT2A | chr4:88005317 | chr11:118354896 | ENST00000389506 | 7 | 36 | 1431_1482 | 1362.0 | 3970.0 | Zinc finger | PHD-type 1 | |
| Tgene | KMT2A | chr4:88005317 | chr11:118354896 | ENST00000389506 | 7 | 36 | 1479_1533 | 1362.0 | 3970.0 | Zinc finger | PHD-type 2 | |
| Tgene | KMT2A | chr4:88005317 | chr11:118354896 | ENST00000389506 | 7 | 36 | 1566_1627 | 1362.0 | 3970.0 | Zinc finger | PHD-type 3 | |
| Tgene | KMT2A | chr4:88005317 | chr11:118354896 | ENST00000389506 | 7 | 36 | 1870_1910 | 1362.0 | 3970.0 | Zinc finger | C2HC pre-PHD-type | |
| Tgene | KMT2A | chr4:88005317 | chr11:118354896 | ENST00000389506 | 7 | 36 | 1931_1978 | 1362.0 | 3970.0 | Zinc finger | PHD-type 4 | |
| Tgene | KMT2A | chr4:88005317 | chr11:118354896 | ENST00000534358 | 7 | 36 | 1431_1482 | 1362.0 | 3973.0 | Zinc finger | PHD-type 1 | |
| Tgene | KMT2A | chr4:88005317 | chr11:118354896 | ENST00000534358 | 7 | 36 | 1479_1533 | 1362.0 | 3973.0 | Zinc finger | PHD-type 2 | |
| Tgene | KMT2A | chr4:88005317 | chr11:118354896 | ENST00000534358 | 7 | 36 | 1566_1627 | 1362.0 | 3973.0 | Zinc finger | PHD-type 3 | |
| Tgene | KMT2A | chr4:88005317 | chr11:118354896 | ENST00000534358 | 7 | 36 | 1870_1910 | 1362.0 | 3973.0 | Zinc finger | C2HC pre-PHD-type | |
| Tgene | KMT2A | chr4:88005317 | chr11:118354896 | ENST00000534358 | 7 | 36 | 1931_1978 | 1362.0 | 3973.0 | Zinc finger | PHD-type 4 |
| - Not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | AFF1 | chr4:87967438 | chr11:118354897 | ENST00000307808 | 2 | 20 | 168_191 | 46.0 | 1211.0 | Compositional bias | Basic and acidic residues | |
| Hgene | AFF1 | chr4:87967438 | chr11:118354897 | ENST00000307808 | 2 | 20 | 213_241 | 46.0 | 1211.0 | Compositional bias | Polar residues | |
| Hgene | AFF1 | chr4:87967438 | chr11:118354897 | ENST00000307808 | 2 | 20 | 371_426 | 46.0 | 1211.0 | Compositional bias | Polar residues | |
| Hgene | AFF1 | chr4:87967438 | chr11:118354897 | ENST00000307808 | 2 | 20 | 459_486 | 46.0 | 1211.0 | Compositional bias | Polar residues | |
| Hgene | AFF1 | chr4:87967438 | chr11:118354897 | ENST00000307808 | 2 | 20 | 585_605 | 46.0 | 1211.0 | Compositional bias | Polar residues | |
| Hgene | AFF1 | chr4:87967438 | chr11:118354897 | ENST00000307808 | 2 | 20 | 710_728 | 46.0 | 1211.0 | Compositional bias | Polar residues | |
| Hgene | AFF1 | chr4:87967438 | chr11:118354897 | ENST00000307808 | 2 | 20 | 781_833 | 46.0 | 1211.0 | Compositional bias | Basic and acidic residues | |
| Hgene | AFF1 | chr4:87967438 | chr11:118354897 | ENST00000307808 | 2 | 20 | 834_879 | 46.0 | 1211.0 | Compositional bias | Polar residues | |
| Hgene | AFF1 | chr4:87967438 | chr11:118354897 | ENST00000307808 | 2 | 20 | 909_928 | 46.0 | 1211.0 | Compositional bias | Basic and acidic residues | |
| Hgene | AFF1 | chr4:87967438 | chr11:118354897 | ENST00000307808 | 2 | 20 | 929_944 | 46.0 | 1211.0 | Compositional bias | Polar residues | |
| Hgene | AFF1 | chr4:87967438 | chr11:118354897 | ENST00000307808 | 2 | 20 | 99_135 | 46.0 | 1211.0 | Compositional bias | Polar residues | |
| Hgene | AFF1 | chr4:87967438 | chr11:118354897 | ENST00000395146 | 3 | 21 | 168_191 | 53.0 | 1219.0 | Compositional bias | Basic and acidic residues | |
| Hgene | AFF1 | chr4:87967438 | chr11:118354897 | ENST00000395146 | 3 | 21 | 213_241 | 53.0 | 1219.0 | Compositional bias | Polar residues | |
| Hgene | AFF1 | chr4:87967438 | chr11:118354897 | ENST00000395146 | 3 | 21 | 371_426 | 53.0 | 1219.0 | Compositional bias | Polar residues | |
| Hgene | AFF1 | chr4:87967438 | chr11:118354897 | ENST00000395146 | 3 | 21 | 459_486 | 53.0 | 1219.0 | Compositional bias | Polar residues | |
| Hgene | AFF1 | chr4:87967438 | chr11:118354897 | ENST00000395146 | 3 | 21 | 585_605 | 53.0 | 1219.0 | Compositional bias | Polar residues | |
| Hgene | AFF1 | chr4:87967438 | chr11:118354897 | ENST00000395146 | 3 | 21 | 710_728 | 53.0 | 1219.0 | Compositional bias | Polar residues | |
| Hgene | AFF1 | chr4:87967438 | chr11:118354897 | ENST00000395146 | 3 | 21 | 781_833 | 53.0 | 1219.0 | Compositional bias | Basic and acidic residues | |
| Hgene | AFF1 | chr4:87967438 | chr11:118354897 | ENST00000395146 | 3 | 21 | 834_879 | 53.0 | 1219.0 | Compositional bias | Polar residues | |
| Hgene | AFF1 | chr4:87967438 | chr11:118354897 | ENST00000395146 | 3 | 21 | 909_928 | 53.0 | 1219.0 | Compositional bias | Basic and acidic residues | |
| Hgene | AFF1 | chr4:87967438 | chr11:118354897 | ENST00000395146 | 3 | 21 | 929_944 | 53.0 | 1219.0 | Compositional bias | Polar residues | |
| Hgene | AFF1 | chr4:87967438 | chr11:118354897 | ENST00000395146 | 3 | 21 | 99_135 | 53.0 | 1219.0 | Compositional bias | Polar residues | |
| Hgene | AFF1 | chr4:87967438 | chr11:118359328 | ENST00000307808 | 2 | 20 | 168_191 | 46.0 | 1211.0 | Compositional bias | Basic and acidic residues | |
| Hgene | AFF1 | chr4:87967438 | chr11:118359328 | ENST00000307808 | 2 | 20 | 213_241 | 46.0 | 1211.0 | Compositional bias | Polar residues | |
| Hgene | AFF1 | chr4:87967438 | chr11:118359328 | ENST00000307808 | 2 | 20 | 371_426 | 46.0 | 1211.0 | Compositional bias | Polar residues | |
| Hgene | AFF1 | chr4:87967438 | chr11:118359328 | ENST00000307808 | 2 | 20 | 459_486 | 46.0 | 1211.0 | Compositional bias | Polar residues | |
| Hgene | AFF1 | chr4:87967438 | chr11:118359328 | ENST00000307808 | 2 | 20 | 585_605 | 46.0 | 1211.0 | Compositional bias | Polar residues | |
| Hgene | AFF1 | chr4:87967438 | chr11:118359328 | ENST00000307808 | 2 | 20 | 710_728 | 46.0 | 1211.0 | Compositional bias | Polar residues | |
| Hgene | AFF1 | chr4:87967438 | chr11:118359328 | ENST00000307808 | 2 | 20 | 781_833 | 46.0 | 1211.0 | Compositional bias | Basic and acidic residues | |
| Hgene | AFF1 | chr4:87967438 | chr11:118359328 | ENST00000307808 | 2 | 20 | 834_879 | 46.0 | 1211.0 | Compositional bias | Polar residues | |
| Hgene | AFF1 | chr4:87967438 | chr11:118359328 | ENST00000307808 | 2 | 20 | 909_928 | 46.0 | 1211.0 | Compositional bias | Basic and acidic residues | |
| Hgene | AFF1 | chr4:87967438 | chr11:118359328 | ENST00000307808 | 2 | 20 | 929_944 | 46.0 | 1211.0 | Compositional bias | Polar residues | |
| Hgene | AFF1 | chr4:87967438 | chr11:118359328 | ENST00000307808 | 2 | 20 | 99_135 | 46.0 | 1211.0 | Compositional bias | Polar residues | |
| Hgene | AFF1 | chr4:87967438 | chr11:118359328 | ENST00000395146 | 3 | 21 | 168_191 | 53.0 | 1219.0 | Compositional bias | Basic and acidic residues | |
| Hgene | AFF1 | chr4:87967438 | chr11:118359328 | ENST00000395146 | 3 | 21 | 213_241 | 53.0 | 1219.0 | Compositional bias | Polar residues | |
| Hgene | AFF1 | chr4:87967438 | chr11:118359328 | ENST00000395146 | 3 | 21 | 371_426 | 53.0 | 1219.0 | Compositional bias | Polar residues | |
| Hgene | AFF1 | chr4:87967438 | chr11:118359328 | ENST00000395146 | 3 | 21 | 459_486 | 53.0 | 1219.0 | Compositional bias | Polar residues | |
| Hgene | AFF1 | chr4:87967438 | chr11:118359328 | ENST00000395146 | 3 | 21 | 585_605 | 53.0 | 1219.0 | Compositional bias | Polar residues | |
| Hgene | AFF1 | chr4:87967438 | chr11:118359328 | ENST00000395146 | 3 | 21 | 710_728 | 53.0 | 1219.0 | Compositional bias | Polar residues | |
| Hgene | AFF1 | chr4:87967438 | chr11:118359328 | ENST00000395146 | 3 | 21 | 781_833 | 53.0 | 1219.0 | Compositional bias | Basic and acidic residues | |
| Hgene | AFF1 | chr4:87967438 | chr11:118359328 | ENST00000395146 | 3 | 21 | 834_879 | 53.0 | 1219.0 | Compositional bias | Polar residues | |
| Hgene | AFF1 | chr4:87967438 | chr11:118359328 | ENST00000395146 | 3 | 21 | 909_928 | 53.0 | 1219.0 | Compositional bias | Basic and acidic residues | |
| Hgene | AFF1 | chr4:87967438 | chr11:118359328 | ENST00000395146 | 3 | 21 | 929_944 | 53.0 | 1219.0 | Compositional bias | Polar residues | |
| Hgene | AFF1 | chr4:87967438 | chr11:118359328 | ENST00000395146 | 3 | 21 | 99_135 | 53.0 | 1219.0 | Compositional bias | Polar residues | |
| Hgene | AFF1 | chr4:87968746 | chr11:118354897 | ENST00000307808 | 3 | 20 | 371_426 | 346.0 | 1211.0 | Compositional bias | Polar residues | |
| Hgene | AFF1 | chr4:87968746 | chr11:118354897 | ENST00000307808 | 3 | 20 | 459_486 | 346.0 | 1211.0 | Compositional bias | Polar residues | |
| Hgene | AFF1 | chr4:87968746 | chr11:118354897 | ENST00000307808 | 3 | 20 | 585_605 | 346.0 | 1211.0 | Compositional bias | Polar residues | |
| Hgene | AFF1 | chr4:87968746 | chr11:118354897 | ENST00000307808 | 3 | 20 | 710_728 | 346.0 | 1211.0 | Compositional bias | Polar residues | |
| Hgene | AFF1 | chr4:87968746 | chr11:118354897 | ENST00000307808 | 3 | 20 | 781_833 | 346.0 | 1211.0 | Compositional bias | Basic and acidic residues | |
| Hgene | AFF1 | chr4:87968746 | chr11:118354897 | ENST00000307808 | 3 | 20 | 834_879 | 346.0 | 1211.0 | Compositional bias | Polar residues | |
| Hgene | AFF1 | chr4:87968746 | chr11:118354897 | ENST00000307808 | 3 | 20 | 909_928 | 346.0 | 1211.0 | Compositional bias | Basic and acidic residues | |
| Hgene | AFF1 | chr4:87968746 | chr11:118354897 | ENST00000307808 | 3 | 20 | 929_944 | 346.0 | 1211.0 | Compositional bias | Polar residues | |
| Hgene | AFF1 | chr4:87968746 | chr11:118354897 | ENST00000395146 | 4 | 21 | 371_426 | 353.0 | 1219.0 | Compositional bias | Polar residues | |
| Hgene | AFF1 | chr4:87968746 | chr11:118354897 | ENST00000395146 | 4 | 21 | 459_486 | 353.0 | 1219.0 | Compositional bias | Polar residues | |
| Hgene | AFF1 | chr4:87968746 | chr11:118354897 | ENST00000395146 | 4 | 21 | 585_605 | 353.0 | 1219.0 | Compositional bias | Polar residues | |
| Hgene | AFF1 | chr4:87968746 | chr11:118354897 | ENST00000395146 | 4 | 21 | 710_728 | 353.0 | 1219.0 | Compositional bias | Polar residues | |
| Hgene | AFF1 | chr4:87968746 | chr11:118354897 | ENST00000395146 | 4 | 21 | 781_833 | 353.0 | 1219.0 | Compositional bias | Basic and acidic residues | |
| Hgene | AFF1 | chr4:87968746 | chr11:118354897 | ENST00000395146 | 4 | 21 | 834_879 | 353.0 | 1219.0 | Compositional bias | Polar residues | |
| Hgene | AFF1 | chr4:87968746 | chr11:118354897 | ENST00000395146 | 4 | 21 | 909_928 | 353.0 | 1219.0 | Compositional bias | Basic and acidic residues | |
| Hgene | AFF1 | chr4:87968746 | chr11:118354897 | ENST00000395146 | 4 | 21 | 929_944 | 353.0 | 1219.0 | Compositional bias | Polar residues | |
| Hgene | AFF1 | chr4:87968747 | chr11:118354896 | ENST00000307808 | + | 3 | 20 | 483_492 | 346.0 | 1211.0 | Compositional bias | Note=Poly-Ser |
| Hgene | AFF1 | chr4:87968747 | chr11:118354896 | ENST00000307808 | + | 3 | 20 | 835_843 | 346.0 | 1211.0 | Compositional bias | Note=Poly-Ser |
| Hgene | AFF1 | chr4:87968747 | chr11:118354896 | ENST00000307808 | + | 3 | 20 | 866_869 | 346.0 | 1211.0 | Compositional bias | Note=Poly-Pro |
| Hgene | AFF1 | chr4:87968747 | chr11:118354896 | ENST00000307808 | + | 3 | 20 | 871_874 | 346.0 | 1211.0 | Compositional bias | Note=Poly-Ser |
| Hgene | AFF1 | chr4:87968747 | chr11:118354896 | ENST00000395146 | + | 4 | 21 | 483_492 | 353.0 | 1219.0 | Compositional bias | Note=Poly-Ser |
| Hgene | AFF1 | chr4:87968747 | chr11:118354896 | ENST00000395146 | + | 4 | 21 | 835_843 | 353.0 | 1219.0 | Compositional bias | Note=Poly-Ser |
| Hgene | AFF1 | chr4:87968747 | chr11:118354896 | ENST00000395146 | + | 4 | 21 | 866_869 | 353.0 | 1219.0 | Compositional bias | Note=Poly-Pro |
| Hgene | AFF1 | chr4:87968747 | chr11:118354896 | ENST00000395146 | + | 4 | 21 | 871_874 | 353.0 | 1219.0 | Compositional bias | Note=Poly-Ser |
| Hgene | AFF1 | chr4:87968752 | chr11:118359327 | ENST00000307808 | + | 3 | 20 | 483_492 | 346.0 | 1211.0 | Compositional bias | Note=Poly-Ser |
| Hgene | AFF1 | chr4:87968752 | chr11:118359327 | ENST00000307808 | + | 3 | 20 | 835_843 | 346.0 | 1211.0 | Compositional bias | Note=Poly-Ser |
| Hgene | AFF1 | chr4:87968752 | chr11:118359327 | ENST00000307808 | + | 3 | 20 | 866_869 | 346.0 | 1211.0 | Compositional bias | Note=Poly-Pro |
| Hgene | AFF1 | chr4:87968752 | chr11:118359327 | ENST00000307808 | + | 3 | 20 | 871_874 | 346.0 | 1211.0 | Compositional bias | Note=Poly-Ser |
| Hgene | AFF1 | chr4:87968752 | chr11:118359327 | ENST00000395146 | + | 4 | 21 | 483_492 | 353.0 | 1219.0 | Compositional bias | Note=Poly-Ser |
| Hgene | AFF1 | chr4:87968752 | chr11:118359327 | ENST00000395146 | + | 4 | 21 | 835_843 | 353.0 | 1219.0 | Compositional bias | Note=Poly-Ser |
| Hgene | AFF1 | chr4:87968752 | chr11:118359327 | ENST00000395146 | + | 4 | 21 | 866_869 | 353.0 | 1219.0 | Compositional bias | Note=Poly-Pro |
| Hgene | AFF1 | chr4:87968752 | chr11:118359327 | ENST00000395146 | + | 4 | 21 | 871_874 | 353.0 | 1219.0 | Compositional bias | Note=Poly-Ser |
| Hgene | AFF1 | chr4:88005317 | chr11:118354896 | ENST00000307808 | + | 4 | 20 | 483_492 | 361.0 | 1211.0 | Compositional bias | Note=Poly-Ser |
| Hgene | AFF1 | chr4:88005317 | chr11:118354896 | ENST00000307808 | + | 4 | 20 | 835_843 | 361.0 | 1211.0 | Compositional bias | Note=Poly-Ser |
| Hgene | AFF1 | chr4:88005317 | chr11:118354896 | ENST00000307808 | + | 4 | 20 | 866_869 | 361.0 | 1211.0 | Compositional bias | Note=Poly-Pro |
| Hgene | AFF1 | chr4:88005317 | chr11:118354896 | ENST00000307808 | + | 4 | 20 | 871_874 | 361.0 | 1211.0 | Compositional bias | Note=Poly-Ser |
| Hgene | AFF1 | chr4:88005317 | chr11:118354896 | ENST00000395146 | + | 5 | 21 | 483_492 | 368.0 | 1219.0 | Compositional bias | Note=Poly-Ser |
| Hgene | AFF1 | chr4:88005317 | chr11:118354896 | ENST00000395146 | + | 5 | 21 | 835_843 | 368.0 | 1219.0 | Compositional bias | Note=Poly-Ser |
| Hgene | AFF1 | chr4:88005317 | chr11:118354896 | ENST00000395146 | + | 5 | 21 | 866_869 | 368.0 | 1219.0 | Compositional bias | Note=Poly-Pro |
| Hgene | AFF1 | chr4:88005317 | chr11:118354896 | ENST00000395146 | + | 5 | 21 | 871_874 | 368.0 | 1219.0 | Compositional bias | Note=Poly-Ser |
| Hgene | AFF1 | chr4:87967438 | chr11:118354897 | ENST00000307808 | 2 | 20 | 1098_1119 | 46.0 | 1211.0 | Region | Disordered | |
| Hgene | AFF1 | chr4:87967438 | chr11:118354897 | ENST00000307808 | 2 | 20 | 366_957 | 46.0 | 1211.0 | Region | Disordered | |
| Hgene | AFF1 | chr4:87967438 | chr11:118354897 | ENST00000307808 | 2 | 20 | 73_314 | 46.0 | 1211.0 | Region | Disordered | |
| Hgene | AFF1 | chr4:87967438 | chr11:118354897 | ENST00000395146 | 3 | 21 | 1098_1119 | 53.0 | 1219.0 | Region | Disordered | |
| Hgene | AFF1 | chr4:87967438 | chr11:118354897 | ENST00000395146 | 3 | 21 | 366_957 | 53.0 | 1219.0 | Region | Disordered | |
| Hgene | AFF1 | chr4:87967438 | chr11:118354897 | ENST00000395146 | 3 | 21 | 73_314 | 53.0 | 1219.0 | Region | Disordered | |
| Hgene | AFF1 | chr4:87967438 | chr11:118359328 | ENST00000307808 | 2 | 20 | 1098_1119 | 46.0 | 1211.0 | Region | Disordered | |
| Hgene | AFF1 | chr4:87967438 | chr11:118359328 | ENST00000307808 | 2 | 20 | 366_957 | 46.0 | 1211.0 | Region | Disordered | |
| Hgene | AFF1 | chr4:87967438 | chr11:118359328 | ENST00000307808 | 2 | 20 | 73_314 | 46.0 | 1211.0 | Region | Disordered | |
| Hgene | AFF1 | chr4:87967438 | chr11:118359328 | ENST00000395146 | 3 | 21 | 1098_1119 | 53.0 | 1219.0 | Region | Disordered | |
| Hgene | AFF1 | chr4:87967438 | chr11:118359328 | ENST00000395146 | 3 | 21 | 366_957 | 53.0 | 1219.0 | Region | Disordered | |
| Hgene | AFF1 | chr4:87967438 | chr11:118359328 | ENST00000395146 | 3 | 21 | 73_314 | 53.0 | 1219.0 | Region | Disordered | |
| Hgene | AFF1 | chr4:87968746 | chr11:118354897 | ENST00000307808 | 3 | 20 | 1098_1119 | 346.0 | 1211.0 | Region | Disordered | |
| Hgene | AFF1 | chr4:87968746 | chr11:118354897 | ENST00000307808 | 3 | 20 | 366_957 | 346.0 | 1211.0 | Region | Disordered | |
| Hgene | AFF1 | chr4:87968746 | chr11:118354897 | ENST00000395146 | 4 | 21 | 1098_1119 | 353.0 | 1219.0 | Region | Disordered | |
| Hgene | AFF1 | chr4:87968746 | chr11:118354897 | ENST00000395146 | 4 | 21 | 366_957 | 353.0 | 1219.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000354520 | 7 | 35 | 1046_1061 | 1362.0 | 3932.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000354520 | 7 | 35 | 1249_1272 | 1362.0 | 3932.0 | Compositional bias | Basic and acidic residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000354520 | 7 | 35 | 1278_1302 | 1362.0 | 3932.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000354520 | 7 | 35 | 1303_1317 | 1362.0 | 3932.0 | Compositional bias | Pro residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000354520 | 7 | 35 | 184_203 | 1362.0 | 3932.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000354520 | 7 | 35 | 204_226 | 1362.0 | 3932.0 | Compositional bias | Basic and acidic residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000354520 | 7 | 35 | 236_253 | 1362.0 | 3932.0 | Compositional bias | Basic and acidic residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000354520 | 7 | 35 | 325_351 | 1362.0 | 3932.0 | Compositional bias | Basic and acidic residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000354520 | 7 | 35 | 37_58 | 1362.0 | 3932.0 | Compositional bias | Pro residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000354520 | 7 | 35 | 445_495 | 1362.0 | 3932.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000354520 | 7 | 35 | 535_556 | 1362.0 | 3932.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000354520 | 7 | 35 | 557_576 | 1362.0 | 3932.0 | Compositional bias | Pro residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000354520 | 7 | 35 | 713_731 | 1362.0 | 3932.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000354520 | 7 | 35 | 747_780 | 1362.0 | 3932.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000354520 | 7 | 35 | 798_845 | 1362.0 | 3932.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000354520 | 7 | 35 | 81_103 | 1362.0 | 3932.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000354520 | 7 | 35 | 846_898 | 1362.0 | 3932.0 | Compositional bias | Basic and acidic residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000389506 | 7 | 36 | 1046_1061 | 1362.0 | 3970.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000389506 | 7 | 36 | 1249_1272 | 1362.0 | 3970.0 | Compositional bias | Basic and acidic residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000389506 | 7 | 36 | 1278_1302 | 1362.0 | 3970.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000389506 | 7 | 36 | 1303_1317 | 1362.0 | 3970.0 | Compositional bias | Pro residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000389506 | 7 | 36 | 184_203 | 1362.0 | 3970.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000389506 | 7 | 36 | 204_226 | 1362.0 | 3970.0 | Compositional bias | Basic and acidic residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000389506 | 7 | 36 | 236_253 | 1362.0 | 3970.0 | Compositional bias | Basic and acidic residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000389506 | 7 | 36 | 325_351 | 1362.0 | 3970.0 | Compositional bias | Basic and acidic residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000389506 | 7 | 36 | 37_58 | 1362.0 | 3970.0 | Compositional bias | Pro residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000389506 | 7 | 36 | 445_495 | 1362.0 | 3970.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000389506 | 7 | 36 | 535_556 | 1362.0 | 3970.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000389506 | 7 | 36 | 557_576 | 1362.0 | 3970.0 | Compositional bias | Pro residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000389506 | 7 | 36 | 713_731 | 1362.0 | 3970.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000389506 | 7 | 36 | 747_780 | 1362.0 | 3970.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000389506 | 7 | 36 | 798_845 | 1362.0 | 3970.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000389506 | 7 | 36 | 81_103 | 1362.0 | 3970.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000389506 | 7 | 36 | 846_898 | 1362.0 | 3970.0 | Compositional bias | Basic and acidic residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000534358 | 7 | 36 | 1046_1061 | 1362.0 | 3973.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000534358 | 7 | 36 | 1249_1272 | 1362.0 | 3973.0 | Compositional bias | Basic and acidic residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000534358 | 7 | 36 | 1278_1302 | 1362.0 | 3973.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000534358 | 7 | 36 | 1303_1317 | 1362.0 | 3973.0 | Compositional bias | Pro residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000534358 | 7 | 36 | 184_203 | 1362.0 | 3973.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000534358 | 7 | 36 | 204_226 | 1362.0 | 3973.0 | Compositional bias | Basic and acidic residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000534358 | 7 | 36 | 236_253 | 1362.0 | 3973.0 | Compositional bias | Basic and acidic residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000534358 | 7 | 36 | 325_351 | 1362.0 | 3973.0 | Compositional bias | Basic and acidic residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000534358 | 7 | 36 | 37_58 | 1362.0 | 3973.0 | Compositional bias | Pro residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000534358 | 7 | 36 | 445_495 | 1362.0 | 3973.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000534358 | 7 | 36 | 535_556 | 1362.0 | 3973.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000534358 | 7 | 36 | 557_576 | 1362.0 | 3973.0 | Compositional bias | Pro residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000534358 | 7 | 36 | 713_731 | 1362.0 | 3973.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000534358 | 7 | 36 | 747_780 | 1362.0 | 3973.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000534358 | 7 | 36 | 798_845 | 1362.0 | 3973.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000534358 | 7 | 36 | 81_103 | 1362.0 | 3973.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000534358 | 7 | 36 | 846_898 | 1362.0 | 3973.0 | Compositional bias | Basic and acidic residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000354520 | 8 | 35 | 1046_1061 | 1406.0 | 3932.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000354520 | 8 | 35 | 1249_1272 | 1406.0 | 3932.0 | Compositional bias | Basic and acidic residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000354520 | 8 | 35 | 1278_1302 | 1406.0 | 3932.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000354520 | 8 | 35 | 1303_1317 | 1406.0 | 3932.0 | Compositional bias | Pro residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000354520 | 8 | 35 | 184_203 | 1406.0 | 3932.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000354520 | 8 | 35 | 204_226 | 1406.0 | 3932.0 | Compositional bias | Basic and acidic residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000354520 | 8 | 35 | 236_253 | 1406.0 | 3932.0 | Compositional bias | Basic and acidic residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000354520 | 8 | 35 | 325_351 | 1406.0 | 3932.0 | Compositional bias | Basic and acidic residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000354520 | 8 | 35 | 37_58 | 1406.0 | 3932.0 | Compositional bias | Pro residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000354520 | 8 | 35 | 445_495 | 1406.0 | 3932.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000354520 | 8 | 35 | 535_556 | 1406.0 | 3932.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000354520 | 8 | 35 | 557_576 | 1406.0 | 3932.0 | Compositional bias | Pro residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000354520 | 8 | 35 | 713_731 | 1406.0 | 3932.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000354520 | 8 | 35 | 747_780 | 1406.0 | 3932.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000354520 | 8 | 35 | 798_845 | 1406.0 | 3932.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000354520 | 8 | 35 | 81_103 | 1406.0 | 3932.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000354520 | 8 | 35 | 846_898 | 1406.0 | 3932.0 | Compositional bias | Basic and acidic residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000389506 | 9 | 36 | 1046_1061 | 1444.0 | 3970.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000389506 | 9 | 36 | 1249_1272 | 1444.0 | 3970.0 | Compositional bias | Basic and acidic residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000389506 | 9 | 36 | 1278_1302 | 1444.0 | 3970.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000389506 | 9 | 36 | 1303_1317 | 1444.0 | 3970.0 | Compositional bias | Pro residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000389506 | 9 | 36 | 184_203 | 1444.0 | 3970.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000389506 | 9 | 36 | 204_226 | 1444.0 | 3970.0 | Compositional bias | Basic and acidic residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000389506 | 9 | 36 | 236_253 | 1444.0 | 3970.0 | Compositional bias | Basic and acidic residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000389506 | 9 | 36 | 325_351 | 1444.0 | 3970.0 | Compositional bias | Basic and acidic residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000389506 | 9 | 36 | 37_58 | 1444.0 | 3970.0 | Compositional bias | Pro residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000389506 | 9 | 36 | 445_495 | 1444.0 | 3970.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000389506 | 9 | 36 | 535_556 | 1444.0 | 3970.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000389506 | 9 | 36 | 557_576 | 1444.0 | 3970.0 | Compositional bias | Pro residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000389506 | 9 | 36 | 713_731 | 1444.0 | 3970.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000389506 | 9 | 36 | 747_780 | 1444.0 | 3970.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000389506 | 9 | 36 | 798_845 | 1444.0 | 3970.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000389506 | 9 | 36 | 81_103 | 1444.0 | 3970.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000389506 | 9 | 36 | 846_898 | 1444.0 | 3970.0 | Compositional bias | Basic and acidic residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000534358 | 9 | 36 | 1046_1061 | 1444.0 | 3973.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000534358 | 9 | 36 | 1249_1272 | 1444.0 | 3973.0 | Compositional bias | Basic and acidic residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000534358 | 9 | 36 | 1278_1302 | 1444.0 | 3973.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000534358 | 9 | 36 | 1303_1317 | 1444.0 | 3973.0 | Compositional bias | Pro residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000534358 | 9 | 36 | 184_203 | 1444.0 | 3973.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000534358 | 9 | 36 | 204_226 | 1444.0 | 3973.0 | Compositional bias | Basic and acidic residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000534358 | 9 | 36 | 236_253 | 1444.0 | 3973.0 | Compositional bias | Basic and acidic residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000534358 | 9 | 36 | 325_351 | 1444.0 | 3973.0 | Compositional bias | Basic and acidic residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000534358 | 9 | 36 | 37_58 | 1444.0 | 3973.0 | Compositional bias | Pro residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000534358 | 9 | 36 | 445_495 | 1444.0 | 3973.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000534358 | 9 | 36 | 535_556 | 1444.0 | 3973.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000534358 | 9 | 36 | 557_576 | 1444.0 | 3973.0 | Compositional bias | Pro residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000534358 | 9 | 36 | 713_731 | 1444.0 | 3973.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000534358 | 9 | 36 | 747_780 | 1444.0 | 3973.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000534358 | 9 | 36 | 798_845 | 1444.0 | 3973.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000534358 | 9 | 36 | 81_103 | 1444.0 | 3973.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000534358 | 9 | 36 | 846_898 | 1444.0 | 3973.0 | Compositional bias | Basic and acidic residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000354520 | 7 | 35 | 1046_1061 | 1362.0 | 3932.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000354520 | 7 | 35 | 1249_1272 | 1362.0 | 3932.0 | Compositional bias | Basic and acidic residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000354520 | 7 | 35 | 1278_1302 | 1362.0 | 3932.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000354520 | 7 | 35 | 1303_1317 | 1362.0 | 3932.0 | Compositional bias | Pro residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000354520 | 7 | 35 | 184_203 | 1362.0 | 3932.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000354520 | 7 | 35 | 204_226 | 1362.0 | 3932.0 | Compositional bias | Basic and acidic residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000354520 | 7 | 35 | 236_253 | 1362.0 | 3932.0 | Compositional bias | Basic and acidic residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000354520 | 7 | 35 | 325_351 | 1362.0 | 3932.0 | Compositional bias | Basic and acidic residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000354520 | 7 | 35 | 37_58 | 1362.0 | 3932.0 | Compositional bias | Pro residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000354520 | 7 | 35 | 445_495 | 1362.0 | 3932.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000354520 | 7 | 35 | 535_556 | 1362.0 | 3932.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000354520 | 7 | 35 | 557_576 | 1362.0 | 3932.0 | Compositional bias | Pro residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000354520 | 7 | 35 | 713_731 | 1362.0 | 3932.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000354520 | 7 | 35 | 747_780 | 1362.0 | 3932.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000354520 | 7 | 35 | 798_845 | 1362.0 | 3932.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000354520 | 7 | 35 | 81_103 | 1362.0 | 3932.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000354520 | 7 | 35 | 846_898 | 1362.0 | 3932.0 | Compositional bias | Basic and acidic residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000389506 | 7 | 36 | 1046_1061 | 1362.0 | 3970.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000389506 | 7 | 36 | 1249_1272 | 1362.0 | 3970.0 | Compositional bias | Basic and acidic residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000389506 | 7 | 36 | 1278_1302 | 1362.0 | 3970.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000389506 | 7 | 36 | 1303_1317 | 1362.0 | 3970.0 | Compositional bias | Pro residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000389506 | 7 | 36 | 184_203 | 1362.0 | 3970.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000389506 | 7 | 36 | 204_226 | 1362.0 | 3970.0 | Compositional bias | Basic and acidic residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000389506 | 7 | 36 | 236_253 | 1362.0 | 3970.0 | Compositional bias | Basic and acidic residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000389506 | 7 | 36 | 325_351 | 1362.0 | 3970.0 | Compositional bias | Basic and acidic residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000389506 | 7 | 36 | 37_58 | 1362.0 | 3970.0 | Compositional bias | Pro residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000389506 | 7 | 36 | 445_495 | 1362.0 | 3970.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000389506 | 7 | 36 | 535_556 | 1362.0 | 3970.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000389506 | 7 | 36 | 557_576 | 1362.0 | 3970.0 | Compositional bias | Pro residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000389506 | 7 | 36 | 713_731 | 1362.0 | 3970.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000389506 | 7 | 36 | 747_780 | 1362.0 | 3970.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000389506 | 7 | 36 | 798_845 | 1362.0 | 3970.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000389506 | 7 | 36 | 81_103 | 1362.0 | 3970.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000389506 | 7 | 36 | 846_898 | 1362.0 | 3970.0 | Compositional bias | Basic and acidic residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000534358 | 7 | 36 | 1046_1061 | 1362.0 | 3973.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000534358 | 7 | 36 | 1249_1272 | 1362.0 | 3973.0 | Compositional bias | Basic and acidic residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000534358 | 7 | 36 | 1278_1302 | 1362.0 | 3973.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000534358 | 7 | 36 | 1303_1317 | 1362.0 | 3973.0 | Compositional bias | Pro residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000534358 | 7 | 36 | 184_203 | 1362.0 | 3973.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000534358 | 7 | 36 | 204_226 | 1362.0 | 3973.0 | Compositional bias | Basic and acidic residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000534358 | 7 | 36 | 236_253 | 1362.0 | 3973.0 | Compositional bias | Basic and acidic residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000534358 | 7 | 36 | 325_351 | 1362.0 | 3973.0 | Compositional bias | Basic and acidic residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000534358 | 7 | 36 | 37_58 | 1362.0 | 3973.0 | Compositional bias | Pro residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000534358 | 7 | 36 | 445_495 | 1362.0 | 3973.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000534358 | 7 | 36 | 535_556 | 1362.0 | 3973.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000534358 | 7 | 36 | 557_576 | 1362.0 | 3973.0 | Compositional bias | Pro residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000534358 | 7 | 36 | 713_731 | 1362.0 | 3973.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000534358 | 7 | 36 | 747_780 | 1362.0 | 3973.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000534358 | 7 | 36 | 798_845 | 1362.0 | 3973.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000534358 | 7 | 36 | 81_103 | 1362.0 | 3973.0 | Compositional bias | Polar residues | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000534358 | 7 | 36 | 846_898 | 1362.0 | 3973.0 | Compositional bias | Basic and acidic residues | |
| Tgene | KMT2A | chr4:87968747 | chr11:118354896 | ENST00000354520 | 7 | 35 | 137_143 | 1362.0 | 3932.0 | Compositional bias | Note=Poly-Gly | |
| Tgene | KMT2A | chr4:87968747 | chr11:118354896 | ENST00000354520 | 7 | 35 | 17_102 | 1362.0 | 3932.0 | Compositional bias | Note=Ala/Gly/Ser-rich | |
| Tgene | KMT2A | chr4:87968747 | chr11:118354896 | ENST00000354520 | 7 | 35 | 561_564 | 1362.0 | 3932.0 | Compositional bias | Note=Poly-Pro | |
| Tgene | KMT2A | chr4:87968747 | chr11:118354896 | ENST00000354520 | 7 | 35 | 568_571 | 1362.0 | 3932.0 | Compositional bias | Note=Poly-Pro | |
| Tgene | KMT2A | chr4:87968747 | chr11:118354896 | ENST00000389506 | 7 | 36 | 137_143 | 1362.0 | 3970.0 | Compositional bias | Note=Poly-Gly | |
| Tgene | KMT2A | chr4:87968747 | chr11:118354896 | ENST00000389506 | 7 | 36 | 17_102 | 1362.0 | 3970.0 | Compositional bias | Note=Ala/Gly/Ser-rich | |
| Tgene | KMT2A | chr4:87968747 | chr11:118354896 | ENST00000389506 | 7 | 36 | 561_564 | 1362.0 | 3970.0 | Compositional bias | Note=Poly-Pro | |
| Tgene | KMT2A | chr4:87968747 | chr11:118354896 | ENST00000389506 | 7 | 36 | 568_571 | 1362.0 | 3970.0 | Compositional bias | Note=Poly-Pro | |
| Tgene | KMT2A | chr4:87968747 | chr11:118354896 | ENST00000534358 | 7 | 36 | 137_143 | 1362.0 | 3973.0 | Compositional bias | Note=Poly-Gly | |
| Tgene | KMT2A | chr4:87968747 | chr11:118354896 | ENST00000534358 | 7 | 36 | 17_102 | 1362.0 | 3973.0 | Compositional bias | Note=Ala/Gly/Ser-rich | |
| Tgene | KMT2A | chr4:87968747 | chr11:118354896 | ENST00000534358 | 7 | 36 | 561_564 | 1362.0 | 3973.0 | Compositional bias | Note=Poly-Pro | |
| Tgene | KMT2A | chr4:87968747 | chr11:118354896 | ENST00000534358 | 7 | 36 | 568_571 | 1362.0 | 3973.0 | Compositional bias | Note=Poly-Pro | |
| Tgene | KMT2A | chr4:87968752 | chr11:118359327 | ENST00000354520 | 8 | 35 | 137_143 | 1406.0 | 3932.0 | Compositional bias | Note=Poly-Gly | |
| Tgene | KMT2A | chr4:87968752 | chr11:118359327 | ENST00000354520 | 8 | 35 | 17_102 | 1406.0 | 3932.0 | Compositional bias | Note=Ala/Gly/Ser-rich | |
| Tgene | KMT2A | chr4:87968752 | chr11:118359327 | ENST00000354520 | 8 | 35 | 561_564 | 1406.0 | 3932.0 | Compositional bias | Note=Poly-Pro | |
| Tgene | KMT2A | chr4:87968752 | chr11:118359327 | ENST00000354520 | 8 | 35 | 568_571 | 1406.0 | 3932.0 | Compositional bias | Note=Poly-Pro | |
| Tgene | KMT2A | chr4:87968752 | chr11:118359327 | ENST00000389506 | 9 | 36 | 137_143 | 1444.0 | 3970.0 | Compositional bias | Note=Poly-Gly | |
| Tgene | KMT2A | chr4:87968752 | chr11:118359327 | ENST00000389506 | 9 | 36 | 17_102 | 1444.0 | 3970.0 | Compositional bias | Note=Ala/Gly/Ser-rich | |
| Tgene | KMT2A | chr4:87968752 | chr11:118359327 | ENST00000389506 | 9 | 36 | 561_564 | 1444.0 | 3970.0 | Compositional bias | Note=Poly-Pro | |
| Tgene | KMT2A | chr4:87968752 | chr11:118359327 | ENST00000389506 | 9 | 36 | 568_571 | 1444.0 | 3970.0 | Compositional bias | Note=Poly-Pro | |
| Tgene | KMT2A | chr4:87968752 | chr11:118359327 | ENST00000534358 | 9 | 36 | 137_143 | 1444.0 | 3973.0 | Compositional bias | Note=Poly-Gly | |
| Tgene | KMT2A | chr4:87968752 | chr11:118359327 | ENST00000534358 | 9 | 36 | 17_102 | 1444.0 | 3973.0 | Compositional bias | Note=Ala/Gly/Ser-rich | |
| Tgene | KMT2A | chr4:87968752 | chr11:118359327 | ENST00000534358 | 9 | 36 | 561_564 | 1444.0 | 3973.0 | Compositional bias | Note=Poly-Pro | |
| Tgene | KMT2A | chr4:87968752 | chr11:118359327 | ENST00000534358 | 9 | 36 | 568_571 | 1444.0 | 3973.0 | Compositional bias | Note=Poly-Pro | |
| Tgene | KMT2A | chr4:88005317 | chr11:118354896 | ENST00000354520 | 7 | 35 | 137_143 | 1362.0 | 3932.0 | Compositional bias | Note=Poly-Gly | |
| Tgene | KMT2A | chr4:88005317 | chr11:118354896 | ENST00000354520 | 7 | 35 | 17_102 | 1362.0 | 3932.0 | Compositional bias | Note=Ala/Gly/Ser-rich | |
| Tgene | KMT2A | chr4:88005317 | chr11:118354896 | ENST00000354520 | 7 | 35 | 561_564 | 1362.0 | 3932.0 | Compositional bias | Note=Poly-Pro | |
| Tgene | KMT2A | chr4:88005317 | chr11:118354896 | ENST00000354520 | 7 | 35 | 568_571 | 1362.0 | 3932.0 | Compositional bias | Note=Poly-Pro | |
| Tgene | KMT2A | chr4:88005317 | chr11:118354896 | ENST00000389506 | 7 | 36 | 137_143 | 1362.0 | 3970.0 | Compositional bias | Note=Poly-Gly | |
| Tgene | KMT2A | chr4:88005317 | chr11:118354896 | ENST00000389506 | 7 | 36 | 17_102 | 1362.0 | 3970.0 | Compositional bias | Note=Ala/Gly/Ser-rich | |
| Tgene | KMT2A | chr4:88005317 | chr11:118354896 | ENST00000389506 | 7 | 36 | 561_564 | 1362.0 | 3970.0 | Compositional bias | Note=Poly-Pro | |
| Tgene | KMT2A | chr4:88005317 | chr11:118354896 | ENST00000389506 | 7 | 36 | 568_571 | 1362.0 | 3970.0 | Compositional bias | Note=Poly-Pro | |
| Tgene | KMT2A | chr4:88005317 | chr11:118354896 | ENST00000534358 | 7 | 36 | 137_143 | 1362.0 | 3973.0 | Compositional bias | Note=Poly-Gly | |
| Tgene | KMT2A | chr4:88005317 | chr11:118354896 | ENST00000534358 | 7 | 36 | 17_102 | 1362.0 | 3973.0 | Compositional bias | Note=Ala/Gly/Ser-rich | |
| Tgene | KMT2A | chr4:88005317 | chr11:118354896 | ENST00000534358 | 7 | 36 | 561_564 | 1362.0 | 3973.0 | Compositional bias | Note=Poly-Pro | |
| Tgene | KMT2A | chr4:88005317 | chr11:118354896 | ENST00000534358 | 7 | 36 | 568_571 | 1362.0 | 3973.0 | Compositional bias | Note=Poly-Pro | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000354520 | 7 | 35 | 169_180 | 1362.0 | 3932.0 | DNA binding | Note=A.T hook 1 | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000354520 | 7 | 35 | 217_227 | 1362.0 | 3932.0 | DNA binding | Note=A.T hook 2 | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000354520 | 7 | 35 | 301_309 | 1362.0 | 3932.0 | DNA binding | Note=A.T hook 3 | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000389506 | 7 | 36 | 169_180 | 1362.0 | 3970.0 | DNA binding | Note=A.T hook 1 | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000389506 | 7 | 36 | 217_227 | 1362.0 | 3970.0 | DNA binding | Note=A.T hook 2 | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000389506 | 7 | 36 | 301_309 | 1362.0 | 3970.0 | DNA binding | Note=A.T hook 3 | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000534358 | 7 | 36 | 169_180 | 1362.0 | 3973.0 | DNA binding | Note=A.T hook 1 | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000534358 | 7 | 36 | 217_227 | 1362.0 | 3973.0 | DNA binding | Note=A.T hook 2 | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000534358 | 7 | 36 | 301_309 | 1362.0 | 3973.0 | DNA binding | Note=A.T hook 3 | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000354520 | 8 | 35 | 169_180 | 1406.0 | 3932.0 | DNA binding | Note=A.T hook 1 | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000354520 | 8 | 35 | 217_227 | 1406.0 | 3932.0 | DNA binding | Note=A.T hook 2 | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000354520 | 8 | 35 | 301_309 | 1406.0 | 3932.0 | DNA binding | Note=A.T hook 3 | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000389506 | 9 | 36 | 169_180 | 1444.0 | 3970.0 | DNA binding | Note=A.T hook 1 | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000389506 | 9 | 36 | 217_227 | 1444.0 | 3970.0 | DNA binding | Note=A.T hook 2 | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000389506 | 9 | 36 | 301_309 | 1444.0 | 3970.0 | DNA binding | Note=A.T hook 3 | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000534358 | 9 | 36 | 169_180 | 1444.0 | 3973.0 | DNA binding | Note=A.T hook 1 | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000534358 | 9 | 36 | 217_227 | 1444.0 | 3973.0 | DNA binding | Note=A.T hook 2 | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000534358 | 9 | 36 | 301_309 | 1444.0 | 3973.0 | DNA binding | Note=A.T hook 3 | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000354520 | 7 | 35 | 169_180 | 1362.0 | 3932.0 | DNA binding | Note=A.T hook 1 | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000354520 | 7 | 35 | 217_227 | 1362.0 | 3932.0 | DNA binding | Note=A.T hook 2 | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000354520 | 7 | 35 | 301_309 | 1362.0 | 3932.0 | DNA binding | Note=A.T hook 3 | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000389506 | 7 | 36 | 169_180 | 1362.0 | 3970.0 | DNA binding | Note=A.T hook 1 | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000389506 | 7 | 36 | 217_227 | 1362.0 | 3970.0 | DNA binding | Note=A.T hook 2 | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000389506 | 7 | 36 | 301_309 | 1362.0 | 3970.0 | DNA binding | Note=A.T hook 3 | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000534358 | 7 | 36 | 169_180 | 1362.0 | 3973.0 | DNA binding | Note=A.T hook 1 | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000534358 | 7 | 36 | 217_227 | 1362.0 | 3973.0 | DNA binding | Note=A.T hook 2 | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000534358 | 7 | 36 | 301_309 | 1362.0 | 3973.0 | DNA binding | Note=A.T hook 3 | |
| Tgene | KMT2A | chr4:87968747 | chr11:118354896 | ENST00000354520 | 7 | 35 | 169_180 | 1362.0 | 3932.0 | DNA binding | Note=A.T hook 1 | |
| Tgene | KMT2A | chr4:87968747 | chr11:118354896 | ENST00000354520 | 7 | 35 | 217_227 | 1362.0 | 3932.0 | DNA binding | Note=A.T hook 2 | |
| Tgene | KMT2A | chr4:87968747 | chr11:118354896 | ENST00000354520 | 7 | 35 | 301_309 | 1362.0 | 3932.0 | DNA binding | Note=A.T hook 3 | |
| Tgene | KMT2A | chr4:87968747 | chr11:118354896 | ENST00000389506 | 7 | 36 | 169_180 | 1362.0 | 3970.0 | DNA binding | Note=A.T hook 1 | |
| Tgene | KMT2A | chr4:87968747 | chr11:118354896 | ENST00000389506 | 7 | 36 | 217_227 | 1362.0 | 3970.0 | DNA binding | Note=A.T hook 2 | |
| Tgene | KMT2A | chr4:87968747 | chr11:118354896 | ENST00000389506 | 7 | 36 | 301_309 | 1362.0 | 3970.0 | DNA binding | Note=A.T hook 3 | |
| Tgene | KMT2A | chr4:87968747 | chr11:118354896 | ENST00000534358 | 7 | 36 | 169_180 | 1362.0 | 3973.0 | DNA binding | Note=A.T hook 1 | |
| Tgene | KMT2A | chr4:87968747 | chr11:118354896 | ENST00000534358 | 7 | 36 | 217_227 | 1362.0 | 3973.0 | DNA binding | Note=A.T hook 2 | |
| Tgene | KMT2A | chr4:87968747 | chr11:118354896 | ENST00000534358 | 7 | 36 | 301_309 | 1362.0 | 3973.0 | DNA binding | Note=A.T hook 3 | |
| Tgene | KMT2A | chr4:87968752 | chr11:118359327 | ENST00000354520 | 8 | 35 | 169_180 | 1406.0 | 3932.0 | DNA binding | Note=A.T hook 1 | |
| Tgene | KMT2A | chr4:87968752 | chr11:118359327 | ENST00000354520 | 8 | 35 | 217_227 | 1406.0 | 3932.0 | DNA binding | Note=A.T hook 2 | |
| Tgene | KMT2A | chr4:87968752 | chr11:118359327 | ENST00000354520 | 8 | 35 | 301_309 | 1406.0 | 3932.0 | DNA binding | Note=A.T hook 3 | |
| Tgene | KMT2A | chr4:87968752 | chr11:118359327 | ENST00000389506 | 9 | 36 | 169_180 | 1444.0 | 3970.0 | DNA binding | Note=A.T hook 1 | |
| Tgene | KMT2A | chr4:87968752 | chr11:118359327 | ENST00000389506 | 9 | 36 | 217_227 | 1444.0 | 3970.0 | DNA binding | Note=A.T hook 2 | |
| Tgene | KMT2A | chr4:87968752 | chr11:118359327 | ENST00000389506 | 9 | 36 | 301_309 | 1444.0 | 3970.0 | DNA binding | Note=A.T hook 3 | |
| Tgene | KMT2A | chr4:87968752 | chr11:118359327 | ENST00000534358 | 9 | 36 | 169_180 | 1444.0 | 3973.0 | DNA binding | Note=A.T hook 1 | |
| Tgene | KMT2A | chr4:87968752 | chr11:118359327 | ENST00000534358 | 9 | 36 | 217_227 | 1444.0 | 3973.0 | DNA binding | Note=A.T hook 2 | |
| Tgene | KMT2A | chr4:87968752 | chr11:118359327 | ENST00000534358 | 9 | 36 | 301_309 | 1444.0 | 3973.0 | DNA binding | Note=A.T hook 3 | |
| Tgene | KMT2A | chr4:88005317 | chr11:118354896 | ENST00000354520 | 7 | 35 | 169_180 | 1362.0 | 3932.0 | DNA binding | Note=A.T hook 1 | |
| Tgene | KMT2A | chr4:88005317 | chr11:118354896 | ENST00000354520 | 7 | 35 | 217_227 | 1362.0 | 3932.0 | DNA binding | Note=A.T hook 2 | |
| Tgene | KMT2A | chr4:88005317 | chr11:118354896 | ENST00000354520 | 7 | 35 | 301_309 | 1362.0 | 3932.0 | DNA binding | Note=A.T hook 3 | |
| Tgene | KMT2A | chr4:88005317 | chr11:118354896 | ENST00000389506 | 7 | 36 | 169_180 | 1362.0 | 3970.0 | DNA binding | Note=A.T hook 1 | |
| Tgene | KMT2A | chr4:88005317 | chr11:118354896 | ENST00000389506 | 7 | 36 | 217_227 | 1362.0 | 3970.0 | DNA binding | Note=A.T hook 2 | |
| Tgene | KMT2A | chr4:88005317 | chr11:118354896 | ENST00000389506 | 7 | 36 | 301_309 | 1362.0 | 3970.0 | DNA binding | Note=A.T hook 3 | |
| Tgene | KMT2A | chr4:88005317 | chr11:118354896 | ENST00000534358 | 7 | 36 | 169_180 | 1362.0 | 3973.0 | DNA binding | Note=A.T hook 1 | |
| Tgene | KMT2A | chr4:88005317 | chr11:118354896 | ENST00000534358 | 7 | 36 | 217_227 | 1362.0 | 3973.0 | DNA binding | Note=A.T hook 2 | |
| Tgene | KMT2A | chr4:88005317 | chr11:118354896 | ENST00000534358 | 7 | 36 | 301_309 | 1362.0 | 3973.0 | DNA binding | Note=A.T hook 3 | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000354520 | 7 | 35 | 123_134 | 1362.0 | 3932.0 | Motif | Integrase domain-binding motif 1 (IBM1) | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000354520 | 7 | 35 | 147_152 | 1362.0 | 3932.0 | Motif | Integrase domain-binding motif 2 (IBM2) | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000354520 | 7 | 35 | 6_25 | 1362.0 | 3932.0 | Motif | Menin-binding motif (MBM) | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000389506 | 7 | 36 | 123_134 | 1362.0 | 3970.0 | Motif | Integrase domain-binding motif 1 (IBM1) | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000389506 | 7 | 36 | 147_152 | 1362.0 | 3970.0 | Motif | Integrase domain-binding motif 2 (IBM2) | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000389506 | 7 | 36 | 6_25 | 1362.0 | 3970.0 | Motif | Menin-binding motif (MBM) | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000534358 | 7 | 36 | 123_134 | 1362.0 | 3973.0 | Motif | Integrase domain-binding motif 1 (IBM1) | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000534358 | 7 | 36 | 147_152 | 1362.0 | 3973.0 | Motif | Integrase domain-binding motif 2 (IBM2) | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000534358 | 7 | 36 | 6_25 | 1362.0 | 3973.0 | Motif | Menin-binding motif (MBM) | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000354520 | 8 | 35 | 123_134 | 1406.0 | 3932.0 | Motif | Integrase domain-binding motif 1 (IBM1) | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000354520 | 8 | 35 | 147_152 | 1406.0 | 3932.0 | Motif | Integrase domain-binding motif 2 (IBM2) | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000354520 | 8 | 35 | 6_25 | 1406.0 | 3932.0 | Motif | Menin-binding motif (MBM) | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000389506 | 9 | 36 | 123_134 | 1444.0 | 3970.0 | Motif | Integrase domain-binding motif 1 (IBM1) | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000389506 | 9 | 36 | 147_152 | 1444.0 | 3970.0 | Motif | Integrase domain-binding motif 2 (IBM2) | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000389506 | 9 | 36 | 6_25 | 1444.0 | 3970.0 | Motif | Menin-binding motif (MBM) | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000534358 | 9 | 36 | 123_134 | 1444.0 | 3973.0 | Motif | Integrase domain-binding motif 1 (IBM1) | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000534358 | 9 | 36 | 147_152 | 1444.0 | 3973.0 | Motif | Integrase domain-binding motif 2 (IBM2) | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000534358 | 9 | 36 | 6_25 | 1444.0 | 3973.0 | Motif | Menin-binding motif (MBM) | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000354520 | 7 | 35 | 123_134 | 1362.0 | 3932.0 | Motif | Integrase domain-binding motif 1 (IBM1) | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000354520 | 7 | 35 | 147_152 | 1362.0 | 3932.0 | Motif | Integrase domain-binding motif 2 (IBM2) | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000354520 | 7 | 35 | 6_25 | 1362.0 | 3932.0 | Motif | Menin-binding motif (MBM) | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000389506 | 7 | 36 | 123_134 | 1362.0 | 3970.0 | Motif | Integrase domain-binding motif 1 (IBM1) | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000389506 | 7 | 36 | 147_152 | 1362.0 | 3970.0 | Motif | Integrase domain-binding motif 2 (IBM2) | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000389506 | 7 | 36 | 6_25 | 1362.0 | 3970.0 | Motif | Menin-binding motif (MBM) | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000534358 | 7 | 36 | 123_134 | 1362.0 | 3973.0 | Motif | Integrase domain-binding motif 1 (IBM1) | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000534358 | 7 | 36 | 147_152 | 1362.0 | 3973.0 | Motif | Integrase domain-binding motif 2 (IBM2) | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000534358 | 7 | 36 | 6_25 | 1362.0 | 3973.0 | Motif | Menin-binding motif (MBM) | |
| Tgene | KMT2A | chr4:87968747 | chr11:118354896 | ENST00000354520 | 7 | 35 | 123_134 | 1362.0 | 3932.0 | Motif | Integrase domain-binding motif 1 (IBM1) | |
| Tgene | KMT2A | chr4:87968747 | chr11:118354896 | ENST00000354520 | 7 | 35 | 147_152 | 1362.0 | 3932.0 | Motif | Integrase domain-binding motif 2 (IBM2) | |
| Tgene | KMT2A | chr4:87968747 | chr11:118354896 | ENST00000354520 | 7 | 35 | 6_25 | 1362.0 | 3932.0 | Motif | Menin-binding motif (MBM) | |
| Tgene | KMT2A | chr4:87968747 | chr11:118354896 | ENST00000389506 | 7 | 36 | 123_134 | 1362.0 | 3970.0 | Motif | Integrase domain-binding motif 1 (IBM1) | |
| Tgene | KMT2A | chr4:87968747 | chr11:118354896 | ENST00000389506 | 7 | 36 | 147_152 | 1362.0 | 3970.0 | Motif | Integrase domain-binding motif 2 (IBM2) | |
| Tgene | KMT2A | chr4:87968747 | chr11:118354896 | ENST00000389506 | 7 | 36 | 6_25 | 1362.0 | 3970.0 | Motif | Menin-binding motif (MBM) | |
| Tgene | KMT2A | chr4:87968747 | chr11:118354896 | ENST00000534358 | 7 | 36 | 123_134 | 1362.0 | 3973.0 | Motif | Integrase domain-binding motif 1 (IBM1) | |
| Tgene | KMT2A | chr4:87968747 | chr11:118354896 | ENST00000534358 | 7 | 36 | 147_152 | 1362.0 | 3973.0 | Motif | Integrase domain-binding motif 2 (IBM2) | |
| Tgene | KMT2A | chr4:87968747 | chr11:118354896 | ENST00000534358 | 7 | 36 | 6_25 | 1362.0 | 3973.0 | Motif | Menin-binding motif (MBM) | |
| Tgene | KMT2A | chr4:87968752 | chr11:118359327 | ENST00000354520 | 8 | 35 | 123_134 | 1406.0 | 3932.0 | Motif | Integrase domain-binding motif 1 (IBM1) | |
| Tgene | KMT2A | chr4:87968752 | chr11:118359327 | ENST00000354520 | 8 | 35 | 147_152 | 1406.0 | 3932.0 | Motif | Integrase domain-binding motif 2 (IBM2) | |
| Tgene | KMT2A | chr4:87968752 | chr11:118359327 | ENST00000354520 | 8 | 35 | 6_25 | 1406.0 | 3932.0 | Motif | Menin-binding motif (MBM) | |
| Tgene | KMT2A | chr4:87968752 | chr11:118359327 | ENST00000389506 | 9 | 36 | 123_134 | 1444.0 | 3970.0 | Motif | Integrase domain-binding motif 1 (IBM1) | |
| Tgene | KMT2A | chr4:87968752 | chr11:118359327 | ENST00000389506 | 9 | 36 | 147_152 | 1444.0 | 3970.0 | Motif | Integrase domain-binding motif 2 (IBM2) | |
| Tgene | KMT2A | chr4:87968752 | chr11:118359327 | ENST00000389506 | 9 | 36 | 6_25 | 1444.0 | 3970.0 | Motif | Menin-binding motif (MBM) | |
| Tgene | KMT2A | chr4:87968752 | chr11:118359327 | ENST00000534358 | 9 | 36 | 123_134 | 1444.0 | 3973.0 | Motif | Integrase domain-binding motif 1 (IBM1) | |
| Tgene | KMT2A | chr4:87968752 | chr11:118359327 | ENST00000534358 | 9 | 36 | 147_152 | 1444.0 | 3973.0 | Motif | Integrase domain-binding motif 2 (IBM2) | |
| Tgene | KMT2A | chr4:87968752 | chr11:118359327 | ENST00000534358 | 9 | 36 | 6_25 | 1444.0 | 3973.0 | Motif | Menin-binding motif (MBM) | |
| Tgene | KMT2A | chr4:88005317 | chr11:118354896 | ENST00000354520 | 7 | 35 | 123_134 | 1362.0 | 3932.0 | Motif | Integrase domain-binding motif 1 (IBM1) | |
| Tgene | KMT2A | chr4:88005317 | chr11:118354896 | ENST00000354520 | 7 | 35 | 147_152 | 1362.0 | 3932.0 | Motif | Integrase domain-binding motif 2 (IBM2) | |
| Tgene | KMT2A | chr4:88005317 | chr11:118354896 | ENST00000354520 | 7 | 35 | 6_25 | 1362.0 | 3932.0 | Motif | Menin-binding motif (MBM) | |
| Tgene | KMT2A | chr4:88005317 | chr11:118354896 | ENST00000389506 | 7 | 36 | 123_134 | 1362.0 | 3970.0 | Motif | Integrase domain-binding motif 1 (IBM1) | |
| Tgene | KMT2A | chr4:88005317 | chr11:118354896 | ENST00000389506 | 7 | 36 | 147_152 | 1362.0 | 3970.0 | Motif | Integrase domain-binding motif 2 (IBM2) | |
| Tgene | KMT2A | chr4:88005317 | chr11:118354896 | ENST00000389506 | 7 | 36 | 6_25 | 1362.0 | 3970.0 | Motif | Menin-binding motif (MBM) | |
| Tgene | KMT2A | chr4:88005317 | chr11:118354896 | ENST00000534358 | 7 | 36 | 123_134 | 1362.0 | 3973.0 | Motif | Integrase domain-binding motif 1 (IBM1) | |
| Tgene | KMT2A | chr4:88005317 | chr11:118354896 | ENST00000534358 | 7 | 36 | 147_152 | 1362.0 | 3973.0 | Motif | Integrase domain-binding motif 2 (IBM2) | |
| Tgene | KMT2A | chr4:88005317 | chr11:118354896 | ENST00000534358 | 7 | 36 | 6_25 | 1362.0 | 3973.0 | Motif | Menin-binding motif (MBM) | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000354520 | 7 | 35 | 1038_1066 | 1362.0 | 3932.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000354520 | 7 | 35 | 1106_1166 | 1362.0 | 3932.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000354520 | 7 | 35 | 1200_1375 | 1362.0 | 3932.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000354520 | 7 | 35 | 132_253 | 1362.0 | 3932.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000354520 | 7 | 35 | 1_108 | 1362.0 | 3932.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000354520 | 7 | 35 | 301_352 | 1362.0 | 3932.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000354520 | 7 | 35 | 445_585 | 1362.0 | 3932.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000354520 | 7 | 35 | 713_780 | 1362.0 | 3932.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000354520 | 7 | 35 | 798_949 | 1362.0 | 3932.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000389506 | 7 | 36 | 1038_1066 | 1362.0 | 3970.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000389506 | 7 | 36 | 1106_1166 | 1362.0 | 3970.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000389506 | 7 | 36 | 1200_1375 | 1362.0 | 3970.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000389506 | 7 | 36 | 132_253 | 1362.0 | 3970.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000389506 | 7 | 36 | 1_108 | 1362.0 | 3970.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000389506 | 7 | 36 | 301_352 | 1362.0 | 3970.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000389506 | 7 | 36 | 445_585 | 1362.0 | 3970.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000389506 | 7 | 36 | 713_780 | 1362.0 | 3970.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000389506 | 7 | 36 | 798_949 | 1362.0 | 3970.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000534358 | 7 | 36 | 1038_1066 | 1362.0 | 3973.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000534358 | 7 | 36 | 1106_1166 | 1362.0 | 3973.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000534358 | 7 | 36 | 1200_1375 | 1362.0 | 3973.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000534358 | 7 | 36 | 132_253 | 1362.0 | 3973.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000534358 | 7 | 36 | 1_108 | 1362.0 | 3973.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000534358 | 7 | 36 | 301_352 | 1362.0 | 3973.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000534358 | 7 | 36 | 445_585 | 1362.0 | 3973.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000534358 | 7 | 36 | 713_780 | 1362.0 | 3973.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000534358 | 7 | 36 | 798_949 | 1362.0 | 3973.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000354520 | 8 | 35 | 1038_1066 | 1406.0 | 3932.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000354520 | 8 | 35 | 1106_1166 | 1406.0 | 3932.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000354520 | 8 | 35 | 1200_1375 | 1406.0 | 3932.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000354520 | 8 | 35 | 132_253 | 1406.0 | 3932.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000354520 | 8 | 35 | 1_108 | 1406.0 | 3932.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000354520 | 8 | 35 | 301_352 | 1406.0 | 3932.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000354520 | 8 | 35 | 445_585 | 1406.0 | 3932.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000354520 | 8 | 35 | 713_780 | 1406.0 | 3932.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000354520 | 8 | 35 | 798_949 | 1406.0 | 3932.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000389506 | 9 | 36 | 1038_1066 | 1444.0 | 3970.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000389506 | 9 | 36 | 1106_1166 | 1444.0 | 3970.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000389506 | 9 | 36 | 1200_1375 | 1444.0 | 3970.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000389506 | 9 | 36 | 132_253 | 1444.0 | 3970.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000389506 | 9 | 36 | 1_108 | 1444.0 | 3970.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000389506 | 9 | 36 | 301_352 | 1444.0 | 3970.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000389506 | 9 | 36 | 445_585 | 1444.0 | 3970.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000389506 | 9 | 36 | 713_780 | 1444.0 | 3970.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000389506 | 9 | 36 | 798_949 | 1444.0 | 3970.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000534358 | 9 | 36 | 1038_1066 | 1444.0 | 3973.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000534358 | 9 | 36 | 1106_1166 | 1444.0 | 3973.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000534358 | 9 | 36 | 1200_1375 | 1444.0 | 3973.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000534358 | 9 | 36 | 132_253 | 1444.0 | 3973.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000534358 | 9 | 36 | 1_108 | 1444.0 | 3973.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000534358 | 9 | 36 | 301_352 | 1444.0 | 3973.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000534358 | 9 | 36 | 445_585 | 1444.0 | 3973.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000534358 | 9 | 36 | 713_780 | 1444.0 | 3973.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000534358 | 9 | 36 | 798_949 | 1444.0 | 3973.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000354520 | 7 | 35 | 1038_1066 | 1362.0 | 3932.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000354520 | 7 | 35 | 1106_1166 | 1362.0 | 3932.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000354520 | 7 | 35 | 1200_1375 | 1362.0 | 3932.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000354520 | 7 | 35 | 132_253 | 1362.0 | 3932.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000354520 | 7 | 35 | 1_108 | 1362.0 | 3932.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000354520 | 7 | 35 | 301_352 | 1362.0 | 3932.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000354520 | 7 | 35 | 445_585 | 1362.0 | 3932.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000354520 | 7 | 35 | 713_780 | 1362.0 | 3932.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000354520 | 7 | 35 | 798_949 | 1362.0 | 3932.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000389506 | 7 | 36 | 1038_1066 | 1362.0 | 3970.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000389506 | 7 | 36 | 1106_1166 | 1362.0 | 3970.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000389506 | 7 | 36 | 1200_1375 | 1362.0 | 3970.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000389506 | 7 | 36 | 132_253 | 1362.0 | 3970.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000389506 | 7 | 36 | 1_108 | 1362.0 | 3970.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000389506 | 7 | 36 | 301_352 | 1362.0 | 3970.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000389506 | 7 | 36 | 445_585 | 1362.0 | 3970.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000389506 | 7 | 36 | 713_780 | 1362.0 | 3970.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000389506 | 7 | 36 | 798_949 | 1362.0 | 3970.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000534358 | 7 | 36 | 1038_1066 | 1362.0 | 3973.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000534358 | 7 | 36 | 1106_1166 | 1362.0 | 3973.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000534358 | 7 | 36 | 1200_1375 | 1362.0 | 3973.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000534358 | 7 | 36 | 132_253 | 1362.0 | 3973.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000534358 | 7 | 36 | 1_108 | 1362.0 | 3973.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000534358 | 7 | 36 | 301_352 | 1362.0 | 3973.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000534358 | 7 | 36 | 445_585 | 1362.0 | 3973.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000534358 | 7 | 36 | 713_780 | 1362.0 | 3973.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000534358 | 7 | 36 | 798_949 | 1362.0 | 3973.0 | Region | Disordered | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000354520 | 7 | 35 | 1147_1195 | 1362.0 | 3932.0 | Zinc finger | CXXC-type | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000389506 | 7 | 36 | 1147_1195 | 1362.0 | 3970.0 | Zinc finger | CXXC-type | |
| Tgene | KMT2A | chr4:87967438 | chr11:118354897 | ENST00000534358 | 7 | 36 | 1147_1195 | 1362.0 | 3973.0 | Zinc finger | CXXC-type | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000354520 | 8 | 35 | 1147_1195 | 1406.0 | 3932.0 | Zinc finger | CXXC-type | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000389506 | 9 | 36 | 1147_1195 | 1444.0 | 3970.0 | Zinc finger | CXXC-type | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000389506 | 9 | 36 | 1431_1482 | 1444.0 | 3970.0 | Zinc finger | PHD-type 1 | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000534358 | 9 | 36 | 1147_1195 | 1444.0 | 3973.0 | Zinc finger | CXXC-type | |
| Tgene | KMT2A | chr4:87967438 | chr11:118359328 | ENST00000534358 | 9 | 36 | 1431_1482 | 1444.0 | 3973.0 | Zinc finger | PHD-type 1 | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000354520 | 7 | 35 | 1147_1195 | 1362.0 | 3932.0 | Zinc finger | CXXC-type | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000389506 | 7 | 36 | 1147_1195 | 1362.0 | 3970.0 | Zinc finger | CXXC-type | |
| Tgene | KMT2A | chr4:87968746 | chr11:118354897 | ENST00000534358 | 7 | 36 | 1147_1195 | 1362.0 | 3973.0 | Zinc finger | CXXC-type | |
| Tgene | KMT2A | chr4:87968747 | chr11:118354896 | ENST00000354520 | 7 | 35 | 1147_1195 | 1362.0 | 3932.0 | Zinc finger | CXXC-type | |
| Tgene | KMT2A | chr4:87968747 | chr11:118354896 | ENST00000389506 | 7 | 36 | 1147_1195 | 1362.0 | 3970.0 | Zinc finger | CXXC-type | |
| Tgene | KMT2A | chr4:87968747 | chr11:118354896 | ENST00000534358 | 7 | 36 | 1147_1195 | 1362.0 | 3973.0 | Zinc finger | CXXC-type | |
| Tgene | KMT2A | chr4:87968752 | chr11:118359327 | ENST00000354520 | 8 | 35 | 1147_1195 | 1406.0 | 3932.0 | Zinc finger | CXXC-type | |
| Tgene | KMT2A | chr4:87968752 | chr11:118359327 | ENST00000389506 | 9 | 36 | 1147_1195 | 1444.0 | 3970.0 | Zinc finger | CXXC-type | |
| Tgene | KMT2A | chr4:87968752 | chr11:118359327 | ENST00000389506 | 9 | 36 | 1431_1482 | 1444.0 | 3970.0 | Zinc finger | PHD-type 1 | |
| Tgene | KMT2A | chr4:87968752 | chr11:118359327 | ENST00000534358 | 9 | 36 | 1147_1195 | 1444.0 | 3973.0 | Zinc finger | CXXC-type | |
| Tgene | KMT2A | chr4:87968752 | chr11:118359327 | ENST00000534358 | 9 | 36 | 1431_1482 | 1444.0 | 3973.0 | Zinc finger | PHD-type 1 | |
| Tgene | KMT2A | chr4:88005317 | chr11:118354896 | ENST00000354520 | 7 | 35 | 1147_1195 | 1362.0 | 3932.0 | Zinc finger | CXXC-type | |
| Tgene | KMT2A | chr4:88005317 | chr11:118354896 | ENST00000389506 | 7 | 36 | 1147_1195 | 1362.0 | 3970.0 | Zinc finger | CXXC-type | |
| Tgene | KMT2A | chr4:88005317 | chr11:118354896 | ENST00000534358 | 7 | 36 | 1147_1195 | 1362.0 | 3973.0 | Zinc finger | CXXC-type |
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Fusion Protein Structures |
| PDB and CIF files of the predicted fusion proteins * Here we show the 3D structure of the fusion proteins using Mol*. AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Model confidence is shown from the pLDDT values per residue. pLDDT corresponds to the model’s prediction of its score on the local Distance Difference Test. It is a measure of local accuracy (from AlphfaFold website). To color code individual residues, we transformed individual PDB files into CIF format. |
| Fusion protein PDB link (fusion AA seq ID in FusionPDB) | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | AA seq | Len(AA seq) |
| PDB file (1144) >>>1144.pdbFusion protein BP residue: 46 CIF file (1144) >>>1144.cif | AFF1 | chr4 | 87967438 | + | KMT2A | chr11 | 118359328 | MAAQSSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKFVYC QVCCEPFHKFCLEENERPLEDQLENWCCRRCKFCHVCGRQHQATKQLLEC NKCRNSYHPECLGPNYPTKPTKKKKVWICTKCVRCKSCGSTTPGKGWDAQ WSHDFSLCHDCAKLFAKGNFCPLCDKCYDDDDYESKMMQCGKCDRWVHSK CENLSDEMYEILSNLPESVAYTCVNCTERHPAEWRLALEKELQISLKQVL TALLNSRTTSHLLRYRQAAKPPDLNPETEESIPSRSSPEGPDPPVLTEVS KQDDQQPLDLEGVKRKMDQGNYTSVLEFSDDIVKIIQAAINSDGGQPEIK KANSMVKSFFIRQMERVFPWFSVKKSRFWEPNKVSSNSGMLPNAVLPPSL DHNYAQWQEREENSHTEQPPLMKKIIPAPKPKGPGEPDSPTPLHPPTPPI LSTDRSREDSPELNPPPGIEDNRQCALCLTYGDDSANDAGRLLYIGQNEW THVNCALWSAEVFEDDDGSLKNVHMAVIRGKQLRCEFCQKPGATVGCCLT SCTSNYHFMCSRAKNCVFLDDKKVYCQRHRDLIKGEVVPENGFEVFRRVF VDFEGISLRRKFLNGLEPENIHMMIGSMTIDCLGILNDLSDCEDKLFPIG YQCSRVYWSTTDARKRCVYTCKIVECRPPVVEPDINSTVEHDENRTIAHS PTSFTESSSKESQNTAEIISPPSPDRPPHSQTSGSCYYHVISKVPRIRTP SYSPTQRSPGCRPLPSAGSPTPTTHEIVTVGDPLLSSGLRSIGSRRHSTS SLSPQRSKLRIMSPMRTGNTYSRNNVSSVSTTGTATDLESSAKVVDHVLG PLNSSTSLGQNTSTSSNLQRTVVTVGNKNSHLDGSSSSEMKQSSASDLVS KSSSLKGEKTKVLSSKSSEGSAHNVAYPGIPKLAPQVHNTTSRELNVSKI GSFAEPSSVSFSSKEALSFPHLHLRGQRNDRDQHTDSTQSANSSPDEDTE VKTLKLSGMSNRSSIINEHMGSSSRDRRQKGKKSCKETFKEKHSSKSFLE PGQVTTGEEGNLKPEFMDEVLTPEYMGQRPCNNVSSDKIGDKGLSMPGVP KAPPMQVEGSAKELQAPRKRTVKVTLTPLKMENESQSKNALKESSPASPL QIESTSPTEPISASENPGDGPVAQPSPNNTSCQDSQSNNYQNLPVQDRNL MLPDGPKPQEDGSFKRRYPRRSARARSNMFFGLTPLYGVRSYGEEDIPFY SSSTGKKRGKRSAEGQVDGADDLSTSDEDDLYYYNFTRTVISSGGEERLA SHNLFREEEQCDLPKISQLDGVDDGTESDTSVTATTRKSSQIPKRNGKEN GTENLKIDRPEDAGEKEHVTKSSVGHKNEPKMDNCHSVSRVKTQGQDSLE AQLSSLESSRRVHTSTPSDKNLLDTYNTELLKSDSDNNNSDDCGNILPSD IMDFVLKNTPSMQALGESPESSSSELLNLGEGLGLDSNREKDMGLFEVFS QQLPTTEPVDSSVSSSISAEEQFELPLELPSDLSVLTTRSPTVPSQNPSR LAVISDSGEKRVTITEKSVASSESDPALLSPGVDPTPEGHMTPDHFIQGH MDADHISSPPCGSVEQGHGNNQDLTRNSSTPGLQVPVSPTVPIQNQKYVP NSTDSPGPSQISNAAVQTTPPHLKPATEKLIVVNQNMQPLYVLQTLPNGV TQKIQLTSSVSSTPSVMETNTSVLGPMGGGLTLTTGLNPSLPTSQSLFPS ASKGLLPMSHHQHLHSFPAATQSSFPPNISNPPSGLLIGVQPPPDPQLLV SESSQRTDLSTTVATPSSGLKKRPISRLQTRKNKKLAPSSTPSNIAPSDV VSNMTLINFTPSQLPNHPSLLDLGSLNTSSHRTVPNIIKRSKSSIMYFEP APLLPQSVGGTAATAAGTSTISQDTSHLTSGSVSGLASSSSVLNVVSMQT TTTPTSSASVPGHVTLTNPRLLGTPDIGSISNLLIKASQQSLGIQDQPVA LPPSSGMFPQLGTSQTPSTAAITAASSICVLPSTQTTGITAASPSGEADE HYQLQHVNQLLASKTGIHSSQRDLDSASGPQVSNFTQTVDAPNSMGLEQN KALSSAVQASPTSPGGSPSSPSSGQRSASPSVPGPTKPKPKTKRFQLPLD KGNGKKHKVSHLRTSSSEAHIPDQETTSLTSGTGTPGAEAEQQDTASVEQ SSQKECGQPAGQVAVLPEVQVTQNPANEQESAEPKTVEEEESNFSSPLML WLQQEQKRKESITEKKPKKGLVFEISSDDGFQICAESIEDAWKSLTDKVQ EARSNARLKQLSFAGVNGLRMLGILHDAVVFLIEQLSGAKHCRNYKFRFH KPEEANEPPLNPHGSARAEVHLRKSAFDMFNFLASKHRQPPEYNPNDEEE EEVQLKSARRATSMDLPMPMRFRHLKKTSKEAVGVYRSPIHGRGLFCKRN IDAGEMVIEYAGNVIRSIQTDKREKYYDSKGIGCYMFRIDDSEVVDATMH GNAARFINHSCEPNCYSRVINIDGQKHIVIFAMRKIYRGEELTYDYKFPI | 2571 | |
| 3D view using mol* of 1144 (AA BP:46) | ||||||||||
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| PDB file (1147) >>>1147.pdbFusion protein BP residue: 46 CIF file (1147) >>>1147.cif | AFF1 | chr4 | 87967438 | + | KMT2A | chr11 | 118359328 | MAAQSSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKFVYC QVCCEPFHKFCLEENERPLEDQLENWCCRRCKFCHVCGRQHQATKQLLEC NKCRNSYHPECLGPNYPTKPTKKKKVWICTKCVRCKSCGSTTPGKGWDAQ WSHDFSLCHDCAKLFAKGNFCPLCDKCYDDDDYESKMMQCGKCDRWVHSK CENLSGTEDEMYEILSNLPESVAYTCVNCTERHPAEWRLALEKELQISLK QVLTALLNSRTTSHLLRYRQAAKPPDLNPETEESIPSRSSPEGPDPPVLT EVSKQDDQQPLDLEGVKRKMDQGNYTSVLEFSDDIVKIIQAAINSDGGQP EIKKANSMVKSFFIRQMERVFPWFSVKKSRFWEPNKVSSNSGMLPNAVLP PSLDHNYAQWQEREENSHTEQPPLMKKIIPAPKPKGPGEPDSPTPLHPPT PPILSTDRSREDSPELNPPPGIEDNRQCALCLTYGDDSANDAGRLLYIGQ NEWTHVNCALWSAEVFEDDDGSLKNVHMAVIRGKQLRCEFCQKPGATVGC CLTSCTSNYHFMCSRAKNCVFLDDKKVYCQRHRDLIKGEVVPENGFEVFR RVFVDFEGISLRRKFLNGLEPENIHMMIGSMTIDCLGILNDLSDCEDKLF PIGYQCSRVYWSTTDARKRCVYTCKIVECRPPVVEPDINSTVEHDENRTI AHSPTSFTESSSKESQNTAEIISPPSPDRPPHSQTSGSCYYHVISKVPRI RTPSYSPTQRSPGCRPLPSAGSPTPTTHEIVTVGDPLLSSGLRSIGSRRH STSSLSPQRSKLRIMSPMRTGNTYSRNNVSSVSTTGTATDLESSAKVVDH VLGPLNSSTSLGQNTSTSSNLQRTVVTVGNKNSHLDGSSSSEMKQSSASD LVSKSSSLKGEKTKVLSSKSSEGSAHNVAYPGIPKLAPQVHNTTSRELNV SKIGSFAEPSSVSFSSKEALSFPHLHLRGQRNDRDQHTDSTQSANSSPDE DTEVKTLKLSGMSNRSSIINEHMGSSSRDRRQKGKKSCKETFKEKHSSKS FLEPGQVTTGEEGNLKPEFMDEVLTPEYMGQRPCNNVSSDKIGDKGLSMP GVPKAPPMQVEGSAKELQAPRKRTVKVTLTPLKMENESQSKNALKESSPA SPLQIESTSPTEPISASENPGDGPVAQPSPNNTSCQDSQSNNYQNLPVQD RNLMLPDGPKPQEDGSFKRRYPRRSARARSNMFFGLTPLYGVRSYGEEDI PFYSSSTGKKRGKRSAEGQVDGADDLSTSDEDDLYYYNFTRTVISSGGEE RLASHNLFREEEQCDLPKISQLDGVDDGTESDTSVTATTRKSSQIPKRNG KENGTENLKIDRPEDAGEKEHVTKSSVGHKNEPKMDNCHSVSRVKTQGQD SLEAQLSSLESSRRVHTSTPSDKNLLDTYNTELLKSDSDNNNSDDCGNIL PSDIMDFVLKNTPSMQALGESPESSSSELLNLGEGLGLDSNREKDMGLFE VFSQQLPTTEPVDSSVSSSISAEEQFELPLELPSDLSVLTTRSPTVPSQN PSRLAVISDSGEKRVTITEKSVASSESDPALLSPGVDPTPEGHMTPDHFI QGHMDADHISSPPCGSVEQGHGNNQDLTRNSSTPGLQVPVSPTVPIQNQK YVPNSTDSPGPSQISNAAVQTTPPHLKPATEKLIVVNQNMQPLYVLQTLP NGVTQKIQLTSSVSSTPSVMETNTSVLGPMGGGLTLTTGLNPSLPTSQSL FPSASKGLLPMSHHQHLHSFPAATQSSFPPNISNPPSGLLIGVQPPPDPQ LLVSESSQRTDLSTTVATPSSGLKKRPISRLQTRKNKKLAPSSTPSNIAP SDVVSNMTLINFTPSQLPNHPSLLDLGSLNTSSHRTVPNIIKRSKSSIMY FEPAPLLPQSVGGTAATAAGTSTISQDTSHLTSGSVSGLASSSSVLNVVS MQTTTTPTSSASVPGHVTLTNPRLLGTPDIGSISNLLIKASQQSLGIQDQ PVALPPSSGMFPQLGTSQTPSTAAITAASSICVLPSTQTTGITAASPSGE ADEHYQLQHVNQLLASKTGIHSSQRDLDSASGPQVSNFTQTVDAPNSMGL EQNKALSSAVQASPTSPGGSPSSPSSGQRSASPSVPGPTKPKPKTKRFQL PLDKGNGKKHKVSHLRTSSSEAHIPDQETTSLTSGTGTPGAEAEQQDTAS VEQSSQKECGQPAGQVAVLPEVQVTQNPANEQESAEPKTVEEEESNFSSP LMLWLQQEQKRKESITEKKPKKGLVFEISSDDGFQICAESIEDAWKSLTD KVQEARSNARLKQLSFAGVNGLRMLGILHDAVVFLIEQLSGAKHCRNYKF RFHKPEEANEPPLNPHGSARAEVHLRKSAFDMFNFLASKHRQPPEYNPND EEEEEVQLKSARRATSMDLPMPMRFRHLKKTSKEAVGVYRSPIHGRGLFC KRNIDAGEMVIEYAGNVIRSIQTDKREKYYDSKGIGCYMFRIDDSEVVDA TMHGNAARFINHSCEPNCYSRVINIDGQKHIVIFAMRKIYRGEELTYDYK | 2574 | |
| 3D view using mol* of 1147 (AA BP:46) | ||||||||||
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| PDB file (1150) >>>1150.pdbFusion protein BP residue: 56 CIF file (1150) >>>1150.cif | AFF1 | chr4 | 87967438 | + | KMT2A | chr11 | 118359328 | METMAFTERVNSSGNSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPL FGEPYKFVYCQVCCEPFHKFCLEENERPLEDQLENWCCRRCKFCHVCGRQ HQATKQLLECNKCRNSYHPECLGPNYPTKPTKKKKVWICTKCVRCKSCGS TTPGKGWDAQWSHDFSLCHDCAKLFAKGNFCPLCDKCYDDDDYESKMMQC GKCDRWVHSKCENLSDEMYEILSNLPESVAYTCVNCTERHPAEWRLALEK ELQISLKQVLTALLNSRTTSHLLRYRQAAKPPDLNPETEESIPSRSSPEG PDPPVLTEVSKQDDQQPLDLEGVKRKMDQGNYTSVLEFSDDIVKIIQAAI NSDGGQPEIKKANSMVKSFFIRQMERVFPWFSVKKSRFWEPNKVSSNSGM LPNAVLPPSLDHNYAQWQEREENSHTEQPPLMKKIIPAPKPKGPGEPDSP TPLHPPTPPILSTDRSREDSPELNPPPGIEDNRQCALCLTYGDDSANDAG RLLYIGQNEWTHVNCALWSAEVFEDDDGSLKNVHMAVIRGKQLRCEFCQK PGATVGCCLTSCTSNYHFMCSRAKNCVFLDDKKVYCQRHRDLIKGEVVPE NGFEVFRRVFVDFEGISLRRKFLNGLEPENIHMMIGSMTIDCLGILNDLS DCEDKLFPIGYQCSRVYWSTTDARKRCVYTCKIVECRPPVVEPDINSTVE HDENRTIAHSPTSFTESSSKESQNTAEIISPPSPDRPPHSQTSGSCYYHV ISKVPRIRTPSYSPTQRSPGCRPLPSAGSPTPTTHEIVTVGDPLLSSGLR SIGSRRHSTSSLSPQRSKLRIMSPMRTGNTYSRNNVSSVSTTGTATDLES SAKVVDHVLGPLNSSTSLGQNTSTSSNLQRTVVTVGNKNSHLDGSSSSEM KQSSASDLVSKSSSLKGEKTKVLSSKSSEGSAHNVAYPGIPKLAPQVHNT TSRELNVSKIGSFAEPSSVSFSSKEALSFPHLHLRGQRNDRDQHTDSTQS ANSSPDEDTEVKTLKLSGMSNRSSIINEHMGSSSRDRRQKGKKSCKETFK EKHSSKSFLEPGQVTTGEEGNLKPEFMDEVLTPEYMGQRPCNNVSSDKIG DKGLSMPGVPKAPPMQVEGSAKELQAPRKRTVKVTLTPLKMENESQSKNA LKESSPASPLQIESTSPTEPISASENPGDGPVAQPSPNNTSCQDSQSNNY QNLPVQDRNLMLPDGPKPQEDGSFKRRYPRRSARARSNMFFGLTPLYGVR SYGEEDIPFYSSSTGKKRGKRSAEGQVDGADDLSTSDEDDLYYYNFTRTV ISSGGEERLASHNLFREEEQCDLPKISQLDGVDDGTESDTSVTATTRKSS QIPKRNGKENGTENLKIDRPEDAGEKEHVTKSSVGHKNEPKMDNCHSVSR VKTQGQDSLEAQLSSLESSRRVHTSTPSDKNLLDTYNTELLKSDSDNNNS DDCGNILPSDIMDFVLKNTPSMQALGESPESSSSELLNLGEGLGLDSNRE KDMGLFEVFSQQLPTTEPVDSSVSSSISAEEQFELPLELPSDLSVLTTRS PTVPSQNPSRLAVISDSGEKRVTITEKSVASSESDPALLSPGVDPTPEGH MTPDHFIQGHMDADHISSPPCGSVEQGHGNNQDLTRNSSTPGLQVPVSPT VPIQNQKYVPNSTDSPGPSQISNAAVQTTPPHLKPATEKLIVVNQNMQPL YVLQTLPNGVTQKIQLTSSVSSTPSVMETNTSVLGPMGGGLTLTTGLNPS LPTSQSLFPSASKGLLPMSHHQHLHSFPAATQSSFPPNISNPPSGLLIGV QPPPDPQLLVSESSQRTDLSTTVATPSSGLKKRPISRLQTRKNKKLAPSS TPSNIAPSDVVSNMTLINFTPSQLPNHPSLLDLGSLNTSSHRTVPNIIKR SKSSIMYFEPAPLLPQSVGGTAATAAGTSTISQDTSHLTSGSVSGLASSS SVLNVVSMQTTTTPTSSASVPGHVTLTNPRLLGTPDIGSISNLLIKASQQ SLGIQDQPVALPPSSGMFPQLGTSQTPSTAAITAASSICVLPSTQTTGIT AASPSGEADEHYQLQHVNQLLASKTGIHSSQRDLDSASGPQVSNFTQTVD APNSMGLEQNKALSSAVQASPTSPGGSPSSPSSGQRSASPSVPGPTKPKP KTKRFQLPLDKGNGKKHKVSHLRTSSSEAHIPDQETTSLTSGTGTPGAEA EQQDTASVEQSSQKECGQPAGQVAVLPEVQVTQNPANEQESAEPKTVEEE ESNFSSPLMLWLQQEQKRKESITEKKPKKGLVFEISSDDGFQICAESIED AWKSLTDKVQEARSNARLKQLSFAGVNGLRMLGILHDAVVFLIEQLSGAK HCRNYKFRFHKPEEANEPPLNPHGSARAEVHLRKSAFDMFNFLASKHRQP PEYNPNDEEEEEVQLKSARRATSMDLPMPMRFRHLKKTSKEAVGVYRSPI HGRGLFCKRNIDAGEMVIEYAGNVIRSIQTDKREKYYDSKGIGCYMFRID DSEVVDATMHGNAARFINHSCEPNCYSRVINIDGQKHIVIFAMRKIYRGE | 2581 | |
| 3D view using mol* of 1150 (AA BP:56) | ||||||||||
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| PDB file (1152) >>>1152.pdbFusion protein BP residue: 56 CIF file (1152) >>>1152.cif | AFF1 | chr4 | 87967438 | + | KMT2A | chr11 | 118359328 | METMAFTERVNSSGNSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPL FGEPYKFVYCQVCCEPFHKFCLEENERPLEDQLENWCCRRCKFCHVCGRQ HQATKQLLECNKCRNSYHPECLGPNYPTKPTKKKKVWICTKCVRCKSCGS TTPGKGWDAQWSHDFSLCHDCAKLFAKGNFCPLCDKCYDDDDYESKMMQC GKCDRWVHSKCENLSGTEDEMYEILSNLPESVAYTCVNCTERHPAEWRLA LEKELQISLKQVLTALLNSRTTSHLLRYRQAAKPPDLNPETEESIPSRSS PEGPDPPVLTEVSKQDDQQPLDLEGVKRKMDQGNYTSVLEFSDDIVKIIQ AAINSDGGQPEIKKANSMVKSFFIRQMERVFPWFSVKKSRFWEPNKVSSN SGMLPNAVLPPSLDHNYAQWQEREENSHTEQPPLMKKIIPAPKPKGPGEP DSPTPLHPPTPPILSTDRSREDSPELNPPPGIEDNRQCALCLTYGDDSAN DAGRLLYIGQNEWTHVNCALWSAEVFEDDDGSLKNVHMAVIRGKQLRCEF CQKPGATVGCCLTSCTSNYHFMCSRAKNCVFLDDKKVYCQRHRDLIKGEV VPENGFEVFRRVFVDFEGISLRRKFLNGLEPENIHMMIGSMTIDCLGILN DLSDCEDKLFPIGYQCSRVYWSTTDARKRCVYTCKIVECRPPVVEPDINS TVEHDENRTIAHSPTSFTESSSKESQNTAEIISPPSPDRPPHSQTSGSCY YHVISKVPRIRTPSYSPTQRSPGCRPLPSAGSPTPTTHEIVTVGDPLLSS GLRSIGSRRHSTSSLSPQRSKLRIMSPMRTGNTYSRNNVSSVSTTGTATD LESSAKVVDHVLGPLNSSTSLGQNTSTSSNLQRTVVTVGNKNSHLDGSSS SEMKQSSASDLVSKSSSLKGEKTKVLSSKSSEGSAHNVAYPGIPKLAPQV HNTTSRELNVSKIGSFAEPSSVSFSSKEALSFPHLHLRGQRNDRDQHTDS TQSANSSPDEDTEVKTLKLSGMSNRSSIINEHMGSSSRDRRQKGKKSCKE TFKEKHSSKSFLEPGQVTTGEEGNLKPEFMDEVLTPEYMGQRPCNNVSSD KIGDKGLSMPGVPKAPPMQVEGSAKELQAPRKRTVKVTLTPLKMENESQS KNALKESSPASPLQIESTSPTEPISASENPGDGPVAQPSPNNTSCQDSQS NNYQNLPVQDRNLMLPDGPKPQEDGSFKRRYPRRSARARSNMFFGLTPLY GVRSYGEEDIPFYSSSTGKKRGKRSAEGQVDGADDLSTSDEDDLYYYNFT RTVISSGGEERLASHNLFREEEQCDLPKISQLDGVDDGTESDTSVTATTR KSSQIPKRNGKENGTENLKIDRPEDAGEKEHVTKSSVGHKNEPKMDNCHS VSRVKTQGQDSLEAQLSSLESSRRVHTSTPSDKNLLDTYNTELLKSDSDN NNSDDCGNILPSDIMDFVLKNTPSMQALGESPESSSSELLNLGEGLGLDS NREKDMGLFEVFSQQLPTTEPVDSSVSSSISAEEQFELPLELPSDLSVLT TRSPTVPSQNPSRLAVISDSGEKRVTITEKSVASSESDPALLSPGVDPTP EGHMTPDHFIQGHMDADHISSPPCGSVEQGHGNNQDLTRNSSTPGLQVPV SPTVPIQNQKYVPNSTDSPGPSQISNAAVQTTPPHLKPATEKLIVVNQNM QPLYVLQTLPNGVTQKIQLTSSVSSTPSVMETNTSVLGPMGGGLTLTTGL NPSLPTSQSLFPSASKGLLPMSHHQHLHSFPAATQSSFPPNISNPPSGLL IGVQPPPDPQLLVSESSQRTDLSTTVATPSSGLKKRPISRLQTRKNKKLA PSSTPSNIAPSDVVSNMTLINFTPSQLPNHPSLLDLGSLNTSSHRTVPNI IKRSKSSIMYFEPAPLLPQSVGGTAATAAGTSTISQDTSHLTSGSVSGLA SSSSVLNVVSMQTTTTPTSSASVPGHVTLTNPRLLGTPDIGSISNLLIKA SQQSLGIQDQPVALPPSSGMFPQLGTSQTPSTAAITAASSICVLPSTQTT GITAASPSGEADEHYQLQHVNQLLASKTGIHSSQRDLDSASGPQVSNFTQ TVDAPNSMGLEQNKALSSAVQASPTSPGGSPSSPSSGQRSASPSVPGPTK PKPKTKRFQLPLDKGNGKKHKVSHLRTSSSEAHIPDQETTSLTSGTGTPG AEAEQQDTASVEQSSQKECGQPAGQVAVLPEVQVTQNPANEQESAEPKTV EEEESNFSSPLMLWLQQEQKRKESITEKKPKKGLVFEISSDDGFQICAES IEDAWKSLTDKVQEARSNARLKQLSFAGVNGLRMLGILHDAVVFLIEQLS GAKHCRNYKFRFHKPEEANEPPLNPHGSARAEVHLRKSAFDMFNFLASKH RQPPEYNPNDEEEEEVQLKSARRATSMDLPMPMRFRHLKKTSKEAVGVYR SPIHGRGLFCKRNIDAGEMVIEYAGNVIRSIQTDKREKYYDSKGIGCYMF RIDDSEVVDATMHGNAARFINHSCEPNCYSRVINIDGQKHIVIFAMRKIY | 2584 | |
| 3D view using mol* of 1152 (AA BP:56) | ||||||||||
| ||||||||||
| PDB file (1158) >>>1158.pdbFusion protein BP residue: 46 CIF file (1158) >>>1158.cif | AFF1 | chr4 | 87967438 | + | KMT2A | chr11 | 118354897 | MAAQSSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKEKPP PVNKQENAGTLNILSTLSNGNSSKQKIPADGVHRIRVDFKFVYCQVCCEP FHKFCLEENERPLEDQLENWCCRRCKFCHVCGRQHQATKQLLECNKCRNS YHPECLGPNYPTKPTKKKKVWICTKCVRCKSCGSTTPGKGWDAQWSHDFS LCHDCAKLFAKGNFCPLCDKCYDDDDYESKMMQCGKCDRWVHSKCENLSD EMYEILSNLPESVAYTCVNCTERHPAEWRLALEKELQISLKQVLTALLNS RTTSHLLRYRQAAKPPDLNPETEESIPSRSSPEGPDPPVLTEVSKQDDQQ PLDLEGVKRKMDQGNYTSVLEFSDDIVKIIQAAINSDGGQPEIKKANSMV KSFFIRQMERVFPWFSVKKSRFWEPNKVSSNSGMLPNAVLPPSLDHNYAQ WQEREENSHTEQPPLMKKIIPAPKPKGPGEPDSPTPLHPPTPPILSTDRS REDSPELNPPPGIEDNRQCALCLTYGDDSANDAGRLLYIGQNEWTHVNCA LWSAEVFEDDDGSLKNVHMAVIRGKQLRCEFCQKPGATVGCCLTSCTSNY HFMCSRAKNCVFLDDKKVYCQRHRDLIKGEVVPENGFEVFRRVFVDFEGI SLRRKFLNGLEPENIHMMIGSMTIDCLGILNDLSDCEDKLFPIGYQCSRV YWSTTDARKRCVYTCKIVECRPPVVEPDINSTVEHDENRTIAHSPTSFTE SSSKESQNTAEIISPPSPDRPPHSQTSGSCYYHVISKVPRIRTPSYSPTQ RSPGCRPLPSAGSPTPTTHEIVTVGDPLLSSGLRSIGSRRHSTSSLSPQR SKLRIMSPMRTGNTYSRNNVSSVSTTGTATDLESSAKVVDHVLGPLNSST SLGQNTSTSSNLQRTVVTVGNKNSHLDGSSSSEMKQSSASDLVSKSSSLK GEKTKVLSSKSSEGSAHNVAYPGIPKLAPQVHNTTSRELNVSKIGSFAEP SSVSFSSKEALSFPHLHLRGQRNDRDQHTDSTQSANSSPDEDTEVKTLKL SGMSNRSSIINEHMGSSSRDRRQKGKKSCKETFKEKHSSKSFLEPGQVTT GEEGNLKPEFMDEVLTPEYMGQRPCNNVSSDKIGDKGLSMPGVPKAPPMQ VEGSAKELQAPRKRTVKVTLTPLKMENESQSKNALKESSPASPLQIESTS PTEPISASENPGDGPVAQPSPNNTSCQDSQSNNYQNLPVQDRNLMLPDGP KPQEDGSFKRRYPRRSARARSNMFFGLTPLYGVRSYGEEDIPFYSSSTGK KRGKRSAEGQVDGADDLSTSDEDDLYYYNFTRTVISSGGEERLASHNLFR EEEQCDLPKISQLDGVDDGTESDTSVTATTRKSSQIPKRNGKENGTENLK IDRPEDAGEKEHVTKSSVGHKNEPKMDNCHSVSRVKTQGQDSLEAQLSSL ESSRRVHTSTPSDKNLLDTYNTELLKSDSDNNNSDDCGNILPSDIMDFVL KNTPSMQALGESPESSSSELLNLGEGLGLDSNREKDMGLFEVFSQQLPTT EPVDSSVSSSISAEEQFELPLELPSDLSVLTTRSPTVPSQNPSRLAVISD SGEKRVTITEKSVASSESDPALLSPGVDPTPEGHMTPDHFIQGHMDADHI SSPPCGSVEQGHGNNQDLTRNSSTPGLQVPVSPTVPIQNQKYVPNSTDSP GPSQISNAAVQTTPPHLKPATEKLIVVNQNMQPLYVLQTLPNGVTQKIQL TSSVSSTPSVMETNTSVLGPMGGGLTLTTGLNPSLPTSQSLFPSASKGLL PMSHHQHLHSFPAATQSSFPPNISNPPSGLLIGVQPPPDPQLLVSESSQR TDLSTTVATPSSGLKKRPISRLQTRKNKKLAPSSTPSNIAPSDVVSNMTL INFTPSQLPNHPSLLDLGSLNTSSHRTVPNIIKRSKSSIMYFEPAPLLPQ SVGGTAATAAGTSTISQDTSHLTSGSVSGLASSSSVLNVVSMQTTTTPTS SASVPGHVTLTNPRLLGTPDIGSISNLLIKASQQSLGIQDQPVALPPSSG MFPQLGTSQTPSTAAITAASSICVLPSTQTTGITAASPSGEADEHYQLQH VNQLLASKTGIHSSQRDLDSASGPQVSNFTQTVDAPNSMGLEQNKALSSA VQASPTSPGGSPSSPSSGQRSASPSVPGPTKPKPKTKRFQLPLDKGNGKK HKVSHLRTSSSEAHIPDQETTSLTSGTGTPGAEAEQQDTASVEQSSQKEC GQPAGQVAVLPEVQVTQNPANEQESAEPKTVEEEESNFSSPLMLWLQQEQ KRKESITEKKPKKGLVFEISSDDGFQICAESIEDAWKSLTDKVQEARSNA RLKQLSFAGVNGLRMLGILHDAVVFLIEQLSGAKHCRNYKFRFHKPEEAN EPPLNPHGSARAEVHLRKSAFDMFNFLASKHRQPPEYNPNDEEEEEVQLK SARRATSMDLPMPMRFRHLKKTSKEAVGVYRSPIHGRGLFCKRNIDAGEM VIEYAGNVIRSIQTDKREKYYDSKGIGCYMFRIDDSEVVDATMHGNAARF INHSCEPNCYSRVINIDGQKHIVIFAMRKIYRGEELTYDYKFPIEDASNK | 2615 | |
| 3D view using mol* of 1158 (AA BP:46) | ||||||||||
| ||||||||||
| PDB file (1163) >>>1163.pdbFusion protein BP residue: 56 CIF file (1163) >>>1163.cif | AFF1 | chr4 | 87967438 | + | KMT2A | chr11 | 118354897 | METMAFTERVNSSGNSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPL FGEPYKEKPPPVNKQENAGTLNILSTLSNGNSSKQKIPADGVHRIRVDFK FVYCQVCCEPFHKFCLEENERPLEDQLENWCCRRCKFCHVCGRQHQATKQ LLECNKCRNSYHPECLGPNYPTKPTKKKKVWICTKCVRCKSCGSTTPGKG WDAQWSHDFSLCHDCAKLFAKGNFCPLCDKCYDDDDYESKMMQCGKCDRW VHSKCENLSDEMYEILSNLPESVAYTCVNCTERHPAEWRLALEKELQISL KQVLTALLNSRTTSHLLRYRQAAKPPDLNPETEESIPSRSSPEGPDPPVL TEVSKQDDQQPLDLEGVKRKMDQGNYTSVLEFSDDIVKIIQAAINSDGGQ PEIKKANSMVKSFFIRQMERVFPWFSVKKSRFWEPNKVSSNSGMLPNAVL PPSLDHNYAQWQEREENSHTEQPPLMKKIIPAPKPKGPGEPDSPTPLHPP TPPILSTDRSREDSPELNPPPGIEDNRQCALCLTYGDDSANDAGRLLYIG QNEWTHVNCALWSAEVFEDDDGSLKNVHMAVIRGKQLRCEFCQKPGATVG CCLTSCTSNYHFMCSRAKNCVFLDDKKVYCQRHRDLIKGEVVPENGFEVF RRVFVDFEGISLRRKFLNGLEPENIHMMIGSMTIDCLGILNDLSDCEDKL FPIGYQCSRVYWSTTDARKRCVYTCKIVECRPPVVEPDINSTVEHDENRT IAHSPTSFTESSSKESQNTAEIISPPSPDRPPHSQTSGSCYYHVISKVPR IRTPSYSPTQRSPGCRPLPSAGSPTPTTHEIVTVGDPLLSSGLRSIGSRR HSTSSLSPQRSKLRIMSPMRTGNTYSRNNVSSVSTTGTATDLESSAKVVD HVLGPLNSSTSLGQNTSTSSNLQRTVVTVGNKNSHLDGSSSSEMKQSSAS DLVSKSSSLKGEKTKVLSSKSSEGSAHNVAYPGIPKLAPQVHNTTSRELN VSKIGSFAEPSSVSFSSKEALSFPHLHLRGQRNDRDQHTDSTQSANSSPD EDTEVKTLKLSGMSNRSSIINEHMGSSSRDRRQKGKKSCKETFKEKHSSK SFLEPGQVTTGEEGNLKPEFMDEVLTPEYMGQRPCNNVSSDKIGDKGLSM PGVPKAPPMQVEGSAKELQAPRKRTVKVTLTPLKMENESQSKNALKESSP ASPLQIESTSPTEPISASENPGDGPVAQPSPNNTSCQDSQSNNYQNLPVQ DRNLMLPDGPKPQEDGSFKRRYPRRSARARSNMFFGLTPLYGVRSYGEED IPFYSSSTGKKRGKRSAEGQVDGADDLSTSDEDDLYYYNFTRTVISSGGE ERLASHNLFREEEQCDLPKISQLDGVDDGTESDTSVTATTRKSSQIPKRN GKENGTENLKIDRPEDAGEKEHVTKSSVGHKNEPKMDNCHSVSRVKTQGQ DSLEAQLSSLESSRRVHTSTPSDKNLLDTYNTELLKSDSDNNNSDDCGNI LPSDIMDFVLKNTPSMQALGESPESSSSELLNLGEGLGLDSNREKDMGLF EVFSQQLPTTEPVDSSVSSSISAEEQFELPLELPSDLSVLTTRSPTVPSQ NPSRLAVISDSGEKRVTITEKSVASSESDPALLSPGVDPTPEGHMTPDHF IQGHMDADHISSPPCGSVEQGHGNNQDLTRNSSTPGLQVPVSPTVPIQNQ KYVPNSTDSPGPSQISNAAVQTTPPHLKPATEKLIVVNQNMQPLYVLQTL PNGVTQKIQLTSSVSSTPSVMETNTSVLGPMGGGLTLTTGLNPSLPTSQS LFPSASKGLLPMSHHQHLHSFPAATQSSFPPNISNPPSGLLIGVQPPPDP QLLVSESSQRTDLSTTVATPSSGLKKRPISRLQTRKNKKLAPSSTPSNIA PSDVVSNMTLINFTPSQLPNHPSLLDLGSLNTSSHRTVPNIIKRSKSSIM YFEPAPLLPQSVGGTAATAAGTSTISQDTSHLTSGSVSGLASSSSVLNVV SMQTTTTPTSSASVPGHVTLTNPRLLGTPDIGSISNLLIKASQQSLGIQD QPVALPPSSGMFPQLGTSQTPSTAAITAASSICVLPSTQTTGITAASPSG EADEHYQLQHVNQLLASKTGIHSSQRDLDSASGPQVSNFTQTVDAPNSMG LEQNKALSSAVQASPTSPGGSPSSPSSGQRSASPSVPGPTKPKPKTKRFQ LPLDKGNGKKHKVSHLRTSSSEAHIPDQETTSLTSGTGTPGAEAEQQDTA SVEQSSQKECGQPAGQVAVLPEVQVTQNPANEQESAEPKTVEEEESNFSS PLMLWLQQEQKRKESITEKKPKKGLVFEISSDDGFQICAESIEDAWKSLT DKVQEARSNARLKQLSFAGVNGLRMLGILHDAVVFLIEQLSGAKHCRNYK FRFHKPEEANEPPLNPHGSARAEVHLRKSAFDMFNFLASKHRQPPEYNPN DEEEEEVQLKSARRATSMDLPMPMRFRHLKKTSKEAVGVYRSPIHGRGLF CKRNIDAGEMVIEYAGNVIRSIQTDKREKYYDSKGIGCYMFRIDDSEVVD ATMHGNAARFINHSCEPNCYSRVINIDGQKHIVIFAMRKIYRGEELTYDY | 2625 | |
| 3D view using mol* of 1163 (AA BP:56) | ||||||||||
| ||||||||||
| PDB file (1172) >>>1172.pdbFusion protein BP residue: 46 CIF file (1172) >>>1172.cif | AFF1 | chr4 | 87967438 | + | KMT2A | chr11 | 118354897 | MAAQSSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKEKPP PVNKQENAGTLNILSTLSNGNSSKQKIPADGVHRIRVDFKEDCEAENVWE MGGLGILTSVPITPRVVCFLCASSGHVEFVYCQVCCEPFHKFCLEENERP LEDQLENWCCRRCKFCHVCGRQHQATKQLLECNKCRNSYHPECLGPNYPT KPTKKKKVWICTKCVRCKSCGSTTPGKGWDAQWSHDFSLCHDCAKLFAKG NFCPLCDKCYDDDDYESKMMQCGKCDRWVHSKCENLSDEMYEILSNLPES VAYTCVNCTERHPAEWRLALEKELQISLKQVLTALLNSRTTSHLLRYRQA AKPPDLNPETEESIPSRSSPEGPDPPVLTEVSKQDDQQPLDLEGVKRKMD QGNYTSVLEFSDDIVKIIQAAINSDGGQPEIKKANSMVKSFFIRQMERVF PWFSVKKSRFWEPNKVSSNSGMLPNAVLPPSLDHNYAQWQEREENSHTEQ PPLMKKIIPAPKPKGPGEPDSPTPLHPPTPPILSTDRSREDSPELNPPPG IEDNRQCALCLTYGDDSANDAGRLLYIGQNEWTHVNCALWSAEVFEDDDG SLKNVHMAVIRGKQLRCEFCQKPGATVGCCLTSCTSNYHFMCSRAKNCVF LDDKKVYCQRHRDLIKGEVVPENGFEVFRRVFVDFEGISLRRKFLNGLEP ENIHMMIGSMTIDCLGILNDLSDCEDKLFPIGYQCSRVYWSTTDARKRCV YTCKIVECRPPVVEPDINSTVEHDENRTIAHSPTSFTESSSKESQNTAEI ISPPSPDRPPHSQTSGSCYYHVISKVPRIRTPSYSPTQRSPGCRPLPSAG SPTPTTHEIVTVGDPLLSSGLRSIGSRRHSTSSLSPQRSKLRIMSPMRTG NTYSRNNVSSVSTTGTATDLESSAKVVDHVLGPLNSSTSLGQNTSTSSNL QRTVVTVGNKNSHLDGSSSSEMKQSSASDLVSKSSSLKGEKTKVLSSKSS EGSAHNVAYPGIPKLAPQVHNTTSRELNVSKIGSFAEPSSVSFSSKEALS FPHLHLRGQRNDRDQHTDSTQSANSSPDEDTEVKTLKLSGMSNRSSIINE HMGSSSRDRRQKGKKSCKETFKEKHSSKSFLEPGQVTTGEEGNLKPEFMD EVLTPEYMGQRPCNNVSSDKIGDKGLSMPGVPKAPPMQVEGSAKELQAPR KRTVKVTLTPLKMENESQSKNALKESSPASPLQIESTSPTEPISASENPG DGPVAQPSPNNTSCQDSQSNNYQNLPVQDRNLMLPDGPKPQEDGSFKRRY PRRSARARSNMFFGLTPLYGVRSYGEEDIPFYSSSTGKKRGKRSAEGQVD GADDLSTSDEDDLYYYNFTRTVISSGGEERLASHNLFREEEQCDLPKISQ LDGVDDGTESDTSVTATTRKSSQIPKRNGKENGTENLKIDRPEDAGEKEH VTKSSVGHKNEPKMDNCHSVSRVKTQGQDSLEAQLSSLESSRRVHTSTPS DKNLLDTYNTELLKSDSDNNNSDDCGNILPSDIMDFVLKNTPSMQALGES PESSSSELLNLGEGLGLDSNREKDMGLFEVFSQQLPTTEPVDSSVSSSIS AEEQFELPLELPSDLSVLTTRSPTVPSQNPSRLAVISDSGEKRVTITEKS VASSESDPALLSPGVDPTPEGHMTPDHFIQGHMDADHISSPPCGSVEQGH GNNQDLTRNSSTPGLQVPVSPTVPIQNQKYVPNSTDSPGPSQISNAAVQT TPPHLKPATEKLIVVNQNMQPLYVLQTLPNGVTQKIQLTSSVSSTPSVME TNTSVLGPMGGGLTLTTGLNPSLPTSQSLFPSASKGLLPMSHHQHLHSFP AATQSSFPPNISNPPSGLLIGVQPPPDPQLLVSESSQRTDLSTTVATPSS GLKKRPISRLQTRKNKKLAPSSTPSNIAPSDVVSNMTLINFTPSQLPNHP SLLDLGSLNTSSHRTVPNIIKRSKSSIMYFEPAPLLPQSVGGTAATAAGT STISQDTSHLTSGSVSGLASSSSVLNVVSMQTTTTPTSSASVPGHVTLTN PRLLGTPDIGSISNLLIKASQQSLGIQDQPVALPPSSGMFPQLGTSQTPS TAAITAASSICVLPSTQTTGITAASPSGEADEHYQLQHVNQLLASKTGIH SSQRDLDSASGPQVSNFTQTVDAPNSMGLEQNKALSSAVQASPTSPGGSP SSPSSGQRSASPSVPGPTKPKPKTKRFQLPLDKGNGKKHKVSHLRTSSSE AHIPDQETTSLTSGTGTPGAEAEQQDTASVEQSSQKECGQPAGQVAVLPE VQVTQNPANEQESAEPKTVEEEESNFSSPLMLWLQQEQKRKESITEKKPK KGLVFEISSDDGFQICAESIEDAWKSLTDKVQEARSNARLKQLSFAGVNG LRMLGILHDAVVFLIEQLSGAKHCRNYKFRFHKPEEANEPPLNPHGSARA EVHLRKSAFDMFNFLASKHRQPPEYNPNDEEEEEVQLKSARRATSMDLPM PMRFRHLKKTSKEAVGVYRSPIHGRGLFCKRNIDAGEMVIEYAGNVIRSI QTDKREKYYDSKGIGCYMFRIDDSEVVDATMHGNAARFINHSCEPNCYSR VINIDGQKHIVIFAMRKIYRGEELTYDYKFPIEDASNKLPCNCGAKKCRK | 2653 | |
| 3D view using mol* of 1172 (AA BP:46) | ||||||||||
| ||||||||||
| PDB file (1174) >>>1174.pdbFusion protein BP residue: 46 CIF file (1174) >>>1174.cif | AFF1 | chr4 | 87967438 | + | KMT2A | chr11 | 118354897 | MAAQSSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKEKPP PVNKQENAGTLNILSTLSNGNSSKQKIPADGVHRIRVDFKEDCEAENVWE MGGLGILTSVPITPRVVCFLCASSGHVEFVYCQVCCEPFHKFCLEENERP LEDQLENWCCRRCKFCHVCGRQHQATKQLLECNKCRNSYHPECLGPNYPT KPTKKKKVWICTKCVRCKSCGSTTPGKGWDAQWSHDFSLCHDCAKLFAKG NFCPLCDKCYDDDDYESKMMQCGKCDRWVHSKCENLSGTEDEMYEILSNL PESVAYTCVNCTERHPAEWRLALEKELQISLKQVLTALLNSRTTSHLLRY RQAAKPPDLNPETEESIPSRSSPEGPDPPVLTEVSKQDDQQPLDLEGVKR KMDQGNYTSVLEFSDDIVKIIQAAINSDGGQPEIKKANSMVKSFFIRQME RVFPWFSVKKSRFWEPNKVSSNSGMLPNAVLPPSLDHNYAQWQEREENSH TEQPPLMKKIIPAPKPKGPGEPDSPTPLHPPTPPILSTDRSREDSPELNP PPGIEDNRQCALCLTYGDDSANDAGRLLYIGQNEWTHVNCALWSAEVFED DDGSLKNVHMAVIRGKQLRCEFCQKPGATVGCCLTSCTSNYHFMCSRAKN CVFLDDKKVYCQRHRDLIKGEVVPENGFEVFRRVFVDFEGISLRRKFLNG LEPENIHMMIGSMTIDCLGILNDLSDCEDKLFPIGYQCSRVYWSTTDARK RCVYTCKIVECRPPVVEPDINSTVEHDENRTIAHSPTSFTESSSKESQNT AEIISPPSPDRPPHSQTSGSCYYHVISKVPRIRTPSYSPTQRSPGCRPLP SAGSPTPTTHEIVTVGDPLLSSGLRSIGSRRHSTSSLSPQRSKLRIMSPM RTGNTYSRNNVSSVSTTGTATDLESSAKVVDHVLGPLNSSTSLGQNTSTS SNLQRTVVTVGNKNSHLDGSSSSEMKQSSASDLVSKSSSLKGEKTKVLSS KSSEGSAHNVAYPGIPKLAPQVHNTTSRELNVSKIGSFAEPSSVSFSSKE ALSFPHLHLRGQRNDRDQHTDSTQSANSSPDEDTEVKTLKLSGMSNRSSI INEHMGSSSRDRRQKGKKSCKETFKEKHSSKSFLEPGQVTTGEEGNLKPE FMDEVLTPEYMGQRPCNNVSSDKIGDKGLSMPGVPKAPPMQVEGSAKELQ APRKRTVKVTLTPLKMENESQSKNALKESSPASPLQIESTSPTEPISASE NPGDGPVAQPSPNNTSCQDSQSNNYQNLPVQDRNLMLPDGPKPQEDGSFK RRYPRRSARARSNMFFGLTPLYGVRSYGEEDIPFYSSSTGKKRGKRSAEG QVDGADDLSTSDEDDLYYYNFTRTVISSGGEERLASHNLFREEEQCDLPK ISQLDGVDDGTESDTSVTATTRKSSQIPKRNGKENGTENLKIDRPEDAGE KEHVTKSSVGHKNEPKMDNCHSVSRVKTQGQDSLEAQLSSLESSRRVHTS TPSDKNLLDTYNTELLKSDSDNNNSDDCGNILPSDIMDFVLKNTPSMQAL GESPESSSSELLNLGEGLGLDSNREKDMGLFEVFSQQLPTTEPVDSSVSS SISAEEQFELPLELPSDLSVLTTRSPTVPSQNPSRLAVISDSGEKRVTIT EKSVASSESDPALLSPGVDPTPEGHMTPDHFIQGHMDADHISSPPCGSVE QGHGNNQDLTRNSSTPGLQVPVSPTVPIQNQKYVPNSTDSPGPSQISNAA VQTTPPHLKPATEKLIVVNQNMQPLYVLQTLPNGVTQKIQLTSSVSSTPS VMETNTSVLGPMGGGLTLTTGLNPSLPTSQSLFPSASKGLLPMSHHQHLH SFPAATQSSFPPNISNPPSGLLIGVQPPPDPQLLVSESSQRTDLSTTVAT PSSGLKKRPISRLQTRKNKKLAPSSTPSNIAPSDVVSNMTLINFTPSQLP NHPSLLDLGSLNTSSHRTVPNIIKRSKSSIMYFEPAPLLPQSVGGTAATA AGTSTISQDTSHLTSGSVSGLASSSSVLNVVSMQTTTTPTSSASVPGHVT LTNPRLLGTPDIGSISNLLIKASQQSLGIQDQPVALPPSSGMFPQLGTSQ TPSTAAITAASSICVLPSTQTTGITAASPSGEADEHYQLQHVNQLLASKT GIHSSQRDLDSASGPQVSNFTQTVDAPNSMGLEQNKALSSAVQASPTSPG GSPSSPSSGQRSASPSVPGPTKPKPKTKRFQLPLDKGNGKKHKVSHLRTS SSEAHIPDQETTSLTSGTGTPGAEAEQQDTASVEQSSQKECGQPAGQVAV LPEVQVTQNPANEQESAEPKTVEEEESNFSSPLMLWLQQEQKRKESITEK KPKKGLVFEISSDDGFQICAESIEDAWKSLTDKVQEARSNARLKQLSFAG VNGLRMLGILHDAVVFLIEQLSGAKHCRNYKFRFHKPEEANEPPLNPHGS ARAEVHLRKSAFDMFNFLASKHRQPPEYNPNDEEEEEVQLKSARRATSMD LPMPMRFRHLKKTSKEAVGVYRSPIHGRGLFCKRNIDAGEMVIEYAGNVI RSIQTDKREKYYDSKGIGCYMFRIDDSEVVDATMHGNAARFINHSCEPNC YSRVINIDGQKHIVIFAMRKIYRGEELTYDYKFPIEDASNKLPCNCGAKK | 2656 | |
| 3D view using mol* of 1174 (AA BP:46) | ||||||||||
| ||||||||||
| PDB file (1177) >>>1177.pdbFusion protein BP residue: 56 CIF file (1177) >>>1177.cif | AFF1 | chr4 | 87967438 | + | KMT2A | chr11 | 118354897 | METMAFTERVNSSGNSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPL FGEPYKEKPPPVNKQENAGTLNILSTLSNGNSSKQKIPADGVHRIRVDFK EDCEAENVWEMGGLGILTSVPITPRVVCFLCASSGHVEFVYCQVCCEPFH KFCLEENERPLEDQLENWCCRRCKFCHVCGRQHQATKQLLECNKCRNSYH PECLGPNYPTKPTKKKKVWICTKCVRCKSCGSTTPGKGWDAQWSHDFSLC HDCAKLFAKGNFCPLCDKCYDDDDYESKMMQCGKCDRWVHSKCENLSDEM YEILSNLPESVAYTCVNCTERHPAEWRLALEKELQISLKQVLTALLNSRT TSHLLRYRQAAKPPDLNPETEESIPSRSSPEGPDPPVLTEVSKQDDQQPL DLEGVKRKMDQGNYTSVLEFSDDIVKIIQAAINSDGGQPEIKKANSMVKS FFIRQMERVFPWFSVKKSRFWEPNKVSSNSGMLPNAVLPPSLDHNYAQWQ EREENSHTEQPPLMKKIIPAPKPKGPGEPDSPTPLHPPTPPILSTDRSRE DSPELNPPPGIEDNRQCALCLTYGDDSANDAGRLLYIGQNEWTHVNCALW SAEVFEDDDGSLKNVHMAVIRGKQLRCEFCQKPGATVGCCLTSCTSNYHF MCSRAKNCVFLDDKKVYCQRHRDLIKGEVVPENGFEVFRRVFVDFEGISL RRKFLNGLEPENIHMMIGSMTIDCLGILNDLSDCEDKLFPIGYQCSRVYW STTDARKRCVYTCKIVECRPPVVEPDINSTVEHDENRTIAHSPTSFTESS SKESQNTAEIISPPSPDRPPHSQTSGSCYYHVISKVPRIRTPSYSPTQRS PGCRPLPSAGSPTPTTHEIVTVGDPLLSSGLRSIGSRRHSTSSLSPQRSK LRIMSPMRTGNTYSRNNVSSVSTTGTATDLESSAKVVDHVLGPLNSSTSL GQNTSTSSNLQRTVVTVGNKNSHLDGSSSSEMKQSSASDLVSKSSSLKGE KTKVLSSKSSEGSAHNVAYPGIPKLAPQVHNTTSRELNVSKIGSFAEPSS VSFSSKEALSFPHLHLRGQRNDRDQHTDSTQSANSSPDEDTEVKTLKLSG MSNRSSIINEHMGSSSRDRRQKGKKSCKETFKEKHSSKSFLEPGQVTTGE EGNLKPEFMDEVLTPEYMGQRPCNNVSSDKIGDKGLSMPGVPKAPPMQVE GSAKELQAPRKRTVKVTLTPLKMENESQSKNALKESSPASPLQIESTSPT EPISASENPGDGPVAQPSPNNTSCQDSQSNNYQNLPVQDRNLMLPDGPKP QEDGSFKRRYPRRSARARSNMFFGLTPLYGVRSYGEEDIPFYSSSTGKKR GKRSAEGQVDGADDLSTSDEDDLYYYNFTRTVISSGGEERLASHNLFREE EQCDLPKISQLDGVDDGTESDTSVTATTRKSSQIPKRNGKENGTENLKID RPEDAGEKEHVTKSSVGHKNEPKMDNCHSVSRVKTQGQDSLEAQLSSLES SRRVHTSTPSDKNLLDTYNTELLKSDSDNNNSDDCGNILPSDIMDFVLKN TPSMQALGESPESSSSELLNLGEGLGLDSNREKDMGLFEVFSQQLPTTEP VDSSVSSSISAEEQFELPLELPSDLSVLTTRSPTVPSQNPSRLAVISDSG EKRVTITEKSVASSESDPALLSPGVDPTPEGHMTPDHFIQGHMDADHISS PPCGSVEQGHGNNQDLTRNSSTPGLQVPVSPTVPIQNQKYVPNSTDSPGP SQISNAAVQTTPPHLKPATEKLIVVNQNMQPLYVLQTLPNGVTQKIQLTS SVSSTPSVMETNTSVLGPMGGGLTLTTGLNPSLPTSQSLFPSASKGLLPM SHHQHLHSFPAATQSSFPPNISNPPSGLLIGVQPPPDPQLLVSESSQRTD LSTTVATPSSGLKKRPISRLQTRKNKKLAPSSTPSNIAPSDVVSNMTLIN FTPSQLPNHPSLLDLGSLNTSSHRTVPNIIKRSKSSIMYFEPAPLLPQSV GGTAATAAGTSTISQDTSHLTSGSVSGLASSSSVLNVVSMQTTTTPTSSA SVPGHVTLTNPRLLGTPDIGSISNLLIKASQQSLGIQDQPVALPPSSGMF PQLGTSQTPSTAAITAASSICVLPSTQTTGITAASPSGEADEHYQLQHVN QLLASKTGIHSSQRDLDSASGPQVSNFTQTVDAPNSMGLEQNKALSSAVQ ASPTSPGGSPSSPSSGQRSASPSVPGPTKPKPKTKRFQLPLDKGNGKKHK VSHLRTSSSEAHIPDQETTSLTSGTGTPGAEAEQQDTASVEQSSQKECGQ PAGQVAVLPEVQVTQNPANEQESAEPKTVEEEESNFSSPLMLWLQQEQKR KESITEKKPKKGLVFEISSDDGFQICAESIEDAWKSLTDKVQEARSNARL KQLSFAGVNGLRMLGILHDAVVFLIEQLSGAKHCRNYKFRFHKPEEANEP PLNPHGSARAEVHLRKSAFDMFNFLASKHRQPPEYNPNDEEEEEVQLKSA RRATSMDLPMPMRFRHLKKTSKEAVGVYRSPIHGRGLFCKRNIDAGEMVI EYAGNVIRSIQTDKREKYYDSKGIGCYMFRIDDSEVVDATMHGNAARFIN HSCEPNCYSRVINIDGQKHIVIFAMRKIYRGEELTYDYKFPIEDASNKLP | 2663 | |
| 3D view using mol* of 1177 (AA BP:56) | ||||||||||
| ||||||||||
| PDB file (1180) >>>1180.pdbFusion protein BP residue: 56 CIF file (1180) >>>1180.cif | AFF1 | chr4 | 87967438 | + | KMT2A | chr11 | 118354897 | METMAFTERVNSSGNSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPL FGEPYKEKPPPVNKQENAGTLNILSTLSNGNSSKQKIPADGVHRIRVDFK EDCEAENVWEMGGLGILTSVPITPRVVCFLCASSGHVEFVYCQVCCEPFH KFCLEENERPLEDQLENWCCRRCKFCHVCGRQHQATKQLLECNKCRNSYH PECLGPNYPTKPTKKKKVWICTKCVRCKSCGSTTPGKGWDAQWSHDFSLC HDCAKLFAKGNFCPLCDKCYDDDDYESKMMQCGKCDRWVHSKCENLSGTE DEMYEILSNLPESVAYTCVNCTERHPAEWRLALEKELQISLKQVLTALLN SRTTSHLLRYRQAAKPPDLNPETEESIPSRSSPEGPDPPVLTEVSKQDDQ QPLDLEGVKRKMDQGNYTSVLEFSDDIVKIIQAAINSDGGQPEIKKANSM VKSFFIRQMERVFPWFSVKKSRFWEPNKVSSNSGMLPNAVLPPSLDHNYA QWQEREENSHTEQPPLMKKIIPAPKPKGPGEPDSPTPLHPPTPPILSTDR SREDSPELNPPPGIEDNRQCALCLTYGDDSANDAGRLLYIGQNEWTHVNC ALWSAEVFEDDDGSLKNVHMAVIRGKQLRCEFCQKPGATVGCCLTSCTSN YHFMCSRAKNCVFLDDKKVYCQRHRDLIKGEVVPENGFEVFRRVFVDFEG ISLRRKFLNGLEPENIHMMIGSMTIDCLGILNDLSDCEDKLFPIGYQCSR VYWSTTDARKRCVYTCKIVECRPPVVEPDINSTVEHDENRTIAHSPTSFT ESSSKESQNTAEIISPPSPDRPPHSQTSGSCYYHVISKVPRIRTPSYSPT QRSPGCRPLPSAGSPTPTTHEIVTVGDPLLSSGLRSIGSRRHSTSSLSPQ RSKLRIMSPMRTGNTYSRNNVSSVSTTGTATDLESSAKVVDHVLGPLNSS TSLGQNTSTSSNLQRTVVTVGNKNSHLDGSSSSEMKQSSASDLVSKSSSL KGEKTKVLSSKSSEGSAHNVAYPGIPKLAPQVHNTTSRELNVSKIGSFAE PSSVSFSSKEALSFPHLHLRGQRNDRDQHTDSTQSANSSPDEDTEVKTLK LSGMSNRSSIINEHMGSSSRDRRQKGKKSCKETFKEKHSSKSFLEPGQVT TGEEGNLKPEFMDEVLTPEYMGQRPCNNVSSDKIGDKGLSMPGVPKAPPM QVEGSAKELQAPRKRTVKVTLTPLKMENESQSKNALKESSPASPLQIEST SPTEPISASENPGDGPVAQPSPNNTSCQDSQSNNYQNLPVQDRNLMLPDG PKPQEDGSFKRRYPRRSARARSNMFFGLTPLYGVRSYGEEDIPFYSSSTG KKRGKRSAEGQVDGADDLSTSDEDDLYYYNFTRTVISSGGEERLASHNLF REEEQCDLPKISQLDGVDDGTESDTSVTATTRKSSQIPKRNGKENGTENL KIDRPEDAGEKEHVTKSSVGHKNEPKMDNCHSVSRVKTQGQDSLEAQLSS LESSRRVHTSTPSDKNLLDTYNTELLKSDSDNNNSDDCGNILPSDIMDFV LKNTPSMQALGESPESSSSELLNLGEGLGLDSNREKDMGLFEVFSQQLPT TEPVDSSVSSSISAEEQFELPLELPSDLSVLTTRSPTVPSQNPSRLAVIS DSGEKRVTITEKSVASSESDPALLSPGVDPTPEGHMTPDHFIQGHMDADH ISSPPCGSVEQGHGNNQDLTRNSSTPGLQVPVSPTVPIQNQKYVPNSTDS PGPSQISNAAVQTTPPHLKPATEKLIVVNQNMQPLYVLQTLPNGVTQKIQ LTSSVSSTPSVMETNTSVLGPMGGGLTLTTGLNPSLPTSQSLFPSASKGL LPMSHHQHLHSFPAATQSSFPPNISNPPSGLLIGVQPPPDPQLLVSESSQ RTDLSTTVATPSSGLKKRPISRLQTRKNKKLAPSSTPSNIAPSDVVSNMT LINFTPSQLPNHPSLLDLGSLNTSSHRTVPNIIKRSKSSIMYFEPAPLLP QSVGGTAATAAGTSTISQDTSHLTSGSVSGLASSSSVLNVVSMQTTTTPT SSASVPGHVTLTNPRLLGTPDIGSISNLLIKASQQSLGIQDQPVALPPSS GMFPQLGTSQTPSTAAITAASSICVLPSTQTTGITAASPSGEADEHYQLQ HVNQLLASKTGIHSSQRDLDSASGPQVSNFTQTVDAPNSMGLEQNKALSS AVQASPTSPGGSPSSPSSGQRSASPSVPGPTKPKPKTKRFQLPLDKGNGK KHKVSHLRTSSSEAHIPDQETTSLTSGTGTPGAEAEQQDTASVEQSSQKE CGQPAGQVAVLPEVQVTQNPANEQESAEPKTVEEEESNFSSPLMLWLQQE QKRKESITEKKPKKGLVFEISSDDGFQICAESIEDAWKSLTDKVQEARSN ARLKQLSFAGVNGLRMLGILHDAVVFLIEQLSGAKHCRNYKFRFHKPEEA NEPPLNPHGSARAEVHLRKSAFDMFNFLASKHRQPPEYNPNDEEEEEVQL KSARRATSMDLPMPMRFRHLKKTSKEAVGVYRSPIHGRGLFCKRNIDAGE MVIEYAGNVIRSIQTDKREKYYDSKGIGCYMFRIDDSEVVDATMHGNAAR FINHSCEPNCYSRVINIDGQKHIVIFAMRKIYRGEELTYDYKFPIEDASN | 2666 | |
| 3D view using mol* of 1180 (AA BP:56) | ||||||||||
| ||||||||||
| PDB file (1226) >>>1226.pdbFusion protein BP residue: 346 CIF file (1226) >>>1226.cif | AFF1 | chr4 | 87968746 | + | KMT2A | chr11 | 118354897 | MAAQSSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKTAKG DELSSRIQNMLGNYEEVKEFLSTKSHTHRLDASENRLGKPKYPLIPDKGS SIPSSSFHTSVHHQSIHTPASGPLSVGNISHNPKMAQPRTEPMPSLHAKS CGPPDSQHLTQDRLGQEGFGSSHHKKGDRRADGDHCASVTDSAPERELSP LISLPSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNNSKGYCPAKSPKDLA VKVHDKETPQDSLVAPAQPPSQTFPPPSLPSKSVAMQQKPTAYVRPMDGQ DQAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEEKPP PVNKQENAGTLNILSTLSNGNSSKQKIPADGVHRIRVDFKFVYCQVCCEP FHKFCLEENERPLEDQLENWCCRRCKFCHVCGRQHQATKQLLECNKCRNS YHPECLGPNYPTKPTKKKKVWICTKCVRCKSCGSTTPGKGWDAQWSHDFS LCHDCAKLFAKGNFCPLCDKCYDDDDYESKMMQCGKCDRWVHSKCENLSD EMYEILSNLPESVAYTCVNCTERHPAEWRLALEKELQISLKQVLTALLNS RTTSHLLRYRQAAKPPDLNPETEESIPSRSSPEGPDPPVLTEVSKQDDQQ PLDLEGVKRKMDQGNYTSVLEFSDDIVKIIQAAINSDGGQPEIKKANSMV KSFFIRQMERVFPWFSVKKSRFWEPNKVSSNSGMLPNAVLPPSLDHNYAQ WQEREENSHTEQPPLMKKIIPAPKPKGPGEPDSPTPLHPPTPPILSTDRS REDSPELNPPPGIEDNRQCALCLTYGDDSANDAGRLLYIGQNEWTHVNCA LWSAEVFEDDDGSLKNVHMAVIRGKQLRCEFCQKPGATVGCCLTSCTSNY HFMCSRAKNCVFLDDKKVYCQRHRDLIKGEVVPENGFEVFRRVFVDFEGI SLRRKFLNGLEPENIHMMIGSMTIDCLGILNDLSDCEDKLFPIGYQCSRV YWSTTDARKRCVYTCKIVECRPPVVEPDINSTVEHDENRTIAHSPTSFTE SSSKESQNTAEIISPPSPDRPPHSQTSGSCYYHVISKVPRIRTPSYSPTQ RSPGCRPLPSAGSPTPTTHEIVTVGDPLLSSGLRSIGSRRHSTSSLSPQR SKLRIMSPMRTGNTYSRNNVSSVSTTGTATDLESSAKVVDHVLGPLNSST SLGQNTSTSSNLQRTVVTVGNKNSHLDGSSSSEMKQSSASDLVSKSSSLK GEKTKVLSSKSSEGSAHNVAYPGIPKLAPQVHNTTSRELNVSKIGSFAEP SSVSFSSKEALSFPHLHLRGQRNDRDQHTDSTQSANSSPDEDTEVKTLKL SGMSNRSSIINEHMGSSSRDRRQKGKKSCKETFKEKHSSKSFLEPGQVTT GEEGNLKPEFMDEVLTPEYMGQRPCNNVSSDKIGDKGLSMPGVPKAPPMQ VEGSAKELQAPRKRTVKVTLTPLKMENESQSKNALKESSPASPLQIESTS PTEPISASENPGDGPVAQPSPNNTSCQDSQSNNYQNLPVQDRNLMLPDGP KPQEDGSFKRRYPRRSARARSNMFFGLTPLYGVRSYGEEDIPFYSSSTGK KRGKRSAEGQVDGADDLSTSDEDDLYYYNFTRTVISSGGEERLASHNLFR EEEQCDLPKISQLDGVDDGTESDTSVTATTRKSSQIPKRNGKENGTENLK IDRPEDAGEKEHVTKSSVGHKNEPKMDNCHSVSRVKTQGQDSLEAQLSSL ESSRRVHTSTPSDKNLLDTYNTELLKSDSDNNNSDDCGNILPSDIMDFVL KNTPSMQALGESPESSSSELLNLGEGLGLDSNREKDMGLFEVFSQQLPTT EPVDSSVSSSISAEEQFELPLELPSDLSVLTTRSPTVPSQNPSRLAVISD SGEKRVTITEKSVASSESDPALLSPGVDPTPEGHMTPDHFIQGHMDADHI SSPPCGSVEQGHGNNQDLTRNSSTPGLQVPVSPTVPIQNQKYVPNSTDSP GPSQISNAAVQTTPPHLKPATEKLIVVNQNMQPLYVLQTLPNGVTQKIQL TSSVSSTPSVMETNTSVLGPMGGGLTLTTGLNPSLPTSQSLFPSASKGLL PMSHHQHLHSFPAATQSSFPPNISNPPSGLLIGVQPPPDPQLLVSESSQR TDLSTTVATPSSGLKKRPISRLQTRKNKKLAPSSTPSNIAPSDVVSNMTL INFTPSQLPNHPSLLDLGSLNTSSHRTVPNIIKRSKSSIMYFEPAPLLPQ SVGGTAATAAGTSTISQDTSHLTSGSVSGLASSSSVLNVVSMQTTTTPTS SASVPGHVTLTNPRLLGTPDIGSISNLLIKASQQSLGIQDQPVALPPSSG MFPQLGTSQTPSTAAITAASSICVLPSTQTTGITAASPSGEADEHYQLQH VNQLLASKTGIHSSQRDLDSASGPQVSNFTQTVDAPNSMGLEQNKALSSA VQASPTSPGGSPSSPSSGQRSASPSVPGPTKPKPKTKRFQLPLDKGNGKK HKVSHLRTSSSEAHIPDQETTSLTSGTGTPGAEAEQQDTASVEQSSQKEC GQPAGQVAVLPEVQVTQNPANEQESAEPKTVEEEESNFSSPLMLWLQQEQ KRKESITEKKPKKGLVFEISSDDGFQICAESIEDAWKSLTDKVQEARSNA RLKQLSFAGVNGLRMLGILHDAVVFLIEQLSGAKHCRNYKFRFHKPEEAN EPPLNPHGSARAEVHLRKSAFDMFNFLASKHRQPPEYNPNDEEEEEVQLK SARRATSMDLPMPMRFRHLKKTSKEAVGVYRSPIHGRGLFCKRNIDAGEM VIEYAGNVIRSIQTDKREKYYDSKGIGCYMFRIDDSEVVDATMHGNAARF INHSCEPNCYSRVINIDGQKHIVIFAMRKIYRGEELTYDYKFPIEDASNK | 2915 | |
| 3D view using mol* of 1226 (AA BP:346) | ||||||||||
| ||||||||||
| PDB file (1228) | AFF1 | chr4 | 87968746 | + | KMT2A | chr11 | 118354897 | METMAFTERVNSSGNSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPL FGEPYKTAKGDELSSRIQNMLGNYEEVKEFLSTKSHTHRLDASENRLGKP KYPLIPDKGSSIPSSSFHTSVHHQSIHTPASGPLSVGNISHNPKMAQPRT EPMPSLHAKSCGPPDSQHLTQDRLGQEGFGSSHHKKGDRRADGDHCASVT DSAPERELSPLISLPSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNNSKGY CPAKSPKDLAVKVHDKETPQDSLVAPAQPPSQTFPPPSLPSKSVAMQQKP TAYVRPMDGQDQAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKM PSQSVEEKPPPVNKQENAGTLNILSTLSNGNSSKQKIPADGVHRIRVDFK FVYCQVCCEPFHKFCLEENERPLEDQLENWCCRRCKFCHVCGRQHQATKQ LLECNKCRNSYHPECLGPNYPTKPTKKKKVWICTKCVRCKSCGSTTPGKG WDAQWSHDFSLCHDCAKLFAKGNFCPLCDKCYDDDDYESKMMQCGKCDRW VHSKCENLSDEMYEILSNLPESVAYTCVNCTERHPAEWRLALEKELQISL KQVLTALLNSRTTSHLLRYRQAAKPPDLNPETEESIPSRSSPEGPDPPVL TEVSKQDDQQPLDLEGVKRKMDQGNYTSVLEFSDDIVKIIQAAINSDGGQ PEIKKANSMVKSFFIRQMERVFPWFSVKKSRFWEPNKVSSNSGMLPNAVL PPSLDHNYAQWQEREENSHTEQPPLMKKIIPAPKPKGPGEPDSPTPLHPP TPPILSTDRSREDSPELNPPPGIEDNRQCALCLTYGDDSANDAGRLLYIG QNEWTHVNCALWSAEVFEDDDGSLKNVHMAVIRGKQLRCEFCQKPGATVG CCLTSCTSNYHFMCSRAKNCVFLDDKKVYCQRHRDLIKGEVVPENGFEVF RRVFVDFEGISLRRKFLNGLEPENIHMMIGSMTIDCLGILNDLSDCEDKL FPIGYQCSRVYWSTTDARKRCVYTCKIVECRPPVVEPDINSTVEHDENRT IAHSPTSFTESSSKESQNTAEIISPPSPDRPPHSQTSGSCYYHVISKVPR IRTPSYSPTQRSPGCRPLPSAGSPTPTTHEIVTVGDPLLSSGLRSIGSRR HSTSSLSPQRSKLRIMSPMRTGNTYSRNNVSSVSTTGTATDLESSAKVVD HVLGPLNSSTSLGQNTSTSSNLQRTVVTVGNKNSHLDGSSSSEMKQSSAS DLVSKSSSLKGEKTKVLSSKSSEGSAHNVAYPGIPKLAPQVHNTTSRELN VSKIGSFAEPSSVSFSSKEALSFPHLHLRGQRNDRDQHTDSTQSANSSPD EDTEVKTLKLSGMSNRSSIINEHMGSSSRDRRQKGKKSCKETFKEKHSSK SFLEPGQVTTGEEGNLKPEFMDEVLTPEYMGQRPCNNVSSDKIGDKGLSM PGVPKAPPMQVEGSAKELQAPRKRTVKVTLTPLKMENESQSKNALKESSP ASPLQIESTSPTEPISASENPGDGPVAQPSPNNTSCQDSQSNNYQNLPVQ DRNLMLPDGPKPQEDGSFKRRYPRRSARARSNMFFGLTPLYGVRSYGEED IPFYSSSTGKKRGKRSAEGQVDGADDLSTSDEDDLYYYNFTRTVISSGGE ERLASHNLFREEEQCDLPKISQLDGVDDGTESDTSVTATTRKSSQIPKRN GKENGTENLKIDRPEDAGEKEHVTKSSVGHKNEPKMDNCHSVSRVKTQGQ DSLEAQLSSLESSRRVHTSTPSDKNLLDTYNTELLKSDSDNNNSDDCGNI LPSDIMDFVLKNTPSMQALGESPESSSSELLNLGEGLGLDSNREKDMGLF EVFSQQLPTTEPVDSSVSSSISAEEQFELPLELPSDLSVLTTRSPTVPSQ NPSRLAVISDSGEKRVTITEKSVASSESDPALLSPGVDPTPEGHMTPDHF IQGHMDADHISSPPCGSVEQGHGNNQDLTRNSSTPGLQVPVSPTVPIQNQ KYVPNSTDSPGPSQISNAAVQTTPPHLKPATEKLIVVNQNMQPLYVLQTL PNGVTQKIQLTSSVSSTPSVMETNTSVLGPMGGGLTLTTGLNPSLPTSQS LFPSASKGLLPMSHHQHLHSFPAATQSSFPPNISNPPSGLLIGVQPPPDP QLLVSESSQRTDLSTTVATPSSGLKKRPISRLQTRKNKKLAPSSTPSNIA PSDVVSNMTLINFTPSQLPNHPSLLDLGSLNTSSHRTVPNIIKRSKSSIM YFEPAPLLPQSVGGTAATAAGTSTISQDTSHLTSGSVSGLASSSSVLNVV SMQTTTTPTSSASVPGHVTLTNPRLLGTPDIGSISNLLIKASQQSLGIQD QPVALPPSSGMFPQLGTSQTPSTAAITAASSICVLPSTQTTGITAASPSG EADEHYQLQHVNQLLASKTGIHSSQRDLDSASGPQVSNFTQTVDAPNSMG LEQNKALSSAVQASPTSPGGSPSSPSSGQRSASPSVPGPTKPKPKTKRFQ LPLDKGNGKKHKVSHLRTSSSEAHIPDQETTSLTSGTGTPGAEAEQQDTA SVEQSSQKECGQPAGQVAVLPEVQVTQNPANEQESAEPKTVEEEESNFSS PLMLWLQQEQKRKESITEKKPKKGLVFEISSDDGFQICAESIEDAWKSLT DKVQEARSNARLKQLSFAGVNGLRMLGILHDAVVFLIEQLSGAKHCRNYK FRFHKPEEANEPPLNPHGSARAEVHLRKSAFDMFNFLASKHRQPPEYNPN DEEEEEVQLKSARRATSMDLPMPMRFRHLKKTSKEAVGVYRSPIHGRGLF CKRNIDAGEMVIEYAGNVIRSIQTDKREKYYDSKGIGCYMFRIDDSEVVD ATMHGNAARFINHSCEPNCYSRVINIDGQKHIVIFAMRKIYRGEELTYDY | 2925 | |
| PDB file (1238) | AFF1 | chr4 | 87968746 | + | KMT2A | chr11 | 118354897 | MAAQSSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKTAKG DELSSRIQNMLGNYEEVKEFLSTKSHTHRLDASENRLGKPKYPLIPDKGS SIPSSSFHTSVHHQSIHTPASGPLSVGNISHNPKMAQPRTEPMPSLHAKS CGPPDSQHLTQDRLGQEGFGSSHHKKGDRRADGDHCASVTDSAPERELSP LISLPSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNNSKGYCPAKSPKDLA VKVHDKETPQDSLVAPAQPPSQTFPPPSLPSKSVAMQQKPTAYVRPMDGQ DQAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEEKPP PVNKQENAGTLNILSTLSNGNSSKQKIPADGVHRIRVDFKEDCEAENVWE MGGLGILTSVPITPRVVCFLCASSGHVEFVYCQVCCEPFHKFCLEENERP LEDQLENWCCRRCKFCHVCGRQHQATKQLLECNKCRNSYHPECLGPNYPT KPTKKKKVWICTKCVRCKSCGSTTPGKGWDAQWSHDFSLCHDCAKLFAKG NFCPLCDKCYDDDDYESKMMQCGKCDRWVHSKCENLSDEMYEILSNLPES VAYTCVNCTERHPAEWRLALEKELQISLKQVLTALLNSRTTSHLLRYRQA AKPPDLNPETEESIPSRSSPEGPDPPVLTEVSKQDDQQPLDLEGVKRKMD QGNYTSVLEFSDDIVKIIQAAINSDGGQPEIKKANSMVKSFFIRQMERVF PWFSVKKSRFWEPNKVSSNSGMLPNAVLPPSLDHNYAQWQEREENSHTEQ PPLMKKIIPAPKPKGPGEPDSPTPLHPPTPPILSTDRSREDSPELNPPPG IEDNRQCALCLTYGDDSANDAGRLLYIGQNEWTHVNCALWSAEVFEDDDG SLKNVHMAVIRGKQLRCEFCQKPGATVGCCLTSCTSNYHFMCSRAKNCVF LDDKKVYCQRHRDLIKGEVVPENGFEVFRRVFVDFEGISLRRKFLNGLEP ENIHMMIGSMTIDCLGILNDLSDCEDKLFPIGYQCSRVYWSTTDARKRCV YTCKIVECRPPVVEPDINSTVEHDENRTIAHSPTSFTESSSKESQNTAEI ISPPSPDRPPHSQTSGSCYYHVISKVPRIRTPSYSPTQRSPGCRPLPSAG SPTPTTHEIVTVGDPLLSSGLRSIGSRRHSTSSLSPQRSKLRIMSPMRTG NTYSRNNVSSVSTTGTATDLESSAKVVDHVLGPLNSSTSLGQNTSTSSNL QRTVVTVGNKNSHLDGSSSSEMKQSSASDLVSKSSSLKGEKTKVLSSKSS EGSAHNVAYPGIPKLAPQVHNTTSRELNVSKIGSFAEPSSVSFSSKEALS FPHLHLRGQRNDRDQHTDSTQSANSSPDEDTEVKTLKLSGMSNRSSIINE HMGSSSRDRRQKGKKSCKETFKEKHSSKSFLEPGQVTTGEEGNLKPEFMD EVLTPEYMGQRPCNNVSSDKIGDKGLSMPGVPKAPPMQVEGSAKELQAPR KRTVKVTLTPLKMENESQSKNALKESSPASPLQIESTSPTEPISASENPG DGPVAQPSPNNTSCQDSQSNNYQNLPVQDRNLMLPDGPKPQEDGSFKRRY PRRSARARSNMFFGLTPLYGVRSYGEEDIPFYSSSTGKKRGKRSAEGQVD GADDLSTSDEDDLYYYNFTRTVISSGGEERLASHNLFREEEQCDLPKISQ LDGVDDGTESDTSVTATTRKSSQIPKRNGKENGTENLKIDRPEDAGEKEH VTKSSVGHKNEPKMDNCHSVSRVKTQGQDSLEAQLSSLESSRRVHTSTPS DKNLLDTYNTELLKSDSDNNNSDDCGNILPSDIMDFVLKNTPSMQALGES PESSSSELLNLGEGLGLDSNREKDMGLFEVFSQQLPTTEPVDSSVSSSIS AEEQFELPLELPSDLSVLTTRSPTVPSQNPSRLAVISDSGEKRVTITEKS VASSESDPALLSPGVDPTPEGHMTPDHFIQGHMDADHISSPPCGSVEQGH GNNQDLTRNSSTPGLQVPVSPTVPIQNQKYVPNSTDSPGPSQISNAAVQT TPPHLKPATEKLIVVNQNMQPLYVLQTLPNGVTQKIQLTSSVSSTPSVME TNTSVLGPMGGGLTLTTGLNPSLPTSQSLFPSASKGLLPMSHHQHLHSFP AATQSSFPPNISNPPSGLLIGVQPPPDPQLLVSESSQRTDLSTTVATPSS GLKKRPISRLQTRKNKKLAPSSTPSNIAPSDVVSNMTLINFTPSQLPNHP SLLDLGSLNTSSHRTVPNIIKRSKSSIMYFEPAPLLPQSVGGTAATAAGT STISQDTSHLTSGSVSGLASSSSVLNVVSMQTTTTPTSSASVPGHVTLTN PRLLGTPDIGSISNLLIKASQQSLGIQDQPVALPPSSGMFPQLGTSQTPS TAAITAASSICVLPSTQTTGITAASPSGEADEHYQLQHVNQLLASKTGIH SSQRDLDSASGPQVSNFTQTVDAPNSMGLEQNKALSSAVQASPTSPGGSP SSPSSGQRSASPSVPGPTKPKPKTKRFQLPLDKGNGKKHKVSHLRTSSSE AHIPDQETTSLTSGTGTPGAEAEQQDTASVEQSSQKECGQPAGQVAVLPE VQVTQNPANEQESAEPKTVEEEESNFSSPLMLWLQQEQKRKESITEKKPK KGLVFEISSDDGFQICAESIEDAWKSLTDKVQEARSNARLKQLSFAGVNG LRMLGILHDAVVFLIEQLSGAKHCRNYKFRFHKPEEANEPPLNPHGSARA EVHLRKSAFDMFNFLASKHRQPPEYNPNDEEEEEVQLKSARRATSMDLPM PMRFRHLKKTSKEAVGVYRSPIHGRGLFCKRNIDAGEMVIEYAGNVIRSI QTDKREKYYDSKGIGCYMFRIDDSEVVDATMHGNAARFINHSCEPNCYSR VINIDGQKHIVIFAMRKIYRGEELTYDYKFPIEDASNKLPCNCGAKKCRK | 2953 | |
| PDB file (1239) | AFF1 | chr4 | 87968746 | + | KMT2A | chr11 | 118354897 | MAAQSSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKTAKG DELSSRIQNMLGNYEEVKEFLSTKSHTHRLDASENRLGKPKYPLIPDKGS SIPSSSFHTSVHHQSIHTPASGPLSVGNISHNPKMAQPRTEPMPSLHAKS CGPPDSQHLTQDRLGQEGFGSSHHKKGDRRADGDHCASVTDSAPERELSP LISLPSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNNSKGYCPAKSPKDLA VKVHDKETPQDSLVAPAQPPSQTFPPPSLPSKSVAMQQKPTAYVRPMDGQ DQAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEEKPP PVNKQENAGTLNILSTLSNGNSSKQKIPADGVHRIRVDFKEDCEAENVWE MGGLGILTSVPITPRVVCFLCASSGHVEFVYCQVCCEPFHKFCLEENERP LEDQLENWCCRRCKFCHVCGRQHQATKQLLECNKCRNSYHPECLGPNYPT KPTKKKKVWICTKCVRCKSCGSTTPGKGWDAQWSHDFSLCHDCAKLFAKG NFCPLCDKCYDDDDYESKMMQCGKCDRWVHSKCENLSGTEDEMYEILSNL PESVAYTCVNCTERHPAEWRLALEKELQISLKQVLTALLNSRTTSHLLRY RQAAKPPDLNPETEESIPSRSSPEGPDPPVLTEVSKQDDQQPLDLEGVKR KMDQGNYTSVLEFSDDIVKIIQAAINSDGGQPEIKKANSMVKSFFIRQME RVFPWFSVKKSRFWEPNKVSSNSGMLPNAVLPPSLDHNYAQWQEREENSH TEQPPLMKKIIPAPKPKGPGEPDSPTPLHPPTPPILSTDRSREDSPELNP PPGIEDNRQCALCLTYGDDSANDAGRLLYIGQNEWTHVNCALWSAEVFED DDGSLKNVHMAVIRGKQLRCEFCQKPGATVGCCLTSCTSNYHFMCSRAKN CVFLDDKKVYCQRHRDLIKGEVVPENGFEVFRRVFVDFEGISLRRKFLNG LEPENIHMMIGSMTIDCLGILNDLSDCEDKLFPIGYQCSRVYWSTTDARK RCVYTCKIVECRPPVVEPDINSTVEHDENRTIAHSPTSFTESSSKESQNT AEIISPPSPDRPPHSQTSGSCYYHVISKVPRIRTPSYSPTQRSPGCRPLP SAGSPTPTTHEIVTVGDPLLSSGLRSIGSRRHSTSSLSPQRSKLRIMSPM RTGNTYSRNNVSSVSTTGTATDLESSAKVVDHVLGPLNSSTSLGQNTSTS SNLQRTVVTVGNKNSHLDGSSSSEMKQSSASDLVSKSSSLKGEKTKVLSS KSSEGSAHNVAYPGIPKLAPQVHNTTSRELNVSKIGSFAEPSSVSFSSKE ALSFPHLHLRGQRNDRDQHTDSTQSANSSPDEDTEVKTLKLSGMSNRSSI INEHMGSSSRDRRQKGKKSCKETFKEKHSSKSFLEPGQVTTGEEGNLKPE FMDEVLTPEYMGQRPCNNVSSDKIGDKGLSMPGVPKAPPMQVEGSAKELQ APRKRTVKVTLTPLKMENESQSKNALKESSPASPLQIESTSPTEPISASE NPGDGPVAQPSPNNTSCQDSQSNNYQNLPVQDRNLMLPDGPKPQEDGSFK RRYPRRSARARSNMFFGLTPLYGVRSYGEEDIPFYSSSTGKKRGKRSAEG QVDGADDLSTSDEDDLYYYNFTRTVISSGGEERLASHNLFREEEQCDLPK ISQLDGVDDGTESDTSVTATTRKSSQIPKRNGKENGTENLKIDRPEDAGE KEHVTKSSVGHKNEPKMDNCHSVSRVKTQGQDSLEAQLSSLESSRRVHTS TPSDKNLLDTYNTELLKSDSDNNNSDDCGNILPSDIMDFVLKNTPSMQAL GESPESSSSELLNLGEGLGLDSNREKDMGLFEVFSQQLPTTEPVDSSVSS SISAEEQFELPLELPSDLSVLTTRSPTVPSQNPSRLAVISDSGEKRVTIT EKSVASSESDPALLSPGVDPTPEGHMTPDHFIQGHMDADHISSPPCGSVE QGHGNNQDLTRNSSTPGLQVPVSPTVPIQNQKYVPNSTDSPGPSQISNAA VQTTPPHLKPATEKLIVVNQNMQPLYVLQTLPNGVTQKIQLTSSVSSTPS VMETNTSVLGPMGGGLTLTTGLNPSLPTSQSLFPSASKGLLPMSHHQHLH SFPAATQSSFPPNISNPPSGLLIGVQPPPDPQLLVSESSQRTDLSTTVAT PSSGLKKRPISRLQTRKNKKLAPSSTPSNIAPSDVVSNMTLINFTPSQLP NHPSLLDLGSLNTSSHRTVPNIIKRSKSSIMYFEPAPLLPQSVGGTAATA AGTSTISQDTSHLTSGSVSGLASSSSVLNVVSMQTTTTPTSSASVPGHVT LTNPRLLGTPDIGSISNLLIKASQQSLGIQDQPVALPPSSGMFPQLGTSQ TPSTAAITAASSICVLPSTQTTGITAASPSGEADEHYQLQHVNQLLASKT GIHSSQRDLDSASGPQVSNFTQTVDAPNSMGLEQNKALSSAVQASPTSPG GSPSSPSSGQRSASPSVPGPTKPKPKTKRFQLPLDKGNGKKHKVSHLRTS SSEAHIPDQETTSLTSGTGTPGAEAEQQDTASVEQSSQKECGQPAGQVAV LPEVQVTQNPANEQESAEPKTVEEEESNFSSPLMLWLQQEQKRKESITEK KPKKGLVFEISSDDGFQICAESIEDAWKSLTDKVQEARSNARLKQLSFAG VNGLRMLGILHDAVVFLIEQLSGAKHCRNYKFRFHKPEEANEPPLNPHGS ARAEVHLRKSAFDMFNFLASKHRQPPEYNPNDEEEEEVQLKSARRATSMD LPMPMRFRHLKKTSKEAVGVYRSPIHGRGLFCKRNIDAGEMVIEYAGNVI RSIQTDKREKYYDSKGIGCYMFRIDDSEVVDATMHGNAARFINHSCEPNC YSRVINIDGQKHIVIFAMRKIYRGEELTYDYKFPIEDASNKLPCNCGAKK | 2956 | |
| PDB file (1240) | AFF1 | chr4 | 87968746 | + | KMT2A | chr11 | 118354897 | METMAFTERVNSSGNSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPL FGEPYKTAKGDELSSRIQNMLGNYEEVKEFLSTKSHTHRLDASENRLGKP KYPLIPDKGSSIPSSSFHTSVHHQSIHTPASGPLSVGNISHNPKMAQPRT EPMPSLHAKSCGPPDSQHLTQDRLGQEGFGSSHHKKGDRRADGDHCASVT DSAPERELSPLISLPSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNNSKGY CPAKSPKDLAVKVHDKETPQDSLVAPAQPPSQTFPPPSLPSKSVAMQQKP TAYVRPMDGQDQAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKM PSQSVEEKPPPVNKQENAGTLNILSTLSNGNSSKQKIPADGVHRIRVDFK EDCEAENVWEMGGLGILTSVPITPRVVCFLCASSGHVEFVYCQVCCEPFH KFCLEENERPLEDQLENWCCRRCKFCHVCGRQHQATKQLLECNKCRNSYH PECLGPNYPTKPTKKKKVWICTKCVRCKSCGSTTPGKGWDAQWSHDFSLC HDCAKLFAKGNFCPLCDKCYDDDDYESKMMQCGKCDRWVHSKCENLSDEM YEILSNLPESVAYTCVNCTERHPAEWRLALEKELQISLKQVLTALLNSRT TSHLLRYRQAAKPPDLNPETEESIPSRSSPEGPDPPVLTEVSKQDDQQPL DLEGVKRKMDQGNYTSVLEFSDDIVKIIQAAINSDGGQPEIKKANSMVKS FFIRQMERVFPWFSVKKSRFWEPNKVSSNSGMLPNAVLPPSLDHNYAQWQ EREENSHTEQPPLMKKIIPAPKPKGPGEPDSPTPLHPPTPPILSTDRSRE DSPELNPPPGIEDNRQCALCLTYGDDSANDAGRLLYIGQNEWTHVNCALW SAEVFEDDDGSLKNVHMAVIRGKQLRCEFCQKPGATVGCCLTSCTSNYHF MCSRAKNCVFLDDKKVYCQRHRDLIKGEVVPENGFEVFRRVFVDFEGISL RRKFLNGLEPENIHMMIGSMTIDCLGILNDLSDCEDKLFPIGYQCSRVYW STTDARKRCVYTCKIVECRPPVVEPDINSTVEHDENRTIAHSPTSFTESS SKESQNTAEIISPPSPDRPPHSQTSGSCYYHVISKVPRIRTPSYSPTQRS PGCRPLPSAGSPTPTTHEIVTVGDPLLSSGLRSIGSRRHSTSSLSPQRSK LRIMSPMRTGNTYSRNNVSSVSTTGTATDLESSAKVVDHVLGPLNSSTSL GQNTSTSSNLQRTVVTVGNKNSHLDGSSSSEMKQSSASDLVSKSSSLKGE KTKVLSSKSSEGSAHNVAYPGIPKLAPQVHNTTSRELNVSKIGSFAEPSS VSFSSKEALSFPHLHLRGQRNDRDQHTDSTQSANSSPDEDTEVKTLKLSG MSNRSSIINEHMGSSSRDRRQKGKKSCKETFKEKHSSKSFLEPGQVTTGE EGNLKPEFMDEVLTPEYMGQRPCNNVSSDKIGDKGLSMPGVPKAPPMQVE GSAKELQAPRKRTVKVTLTPLKMENESQSKNALKESSPASPLQIESTSPT EPISASENPGDGPVAQPSPNNTSCQDSQSNNYQNLPVQDRNLMLPDGPKP QEDGSFKRRYPRRSARARSNMFFGLTPLYGVRSYGEEDIPFYSSSTGKKR GKRSAEGQVDGADDLSTSDEDDLYYYNFTRTVISSGGEERLASHNLFREE EQCDLPKISQLDGVDDGTESDTSVTATTRKSSQIPKRNGKENGTENLKID RPEDAGEKEHVTKSSVGHKNEPKMDNCHSVSRVKTQGQDSLEAQLSSLES SRRVHTSTPSDKNLLDTYNTELLKSDSDNNNSDDCGNILPSDIMDFVLKN TPSMQALGESPESSSSELLNLGEGLGLDSNREKDMGLFEVFSQQLPTTEP VDSSVSSSISAEEQFELPLELPSDLSVLTTRSPTVPSQNPSRLAVISDSG EKRVTITEKSVASSESDPALLSPGVDPTPEGHMTPDHFIQGHMDADHISS PPCGSVEQGHGNNQDLTRNSSTPGLQVPVSPTVPIQNQKYVPNSTDSPGP SQISNAAVQTTPPHLKPATEKLIVVNQNMQPLYVLQTLPNGVTQKIQLTS SVSSTPSVMETNTSVLGPMGGGLTLTTGLNPSLPTSQSLFPSASKGLLPM SHHQHLHSFPAATQSSFPPNISNPPSGLLIGVQPPPDPQLLVSESSQRTD LSTTVATPSSGLKKRPISRLQTRKNKKLAPSSTPSNIAPSDVVSNMTLIN FTPSQLPNHPSLLDLGSLNTSSHRTVPNIIKRSKSSIMYFEPAPLLPQSV GGTAATAAGTSTISQDTSHLTSGSVSGLASSSSVLNVVSMQTTTTPTSSA SVPGHVTLTNPRLLGTPDIGSISNLLIKASQQSLGIQDQPVALPPSSGMF PQLGTSQTPSTAAITAASSICVLPSTQTTGITAASPSGEADEHYQLQHVN QLLASKTGIHSSQRDLDSASGPQVSNFTQTVDAPNSMGLEQNKALSSAVQ ASPTSPGGSPSSPSSGQRSASPSVPGPTKPKPKTKRFQLPLDKGNGKKHK VSHLRTSSSEAHIPDQETTSLTSGTGTPGAEAEQQDTASVEQSSQKECGQ PAGQVAVLPEVQVTQNPANEQESAEPKTVEEEESNFSSPLMLWLQQEQKR KESITEKKPKKGLVFEISSDDGFQICAESIEDAWKSLTDKVQEARSNARL KQLSFAGVNGLRMLGILHDAVVFLIEQLSGAKHCRNYKFRFHKPEEANEP PLNPHGSARAEVHLRKSAFDMFNFLASKHRQPPEYNPNDEEEEEVQLKSA RRATSMDLPMPMRFRHLKKTSKEAVGVYRSPIHGRGLFCKRNIDAGEMVI EYAGNVIRSIQTDKREKYYDSKGIGCYMFRIDDSEVVDATMHGNAARFIN HSCEPNCYSRVINIDGQKHIVIFAMRKIYRGEELTYDYKFPIEDASNKLP | 2963 | |
| PDB file (1241) | AFF1 | chr4 | 87968746 | + | KMT2A | chr11 | 118354897 | METMAFTERVNSSGNSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPL FGEPYKTAKGDELSSRIQNMLGNYEEVKEFLSTKSHTHRLDASENRLGKP KYPLIPDKGSSIPSSSFHTSVHHQSIHTPASGPLSVGNISHNPKMAQPRT EPMPSLHAKSCGPPDSQHLTQDRLGQEGFGSSHHKKGDRRADGDHCASVT DSAPERELSPLISLPSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNNSKGY CPAKSPKDLAVKVHDKETPQDSLVAPAQPPSQTFPPPSLPSKSVAMQQKP TAYVRPMDGQDQAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKM PSQSVEEKPPPVNKQENAGTLNILSTLSNGNSSKQKIPADGVHRIRVDFK EDCEAENVWEMGGLGILTSVPITPRVVCFLCASSGHVEFVYCQVCCEPFH KFCLEENERPLEDQLENWCCRRCKFCHVCGRQHQATKQLLECNKCRNSYH PECLGPNYPTKPTKKKKVWICTKCVRCKSCGSTTPGKGWDAQWSHDFSLC HDCAKLFAKGNFCPLCDKCYDDDDYESKMMQCGKCDRWVHSKCENLSGTE DEMYEILSNLPESVAYTCVNCTERHPAEWRLALEKELQISLKQVLTALLN SRTTSHLLRYRQAAKPPDLNPETEESIPSRSSPEGPDPPVLTEVSKQDDQ QPLDLEGVKRKMDQGNYTSVLEFSDDIVKIIQAAINSDGGQPEIKKANSM VKSFFIRQMERVFPWFSVKKSRFWEPNKVSSNSGMLPNAVLPPSLDHNYA QWQEREENSHTEQPPLMKKIIPAPKPKGPGEPDSPTPLHPPTPPILSTDR SREDSPELNPPPGIEDNRQCALCLTYGDDSANDAGRLLYIGQNEWTHVNC ALWSAEVFEDDDGSLKNVHMAVIRGKQLRCEFCQKPGATVGCCLTSCTSN YHFMCSRAKNCVFLDDKKVYCQRHRDLIKGEVVPENGFEVFRRVFVDFEG ISLRRKFLNGLEPENIHMMIGSMTIDCLGILNDLSDCEDKLFPIGYQCSR VYWSTTDARKRCVYTCKIVECRPPVVEPDINSTVEHDENRTIAHSPTSFT ESSSKESQNTAEIISPPSPDRPPHSQTSGSCYYHVISKVPRIRTPSYSPT QRSPGCRPLPSAGSPTPTTHEIVTVGDPLLSSGLRSIGSRRHSTSSLSPQ RSKLRIMSPMRTGNTYSRNNVSSVSTTGTATDLESSAKVVDHVLGPLNSS TSLGQNTSTSSNLQRTVVTVGNKNSHLDGSSSSEMKQSSASDLVSKSSSL KGEKTKVLSSKSSEGSAHNVAYPGIPKLAPQVHNTTSRELNVSKIGSFAE PSSVSFSSKEALSFPHLHLRGQRNDRDQHTDSTQSANSSPDEDTEVKTLK LSGMSNRSSIINEHMGSSSRDRRQKGKKSCKETFKEKHSSKSFLEPGQVT TGEEGNLKPEFMDEVLTPEYMGQRPCNNVSSDKIGDKGLSMPGVPKAPPM QVEGSAKELQAPRKRTVKVTLTPLKMENESQSKNALKESSPASPLQIEST SPTEPISASENPGDGPVAQPSPNNTSCQDSQSNNYQNLPVQDRNLMLPDG PKPQEDGSFKRRYPRRSARARSNMFFGLTPLYGVRSYGEEDIPFYSSSTG KKRGKRSAEGQVDGADDLSTSDEDDLYYYNFTRTVISSGGEERLASHNLF REEEQCDLPKISQLDGVDDGTESDTSVTATTRKSSQIPKRNGKENGTENL KIDRPEDAGEKEHVTKSSVGHKNEPKMDNCHSVSRVKTQGQDSLEAQLSS LESSRRVHTSTPSDKNLLDTYNTELLKSDSDNNNSDDCGNILPSDIMDFV LKNTPSMQALGESPESSSSELLNLGEGLGLDSNREKDMGLFEVFSQQLPT TEPVDSSVSSSISAEEQFELPLELPSDLSVLTTRSPTVPSQNPSRLAVIS DSGEKRVTITEKSVASSESDPALLSPGVDPTPEGHMTPDHFIQGHMDADH ISSPPCGSVEQGHGNNQDLTRNSSTPGLQVPVSPTVPIQNQKYVPNSTDS PGPSQISNAAVQTTPPHLKPATEKLIVVNQNMQPLYVLQTLPNGVTQKIQ LTSSVSSTPSVMETNTSVLGPMGGGLTLTTGLNPSLPTSQSLFPSASKGL LPMSHHQHLHSFPAATQSSFPPNISNPPSGLLIGVQPPPDPQLLVSESSQ RTDLSTTVATPSSGLKKRPISRLQTRKNKKLAPSSTPSNIAPSDVVSNMT LINFTPSQLPNHPSLLDLGSLNTSSHRTVPNIIKRSKSSIMYFEPAPLLP QSVGGTAATAAGTSTISQDTSHLTSGSVSGLASSSSVLNVVSMQTTTTPT SSASVPGHVTLTNPRLLGTPDIGSISNLLIKASQQSLGIQDQPVALPPSS GMFPQLGTSQTPSTAAITAASSICVLPSTQTTGITAASPSGEADEHYQLQ HVNQLLASKTGIHSSQRDLDSASGPQVSNFTQTVDAPNSMGLEQNKALSS AVQASPTSPGGSPSSPSSGQRSASPSVPGPTKPKPKTKRFQLPLDKGNGK KHKVSHLRTSSSEAHIPDQETTSLTSGTGTPGAEAEQQDTASVEQSSQKE CGQPAGQVAVLPEVQVTQNPANEQESAEPKTVEEEESNFSSPLMLWLQQE QKRKESITEKKPKKGLVFEISSDDGFQICAESIEDAWKSLTDKVQEARSN ARLKQLSFAGVNGLRMLGILHDAVVFLIEQLSGAKHCRNYKFRFHKPEEA NEPPLNPHGSARAEVHLRKSAFDMFNFLASKHRQPPEYNPNDEEEEEVQL KSARRATSMDLPMPMRFRHLKKTSKEAVGVYRSPIHGRGLFCKRNIDAGE MVIEYAGNVIRSIQTDKREKYYDSKGIGCYMFRIDDSEVVDATMHGNAAR FINHSCEPNCYSRVINIDGQKHIVIFAMRKIYRGEELTYDYKFPIEDASN | 2966 | |
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pLDDT score distribution |
| pLDDT score distribution of the predicted wild-type structures of two partner proteins from AlphaFold2 * AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. |
AFF1_pLDDT.png  |
KMT2A_pLDDT.png  |
| pLDDT score distribution of the predicted fusion protein structures from AlphaFold2 * AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. |
AFF1_KMT2A_1144_pLDDT.png (AA BP:46) |
AFF1_KMT2A_1147_pLDDT.png (AA BP:46) |
AFF1_KMT2A_1150_pLDDT.png (AA BP:56) |
AFF1_KMT2A_1152_pLDDT.png (AA BP:56) |
AFF1_KMT2A_1158_pLDDT.png (AA BP:46) |
AFF1_KMT2A_1163_pLDDT.png (AA BP:56) |
AFF1_KMT2A_1163_pLDDT_and_active_sites.png (AA BP:56) |
AFF1_KMT2A_1163_violinplot.png (AA BP:56) |
AFF1_KMT2A_1172_pLDDT.png (AA BP:46) |
AFF1_KMT2A_1172_pLDDT_and_active_sites.png (AA BP:46) |
AFF1_KMT2A_1172_violinplot.png (AA BP:46) |
AFF1_KMT2A_1174_pLDDT.png (AA BP:46) |
AFF1_KMT2A_1177_pLDDT.png (AA BP:56) |
AFF1_KMT2A_1180_pLDDT.png (AA BP:56) |
AFF1_KMT2A_1180_pLDDT_and_active_sites.png (AA BP:56) |
AFF1_KMT2A_1180_violinplot.png (AA BP:56) |
AFF1_KMT2A_1226_pLDDT.png (AA BP:346) |
AFF1_KMT2A_1226_pLDDT_and_active_sites.png (AA BP:346) |
AFF1_KMT2A_1226_violinplot.png (AA BP:346) |
AFF1_KMT2A_1238_pLDDT_and_active_sites.png (AA BP:) |
AFF1_KMT2A_1238_violinplot.png (AA BP:) |
AFF1_KMT2A_1239_pLDDT_and_active_sites.png (AA BP:) |
AFF1_KMT2A_1239_violinplot.png (AA BP:) |
AFF1_KMT2A_1240_pLDDT_and_active_sites.png (AA BP:) |
AFF1_KMT2A_1240_violinplot.png (AA BP:) |
AFF1_KMT2A_1241_pLDDT_and_active_sites.png (AA BP:) |
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Ramachandran Plot of Fusion Protein Structure |
| Ramachandran plot of the torsional angles - phi (φ)and psi (ψ) - of the residues (amino acids) contained in this fusion protein peptide. |
| Fusion AA seq ID in FusionPDB and their Ramachandran plots |
| AFF1_KMT2A_1163.png |
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| AFF1_KMT2A_1172.png |
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| AFF1_KMT2A_1180.png |
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| AFF1_KMT2A_1226.png |
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Potential Active Site Information |
| The potential binding sites of these fusion proteins were identified using SiteMap, a module of the Schrodinger suite. |
| Fusion AA seq ID in FusionPDB | Site score | Size | D score | Volume | Exposure | Enclosure | Contact | Phobic | Philic | Balance | Don/Acc | Residues |
| 1163 | 1.016 | 159 | 1.062 | 464.079 | 0.642 | 0.668 | 0.815 | 0.539 | 0.854 | 0.631 | 0.801 | Chain A: 105,119,120,121,122,123,126,129,130,131,1 32,133,135,136,137,139,145,150,151,152,153,154,155 ,158,159,160,179,180,181 |
| 1172 | 1.108 | 124 | 1.126 | 215.404 | 0.444 | 0.839 | 1.087 | 0.951 | 0.973 | 0.977 | 0.911 | Chain A: 87,88,89,90,91,104,105,107,121,122,123,57 5,576,578,579,682,683,685,688,689,690,694,695,705 |
| 1180 | 1.024 | 186 | 1.047 | 326.536 | 0.503 | 0.721 | 0.922 | 0.576 | 0.997 | 0.577 | 0.887 | Chain A: 97,98,99,100,101,102,103,104,114,115,116, 117,118,131,132,133,588,589,590,591,592,612,614,61 6,619,695,696,697,698,699,700,701,703,707,711,716 |
| 1226 | 1.116 | 234 | 1.146 | 714.469 | 0.406 | 0.829 | 1.095 | 1.055 | 0.893 | 1.181 | 0.813 | Chain A: 384,385,386,387,388,389,391,393,399,400,4 01,402,404,405,424,817,827,835,836,837,838,844,942 ,943,944,967,968,969,970,971,973,1000,1012,1574,15 75,1576,1577,1578,1579,2670,2672 |
| 1238 | 1.06 | 183 | 1.046 | 296.009 | 0.419 | 0.787 | 1.042 | 0.897 | 1.123 | 0.798 | 0.808 | Chain A: 433,446,447,448,449,450,451,454,456,457,4 58,459,464,465,467,470,481,485,486,487,488,2685,26 90,2691,2692,2693,2694 |
| 1239 | 1.009 | 408 | 0.981 | 1073.933 | 0.511 | 0.711 | 0.957 | 0.317 | 1.181 | 0.268 | 0.669 | Chain A: 142,143,144,145,146,147,396,399,400,402,4 19,433,434,435,437,441,446,447,448,449,450,451,454 ,456,457,458,459,461,462,463,464,465,467,472,473,4 74,475,478,479,480,481,483,485,486,487,488,491,502 ,506,507,508,509,1010,1040,2688,2694,2695,2696,269 7,2700,2701,2705,2706 |
| 1240 | 1.015 | 313 | 1.047 | 920.955 | 0.591 | 0.694 | 0.876 | 0.78 | 0.951 | 0.821 | 0.966 | Chain A: 101,102,103,104,105,109,110,111,138,139,1 40,141,1680,1681,1682,1683,1684,2245,2246,2247,224 8,2249,2250,2252,2254,2748,2749,2750,2751,2752,275 3,2754,2755,2756,2757,2758,2776,2778,2780,2781,278 2,2783,2784,2785,2829,2830,2831,2832,2834,2838,290 2,2904,2905,2906,2926,2931,2932,2933,2935,2952,295 3,2954,2955,2956,2957,2958,2960 |
| 1241 | 1.021 | 170 | 0.985 | 344.029 | 0.524 | 0.73 | 0.975 | 0.394 | 1.206 | 0.327 | 0.415 | Chain A: 406,409,410,411,412,429,444,445,447,471,4 72,473,474,482,483,484,485,489,1020,1023,1039,1040 ,1041,1050,2710,2711,2712,2715,2716,2718,2719,2720 ,2721,2722,2725,2740,2743 |
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Potentially Interacting Small Molecules through Virtual Screening |
| The FDA-approved small molecule library molecules were subjected to virtual screening using the Glide. |
| Fusion AA seq ID in FusionPDB | ZINC ID | DrugBank ID | Drug name | Docking score | Glide gscore |
| 1163 | ZINC000029571072 | DB06636 | Isavuconazonium | -7.86361 | -9.76831 |
| 1163 | ZINC000150588351 | DB11574 | Elbasvir | -8.11272 | -9.25662 |
| 1163 | ZINC000049637509 | DB06636 | Isavuconazonium | -7.1712 | -9.0759 |
| 1163 | ZINC000028232755 | DB00385 | Valrubicin | -8.26905 | -8.26935 |
| 1163 | ZINC000068204830 | DB09102 | Daclatasvir | -7.30435 | -8.16905 |
| 1163 | ZINC000003830960 | DB09156 | Iopromide | -8.13287 | -8.13287 |
| 1163 | ZINC000000537822 | DB00502 | Haloperidol | -5.70824 | -7.95994 |
| 1163 | ZINC000026985532 | DB01232 | Saquinavir | -7.7936 | -7.8068 |
| 1163 | ZINC000026664090 | DB01232 | Saquinavir | -7.77924 | -7.79244 |
| 1163 | ZINC000028232746 | DB00385 | Valrubicin | -7.76585 | -7.76615 |
| 1163 | Tucatinib | DB00385 | -7.35428 | -7.72948 | |
| 1163 | ZINC000000006300 | DB00962 | Zaleplon | -7.66607 | -7.66607 |
| 1163 | ZINC000070466416 | DB08875 | Cabozantinib | -7.60268 | -7.64768 |
| 1163 | ZINC000256097222 | DB11602 | Hydroxyethyl cellulose | -7.45383 | -7.45383 |
| 1163 | ZINC000022448696 | DB00224 | Indinavir | -7.05368 | -7.44448 |
| 1163 | ZINC000000403011 | DB00598 | Labetalol | -7.40649 | -7.43409 |
| 1163 | ZINC000003831151 | DB00471 | Montelukast | -7.40366 | -7.40366 |
| 1163 | ZINC000001996784 | DB08893 | Mirabegron | -7.23022 | -7.39822 |
| 1163 | ZINC000027990463 | DB08827 | Lomitapide | -7.3676 | -7.3707 |
| 1163 | ZINC000003830957 | DB09156 | Iopromide | -7.36639 | -7.36639 |
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| Drug information from DrugBank of the top 20 interacting small molecules. |
| ZINC ID | DrugBank ID | Drug name | Drug type | SMILES | Drug group |
| ZINC000150588351 | DB11574 | Elbasvir | Small molecule | [H][C@]1(CCCN1C(=O)[C@@H](NC(=O)OC)C(C)C)C1=NC=C(N1)C1=CC2=C(C=C1)N1[C@@H](OC3=C(C=CC(=C3)C3=CN=C(N3)[C@]3([H])CCCN3C(=O)[C@@H](NC(=O)OC)C(C)C)C1=C2)C1=CC=CC=C1 | Approved |
| ZINC000049637509 | DB06636 | Isavuconazonium | Small molecule | [H]C(C)(OC(=O)N(C)C1=C(COC(=O)CNC)C=CC=N1)[N+]1=CN(C[C@](O)(C2=C(F)C=CC(F)=C2)[C@@]([H])(C)C2=NC(=CS2)C2=CC=C(C=C2)C#N)N=C1 | Approved|Investigational |
| ZINC000068204830 | DB09102 | Daclatasvir | Small molecule | COC(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1C1=NC=C(N1)C1=CC=C(C=C1)C1=CC=C(C=C1)C1=CN=C(N1)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OC)C(C)C | Approved|Investigational |
| ZINC000000537822 | DB00502 | Haloperidol | Small molecule | OC1(CCN(CCCC(=O)C2=CC=C(F)C=C2)CC1)C1=CC=C(Cl)C=C1 | Approved |
| ZINC000000006300 | DB00962 | Zaleplon | Small molecule | CCN(C(C)=O)C1=CC=CC(=C1)C1=CC=NC2=C(C=NN12)C#N | Approved|Illicit|Investigational |
| ZINC000070466416 | DB08875 | Cabozantinib | Small molecule | COC1=CC2=C(C=C1OC)C(OC1=CC=C(NC(=O)C3(CC3)C(=O)NC3=CC=C(F)C=C3)C=C1)=CC=N2 | Approved|Investigational |
| ZINC000022448696 | DB00224 | Indinavir | Small molecule | CC(C)(C)NC(=O)[C@@H]1CN(CC2=CN=CC=C2)CCN1C[C@@H](O)C[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H]1[C@H](O)CC2=CC=CC=C12 | Approved |
| ZINC000000403011 | DB00598 | Labetalol | Small molecule | CC(CCC1=CC=CC=C1)NCC(O)C1=CC(C(N)=O)=C(O)C=C1 | Approved |
| ZINC000003831151 | DB00471 | Montelukast | Small molecule | OC(=O)CC1(CC1)CS[C@H](CCC1=CC=CC=C1C(O)(C)C)C1=CC=CC(C=CC2=NC3=C(C=CC(Cl)=C3)C=C2)=C1 | Approved |
| ZINC000001996784 | DB08893 | Mirabegron | Small molecule | NC1=NC(CC(=O)NC2=CC=C(CCNC[C@H](O)C3=CC=CC=C3)C=C2)=CS1 | Approved |
| ZINC000027990463 | DB08827 | Lomitapide | Small molecule | FC(F)(F)CNC(=O)C1(CCCCN2CCC(CC2)NC(=O)C2=C(C=CC=C2)C2=CC=C(C=C2)C(F)(F)F)C2=CC=CC=C2C2=CC=CC=C12 | Approved|Investigational |
| ZINC000003830957 | DB09156 | Iopromide | Small molecule | COCC(=O)NC1=C(I)C(C(=O)N(C)CC(O)CO)=C(I)C(C(=O)NCC(O)CO)=C1I | Approved |
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Biochemical Features of Small Molecules |
| ADME (Absorption, Distribution, Metabolism, and Excretion) of drugs using QikProp(v3.9) |
| ZINC ID | mol_MW | dipole | SASA | FOSA | FISA | PISA | WPSA | volume | donorHB | accptHB | IP | Human Oral Absorption | Percent Human Oral Absorption | Rule Of Five | Rule Of Three |
| ZINC000150588351 | 882.03 | 6.572 | 1345.74 | 717.517 | 186.345 | 441.878 | 0 | 2635.972 | 2.5 | 13.25 | 8.001 | 1 | 68.973 | 3 | 1 |
| ZINC000150588351 | 882.03 | 15.581 | 1298.014 | 670.728 | 196.39 | 430.896 | 0 | 2598.655 | 2.5 | 13.25 | 8.107 | 1 | 65.891 | 3 | 1 |
| ZINC000150588351 | 882.03 | 7.694 | 1389.327 | 750.107 | 173.462 | 465.758 | 0 | 2673.848 | 2.5 | 13.25 | 8.124 | 1 | 73.085 | 3 | 1 |
| ZINC000150588351 | 882.03 | 2.219 | 1373.023 | 721.483 | 195.055 | 456.485 | 0 | 2655.192 | 2.5 | 13.25 | 8.091 | 1 | 68.497 | 3 | 1 |
| ZINC000150588351 | 882.03 | 13.761 | 1347.364 | 706.26 | 205.501 | 435.603 | 0 | 2635.257 | 2.5 | 13.25 | 8.253 | 1 | 64.824 | 3 | 1 |
| ZINC000150588351 | 882.03 | 6.922 | 1403.807 | 740.212 | 182.531 | 481.064 | 0 | 2678.744 | 2.5 | 13.25 | 8.307 | 1 | 71.991 | 3 | 1 |
| ZINC000150588351 | 882.03 | 13.99 | 1367.982 | 729.766 | 188.685 | 449.531 | 0 | 2678.673 | 2.5 | 13.25 | 7.973 | 1 | 70.208 | 3 | 2 |
| ZINC000150588351 | 882.03 | 10.656 | 1391.126 | 719.587 | 194.166 | 477.373 | 0 | 2673.624 | 2.5 | 13.25 | 7.937 | 1 | 69.244 | 3 | 2 |
| ZINC000150588351 | 882.03 | 8.233 | 1375.056 | 718.117 | 197.908 | 459.032 | 0 | 2655.63 | 2.5 | 13.25 | 7.962 | 1 | 67.787 | 3 | 2 |
| ZINC000028232755 | 723.653 | 2.65 | 1042.026 | 492.004 | 317.032 | 110.408 | 122.581 | 1989.623 | 3 | 16.6 | 9.032 | 2 | 27.807 | 2 | 3 |
| ZINC000068204830 | 738.885 | 9.186 | 1185.225 | 698.369 | 189.608 | 297.248 | 0 | 2297.481 | 2.5 | 12.5 | 8.424 | 1 | 56.25 | 3 | 1 |
| ZINC000068204830 | 738.885 | 12.728 | 1242.653 | 732.724 | 195.462 | 314.467 | 0 | 2325.851 | 2.5 | 12.5 | 8.586 | 1 | 56.993 | 3 | 1 |
| ZINC000068204830 | 738.885 | 5.659 | 1215.343 | 718.68 | 189.061 | 307.602 | 0 | 2308.854 | 2.5 | 12.5 | 8.456 | 1 | 57.668 | 3 | 1 |
| ZINC000068204830 | 738.885 | 3.036 | 1238.237 | 724.613 | 189.774 | 323.849 | 0 | 2337.465 | 2.5 | 12.5 | 8.529 | 1 | 58.588 | 3 | 1 |
| ZINC000068204830 | 738.885 | 6.612 | 1209.345 | 719.031 | 182.477 | 307.837 | 0 | 2307.347 | 2.5 | 12.5 | 8.288 | 1 | 59.648 | 3 | 1 |
| ZINC000068204830 | 738.885 | 4.849 | 1244.561 | 737.115 | 179.716 | 327.731 | 0 | 2332.759 | 2.5 | 12.5 | 8.571 | 1 | 60.798 | 3 | 1 |
| ZINC000003830960 | 791.116 | 13.331 | 796.713 | 372.732 | 270.922 | 13.115 | 139.944 | 1454.391 | 6 | 16.5 | 9.452 | 2 | 12.864 | 3 | 0 |
| ZINC000000537822 | 375.87 | 3.194 | 684.196 | 209.603 | 68.864 | 287.369 | 118.36 | 1199.714 | 1 | 4.75 | 9.391 | 3 | 100 | 0 | 0 |
| ZINC000000537822 | 375.87 | 2.935 | 674.977 | 199.704 | 83.514 | 273.376 | 118.382 | 1195.364 | 1 | 4.75 | 9.357 | 3 | 100 | 0 | 0 |
| ZINC000000537822 | 375.87 | 4.967 | 684.834 | 209.154 | 69.652 | 287.663 | 118.365 | 1206.223 | 1 | 4.75 | 9.266 | 3 | 100 | 0 | 0 |
| ZINC000026985532 | 670.85 | 2.992 | 1090.203 | 522.841 | 198.112 | 369.25 | 0 | 2103.734 | 5 | 13.7 | 8.881 | 2 | 23.062 | 3 | 2 |
| ZINC000026985532 | 670.85 | 8.593 | 1062.24 | 515.596 | 176.807 | 369.837 | 0 | 2085.965 | 5 | 13.7 | 9.245 | 2 | 25.698 | 3 | 2 |
| ZINC000026985532 | 670.85 | 2.719 | 1077.343 | 520.688 | 191.958 | 364.697 | 0 | 2094.541 | 5 | 13.7 | 8.976 | 2 | 25 | 3 | 2 |
| ZINC000026664090 | 670.85 | 8.176 | 1065.378 | 519.173 | 193.936 | 352.269 | 0 | 2081.598 | 5 | 13.7 | 8.874 | 2 | 24.528 | 3 | 2 |
| ZINC000026664090 | 670.85 | 7.138 | 1070.742 | 492.821 | 201.426 | 376.495 | 0 | 2080.089 | 5 | 13.7 | 9.102 | 2 | 19.952 | 3 | 2 |
| ZINC000026664090 | 670.85 | 8.491 | 1112.722 | 519.438 | 188.94 | 404.343 | 0 | 2123.763 | 5 | 13.7 | 8.939 | 2 | 26.753 | 3 | 2 |
| ZINC000028232746 | 723.653 | 3.501 | 1029.981 | 485.542 | 308.279 | 111.017 | 125.143 | 1980.071 | 3 | 16.6 | 8.957 | 2 | 29.549 | 2 | 3 |
| ZINC000000006300 | 305.338 | 7.755 | 592.047 | 183.731 | 150.968 | 257.348 | 0 | 1021.542 | 0 | 6.5 | 9.379 | 3 | 84.513 | 0 | 0 |
| ZINC000070466416 | 501.513 | 5.317 | 864.11 | 297.804 | 81.657 | 437.831 | 46.818 | 1529.939 | 0 | 6 | 8.814 | 1 | 96.634 | 2 | 1 |
| ZINC000070466416 | 501.513 | 5.04 | 863.932 | 298.029 | 82.934 | 436.155 | 46.814 | 1529.364 | 0 | 6 | 8.815 | 1 | 96.332 | 2 | 1 |
| ZINC000256097222 | 806.938 | 4.597 | 1196.074 | 907.255 | 288.819 | 0 | 0 | 2456.881 | 8 | 32.3 | 10.172 | 1 | 2.277 | 3 | 2 |
| ZINC000022448696 | 613.798 | 6.954 | 1035.321 | 444.196 | 106.92 | 484.205 | 0 | 1983.74 | 4 | 13.9 | 8.672 | 1 | 60.656 | 1 | 1 |
| ZINC000022448696 | 613.798 | 4.692 | 987.892 | 420.483 | 105.118 | 462.291 | 0 | 1950.085 | 4 | 13.9 | 9.459 | 1 | 57.593 | 1 | 1 |
| ZINC000022448696 | 613.798 | 4.883 | 996.709 | 456.592 | 90.226 | 449.891 | 0 | 1954.069 | 4 | 13.9 | 9.026 | 1 | 61.724 | 1 | 1 |
| ZINC000022448696 | 613.798 | 4.038 | 892.447 | 367.68 | 134.761 | 390.006 | 0 | 1866.081 | 4 | 13.9 | 9.424 | 1 | 49.06 | 1 | 2 |
| ZINC000022448696 | 613.798 | 6.203 | 1015.231 | 403.285 | 139.932 | 472.014 | 0 | 1971.466 | 4 | 13.9 | 9.391 | 1 | 49.786 | 1 | 2 |
| ZINC000000403011 | 328.41 | 5.963 | 663.486 | 168.781 | 199.564 | 295.141 | 0 | 1140.577 | 4 | 5.45 | 9.137 | 2 | 70.605 | 0 | 0 |
| ZINC000000403011 | 328.41 | 5.239 | 606.942 | 175.803 | 170.799 | 260.34 | 0 | 1103.551 | 4 | 5.45 | 9.225 | 3 | 75.44 | 0 | 0 |
| ZINC000003831151 | 586.187 | 2.651 | 1004.488 | 333.455 | 125.421 | 452.355 | 93.257 | 1886.43 | 2 | 4.25 | 8.788 | 1 | 100 | 2 | 1 |
| ZINC000001996784 | 396.506 | 5.759 | 766.121 | 167.737 | 163.909 | 381.056 | 53.42 | 1313.347 | 5 | 7.7 | 8.494 | 3 | 75.071 | 0 | 0 |
| ZINC000001996784 | 396.506 | 5.465 | 768.333 | 168.285 | 165.496 | 381.315 | 53.237 | 1317.855 | 5 | 7.7 | 8.411 | 3 | 74.89 | 0 | 0 |
| ZINC000027990463 | 693.731 | 9.819 | 1082.565 | 277.602 | 57.032 | 525.312 | 222.618 | 2026.285 | 2 | 7 | 9.293 | 1 | 100 | 2 | 1 |
| ZINC000027990463 | 693.731 | 5.182 | 1032.195 | 249.812 | 56.285 | 513.578 | 212.521 | 1985.783 | 2 | 7 | 9.074 | 1 | 100 | 2 | 1 |
| ZINC000003830957 | 791.116 | 18.635 | 789.873 | 365.18 | 274.531 | 12.737 | 137.425 | 1448.372 | 6 | 16.5 | 9.13 | 2 | 11.93 | 3 | 0 |
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Drug Toxicity Information |
| Toxicity information of individual drugs using eToxPred |
| ZINC ID | Smile | Surface Accessibility | Toxicity |
| ZINC000029571072 | CNCC(=O)OCc1cccnc1N(C)C(=O)O[C@H](C)[n+]1cnn(C[C@](O)(c2cc(F)ccc2F)[C@@H](C)c2nc(-c3ccc(C#N)cc3)cs2)c1 | 0.025416027 | 0.235213823 |
| ZINC000150588351 | COC(=O)N[C@H](C(=O)N1CCC[C@H]1c1nc(-c2ccc3c(c2)O[C@@H](c2ccccc2)n2c-3cc3cc(-c4c[nH]c([C@@H]5CCCN5C(=O)[C@@H](NC(=O)OC)C(C)C)n4)ccc32)c[nH]1)C(C)C | 0.015875917 | 0.217012798 |
| ZINC000049637509 | CNCC(=O)OCc1cccnc1N(C)C(=O)O[C@@H](C)[n+]1cnn(C[C@](O)(c2cc(F)ccc2F)[C@@H](C)c2nc(-c3ccc(C#N)cc3)cs2)c1 | 0.025416027 | 0.235213823 |
| ZINC000028232755 | CCCCC(=O)OCC(=O)[C@]1(O)Cc2c(O)c3c(c(O)c2[C@@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@@H](O)[C@@H](C)O2)C1)C(=O)c1c(OC)cccc1C3=O | 0.023056992 | 0.246049783 |
| ZINC000068204830 | COC(=O)N[C@H](C(=O)N1CCC[C@H]1c1ncc(-c2ccc(-c3ccc(-c4cnc([C@@H]5CCCN5C(=O)[C@@H](NC(=O)OC)C(C)C)[nH]4)cc3)cc2)[nH]1)C(C)C | 0.039971092 | 0.226481814 |
| ZINC000003830960 | COCC(=O)Nc1c(I)c(C(=O)NC[C@@H](O)CO)c(I)c(C(=O)N(C)C[C@@H](O)CO)c1I | 0.060949553 | 0.263153665 |
| ZINC000000537822 | O=C(CCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1ccc(F)cc1 | 0.325389417 | 0.260800529 |
| ZINC000026985532 | CC(C)(C)NC(=O)[C@@H]1C[C@H]2CCCC[C@@H]2CN1C[C@@H](O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(N)=O)NC(=O)c1ccc2ccccc2n1 | 0.039248776 | 0.333476835 |
| ZINC000026664090 | CC(C)(C)NC(=O)[C@@H]1C[C@@H]2CCCC[C@H]2CN1C[C@@H](O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(N)=O)NC(=O)c1ccc2ccccc2n1 | 0.039248776 | 0.333476835 |
| ZINC000028232746 | CCCCC(=O)OCC(=O)[C@]1(O)Cc2c(O)c3c(c(O)c2[C@@H](O[C@H]2C[C@@H](NC(=O)C(F)(F)F)[C@@H](O)[C@@H](C)O2)C1)C(=O)c1c(OC)cccc1C3=O | 0.023056992 | 0.246049783 |
| ZINC000000006300 | CCN(C(C)=O)c1cccc(-c2ccnc3c(C#N)cnn23)c1 | 0.20537037 | 0.301287055 |
| ZINC000070466416 | COc1cc2nccc(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3)c2cc1OC | 0.242538091 | 0.189405869 |
| ZINC000256097222 | C[C@H](O)COC[C@@H]1O[C@H](O[C@@H]2[C@H](COC[C@H](C)O)O[C@@H](OC[C@H](C)O)[C@H](OC[C@H](C)O)[C@@H]2OC[C@H](C)O)[C@@H](OC[C@H](C)O)[C@H](OC[C@H](C)O)[C@H]1OC[C@@H](C)O | 0.009383106 | 0.53116051 |
| ZINC000022448696 | CC(C)(C)NC(=O)[C@@H]1CN(Cc2cccnc2)CCN1C[C@@H](O)C[C@@H](Cc1ccccc1)C(=O)N[C@H]1c2ccccc2C[C@H]1O | 0.045517594 | 0.324414178 |
| ZINC000000403011 | C[C@@H](CCc1ccccc1)NC[C@@H](O)c1ccc(O)c(C(N)=O)c1 | 0.163888793 | 0.349082082 |
| ZINC000003831151 | CC(C)(O)c1ccccc1CC[C@@H](SCC1(CC(=O)O)CC1)c1cccc(/C=C/c2ccc3ccc(Cl)cc3n2)c1 | 0.079998455 | 0.32708243 |
| ZINC000001996784 | Nc1nc(CC(=O)Nc2ccc(CCNC[C@H](O)c3ccccc3)cc2)cs1 | 0.20568106 | 0.138337618 |
| ZINC000027990463 | O=C(NC1CCN(CCCCC2(C(=O)NCC(F)(F)F)c3ccccc3-c3ccccc32)CC1)c1ccccc1-c1ccc(C(F)(F)F)cc1 | 0.141091549 | 0.274261494 |
| ZINC000003830957 | COCC(=O)Nc1c(I)c(C(=O)NC[C@H](O)CO)c(I)c(C(=O)N(C)C[C@H](O)CO)c1I | 0.060949553 | 0.263153665 |
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Fusion Protein-Protein Interaction |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type from validated records (BIOGRID-3.4.160) |
| Gene | PPI interactors |
| AFF1 | MLLT1, CCNT1, NT5E, MLLT3, CDK9, AFF4, KMT2A, AFF1, BRD4, RELA, NPM1, PCSK1, MLLT10, DOT1L, POLR2A, DDX6, HEXIM1, HIST3H3, NSD1, CARM1, SIAH1, SIAH2, SMAD9, tat, MED26, EAF1, ELL2, LARP7, ELL3, HDAC1, MYH7, SLC16A6, ZNF526, Mllt1, Mad2l1bp, Rrbp1, Rcc1, VDR, PIP4K2A, CAMKV, TRIM25, HNRNPL, ESR2, KIAA1429, SASH1, DYRK1A, ARFIP1, MRPL12, KIF20A, CCAR2, FGF12, PLCD3, EPB41L1, EPB41L3, |
| KMT2A | PPIE, PPP1R15A, KMT2A, ASH2L, HCFC1, HCFC2, MEN1, RBBP5, WDR5, AVP, INS, OXT, MAP3K5, HDAC1, CTBP1, CBX4, BMI1, CREBBP, SMARCB1, CXXC1, MYB, CTNNB1, SNW1, E2F2, E2F4, E2F6, PSIP1, MLLT4, POLR2A, KAT8, RNF2, TP53, tat, SBF1, MTM1, SET, HIST1H3A, HIST1H4A, KAT6A, ELL, AFF1, AFF4, CDK9, CCNT1, CTR9, LEO1, PAF1, CDC73, WDR61, MLLT3, DOT1L, SKP2, HIST3H3, SVIL, HIST2H3C, SIN3A, MLLT1, RUNX1, CBFB, H3F3A, SIRT7, ASB2, TCEB1, TCEB2, CBX8, TOP1, TAF6, NCL, HECW2, LGR4, CSNK2A2, SENP3, SYMPK, PKN1, PIH1D1, KRAS, TAF1, CHD3, SMARCA2, SMARCC2, SMARCC1, HDAC2, RBBP4, RBBP7, TBP, MBD3, SAP30, RAN, TAF9, TASP1, HIST1H2BG, EWSR1, DYNLT1, KIF11, ING4, Cbx1, Set, ZNF131, ASB7, AR, CSNK2A1, OGT, BRD4, KDM5B, KDM5D, KDM6B, CKS1B, CKS2, CHD4, ESR2, AGR2, EZH2, FBXW7, SOX2, MED17, WDR82, ACTR8, GEMIN5, RUVBL1, MCM2, RTF1, MED15, MED8, MRGBP, MED14, HIST1H2BB, HIST1H2AB, KIAA1429, SP1, MYC, NR2C2, IRF2, PLEKHA4, DPY30, PTEN, NPM1, RPL13, CCT6A, TMCO1, ITGB1, ESR1, MYCN, SUPT5H, CIT, Pik3r2, FASN, LDLR, CDC27, KMT2B, SETD1A, KDM6A, KANSL2, BUB3, SETD1B, KANSL1, RERE, MCRS1, KMT2C, ZZZ3, MBIP, YEATS2, PAXIP1, KANSL3, KMT2D, BOD1L1, CSRP2BP, ZNF608, ATN1, PHF20L1, PHF20, NCOA6, TADA3, APEX1, ASF1A, CBX3, CD3EAP, CENPA, NUP50, POLR1E, TERF2IP, ZNF330, NAA40, PRKRA, SRSF4, KRR1, RPL13A, ABT1, CSNK2B, OASL, SRSF5, SRSF6, RPS9, FGFBP1, RPLP0, RPL36, KAL1, RPL3, PML, ELF1, ELF2, FEV, NHLH1, EN1, KLF12, KLF3, NFIX, NFYC, YY1, BRD3, |
| Protein-protein interactors based on sequence similarity (STRING) |
| Gene | STRING network |
| AFF1 |  |
| KMT2A |  |
| - Retained interactions in fusion protein (protein functional feature from UniProt). |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost interactions due to fusion (protein functional feature from UniProt). |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs to AFF1-KMT2A |
| Drugs used for this fusion-positive patient. (Manual curation of PubMed, 04-30-2022 + MyCancerGenome) |
| Hgene | Tgene | Drug | Source | PMID |
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Related Diseases to AFF1-KMT2A |
| Diseases that have this fusion gene. (Manual curation of PubMed, 04-30-2022 + MyCancerGenome) |
| Hgene | Tgene | Disease | Source | PMID |
| AFF1 | KMT2A | B-Cell Lymphoblastic Leukemia/Lymphoma B-Cell Lymphoblastic Leukemia/Lymphoma With T(V;11q23.3) | MyCancerGenome |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | KMT2A | C2826025 | Mixed phenotype acute leukemia | 3 | ORPHANET |
| Tgene | KMT2A | C0023418 | leukemia | 2 | CTD_human |
| Tgene | KMT2A | C0023452 | Childhood Acute Lymphoblastic Leukemia | 2 | CTD_human |
| Tgene | KMT2A | C0023453 | L2 Acute Lymphoblastic Leukemia | 2 | CTD_human |
| Tgene | KMT2A | C0023466 | Leukemia, Monocytic, Chronic | 2 | CTD_human |
| Tgene | KMT2A | C0023467 | Leukemia, Myelocytic, Acute | 2 | CTD_human |
| Tgene | KMT2A | C0023470 | Myeloid Leukemia | 2 | CTD_human |
| Tgene | KMT2A | C0026998 | Acute Myeloid Leukemia, M1 | 2 | CTD_human |
| Tgene | KMT2A | C1854630 | Growth Deficiency and Mental Retardation with Facial Dysmorphism | 2 | CTD_human;GENOMICS_ENGLAND;ORPHANET |
| Tgene | KMT2A | C1879321 | Acute Myeloid Leukemia (AML-M2) | 2 | CTD_human |
| Tgene | KMT2A | C1961102 | Precursor Cell Lymphoblastic Leukemia Lymphoma | 2 | CTD_human |
| Tgene | KMT2A | C0001418 | Adenocarcinoma | 1 | CTD_human |
| Tgene | KMT2A | C0004403 | Autosome Abnormalities | 1 | CTD_human |
| Tgene | KMT2A | C0005684 | Malignant neoplasm of urinary bladder | 1 | CTD_human |
| Tgene | KMT2A | C0005695 | Bladder Neoplasm | 1 | CTD_human |
| Tgene | KMT2A | C0007138 | Carcinoma, Transitional Cell | 1 | CTD_human |
| Tgene | KMT2A | C0008625 | Chromosome Aberrations | 1 | CTD_human |
| Tgene | KMT2A | C0023448 | Lymphoid leukemia | 1 | CTD_human |
| Tgene | KMT2A | C0023465 | Acute monocytic leukemia | 1 | CTD_human |
| Tgene | KMT2A | C0023479 | Acute myelomonocytic leukemia | 1 | CTD_human |
| Tgene | KMT2A | C0024623 | Malignant neoplasm of stomach | 1 | CTD_human |
| Tgene | KMT2A | C0033578 | Prostatic Neoplasms | 1 | CTD_human |
| Tgene | KMT2A | C0036341 | Schizophrenia | 1 | PSYGENET |
| Tgene | KMT2A | C0038356 | Stomach Neoplasms | 1 | CTD_human |
| Tgene | KMT2A | C0149925 | Small cell carcinoma of lung | 1 | CTD_human |
| Tgene | KMT2A | C0205641 | Adenocarcinoma, Basal Cell | 1 | CTD_human |
| Tgene | KMT2A | C0205642 | Adenocarcinoma, Oxyphilic | 1 | CTD_human |
| Tgene | KMT2A | C0205643 | Carcinoma, Cribriform | 1 | CTD_human |
| Tgene | KMT2A | C0205644 | Carcinoma, Granular Cell | 1 | CTD_human |
| Tgene | KMT2A | C0205645 | Adenocarcinoma, Tubular | 1 | CTD_human |
| Tgene | KMT2A | C0270972 | Cornelia De Lange Syndrome | 1 | ORPHANET |
| Tgene | KMT2A | C0280141 | Acute Undifferentiated Leukemia | 1 | ORPHANET |
| Tgene | KMT2A | C0376358 | Malignant neoplasm of prostate | 1 | CTD_human |
| Tgene | KMT2A | C0856823 | Undifferentiated type acute leukemia | 1 | ORPHANET |
| Tgene | KMT2A | C1535926 | Neurodevelopmental Disorders | 1 | CTD_human |
| Tgene | KMT2A | C1708349 | Hereditary Diffuse Gastric Cancer | 1 | CTD_human |
| Tgene | KMT2A | C2239176 | Liver carcinoma | 1 | CTD_human |
| Tgene | KMT2A | C2930974 | Acute erythroleukemia | 1 | CTD_human |
| Tgene | KMT2A | C2930975 | Acute erythroleukemia - M6a subtype | 1 | CTD_human |
| Tgene | KMT2A | C2930976 | Acute myeloid leukemia FAB-M6 | 1 | CTD_human |
| Tgene | KMT2A | C2930977 | Acute erythroleukemia - M6b subtype | 1 | CTD_human |
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