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Center for Computational Systems Medicine level2
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Fusion Gene Summary

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Fusion Gene Sample Information

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Fusion ORF Analysis

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Fusion Amino Acid Sequences

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Fusion Protein Functional Features

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Fusion Protein Structure

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pLDDT scores

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Ramachandran Plot of Fusion Protein Structure

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Fusion Protein-Protein Interaction

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Related drugs with this fusion protein

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Related disease with this fusion protein

Fusion Protein:EPB41L1-ROMO1

Fusion Protein Summary

check button Fusion gene summary
Fusion partner gene informationFusion gene name: EPB41L1-ROMO1
FusionPDB ID: 26823
FusionGDB2.0 ID: 26823
HgeneTgene
Gene symbol

EPB41L1

ROMO1

Gene ID

2036

140823

Gene nameerythrocyte membrane protein band 4.1 like 1reactive oxygen species modulator 1
Synonyms4.1N|MRD11C20orf52|MTGM|MTGMP|bA353C18.2
Cytomap

20q11.23

20q11.22

Type of geneprotein-codingprotein-coding
Descriptionband 4.1-like protein 1neuron-type nonerythroid protein 4.1neuronal protein 4.1reactive oxygen species modulator 1PCM19ROS modulator 1epididymis tissue protein Li 175glyrichinmitochondrial targeting GXXXG proteinmitochondrial targeting GxxxG motif proteinprotein MGR2 homolog
Modification date2020031320200313
UniProtAcc

Q9H4G0

.
Ensembl transtripts involved in fusion geneENST idsENST00000202028, ENST00000338074, 
ENST00000373941, ENST00000373946, 
ENST00000373950, ENST00000441639, 
ENST00000479336, 		ENST00000336695, 
ENST00000374072, ENST00000374077, 
ENST00000374078, ENST00000397416, 
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)* DoF score24 X 23 X 12=66248 X 9 X 4=288
# samples 349
** MAII scorelog2(34/6624*10)=-4.28409602136162
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(9/288*10)=-1.67807190511264
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context (manual curation of fusion genes in FusionPDB)

PubMed: EPB41L1 [Title/Abstract] AND ROMO1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)EPB41L1(34785963)-ROMO1(34287554), # samples:2
Anticipated loss of major functional domain due to fusion event.EPB41L1-ROMO1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
EPB41L1-ROMO1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
EPB41L1-ROMO1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
EPB41L1-ROMO1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
EPB41L1-ROMO1 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
EPB41L1-ROMO1 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneROMO1

GO:0008284

positive regulation of cell proliferation

18313394

TgeneROMO1

GO:0031640

killing of cells of other organism

22083756

TgeneROMO1

GO:0042742

defense response to bacterium

22083756

TgeneROMO1

GO:0050829

defense response to Gram-negative bacterium

22083756

TgeneROMO1

GO:0050830

defense response to Gram-positive bacterium

22083756

TgeneROMO1

GO:0051838

cytolysis by host of symbiont cells

22083756

TgeneROMO1

GO:2000379

positive regulation of reactive oxygen species metabolic process

16842742


check buttonFusion gene breakpoints across EPB41L1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across ROMO1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure


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Fusion Gene Sample Information

check buttonFusion gene information from FusionGDB2.0.
check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4OVTCGA-24-2026-01AEPB41L1chr20

34785963

+ROMO1chr20

34287555

+
ChimerDB4OVTCGA-24-2026-01AEPB41L1chr20

34796268

+ROMO1chr20

34287440

+
ChimerDB4OVTCGA-24-2026EPB41L1chr20

34785963

+ROMO1chr20

34287554

+
ChimerDB4UCECTCGA-B5-A11JEPB41L1chr20

34785963

+ROMO1chr20

34287554

+


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Fusion ORF Analysis


check buttonFusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000202028EPB41L1chr2034785963+ENST00000374078ROMO1chr2034287554+193716191131858581
ENST00000202028EPB41L1chr2034785963+ENST00000374077ROMO1chr2034287554+193716191131858581
ENST00000202028EPB41L1chr2034785963+ENST00000374072ROMO1chr2034287554+195416191131798561
ENST00000202028EPB41L1chr2034785963+ENST00000397416ROMO1chr2034287554+186316191131858581
ENST00000373950EPB41L1chr2034785963+ENST00000374078ROMO1chr2034287554+198416662351905556
ENST00000373950EPB41L1chr2034785963+ENST00000374077ROMO1chr2034287554+198416662351905556
ENST00000373950EPB41L1chr2034785963+ENST00000374072ROMO1chr2034287554+200116662351845536
ENST00000373950EPB41L1chr2034785963+ENST00000397416ROMO1chr2034287554+191016662351905556
ENST00000441639EPB41L1chr2034785963+ENST00000374078ROMO1chr2034287554+1828151041749581
ENST00000441639EPB41L1chr2034785963+ENST00000374077ROMO1chr2034287554+1828151041749581
ENST00000441639EPB41L1chr2034785963+ENST00000374072ROMO1chr2034287554+1845151041689561
ENST00000441639EPB41L1chr2034785963+ENST00000397416ROMO1chr2034287554+1754151041749581
ENST00000373946EPB41L1chr2034785963+ENST00000374078ROMO1chr2034287554+1857153901778592
ENST00000373946EPB41L1chr2034785963+ENST00000374077ROMO1chr2034287554+1857153901778592
ENST00000373946EPB41L1chr2034785963+ENST00000374072ROMO1chr2034287554+1874153901718572
ENST00000373946EPB41L1chr2034785963+ENST00000397416ROMO1chr2034287554+1783153901778592
ENST00000338074EPB41L1chr2034785963+ENST00000374078ROMO1chr2034287554+21471829772068663
ENST00000338074EPB41L1chr2034785963+ENST00000374077ROMO1chr2034287554+21471829772068663
ENST00000338074EPB41L1chr2034785963+ENST00000374072ROMO1chr2034287554+21641829772008643
ENST00000338074EPB41L1chr2034785963+ENST00000397416ROMO1chr2034287554+20731829772068663
ENST00000373941EPB41L1chr2034785963+ENST00000374078ROMO1chr2034287554+1995167701916638
ENST00000373941EPB41L1chr2034785963+ENST00000374077ROMO1chr2034287554+1995167701916638
ENST00000373941EPB41L1chr2034785963+ENST00000374072ROMO1chr2034287554+2012167701856618
ENST00000373941EPB41L1chr2034785963+ENST00000397416ROMO1chr2034287554+1921167701916638
ENST00000202028EPB41L1chr2034785963+ENST00000374078ROMO1chr2034287555+193716191131858581
ENST00000202028EPB41L1chr2034785963+ENST00000374077ROMO1chr2034287555+193716191131858581
ENST00000202028EPB41L1chr2034785963+ENST00000374072ROMO1chr2034287555+195416191131798561
ENST00000202028EPB41L1chr2034785963+ENST00000397416ROMO1chr2034287555+186316191131858581
ENST00000373950EPB41L1chr2034785963+ENST00000374078ROMO1chr2034287555+198416662351905556
ENST00000373950EPB41L1chr2034785963+ENST00000374077ROMO1chr2034287555+198416662351905556
ENST00000373950EPB41L1chr2034785963+ENST00000374072ROMO1chr2034287555+200116662351845536
ENST00000373950EPB41L1chr2034785963+ENST00000397416ROMO1chr2034287555+191016662351905556
ENST00000441639EPB41L1chr2034785963+ENST00000374078ROMO1chr2034287555+1828151041749581
ENST00000441639EPB41L1chr2034785963+ENST00000374077ROMO1chr2034287555+1828151041749581
ENST00000441639EPB41L1chr2034785963+ENST00000374072ROMO1chr2034287555+1845151041689561
ENST00000441639EPB41L1chr2034785963+ENST00000397416ROMO1chr2034287555+1754151041749581
ENST00000373946EPB41L1chr2034785963+ENST00000374078ROMO1chr2034287555+1857153901778592
ENST00000373946EPB41L1chr2034785963+ENST00000374077ROMO1chr2034287555+1857153901778592
ENST00000373946EPB41L1chr2034785963+ENST00000374072ROMO1chr2034287555+1874153901718572
ENST00000373946EPB41L1chr2034785963+ENST00000397416ROMO1chr2034287555+1783153901778592
ENST00000338074EPB41L1chr2034785963+ENST00000374078ROMO1chr2034287555+21471829772068663
ENST00000338074EPB41L1chr2034785963+ENST00000374077ROMO1chr2034287555+21471829772068663
ENST00000338074EPB41L1chr2034785963+ENST00000374072ROMO1chr2034287555+21641829772008643
ENST00000338074EPB41L1chr2034785963+ENST00000397416ROMO1chr2034287555+20731829772068663
ENST00000373941EPB41L1chr2034785963+ENST00000374078ROMO1chr2034287555+1995167701916638
ENST00000373941EPB41L1chr2034785963+ENST00000374077ROMO1chr2034287555+1995167701916638
ENST00000373941EPB41L1chr2034785963+ENST00000374072ROMO1chr2034287555+2012167701856618
ENST00000373941EPB41L1chr2034785963+ENST00000397416ROMO1chr2034287555+1921167701916638

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000202028ENST00000374078EPB41L1chr2034785963+ROMO1chr2034287554+0.0146672240.9853328
ENST00000202028ENST00000374077EPB41L1chr2034785963+ROMO1chr2034287554+0.0146672240.9853328
ENST00000202028ENST00000374072EPB41L1chr2034785963+ROMO1chr2034287554+0.0133894230.9866106
ENST00000202028ENST00000397416EPB41L1chr2034785963+ROMO1chr2034287554+0.0183860250.981614
ENST00000373950ENST00000374078EPB41L1chr2034785963+ROMO1chr2034287554+0.0198717420.9801282
ENST00000373950ENST00000374077EPB41L1chr2034785963+ROMO1chr2034287554+0.0198717420.9801282
ENST00000373950ENST00000374072EPB41L1chr2034785963+ROMO1chr2034287554+0.0186501260.9813498
ENST00000373950ENST00000397416EPB41L1chr2034785963+ROMO1chr2034287554+0.024589130.97541094
ENST00000441639ENST00000374078EPB41L1chr2034785963+ROMO1chr2034287554+0.0147878940.9852121
ENST00000441639ENST00000374077EPB41L1chr2034785963+ROMO1chr2034287554+0.0147878940.9852121
ENST00000441639ENST00000374072EPB41L1chr2034785963+ROMO1chr2034287554+0.0133982440.98660177
ENST00000441639ENST00000397416EPB41L1chr2034785963+ROMO1chr2034287554+0.0185923190.9814077
ENST00000373946ENST00000374078EPB41L1chr2034785963+ROMO1chr2034287554+0.01690250.98309755
ENST00000373946ENST00000374077EPB41L1chr2034785963+ROMO1chr2034287554+0.01690250.98309755
ENST00000373946ENST00000374072EPB41L1chr2034785963+ROMO1chr2034287554+0.0154243130.9845756
ENST00000373946ENST00000397416EPB41L1chr2034785963+ROMO1chr2034287554+0.0207705670.97922945
ENST00000338074ENST00000374078EPB41L1chr2034785963+ROMO1chr2034287554+0.024652470.9753475
ENST00000338074ENST00000374077EPB41L1chr2034785963+ROMO1chr2034287554+0.024652470.9753475
ENST00000338074ENST00000374072EPB41L1chr2034785963+ROMO1chr2034287554+0.0233596120.97664034
ENST00000338074ENST00000397416EPB41L1chr2034785963+ROMO1chr2034287554+0.0286962460.9713038
ENST00000373941ENST00000374078EPB41L1chr2034785963+ROMO1chr2034287554+0.0229510070.97704893
ENST00000373941ENST00000374077EPB41L1chr2034785963+ROMO1chr2034287554+0.0229510070.97704893
ENST00000373941ENST00000374072EPB41L1chr2034785963+ROMO1chr2034287554+0.0216115120.9783885
ENST00000373941ENST00000397416EPB41L1chr2034785963+ROMO1chr2034287554+0.027093050.97290695
ENST00000202028ENST00000374078EPB41L1chr2034785963+ROMO1chr2034287555+0.0146672240.9853328
ENST00000202028ENST00000374077EPB41L1chr2034785963+ROMO1chr2034287555+0.0146672240.9853328
ENST00000202028ENST00000374072EPB41L1chr2034785963+ROMO1chr2034287555+0.0133894230.9866106
ENST00000202028ENST00000397416EPB41L1chr2034785963+ROMO1chr2034287555+0.0183860250.981614
ENST00000373950ENST00000374078EPB41L1chr2034785963+ROMO1chr2034287555+0.0198717420.9801282
ENST00000373950ENST00000374077EPB41L1chr2034785963+ROMO1chr2034287555+0.0198717420.9801282
ENST00000373950ENST00000374072EPB41L1chr2034785963+ROMO1chr2034287555+0.0186501260.9813498
ENST00000373950ENST00000397416EPB41L1chr2034785963+ROMO1chr2034287555+0.024589130.97541094
ENST00000441639ENST00000374078EPB41L1chr2034785963+ROMO1chr2034287555+0.0147878940.9852121
ENST00000441639ENST00000374077EPB41L1chr2034785963+ROMO1chr2034287555+0.0147878940.9852121
ENST00000441639ENST00000374072EPB41L1chr2034785963+ROMO1chr2034287555+0.0133982440.98660177
ENST00000441639ENST00000397416EPB41L1chr2034785963+ROMO1chr2034287555+0.0185923190.9814077
ENST00000373946ENST00000374078EPB41L1chr2034785963+ROMO1chr2034287555+0.01690250.98309755
ENST00000373946ENST00000374077EPB41L1chr2034785963+ROMO1chr2034287555+0.01690250.98309755
ENST00000373946ENST00000374072EPB41L1chr2034785963+ROMO1chr2034287555+0.0154243130.9845756
ENST00000373946ENST00000397416EPB41L1chr2034785963+ROMO1chr2034287555+0.0207705670.97922945
ENST00000338074ENST00000374078EPB41L1chr2034785963+ROMO1chr2034287555+0.024652470.9753475
ENST00000338074ENST00000374077EPB41L1chr2034785963+ROMO1chr2034287555+0.024652470.9753475
ENST00000338074ENST00000374072EPB41L1chr2034785963+ROMO1chr2034287555+0.0233596120.97664034
ENST00000338074ENST00000397416EPB41L1chr2034785963+ROMO1chr2034287555+0.0286962460.9713038
ENST00000373941ENST00000374078EPB41L1chr2034785963+ROMO1chr2034287555+0.0229510070.97704893
ENST00000373941ENST00000374077EPB41L1chr2034785963+ROMO1chr2034287555+0.0229510070.97704893
ENST00000373941ENST00000374072EPB41L1chr2034785963+ROMO1chr2034287555+0.0216115120.9783885
ENST00000373941ENST00000397416EPB41L1chr2034785963+ROMO1chr2034287555+0.027093050.97290695

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Fusion Amino Acid Sequences


check button For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

>26823_26823_1_EPB41L1-ROMO1_EPB41L1_chr20_34785963_ENST00000202028_ROMO1_chr20_34287554_ENST00000374072_length(amino acids)=561AA_BP=502
MTDRSSCPRGAGVDRGGSLDMEEKDYSEADGLSERTTPSKAQKSPQKIAKKYKSAICRVTLLDASEYECEVEKHGRGQVLFDLVCEHLNL
LEKDYFGLTFCDADSQKNWLDPSKEIKKQIRSSPWNFAFTVKFYPPDPAQLTEDITRYYLCLQLRADIITGRLPCSFVTHALLGSYAVQA
ELGDYDAEEHVGNYVSELRFAPNQTRELEERIMELHKTYRGMTPGEAEIHFLENAKKLSMYGVDLHHAKDSEGIDIMLGVCANGLLIYRD
RLRINRFAWPKILKISYKRSNFYIKIRPGEYEQFESTIGFKLPNHRSAKRLWKVCIEHHTFFRLVSPEPPPKGFLVMGSKFRYSGRTQAQ
TRQASALIDRPAPFFERSSSKRYTMSRSLDGAEFSRPASVSENHDAGPDGDKRDEDGESGGQRSEAEEGEVRTPTKIKELKFLDKPEDVL
LKHQASINELKRTLKEPNSKLIHRDRDWERERRLPSSPASPSPKGTPEKANEMPVAVGPYGQSQPSCFDRVKMGFVMGCAVGMAAGALFG

--------------------------------------------------------------

>26823_26823_2_EPB41L1-ROMO1_EPB41L1_chr20_34785963_ENST00000202028_ROMO1_chr20_34287554_ENST00000374077_length(amino acids)=581AA_BP=502
MTDRSSCPRGAGVDRGGSLDMEEKDYSEADGLSERTTPSKAQKSPQKIAKKYKSAICRVTLLDASEYECEVEKHGRGQVLFDLVCEHLNL
LEKDYFGLTFCDADSQKNWLDPSKEIKKQIRSSPWNFAFTVKFYPPDPAQLTEDITRYYLCLQLRADIITGRLPCSFVTHALLGSYAVQA
ELGDYDAEEHVGNYVSELRFAPNQTRELEERIMELHKTYRGMTPGEAEIHFLENAKKLSMYGVDLHHAKDSEGIDIMLGVCANGLLIYRD
RLRINRFAWPKILKISYKRSNFYIKIRPGEYEQFESTIGFKLPNHRSAKRLWKVCIEHHTFFRLVSPEPPPKGFLVMGSKFRYSGRTQAQ
TRQASALIDRPAPFFERSSSKRYTMSRSLDGAEFSRPASVSENHDAGPDGDKRDEDGESGGQRSEAEEGEVRTPTKIKELKFLDKPEDVL
LKHQASINELKRTLKEPNSKLIHRDRDWERERRLPSSPASPSPKGTPEKANEMPVAVGPYGQSQPSCFDRVKMGFVMGCAVGMAAGALFG

--------------------------------------------------------------

>26823_26823_3_EPB41L1-ROMO1_EPB41L1_chr20_34785963_ENST00000202028_ROMO1_chr20_34287554_ENST00000374078_length(amino acids)=581AA_BP=502
MTDRSSCPRGAGVDRGGSLDMEEKDYSEADGLSERTTPSKAQKSPQKIAKKYKSAICRVTLLDASEYECEVEKHGRGQVLFDLVCEHLNL
LEKDYFGLTFCDADSQKNWLDPSKEIKKQIRSSPWNFAFTVKFYPPDPAQLTEDITRYYLCLQLRADIITGRLPCSFVTHALLGSYAVQA
ELGDYDAEEHVGNYVSELRFAPNQTRELEERIMELHKTYRGMTPGEAEIHFLENAKKLSMYGVDLHHAKDSEGIDIMLGVCANGLLIYRD
RLRINRFAWPKILKISYKRSNFYIKIRPGEYEQFESTIGFKLPNHRSAKRLWKVCIEHHTFFRLVSPEPPPKGFLVMGSKFRYSGRTQAQ
TRQASALIDRPAPFFERSSSKRYTMSRSLDGAEFSRPASVSENHDAGPDGDKRDEDGESGGQRSEAEEGEVRTPTKIKELKFLDKPEDVL
LKHQASINELKRTLKEPNSKLIHRDRDWERERRLPSSPASPSPKGTPEKANEMPVAVGPYGQSQPSCFDRVKMGFVMGCAVGMAAGALFG

--------------------------------------------------------------

>26823_26823_4_EPB41L1-ROMO1_EPB41L1_chr20_34785963_ENST00000202028_ROMO1_chr20_34287554_ENST00000397416_length(amino acids)=581AA_BP=502
MTDRSSCPRGAGVDRGGSLDMEEKDYSEADGLSERTTPSKAQKSPQKIAKKYKSAICRVTLLDASEYECEVEKHGRGQVLFDLVCEHLNL
LEKDYFGLTFCDADSQKNWLDPSKEIKKQIRSSPWNFAFTVKFYPPDPAQLTEDITRYYLCLQLRADIITGRLPCSFVTHALLGSYAVQA
ELGDYDAEEHVGNYVSELRFAPNQTRELEERIMELHKTYRGMTPGEAEIHFLENAKKLSMYGVDLHHAKDSEGIDIMLGVCANGLLIYRD
RLRINRFAWPKILKISYKRSNFYIKIRPGEYEQFESTIGFKLPNHRSAKRLWKVCIEHHTFFRLVSPEPPPKGFLVMGSKFRYSGRTQAQ
TRQASALIDRPAPFFERSSSKRYTMSRSLDGAEFSRPASVSENHDAGPDGDKRDEDGESGGQRSEAEEGEVRTPTKIKELKFLDKPEDVL
LKHQASINELKRTLKEPNSKLIHRDRDWERERRLPSSPASPSPKGTPEKANEMPVAVGPYGQSQPSCFDRVKMGFVMGCAVGMAAGALFG

--------------------------------------------------------------

>26823_26823_5_EPB41L1-ROMO1_EPB41L1_chr20_34785963_ENST00000202028_ROMO1_chr20_34287555_ENST00000374072_length(amino acids)=561AA_BP=502
MTDRSSCPRGAGVDRGGSLDMEEKDYSEADGLSERTTPSKAQKSPQKIAKKYKSAICRVTLLDASEYECEVEKHGRGQVLFDLVCEHLNL
LEKDYFGLTFCDADSQKNWLDPSKEIKKQIRSSPWNFAFTVKFYPPDPAQLTEDITRYYLCLQLRADIITGRLPCSFVTHALLGSYAVQA
ELGDYDAEEHVGNYVSELRFAPNQTRELEERIMELHKTYRGMTPGEAEIHFLENAKKLSMYGVDLHHAKDSEGIDIMLGVCANGLLIYRD
RLRINRFAWPKILKISYKRSNFYIKIRPGEYEQFESTIGFKLPNHRSAKRLWKVCIEHHTFFRLVSPEPPPKGFLVMGSKFRYSGRTQAQ
TRQASALIDRPAPFFERSSSKRYTMSRSLDGAEFSRPASVSENHDAGPDGDKRDEDGESGGQRSEAEEGEVRTPTKIKELKFLDKPEDVL
LKHQASINELKRTLKEPNSKLIHRDRDWERERRLPSSPASPSPKGTPEKANEMPVAVGPYGQSQPSCFDRVKMGFVMGCAVGMAAGALFG

--------------------------------------------------------------

>26823_26823_6_EPB41L1-ROMO1_EPB41L1_chr20_34785963_ENST00000202028_ROMO1_chr20_34287555_ENST00000374077_length(amino acids)=581AA_BP=502
MTDRSSCPRGAGVDRGGSLDMEEKDYSEADGLSERTTPSKAQKSPQKIAKKYKSAICRVTLLDASEYECEVEKHGRGQVLFDLVCEHLNL
LEKDYFGLTFCDADSQKNWLDPSKEIKKQIRSSPWNFAFTVKFYPPDPAQLTEDITRYYLCLQLRADIITGRLPCSFVTHALLGSYAVQA
ELGDYDAEEHVGNYVSELRFAPNQTRELEERIMELHKTYRGMTPGEAEIHFLENAKKLSMYGVDLHHAKDSEGIDIMLGVCANGLLIYRD
RLRINRFAWPKILKISYKRSNFYIKIRPGEYEQFESTIGFKLPNHRSAKRLWKVCIEHHTFFRLVSPEPPPKGFLVMGSKFRYSGRTQAQ
TRQASALIDRPAPFFERSSSKRYTMSRSLDGAEFSRPASVSENHDAGPDGDKRDEDGESGGQRSEAEEGEVRTPTKIKELKFLDKPEDVL
LKHQASINELKRTLKEPNSKLIHRDRDWERERRLPSSPASPSPKGTPEKANEMPVAVGPYGQSQPSCFDRVKMGFVMGCAVGMAAGALFG

--------------------------------------------------------------

>26823_26823_7_EPB41L1-ROMO1_EPB41L1_chr20_34785963_ENST00000202028_ROMO1_chr20_34287555_ENST00000374078_length(amino acids)=581AA_BP=502
MTDRSSCPRGAGVDRGGSLDMEEKDYSEADGLSERTTPSKAQKSPQKIAKKYKSAICRVTLLDASEYECEVEKHGRGQVLFDLVCEHLNL
LEKDYFGLTFCDADSQKNWLDPSKEIKKQIRSSPWNFAFTVKFYPPDPAQLTEDITRYYLCLQLRADIITGRLPCSFVTHALLGSYAVQA
ELGDYDAEEHVGNYVSELRFAPNQTRELEERIMELHKTYRGMTPGEAEIHFLENAKKLSMYGVDLHHAKDSEGIDIMLGVCANGLLIYRD
RLRINRFAWPKILKISYKRSNFYIKIRPGEYEQFESTIGFKLPNHRSAKRLWKVCIEHHTFFRLVSPEPPPKGFLVMGSKFRYSGRTQAQ
TRQASALIDRPAPFFERSSSKRYTMSRSLDGAEFSRPASVSENHDAGPDGDKRDEDGESGGQRSEAEEGEVRTPTKIKELKFLDKPEDVL
LKHQASINELKRTLKEPNSKLIHRDRDWERERRLPSSPASPSPKGTPEKANEMPVAVGPYGQSQPSCFDRVKMGFVMGCAVGMAAGALFG

--------------------------------------------------------------

>26823_26823_8_EPB41L1-ROMO1_EPB41L1_chr20_34785963_ENST00000202028_ROMO1_chr20_34287555_ENST00000397416_length(amino acids)=581AA_BP=502
MTDRSSCPRGAGVDRGGSLDMEEKDYSEADGLSERTTPSKAQKSPQKIAKKYKSAICRVTLLDASEYECEVEKHGRGQVLFDLVCEHLNL
LEKDYFGLTFCDADSQKNWLDPSKEIKKQIRSSPWNFAFTVKFYPPDPAQLTEDITRYYLCLQLRADIITGRLPCSFVTHALLGSYAVQA
ELGDYDAEEHVGNYVSELRFAPNQTRELEERIMELHKTYRGMTPGEAEIHFLENAKKLSMYGVDLHHAKDSEGIDIMLGVCANGLLIYRD
RLRINRFAWPKILKISYKRSNFYIKIRPGEYEQFESTIGFKLPNHRSAKRLWKVCIEHHTFFRLVSPEPPPKGFLVMGSKFRYSGRTQAQ
TRQASALIDRPAPFFERSSSKRYTMSRSLDGAEFSRPASVSENHDAGPDGDKRDEDGESGGQRSEAEEGEVRTPTKIKELKFLDKPEDVL
LKHQASINELKRTLKEPNSKLIHRDRDWERERRLPSSPASPSPKGTPEKANEMPVAVGPYGQSQPSCFDRVKMGFVMGCAVGMAAGALFG

--------------------------------------------------------------

>26823_26823_9_EPB41L1-ROMO1_EPB41L1_chr20_34785963_ENST00000338074_ROMO1_chr20_34287554_ENST00000374072_length(amino acids)=643AA_BP=584
MPARGAEGAAPRPTCPTWGTPGPGVLVTMTTETGPDSEVKKAQEEAPQQPEAAAAVTTPVTPAGHGHPEANSNEKHPSQQDTRPAEQSLD
MEEKDYSEADGLSERTTPSKAQKSPQKIAKKYKSAICRVTLLDASEYECEVEKHGRGQVLFDLVCEHLNLLEKDYFGLTFCDADSQKNWL
DPSKEIKKQIRSSPWNFAFTVKFYPPDPAQLTEDITRYYLCLQLRADIITGRLPCSFVTHALLGSYAVQAELGDYDAEEHVGNYVSELRF
APNQTRELEERIMELHKTYRGMTPGEAEIHFLENAKKLSMYGVDLHHAKDSEGIDIMLGVCANGLLIYRDRLRINRFAWPKILKISYKRS
NFYIKIRPGEYEQFESTIGFKLPNHRSAKRLWKVCIEHHTFFRLVSPEPPPKGFLVMGSKFRYSGRTQAQTRQASALIDRPAPFFERSSS
KRYTMSRSLDGAEFSRPASVSENHDAGPDGDKRDEDGESGGQRSEAEEGEVRTPTKIKELKPEQETTPRHKQEFLDKPEDVLLKHQASIN
ELKRTLKEPNSKLIHRDRDWERERRLPSSPASPSPKGTPEKANEMPVAVGPYGQSQPSCFDRVKMGFVMGCAVGMAAGALFGTFSCLSSI

--------------------------------------------------------------

>26823_26823_10_EPB41L1-ROMO1_EPB41L1_chr20_34785963_ENST00000338074_ROMO1_chr20_34287554_ENST00000374077_length(amino acids)=663AA_BP=584
MPARGAEGAAPRPTCPTWGTPGPGVLVTMTTETGPDSEVKKAQEEAPQQPEAAAAVTTPVTPAGHGHPEANSNEKHPSQQDTRPAEQSLD
MEEKDYSEADGLSERTTPSKAQKSPQKIAKKYKSAICRVTLLDASEYECEVEKHGRGQVLFDLVCEHLNLLEKDYFGLTFCDADSQKNWL
DPSKEIKKQIRSSPWNFAFTVKFYPPDPAQLTEDITRYYLCLQLRADIITGRLPCSFVTHALLGSYAVQAELGDYDAEEHVGNYVSELRF
APNQTRELEERIMELHKTYRGMTPGEAEIHFLENAKKLSMYGVDLHHAKDSEGIDIMLGVCANGLLIYRDRLRINRFAWPKILKISYKRS
NFYIKIRPGEYEQFESTIGFKLPNHRSAKRLWKVCIEHHTFFRLVSPEPPPKGFLVMGSKFRYSGRTQAQTRQASALIDRPAPFFERSSS
KRYTMSRSLDGAEFSRPASVSENHDAGPDGDKRDEDGESGGQRSEAEEGEVRTPTKIKELKPEQETTPRHKQEFLDKPEDVLLKHQASIN
ELKRTLKEPNSKLIHRDRDWERERRLPSSPASPSPKGTPEKANEMPVAVGPYGQSQPSCFDRVKMGFVMGCAVGMAAGALFGTFSCLRIG

--------------------------------------------------------------

>26823_26823_11_EPB41L1-ROMO1_EPB41L1_chr20_34785963_ENST00000338074_ROMO1_chr20_34287554_ENST00000374078_length(amino acids)=663AA_BP=584
MPARGAEGAAPRPTCPTWGTPGPGVLVTMTTETGPDSEVKKAQEEAPQQPEAAAAVTTPVTPAGHGHPEANSNEKHPSQQDTRPAEQSLD
MEEKDYSEADGLSERTTPSKAQKSPQKIAKKYKSAICRVTLLDASEYECEVEKHGRGQVLFDLVCEHLNLLEKDYFGLTFCDADSQKNWL
DPSKEIKKQIRSSPWNFAFTVKFYPPDPAQLTEDITRYYLCLQLRADIITGRLPCSFVTHALLGSYAVQAELGDYDAEEHVGNYVSELRF
APNQTRELEERIMELHKTYRGMTPGEAEIHFLENAKKLSMYGVDLHHAKDSEGIDIMLGVCANGLLIYRDRLRINRFAWPKILKISYKRS
NFYIKIRPGEYEQFESTIGFKLPNHRSAKRLWKVCIEHHTFFRLVSPEPPPKGFLVMGSKFRYSGRTQAQTRQASALIDRPAPFFERSSS
KRYTMSRSLDGAEFSRPASVSENHDAGPDGDKRDEDGESGGQRSEAEEGEVRTPTKIKELKPEQETTPRHKQEFLDKPEDVLLKHQASIN
ELKRTLKEPNSKLIHRDRDWERERRLPSSPASPSPKGTPEKANEMPVAVGPYGQSQPSCFDRVKMGFVMGCAVGMAAGALFGTFSCLRIG

--------------------------------------------------------------

>26823_26823_12_EPB41L1-ROMO1_EPB41L1_chr20_34785963_ENST00000338074_ROMO1_chr20_34287554_ENST00000397416_length(amino acids)=663AA_BP=584
MPARGAEGAAPRPTCPTWGTPGPGVLVTMTTETGPDSEVKKAQEEAPQQPEAAAAVTTPVTPAGHGHPEANSNEKHPSQQDTRPAEQSLD
MEEKDYSEADGLSERTTPSKAQKSPQKIAKKYKSAICRVTLLDASEYECEVEKHGRGQVLFDLVCEHLNLLEKDYFGLTFCDADSQKNWL
DPSKEIKKQIRSSPWNFAFTVKFYPPDPAQLTEDITRYYLCLQLRADIITGRLPCSFVTHALLGSYAVQAELGDYDAEEHVGNYVSELRF
APNQTRELEERIMELHKTYRGMTPGEAEIHFLENAKKLSMYGVDLHHAKDSEGIDIMLGVCANGLLIYRDRLRINRFAWPKILKISYKRS
NFYIKIRPGEYEQFESTIGFKLPNHRSAKRLWKVCIEHHTFFRLVSPEPPPKGFLVMGSKFRYSGRTQAQTRQASALIDRPAPFFERSSS
KRYTMSRSLDGAEFSRPASVSENHDAGPDGDKRDEDGESGGQRSEAEEGEVRTPTKIKELKPEQETTPRHKQEFLDKPEDVLLKHQASIN
ELKRTLKEPNSKLIHRDRDWERERRLPSSPASPSPKGTPEKANEMPVAVGPYGQSQPSCFDRVKMGFVMGCAVGMAAGALFGTFSCLRIG

--------------------------------------------------------------

>26823_26823_13_EPB41L1-ROMO1_EPB41L1_chr20_34785963_ENST00000338074_ROMO1_chr20_34287555_ENST00000374072_length(amino acids)=643AA_BP=584
MPARGAEGAAPRPTCPTWGTPGPGVLVTMTTETGPDSEVKKAQEEAPQQPEAAAAVTTPVTPAGHGHPEANSNEKHPSQQDTRPAEQSLD
MEEKDYSEADGLSERTTPSKAQKSPQKIAKKYKSAICRVTLLDASEYECEVEKHGRGQVLFDLVCEHLNLLEKDYFGLTFCDADSQKNWL
DPSKEIKKQIRSSPWNFAFTVKFYPPDPAQLTEDITRYYLCLQLRADIITGRLPCSFVTHALLGSYAVQAELGDYDAEEHVGNYVSELRF
APNQTRELEERIMELHKTYRGMTPGEAEIHFLENAKKLSMYGVDLHHAKDSEGIDIMLGVCANGLLIYRDRLRINRFAWPKILKISYKRS
NFYIKIRPGEYEQFESTIGFKLPNHRSAKRLWKVCIEHHTFFRLVSPEPPPKGFLVMGSKFRYSGRTQAQTRQASALIDRPAPFFERSSS
KRYTMSRSLDGAEFSRPASVSENHDAGPDGDKRDEDGESGGQRSEAEEGEVRTPTKIKELKPEQETTPRHKQEFLDKPEDVLLKHQASIN
ELKRTLKEPNSKLIHRDRDWERERRLPSSPASPSPKGTPEKANEMPVAVGPYGQSQPSCFDRVKMGFVMGCAVGMAAGALFGTFSCLSSI

--------------------------------------------------------------

>26823_26823_14_EPB41L1-ROMO1_EPB41L1_chr20_34785963_ENST00000338074_ROMO1_chr20_34287555_ENST00000374077_length(amino acids)=663AA_BP=584
MPARGAEGAAPRPTCPTWGTPGPGVLVTMTTETGPDSEVKKAQEEAPQQPEAAAAVTTPVTPAGHGHPEANSNEKHPSQQDTRPAEQSLD
MEEKDYSEADGLSERTTPSKAQKSPQKIAKKYKSAICRVTLLDASEYECEVEKHGRGQVLFDLVCEHLNLLEKDYFGLTFCDADSQKNWL
DPSKEIKKQIRSSPWNFAFTVKFYPPDPAQLTEDITRYYLCLQLRADIITGRLPCSFVTHALLGSYAVQAELGDYDAEEHVGNYVSELRF
APNQTRELEERIMELHKTYRGMTPGEAEIHFLENAKKLSMYGVDLHHAKDSEGIDIMLGVCANGLLIYRDRLRINRFAWPKILKISYKRS
NFYIKIRPGEYEQFESTIGFKLPNHRSAKRLWKVCIEHHTFFRLVSPEPPPKGFLVMGSKFRYSGRTQAQTRQASALIDRPAPFFERSSS
KRYTMSRSLDGAEFSRPASVSENHDAGPDGDKRDEDGESGGQRSEAEEGEVRTPTKIKELKPEQETTPRHKQEFLDKPEDVLLKHQASIN
ELKRTLKEPNSKLIHRDRDWERERRLPSSPASPSPKGTPEKANEMPVAVGPYGQSQPSCFDRVKMGFVMGCAVGMAAGALFGTFSCLRIG

--------------------------------------------------------------

>26823_26823_15_EPB41L1-ROMO1_EPB41L1_chr20_34785963_ENST00000338074_ROMO1_chr20_34287555_ENST00000374078_length(amino acids)=663AA_BP=584
MPARGAEGAAPRPTCPTWGTPGPGVLVTMTTETGPDSEVKKAQEEAPQQPEAAAAVTTPVTPAGHGHPEANSNEKHPSQQDTRPAEQSLD
MEEKDYSEADGLSERTTPSKAQKSPQKIAKKYKSAICRVTLLDASEYECEVEKHGRGQVLFDLVCEHLNLLEKDYFGLTFCDADSQKNWL
DPSKEIKKQIRSSPWNFAFTVKFYPPDPAQLTEDITRYYLCLQLRADIITGRLPCSFVTHALLGSYAVQAELGDYDAEEHVGNYVSELRF
APNQTRELEERIMELHKTYRGMTPGEAEIHFLENAKKLSMYGVDLHHAKDSEGIDIMLGVCANGLLIYRDRLRINRFAWPKILKISYKRS
NFYIKIRPGEYEQFESTIGFKLPNHRSAKRLWKVCIEHHTFFRLVSPEPPPKGFLVMGSKFRYSGRTQAQTRQASALIDRPAPFFERSSS
KRYTMSRSLDGAEFSRPASVSENHDAGPDGDKRDEDGESGGQRSEAEEGEVRTPTKIKELKPEQETTPRHKQEFLDKPEDVLLKHQASIN
ELKRTLKEPNSKLIHRDRDWERERRLPSSPASPSPKGTPEKANEMPVAVGPYGQSQPSCFDRVKMGFVMGCAVGMAAGALFGTFSCLRIG

--------------------------------------------------------------

>26823_26823_16_EPB41L1-ROMO1_EPB41L1_chr20_34785963_ENST00000338074_ROMO1_chr20_34287555_ENST00000397416_length(amino acids)=663AA_BP=584
MPARGAEGAAPRPTCPTWGTPGPGVLVTMTTETGPDSEVKKAQEEAPQQPEAAAAVTTPVTPAGHGHPEANSNEKHPSQQDTRPAEQSLD
MEEKDYSEADGLSERTTPSKAQKSPQKIAKKYKSAICRVTLLDASEYECEVEKHGRGQVLFDLVCEHLNLLEKDYFGLTFCDADSQKNWL
DPSKEIKKQIRSSPWNFAFTVKFYPPDPAQLTEDITRYYLCLQLRADIITGRLPCSFVTHALLGSYAVQAELGDYDAEEHVGNYVSELRF
APNQTRELEERIMELHKTYRGMTPGEAEIHFLENAKKLSMYGVDLHHAKDSEGIDIMLGVCANGLLIYRDRLRINRFAWPKILKISYKRS
NFYIKIRPGEYEQFESTIGFKLPNHRSAKRLWKVCIEHHTFFRLVSPEPPPKGFLVMGSKFRYSGRTQAQTRQASALIDRPAPFFERSSS
KRYTMSRSLDGAEFSRPASVSENHDAGPDGDKRDEDGESGGQRSEAEEGEVRTPTKIKELKPEQETTPRHKQEFLDKPEDVLLKHQASIN
ELKRTLKEPNSKLIHRDRDWERERRLPSSPASPSPKGTPEKANEMPVAVGPYGQSQPSCFDRVKMGFVMGCAVGMAAGALFGTFSCLRIG

--------------------------------------------------------------

>26823_26823_17_EPB41L1-ROMO1_EPB41L1_chr20_34785963_ENST00000373941_ROMO1_chr20_34287554_ENST00000374072_length(amino acids)=618AA_BP=559
LVTMTTETGPDSEVKKAQEEAPQQPEAAAAVTTPVTPAGHGHPEANSNEKHPSQQDTRPAEQSLDMEEKDYSEADGLSERTTPSKAQKSP
QKIAKKYKSAICRVTLLDASEYECEVEKHGRGQVLFDLVCEHLNLLEKDYFGLTFCDADSQKNWLDPSKEIKKQIRSSPWNFAFTVKFYP
PDPAQLTEDITRYYLCLQLRADIITGRLPCSFVTHALLGSYAVQAELGDYDAEEHVGNYVSELRFAPNQTRELEERIMELHKTYRGMTPG
EAEIHFLENAKKLSMYGVDLHHAKDSEGIDIMLGVCANGLLIYRDRLRINRFAWPKILKISYKRSNFYIKIRPGEYEQFESTIGFKLPNH
RSAKRLWKVCIEHHTFFRLVSPEPPPKGFLVMGSKFRYSGRTQAQTRQASALIDRPAPFFERSSSKRYTMSRSLDGAEFSRPASVSENHD
AGPDGDKRDEDGESGGQRSEAEEGEVRTPTKIKELKPEQETTPRHKQEFLDKPEDVLLKHQASINELKRTLKEPNSKLIHRDRDWERERR

--------------------------------------------------------------

>26823_26823_18_EPB41L1-ROMO1_EPB41L1_chr20_34785963_ENST00000373941_ROMO1_chr20_34287554_ENST00000374077_length(amino acids)=638AA_BP=559
LVTMTTETGPDSEVKKAQEEAPQQPEAAAAVTTPVTPAGHGHPEANSNEKHPSQQDTRPAEQSLDMEEKDYSEADGLSERTTPSKAQKSP
QKIAKKYKSAICRVTLLDASEYECEVEKHGRGQVLFDLVCEHLNLLEKDYFGLTFCDADSQKNWLDPSKEIKKQIRSSPWNFAFTVKFYP
PDPAQLTEDITRYYLCLQLRADIITGRLPCSFVTHALLGSYAVQAELGDYDAEEHVGNYVSELRFAPNQTRELEERIMELHKTYRGMTPG
EAEIHFLENAKKLSMYGVDLHHAKDSEGIDIMLGVCANGLLIYRDRLRINRFAWPKILKISYKRSNFYIKIRPGEYEQFESTIGFKLPNH
RSAKRLWKVCIEHHTFFRLVSPEPPPKGFLVMGSKFRYSGRTQAQTRQASALIDRPAPFFERSSSKRYTMSRSLDGAEFSRPASVSENHD
AGPDGDKRDEDGESGGQRSEAEEGEVRTPTKIKELKPEQETTPRHKQEFLDKPEDVLLKHQASINELKRTLKEPNSKLIHRDRDWERERR
LPSSPASPSPKGTPEKANEMPVAVGPYGQSQPSCFDRVKMGFVMGCAVGMAAGALFGTFSCLRIGMRGRELMGGIGKTMMQSGGTFGTFM

--------------------------------------------------------------

>26823_26823_19_EPB41L1-ROMO1_EPB41L1_chr20_34785963_ENST00000373941_ROMO1_chr20_34287554_ENST00000374078_length(amino acids)=638AA_BP=559
LVTMTTETGPDSEVKKAQEEAPQQPEAAAAVTTPVTPAGHGHPEANSNEKHPSQQDTRPAEQSLDMEEKDYSEADGLSERTTPSKAQKSP
QKIAKKYKSAICRVTLLDASEYECEVEKHGRGQVLFDLVCEHLNLLEKDYFGLTFCDADSQKNWLDPSKEIKKQIRSSPWNFAFTVKFYP
PDPAQLTEDITRYYLCLQLRADIITGRLPCSFVTHALLGSYAVQAELGDYDAEEHVGNYVSELRFAPNQTRELEERIMELHKTYRGMTPG
EAEIHFLENAKKLSMYGVDLHHAKDSEGIDIMLGVCANGLLIYRDRLRINRFAWPKILKISYKRSNFYIKIRPGEYEQFESTIGFKLPNH
RSAKRLWKVCIEHHTFFRLVSPEPPPKGFLVMGSKFRYSGRTQAQTRQASALIDRPAPFFERSSSKRYTMSRSLDGAEFSRPASVSENHD
AGPDGDKRDEDGESGGQRSEAEEGEVRTPTKIKELKPEQETTPRHKQEFLDKPEDVLLKHQASINELKRTLKEPNSKLIHRDRDWERERR
LPSSPASPSPKGTPEKANEMPVAVGPYGQSQPSCFDRVKMGFVMGCAVGMAAGALFGTFSCLRIGMRGRELMGGIGKTMMQSGGTFGTFM

--------------------------------------------------------------

>26823_26823_20_EPB41L1-ROMO1_EPB41L1_chr20_34785963_ENST00000373941_ROMO1_chr20_34287554_ENST00000397416_length(amino acids)=638AA_BP=559
LVTMTTETGPDSEVKKAQEEAPQQPEAAAAVTTPVTPAGHGHPEANSNEKHPSQQDTRPAEQSLDMEEKDYSEADGLSERTTPSKAQKSP
QKIAKKYKSAICRVTLLDASEYECEVEKHGRGQVLFDLVCEHLNLLEKDYFGLTFCDADSQKNWLDPSKEIKKQIRSSPWNFAFTVKFYP
PDPAQLTEDITRYYLCLQLRADIITGRLPCSFVTHALLGSYAVQAELGDYDAEEHVGNYVSELRFAPNQTRELEERIMELHKTYRGMTPG
EAEIHFLENAKKLSMYGVDLHHAKDSEGIDIMLGVCANGLLIYRDRLRINRFAWPKILKISYKRSNFYIKIRPGEYEQFESTIGFKLPNH
RSAKRLWKVCIEHHTFFRLVSPEPPPKGFLVMGSKFRYSGRTQAQTRQASALIDRPAPFFERSSSKRYTMSRSLDGAEFSRPASVSENHD
AGPDGDKRDEDGESGGQRSEAEEGEVRTPTKIKELKPEQETTPRHKQEFLDKPEDVLLKHQASINELKRTLKEPNSKLIHRDRDWERERR
LPSSPASPSPKGTPEKANEMPVAVGPYGQSQPSCFDRVKMGFVMGCAVGMAAGALFGTFSCLRIGMRGRELMGGIGKTMMQSGGTFGTFM

--------------------------------------------------------------

>26823_26823_21_EPB41L1-ROMO1_EPB41L1_chr20_34785963_ENST00000373941_ROMO1_chr20_34287555_ENST00000374072_length(amino acids)=618AA_BP=559
LVTMTTETGPDSEVKKAQEEAPQQPEAAAAVTTPVTPAGHGHPEANSNEKHPSQQDTRPAEQSLDMEEKDYSEADGLSERTTPSKAQKSP
QKIAKKYKSAICRVTLLDASEYECEVEKHGRGQVLFDLVCEHLNLLEKDYFGLTFCDADSQKNWLDPSKEIKKQIRSSPWNFAFTVKFYP
PDPAQLTEDITRYYLCLQLRADIITGRLPCSFVTHALLGSYAVQAELGDYDAEEHVGNYVSELRFAPNQTRELEERIMELHKTYRGMTPG
EAEIHFLENAKKLSMYGVDLHHAKDSEGIDIMLGVCANGLLIYRDRLRINRFAWPKILKISYKRSNFYIKIRPGEYEQFESTIGFKLPNH
RSAKRLWKVCIEHHTFFRLVSPEPPPKGFLVMGSKFRYSGRTQAQTRQASALIDRPAPFFERSSSKRYTMSRSLDGAEFSRPASVSENHD
AGPDGDKRDEDGESGGQRSEAEEGEVRTPTKIKELKPEQETTPRHKQEFLDKPEDVLLKHQASINELKRTLKEPNSKLIHRDRDWERERR

--------------------------------------------------------------

>26823_26823_22_EPB41L1-ROMO1_EPB41L1_chr20_34785963_ENST00000373941_ROMO1_chr20_34287555_ENST00000374077_length(amino acids)=638AA_BP=559
LVTMTTETGPDSEVKKAQEEAPQQPEAAAAVTTPVTPAGHGHPEANSNEKHPSQQDTRPAEQSLDMEEKDYSEADGLSERTTPSKAQKSP
QKIAKKYKSAICRVTLLDASEYECEVEKHGRGQVLFDLVCEHLNLLEKDYFGLTFCDADSQKNWLDPSKEIKKQIRSSPWNFAFTVKFYP
PDPAQLTEDITRYYLCLQLRADIITGRLPCSFVTHALLGSYAVQAELGDYDAEEHVGNYVSELRFAPNQTRELEERIMELHKTYRGMTPG
EAEIHFLENAKKLSMYGVDLHHAKDSEGIDIMLGVCANGLLIYRDRLRINRFAWPKILKISYKRSNFYIKIRPGEYEQFESTIGFKLPNH
RSAKRLWKVCIEHHTFFRLVSPEPPPKGFLVMGSKFRYSGRTQAQTRQASALIDRPAPFFERSSSKRYTMSRSLDGAEFSRPASVSENHD
AGPDGDKRDEDGESGGQRSEAEEGEVRTPTKIKELKPEQETTPRHKQEFLDKPEDVLLKHQASINELKRTLKEPNSKLIHRDRDWERERR
LPSSPASPSPKGTPEKANEMPVAVGPYGQSQPSCFDRVKMGFVMGCAVGMAAGALFGTFSCLRIGMRGRELMGGIGKTMMQSGGTFGTFM

--------------------------------------------------------------

>26823_26823_23_EPB41L1-ROMO1_EPB41L1_chr20_34785963_ENST00000373941_ROMO1_chr20_34287555_ENST00000374078_length(amino acids)=638AA_BP=559
LVTMTTETGPDSEVKKAQEEAPQQPEAAAAVTTPVTPAGHGHPEANSNEKHPSQQDTRPAEQSLDMEEKDYSEADGLSERTTPSKAQKSP
QKIAKKYKSAICRVTLLDASEYECEVEKHGRGQVLFDLVCEHLNLLEKDYFGLTFCDADSQKNWLDPSKEIKKQIRSSPWNFAFTVKFYP
PDPAQLTEDITRYYLCLQLRADIITGRLPCSFVTHALLGSYAVQAELGDYDAEEHVGNYVSELRFAPNQTRELEERIMELHKTYRGMTPG
EAEIHFLENAKKLSMYGVDLHHAKDSEGIDIMLGVCANGLLIYRDRLRINRFAWPKILKISYKRSNFYIKIRPGEYEQFESTIGFKLPNH
RSAKRLWKVCIEHHTFFRLVSPEPPPKGFLVMGSKFRYSGRTQAQTRQASALIDRPAPFFERSSSKRYTMSRSLDGAEFSRPASVSENHD
AGPDGDKRDEDGESGGQRSEAEEGEVRTPTKIKELKPEQETTPRHKQEFLDKPEDVLLKHQASINELKRTLKEPNSKLIHRDRDWERERR
LPSSPASPSPKGTPEKANEMPVAVGPYGQSQPSCFDRVKMGFVMGCAVGMAAGALFGTFSCLRIGMRGRELMGGIGKTMMQSGGTFGTFM

--------------------------------------------------------------

>26823_26823_24_EPB41L1-ROMO1_EPB41L1_chr20_34785963_ENST00000373941_ROMO1_chr20_34287555_ENST00000397416_length(amino acids)=638AA_BP=559
LVTMTTETGPDSEVKKAQEEAPQQPEAAAAVTTPVTPAGHGHPEANSNEKHPSQQDTRPAEQSLDMEEKDYSEADGLSERTTPSKAQKSP
QKIAKKYKSAICRVTLLDASEYECEVEKHGRGQVLFDLVCEHLNLLEKDYFGLTFCDADSQKNWLDPSKEIKKQIRSSPWNFAFTVKFYP
PDPAQLTEDITRYYLCLQLRADIITGRLPCSFVTHALLGSYAVQAELGDYDAEEHVGNYVSELRFAPNQTRELEERIMELHKTYRGMTPG
EAEIHFLENAKKLSMYGVDLHHAKDSEGIDIMLGVCANGLLIYRDRLRINRFAWPKILKISYKRSNFYIKIRPGEYEQFESTIGFKLPNH
RSAKRLWKVCIEHHTFFRLVSPEPPPKGFLVMGSKFRYSGRTQAQTRQASALIDRPAPFFERSSSKRYTMSRSLDGAEFSRPASVSENHD
AGPDGDKRDEDGESGGQRSEAEEGEVRTPTKIKELKPEQETTPRHKQEFLDKPEDVLLKHQASINELKRTLKEPNSKLIHRDRDWERERR
LPSSPASPSPKGTPEKANEMPVAVGPYGQSQPSCFDRVKMGFVMGCAVGMAAGALFGTFSCLRIGMRGRELMGGIGKTMMQSGGTFGTFM

--------------------------------------------------------------

>26823_26823_25_EPB41L1-ROMO1_EPB41L1_chr20_34785963_ENST00000373946_ROMO1_chr20_34287554_ENST00000374072_length(amino acids)=572AA_BP=513
MVFLGRINEVEPAKGLAESLAPTERSVKSLDMEEKDYSEADGLSERTTPSKAQKSPQKIAKKYKSAICRVTLLDASEYECEVEKHGRGQV
LFDLVCEHLNLLEKDYFGLTFCDADSQKNWLDPSKEIKKQIRSSPWNFAFTVKFYPPDPAQLTEDITRYYLCLQLRADIITGRLPCSFVT
HALLGSYAVQAELGDYDAEEHVGNYVSELRFAPNQTRELEERIMELHKTYRGMTPGEAEIHFLENAKKLSMYGVDLHHAKDSEGIDIMLG
VCANGLLIYRDRLRINRFAWPKILKISYKRSNFYIKIRPGEYEQFESTIGFKLPNHRSAKRLWKVCIEHHTFFRLVSPEPPPKGFLVMGS
KFRYSGRTQAQTRQASALIDRPAPFFERSSSKRYTMSRSLDGAEFSRPASVSENHDAGPDGDKRDEDGESGGQRSEAEEGEVRTPTKIKE
LKFLDKPEDVLLKHQASINELKRTLKEPNSKLIHRDRDWERERRLPSSPASPSPKGTPEKANEMPVAVGPYGQSQPSCFDRVKMGFVMGC

--------------------------------------------------------------

>26823_26823_26_EPB41L1-ROMO1_EPB41L1_chr20_34785963_ENST00000373946_ROMO1_chr20_34287554_ENST00000374077_length(amino acids)=592AA_BP=513
MVFLGRINEVEPAKGLAESLAPTERSVKSLDMEEKDYSEADGLSERTTPSKAQKSPQKIAKKYKSAICRVTLLDASEYECEVEKHGRGQV
LFDLVCEHLNLLEKDYFGLTFCDADSQKNWLDPSKEIKKQIRSSPWNFAFTVKFYPPDPAQLTEDITRYYLCLQLRADIITGRLPCSFVT
HALLGSYAVQAELGDYDAEEHVGNYVSELRFAPNQTRELEERIMELHKTYRGMTPGEAEIHFLENAKKLSMYGVDLHHAKDSEGIDIMLG
VCANGLLIYRDRLRINRFAWPKILKISYKRSNFYIKIRPGEYEQFESTIGFKLPNHRSAKRLWKVCIEHHTFFRLVSPEPPPKGFLVMGS
KFRYSGRTQAQTRQASALIDRPAPFFERSSSKRYTMSRSLDGAEFSRPASVSENHDAGPDGDKRDEDGESGGQRSEAEEGEVRTPTKIKE
LKFLDKPEDVLLKHQASINELKRTLKEPNSKLIHRDRDWERERRLPSSPASPSPKGTPEKANEMPVAVGPYGQSQPSCFDRVKMGFVMGC

--------------------------------------------------------------

>26823_26823_27_EPB41L1-ROMO1_EPB41L1_chr20_34785963_ENST00000373946_ROMO1_chr20_34287554_ENST00000374078_length(amino acids)=592AA_BP=513
MVFLGRINEVEPAKGLAESLAPTERSVKSLDMEEKDYSEADGLSERTTPSKAQKSPQKIAKKYKSAICRVTLLDASEYECEVEKHGRGQV
LFDLVCEHLNLLEKDYFGLTFCDADSQKNWLDPSKEIKKQIRSSPWNFAFTVKFYPPDPAQLTEDITRYYLCLQLRADIITGRLPCSFVT
HALLGSYAVQAELGDYDAEEHVGNYVSELRFAPNQTRELEERIMELHKTYRGMTPGEAEIHFLENAKKLSMYGVDLHHAKDSEGIDIMLG
VCANGLLIYRDRLRINRFAWPKILKISYKRSNFYIKIRPGEYEQFESTIGFKLPNHRSAKRLWKVCIEHHTFFRLVSPEPPPKGFLVMGS
KFRYSGRTQAQTRQASALIDRPAPFFERSSSKRYTMSRSLDGAEFSRPASVSENHDAGPDGDKRDEDGESGGQRSEAEEGEVRTPTKIKE
LKFLDKPEDVLLKHQASINELKRTLKEPNSKLIHRDRDWERERRLPSSPASPSPKGTPEKANEMPVAVGPYGQSQPSCFDRVKMGFVMGC

--------------------------------------------------------------

>26823_26823_28_EPB41L1-ROMO1_EPB41L1_chr20_34785963_ENST00000373946_ROMO1_chr20_34287554_ENST00000397416_length(amino acids)=592AA_BP=513
MVFLGRINEVEPAKGLAESLAPTERSVKSLDMEEKDYSEADGLSERTTPSKAQKSPQKIAKKYKSAICRVTLLDASEYECEVEKHGRGQV
LFDLVCEHLNLLEKDYFGLTFCDADSQKNWLDPSKEIKKQIRSSPWNFAFTVKFYPPDPAQLTEDITRYYLCLQLRADIITGRLPCSFVT
HALLGSYAVQAELGDYDAEEHVGNYVSELRFAPNQTRELEERIMELHKTYRGMTPGEAEIHFLENAKKLSMYGVDLHHAKDSEGIDIMLG
VCANGLLIYRDRLRINRFAWPKILKISYKRSNFYIKIRPGEYEQFESTIGFKLPNHRSAKRLWKVCIEHHTFFRLVSPEPPPKGFLVMGS
KFRYSGRTQAQTRQASALIDRPAPFFERSSSKRYTMSRSLDGAEFSRPASVSENHDAGPDGDKRDEDGESGGQRSEAEEGEVRTPTKIKE
LKFLDKPEDVLLKHQASINELKRTLKEPNSKLIHRDRDWERERRLPSSPASPSPKGTPEKANEMPVAVGPYGQSQPSCFDRVKMGFVMGC

--------------------------------------------------------------

>26823_26823_29_EPB41L1-ROMO1_EPB41L1_chr20_34785963_ENST00000373946_ROMO1_chr20_34287555_ENST00000374072_length(amino acids)=572AA_BP=513
MVFLGRINEVEPAKGLAESLAPTERSVKSLDMEEKDYSEADGLSERTTPSKAQKSPQKIAKKYKSAICRVTLLDASEYECEVEKHGRGQV
LFDLVCEHLNLLEKDYFGLTFCDADSQKNWLDPSKEIKKQIRSSPWNFAFTVKFYPPDPAQLTEDITRYYLCLQLRADIITGRLPCSFVT
HALLGSYAVQAELGDYDAEEHVGNYVSELRFAPNQTRELEERIMELHKTYRGMTPGEAEIHFLENAKKLSMYGVDLHHAKDSEGIDIMLG
VCANGLLIYRDRLRINRFAWPKILKISYKRSNFYIKIRPGEYEQFESTIGFKLPNHRSAKRLWKVCIEHHTFFRLVSPEPPPKGFLVMGS
KFRYSGRTQAQTRQASALIDRPAPFFERSSSKRYTMSRSLDGAEFSRPASVSENHDAGPDGDKRDEDGESGGQRSEAEEGEVRTPTKIKE
LKFLDKPEDVLLKHQASINELKRTLKEPNSKLIHRDRDWERERRLPSSPASPSPKGTPEKANEMPVAVGPYGQSQPSCFDRVKMGFVMGC

--------------------------------------------------------------

>26823_26823_30_EPB41L1-ROMO1_EPB41L1_chr20_34785963_ENST00000373946_ROMO1_chr20_34287555_ENST00000374077_length(amino acids)=592AA_BP=513
MVFLGRINEVEPAKGLAESLAPTERSVKSLDMEEKDYSEADGLSERTTPSKAQKSPQKIAKKYKSAICRVTLLDASEYECEVEKHGRGQV
LFDLVCEHLNLLEKDYFGLTFCDADSQKNWLDPSKEIKKQIRSSPWNFAFTVKFYPPDPAQLTEDITRYYLCLQLRADIITGRLPCSFVT
HALLGSYAVQAELGDYDAEEHVGNYVSELRFAPNQTRELEERIMELHKTYRGMTPGEAEIHFLENAKKLSMYGVDLHHAKDSEGIDIMLG
VCANGLLIYRDRLRINRFAWPKILKISYKRSNFYIKIRPGEYEQFESTIGFKLPNHRSAKRLWKVCIEHHTFFRLVSPEPPPKGFLVMGS
KFRYSGRTQAQTRQASALIDRPAPFFERSSSKRYTMSRSLDGAEFSRPASVSENHDAGPDGDKRDEDGESGGQRSEAEEGEVRTPTKIKE
LKFLDKPEDVLLKHQASINELKRTLKEPNSKLIHRDRDWERERRLPSSPASPSPKGTPEKANEMPVAVGPYGQSQPSCFDRVKMGFVMGC

--------------------------------------------------------------

>26823_26823_31_EPB41L1-ROMO1_EPB41L1_chr20_34785963_ENST00000373946_ROMO1_chr20_34287555_ENST00000374078_length(amino acids)=592AA_BP=513
MVFLGRINEVEPAKGLAESLAPTERSVKSLDMEEKDYSEADGLSERTTPSKAQKSPQKIAKKYKSAICRVTLLDASEYECEVEKHGRGQV
LFDLVCEHLNLLEKDYFGLTFCDADSQKNWLDPSKEIKKQIRSSPWNFAFTVKFYPPDPAQLTEDITRYYLCLQLRADIITGRLPCSFVT
HALLGSYAVQAELGDYDAEEHVGNYVSELRFAPNQTRELEERIMELHKTYRGMTPGEAEIHFLENAKKLSMYGVDLHHAKDSEGIDIMLG
VCANGLLIYRDRLRINRFAWPKILKISYKRSNFYIKIRPGEYEQFESTIGFKLPNHRSAKRLWKVCIEHHTFFRLVSPEPPPKGFLVMGS
KFRYSGRTQAQTRQASALIDRPAPFFERSSSKRYTMSRSLDGAEFSRPASVSENHDAGPDGDKRDEDGESGGQRSEAEEGEVRTPTKIKE
LKFLDKPEDVLLKHQASINELKRTLKEPNSKLIHRDRDWERERRLPSSPASPSPKGTPEKANEMPVAVGPYGQSQPSCFDRVKMGFVMGC

--------------------------------------------------------------

>26823_26823_32_EPB41L1-ROMO1_EPB41L1_chr20_34785963_ENST00000373946_ROMO1_chr20_34287555_ENST00000397416_length(amino acids)=592AA_BP=513
MVFLGRINEVEPAKGLAESLAPTERSVKSLDMEEKDYSEADGLSERTTPSKAQKSPQKIAKKYKSAICRVTLLDASEYECEVEKHGRGQV
LFDLVCEHLNLLEKDYFGLTFCDADSQKNWLDPSKEIKKQIRSSPWNFAFTVKFYPPDPAQLTEDITRYYLCLQLRADIITGRLPCSFVT
HALLGSYAVQAELGDYDAEEHVGNYVSELRFAPNQTRELEERIMELHKTYRGMTPGEAEIHFLENAKKLSMYGVDLHHAKDSEGIDIMLG
VCANGLLIYRDRLRINRFAWPKILKISYKRSNFYIKIRPGEYEQFESTIGFKLPNHRSAKRLWKVCIEHHTFFRLVSPEPPPKGFLVMGS
KFRYSGRTQAQTRQASALIDRPAPFFERSSSKRYTMSRSLDGAEFSRPASVSENHDAGPDGDKRDEDGESGGQRSEAEEGEVRTPTKIKE
LKFLDKPEDVLLKHQASINELKRTLKEPNSKLIHRDRDWERERRLPSSPASPSPKGTPEKANEMPVAVGPYGQSQPSCFDRVKMGFVMGC

--------------------------------------------------------------

>26823_26823_33_EPB41L1-ROMO1_EPB41L1_chr20_34785963_ENST00000373950_ROMO1_chr20_34287554_ENST00000374072_length(amino acids)=536AA_BP=477
MRADGTGSSKADPDTEARPVQQGPHTLSLDMEEKDYSEADGLSERTTPSKAQKSPQKIAKKYKSAICRVTLLDASEYECEVENWLDPSKE
IKKQIRSSPWNFAFTVKFYPPDPAQLTEDITRYYLCLQLRADIITGRLPCSFVTHALLGSYAVQAELGDYDAEEHVGNYVSELRFAPNQT
RELEERIMELHKTYRGMTPGEAEIHFLENAKKLSMYGVDLHHAKDSEGIDIMLGVCANGLLIYRDRLRINRFAWPKILKISYKRSNFYIK
IRPGEYEQFESTIGFKLPNHRSAKRLWKVCIEHHTFFRLVSPEPPPKGFLVMGSKFRYSGRTQAQTRQASALIDRPAPFFERSSSKRYTM
SRSLDGAEFSRPASVSENHDAGPDGDKRDEDGESGGQRSEAEEGEVRTPTKIKELKFLDKPEDVLLKHQASINELKRTLKEPNSKLIHRD

--------------------------------------------------------------

>26823_26823_34_EPB41L1-ROMO1_EPB41L1_chr20_34785963_ENST00000373950_ROMO1_chr20_34287554_ENST00000374077_length(amino acids)=556AA_BP=477
MRADGTGSSKADPDTEARPVQQGPHTLSLDMEEKDYSEADGLSERTTPSKAQKSPQKIAKKYKSAICRVTLLDASEYECEVENWLDPSKE
IKKQIRSSPWNFAFTVKFYPPDPAQLTEDITRYYLCLQLRADIITGRLPCSFVTHALLGSYAVQAELGDYDAEEHVGNYVSELRFAPNQT
RELEERIMELHKTYRGMTPGEAEIHFLENAKKLSMYGVDLHHAKDSEGIDIMLGVCANGLLIYRDRLRINRFAWPKILKISYKRSNFYIK
IRPGEYEQFESTIGFKLPNHRSAKRLWKVCIEHHTFFRLVSPEPPPKGFLVMGSKFRYSGRTQAQTRQASALIDRPAPFFERSSSKRYTM
SRSLDGAEFSRPASVSENHDAGPDGDKRDEDGESGGQRSEAEEGEVRTPTKIKELKFLDKPEDVLLKHQASINELKRTLKEPNSKLIHRD
RDWERERRLPSSPASPSPKGTPEKANEMPVAVGPYGQSQPSCFDRVKMGFVMGCAVGMAAGALFGTFSCLRIGMRGRELMGGIGKTMMQS

--------------------------------------------------------------

>26823_26823_35_EPB41L1-ROMO1_EPB41L1_chr20_34785963_ENST00000373950_ROMO1_chr20_34287554_ENST00000374078_length(amino acids)=556AA_BP=477
MRADGTGSSKADPDTEARPVQQGPHTLSLDMEEKDYSEADGLSERTTPSKAQKSPQKIAKKYKSAICRVTLLDASEYECEVENWLDPSKE
IKKQIRSSPWNFAFTVKFYPPDPAQLTEDITRYYLCLQLRADIITGRLPCSFVTHALLGSYAVQAELGDYDAEEHVGNYVSELRFAPNQT
RELEERIMELHKTYRGMTPGEAEIHFLENAKKLSMYGVDLHHAKDSEGIDIMLGVCANGLLIYRDRLRINRFAWPKILKISYKRSNFYIK
IRPGEYEQFESTIGFKLPNHRSAKRLWKVCIEHHTFFRLVSPEPPPKGFLVMGSKFRYSGRTQAQTRQASALIDRPAPFFERSSSKRYTM
SRSLDGAEFSRPASVSENHDAGPDGDKRDEDGESGGQRSEAEEGEVRTPTKIKELKFLDKPEDVLLKHQASINELKRTLKEPNSKLIHRD
RDWERERRLPSSPASPSPKGTPEKANEMPVAVGPYGQSQPSCFDRVKMGFVMGCAVGMAAGALFGTFSCLRIGMRGRELMGGIGKTMMQS

--------------------------------------------------------------

>26823_26823_36_EPB41L1-ROMO1_EPB41L1_chr20_34785963_ENST00000373950_ROMO1_chr20_34287554_ENST00000397416_length(amino acids)=556AA_BP=477
MRADGTGSSKADPDTEARPVQQGPHTLSLDMEEKDYSEADGLSERTTPSKAQKSPQKIAKKYKSAICRVTLLDASEYECEVENWLDPSKE
IKKQIRSSPWNFAFTVKFYPPDPAQLTEDITRYYLCLQLRADIITGRLPCSFVTHALLGSYAVQAELGDYDAEEHVGNYVSELRFAPNQT
RELEERIMELHKTYRGMTPGEAEIHFLENAKKLSMYGVDLHHAKDSEGIDIMLGVCANGLLIYRDRLRINRFAWPKILKISYKRSNFYIK
IRPGEYEQFESTIGFKLPNHRSAKRLWKVCIEHHTFFRLVSPEPPPKGFLVMGSKFRYSGRTQAQTRQASALIDRPAPFFERSSSKRYTM
SRSLDGAEFSRPASVSENHDAGPDGDKRDEDGESGGQRSEAEEGEVRTPTKIKELKFLDKPEDVLLKHQASINELKRTLKEPNSKLIHRD
RDWERERRLPSSPASPSPKGTPEKANEMPVAVGPYGQSQPSCFDRVKMGFVMGCAVGMAAGALFGTFSCLRIGMRGRELMGGIGKTMMQS

--------------------------------------------------------------

>26823_26823_37_EPB41L1-ROMO1_EPB41L1_chr20_34785963_ENST00000373950_ROMO1_chr20_34287555_ENST00000374072_length(amino acids)=536AA_BP=477
MRADGTGSSKADPDTEARPVQQGPHTLSLDMEEKDYSEADGLSERTTPSKAQKSPQKIAKKYKSAICRVTLLDASEYECEVENWLDPSKE
IKKQIRSSPWNFAFTVKFYPPDPAQLTEDITRYYLCLQLRADIITGRLPCSFVTHALLGSYAVQAELGDYDAEEHVGNYVSELRFAPNQT
RELEERIMELHKTYRGMTPGEAEIHFLENAKKLSMYGVDLHHAKDSEGIDIMLGVCANGLLIYRDRLRINRFAWPKILKISYKRSNFYIK
IRPGEYEQFESTIGFKLPNHRSAKRLWKVCIEHHTFFRLVSPEPPPKGFLVMGSKFRYSGRTQAQTRQASALIDRPAPFFERSSSKRYTM
SRSLDGAEFSRPASVSENHDAGPDGDKRDEDGESGGQRSEAEEGEVRTPTKIKELKFLDKPEDVLLKHQASINELKRTLKEPNSKLIHRD

--------------------------------------------------------------

>26823_26823_38_EPB41L1-ROMO1_EPB41L1_chr20_34785963_ENST00000373950_ROMO1_chr20_34287555_ENST00000374077_length(amino acids)=556AA_BP=477
MRADGTGSSKADPDTEARPVQQGPHTLSLDMEEKDYSEADGLSERTTPSKAQKSPQKIAKKYKSAICRVTLLDASEYECEVENWLDPSKE
IKKQIRSSPWNFAFTVKFYPPDPAQLTEDITRYYLCLQLRADIITGRLPCSFVTHALLGSYAVQAELGDYDAEEHVGNYVSELRFAPNQT
RELEERIMELHKTYRGMTPGEAEIHFLENAKKLSMYGVDLHHAKDSEGIDIMLGVCANGLLIYRDRLRINRFAWPKILKISYKRSNFYIK
IRPGEYEQFESTIGFKLPNHRSAKRLWKVCIEHHTFFRLVSPEPPPKGFLVMGSKFRYSGRTQAQTRQASALIDRPAPFFERSSSKRYTM
SRSLDGAEFSRPASVSENHDAGPDGDKRDEDGESGGQRSEAEEGEVRTPTKIKELKFLDKPEDVLLKHQASINELKRTLKEPNSKLIHRD
RDWERERRLPSSPASPSPKGTPEKANEMPVAVGPYGQSQPSCFDRVKMGFVMGCAVGMAAGALFGTFSCLRIGMRGRELMGGIGKTMMQS

--------------------------------------------------------------

>26823_26823_39_EPB41L1-ROMO1_EPB41L1_chr20_34785963_ENST00000373950_ROMO1_chr20_34287555_ENST00000374078_length(amino acids)=556AA_BP=477
MRADGTGSSKADPDTEARPVQQGPHTLSLDMEEKDYSEADGLSERTTPSKAQKSPQKIAKKYKSAICRVTLLDASEYECEVENWLDPSKE
IKKQIRSSPWNFAFTVKFYPPDPAQLTEDITRYYLCLQLRADIITGRLPCSFVTHALLGSYAVQAELGDYDAEEHVGNYVSELRFAPNQT
RELEERIMELHKTYRGMTPGEAEIHFLENAKKLSMYGVDLHHAKDSEGIDIMLGVCANGLLIYRDRLRINRFAWPKILKISYKRSNFYIK
IRPGEYEQFESTIGFKLPNHRSAKRLWKVCIEHHTFFRLVSPEPPPKGFLVMGSKFRYSGRTQAQTRQASALIDRPAPFFERSSSKRYTM
SRSLDGAEFSRPASVSENHDAGPDGDKRDEDGESGGQRSEAEEGEVRTPTKIKELKFLDKPEDVLLKHQASINELKRTLKEPNSKLIHRD
RDWERERRLPSSPASPSPKGTPEKANEMPVAVGPYGQSQPSCFDRVKMGFVMGCAVGMAAGALFGTFSCLRIGMRGRELMGGIGKTMMQS

--------------------------------------------------------------

>26823_26823_40_EPB41L1-ROMO1_EPB41L1_chr20_34785963_ENST00000373950_ROMO1_chr20_34287555_ENST00000397416_length(amino acids)=556AA_BP=477
MRADGTGSSKADPDTEARPVQQGPHTLSLDMEEKDYSEADGLSERTTPSKAQKSPQKIAKKYKSAICRVTLLDASEYECEVENWLDPSKE
IKKQIRSSPWNFAFTVKFYPPDPAQLTEDITRYYLCLQLRADIITGRLPCSFVTHALLGSYAVQAELGDYDAEEHVGNYVSELRFAPNQT
RELEERIMELHKTYRGMTPGEAEIHFLENAKKLSMYGVDLHHAKDSEGIDIMLGVCANGLLIYRDRLRINRFAWPKILKISYKRSNFYIK
IRPGEYEQFESTIGFKLPNHRSAKRLWKVCIEHHTFFRLVSPEPPPKGFLVMGSKFRYSGRTQAQTRQASALIDRPAPFFERSSSKRYTM
SRSLDGAEFSRPASVSENHDAGPDGDKRDEDGESGGQRSEAEEGEVRTPTKIKELKFLDKPEDVLLKHQASINELKRTLKEPNSKLIHRD
RDWERERRLPSSPASPSPKGTPEKANEMPVAVGPYGQSQPSCFDRVKMGFVMGCAVGMAAGALFGTFSCLRIGMRGRELMGGIGKTMMQS

--------------------------------------------------------------

>26823_26823_41_EPB41L1-ROMO1_EPB41L1_chr20_34785963_ENST00000441639_ROMO1_chr20_34287554_ENST00000374072_length(amino acids)=561AA_BP=502
MTDRSSCPRGAGVDRGGSLDMEEKDYSEADGLSERTTPSKAQKSPQKIAKKYKSAICRVTLLDASEYECEVEKHGRGQVLFDLVCEHLNL
LEKDYFGLTFCDADSQKNWLDPSKEIKKQIRSSPWNFAFTVKFYPPDPAQLTEDITRYYLCLQLRADIITGRLPCSFVTHALLGSYAVQA
ELGDYDAEEHVGNYVSELRFAPNQTRELEERIMELHKTYRGMTPGEAEIHFLENAKKLSMYGVDLHHAKDSEGIDIMLGVCANGLLIYRD
RLRINRFAWPKILKISYKRSNFYIKIRPGEYEQFESTIGFKLPNHRSAKRLWKVCIEHHTFFRLVSPEPPPKGFLVMGSKFRYSGRTQAQ
TRQASALIDRPAPFFERSSSKRYTMSRSLDGAEFSRPASVSENHDAGPDGDKRDEDGESGGQRSEAEEGEVRTPTKIKELKFLDKPEDVL
LKHQASINELKRTLKEPNSKLIHRDRDWERERRLPSSPASPSPKGTPEKANEMPVAVGPYGQSQPSCFDRVKMGFVMGCAVGMAAGALFG

--------------------------------------------------------------

>26823_26823_42_EPB41L1-ROMO1_EPB41L1_chr20_34785963_ENST00000441639_ROMO1_chr20_34287554_ENST00000374077_length(amino acids)=581AA_BP=502
MTDRSSCPRGAGVDRGGSLDMEEKDYSEADGLSERTTPSKAQKSPQKIAKKYKSAICRVTLLDASEYECEVEKHGRGQVLFDLVCEHLNL
LEKDYFGLTFCDADSQKNWLDPSKEIKKQIRSSPWNFAFTVKFYPPDPAQLTEDITRYYLCLQLRADIITGRLPCSFVTHALLGSYAVQA
ELGDYDAEEHVGNYVSELRFAPNQTRELEERIMELHKTYRGMTPGEAEIHFLENAKKLSMYGVDLHHAKDSEGIDIMLGVCANGLLIYRD
RLRINRFAWPKILKISYKRSNFYIKIRPGEYEQFESTIGFKLPNHRSAKRLWKVCIEHHTFFRLVSPEPPPKGFLVMGSKFRYSGRTQAQ
TRQASALIDRPAPFFERSSSKRYTMSRSLDGAEFSRPASVSENHDAGPDGDKRDEDGESGGQRSEAEEGEVRTPTKIKELKFLDKPEDVL
LKHQASINELKRTLKEPNSKLIHRDRDWERERRLPSSPASPSPKGTPEKANEMPVAVGPYGQSQPSCFDRVKMGFVMGCAVGMAAGALFG

--------------------------------------------------------------

>26823_26823_43_EPB41L1-ROMO1_EPB41L1_chr20_34785963_ENST00000441639_ROMO1_chr20_34287554_ENST00000374078_length(amino acids)=581AA_BP=502
MTDRSSCPRGAGVDRGGSLDMEEKDYSEADGLSERTTPSKAQKSPQKIAKKYKSAICRVTLLDASEYECEVEKHGRGQVLFDLVCEHLNL
LEKDYFGLTFCDADSQKNWLDPSKEIKKQIRSSPWNFAFTVKFYPPDPAQLTEDITRYYLCLQLRADIITGRLPCSFVTHALLGSYAVQA
ELGDYDAEEHVGNYVSELRFAPNQTRELEERIMELHKTYRGMTPGEAEIHFLENAKKLSMYGVDLHHAKDSEGIDIMLGVCANGLLIYRD
RLRINRFAWPKILKISYKRSNFYIKIRPGEYEQFESTIGFKLPNHRSAKRLWKVCIEHHTFFRLVSPEPPPKGFLVMGSKFRYSGRTQAQ
TRQASALIDRPAPFFERSSSKRYTMSRSLDGAEFSRPASVSENHDAGPDGDKRDEDGESGGQRSEAEEGEVRTPTKIKELKFLDKPEDVL
LKHQASINELKRTLKEPNSKLIHRDRDWERERRLPSSPASPSPKGTPEKANEMPVAVGPYGQSQPSCFDRVKMGFVMGCAVGMAAGALFG

--------------------------------------------------------------

>26823_26823_44_EPB41L1-ROMO1_EPB41L1_chr20_34785963_ENST00000441639_ROMO1_chr20_34287554_ENST00000397416_length(amino acids)=581AA_BP=502
MTDRSSCPRGAGVDRGGSLDMEEKDYSEADGLSERTTPSKAQKSPQKIAKKYKSAICRVTLLDASEYECEVEKHGRGQVLFDLVCEHLNL
LEKDYFGLTFCDADSQKNWLDPSKEIKKQIRSSPWNFAFTVKFYPPDPAQLTEDITRYYLCLQLRADIITGRLPCSFVTHALLGSYAVQA
ELGDYDAEEHVGNYVSELRFAPNQTRELEERIMELHKTYRGMTPGEAEIHFLENAKKLSMYGVDLHHAKDSEGIDIMLGVCANGLLIYRD
RLRINRFAWPKILKISYKRSNFYIKIRPGEYEQFESTIGFKLPNHRSAKRLWKVCIEHHTFFRLVSPEPPPKGFLVMGSKFRYSGRTQAQ
TRQASALIDRPAPFFERSSSKRYTMSRSLDGAEFSRPASVSENHDAGPDGDKRDEDGESGGQRSEAEEGEVRTPTKIKELKFLDKPEDVL
LKHQASINELKRTLKEPNSKLIHRDRDWERERRLPSSPASPSPKGTPEKANEMPVAVGPYGQSQPSCFDRVKMGFVMGCAVGMAAGALFG

--------------------------------------------------------------

>26823_26823_45_EPB41L1-ROMO1_EPB41L1_chr20_34785963_ENST00000441639_ROMO1_chr20_34287555_ENST00000374072_length(amino acids)=561AA_BP=502
MTDRSSCPRGAGVDRGGSLDMEEKDYSEADGLSERTTPSKAQKSPQKIAKKYKSAICRVTLLDASEYECEVEKHGRGQVLFDLVCEHLNL
LEKDYFGLTFCDADSQKNWLDPSKEIKKQIRSSPWNFAFTVKFYPPDPAQLTEDITRYYLCLQLRADIITGRLPCSFVTHALLGSYAVQA
ELGDYDAEEHVGNYVSELRFAPNQTRELEERIMELHKTYRGMTPGEAEIHFLENAKKLSMYGVDLHHAKDSEGIDIMLGVCANGLLIYRD
RLRINRFAWPKILKISYKRSNFYIKIRPGEYEQFESTIGFKLPNHRSAKRLWKVCIEHHTFFRLVSPEPPPKGFLVMGSKFRYSGRTQAQ
TRQASALIDRPAPFFERSSSKRYTMSRSLDGAEFSRPASVSENHDAGPDGDKRDEDGESGGQRSEAEEGEVRTPTKIKELKFLDKPEDVL
LKHQASINELKRTLKEPNSKLIHRDRDWERERRLPSSPASPSPKGTPEKANEMPVAVGPYGQSQPSCFDRVKMGFVMGCAVGMAAGALFG

--------------------------------------------------------------

>26823_26823_46_EPB41L1-ROMO1_EPB41L1_chr20_34785963_ENST00000441639_ROMO1_chr20_34287555_ENST00000374077_length(amino acids)=581AA_BP=502
MTDRSSCPRGAGVDRGGSLDMEEKDYSEADGLSERTTPSKAQKSPQKIAKKYKSAICRVTLLDASEYECEVEKHGRGQVLFDLVCEHLNL
LEKDYFGLTFCDADSQKNWLDPSKEIKKQIRSSPWNFAFTVKFYPPDPAQLTEDITRYYLCLQLRADIITGRLPCSFVTHALLGSYAVQA
ELGDYDAEEHVGNYVSELRFAPNQTRELEERIMELHKTYRGMTPGEAEIHFLENAKKLSMYGVDLHHAKDSEGIDIMLGVCANGLLIYRD
RLRINRFAWPKILKISYKRSNFYIKIRPGEYEQFESTIGFKLPNHRSAKRLWKVCIEHHTFFRLVSPEPPPKGFLVMGSKFRYSGRTQAQ
TRQASALIDRPAPFFERSSSKRYTMSRSLDGAEFSRPASVSENHDAGPDGDKRDEDGESGGQRSEAEEGEVRTPTKIKELKFLDKPEDVL
LKHQASINELKRTLKEPNSKLIHRDRDWERERRLPSSPASPSPKGTPEKANEMPVAVGPYGQSQPSCFDRVKMGFVMGCAVGMAAGALFG

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>26823_26823_47_EPB41L1-ROMO1_EPB41L1_chr20_34785963_ENST00000441639_ROMO1_chr20_34287555_ENST00000374078_length(amino acids)=581AA_BP=502
MTDRSSCPRGAGVDRGGSLDMEEKDYSEADGLSERTTPSKAQKSPQKIAKKYKSAICRVTLLDASEYECEVEKHGRGQVLFDLVCEHLNL
LEKDYFGLTFCDADSQKNWLDPSKEIKKQIRSSPWNFAFTVKFYPPDPAQLTEDITRYYLCLQLRADIITGRLPCSFVTHALLGSYAVQA
ELGDYDAEEHVGNYVSELRFAPNQTRELEERIMELHKTYRGMTPGEAEIHFLENAKKLSMYGVDLHHAKDSEGIDIMLGVCANGLLIYRD
RLRINRFAWPKILKISYKRSNFYIKIRPGEYEQFESTIGFKLPNHRSAKRLWKVCIEHHTFFRLVSPEPPPKGFLVMGSKFRYSGRTQAQ
TRQASALIDRPAPFFERSSSKRYTMSRSLDGAEFSRPASVSENHDAGPDGDKRDEDGESGGQRSEAEEGEVRTPTKIKELKFLDKPEDVL
LKHQASINELKRTLKEPNSKLIHRDRDWERERRLPSSPASPSPKGTPEKANEMPVAVGPYGQSQPSCFDRVKMGFVMGCAVGMAAGALFG

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>26823_26823_48_EPB41L1-ROMO1_EPB41L1_chr20_34785963_ENST00000441639_ROMO1_chr20_34287555_ENST00000397416_length(amino acids)=581AA_BP=502
MTDRSSCPRGAGVDRGGSLDMEEKDYSEADGLSERTTPSKAQKSPQKIAKKYKSAICRVTLLDASEYECEVEKHGRGQVLFDLVCEHLNL
LEKDYFGLTFCDADSQKNWLDPSKEIKKQIRSSPWNFAFTVKFYPPDPAQLTEDITRYYLCLQLRADIITGRLPCSFVTHALLGSYAVQA
ELGDYDAEEHVGNYVSELRFAPNQTRELEERIMELHKTYRGMTPGEAEIHFLENAKKLSMYGVDLHHAKDSEGIDIMLGVCANGLLIYRD
RLRINRFAWPKILKISYKRSNFYIKIRPGEYEQFESTIGFKLPNHRSAKRLWKVCIEHHTFFRLVSPEPPPKGFLVMGSKFRYSGRTQAQ
TRQASALIDRPAPFFERSSSKRYTMSRSLDGAEFSRPASVSENHDAGPDGDKRDEDGESGGQRSEAEEGEVRTPTKIKELKFLDKPEDVL
LKHQASINELKRTLKEPNSKLIHRDRDWERERRLPSSPASPSPKGTPEKANEMPVAVGPYGQSQPSCFDRVKMGFVMGCAVGMAAGALFG

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Fusion Protein Functional Features


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr20:34785963/chr20:34287554)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
EPB41L1

Q9H4G0

.
FUNCTION: May function to confer stability and plasticity to neuronal membrane via multiple interactions, including the spectrin-actin-based cytoskeleton, integral membrane channels and membrane-associated guanylate kinases.FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

* Minus value of BPloci means that the break pointn is located before the CDS.
- Retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneEPB41L1chr20:34785963chr20:34287554ENST00000202028+132097_378482.0780.0DomainFERM
HgeneEPB41L1chr20:34785963chr20:34287554ENST00000338074+142297_378556.0882.0DomainFERM
HgeneEPB41L1chr20:34785963chr20:34287554ENST00000373941+132197_378556.0881.0DomainFERM
HgeneEPB41L1chr20:34785963chr20:34287554ENST00000373946+121997_378513.0702.0DomainFERM
HgeneEPB41L1chr20:34785963chr20:34287554ENST00000373950+132197_378447.0773.0DomainFERM
HgeneEPB41L1chr20:34785963chr20:34287554ENST00000441639+121997_378482.0780.0DomainFERM
HgeneEPB41L1chr20:34785963chr20:34287555ENST00000202028+132097_378482.0780.0DomainFERM
HgeneEPB41L1chr20:34785963chr20:34287555ENST00000338074+142297_378556.0882.0DomainFERM
HgeneEPB41L1chr20:34785963chr20:34287555ENST00000373941+132197_378556.0881.0DomainFERM
HgeneEPB41L1chr20:34785963chr20:34287555ENST00000373946+121997_378513.0702.0DomainFERM
HgeneEPB41L1chr20:34785963chr20:34287555ENST00000373950+132197_378447.0773.0DomainFERM
HgeneEPB41L1chr20:34785963chr20:34287555ENST00000441639+121997_378482.0780.0DomainFERM
HgeneEPB41L1chr20:34785963chr20:34287554ENST00000338074+1422483_541556.0882.0RegionNote=Spectrin--actin-binding
HgeneEPB41L1chr20:34785963chr20:34287554ENST00000373941+1321483_541556.0881.0RegionNote=Spectrin--actin-binding
HgeneEPB41L1chr20:34785963chr20:34287555ENST00000338074+1422483_541556.0882.0RegionNote=Spectrin--actin-binding
HgeneEPB41L1chr20:34785963chr20:34287555ENST00000373941+1321483_541556.0881.0RegionNote=Spectrin--actin-binding
TgeneROMO1chr20:34785963chr20:34287554ENST000003366950242_60080.0RegionNote=Sufficient for antibacterial activity
TgeneROMO1chr20:34785963chr20:34287554ENST000003740720342_600.060.0RegionNote=Sufficient for antibacterial activity
TgeneROMO1chr20:34785963chr20:34287554ENST000003740770342_600.080.0RegionNote=Sufficient for antibacterial activity
TgeneROMO1chr20:34785963chr20:34287554ENST000003740780342_600.080.0RegionNote=Sufficient for antibacterial activity
TgeneROMO1chr20:34785963chr20:34287554ENST000003974160342_600.080.0RegionNote=Sufficient for antibacterial activity
TgeneROMO1chr20:34785963chr20:34287555ENST000003366950242_60080.0RegionNote=Sufficient for antibacterial activity
TgeneROMO1chr20:34785963chr20:34287555ENST000003740720342_600.060.0RegionNote=Sufficient for antibacterial activity
TgeneROMO1chr20:34785963chr20:34287555ENST000003740770342_600.080.0RegionNote=Sufficient for antibacterial activity
TgeneROMO1chr20:34785963chr20:34287555ENST000003740780342_600.080.0RegionNote=Sufficient for antibacterial activity
TgeneROMO1chr20:34785963chr20:34287555ENST000003974160342_600.080.0RegionNote=Sufficient for antibacterial activity
TgeneROMO1chr20:34785963chr20:34287554ENST000003366950222_44080.0TransmembraneHelical
TgeneROMO1chr20:34785963chr20:34287554ENST000003740720322_440.060.0TransmembraneHelical
TgeneROMO1chr20:34785963chr20:34287554ENST000003740770322_440.080.0TransmembraneHelical
TgeneROMO1chr20:34785963chr20:34287554ENST000003740780322_440.080.0TransmembraneHelical
TgeneROMO1chr20:34785963chr20:34287554ENST000003974160322_440.080.0TransmembraneHelical
TgeneROMO1chr20:34785963chr20:34287555ENST000003366950222_44080.0TransmembraneHelical
TgeneROMO1chr20:34785963chr20:34287555ENST000003740720322_440.060.0TransmembraneHelical
TgeneROMO1chr20:34785963chr20:34287555ENST000003740770322_440.080.0TransmembraneHelical
TgeneROMO1chr20:34785963chr20:34287555ENST000003740780322_440.080.0TransmembraneHelical
TgeneROMO1chr20:34785963chr20:34287555ENST000003974160322_440.080.0TransmembraneHelical

- Not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneEPB41L1chr20:34785963chr20:34287554ENST00000202028+1320483_541482.0780.0RegionNote=Spectrin--actin-binding
HgeneEPB41L1chr20:34785963chr20:34287554ENST00000202028+1320746_881482.0780.0RegionNote=C-terminal (CTD)
HgeneEPB41L1chr20:34785963chr20:34287554ENST00000338074+1422746_881556.0882.0RegionNote=C-terminal (CTD)
HgeneEPB41L1chr20:34785963chr20:34287554ENST00000373941+1321746_881556.0881.0RegionNote=C-terminal (CTD)
HgeneEPB41L1chr20:34785963chr20:34287554ENST00000373946+1219483_541513.0702.0RegionNote=Spectrin--actin-binding
HgeneEPB41L1chr20:34785963chr20:34287554ENST00000373946+1219746_881513.0702.0RegionNote=C-terminal (CTD)
HgeneEPB41L1chr20:34785963chr20:34287554ENST00000373950+1321483_541447.0773.0RegionNote=Spectrin--actin-binding
HgeneEPB41L1chr20:34785963chr20:34287554ENST00000373950+1321746_881447.0773.0RegionNote=C-terminal (CTD)
HgeneEPB41L1chr20:34785963chr20:34287554ENST00000441639+1219483_541482.0780.0RegionNote=Spectrin--actin-binding
HgeneEPB41L1chr20:34785963chr20:34287554ENST00000441639+1219746_881482.0780.0RegionNote=C-terminal (CTD)
HgeneEPB41L1chr20:34785963chr20:34287555ENST00000202028+1320483_541482.0780.0RegionNote=Spectrin--actin-binding
HgeneEPB41L1chr20:34785963chr20:34287555ENST00000202028+1320746_881482.0780.0RegionNote=C-terminal (CTD)
HgeneEPB41L1chr20:34785963chr20:34287555ENST00000338074+1422746_881556.0882.0RegionNote=C-terminal (CTD)
HgeneEPB41L1chr20:34785963chr20:34287555ENST00000373941+1321746_881556.0881.0RegionNote=C-terminal (CTD)
HgeneEPB41L1chr20:34785963chr20:34287555ENST00000373946+1219483_541513.0702.0RegionNote=Spectrin--actin-binding
HgeneEPB41L1chr20:34785963chr20:34287555ENST00000373946+1219746_881513.0702.0RegionNote=C-terminal (CTD)
HgeneEPB41L1chr20:34785963chr20:34287555ENST00000373950+1321483_541447.0773.0RegionNote=Spectrin--actin-binding
HgeneEPB41L1chr20:34785963chr20:34287555ENST00000373950+1321746_881447.0773.0RegionNote=C-terminal (CTD)
HgeneEPB41L1chr20:34785963chr20:34287555ENST00000441639+1219483_541482.0780.0RegionNote=Spectrin--actin-binding
HgeneEPB41L1chr20:34785963chr20:34287555ENST00000441639+1219746_881482.0780.0RegionNote=C-terminal (CTD)


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Fusion Protein Structures

check button PDB and CIF files of the predicted fusion proteins
* Here we show the 3D structure of the fusion proteins using Mol*. AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Model confidence is shown from the pLDDT values per residue. pLDDT corresponds to the model’s prediction of its score on the local Distance Difference Test. It is a measure of local accuracy (from AlphfaFold website). To color code individual residues, we transformed individual PDB files into CIF format.
Fusion protein PDB link (fusion AA seq ID in FusionPDB)HgeneHchrHbpHstrandTgeneTchrTbpTstrandAA seqLen(AA seq)


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pLDDT score distribution

check button pLDDT score distribution of the predicted wild-type structures of two partner proteins from AlphaFold2
* AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100.
EPB41L1_pLDDT.png
all structure
all structure
ROMO1_pLDDT.png
all structure
all structure

check button pLDDT score distribution of the predicted fusion protein structures from AlphaFold2
* AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100.


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Ramachandran Plot of Fusion Protein Structure


check button Ramachandran plot of the torsional angles - phi (φ)and psi (ψ) - of the residues (amino acids) contained in this fusion protein peptide.
Fusion AA seq ID in FusionPDB and their Ramachandran plots

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Fusion Protein-Protein Interaction


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type from validated records (BIOGRID-3.4.160)
GenePPI interactors


check button Protein-protein interactors based on sequence similarity (STRING)
GeneSTRING network
EPB41L1
ROMO1


check button - Retained interactions in fusion protein (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost interactions due to fusion (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs to EPB41L1-ROMO1


check button Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDrugSourcePMID

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Related Diseases to EPB41L1-ROMO1


check button Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDiseaseSourcePMID

check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource