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	Fusion Gene Summary
	Fusion Gene Sample Information
	Fusion ORF Analysis
	Fusion Amino Acid Sequences
	Fusion Protein Functional Features
	Fusion Protein Structure
	pLDDT scores
	Ramachandran Plot of Fusion Protein Structure
	Fusion Protein-Protein Interaction
	Related drugs with this fusion protein
	Related disease with this fusion protein

Fusion Protein:GGA2-PRKCB

Fusion Protein Summary

Fusion gene summary

Fusion partner gene information	Fusion gene name: GGA2-PRKCB
	FusionPDB ID: 33002
	FusionGDB2.0 ID: 33002
		Hgene	Tgene
	Gene symbol	GGA2	PRKCB
	Gene ID	23062	5579
	Gene name	golgi associated, gamma adaptin ear containing, ARF binding protein 2	protein kinase C beta
	Synonyms	VEAR	PKC-beta\|PKCB\|PKCI(2)\|PKCbeta\|PRKCB1\|PRKCB2
	Cytomap	16p12.2	16p12.2-p12.1
	Type of gene	protein-coding	protein-coding
	Description	ADP-ribosylation factor-binding protein GGA2VHS domain and ear domain of gamma-adaptinVHS domain and ear domain-containing proteingamma-adaptin-related protein 2golgi-localized, gamma ear-containing, ARF-binding protein 2	protein kinase C beta typePKC-Bprotein kinase C, beta 1 polypeptide
	Modification date	20200313	20200313
	UniProtAcc	Q9UJY4	.
Ensembl transtripts involved in fusion gene	ENST ids	ENST00000309859, ENST00000567468, ENST00000569182,	ENST00000482000, ENST00000498058, ENST00000303531, ENST00000321728,
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)	* DoF score	7 X 7 X 4=196	20 X 15 X 13=3900
	# samples	8	25
	** MAII score	log2(8/196*10)=-1.29278174922785 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(25/3900*10)=-3.96347412397489 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context (manual curation of fusion genes in FusionPDB)	PubMed: GGA2 [Title/Abstract] AND PRKCB [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)	GGA2(23502998)-PRKCB(23999829), # samples:3
Anticipated loss of major functional domain due to fusion event.	GGA2-PRKCB seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. GGA2-PRKCB seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. GGA2-PRKCB seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. GGA2-PRKCB seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Hgene	GGA2	GO:0034394	protein localization to cell surface	27901063
Hgene	GGA2	GO:0043001	Golgi to plasma membrane protein transport	27901063
Tgene	PRKCB	GO:0010827	regulation of glucose transmembrane transport	25982116
Tgene	PRKCB	GO:0035408	histone H3-T6 phosphorylation	20228790

Fusion gene breakpoints across GGA2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across PRKCB (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

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Fusion Gene Sample Information

Fusion gene information from FusionGDB2.0.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	LAML	TCGA-AB-2929-03A	GGA2	chr16	23478534	-	PRKCB	chr16	24230943	+
ChimerDB4	LGG	TCGA-HT-A5RC-01A	GGA2	chr16	23502998	-	PRKCB	chr16	23999829	+
ChimerDB4	LGG	TCGA-HT-A5RC	GGA2	chr16	23502998	-	PRKCB	chr16	23999829	+

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Fusion ORF Analysis

Fusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000309859	GGA2	chr16	23502998	-	ENST00000321728	PRKCB	chr16	23999829	+	2867	558	83	2368	761
ENST00000309859	GGA2	chr16	23502998	-	ENST00000303531	PRKCB	chr16	23999829	+	8170	558	83	2374	763
ENST00000567468	GGA2	chr16	23502998	-	ENST00000321728	PRKCB	chr16	23999829	+	2797	488	13	2298	761
ENST00000567468	GGA2	chr16	23502998	-	ENST00000303531	PRKCB	chr16	23999829	+	8100	488	13	2304	763

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000309859	ENST00000321728	GGA2	chr16	23502998	-	PRKCB	chr16	23999829	+	0.001479827	0.9985202
ENST00000309859	ENST00000303531	GGA2	chr16	23502998	-	PRKCB	chr16	23999829	+	0.000626314	0.99937373
ENST00000567468	ENST00000321728	GGA2	chr16	23502998	-	PRKCB	chr16	23999829	+	0.001297496	0.9987025
ENST00000567468	ENST00000303531	GGA2	chr16	23502998	-	PRKCB	chr16	23999829	+	0.000594999	0.999405

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Fusion Amino Acid Sequences

For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

>33002_33002_1_GGA2-PRKCB_GGA2_chr16_23502998_ENST00000309859_PRKCB_chr16_23999829_ENST00000303531_length(amino acids)=763AA_BP=158
MAATAVAAAVAGTESAQGPPGPAASLELWLNKATDPSMSEQDWSAIQNFCEQVNTDPNGPTHAPWLLAHKIQSPQEKEALYALTVLEMCM
NHCGEKFHSEVAKFRFLNELIKVLSPKYLGSWATGKVKGRVIEILFSWTVWFPEDIKIRDAYQMLKKQVCCFVVHKRCHEFVTFSCPGAD
KGPASDDPRSKHKFKIHTYSSPTFCDHCGSLLYGLIHQGMKCDTCMMNVHKRCVMNVPSLCGTDHTERRGRIYIQAHIDRDVLIVLVRDA
KNLVPMDPNGLSDPYVKLKLIPDPKSESKQKTKTIKCSLNPEWNETFRFQLKESDKDRRLSVEIWDWDLTSRNDFMGSLSFGISELQKAS
VDGWFKLLSQEEGEYFNVPVPPEGSEANEELRQKFERAKISQGTKVPEEKTTNTVSKFDNNGNRDRMKLTDFNFLMVLGKGSFGKVMLSE
RKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPGKPPFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEI
AIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAP
FEGEDEDELFQSIMEHNVAYPKSMSKEAVAICKGLMTKHPGKRLGCGPEGERDIKEHAFFRYIDWEKLERKEIQPPYKPKACGRNAENFD

--------------------------------------------------------------

>33002_33002_2_GGA2-PRKCB_GGA2_chr16_23502998_ENST00000309859_PRKCB_chr16_23999829_ENST00000321728_length(amino acids)=761AA_BP=158
MAATAVAAAVAGTESAQGPPGPAASLELWLNKATDPSMSEQDWSAIQNFCEQVNTDPNGPTHAPWLLAHKIQSPQEKEALYALTVLEMCM
NHCGEKFHSEVAKFRFLNELIKVLSPKYLGSWATGKVKGRVIEILFSWTVWFPEDIKIRDAYQMLKKQVCCFVVHKRCHEFVTFSCPGAD
KGPASDDPRSKHKFKIHTYSSPTFCDHCGSLLYGLIHQGMKCDTCMMNVHKRCVMNVPSLCGTDHTERRGRIYIQAHIDRDVLIVLVRDA
KNLVPMDPNGLSDPYVKLKLIPDPKSESKQKTKTIKCSLNPEWNETFRFQLKESDKDRRLSVEIWDWDLTSRNDFMGSLSFGISELQKAS
VDGWFKLLSQEEGEYFNVPVPPEGSEANEELRQKFERAKISQGTKVPEEKTTNTVSKFDNNGNRDRMKLTDFNFLMVLGKGSFGKVMLSE
RKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPGKPPFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEI
AIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAP
FEGEDEDELFQSIMEHNVAYPKSMSKEAVAICKGLMTKHPGKRLGCGPEGERDIKEHAFFRYIDWEKLERKEIQPPYKPKARDKRDTSNF

--------------------------------------------------------------

>33002_33002_3_GGA2-PRKCB_GGA2_chr16_23502998_ENST00000567468_PRKCB_chr16_23999829_ENST00000303531_length(amino acids)=763AA_BP=158
MAATAVAAAVAGTESAQGPPGPAASLELWLNKATDPSMSEQDWSAIQNFCEQVNTDPNGPTHAPWLLAHKIQSPQEKEALYALTVLEMCM
NHCGEKFHSEVAKFRFLNELIKVLSPKYLGSWATGKVKGRVIEILFSWTVWFPEDIKIRDAYQMLKKQVCCFVVHKRCHEFVTFSCPGAD
KGPASDDPRSKHKFKIHTYSSPTFCDHCGSLLYGLIHQGMKCDTCMMNVHKRCVMNVPSLCGTDHTERRGRIYIQAHIDRDVLIVLVRDA
KNLVPMDPNGLSDPYVKLKLIPDPKSESKQKTKTIKCSLNPEWNETFRFQLKESDKDRRLSVEIWDWDLTSRNDFMGSLSFGISELQKAS
VDGWFKLLSQEEGEYFNVPVPPEGSEANEELRQKFERAKISQGTKVPEEKTTNTVSKFDNNGNRDRMKLTDFNFLMVLGKGSFGKVMLSE
RKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPGKPPFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEI
AIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAP
FEGEDEDELFQSIMEHNVAYPKSMSKEAVAICKGLMTKHPGKRLGCGPEGERDIKEHAFFRYIDWEKLERKEIQPPYKPKACGRNAENFD

--------------------------------------------------------------

>33002_33002_4_GGA2-PRKCB_GGA2_chr16_23502998_ENST00000567468_PRKCB_chr16_23999829_ENST00000321728_length(amino acids)=761AA_BP=158
MAATAVAAAVAGTESAQGPPGPAASLELWLNKATDPSMSEQDWSAIQNFCEQVNTDPNGPTHAPWLLAHKIQSPQEKEALYALTVLEMCM
NHCGEKFHSEVAKFRFLNELIKVLSPKYLGSWATGKVKGRVIEILFSWTVWFPEDIKIRDAYQMLKKQVCCFVVHKRCHEFVTFSCPGAD
KGPASDDPRSKHKFKIHTYSSPTFCDHCGSLLYGLIHQGMKCDTCMMNVHKRCVMNVPSLCGTDHTERRGRIYIQAHIDRDVLIVLVRDA
KNLVPMDPNGLSDPYVKLKLIPDPKSESKQKTKTIKCSLNPEWNETFRFQLKESDKDRRLSVEIWDWDLTSRNDFMGSLSFGISELQKAS
VDGWFKLLSQEEGEYFNVPVPPEGSEANEELRQKFERAKISQGTKVPEEKTTNTVSKFDNNGNRDRMKLTDFNFLMVLGKGSFGKVMLSE
RKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPGKPPFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEI
AIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAP
FEGEDEDELFQSIMEHNVAYPKSMSKEAVAICKGLMTKHPGKRLGCGPEGERDIKEHAFFRYIDWEKLERKEIQPPYKPKARDKRDTSNF

--------------------------------------------------------------

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Fusion Protein Functional Features

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr16:23502998/chr16:23999829)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
GGA2 Q9UJY4	.
FUNCTION: Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF-dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (DXXLL) motif (PubMed:10747088). Mediates export of the GPCR receptor ADRA2B to the cell surface (PubMed:27901063). Regulates retrograde transport of phosphorylated form of BACE1 from endosomes to the trans-Golgi network (PubMed:15615712). {ECO:0000269\|PubMed:10747088, ECO:0000269\|PubMed:15615712, ECO:0000269\|PubMed:27901063}.	FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page
* Minus value of BPloci means that the break pointn is located before the CDS.

- Retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Tgene

PRKCB

chr16:23502998

chr16:23999829

ENST00000303531

158_275

68.33333333333333

674.0

Domain

Tgene

PRKCB

chr16:23502998

chr16:23999829

ENST00000303531

342_600

68.33333333333333

674.0

Domain

Protein kinase

Tgene

PRKCB

chr16:23502998

chr16:23999829

ENST00000303531

601_671

68.33333333333333

674.0

Domain

AGC-kinase C-terminal

Tgene

PRKCB

chr16:23502998

chr16:23999829

ENST00000321728

158_275

68.33333333333333

672.0

Domain

Tgene

PRKCB

chr16:23502998

chr16:23999829

ENST00000321728

342_600

68.33333333333333

672.0

Domain

Protein kinase

Tgene

PRKCB

chr16:23502998

chr16:23999829

ENST00000321728

601_671

68.33333333333333

672.0

Domain

AGC-kinase C-terminal

Tgene

PRKCB

chr16:23502998

chr16:23999829

ENST00000498058

158_275

58.0

Domain

Tgene

PRKCB

chr16:23502998

chr16:23999829

ENST00000498058

342_600

58.0

Domain

Protein kinase

Tgene

PRKCB

chr16:23502998

chr16:23999829

ENST00000498058

601_671

58.0

Domain

AGC-kinase C-terminal

Tgene

PRKCB

chr16:23502998

chr16:23999829

ENST00000303531

348_356

68.33333333333333

674.0

Nucleotide binding

ATP

Tgene

PRKCB

chr16:23502998

chr16:23999829

ENST00000321728

348_356

68.33333333333333

672.0

Nucleotide binding

ATP

Tgene

PRKCB

chr16:23502998

chr16:23999829

ENST00000498058

348_356

58.0

Nucleotide binding

ATP

Tgene

PRKCB

chr16:23502998

chr16:23999829

ENST00000303531

101_151

68.33333333333333

674.0

Zinc finger

Phorbol-ester/DAG-type 2

Tgene

PRKCB

chr16:23502998

chr16:23999829

ENST00000321728

101_151

68.33333333333333

672.0

Zinc finger

Phorbol-ester/DAG-type 2

Tgene

PRKCB

chr16:23502998

chr16:23999829

ENST00000498058

101_151

58.0

Zinc finger

Phorbol-ester/DAG-type 2

Tgene

PRKCB

chr16:23502998

chr16:23999829

ENST00000498058

36_86

58.0

Zinc finger

Phorbol-ester/DAG-type 1

- Not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

GGA2

chr16:23502998

chr16:23999829

ENST00000309859

188_315

158.33333333333334

614.0

Domain

GAT

Hgene

GGA2

chr16:23502998

chr16:23999829

ENST00000309859

33_163

158.33333333333334

614.0

Domain

VHS

Hgene

GGA2

chr16:23502998

chr16:23999829

ENST00000309859

484_605

158.33333333333334

614.0

Domain

GAE

Hgene

GGA2

chr16:23502998

chr16:23999829

ENST00000309859

316_483

158.33333333333334

614.0

Region

Note=Unstructured hinge

Tgene

PRKCB

chr16:23502998

chr16:23999829

ENST00000303531

36_86

68.33333333333333

674.0

Zinc finger

Phorbol-ester/DAG-type 1

Tgene

PRKCB

chr16:23502998

chr16:23999829

ENST00000321728

36_86

68.33333333333333

672.0

Zinc finger

Phorbol-ester/DAG-type 1

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Fusion Protein Structures

PDB and CIF files of the predicted fusion proteins
* Here we show the 3D structure of the fusion proteins using Mol*. AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Model confidence is shown from the pLDDT values per residue. pLDDT corresponds to the model’s prediction of its score on the local Distance Difference Test. It is a measure of local accuracy (from AlphfaFold website). To color code individual residues, we transformed individual PDB files into CIF format.

Fusion protein PDB link (fusion AA seq ID in FusionPDB)	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	AA seq	Len(AA seq)
PDB file >>>1539_GGA2_23502998_PRKCB_23999829_ranked_0.pdb	GGA2	23502998	23502998	ENST00000303531	PRKCB	chr16	23999829	+	MAATAVAAAVAGTESAQGPPGPAASLELWLNKATDPSMSEQDWSAIQNFCEQVNTDPNGPTHAPWLLAHKIQSPQEKEALYALTVLEMCM NHCGEKFHSEVAKFRFLNELIKVLSPKYLGSWATGKVKGRVIEILFSWTVWFPEDIKIRDAYQMLKKQVCCFVVHKRCHEFVTFSCPGAD KGPASDDPRSKHKFKIHTYSSPTFCDHCGSLLYGLIHQGMKCDTCMMNVHKRCVMNVPSLCGTDHTERRGRIYIQAHIDRDVLIVLVRDA KNLVPMDPNGLSDPYVKLKLIPDPKSESKQKTKTIKCSLNPEWNETFRFQLKESDKDRRLSVEIWDWDLTSRNDFMGSLSFGISELQKAS VDGWFKLLSQEEGEYFNVPVPPEGSEANEELRQKFERAKISQGTKVPEEKTTNTVSKFDNNGNRDRMKLTDFNFLMVLGKGSFGKVMLSE RKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPGKPPFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEI AIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAP FEGEDEDELFQSIMEHNVAYPKSMSKEAVAICKGLMTKHPGKRLGCGPEGERDIKEHAFFRYIDWEKLERKEIQPPYKPKACGRNAENFD	763

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pLDDT score distribution

pLDDT score distribution of the predicted wild-type structures of two partner proteins from AlphaFold2
* AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100.

GGA2_pLDDT.png

PRKCB_pLDDT.png

pLDDT score distribution of the predicted fusion protein structures from AlphaFold2
* AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100.

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Ramachandran Plot of Fusion Protein Structure

Ramachandran plot of the torsional angles - phi (φ)and psi (ψ) - of the residues (amino acids) contained in this fusion protein peptide.

Fusion AA seq ID in FusionPDB and their Ramachandran plots

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Fusion Protein-Protein Interaction

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type from validated records (BIOGRID-3.4.160)

Gene

PPI interactors

Protein-protein interactors based on sequence similarity (STRING)

Gene	STRING network
GGA2
PRKCB

- Retained interactions in fusion protein (protein functional feature from UniProt).

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost interactions due to fusion (protein functional feature from UniProt).

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

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Related Drugs to GGA2-PRKCB

Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)

Hgene

Tgene

Drug

Source

PMID

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Related Diseases to GGA2-PRKCB

Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)

Hgene

Tgene

Disease

Source

PMID

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source