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Center for Computational Systems Medicine level1
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Fusion Gene Summary

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Fusion Gene Sample Information

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Fusion ORF Analysis

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Fusion Amino Acid Sequences

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Fusion Protein Functional Features

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Fusion Protein-Protein Interaction

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Related drugs with this fusion protein

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Related disease with this fusion protein

Fusion Protein:AHI1-MYB

Fusion Protein Summary

check button Fusion gene summary
Fusion partner gene informationFusion gene name: AHI1-MYB
FusionPDB ID: 3095
FusionGDB2.0 ID: 3095
HgeneTgene
Gene symbol

AHI1

MYB

Gene ID

54806

4602

Gene nameAbelson helper integration site 1MYB proto-oncogene, transcription factor
SynonymsAHI-1|JBTS3|ORF1|dJ71N10.1Cmyb|c-myb|c-myb_CDS|efg
Cytomap

6q23.3

6q23.3

Type of geneprotein-codingprotein-coding
Descriptionjouberinabelson helper integration site 1 protein homologcontatins SH3 and WD40 domainstranscriptional activator Myboncogene AMVproto-oncogene c-Mybv-myb avian myeloblastosis viral oncogene homolog
Modification date2020031320200313
UniProtAcc

Q8N157

A2RUH7

Ensembl transtripts involved in fusion geneENST idsENST00000367800, ENST00000417892, 
ENST00000457866, ENST00000327035, 
ENST00000367798, ENST00000488690, 
ENST00000528103, ENST00000531527, 
ENST00000534469, 		ENST00000531845, 
ENST00000420123, ENST00000527615, 
ENST00000316528, ENST00000442647, 
ENST00000525369, ENST00000528774, 
ENST00000533624, ENST00000534044, 
ENST00000534121, ENST00000341911, 
ENST00000367814, 
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)* DoF score10 X 11 X 6=6607 X 7 X 4=196
# samples 108
** MAII scorelog2(10/660*10)=-2.72246602447109
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(8/196*10)=-1.29278174922785
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context (manual curation of fusion genes in FusionPDB)

PubMed: AHI1 [Title/Abstract] AND MYB [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)AHI1(135679270)-MYB(135539002), # samples:2
Anticipated loss of major functional domain due to fusion event.AHI1-MYB seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
AHI1-MYB seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
AHI1-MYB seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
AHI1-MYB seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
AHI1-MYB seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
AHI1-MYB seems lost the major protein functional domain in Tgene partner, which is a CGC due to the frame-shifted ORF.
AHI1-MYB seems lost the major protein functional domain in Tgene partner, which is a transcription factor due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneMYB

GO:0045944

positive regulation of transcription by RNA polymerase II

10233885|20484083


check buttonFusion gene breakpoints across AHI1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across MYB (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure


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Fusion Gene Sample Information

check buttonFusion gene information from FusionGDB2.0.
check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-A2-A3XS-01AAHI1chr6

135679270

-MYBchr6

135539002

+


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Fusion ORF Analysis


check buttonFusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000367800AHI1chr6135679270-ENST00000341911MYBchr6135539002+4686338221734981093
ENST00000367800AHI1chr6135679270-ENST00000367814MYBchr6135539002+4692338221734981093
ENST00000457866AHI1chr6135679270-ENST00000316528MYBchr6135539002+4772346429935801093
ENST00000457866AHI1chr6135679270-ENST00000442647MYBchr6135539002+4772346429935801093
ENST00000457866AHI1chr6135679270-ENST00000534121MYBchr6135539002+3581346429935801094
ENST00000457866AHI1chr6135679270-ENST00000533624MYBchr6135539002+3581346429935801094
ENST00000457866AHI1chr6135679270-ENST00000534044MYBchr6135539002+3581346429935801094
ENST00000457866AHI1chr6135679270-ENST00000528774MYBchr6135539002+3581346429935801094
ENST00000417892AHI1chr6135679270-ENST00000341911MYBchr6135539002+266113571301473447
ENST00000417892AHI1chr6135679270-ENST00000367814MYBchr6135539002+266713571301473447

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000367800ENST00000341911AHI1chr6135679270-MYBchr6135539002+0.0001257320.99987423
ENST00000367800ENST00000367814AHI1chr6135679270-MYBchr6135539002+0.0001225670.99987745
ENST00000457866ENST00000316528AHI1chr6135679270-MYBchr6135539002+0.0001286450.9998714
ENST00000457866ENST00000442647AHI1chr6135679270-MYBchr6135539002+0.0001286450.9998714
ENST00000457866ENST00000534121AHI1chr6135679270-MYBchr6135539002+0.0002215960.99977845
ENST00000457866ENST00000533624AHI1chr6135679270-MYBchr6135539002+0.0002215960.99977845
ENST00000457866ENST00000534044AHI1chr6135679270-MYBchr6135539002+0.0002215960.99977845
ENST00000457866ENST00000528774AHI1chr6135679270-MYBchr6135539002+0.0002215960.99977845
ENST00000417892ENST00000341911AHI1chr6135679270-MYBchr6135539002+0.0001965130.9998035
ENST00000417892ENST00000367814AHI1chr6135679270-MYBchr6135539002+0.0001899150.99981016

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Fusion Amino Acid Sequences


check button For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

>3095_3095_1_AHI1-MYB_AHI1_chr6_135679270_ENST00000367800_MYB_chr6_135539002_ENST00000341911_length(amino acids)=1093AA_BP=1055
MPTAESEAKVKTKVRFEELLKTHSDLMREKKKLKKKLVRSEENISPDTIRSNLHYMKETTSDDPDTIRSNLPHIKETTSDDVSAANTNNL
KKSTRVTKNKLRNTQLATENPNGDASVEEDKQGKPNKKVIKTVPQLTTQDLKPETPENKVDSTHQKTHTKPQPGVDHQKSEKANEGREET
DLEEDEELMQAYQCHVTEEMAKEIKRKIRKKLKEQLTYFPSDTLFHDDKLSSEKRKKKKEVPVFSKAETSTLTISGDTVEGEQKKESSVR
SVSSDSHQDDEISSMEQSTEDSMQDDTKPKPKKTKKKTKAVADNNEDVDGDGVHEITSRDSPVYPKCLLDDDLVLGVYIHRTDRLKSDFM
ISHPMVKIHVVDEHTGQYVKKDDSGRPVSSYYEKENVDYILPIMTQPYDFKQLKSRLPEWEEQIVFNENFPYLLRGSDESPKVILFFEIL
DFLSVDEIKNNSEVQNQECGFRKIAWAFLKLLGANGNANINSKLRLQLYYPPTKPRSPLSVVEAFEWWSKCPRNHYPSTLYVTVRGLKVP
DCIKPSYRSMMALQEEKGKPVHCERHHESSSVDTEPGLEESKEVIKWKRLPGQACRIPNKHLFSLNAGERGCFCLDFSHNGRILAAACAS
RDGYPIILYEIPSGRFMRELCGHLNIIYDLSWSKDDHYILTSSSDGTARIWKNEINNTNTFRVLPHPSFVYTAKFHPAVRELVVTGCYDS
MIRIWKVEMREDSAILVRQFDVHKSFINSLCFDTEGHHMYSGDCTGVIVVWNTYVKINDLEHSVHHWTINKEIKETEFKGIPISYLEIHP
NGKRLLIHTKDSTLRIMDLRILVARKFVGAANYREKIHSTLTPCGTFLFAGSEDGIVYVWNPETGEQVAMYSDLPFKSPIRDISYHPFEN
MVAFCAFGQNEPILLYIYDFHVAQQEAEMFKRYNGTFPLPGIHQSQDALCTCPKLPHQGSFQIDEFVHTESSSTKMQLVKQRLETVTEVI
RSCAAKVNKNLSFTSPPAVSSQQSKLKQSNMLTAQEILHQFGFTQTGIISIERKPCNHQVDTAPTPCSSTWEPASCGKMEEQMTSSSQAR

--------------------------------------------------------------

>3095_3095_2_AHI1-MYB_AHI1_chr6_135679270_ENST00000367800_MYB_chr6_135539002_ENST00000367814_length(amino acids)=1093AA_BP=1055
MPTAESEAKVKTKVRFEELLKTHSDLMREKKKLKKKLVRSEENISPDTIRSNLHYMKETTSDDPDTIRSNLPHIKETTSDDVSAANTNNL
KKSTRVTKNKLRNTQLATENPNGDASVEEDKQGKPNKKVIKTVPQLTTQDLKPETPENKVDSTHQKTHTKPQPGVDHQKSEKANEGREET
DLEEDEELMQAYQCHVTEEMAKEIKRKIRKKLKEQLTYFPSDTLFHDDKLSSEKRKKKKEVPVFSKAETSTLTISGDTVEGEQKKESSVR
SVSSDSHQDDEISSMEQSTEDSMQDDTKPKPKKTKKKTKAVADNNEDVDGDGVHEITSRDSPVYPKCLLDDDLVLGVYIHRTDRLKSDFM
ISHPMVKIHVVDEHTGQYVKKDDSGRPVSSYYEKENVDYILPIMTQPYDFKQLKSRLPEWEEQIVFNENFPYLLRGSDESPKVILFFEIL
DFLSVDEIKNNSEVQNQECGFRKIAWAFLKLLGANGNANINSKLRLQLYYPPTKPRSPLSVVEAFEWWSKCPRNHYPSTLYVTVRGLKVP
DCIKPSYRSMMALQEEKGKPVHCERHHESSSVDTEPGLEESKEVIKWKRLPGQACRIPNKHLFSLNAGERGCFCLDFSHNGRILAAACAS
RDGYPIILYEIPSGRFMRELCGHLNIIYDLSWSKDDHYILTSSSDGTARIWKNEINNTNTFRVLPHPSFVYTAKFHPAVRELVVTGCYDS
MIRIWKVEMREDSAILVRQFDVHKSFINSLCFDTEGHHMYSGDCTGVIVVWNTYVKINDLEHSVHHWTINKEIKETEFKGIPISYLEIHP
NGKRLLIHTKDSTLRIMDLRILVARKFVGAANYREKIHSTLTPCGTFLFAGSEDGIVYVWNPETGEQVAMYSDLPFKSPIRDISYHPFEN
MVAFCAFGQNEPILLYIYDFHVAQQEAEMFKRYNGTFPLPGIHQSQDALCTCPKLPHQGSFQIDEFVHTESSSTKMQLVKQRLETVTEVI
RSCAAKVNKNLSFTSPPAVSSQQSKLKQSNMLTAQEILHQFGFTQTGIISIERKPCNHQVDTAPTPCSSTWEPASCGKMEEQMTSSSQAR

--------------------------------------------------------------

>3095_3095_3_AHI1-MYB_AHI1_chr6_135679270_ENST00000417892_MYB_chr6_135539002_ENST00000341911_length(amino acids)=447AA_BP=409
MRELCGHLNIIYDLSWSKDDHYILTSSSDGTARIWKNEINNTNTFRVLPHPSFVYTAKFHPAVRELVVTGCYDSMIRIWKVEMREDSAIL
VRQFDVHKSFINSLCFDTEGHHMYSGDCTGVIVVWNTYVKINDLEHSVHHWTINKEIKETEFKGIPISYLEIHPNGKRLLIHTKDSTLRI
MDLRILVARKFVGAANYREKIHSTLTPCGTFLFAGSEDGIVYVWNPETGEQVAMYSDLPFKSPIRDISYHPFENMVAFCAFGQNEPILLY
IYDFHVAQQEAEMFKRYNGTFPLPGIHQSQDALCTCPKLPHQGSFQIDEFVHTESSSTKMQLVKQRLETVTEVIRSCAAKVNKNLSFTSP

--------------------------------------------------------------

>3095_3095_4_AHI1-MYB_AHI1_chr6_135679270_ENST00000417892_MYB_chr6_135539002_ENST00000367814_length(amino acids)=447AA_BP=409
MRELCGHLNIIYDLSWSKDDHYILTSSSDGTARIWKNEINNTNTFRVLPHPSFVYTAKFHPAVRELVVTGCYDSMIRIWKVEMREDSAIL
VRQFDVHKSFINSLCFDTEGHHMYSGDCTGVIVVWNTYVKINDLEHSVHHWTINKEIKETEFKGIPISYLEIHPNGKRLLIHTKDSTLRI
MDLRILVARKFVGAANYREKIHSTLTPCGTFLFAGSEDGIVYVWNPETGEQVAMYSDLPFKSPIRDISYHPFENMVAFCAFGQNEPILLY
IYDFHVAQQEAEMFKRYNGTFPLPGIHQSQDALCTCPKLPHQGSFQIDEFVHTESSSTKMQLVKQRLETVTEVIRSCAAKVNKNLSFTSP

--------------------------------------------------------------

>3095_3095_5_AHI1-MYB_AHI1_chr6_135679270_ENST00000457866_MYB_chr6_135539002_ENST00000316528_length(amino acids)=1093AA_BP=1055
MPTAESEAKVKTKVRFEELLKTHSDLMREKKKLKKKLVRSEENISPDTIRSNLHYMKETTSDDPDTIRSNLPHIKETTSDDVSAANTNNL
KKSTRVTKNKLRNTQLATENPNGDASVEEDKQGKPNKKVIKTVPQLTTQDLKPETPENKVDSTHQKTHTKPQPGVDHQKSEKANEGREET
DLEEDEELMQAYQCHVTEEMAKEIKRKIRKKLKEQLTYFPSDTLFHDDKLSSEKRKKKKEVPVFSKAETSTLTISGDTVEGEQKKESSVR
SVSSDSHQDDEISSMEQSTEDSMQDDTKPKPKKTKKKTKAVADNNEDVDGDGVHEITSRDSPVYPKCLLDDDLVLGVYIHRTDRLKSDFM
ISHPMVKIHVVDEHTGQYVKKDDSGRPVSSYYEKENVDYILPIMTQPYDFKQLKSRLPEWEEQIVFNENFPYLLRGSDESPKVILFFEIL
DFLSVDEIKNNSEVQNQECGFRKIAWAFLKLLGANGNANINSKLRLQLYYPPTKPRSPLSVVEAFEWWSKCPRNHYPSTLYVTVRGLKVP
DCIKPSYRSMMALQEEKGKPVHCERHHESSSVDTEPGLEESKEVIKWKRLPGQACRIPNKHLFSLNAGERGCFCLDFSHNGRILAAACAS
RDGYPIILYEIPSGRFMRELCGHLNIIYDLSWSKDDHYILTSSSDGTARIWKNEINNTNTFRVLPHPSFVYTAKFHPAVRELVVTGCYDS
MIRIWKVEMREDSAILVRQFDVHKSFINSLCFDTEGHHMYSGDCTGVIVVWNTYVKINDLEHSVHHWTINKEIKETEFKGIPISYLEIHP
NGKRLLIHTKDSTLRIMDLRILVARKFVGAANYREKIHSTLTPCGTFLFAGSEDGIVYVWNPETGEQVAMYSDLPFKSPIRDISYHPFEN
MVAFCAFGQNEPILLYIYDFHVAQQEAEMFKRYNGTFPLPGIHQSQDALCTCPKLPHQGSFQIDEFVHTESSSTKMQLVKQRLETVTEVI
RSCAAKVNKNLSFTSPPAVSSQQSKLKQSNMLTAQEILHQFGFTQTGIISIERKPCNHQVDTAPTPCSSTWEPASCGKMEEQMTSSSQAR

--------------------------------------------------------------

>3095_3095_6_AHI1-MYB_AHI1_chr6_135679270_ENST00000457866_MYB_chr6_135539002_ENST00000442647_length(amino acids)=1093AA_BP=1055
MPTAESEAKVKTKVRFEELLKTHSDLMREKKKLKKKLVRSEENISPDTIRSNLHYMKETTSDDPDTIRSNLPHIKETTSDDVSAANTNNL
KKSTRVTKNKLRNTQLATENPNGDASVEEDKQGKPNKKVIKTVPQLTTQDLKPETPENKVDSTHQKTHTKPQPGVDHQKSEKANEGREET
DLEEDEELMQAYQCHVTEEMAKEIKRKIRKKLKEQLTYFPSDTLFHDDKLSSEKRKKKKEVPVFSKAETSTLTISGDTVEGEQKKESSVR
SVSSDSHQDDEISSMEQSTEDSMQDDTKPKPKKTKKKTKAVADNNEDVDGDGVHEITSRDSPVYPKCLLDDDLVLGVYIHRTDRLKSDFM
ISHPMVKIHVVDEHTGQYVKKDDSGRPVSSYYEKENVDYILPIMTQPYDFKQLKSRLPEWEEQIVFNENFPYLLRGSDESPKVILFFEIL
DFLSVDEIKNNSEVQNQECGFRKIAWAFLKLLGANGNANINSKLRLQLYYPPTKPRSPLSVVEAFEWWSKCPRNHYPSTLYVTVRGLKVP
DCIKPSYRSMMALQEEKGKPVHCERHHESSSVDTEPGLEESKEVIKWKRLPGQACRIPNKHLFSLNAGERGCFCLDFSHNGRILAAACAS
RDGYPIILYEIPSGRFMRELCGHLNIIYDLSWSKDDHYILTSSSDGTARIWKNEINNTNTFRVLPHPSFVYTAKFHPAVRELVVTGCYDS
MIRIWKVEMREDSAILVRQFDVHKSFINSLCFDTEGHHMYSGDCTGVIVVWNTYVKINDLEHSVHHWTINKEIKETEFKGIPISYLEIHP
NGKRLLIHTKDSTLRIMDLRILVARKFVGAANYREKIHSTLTPCGTFLFAGSEDGIVYVWNPETGEQVAMYSDLPFKSPIRDISYHPFEN
MVAFCAFGQNEPILLYIYDFHVAQQEAEMFKRYNGTFPLPGIHQSQDALCTCPKLPHQGSFQIDEFVHTESSSTKMQLVKQRLETVTEVI
RSCAAKVNKNLSFTSPPAVSSQQSKLKQSNMLTAQEILHQFGFTQTGIISIERKPCNHQVDTAPTPCSSTWEPASCGKMEEQMTSSSQAR

--------------------------------------------------------------

>3095_3095_7_AHI1-MYB_AHI1_chr6_135679270_ENST00000457866_MYB_chr6_135539002_ENST00000528774_length(amino acids)=1094AA_BP=1055
MPTAESEAKVKTKVRFEELLKTHSDLMREKKKLKKKLVRSEENISPDTIRSNLHYMKETTSDDPDTIRSNLPHIKETTSDDVSAANTNNL
KKSTRVTKNKLRNTQLATENPNGDASVEEDKQGKPNKKVIKTVPQLTTQDLKPETPENKVDSTHQKTHTKPQPGVDHQKSEKANEGREET
DLEEDEELMQAYQCHVTEEMAKEIKRKIRKKLKEQLTYFPSDTLFHDDKLSSEKRKKKKEVPVFSKAETSTLTISGDTVEGEQKKESSVR
SVSSDSHQDDEISSMEQSTEDSMQDDTKPKPKKTKKKTKAVADNNEDVDGDGVHEITSRDSPVYPKCLLDDDLVLGVYIHRTDRLKSDFM
ISHPMVKIHVVDEHTGQYVKKDDSGRPVSSYYEKENVDYILPIMTQPYDFKQLKSRLPEWEEQIVFNENFPYLLRGSDESPKVILFFEIL
DFLSVDEIKNNSEVQNQECGFRKIAWAFLKLLGANGNANINSKLRLQLYYPPTKPRSPLSVVEAFEWWSKCPRNHYPSTLYVTVRGLKVP
DCIKPSYRSMMALQEEKGKPVHCERHHESSSVDTEPGLEESKEVIKWKRLPGQACRIPNKHLFSLNAGERGCFCLDFSHNGRILAAACAS
RDGYPIILYEIPSGRFMRELCGHLNIIYDLSWSKDDHYILTSSSDGTARIWKNEINNTNTFRVLPHPSFVYTAKFHPAVRELVVTGCYDS
MIRIWKVEMREDSAILVRQFDVHKSFINSLCFDTEGHHMYSGDCTGVIVVWNTYVKINDLEHSVHHWTINKEIKETEFKGIPISYLEIHP
NGKRLLIHTKDSTLRIMDLRILVARKFVGAANYREKIHSTLTPCGTFLFAGSEDGIVYVWNPETGEQVAMYSDLPFKSPIRDISYHPFEN
MVAFCAFGQNEPILLYIYDFHVAQQEAEMFKRYNGTFPLPGIHQSQDALCTCPKLPHQGSFQIDEFVHTESSSTKMQLVKQRLETVTEVI
RSCAAKVNKNLSFTSPPAVSSQQSKLKQSNMLTAQEILHQFGFTQTGIISIERKPCNHQVDTAPTPCSSTWEPASCGKMEEQMTSSSQAR

--------------------------------------------------------------

>3095_3095_8_AHI1-MYB_AHI1_chr6_135679270_ENST00000457866_MYB_chr6_135539002_ENST00000533624_length(amino acids)=1094AA_BP=1055
MPTAESEAKVKTKVRFEELLKTHSDLMREKKKLKKKLVRSEENISPDTIRSNLHYMKETTSDDPDTIRSNLPHIKETTSDDVSAANTNNL
KKSTRVTKNKLRNTQLATENPNGDASVEEDKQGKPNKKVIKTVPQLTTQDLKPETPENKVDSTHQKTHTKPQPGVDHQKSEKANEGREET
DLEEDEELMQAYQCHVTEEMAKEIKRKIRKKLKEQLTYFPSDTLFHDDKLSSEKRKKKKEVPVFSKAETSTLTISGDTVEGEQKKESSVR
SVSSDSHQDDEISSMEQSTEDSMQDDTKPKPKKTKKKTKAVADNNEDVDGDGVHEITSRDSPVYPKCLLDDDLVLGVYIHRTDRLKSDFM
ISHPMVKIHVVDEHTGQYVKKDDSGRPVSSYYEKENVDYILPIMTQPYDFKQLKSRLPEWEEQIVFNENFPYLLRGSDESPKVILFFEIL
DFLSVDEIKNNSEVQNQECGFRKIAWAFLKLLGANGNANINSKLRLQLYYPPTKPRSPLSVVEAFEWWSKCPRNHYPSTLYVTVRGLKVP
DCIKPSYRSMMALQEEKGKPVHCERHHESSSVDTEPGLEESKEVIKWKRLPGQACRIPNKHLFSLNAGERGCFCLDFSHNGRILAAACAS
RDGYPIILYEIPSGRFMRELCGHLNIIYDLSWSKDDHYILTSSSDGTARIWKNEINNTNTFRVLPHPSFVYTAKFHPAVRELVVTGCYDS
MIRIWKVEMREDSAILVRQFDVHKSFINSLCFDTEGHHMYSGDCTGVIVVWNTYVKINDLEHSVHHWTINKEIKETEFKGIPISYLEIHP
NGKRLLIHTKDSTLRIMDLRILVARKFVGAANYREKIHSTLTPCGTFLFAGSEDGIVYVWNPETGEQVAMYSDLPFKSPIRDISYHPFEN
MVAFCAFGQNEPILLYIYDFHVAQQEAEMFKRYNGTFPLPGIHQSQDALCTCPKLPHQGSFQIDEFVHTESSSTKMQLVKQRLETVTEVI
RSCAAKVNKNLSFTSPPAVSSQQSKLKQSNMLTAQEILHQFGFTQTGIISIERKPCNHQVDTAPTPCSSTWEPASCGKMEEQMTSSSQAR

--------------------------------------------------------------

>3095_3095_9_AHI1-MYB_AHI1_chr6_135679270_ENST00000457866_MYB_chr6_135539002_ENST00000534044_length(amino acids)=1094AA_BP=1055
MPTAESEAKVKTKVRFEELLKTHSDLMREKKKLKKKLVRSEENISPDTIRSNLHYMKETTSDDPDTIRSNLPHIKETTSDDVSAANTNNL
KKSTRVTKNKLRNTQLATENPNGDASVEEDKQGKPNKKVIKTVPQLTTQDLKPETPENKVDSTHQKTHTKPQPGVDHQKSEKANEGREET
DLEEDEELMQAYQCHVTEEMAKEIKRKIRKKLKEQLTYFPSDTLFHDDKLSSEKRKKKKEVPVFSKAETSTLTISGDTVEGEQKKESSVR
SVSSDSHQDDEISSMEQSTEDSMQDDTKPKPKKTKKKTKAVADNNEDVDGDGVHEITSRDSPVYPKCLLDDDLVLGVYIHRTDRLKSDFM
ISHPMVKIHVVDEHTGQYVKKDDSGRPVSSYYEKENVDYILPIMTQPYDFKQLKSRLPEWEEQIVFNENFPYLLRGSDESPKVILFFEIL
DFLSVDEIKNNSEVQNQECGFRKIAWAFLKLLGANGNANINSKLRLQLYYPPTKPRSPLSVVEAFEWWSKCPRNHYPSTLYVTVRGLKVP
DCIKPSYRSMMALQEEKGKPVHCERHHESSSVDTEPGLEESKEVIKWKRLPGQACRIPNKHLFSLNAGERGCFCLDFSHNGRILAAACAS
RDGYPIILYEIPSGRFMRELCGHLNIIYDLSWSKDDHYILTSSSDGTARIWKNEINNTNTFRVLPHPSFVYTAKFHPAVRELVVTGCYDS
MIRIWKVEMREDSAILVRQFDVHKSFINSLCFDTEGHHMYSGDCTGVIVVWNTYVKINDLEHSVHHWTINKEIKETEFKGIPISYLEIHP
NGKRLLIHTKDSTLRIMDLRILVARKFVGAANYREKIHSTLTPCGTFLFAGSEDGIVYVWNPETGEQVAMYSDLPFKSPIRDISYHPFEN
MVAFCAFGQNEPILLYIYDFHVAQQEAEMFKRYNGTFPLPGIHQSQDALCTCPKLPHQGSFQIDEFVHTESSSTKMQLVKQRLETVTEVI
RSCAAKVNKNLSFTSPPAVSSQQSKLKQSNMLTAQEILHQFGFTQTGIISIERKPCNHQVDTAPTPCSSTWEPASCGKMEEQMTSSSQAR

--------------------------------------------------------------

>3095_3095_10_AHI1-MYB_AHI1_chr6_135679270_ENST00000457866_MYB_chr6_135539002_ENST00000534121_length(amino acids)=1094AA_BP=1055
MPTAESEAKVKTKVRFEELLKTHSDLMREKKKLKKKLVRSEENISPDTIRSNLHYMKETTSDDPDTIRSNLPHIKETTSDDVSAANTNNL
KKSTRVTKNKLRNTQLATENPNGDASVEEDKQGKPNKKVIKTVPQLTTQDLKPETPENKVDSTHQKTHTKPQPGVDHQKSEKANEGREET
DLEEDEELMQAYQCHVTEEMAKEIKRKIRKKLKEQLTYFPSDTLFHDDKLSSEKRKKKKEVPVFSKAETSTLTISGDTVEGEQKKESSVR
SVSSDSHQDDEISSMEQSTEDSMQDDTKPKPKKTKKKTKAVADNNEDVDGDGVHEITSRDSPVYPKCLLDDDLVLGVYIHRTDRLKSDFM
ISHPMVKIHVVDEHTGQYVKKDDSGRPVSSYYEKENVDYILPIMTQPYDFKQLKSRLPEWEEQIVFNENFPYLLRGSDESPKVILFFEIL
DFLSVDEIKNNSEVQNQECGFRKIAWAFLKLLGANGNANINSKLRLQLYYPPTKPRSPLSVVEAFEWWSKCPRNHYPSTLYVTVRGLKVP
DCIKPSYRSMMALQEEKGKPVHCERHHESSSVDTEPGLEESKEVIKWKRLPGQACRIPNKHLFSLNAGERGCFCLDFSHNGRILAAACAS
RDGYPIILYEIPSGRFMRELCGHLNIIYDLSWSKDDHYILTSSSDGTARIWKNEINNTNTFRVLPHPSFVYTAKFHPAVRELVVTGCYDS
MIRIWKVEMREDSAILVRQFDVHKSFINSLCFDTEGHHMYSGDCTGVIVVWNTYVKINDLEHSVHHWTINKEIKETEFKGIPISYLEIHP
NGKRLLIHTKDSTLRIMDLRILVARKFVGAANYREKIHSTLTPCGTFLFAGSEDGIVYVWNPETGEQVAMYSDLPFKSPIRDISYHPFEN
MVAFCAFGQNEPILLYIYDFHVAQQEAEMFKRYNGTFPLPGIHQSQDALCTCPKLPHQGSFQIDEFVHTESSSTKMQLVKQRLETVTEVI
RSCAAKVNKNLSFTSPPAVSSQQSKLKQSNMLTAQEILHQFGFTQTGIISIERKPCNHQVDTAPTPCSSTWEPASCGKMEEQMTSSSQAR

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Fusion Protein Functional Features


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr6:135679270/chr6:135539002)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
AHI1

Q8N157

MYB

A2RUH7

FUNCTION: Involved in vesicle trafficking and required for ciliogenesis, formation of primary non-motile cilium, and recruitment of RAB8A to the basal body of primary cilium. Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Involved in neuronal differentiation. As a positive modulator of classical Wnt signaling, may play a crucial role in ciliary signaling during cerebellum embryonic development (PubMed:21623382). {ECO:0000250|UniProtKB:Q8K3E5, ECO:0000269|PubMed:21623382}.FUNCTION: Myosin-binding protein which plays a role in cardiac function (PubMed:28778945). Seems to regulate conduction in the atria and ventricular conduction systems (PubMed:28778945). {ECO:0000269|PubMed:28778945}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

* Minus value of BPloci means that the break pointn is located before the CDS.
- Retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneAHI1chr6:135679270chr6:135539002ENST00000367800-222713_451055.01197.0Coiled coilOntology_term=ECO:0000255
HgeneAHI1chr6:135679270chr6:135539002ENST00000457866-232813_451055.01197.0Coiled coilOntology_term=ECO:0000255
HgeneAHI1chr6:135679270chr6:135539002ENST00000367800-2227234_2391055.01197.0Compositional biasNote=Poly-Lys
HgeneAHI1chr6:135679270chr6:135539002ENST00000457866-2328234_2391055.01197.0Compositional biasNote=Poly-Lys
HgeneAHI1chr6:135679270chr6:135539002ENST00000367800-2227607_6491055.01197.0RepeatNote=WD 1
HgeneAHI1chr6:135679270chr6:135539002ENST00000367800-2227652_6911055.01197.0RepeatNote=WD 2
HgeneAHI1chr6:135679270chr6:135539002ENST00000367800-2227695_7351055.01197.0RepeatNote=WD 3
HgeneAHI1chr6:135679270chr6:135539002ENST00000367800-2227742_7811055.01197.0RepeatNote=WD 4
HgeneAHI1chr6:135679270chr6:135539002ENST00000367800-2227797_8371055.01197.0RepeatNote=WD 5
HgeneAHI1chr6:135679270chr6:135539002ENST00000367800-2227841_8801055.01197.0RepeatNote=WD 6
HgeneAHI1chr6:135679270chr6:135539002ENST00000367800-2227885_9261055.01197.0RepeatNote=WD 7
HgeneAHI1chr6:135679270chr6:135539002ENST00000457866-2328607_6491055.01197.0RepeatNote=WD 1
HgeneAHI1chr6:135679270chr6:135539002ENST00000457866-2328652_6911055.01197.0RepeatNote=WD 2
HgeneAHI1chr6:135679270chr6:135539002ENST00000457866-2328695_7351055.01197.0RepeatNote=WD 3
HgeneAHI1chr6:135679270chr6:135539002ENST00000457866-2328742_7811055.01197.0RepeatNote=WD 4
HgeneAHI1chr6:135679270chr6:135539002ENST00000457866-2328797_8371055.01197.0RepeatNote=WD 5
HgeneAHI1chr6:135679270chr6:135539002ENST00000457866-2328841_8801055.01197.0RepeatNote=WD 6
HgeneAHI1chr6:135679270chr6:135539002ENST00000457866-2328885_9261055.01197.0RepeatNote=WD 7

- Not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneAHI1chr6:135679270chr6:135539002ENST00000327035-12313_4501054.0Coiled coilOntology_term=ECO:0000255
HgeneAHI1chr6:135679270chr6:135539002ENST00000327035-123234_23901054.0Compositional biasNote=Poly-Lys
HgeneAHI1chr6:135679270chr6:135539002ENST00000327035-1231051_111101054.0DomainSH3
HgeneAHI1chr6:135679270chr6:135539002ENST00000367800-22271051_11111055.01197.0DomainSH3
HgeneAHI1chr6:135679270chr6:135539002ENST00000457866-23281051_11111055.01197.0DomainSH3
HgeneAHI1chr6:135679270chr6:135539002ENST00000327035-123607_64901054.0RepeatNote=WD 1
HgeneAHI1chr6:135679270chr6:135539002ENST00000327035-123652_69101054.0RepeatNote=WD 2
HgeneAHI1chr6:135679270chr6:135539002ENST00000327035-123695_73501054.0RepeatNote=WD 3
HgeneAHI1chr6:135679270chr6:135539002ENST00000327035-123742_78101054.0RepeatNote=WD 4
HgeneAHI1chr6:135679270chr6:135539002ENST00000327035-123797_83701054.0RepeatNote=WD 5
HgeneAHI1chr6:135679270chr6:135539002ENST00000327035-123841_88001054.0RepeatNote=WD 6
HgeneAHI1chr6:135679270chr6:135539002ENST00000327035-123885_92601054.0RepeatNote=WD 7
TgeneMYBchr6:135679270chr6:135539002ENST000003419111416115_138723.0762.0DNA bindingH-T-H motif
TgeneMYBchr6:135679270chr6:135539002ENST000003419111416166_189723.0762.0DNA bindingH-T-H motif
TgeneMYBchr6:135679270chr6:135539002ENST00000341911141663_86723.0762.0DNA bindingH-T-H motif
TgeneMYBchr6:135679270chr6:135539002ENST000003678141315115_138602.0641.0DNA bindingH-T-H motif
TgeneMYBchr6:135679270chr6:135539002ENST000003678141315166_189602.0641.0DNA bindingH-T-H motif
TgeneMYBchr6:135679270chr6:135539002ENST00000367814131563_86602.0641.0DNA bindingH-T-H motif
TgeneMYBchr6:135679270chr6:135539002ENST000004426471315115_138599.0638.0DNA bindingH-T-H motif
TgeneMYBchr6:135679270chr6:135539002ENST000004426471315166_189599.0638.0DNA bindingH-T-H motif
TgeneMYBchr6:135679270chr6:135539002ENST00000442647131563_86599.0638.0DNA bindingH-T-H motif
TgeneMYBchr6:135679270chr6:135539002ENST000005253691214115_138517.0556.0DNA bindingH-T-H motif
TgeneMYBchr6:135679270chr6:135539002ENST000005253691214166_189517.0556.0DNA bindingH-T-H motif
TgeneMYBchr6:135679270chr6:135539002ENST00000525369121463_86517.0556.0DNA bindingH-T-H motif
TgeneMYBchr6:135679270chr6:135539002ENST000005287741416115_138720.0759.0DNA bindingH-T-H motif
TgeneMYBchr6:135679270chr6:135539002ENST000005287741416166_189720.0759.0DNA bindingH-T-H motif
TgeneMYBchr6:135679270chr6:135539002ENST00000528774141663_86720.0759.0DNA bindingH-T-H motif
TgeneMYBchr6:135679270chr6:135539002ENST000005336241214115_138567.0606.0DNA bindingH-T-H motif
TgeneMYBchr6:135679270chr6:135539002ENST000005336241214166_189567.0606.0DNA bindingH-T-H motif
TgeneMYBchr6:135679270chr6:135539002ENST00000533624121463_86567.0606.0DNA bindingH-T-H motif
TgeneMYBchr6:135679270chr6:135539002ENST000005340441214115_138565.0604.0DNA bindingH-T-H motif
TgeneMYBchr6:135679270chr6:135539002ENST000005340441214166_189565.0604.0DNA bindingH-T-H motif
TgeneMYBchr6:135679270chr6:135539002ENST00000534044121463_86565.0604.0DNA bindingH-T-H motif
TgeneMYBchr6:135679270chr6:135539002ENST000005341211416115_138707.0746.0DNA bindingH-T-H motif
TgeneMYBchr6:135679270chr6:135539002ENST000005341211416166_189707.0746.0DNA bindingH-T-H motif
TgeneMYBchr6:135679270chr6:135539002ENST00000534121141663_86707.0746.0DNA bindingH-T-H motif
TgeneMYBchr6:135679270chr6:135539002ENST000003419111416143_193723.0762.0DomainHTH myb-type 3
TgeneMYBchr6:135679270chr6:135539002ENST00000341911141635_86723.0762.0DomainHTH myb-type 1
TgeneMYBchr6:135679270chr6:135539002ENST00000341911141687_142723.0762.0DomainHTH myb-type 2
TgeneMYBchr6:135679270chr6:135539002ENST000003678141315143_193602.0641.0DomainHTH myb-type 3
TgeneMYBchr6:135679270chr6:135539002ENST00000367814131535_86602.0641.0DomainHTH myb-type 1
TgeneMYBchr6:135679270chr6:135539002ENST00000367814131587_142602.0641.0DomainHTH myb-type 2
TgeneMYBchr6:135679270chr6:135539002ENST000004426471315143_193599.0638.0DomainHTH myb-type 3
TgeneMYBchr6:135679270chr6:135539002ENST00000442647131535_86599.0638.0DomainHTH myb-type 1
TgeneMYBchr6:135679270chr6:135539002ENST00000442647131587_142599.0638.0DomainHTH myb-type 2
TgeneMYBchr6:135679270chr6:135539002ENST000005253691214143_193517.0556.0DomainHTH myb-type 3
TgeneMYBchr6:135679270chr6:135539002ENST00000525369121435_86517.0556.0DomainHTH myb-type 1
TgeneMYBchr6:135679270chr6:135539002ENST00000525369121487_142517.0556.0DomainHTH myb-type 2
TgeneMYBchr6:135679270chr6:135539002ENST000005287741416143_193720.0759.0DomainHTH myb-type 3
TgeneMYBchr6:135679270chr6:135539002ENST00000528774141635_86720.0759.0DomainHTH myb-type 1
TgeneMYBchr6:135679270chr6:135539002ENST00000528774141687_142720.0759.0DomainHTH myb-type 2
TgeneMYBchr6:135679270chr6:135539002ENST000005336241214143_193567.0606.0DomainHTH myb-type 3
TgeneMYBchr6:135679270chr6:135539002ENST00000533624121435_86567.0606.0DomainHTH myb-type 1
TgeneMYBchr6:135679270chr6:135539002ENST00000533624121487_142567.0606.0DomainHTH myb-type 2
TgeneMYBchr6:135679270chr6:135539002ENST000005340441214143_193565.0604.0DomainHTH myb-type 3
TgeneMYBchr6:135679270chr6:135539002ENST00000534044121435_86565.0604.0DomainHTH myb-type 1
TgeneMYBchr6:135679270chr6:135539002ENST00000534044121487_142565.0604.0DomainHTH myb-type 2
TgeneMYBchr6:135679270chr6:135539002ENST000005341211416143_193707.0746.0DomainHTH myb-type 3
TgeneMYBchr6:135679270chr6:135539002ENST00000534121141635_86707.0746.0DomainHTH myb-type 1
TgeneMYBchr6:135679270chr6:135539002ENST00000534121141687_142707.0746.0DomainHTH myb-type 2
TgeneMYBchr6:135679270chr6:135539002ENST000003419111416275_327723.0762.0RegionTranscription activation domain (PubMed:2189102)
TgeneMYBchr6:135679270chr6:135539002ENST000003419111416328_465723.0762.0RegionNegative regulatory domain
TgeneMYBchr6:135679270chr6:135539002ENST000003419111416376_397723.0762.0RegionNote=Leucine-zipper
TgeneMYBchr6:135679270chr6:135539002ENST000003678141315275_327602.0641.0RegionTranscription activation domain (PubMed:2189102)
TgeneMYBchr6:135679270chr6:135539002ENST000003678141315328_465602.0641.0RegionNegative regulatory domain
TgeneMYBchr6:135679270chr6:135539002ENST000003678141315376_397602.0641.0RegionNote=Leucine-zipper
TgeneMYBchr6:135679270chr6:135539002ENST000004426471315275_327599.0638.0RegionTranscription activation domain (PubMed:2189102)
TgeneMYBchr6:135679270chr6:135539002ENST000004426471315328_465599.0638.0RegionNegative regulatory domain
TgeneMYBchr6:135679270chr6:135539002ENST000004426471315376_397599.0638.0RegionNote=Leucine-zipper
TgeneMYBchr6:135679270chr6:135539002ENST000005253691214275_327517.0556.0RegionTranscription activation domain (PubMed:2189102)
TgeneMYBchr6:135679270chr6:135539002ENST000005253691214328_465517.0556.0RegionNegative regulatory domain
TgeneMYBchr6:135679270chr6:135539002ENST000005253691214376_397517.0556.0RegionNote=Leucine-zipper
TgeneMYBchr6:135679270chr6:135539002ENST000005287741416275_327720.0759.0RegionTranscription activation domain (PubMed:2189102)
TgeneMYBchr6:135679270chr6:135539002ENST000005287741416328_465720.0759.0RegionNegative regulatory domain
TgeneMYBchr6:135679270chr6:135539002ENST000005287741416376_397720.0759.0RegionNote=Leucine-zipper
TgeneMYBchr6:135679270chr6:135539002ENST000005336241214275_327567.0606.0RegionTranscription activation domain (PubMed:2189102)
TgeneMYBchr6:135679270chr6:135539002ENST000005336241214328_465567.0606.0RegionNegative regulatory domain
TgeneMYBchr6:135679270chr6:135539002ENST000005336241214376_397567.0606.0RegionNote=Leucine-zipper
TgeneMYBchr6:135679270chr6:135539002ENST000005340441214275_327565.0604.0RegionTranscription activation domain (PubMed:2189102)
TgeneMYBchr6:135679270chr6:135539002ENST000005340441214328_465565.0604.0RegionNegative regulatory domain
TgeneMYBchr6:135679270chr6:135539002ENST000005340441214376_397565.0604.0RegionNote=Leucine-zipper
TgeneMYBchr6:135679270chr6:135539002ENST000005341211416275_327707.0746.0RegionTranscription activation domain (PubMed:2189102)
TgeneMYBchr6:135679270chr6:135539002ENST000005341211416328_465707.0746.0RegionNegative regulatory domain
TgeneMYBchr6:135679270chr6:135539002ENST000005341211416376_397707.0746.0RegionNote=Leucine-zipper


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Fusion Protein-Protein Interaction


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type from validated records (BIOGRID-3.4.160)
GenePPI interactors
MYBPML, SMARCA2, CREBBP, NCL, CEBPB, CEBPE, MAF, SND1, PAX5, FBXW7, ZMYND11, KMT2A, WDR5, RBBP5, ASH2L, MEN1, NLK, HIPK2, HLF, SP100, PARP1, EP300, TRIM28, SKI, SIN3A, NCOR1, UBE2I, CHD3, KAT2B, RPL4, LEF1, Fbxw7, KAT5, GATA3, STAT5A, TRAF6, FBXW5, DDB1, CUL4A, PIAS1, RBX1, SUMO1, SUMO2, CCND3, MYOZ2, PPM1K, ERC2, UPF2, KAT2A, HSPA8, HIST3H3, HIST1H2AB, HIST1H2BB, HIST1H3A, HIST1H4A, KIAA1429, DCAF15, APEX1, PAIP1, UPF1, BMI1, DDX39A, SETD1A, LIN9, KMT2D, E2F6, HIVEP1, YY1, CTCF, ZNF131, BLM, ZBTB33, PHF6, PCGF6, EHMT1, TRPS1, KMT2B, ZNF148, ZEB2, ZEB1, CUX1, ARID3A, ZNF536, RAD21, WIZ, NR2C1, RPL34, ATXN1, MLLT6, RPL37A, NFIA, RLF, TAF9, GPATCH4, BEND3, ZMYM4, NIPBL, ZNF66, PAXIP1, KANSL1, POGZ, C11orf30, ARID3B, MGA, ZNF709, KDM2B, GATAD1, BAP1, L3MBTL2, ZBTB9, ZBTB10, EHMT2, CIC, ZNF644, CXXC1, CHD7, KANSL3, DACH1, PHF8, SATB2, SMC3, ZNF281, NOP16,


check button Protein-protein interactors based on sequence similarity (STRING)
GeneSTRING network
AHI1
MYBall structure


check button - Retained interactions in fusion protein (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost interactions due to fusion (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneAHI1chr6:135679270chr6:135539002ENST00000327035-123141_43401054.0HAP1
TgeneMYBchr6:135679270chr6:135539002ENST00000341911141690_193723.0762.0HIPK2 and NLK
TgeneMYBchr6:135679270chr6:135539002ENST00000367814131590_193602.0641.0HIPK2 and NLK
TgeneMYBchr6:135679270chr6:135539002ENST00000442647131590_193599.0638.0HIPK2 and NLK
TgeneMYBchr6:135679270chr6:135539002ENST00000525369121490_193517.0556.0HIPK2 and NLK
TgeneMYBchr6:135679270chr6:135539002ENST00000528774141690_193720.0759.0HIPK2 and NLK
TgeneMYBchr6:135679270chr6:135539002ENST00000533624121490_193567.0606.0HIPK2 and NLK
TgeneMYBchr6:135679270chr6:135539002ENST00000534044121490_193565.0604.0HIPK2 and NLK
TgeneMYBchr6:135679270chr6:135539002ENST00000534121141690_193707.0746.0HIPK2 and NLK


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Related Drugs to AHI1-MYB


check button Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDrugSourcePMID

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Related Diseases to AHI1-MYB


check button Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDiseaseSourcePMID

check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneMYBC0010606Adenoid Cystic Carcinoma2CTD_human
TgeneMYBC0017638Glioma2CTD_human
TgeneMYBC0259783mixed gliomas2CTD_human
TgeneMYBC0555198Malignant Glioma2CTD_human
TgeneMYBC1961099Precursor T-Cell Lymphoblastic Leukemia-Lymphoma2CTD_human;ORPHANET
TgeneMYBC0004096Asthma1CTD_human
TgeneMYBC0023437Acute Basophilic Leukemia1ORPHANET
TgeneMYBC2363903Angiocentric glioma1ORPHANET