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	Fusion Gene Summary
	Fusion Gene Sample Information
	Fusion ORF Analysis
	Fusion Amino Acid Sequences
	Fusion Protein Functional Features
	Fusion Protein-Protein Interaction
	Related drugs with this fusion protein
	Related disease with this fusion protein

Fusion Protein:GRIK2-EYS

Fusion Protein Summary

Fusion gene summary

Fusion partner gene information	Fusion gene name: GRIK2-EYS
	FusionPDB ID: 34786
	FusionGDB2.0 ID: 34786
		Hgene	Tgene
	Gene symbol	GRIK2	EYS
	Gene ID	2901	346007
	Gene name	glutamate ionotropic receptor kainate type subunit 5	eyes shut homolog
	Synonyms	EAA2\|GRIK2\|GluK5\|KA2	C6orf178\|C6orf179\|C6orf180\|EGFL10\|EGFL11\|RP25\|SPAM\|bA166P24.2\|bA307F22.3\|bA74E24.1\|dJ1018A4.2\|dJ22I17.2\|dJ303F19.1
	Cytomap	19q13.2	6q12
	Type of gene	protein-coding	protein-coding
	Description	glutamate receptor ionotropic, kainate 5excitatory amino acid receptor 2glutamate receptor KA2	protein eyes shut homologEGF-like-domain, multiple 10EGF-like-domain, multiple 11epidermal growth factor-like protein 10epidermal growth factor-like protein 11protein spacemaker homolog
	Modification date	20200313	20200313
	UniProtAcc	Q13002	Q5T1H1
Ensembl transtripts involved in fusion gene	ENST ids	ENST00000318991, ENST00000358361, ENST00000369137, ENST00000369138, ENST00000413795, ENST00000421544, ENST00000369134,	ENST00000342421, ENST00000370618, ENST00000393380, ENST00000486069, ENST00000370616, ENST00000370621, ENST00000503581,
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)	* DoF score	9 X 4 X 6=216	36 X 24 X 15=12960
	# samples	10	38
	** MAII score	log2(10/216*10)=-1.11103131238874 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(38/12960*10)=-5.09192248944104 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context (manual curation of fusion genes in FusionPDB)	PubMed: GRIK2 [Title/Abstract] AND EYS [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)	GRIK2(101847268)-EYS(65767620), # samples:1
Anticipated loss of major functional domain due to fusion event.	GRIK2-EYS seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. GRIK2-EYS seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. GRIK2-EYS seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. GRIK2-EYS seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner

Gene

GO ID

GO term

PubMed ID

Fusion gene breakpoints across GRIK2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across EYS (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

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Fusion Gene Sample Information

Fusion gene information from FusionGDB2.0.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	LGG	TCGA-TM-A7CF-01A	GRIK2	chr6	101847268	-	EYS	chr6	65767620	-

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Fusion ORF Analysis

Fusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000413795	GRIK2	chr6	101847268	-	ENST00000503581	EYS	chr6	65767620	-	8633	605	391	8016	2541
ENST00000413795	GRIK2	chr6	101847268	-	ENST00000370621	EYS	chr6	65767620	-	8540	605	391	8079	2562
ENST00000413795	GRIK2	chr6	101847268	-	ENST00000370616	EYS	chr6	65767620	-	8080	605	391	8079	2563
ENST00000369138	GRIK2	chr6	101847268	-	ENST00000503581	EYS	chr6	65767620	-	8633	605	391	8016	2541
ENST00000369138	GRIK2	chr6	101847268	-	ENST00000370621	EYS	chr6	65767620	-	8540	605	391	8079	2562
ENST00000369138	GRIK2	chr6	101847268	-	ENST00000370616	EYS	chr6	65767620	-	8080	605	391	8079	2563
ENST00000421544	GRIK2	chr6	101847268	-	ENST00000503581	EYS	chr6	65767620	-	8633	605	391	8016	2541
ENST00000421544	GRIK2	chr6	101847268	-	ENST00000370621	EYS	chr6	65767620	-	8540	605	391	8079	2562
ENST00000421544	GRIK2	chr6	101847268	-	ENST00000370616	EYS	chr6	65767620	-	8080	605	391	8079	2563
ENST00000358361	GRIK2	chr6	101847268	-	ENST00000503581	EYS	chr6	65767620	-	8628	600	386	8011	2541
ENST00000358361	GRIK2	chr6	101847268	-	ENST00000370621	EYS	chr6	65767620	-	8535	600	386	8074	2562
ENST00000358361	GRIK2	chr6	101847268	-	ENST00000370616	EYS	chr6	65767620	-	8075	600	386	8074	2563
ENST00000318991	GRIK2	chr6	101847268	-	ENST00000503581	EYS	chr6	65767620	-	8143	115	0	7526	2508
ENST00000318991	GRIK2	chr6	101847268	-	ENST00000370621	EYS	chr6	65767620	-	8050	115	0	7589	2529
ENST00000318991	GRIK2	chr6	101847268	-	ENST00000370616	EYS	chr6	65767620	-	7590	115	0	7589	2529
ENST00000369137	GRIK2	chr6	101847268	-	ENST00000503581	EYS	chr6	65767620	-	8143	115	0	7526	2508
ENST00000369137	GRIK2	chr6	101847268	-	ENST00000370621	EYS	chr6	65767620	-	8050	115	0	7589	2529
ENST00000369137	GRIK2	chr6	101847268	-	ENST00000370616	EYS	chr6	65767620	-	7590	115	0	7589	2529

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000413795	ENST00000503581	GRIK2	chr6	101847268	-	EYS	chr6	65767620	-	0.000257583	0.99974245
ENST00000413795	ENST00000370621	GRIK2	chr6	101847268	-	EYS	chr6	65767620	-	0.000475493	0.9995245
ENST00000413795	ENST00000370616	GRIK2	chr6	101847268	-	EYS	chr6	65767620	-	0.000615207	0.99938476
ENST00000369138	ENST00000503581	GRIK2	chr6	101847268	-	EYS	chr6	65767620	-	0.000257583	0.99974245
ENST00000369138	ENST00000370621	GRIK2	chr6	101847268	-	EYS	chr6	65767620	-	0.000475493	0.9995245
ENST00000369138	ENST00000370616	GRIK2	chr6	101847268	-	EYS	chr6	65767620	-	0.000615207	0.99938476
ENST00000421544	ENST00000503581	GRIK2	chr6	101847268	-	EYS	chr6	65767620	-	0.000257583	0.99974245
ENST00000421544	ENST00000370621	GRIK2	chr6	101847268	-	EYS	chr6	65767620	-	0.000475493	0.9995245
ENST00000421544	ENST00000370616	GRIK2	chr6	101847268	-	EYS	chr6	65767620	-	0.000615207	0.99938476
ENST00000358361	ENST00000503581	GRIK2	chr6	101847268	-	EYS	chr6	65767620	-	0.000254765	0.9997452
ENST00000358361	ENST00000370621	GRIK2	chr6	101847268	-	EYS	chr6	65767620	-	0.000471026	0.999529
ENST00000358361	ENST00000370616	GRIK2	chr6	101847268	-	EYS	chr6	65767620	-	0.000608432	0.99939156
ENST00000318991	ENST00000503581	GRIK2	chr6	101847268	-	EYS	chr6	65767620	-	0.000134271	0.9998658
ENST00000318991	ENST00000370621	GRIK2	chr6	101847268	-	EYS	chr6	65767620	-	0.000252242	0.9997478
ENST00000318991	ENST00000370616	GRIK2	chr6	101847268	-	EYS	chr6	65767620	-	0.000327008	0.999673
ENST00000369137	ENST00000503581	GRIK2	chr6	101847268	-	EYS	chr6	65767620	-	0.000134271	0.9998658
ENST00000369137	ENST00000370621	GRIK2	chr6	101847268	-	EYS	chr6	65767620	-	0.000252242	0.9997478
ENST00000369137	ENST00000370616	GRIK2	chr6	101847268	-	EYS	chr6	65767620	-	0.000327008	0.999673

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Fusion Amino Acid Sequences

For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

>34786_34786_1_GRIK2-EYS_GRIK2_chr6_101847268_ENST00000318991_EYS_chr6_65767620_ENST00000370616_length(amino acids)=2529AA_BP=38
MKIIFPILSNPVFRRTVKLLLCLLWIGYSQGTTHVLRFGTQCEIDIDECASHPCKNGATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYV
GIRCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEINECDSD
PCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDCLFLSCQDYGDCE
DMVNNFRCICRPGFSGSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCELDVNKCKISPCLDEENCVYRTDGYNCLCAPGY
TGINCEINLDECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETNANDCLSNPCLHGRCTELINEYPCSCDADGTSTQCKIKINDCTSI
PCMNEGFCQKSAHGFTCICPRGYTGAYCEKSIDNCAEPELNSVICLNGGICVDGPGHTFDCRCLPGFSGQFCEININECSSSPCLHGADC
EDHINGYVCKCQPGWSGHHCENELECIPNSCVHELCMENEPGSTCLCTPGFMTCSIGLLCGDEIRRITCLTPIFQRTDPISTQTYTIPPS
ETLVSSFPSIKATRIPAIMDTYPVDQGPKQTGIVKHDILPTTGLATLRISTPLESYLLQELIVTRELSAKHSLLSSADVSSSRFLNFGIR
DPAQIVQDKTSVSHMPIRTSAATLGFFFPDRRARTPFIMSSLMSDFIFPTQSLLFENCQTVALSATPTTSVIRSIPGADIELNRQSLLSR
GFLLIAASISATPVVSRGAQEDIEEYSADSLISRREHWRLLSPSMSPIFPAKVIISKQVTILNSSALHRFSTKAFNPSEYQAITEASSNQ
RLTNIKSQAADSLRELSQTCATCSMTEIKSSREFSDQVLHSKQSHFYETFWMNSAILASWYALMGAQTITSGHSFSSATEITPSVAFTEV
PSLFPSKKSAKRTILSSSLEESITLSSNLDVNLCLDKTCLSIVPSQTISSDLMNSDLTSKMTTDELSVSENILKLLKIRQYGITMGPTEV
LNQESLLDMEKSKGSHTLFKLHPSDSSLDFELNLQIYPDVTLKTYSEITHANDFKNNLPPLTGSVPDFSEVTTNVAFYTVSATPALSIQT
SSSMSVIRPDWPYFTDYMTSLKKEVKTSSEWSKWELQPSVQYQEFPTASRHLPFTRSLTLSSLESILAPQRLMISDFSCVRYYGDSYLEF
QNVALNPQNNISLEFQTFSSYGLLLYVKQDSNLVDGFFIQLFIENGTLKYHFYCPGEAKFKSINTTVRVDNGQKYTLLIRQELDPCNAEL
TILGRNTQICESINHVLGKPLPKSGSVFIGGFPDLHGKIQMPVPVKNFTGCIEVIEINNWRSFIPSKAVKNYHINNCRSQGFMLSPTASF
VDASDVTQGVDTMWTSVSPSVAAPSVCQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKDAGLFFPSFNGNSYLELPFLKFVLE
KEHNRTVTIYLTIKTNSLNGTILYSNGNNCGKQFLHLFLVEGRPSVKYGCGNSQNILTVSANYSINTNAFTPITIRYTTPVGSPGVVCMI
EMTADGKPPVQKKDTEISHASQAYFESMFLGHIPANVQIHKKAGPVYGFRGCILDLQVNNKEFFIIDEARHGKNIENCHVPWCAHHLCRN
NGTCISDNENLFCECPRLYSGKLCQFASCENNPCGNGATCVPKSGTDIVCLCPYGRSGPLCTDAINITQPRFSGTDAFGYTSFLAYSRIS
DISFHYEFHLKFQLANNHSALQNNLIFFTGQKGHGLNGDDFLAVGLLNGSVVYSYNLGSGIASIRSEPLNLSLGVHTVHLGKFFQEGWLK
VDDHKNKSIIAPGRLVGLNVFSQFYVGGYSEYTPDLLPNGADFKNGFQGCIFTLQVRTEKDGHFRGLGNPEGHPNAGRSVGQCHASPCSL
MKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPHGYTCFCPLGTTGIYCEQALILIVILEKPKPAER
KVKKEALSISDPSFRSNELSWMSFASFHVRKKTHIQLQFQPLAADGILFYAAQHLKAQSGDFLCISLVNSSVQLRYNLGDRTIILETLQK
VTINGSTWHIIKAGRVGAEGYLDLDGINVTEKASTKMSSLDTNTDFYIGGVSSLNLVNPMAIENEPVGFQGCIRQVIINNQELQLTEFGA
KGGSNVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNLCLHQSLCIPDQSFSYSCLCTLGWVGRYCENKTSFS
TAKFMGNSYIKYIDPNYRMRNLQFTTISLNFSTTKTEGLIVWMGIAQNEENDFLAIGLHNQTLKIAVNLGERISVPMSYNNGTFCCNKWH
HVVVIQNQTLIKAYINNSLILSEDIDPHKNFVALNYDGICYLGGFEYGRKVNIVTQEIFKTNFVGKIKDVVFFQEPKNIELIKLEGYNVY

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>34786_34786_2_GRIK2-EYS_GRIK2_chr6_101847268_ENST00000318991_EYS_chr6_65767620_ENST00000370621_length(amino acids)=2529AA_BP=38
MKIIFPILSNPVFRRTVKLLLCLLWIGYSQGTTHVLRFGTQCEIDIDECASHPCKNGATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYV
GIRCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEINECDSD
PCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDCLFLSCQDYGDCE
DMVNNFRCICRPGFSGSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCELDVNKCKISPCLDEENCVYRTDGYNCLCAPGY
TGINCEINLDECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETNANDCLSNPCLHGRCTELINEYPCSCDADGTSTQCKIKINDCTSI
PCMNEGFCQKSAHGFTCICPRGYTGAYCEKSIDNCAEPELNSVICLNGGICVDGPGHTFDCRCLPGFSGQFCEININECSSSPCLHGADC
EDHINGYVCKCQPGWSGHHCENELECIPNSCVHELCMENEPGSTCLCTPGFMTCSIGLLCGDEIRRITCLTPIFQRTDPISTQTYTIPPS
ETLVSSFPSIKATRIPAIMDTYPVDQGPKQTGIVKHDILPTTGLATLRISTPLESYLLQELIVTRELSAKHSLLSSADVSSSRFLNFGIR
DPAQIVQDKTSVSHMPIRTSAATLGFFFPDRRARTPFIMSSLMSDFIFPTQSLLFENCQTVALSATPTTSVIRSIPGADIELNRQSLLSR
GFLLIAASISATPVVSRGAQEDIEEYSADSLISRREHWRLLSPSMSPIFPAKVIISKQVTILNSSALHRFSTKAFNPSEYQAITEASSNQ
RLTNIKSQAADSLRELSQTCATCSMTEIKSSREFSDQVLHSKQSHFYETFWMNSAILASWYALMGAQTITSGHSFSSATEITPSVAFTEV
PSLFPSKKSAKRTILSSSLEESITLSSNLDVNLCLDKTCLSIVPSQTISSDLMNSDLTSKMTTDELSVSENILKLLKIRQYGITMGPTEV
LNQESLLDMEKSKGSHTLFKLHPSDSSLDFELNLQIYPDVTLKTYSEITHANDFKNNLPPLTGSVPDFSEVTTNVAFYTVSATPALSIQT
SSSMSVIRPDWPYFTDYMTSLKKEVKTSSEWSKWELQPSVQYQEFPTASRHLPFTRSLTLSSLESILAPQRLMISDFSCVRYYGDSYLEF
QNVALNPQNNISLEFQTFSSYGLLLYVKQDSNLVDGFFIQLFIENGTLKYHFYCPGEAKFKSINTTVRVDNGQKYTLLIRQELDPCNAEL
TILGRNTQICESINHVLGKPLPKSGSVFIGGFPDLHGKIQMPVPVKNFTGCIEVIEINNWRSFIPSKAVKNYHINNCRSQGFMLSPTASF
VDASDVTQGVDTMWTSVSPSVAAPSVCQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKDAGLFFPSFNGNSYLELPFLKFVLE
KEHNRTVTIYLTIKTNSLNGTILYSNGNNCGKQFLHLFLVEGRPSVKYGCGNSQNILTVSANYSINTNAFTPITIRYTTPVGSPGVVCMI
EMTADGKPPVQKKDTEISHASQAYFESMFLGHIPANVQIHKKAGPVYGFRGCILDLQVNNKEFFIIDEARHGKNIENCHVPWCAHHLCRN
NGTCISDNENLFCECPRLYSGKLCQFASCENNPCGNGATCVPKSGTDIVCLCPYGRSGPLCTDAINITQPRFSGTDAFGYTSFLAYSRIS
DISFHYEFHLKFQLANNHSALQNNLIFFTGQKGHGLNGDDFLAVGLLNGSVVYSYNLGSGIASIRSEPLNLSLGVHTVHLGKFFQEGWLK
VDDHKNKSIIAPGRLVGLNVFSQFYVGGYSEYTPDLLPNGADFKNGFQGCIFTLQVRTEKDGHFRGLGNPEGHPNAGRSVGQCHASPCSL
MKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPHGYTCFCPLGTTGIYCEQALILIVILEKPKPAER
KVKKEALSISDPSFRSNELSWMSFASFHVRKKTHIQLQFQPLAADGILFYAAQHLKAQSGDFLCISLVNSSVQLRYNLGDRTIILETLQK
VTINGSTWHIIKAGRVGAEGYLDLDGINVTEKASTKMSSLDTNTDFYIGGVSSLNLVNPMAIENEPVGFQGCIRQVIINNQELQLTEFGA
KGGSNVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNLCLHQSLCIPDQSFSYSCLCTLGWVGRYCENKTSFS
TAKFMGNSYIKYIDPNYRMRNLQFTTISLNFSTTKTEGLIVWMGIAQNEENDFLAIGLHNQTLKIAVNLGERISVPMSYNNGTFCCNKWH
HVVVIQNQTLIKAYINNSLILSEDIDPHKNFVALNYDGICYLGGFEYGRKVNIVTQEIFKTNFVGKIKDVVFFQEPKNIELIKLEGYNVY

--------------------------------------------------------------

>34786_34786_3_GRIK2-EYS_GRIK2_chr6_101847268_ENST00000318991_EYS_chr6_65767620_ENST00000503581_length(amino acids)=2508AA_BP=38
MKIIFPILSNPVFRRTVKLLLCLLWIGYSQGTTHVLRFGTQCEIDIDECASHPCKNGATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYV
GIRCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEINECDSD
PCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDCLFLSCQDYGDCE
DMVNNFRCICRPGFSGSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCELDVNKCKISPCLDEENCVYRTDGYNCLCAPGY
TGINCEINLDECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETNANDCLSNPCLHGRCTELINEYPCSCDADGTSTQCKIKINDCTSI
PCMNEGFCQKSAHGFTCICPRGYTGAYCEKSIDNCAEPELNSVICLNGGICVDGPGHTFDCRCLPGFSGQFCEININECSSSPCLHGADC
EDHINGYVCKCQPGWSGHHCENELECIPNSCVHELCMENEPGSTCLCTPGFMTCSIGLLCGDEIRRITCLTPIFQRTDPISTQTYTIPPS
ETLVSSFPSIKATRIPAIMDTYPVDQGPKQTGIVKHDILPTTGLATLRISTPLESYLLQELIVTRELSAKHSLLSSADVSSSRFLNFGIR
DPAQIVQDKTSVSHMPIRTSAATLGFFFPDRRARTPFIMSSLMSDFIFPTQSLLFENCQTVALSATPTTSVIRSIPGADIELNRQSLLSR
GFLLIAASISATPVVSRGAQEDIEEYSADSLISRREHWRLLSPSMSPIFPAKVIISKQVTILNSSALHRFSTKAFNPSEYQAITEASSNQ
RLTNIKSQAADSLRELSQTCATCSMTEIKSSREFSDQVLHSKQSHFYETFWMNSAILASWYALMGAQTITSGHSFSSATEITPSVAFTEV
PSLFPSKKSAKRTILSSSLEESITLSSNLDVNLCLDKTCLSIVPSQTISSDLMNSDLTSKMTTDELSVSENILKLLKIRQYGITMGPTEV
LNQESLLDMEKSKGSHTLFKLHPSDSSLDFELNLQIYPDVTLKTYSEITHANDFKNNLPPLTGSVPDFSEVTTNVAFYTVSATPALSIQT
SSSMSVIRPDWPYFTDYMTSLKKEVKTSSEWSKWELQPSVQYQEFPTASRHLPFTRSLTLSSLESILAPQRLMISDFSCVRYYGDSYLEF
QNVALNPQNNISLEFQTFSSYGLLLYVKQDSNLVDGFFIQLFIENGTLKYHFYCPGEAKFKSINTTVRVDNGQKYTLLIRQELDPCNAEL
TILGRNTQICESINHVLGKPLPKSGSVFIGGFPDLHGKIQMPVPVKNFTGCIEVIEINNWRSFIPSKAVKNYHINNCRSQGFMLSPTASF
VDASDVTQGVDTMWTSVSPSVAAPSVCQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKDAGLFFPSFNGNSYLELPFLKFVLE
KEHNRTVTIYLTIKTNSLNGTILYSNGNNCGKQFLHLFLVEGRPSVKYGCGNSQNILTVSANYSINTNAFTPITIRYTTPVGSPGVVCMI
EMTADGKPPVQKKDTEISHASQAYFESMFLGHIPANVQIHKKAGPVYGFRGCILDLQVNNKEFFIIDEARHGKNIENCHVPWCAHHLCRN
NGTCISDNENLFCECPRLYSGKLCQFASCENNPCGNGATCVPKSGTDIVCLCPYGRSGPLCTDAINITQPRFSGTDAFGYTSFLAYSRIS
DISFHYEFHLKFQLANNHSALQNNLIFFTGQKGHGLNGDDFLAVGLLNGSVVYSYNLGSGIASIRSEPLNLSLGVHTVHLGKFFQEGWLK
VDDHKNKSIIAPGRLVGLNVFSQFYVGGYSEYTPDLLPNGADFKNGFQGCIFTLQVRTEKDGHFRGLGNPEGHPNAGRSVGQCHASPCSL
MKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPHGYTCFCPLGTTGIYCEQALSISDPSFRSNELSW
MSFASFHVRKKTHIQLQFQPLAADGILFYAAQHLKAQSGDFLCISLVNSSVQLRYNLGDRTIILETLQKVTINGSTWHIIKAGRVGAEGY
LDLDGINVTEKASTKMSSLDTNTDFYIGGVSSLNLVNPMAIENEPVGFQGCIRQVIINNQELQLTEFGAKGGSNVGDCDGTACGYNTCRN
GGECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNLCLHQSLCIPDQSFSYSCLCTLGWVGRYCENKTSFSTAKFMGNSYIKYIDPNYRMRN
LQFTTISLNFSTTKTEGLIVWMGIAQNEENDFLAIGLHNQTLKIAVNLGERISVPMSYNNGTFCCNKWHHVVVIQNQTLIKAYINNSLIL

--------------------------------------------------------------

>34786_34786_4_GRIK2-EYS_GRIK2_chr6_101847268_ENST00000358361_EYS_chr6_65767620_ENST00000370616_length(amino acids)=2563AA_BP=71
MRSPLDASSFLPEPRSRTLDRGSGCRACGHRNTMKIIFPILSNPVFRRTVKLLLCLLWIGYSQGTTHVLRFGTQCEIDIDECASHPCKNG
ATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMNPCKNN
STCTDLYKSYRCECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDAN
QHCICREEFEGKNCEIDVKDCLFLSCQDYGDCEDMVNNFRCICRPGFSGSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFC
ELDVNKCKISPCLDEENCVYRTDGYNCLCAPGYTGINCEINLDECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETNANDCLSNPCLH
GRCTELINEYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTCICPRGYTGAYCEKSIDNCAEPELNSVICLNGGICVDGPGH
TFDCRCLPGFSGQFCEININECSSSPCLHGADCEDHINGYVCKCQPGWSGHHCENELECIPNSCVHELCMENEPGSTCLCTPGFMTCSIG
LLCGDEIRRITCLTPIFQRTDPISTQTYTIPPSETLVSSFPSIKATRIPAIMDTYPVDQGPKQTGIVKHDILPTTGLATLRISTPLESYL
LQELIVTRELSAKHSLLSSADVSSSRFLNFGIRDPAQIVQDKTSVSHMPIRTSAATLGFFFPDRRARTPFIMSSLMSDFIFPTQSLLFEN
CQTVALSATPTTSVIRSIPGADIELNRQSLLSRGFLLIAASISATPVVSRGAQEDIEEYSADSLISRREHWRLLSPSMSPIFPAKVIISK
QVTILNSSALHRFSTKAFNPSEYQAITEASSNQRLTNIKSQAADSLRELSQTCATCSMTEIKSSREFSDQVLHSKQSHFYETFWMNSAIL
ASWYALMGAQTITSGHSFSSATEITPSVAFTEVPSLFPSKKSAKRTILSSSLEESITLSSNLDVNLCLDKTCLSIVPSQTISSDLMNSDL
TSKMTTDELSVSENILKLLKIRQYGITMGPTEVLNQESLLDMEKSKGSHTLFKLHPSDSSLDFELNLQIYPDVTLKTYSEITHANDFKNN
LPPLTGSVPDFSEVTTNVAFYTVSATPALSIQTSSSMSVIRPDWPYFTDYMTSLKKEVKTSSEWSKWELQPSVQYQEFPTASRHLPFTRS
LTLSSLESILAPQRLMISDFSCVRYYGDSYLEFQNVALNPQNNISLEFQTFSSYGLLLYVKQDSNLVDGFFIQLFIENGTLKYHFYCPGE
AKFKSINTTVRVDNGQKYTLLIRQELDPCNAELTILGRNTQICESINHVLGKPLPKSGSVFIGGFPDLHGKIQMPVPVKNFTGCIEVIEI
NNWRSFIPSKAVKNYHINNCRSQGFMLSPTASFVDASDVTQGVDTMWTSVSPSVAAPSVCQQDVCHNGGTCHAIFLSSGIVSFQCDCPLH
FTGRFCEKDAGLFFPSFNGNSYLELPFLKFVLEKEHNRTVTIYLTIKTNSLNGTILYSNGNNCGKQFLHLFLVEGRPSVKYGCGNSQNIL
TVSANYSINTNAFTPITIRYTTPVGSPGVVCMIEMTADGKPPVQKKDTEISHASQAYFESMFLGHIPANVQIHKKAGPVYGFRGCILDLQ
VNNKEFFIIDEARHGKNIENCHVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFASCENNPCGNGATCVPKSGTDIVCLCPYGRS
GPLCTDAINITQPRFSGTDAFGYTSFLAYSRISDISFHYEFHLKFQLANNHSALQNNLIFFTGQKGHGLNGDDFLAVGLLNGSVVYSYNL
GSGIASIRSEPLNLSLGVHTVHLGKFFQEGWLKVDDHKNKSIIAPGRLVGLNVFSQFYVGGYSEYTPDLLPNGADFKNGFQGCIFTLQVR
TEKDGHFRGLGNPEGHPNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPH
GYTCFCPLGTTGIYCEQALILIVILEKPKPAERKVKKEALSISDPSFRSNELSWMSFASFHVRKKTHIQLQFQPLAADGILFYAAQHLKA
QSGDFLCISLVNSSVQLRYNLGDRTIILETLQKVTINGSTWHIIKAGRVGAEGYLDLDGINVTEKASTKMSSLDTNTDFYIGGVSSLNLV
NPMAIENEPVGFQGCIRQVIINNQELQLTEFGAKGGSNVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNLCL
HQSLCIPDQSFSYSCLCTLGWVGRYCENKTSFSTAKFMGNSYIKYIDPNYRMRNLQFTTISLNFSTTKTEGLIVWMGIAQNEENDFLAIG
LHNQTLKIAVNLGERISVPMSYNNGTFCCNKWHHVVVIQNQTLIKAYINNSLILSEDIDPHKNFVALNYDGICYLGGFEYGRKVNIVTQE

--------------------------------------------------------------

>34786_34786_5_GRIK2-EYS_GRIK2_chr6_101847268_ENST00000358361_EYS_chr6_65767620_ENST00000370621_length(amino acids)=2562AA_BP=71
MRSPLDASSFLPEPRSRTLDRGSGCRACGHRNTMKIIFPILSNPVFRRTVKLLLCLLWIGYSQGTTHVLRFGTQCEIDIDECASHPCKNG
ATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMNPCKNN
STCTDLYKSYRCECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDAN
QHCICREEFEGKNCEIDVKDCLFLSCQDYGDCEDMVNNFRCICRPGFSGSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFC
ELDVNKCKISPCLDEENCVYRTDGYNCLCAPGYTGINCEINLDECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETNANDCLSNPCLH
GRCTELINEYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTCICPRGYTGAYCEKSIDNCAEPELNSVICLNGGICVDGPGH
TFDCRCLPGFSGQFCEININECSSSPCLHGADCEDHINGYVCKCQPGWSGHHCENELECIPNSCVHELCMENEPGSTCLCTPGFMTCSIG
LLCGDEIRRITCLTPIFQRTDPISTQTYTIPPSETLVSSFPSIKATRIPAIMDTYPVDQGPKQTGIVKHDILPTTGLATLRISTPLESYL
LQELIVTRELSAKHSLLSSADVSSSRFLNFGIRDPAQIVQDKTSVSHMPIRTSAATLGFFFPDRRARTPFIMSSLMSDFIFPTQSLLFEN
CQTVALSATPTTSVIRSIPGADIELNRQSLLSRGFLLIAASISATPVVSRGAQEDIEEYSADSLISRREHWRLLSPSMSPIFPAKVIISK
QVTILNSSALHRFSTKAFNPSEYQAITEASSNQRLTNIKSQAADSLRELSQTCATCSMTEIKSSREFSDQVLHSKQSHFYETFWMNSAIL
ASWYALMGAQTITSGHSFSSATEITPSVAFTEVPSLFPSKKSAKRTILSSSLEESITLSSNLDVNLCLDKTCLSIVPSQTISSDLMNSDL
TSKMTTDELSVSENILKLLKIRQYGITMGPTEVLNQESLLDMEKSKGSHTLFKLHPSDSSLDFELNLQIYPDVTLKTYSEITHANDFKNN
LPPLTGSVPDFSEVTTNVAFYTVSATPALSIQTSSSMSVIRPDWPYFTDYMTSLKKEVKTSSEWSKWELQPSVQYQEFPTASRHLPFTRS
LTLSSLESILAPQRLMISDFSCVRYYGDSYLEFQNVALNPQNNISLEFQTFSSYGLLLYVKQDSNLVDGFFIQLFIENGTLKYHFYCPGE
AKFKSINTTVRVDNGQKYTLLIRQELDPCNAELTILGRNTQICESINHVLGKPLPKSGSVFIGGFPDLHGKIQMPVPVKNFTGCIEVIEI
NNWRSFIPSKAVKNYHINNCRSQGFMLSPTASFVDASDVTQGVDTMWTSVSPSVAAPSVCQQDVCHNGGTCHAIFLSSGIVSFQCDCPLH
FTGRFCEKDAGLFFPSFNGNSYLELPFLKFVLEKEHNRTVTIYLTIKTNSLNGTILYSNGNNCGKQFLHLFLVEGRPSVKYGCGNSQNIL
TVSANYSINTNAFTPITIRYTTPVGSPGVVCMIEMTADGKPPVQKKDTEISHASQAYFESMFLGHIPANVQIHKKAGPVYGFRGCILDLQ
VNNKEFFIIDEARHGKNIENCHVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFASCENNPCGNGATCVPKSGTDIVCLCPYGRS
GPLCTDAINITQPRFSGTDAFGYTSFLAYSRISDISFHYEFHLKFQLANNHSALQNNLIFFTGQKGHGLNGDDFLAVGLLNGSVVYSYNL
GSGIASIRSEPLNLSLGVHTVHLGKFFQEGWLKVDDHKNKSIIAPGRLVGLNVFSQFYVGGYSEYTPDLLPNGADFKNGFQGCIFTLQVR
TEKDGHFRGLGNPEGHPNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPH
GYTCFCPLGTTGIYCEQALILIVILEKPKPAERKVKKEALSISDPSFRSNELSWMSFASFHVRKKTHIQLQFQPLAADGILFYAAQHLKA
QSGDFLCISLVNSSVQLRYNLGDRTIILETLQKVTINGSTWHIIKAGRVGAEGYLDLDGINVTEKASTKMSSLDTNTDFYIGGVSSLNLV
NPMAIENEPVGFQGCIRQVIINNQELQLTEFGAKGGSNVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNLCL
HQSLCIPDQSFSYSCLCTLGWVGRYCENKTSFSTAKFMGNSYIKYIDPNYRMRNLQFTTISLNFSTTKTEGLIVWMGIAQNEENDFLAIG
LHNQTLKIAVNLGERISVPMSYNNGTFCCNKWHHVVVIQNQTLIKAYINNSLILSEDIDPHKNFVALNYDGICYLGGFEYGRKVNIVTQE

--------------------------------------------------------------

>34786_34786_6_GRIK2-EYS_GRIK2_chr6_101847268_ENST00000358361_EYS_chr6_65767620_ENST00000503581_length(amino acids)=2541AA_BP=71
MRSPLDASSFLPEPRSRTLDRGSGCRACGHRNTMKIIFPILSNPVFRRTVKLLLCLLWIGYSQGTTHVLRFGTQCEIDIDECASHPCKNG
ATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMNPCKNN
STCTDLYKSYRCECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDAN
QHCICREEFEGKNCEIDVKDCLFLSCQDYGDCEDMVNNFRCICRPGFSGSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFC
ELDVNKCKISPCLDEENCVYRTDGYNCLCAPGYTGINCEINLDECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETNANDCLSNPCLH
GRCTELINEYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTCICPRGYTGAYCEKSIDNCAEPELNSVICLNGGICVDGPGH
TFDCRCLPGFSGQFCEININECSSSPCLHGADCEDHINGYVCKCQPGWSGHHCENELECIPNSCVHELCMENEPGSTCLCTPGFMTCSIG
LLCGDEIRRITCLTPIFQRTDPISTQTYTIPPSETLVSSFPSIKATRIPAIMDTYPVDQGPKQTGIVKHDILPTTGLATLRISTPLESYL
LQELIVTRELSAKHSLLSSADVSSSRFLNFGIRDPAQIVQDKTSVSHMPIRTSAATLGFFFPDRRARTPFIMSSLMSDFIFPTQSLLFEN
CQTVALSATPTTSVIRSIPGADIELNRQSLLSRGFLLIAASISATPVVSRGAQEDIEEYSADSLISRREHWRLLSPSMSPIFPAKVIISK
QVTILNSSALHRFSTKAFNPSEYQAITEASSNQRLTNIKSQAADSLRELSQTCATCSMTEIKSSREFSDQVLHSKQSHFYETFWMNSAIL
ASWYALMGAQTITSGHSFSSATEITPSVAFTEVPSLFPSKKSAKRTILSSSLEESITLSSNLDVNLCLDKTCLSIVPSQTISSDLMNSDL
TSKMTTDELSVSENILKLLKIRQYGITMGPTEVLNQESLLDMEKSKGSHTLFKLHPSDSSLDFELNLQIYPDVTLKTYSEITHANDFKNN
LPPLTGSVPDFSEVTTNVAFYTVSATPALSIQTSSSMSVIRPDWPYFTDYMTSLKKEVKTSSEWSKWELQPSVQYQEFPTASRHLPFTRS
LTLSSLESILAPQRLMISDFSCVRYYGDSYLEFQNVALNPQNNISLEFQTFSSYGLLLYVKQDSNLVDGFFIQLFIENGTLKYHFYCPGE
AKFKSINTTVRVDNGQKYTLLIRQELDPCNAELTILGRNTQICESINHVLGKPLPKSGSVFIGGFPDLHGKIQMPVPVKNFTGCIEVIEI
NNWRSFIPSKAVKNYHINNCRSQGFMLSPTASFVDASDVTQGVDTMWTSVSPSVAAPSVCQQDVCHNGGTCHAIFLSSGIVSFQCDCPLH
FTGRFCEKDAGLFFPSFNGNSYLELPFLKFVLEKEHNRTVTIYLTIKTNSLNGTILYSNGNNCGKQFLHLFLVEGRPSVKYGCGNSQNIL
TVSANYSINTNAFTPITIRYTTPVGSPGVVCMIEMTADGKPPVQKKDTEISHASQAYFESMFLGHIPANVQIHKKAGPVYGFRGCILDLQ
VNNKEFFIIDEARHGKNIENCHVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFASCENNPCGNGATCVPKSGTDIVCLCPYGRS
GPLCTDAINITQPRFSGTDAFGYTSFLAYSRISDISFHYEFHLKFQLANNHSALQNNLIFFTGQKGHGLNGDDFLAVGLLNGSVVYSYNL
GSGIASIRSEPLNLSLGVHTVHLGKFFQEGWLKVDDHKNKSIIAPGRLVGLNVFSQFYVGGYSEYTPDLLPNGADFKNGFQGCIFTLQVR
TEKDGHFRGLGNPEGHPNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPH
GYTCFCPLGTTGIYCEQALSISDPSFRSNELSWMSFASFHVRKKTHIQLQFQPLAADGILFYAAQHLKAQSGDFLCISLVNSSVQLRYNL
GDRTIILETLQKVTINGSTWHIIKAGRVGAEGYLDLDGINVTEKASTKMSSLDTNTDFYIGGVSSLNLVNPMAIENEPVGFQGCIRQVII
NNQELQLTEFGAKGGSNVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNLCLHQSLCIPDQSFSYSCLCTLGW
VGRYCENKTSFSTAKFMGNSYIKYIDPNYRMRNLQFTTISLNFSTTKTEGLIVWMGIAQNEENDFLAIGLHNQTLKIAVNLGERISVPMS
YNNGTFCCNKWHHVVVIQNQTLIKAYINNSLILSEDIDPHKNFVALNYDGICYLGGFEYGRKVNIVTQEIFKTNFVGKIKDVVFFQEPKN

--------------------------------------------------------------

>34786_34786_7_GRIK2-EYS_GRIK2_chr6_101847268_ENST00000369137_EYS_chr6_65767620_ENST00000370616_length(amino acids)=2529AA_BP=38
MKIIFPILSNPVFRRTVKLLLCLLWIGYSQGTTHVLRFGTQCEIDIDECASHPCKNGATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYV
GIRCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEINECDSD
PCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDCLFLSCQDYGDCE
DMVNNFRCICRPGFSGSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCELDVNKCKISPCLDEENCVYRTDGYNCLCAPGY
TGINCEINLDECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETNANDCLSNPCLHGRCTELINEYPCSCDADGTSTQCKIKINDCTSI
PCMNEGFCQKSAHGFTCICPRGYTGAYCEKSIDNCAEPELNSVICLNGGICVDGPGHTFDCRCLPGFSGQFCEININECSSSPCLHGADC
EDHINGYVCKCQPGWSGHHCENELECIPNSCVHELCMENEPGSTCLCTPGFMTCSIGLLCGDEIRRITCLTPIFQRTDPISTQTYTIPPS
ETLVSSFPSIKATRIPAIMDTYPVDQGPKQTGIVKHDILPTTGLATLRISTPLESYLLQELIVTRELSAKHSLLSSADVSSSRFLNFGIR
DPAQIVQDKTSVSHMPIRTSAATLGFFFPDRRARTPFIMSSLMSDFIFPTQSLLFENCQTVALSATPTTSVIRSIPGADIELNRQSLLSR
GFLLIAASISATPVVSRGAQEDIEEYSADSLISRREHWRLLSPSMSPIFPAKVIISKQVTILNSSALHRFSTKAFNPSEYQAITEASSNQ
RLTNIKSQAADSLRELSQTCATCSMTEIKSSREFSDQVLHSKQSHFYETFWMNSAILASWYALMGAQTITSGHSFSSATEITPSVAFTEV
PSLFPSKKSAKRTILSSSLEESITLSSNLDVNLCLDKTCLSIVPSQTISSDLMNSDLTSKMTTDELSVSENILKLLKIRQYGITMGPTEV
LNQESLLDMEKSKGSHTLFKLHPSDSSLDFELNLQIYPDVTLKTYSEITHANDFKNNLPPLTGSVPDFSEVTTNVAFYTVSATPALSIQT
SSSMSVIRPDWPYFTDYMTSLKKEVKTSSEWSKWELQPSVQYQEFPTASRHLPFTRSLTLSSLESILAPQRLMISDFSCVRYYGDSYLEF
QNVALNPQNNISLEFQTFSSYGLLLYVKQDSNLVDGFFIQLFIENGTLKYHFYCPGEAKFKSINTTVRVDNGQKYTLLIRQELDPCNAEL
TILGRNTQICESINHVLGKPLPKSGSVFIGGFPDLHGKIQMPVPVKNFTGCIEVIEINNWRSFIPSKAVKNYHINNCRSQGFMLSPTASF
VDASDVTQGVDTMWTSVSPSVAAPSVCQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKDAGLFFPSFNGNSYLELPFLKFVLE
KEHNRTVTIYLTIKTNSLNGTILYSNGNNCGKQFLHLFLVEGRPSVKYGCGNSQNILTVSANYSINTNAFTPITIRYTTPVGSPGVVCMI
EMTADGKPPVQKKDTEISHASQAYFESMFLGHIPANVQIHKKAGPVYGFRGCILDLQVNNKEFFIIDEARHGKNIENCHVPWCAHHLCRN
NGTCISDNENLFCECPRLYSGKLCQFASCENNPCGNGATCVPKSGTDIVCLCPYGRSGPLCTDAINITQPRFSGTDAFGYTSFLAYSRIS
DISFHYEFHLKFQLANNHSALQNNLIFFTGQKGHGLNGDDFLAVGLLNGSVVYSYNLGSGIASIRSEPLNLSLGVHTVHLGKFFQEGWLK
VDDHKNKSIIAPGRLVGLNVFSQFYVGGYSEYTPDLLPNGADFKNGFQGCIFTLQVRTEKDGHFRGLGNPEGHPNAGRSVGQCHASPCSL
MKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPHGYTCFCPLGTTGIYCEQALILIVILEKPKPAER
KVKKEALSISDPSFRSNELSWMSFASFHVRKKTHIQLQFQPLAADGILFYAAQHLKAQSGDFLCISLVNSSVQLRYNLGDRTIILETLQK
VTINGSTWHIIKAGRVGAEGYLDLDGINVTEKASTKMSSLDTNTDFYIGGVSSLNLVNPMAIENEPVGFQGCIRQVIINNQELQLTEFGA
KGGSNVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNLCLHQSLCIPDQSFSYSCLCTLGWVGRYCENKTSFS
TAKFMGNSYIKYIDPNYRMRNLQFTTISLNFSTTKTEGLIVWMGIAQNEENDFLAIGLHNQTLKIAVNLGERISVPMSYNNGTFCCNKWH
HVVVIQNQTLIKAYINNSLILSEDIDPHKNFVALNYDGICYLGGFEYGRKVNIVTQEIFKTNFVGKIKDVVFFQEPKNIELIKLEGYNVY

--------------------------------------------------------------

>34786_34786_8_GRIK2-EYS_GRIK2_chr6_101847268_ENST00000369137_EYS_chr6_65767620_ENST00000370621_length(amino acids)=2529AA_BP=38
MKIIFPILSNPVFRRTVKLLLCLLWIGYSQGTTHVLRFGTQCEIDIDECASHPCKNGATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYV
GIRCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEINECDSD
PCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDCLFLSCQDYGDCE
DMVNNFRCICRPGFSGSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCELDVNKCKISPCLDEENCVYRTDGYNCLCAPGY
TGINCEINLDECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETNANDCLSNPCLHGRCTELINEYPCSCDADGTSTQCKIKINDCTSI
PCMNEGFCQKSAHGFTCICPRGYTGAYCEKSIDNCAEPELNSVICLNGGICVDGPGHTFDCRCLPGFSGQFCEININECSSSPCLHGADC
EDHINGYVCKCQPGWSGHHCENELECIPNSCVHELCMENEPGSTCLCTPGFMTCSIGLLCGDEIRRITCLTPIFQRTDPISTQTYTIPPS
ETLVSSFPSIKATRIPAIMDTYPVDQGPKQTGIVKHDILPTTGLATLRISTPLESYLLQELIVTRELSAKHSLLSSADVSSSRFLNFGIR
DPAQIVQDKTSVSHMPIRTSAATLGFFFPDRRARTPFIMSSLMSDFIFPTQSLLFENCQTVALSATPTTSVIRSIPGADIELNRQSLLSR
GFLLIAASISATPVVSRGAQEDIEEYSADSLISRREHWRLLSPSMSPIFPAKVIISKQVTILNSSALHRFSTKAFNPSEYQAITEASSNQ
RLTNIKSQAADSLRELSQTCATCSMTEIKSSREFSDQVLHSKQSHFYETFWMNSAILASWYALMGAQTITSGHSFSSATEITPSVAFTEV
PSLFPSKKSAKRTILSSSLEESITLSSNLDVNLCLDKTCLSIVPSQTISSDLMNSDLTSKMTTDELSVSENILKLLKIRQYGITMGPTEV
LNQESLLDMEKSKGSHTLFKLHPSDSSLDFELNLQIYPDVTLKTYSEITHANDFKNNLPPLTGSVPDFSEVTTNVAFYTVSATPALSIQT
SSSMSVIRPDWPYFTDYMTSLKKEVKTSSEWSKWELQPSVQYQEFPTASRHLPFTRSLTLSSLESILAPQRLMISDFSCVRYYGDSYLEF
QNVALNPQNNISLEFQTFSSYGLLLYVKQDSNLVDGFFIQLFIENGTLKYHFYCPGEAKFKSINTTVRVDNGQKYTLLIRQELDPCNAEL
TILGRNTQICESINHVLGKPLPKSGSVFIGGFPDLHGKIQMPVPVKNFTGCIEVIEINNWRSFIPSKAVKNYHINNCRSQGFMLSPTASF
VDASDVTQGVDTMWTSVSPSVAAPSVCQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKDAGLFFPSFNGNSYLELPFLKFVLE
KEHNRTVTIYLTIKTNSLNGTILYSNGNNCGKQFLHLFLVEGRPSVKYGCGNSQNILTVSANYSINTNAFTPITIRYTTPVGSPGVVCMI
EMTADGKPPVQKKDTEISHASQAYFESMFLGHIPANVQIHKKAGPVYGFRGCILDLQVNNKEFFIIDEARHGKNIENCHVPWCAHHLCRN
NGTCISDNENLFCECPRLYSGKLCQFASCENNPCGNGATCVPKSGTDIVCLCPYGRSGPLCTDAINITQPRFSGTDAFGYTSFLAYSRIS
DISFHYEFHLKFQLANNHSALQNNLIFFTGQKGHGLNGDDFLAVGLLNGSVVYSYNLGSGIASIRSEPLNLSLGVHTVHLGKFFQEGWLK
VDDHKNKSIIAPGRLVGLNVFSQFYVGGYSEYTPDLLPNGADFKNGFQGCIFTLQVRTEKDGHFRGLGNPEGHPNAGRSVGQCHASPCSL
MKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPHGYTCFCPLGTTGIYCEQALILIVILEKPKPAER
KVKKEALSISDPSFRSNELSWMSFASFHVRKKTHIQLQFQPLAADGILFYAAQHLKAQSGDFLCISLVNSSVQLRYNLGDRTIILETLQK
VTINGSTWHIIKAGRVGAEGYLDLDGINVTEKASTKMSSLDTNTDFYIGGVSSLNLVNPMAIENEPVGFQGCIRQVIINNQELQLTEFGA
KGGSNVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNLCLHQSLCIPDQSFSYSCLCTLGWVGRYCENKTSFS
TAKFMGNSYIKYIDPNYRMRNLQFTTISLNFSTTKTEGLIVWMGIAQNEENDFLAIGLHNQTLKIAVNLGERISVPMSYNNGTFCCNKWH
HVVVIQNQTLIKAYINNSLILSEDIDPHKNFVALNYDGICYLGGFEYGRKVNIVTQEIFKTNFVGKIKDVVFFQEPKNIELIKLEGYNVY

--------------------------------------------------------------

>34786_34786_9_GRIK2-EYS_GRIK2_chr6_101847268_ENST00000369137_EYS_chr6_65767620_ENST00000503581_length(amino acids)=2508AA_BP=38
MKIIFPILSNPVFRRTVKLLLCLLWIGYSQGTTHVLRFGTQCEIDIDECASHPCKNGATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYV
GIRCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEINECDSD
PCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDCLFLSCQDYGDCE
DMVNNFRCICRPGFSGSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCELDVNKCKISPCLDEENCVYRTDGYNCLCAPGY
TGINCEINLDECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETNANDCLSNPCLHGRCTELINEYPCSCDADGTSTQCKIKINDCTSI
PCMNEGFCQKSAHGFTCICPRGYTGAYCEKSIDNCAEPELNSVICLNGGICVDGPGHTFDCRCLPGFSGQFCEININECSSSPCLHGADC
EDHINGYVCKCQPGWSGHHCENELECIPNSCVHELCMENEPGSTCLCTPGFMTCSIGLLCGDEIRRITCLTPIFQRTDPISTQTYTIPPS
ETLVSSFPSIKATRIPAIMDTYPVDQGPKQTGIVKHDILPTTGLATLRISTPLESYLLQELIVTRELSAKHSLLSSADVSSSRFLNFGIR
DPAQIVQDKTSVSHMPIRTSAATLGFFFPDRRARTPFIMSSLMSDFIFPTQSLLFENCQTVALSATPTTSVIRSIPGADIELNRQSLLSR
GFLLIAASISATPVVSRGAQEDIEEYSADSLISRREHWRLLSPSMSPIFPAKVIISKQVTILNSSALHRFSTKAFNPSEYQAITEASSNQ
RLTNIKSQAADSLRELSQTCATCSMTEIKSSREFSDQVLHSKQSHFYETFWMNSAILASWYALMGAQTITSGHSFSSATEITPSVAFTEV
PSLFPSKKSAKRTILSSSLEESITLSSNLDVNLCLDKTCLSIVPSQTISSDLMNSDLTSKMTTDELSVSENILKLLKIRQYGITMGPTEV
LNQESLLDMEKSKGSHTLFKLHPSDSSLDFELNLQIYPDVTLKTYSEITHANDFKNNLPPLTGSVPDFSEVTTNVAFYTVSATPALSIQT
SSSMSVIRPDWPYFTDYMTSLKKEVKTSSEWSKWELQPSVQYQEFPTASRHLPFTRSLTLSSLESILAPQRLMISDFSCVRYYGDSYLEF
QNVALNPQNNISLEFQTFSSYGLLLYVKQDSNLVDGFFIQLFIENGTLKYHFYCPGEAKFKSINTTVRVDNGQKYTLLIRQELDPCNAEL
TILGRNTQICESINHVLGKPLPKSGSVFIGGFPDLHGKIQMPVPVKNFTGCIEVIEINNWRSFIPSKAVKNYHINNCRSQGFMLSPTASF
VDASDVTQGVDTMWTSVSPSVAAPSVCQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKDAGLFFPSFNGNSYLELPFLKFVLE
KEHNRTVTIYLTIKTNSLNGTILYSNGNNCGKQFLHLFLVEGRPSVKYGCGNSQNILTVSANYSINTNAFTPITIRYTTPVGSPGVVCMI
EMTADGKPPVQKKDTEISHASQAYFESMFLGHIPANVQIHKKAGPVYGFRGCILDLQVNNKEFFIIDEARHGKNIENCHVPWCAHHLCRN
NGTCISDNENLFCECPRLYSGKLCQFASCENNPCGNGATCVPKSGTDIVCLCPYGRSGPLCTDAINITQPRFSGTDAFGYTSFLAYSRIS
DISFHYEFHLKFQLANNHSALQNNLIFFTGQKGHGLNGDDFLAVGLLNGSVVYSYNLGSGIASIRSEPLNLSLGVHTVHLGKFFQEGWLK
VDDHKNKSIIAPGRLVGLNVFSQFYVGGYSEYTPDLLPNGADFKNGFQGCIFTLQVRTEKDGHFRGLGNPEGHPNAGRSVGQCHASPCSL
MKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPHGYTCFCPLGTTGIYCEQALSISDPSFRSNELSW
MSFASFHVRKKTHIQLQFQPLAADGILFYAAQHLKAQSGDFLCISLVNSSVQLRYNLGDRTIILETLQKVTINGSTWHIIKAGRVGAEGY
LDLDGINVTEKASTKMSSLDTNTDFYIGGVSSLNLVNPMAIENEPVGFQGCIRQVIINNQELQLTEFGAKGGSNVGDCDGTACGYNTCRN
GGECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNLCLHQSLCIPDQSFSYSCLCTLGWVGRYCENKTSFSTAKFMGNSYIKYIDPNYRMRN
LQFTTISLNFSTTKTEGLIVWMGIAQNEENDFLAIGLHNQTLKIAVNLGERISVPMSYNNGTFCCNKWHHVVVIQNQTLIKAYINNSLIL

--------------------------------------------------------------

>34786_34786_10_GRIK2-EYS_GRIK2_chr6_101847268_ENST00000369138_EYS_chr6_65767620_ENST00000370616_length(amino acids)=2563AA_BP=71
MRSPLDASSFLPEPRSRTLDRGSGCRACGHRNTMKIIFPILSNPVFRRTVKLLLCLLWIGYSQGTTHVLRFGTQCEIDIDECASHPCKNG
ATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMNPCKNN
STCTDLYKSYRCECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDAN
QHCICREEFEGKNCEIDVKDCLFLSCQDYGDCEDMVNNFRCICRPGFSGSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFC
ELDVNKCKISPCLDEENCVYRTDGYNCLCAPGYTGINCEINLDECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETNANDCLSNPCLH
GRCTELINEYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTCICPRGYTGAYCEKSIDNCAEPELNSVICLNGGICVDGPGH
TFDCRCLPGFSGQFCEININECSSSPCLHGADCEDHINGYVCKCQPGWSGHHCENELECIPNSCVHELCMENEPGSTCLCTPGFMTCSIG
LLCGDEIRRITCLTPIFQRTDPISTQTYTIPPSETLVSSFPSIKATRIPAIMDTYPVDQGPKQTGIVKHDILPTTGLATLRISTPLESYL
LQELIVTRELSAKHSLLSSADVSSSRFLNFGIRDPAQIVQDKTSVSHMPIRTSAATLGFFFPDRRARTPFIMSSLMSDFIFPTQSLLFEN
CQTVALSATPTTSVIRSIPGADIELNRQSLLSRGFLLIAASISATPVVSRGAQEDIEEYSADSLISRREHWRLLSPSMSPIFPAKVIISK
QVTILNSSALHRFSTKAFNPSEYQAITEASSNQRLTNIKSQAADSLRELSQTCATCSMTEIKSSREFSDQVLHSKQSHFYETFWMNSAIL
ASWYALMGAQTITSGHSFSSATEITPSVAFTEVPSLFPSKKSAKRTILSSSLEESITLSSNLDVNLCLDKTCLSIVPSQTISSDLMNSDL
TSKMTTDELSVSENILKLLKIRQYGITMGPTEVLNQESLLDMEKSKGSHTLFKLHPSDSSLDFELNLQIYPDVTLKTYSEITHANDFKNN
LPPLTGSVPDFSEVTTNVAFYTVSATPALSIQTSSSMSVIRPDWPYFTDYMTSLKKEVKTSSEWSKWELQPSVQYQEFPTASRHLPFTRS
LTLSSLESILAPQRLMISDFSCVRYYGDSYLEFQNVALNPQNNISLEFQTFSSYGLLLYVKQDSNLVDGFFIQLFIENGTLKYHFYCPGE
AKFKSINTTVRVDNGQKYTLLIRQELDPCNAELTILGRNTQICESINHVLGKPLPKSGSVFIGGFPDLHGKIQMPVPVKNFTGCIEVIEI
NNWRSFIPSKAVKNYHINNCRSQGFMLSPTASFVDASDVTQGVDTMWTSVSPSVAAPSVCQQDVCHNGGTCHAIFLSSGIVSFQCDCPLH
FTGRFCEKDAGLFFPSFNGNSYLELPFLKFVLEKEHNRTVTIYLTIKTNSLNGTILYSNGNNCGKQFLHLFLVEGRPSVKYGCGNSQNIL
TVSANYSINTNAFTPITIRYTTPVGSPGVVCMIEMTADGKPPVQKKDTEISHASQAYFESMFLGHIPANVQIHKKAGPVYGFRGCILDLQ
VNNKEFFIIDEARHGKNIENCHVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFASCENNPCGNGATCVPKSGTDIVCLCPYGRS
GPLCTDAINITQPRFSGTDAFGYTSFLAYSRISDISFHYEFHLKFQLANNHSALQNNLIFFTGQKGHGLNGDDFLAVGLLNGSVVYSYNL
GSGIASIRSEPLNLSLGVHTVHLGKFFQEGWLKVDDHKNKSIIAPGRLVGLNVFSQFYVGGYSEYTPDLLPNGADFKNGFQGCIFTLQVR
TEKDGHFRGLGNPEGHPNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPH
GYTCFCPLGTTGIYCEQALILIVILEKPKPAERKVKKEALSISDPSFRSNELSWMSFASFHVRKKTHIQLQFQPLAADGILFYAAQHLKA
QSGDFLCISLVNSSVQLRYNLGDRTIILETLQKVTINGSTWHIIKAGRVGAEGYLDLDGINVTEKASTKMSSLDTNTDFYIGGVSSLNLV
NPMAIENEPVGFQGCIRQVIINNQELQLTEFGAKGGSNVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNLCL
HQSLCIPDQSFSYSCLCTLGWVGRYCENKTSFSTAKFMGNSYIKYIDPNYRMRNLQFTTISLNFSTTKTEGLIVWMGIAQNEENDFLAIG
LHNQTLKIAVNLGERISVPMSYNNGTFCCNKWHHVVVIQNQTLIKAYINNSLILSEDIDPHKNFVALNYDGICYLGGFEYGRKVNIVTQE

--------------------------------------------------------------

>34786_34786_11_GRIK2-EYS_GRIK2_chr6_101847268_ENST00000369138_EYS_chr6_65767620_ENST00000370621_length(amino acids)=2562AA_BP=71
MRSPLDASSFLPEPRSRTLDRGSGCRACGHRNTMKIIFPILSNPVFRRTVKLLLCLLWIGYSQGTTHVLRFGTQCEIDIDECASHPCKNG
ATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMNPCKNN
STCTDLYKSYRCECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDAN
QHCICREEFEGKNCEIDVKDCLFLSCQDYGDCEDMVNNFRCICRPGFSGSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFC
ELDVNKCKISPCLDEENCVYRTDGYNCLCAPGYTGINCEINLDECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETNANDCLSNPCLH
GRCTELINEYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTCICPRGYTGAYCEKSIDNCAEPELNSVICLNGGICVDGPGH
TFDCRCLPGFSGQFCEININECSSSPCLHGADCEDHINGYVCKCQPGWSGHHCENELECIPNSCVHELCMENEPGSTCLCTPGFMTCSIG
LLCGDEIRRITCLTPIFQRTDPISTQTYTIPPSETLVSSFPSIKATRIPAIMDTYPVDQGPKQTGIVKHDILPTTGLATLRISTPLESYL
LQELIVTRELSAKHSLLSSADVSSSRFLNFGIRDPAQIVQDKTSVSHMPIRTSAATLGFFFPDRRARTPFIMSSLMSDFIFPTQSLLFEN
CQTVALSATPTTSVIRSIPGADIELNRQSLLSRGFLLIAASISATPVVSRGAQEDIEEYSADSLISRREHWRLLSPSMSPIFPAKVIISK
QVTILNSSALHRFSTKAFNPSEYQAITEASSNQRLTNIKSQAADSLRELSQTCATCSMTEIKSSREFSDQVLHSKQSHFYETFWMNSAIL
ASWYALMGAQTITSGHSFSSATEITPSVAFTEVPSLFPSKKSAKRTILSSSLEESITLSSNLDVNLCLDKTCLSIVPSQTISSDLMNSDL
TSKMTTDELSVSENILKLLKIRQYGITMGPTEVLNQESLLDMEKSKGSHTLFKLHPSDSSLDFELNLQIYPDVTLKTYSEITHANDFKNN
LPPLTGSVPDFSEVTTNVAFYTVSATPALSIQTSSSMSVIRPDWPYFTDYMTSLKKEVKTSSEWSKWELQPSVQYQEFPTASRHLPFTRS
LTLSSLESILAPQRLMISDFSCVRYYGDSYLEFQNVALNPQNNISLEFQTFSSYGLLLYVKQDSNLVDGFFIQLFIENGTLKYHFYCPGE
AKFKSINTTVRVDNGQKYTLLIRQELDPCNAELTILGRNTQICESINHVLGKPLPKSGSVFIGGFPDLHGKIQMPVPVKNFTGCIEVIEI
NNWRSFIPSKAVKNYHINNCRSQGFMLSPTASFVDASDVTQGVDTMWTSVSPSVAAPSVCQQDVCHNGGTCHAIFLSSGIVSFQCDCPLH
FTGRFCEKDAGLFFPSFNGNSYLELPFLKFVLEKEHNRTVTIYLTIKTNSLNGTILYSNGNNCGKQFLHLFLVEGRPSVKYGCGNSQNIL
TVSANYSINTNAFTPITIRYTTPVGSPGVVCMIEMTADGKPPVQKKDTEISHASQAYFESMFLGHIPANVQIHKKAGPVYGFRGCILDLQ
VNNKEFFIIDEARHGKNIENCHVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFASCENNPCGNGATCVPKSGTDIVCLCPYGRS
GPLCTDAINITQPRFSGTDAFGYTSFLAYSRISDISFHYEFHLKFQLANNHSALQNNLIFFTGQKGHGLNGDDFLAVGLLNGSVVYSYNL
GSGIASIRSEPLNLSLGVHTVHLGKFFQEGWLKVDDHKNKSIIAPGRLVGLNVFSQFYVGGYSEYTPDLLPNGADFKNGFQGCIFTLQVR
TEKDGHFRGLGNPEGHPNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPH
GYTCFCPLGTTGIYCEQALILIVILEKPKPAERKVKKEALSISDPSFRSNELSWMSFASFHVRKKTHIQLQFQPLAADGILFYAAQHLKA
QSGDFLCISLVNSSVQLRYNLGDRTIILETLQKVTINGSTWHIIKAGRVGAEGYLDLDGINVTEKASTKMSSLDTNTDFYIGGVSSLNLV
NPMAIENEPVGFQGCIRQVIINNQELQLTEFGAKGGSNVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNLCL
HQSLCIPDQSFSYSCLCTLGWVGRYCENKTSFSTAKFMGNSYIKYIDPNYRMRNLQFTTISLNFSTTKTEGLIVWMGIAQNEENDFLAIG
LHNQTLKIAVNLGERISVPMSYNNGTFCCNKWHHVVVIQNQTLIKAYINNSLILSEDIDPHKNFVALNYDGICYLGGFEYGRKVNIVTQE

--------------------------------------------------------------

>34786_34786_12_GRIK2-EYS_GRIK2_chr6_101847268_ENST00000369138_EYS_chr6_65767620_ENST00000503581_length(amino acids)=2541AA_BP=71
MRSPLDASSFLPEPRSRTLDRGSGCRACGHRNTMKIIFPILSNPVFRRTVKLLLCLLWIGYSQGTTHVLRFGTQCEIDIDECASHPCKNG
ATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMNPCKNN
STCTDLYKSYRCECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDAN
QHCICREEFEGKNCEIDVKDCLFLSCQDYGDCEDMVNNFRCICRPGFSGSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFC
ELDVNKCKISPCLDEENCVYRTDGYNCLCAPGYTGINCEINLDECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETNANDCLSNPCLH
GRCTELINEYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTCICPRGYTGAYCEKSIDNCAEPELNSVICLNGGICVDGPGH
TFDCRCLPGFSGQFCEININECSSSPCLHGADCEDHINGYVCKCQPGWSGHHCENELECIPNSCVHELCMENEPGSTCLCTPGFMTCSIG
LLCGDEIRRITCLTPIFQRTDPISTQTYTIPPSETLVSSFPSIKATRIPAIMDTYPVDQGPKQTGIVKHDILPTTGLATLRISTPLESYL
LQELIVTRELSAKHSLLSSADVSSSRFLNFGIRDPAQIVQDKTSVSHMPIRTSAATLGFFFPDRRARTPFIMSSLMSDFIFPTQSLLFEN
CQTVALSATPTTSVIRSIPGADIELNRQSLLSRGFLLIAASISATPVVSRGAQEDIEEYSADSLISRREHWRLLSPSMSPIFPAKVIISK
QVTILNSSALHRFSTKAFNPSEYQAITEASSNQRLTNIKSQAADSLRELSQTCATCSMTEIKSSREFSDQVLHSKQSHFYETFWMNSAIL
ASWYALMGAQTITSGHSFSSATEITPSVAFTEVPSLFPSKKSAKRTILSSSLEESITLSSNLDVNLCLDKTCLSIVPSQTISSDLMNSDL
TSKMTTDELSVSENILKLLKIRQYGITMGPTEVLNQESLLDMEKSKGSHTLFKLHPSDSSLDFELNLQIYPDVTLKTYSEITHANDFKNN
LPPLTGSVPDFSEVTTNVAFYTVSATPALSIQTSSSMSVIRPDWPYFTDYMTSLKKEVKTSSEWSKWELQPSVQYQEFPTASRHLPFTRS
LTLSSLESILAPQRLMISDFSCVRYYGDSYLEFQNVALNPQNNISLEFQTFSSYGLLLYVKQDSNLVDGFFIQLFIENGTLKYHFYCPGE
AKFKSINTTVRVDNGQKYTLLIRQELDPCNAELTILGRNTQICESINHVLGKPLPKSGSVFIGGFPDLHGKIQMPVPVKNFTGCIEVIEI
NNWRSFIPSKAVKNYHINNCRSQGFMLSPTASFVDASDVTQGVDTMWTSVSPSVAAPSVCQQDVCHNGGTCHAIFLSSGIVSFQCDCPLH
FTGRFCEKDAGLFFPSFNGNSYLELPFLKFVLEKEHNRTVTIYLTIKTNSLNGTILYSNGNNCGKQFLHLFLVEGRPSVKYGCGNSQNIL
TVSANYSINTNAFTPITIRYTTPVGSPGVVCMIEMTADGKPPVQKKDTEISHASQAYFESMFLGHIPANVQIHKKAGPVYGFRGCILDLQ
VNNKEFFIIDEARHGKNIENCHVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFASCENNPCGNGATCVPKSGTDIVCLCPYGRS
GPLCTDAINITQPRFSGTDAFGYTSFLAYSRISDISFHYEFHLKFQLANNHSALQNNLIFFTGQKGHGLNGDDFLAVGLLNGSVVYSYNL
GSGIASIRSEPLNLSLGVHTVHLGKFFQEGWLKVDDHKNKSIIAPGRLVGLNVFSQFYVGGYSEYTPDLLPNGADFKNGFQGCIFTLQVR
TEKDGHFRGLGNPEGHPNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPH
GYTCFCPLGTTGIYCEQALSISDPSFRSNELSWMSFASFHVRKKTHIQLQFQPLAADGILFYAAQHLKAQSGDFLCISLVNSSVQLRYNL
GDRTIILETLQKVTINGSTWHIIKAGRVGAEGYLDLDGINVTEKASTKMSSLDTNTDFYIGGVSSLNLVNPMAIENEPVGFQGCIRQVII
NNQELQLTEFGAKGGSNVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNLCLHQSLCIPDQSFSYSCLCTLGW
VGRYCENKTSFSTAKFMGNSYIKYIDPNYRMRNLQFTTISLNFSTTKTEGLIVWMGIAQNEENDFLAIGLHNQTLKIAVNLGERISVPMS
YNNGTFCCNKWHHVVVIQNQTLIKAYINNSLILSEDIDPHKNFVALNYDGICYLGGFEYGRKVNIVTQEIFKTNFVGKIKDVVFFQEPKN

--------------------------------------------------------------

>34786_34786_13_GRIK2-EYS_GRIK2_chr6_101847268_ENST00000413795_EYS_chr6_65767620_ENST00000370616_length(amino acids)=2563AA_BP=71
MRSPLDASSFLPEPRSRTLDRGSGCRACGHRNTMKIIFPILSNPVFRRTVKLLLCLLWIGYSQGTTHVLRFGTQCEIDIDECASHPCKNG
ATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMNPCKNN
STCTDLYKSYRCECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDAN
QHCICREEFEGKNCEIDVKDCLFLSCQDYGDCEDMVNNFRCICRPGFSGSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFC
ELDVNKCKISPCLDEENCVYRTDGYNCLCAPGYTGINCEINLDECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETNANDCLSNPCLH
GRCTELINEYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTCICPRGYTGAYCEKSIDNCAEPELNSVICLNGGICVDGPGH
TFDCRCLPGFSGQFCEININECSSSPCLHGADCEDHINGYVCKCQPGWSGHHCENELECIPNSCVHELCMENEPGSTCLCTPGFMTCSIG
LLCGDEIRRITCLTPIFQRTDPISTQTYTIPPSETLVSSFPSIKATRIPAIMDTYPVDQGPKQTGIVKHDILPTTGLATLRISTPLESYL
LQELIVTRELSAKHSLLSSADVSSSRFLNFGIRDPAQIVQDKTSVSHMPIRTSAATLGFFFPDRRARTPFIMSSLMSDFIFPTQSLLFEN
CQTVALSATPTTSVIRSIPGADIELNRQSLLSRGFLLIAASISATPVVSRGAQEDIEEYSADSLISRREHWRLLSPSMSPIFPAKVIISK
QVTILNSSALHRFSTKAFNPSEYQAITEASSNQRLTNIKSQAADSLRELSQTCATCSMTEIKSSREFSDQVLHSKQSHFYETFWMNSAIL
ASWYALMGAQTITSGHSFSSATEITPSVAFTEVPSLFPSKKSAKRTILSSSLEESITLSSNLDVNLCLDKTCLSIVPSQTISSDLMNSDL
TSKMTTDELSVSENILKLLKIRQYGITMGPTEVLNQESLLDMEKSKGSHTLFKLHPSDSSLDFELNLQIYPDVTLKTYSEITHANDFKNN
LPPLTGSVPDFSEVTTNVAFYTVSATPALSIQTSSSMSVIRPDWPYFTDYMTSLKKEVKTSSEWSKWELQPSVQYQEFPTASRHLPFTRS
LTLSSLESILAPQRLMISDFSCVRYYGDSYLEFQNVALNPQNNISLEFQTFSSYGLLLYVKQDSNLVDGFFIQLFIENGTLKYHFYCPGE
AKFKSINTTVRVDNGQKYTLLIRQELDPCNAELTILGRNTQICESINHVLGKPLPKSGSVFIGGFPDLHGKIQMPVPVKNFTGCIEVIEI
NNWRSFIPSKAVKNYHINNCRSQGFMLSPTASFVDASDVTQGVDTMWTSVSPSVAAPSVCQQDVCHNGGTCHAIFLSSGIVSFQCDCPLH
FTGRFCEKDAGLFFPSFNGNSYLELPFLKFVLEKEHNRTVTIYLTIKTNSLNGTILYSNGNNCGKQFLHLFLVEGRPSVKYGCGNSQNIL
TVSANYSINTNAFTPITIRYTTPVGSPGVVCMIEMTADGKPPVQKKDTEISHASQAYFESMFLGHIPANVQIHKKAGPVYGFRGCILDLQ
VNNKEFFIIDEARHGKNIENCHVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFASCENNPCGNGATCVPKSGTDIVCLCPYGRS
GPLCTDAINITQPRFSGTDAFGYTSFLAYSRISDISFHYEFHLKFQLANNHSALQNNLIFFTGQKGHGLNGDDFLAVGLLNGSVVYSYNL
GSGIASIRSEPLNLSLGVHTVHLGKFFQEGWLKVDDHKNKSIIAPGRLVGLNVFSQFYVGGYSEYTPDLLPNGADFKNGFQGCIFTLQVR
TEKDGHFRGLGNPEGHPNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPH
GYTCFCPLGTTGIYCEQALILIVILEKPKPAERKVKKEALSISDPSFRSNELSWMSFASFHVRKKTHIQLQFQPLAADGILFYAAQHLKA
QSGDFLCISLVNSSVQLRYNLGDRTIILETLQKVTINGSTWHIIKAGRVGAEGYLDLDGINVTEKASTKMSSLDTNTDFYIGGVSSLNLV
NPMAIENEPVGFQGCIRQVIINNQELQLTEFGAKGGSNVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNLCL
HQSLCIPDQSFSYSCLCTLGWVGRYCENKTSFSTAKFMGNSYIKYIDPNYRMRNLQFTTISLNFSTTKTEGLIVWMGIAQNEENDFLAIG
LHNQTLKIAVNLGERISVPMSYNNGTFCCNKWHHVVVIQNQTLIKAYINNSLILSEDIDPHKNFVALNYDGICYLGGFEYGRKVNIVTQE

--------------------------------------------------------------

>34786_34786_14_GRIK2-EYS_GRIK2_chr6_101847268_ENST00000413795_EYS_chr6_65767620_ENST00000370621_length(amino acids)=2562AA_BP=71
MRSPLDASSFLPEPRSRTLDRGSGCRACGHRNTMKIIFPILSNPVFRRTVKLLLCLLWIGYSQGTTHVLRFGTQCEIDIDECASHPCKNG
ATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMNPCKNN
STCTDLYKSYRCECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDAN
QHCICREEFEGKNCEIDVKDCLFLSCQDYGDCEDMVNNFRCICRPGFSGSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFC
ELDVNKCKISPCLDEENCVYRTDGYNCLCAPGYTGINCEINLDECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETNANDCLSNPCLH
GRCTELINEYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTCICPRGYTGAYCEKSIDNCAEPELNSVICLNGGICVDGPGH
TFDCRCLPGFSGQFCEININECSSSPCLHGADCEDHINGYVCKCQPGWSGHHCENELECIPNSCVHELCMENEPGSTCLCTPGFMTCSIG
LLCGDEIRRITCLTPIFQRTDPISTQTYTIPPSETLVSSFPSIKATRIPAIMDTYPVDQGPKQTGIVKHDILPTTGLATLRISTPLESYL
LQELIVTRELSAKHSLLSSADVSSSRFLNFGIRDPAQIVQDKTSVSHMPIRTSAATLGFFFPDRRARTPFIMSSLMSDFIFPTQSLLFEN
CQTVALSATPTTSVIRSIPGADIELNRQSLLSRGFLLIAASISATPVVSRGAQEDIEEYSADSLISRREHWRLLSPSMSPIFPAKVIISK
QVTILNSSALHRFSTKAFNPSEYQAITEASSNQRLTNIKSQAADSLRELSQTCATCSMTEIKSSREFSDQVLHSKQSHFYETFWMNSAIL
ASWYALMGAQTITSGHSFSSATEITPSVAFTEVPSLFPSKKSAKRTILSSSLEESITLSSNLDVNLCLDKTCLSIVPSQTISSDLMNSDL
TSKMTTDELSVSENILKLLKIRQYGITMGPTEVLNQESLLDMEKSKGSHTLFKLHPSDSSLDFELNLQIYPDVTLKTYSEITHANDFKNN
LPPLTGSVPDFSEVTTNVAFYTVSATPALSIQTSSSMSVIRPDWPYFTDYMTSLKKEVKTSSEWSKWELQPSVQYQEFPTASRHLPFTRS
LTLSSLESILAPQRLMISDFSCVRYYGDSYLEFQNVALNPQNNISLEFQTFSSYGLLLYVKQDSNLVDGFFIQLFIENGTLKYHFYCPGE
AKFKSINTTVRVDNGQKYTLLIRQELDPCNAELTILGRNTQICESINHVLGKPLPKSGSVFIGGFPDLHGKIQMPVPVKNFTGCIEVIEI
NNWRSFIPSKAVKNYHINNCRSQGFMLSPTASFVDASDVTQGVDTMWTSVSPSVAAPSVCQQDVCHNGGTCHAIFLSSGIVSFQCDCPLH
FTGRFCEKDAGLFFPSFNGNSYLELPFLKFVLEKEHNRTVTIYLTIKTNSLNGTILYSNGNNCGKQFLHLFLVEGRPSVKYGCGNSQNIL
TVSANYSINTNAFTPITIRYTTPVGSPGVVCMIEMTADGKPPVQKKDTEISHASQAYFESMFLGHIPANVQIHKKAGPVYGFRGCILDLQ
VNNKEFFIIDEARHGKNIENCHVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFASCENNPCGNGATCVPKSGTDIVCLCPYGRS
GPLCTDAINITQPRFSGTDAFGYTSFLAYSRISDISFHYEFHLKFQLANNHSALQNNLIFFTGQKGHGLNGDDFLAVGLLNGSVVYSYNL
GSGIASIRSEPLNLSLGVHTVHLGKFFQEGWLKVDDHKNKSIIAPGRLVGLNVFSQFYVGGYSEYTPDLLPNGADFKNGFQGCIFTLQVR
TEKDGHFRGLGNPEGHPNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPH
GYTCFCPLGTTGIYCEQALILIVILEKPKPAERKVKKEALSISDPSFRSNELSWMSFASFHVRKKTHIQLQFQPLAADGILFYAAQHLKA
QSGDFLCISLVNSSVQLRYNLGDRTIILETLQKVTINGSTWHIIKAGRVGAEGYLDLDGINVTEKASTKMSSLDTNTDFYIGGVSSLNLV
NPMAIENEPVGFQGCIRQVIINNQELQLTEFGAKGGSNVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNLCL
HQSLCIPDQSFSYSCLCTLGWVGRYCENKTSFSTAKFMGNSYIKYIDPNYRMRNLQFTTISLNFSTTKTEGLIVWMGIAQNEENDFLAIG
LHNQTLKIAVNLGERISVPMSYNNGTFCCNKWHHVVVIQNQTLIKAYINNSLILSEDIDPHKNFVALNYDGICYLGGFEYGRKVNIVTQE

--------------------------------------------------------------

>34786_34786_15_GRIK2-EYS_GRIK2_chr6_101847268_ENST00000413795_EYS_chr6_65767620_ENST00000503581_length(amino acids)=2541AA_BP=71
MRSPLDASSFLPEPRSRTLDRGSGCRACGHRNTMKIIFPILSNPVFRRTVKLLLCLLWIGYSQGTTHVLRFGTQCEIDIDECASHPCKNG
ATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMNPCKNN
STCTDLYKSYRCECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDAN
QHCICREEFEGKNCEIDVKDCLFLSCQDYGDCEDMVNNFRCICRPGFSGSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFC
ELDVNKCKISPCLDEENCVYRTDGYNCLCAPGYTGINCEINLDECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETNANDCLSNPCLH
GRCTELINEYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTCICPRGYTGAYCEKSIDNCAEPELNSVICLNGGICVDGPGH
TFDCRCLPGFSGQFCEININECSSSPCLHGADCEDHINGYVCKCQPGWSGHHCENELECIPNSCVHELCMENEPGSTCLCTPGFMTCSIG
LLCGDEIRRITCLTPIFQRTDPISTQTYTIPPSETLVSSFPSIKATRIPAIMDTYPVDQGPKQTGIVKHDILPTTGLATLRISTPLESYL
LQELIVTRELSAKHSLLSSADVSSSRFLNFGIRDPAQIVQDKTSVSHMPIRTSAATLGFFFPDRRARTPFIMSSLMSDFIFPTQSLLFEN
CQTVALSATPTTSVIRSIPGADIELNRQSLLSRGFLLIAASISATPVVSRGAQEDIEEYSADSLISRREHWRLLSPSMSPIFPAKVIISK
QVTILNSSALHRFSTKAFNPSEYQAITEASSNQRLTNIKSQAADSLRELSQTCATCSMTEIKSSREFSDQVLHSKQSHFYETFWMNSAIL
ASWYALMGAQTITSGHSFSSATEITPSVAFTEVPSLFPSKKSAKRTILSSSLEESITLSSNLDVNLCLDKTCLSIVPSQTISSDLMNSDL
TSKMTTDELSVSENILKLLKIRQYGITMGPTEVLNQESLLDMEKSKGSHTLFKLHPSDSSLDFELNLQIYPDVTLKTYSEITHANDFKNN
LPPLTGSVPDFSEVTTNVAFYTVSATPALSIQTSSSMSVIRPDWPYFTDYMTSLKKEVKTSSEWSKWELQPSVQYQEFPTASRHLPFTRS
LTLSSLESILAPQRLMISDFSCVRYYGDSYLEFQNVALNPQNNISLEFQTFSSYGLLLYVKQDSNLVDGFFIQLFIENGTLKYHFYCPGE
AKFKSINTTVRVDNGQKYTLLIRQELDPCNAELTILGRNTQICESINHVLGKPLPKSGSVFIGGFPDLHGKIQMPVPVKNFTGCIEVIEI
NNWRSFIPSKAVKNYHINNCRSQGFMLSPTASFVDASDVTQGVDTMWTSVSPSVAAPSVCQQDVCHNGGTCHAIFLSSGIVSFQCDCPLH
FTGRFCEKDAGLFFPSFNGNSYLELPFLKFVLEKEHNRTVTIYLTIKTNSLNGTILYSNGNNCGKQFLHLFLVEGRPSVKYGCGNSQNIL
TVSANYSINTNAFTPITIRYTTPVGSPGVVCMIEMTADGKPPVQKKDTEISHASQAYFESMFLGHIPANVQIHKKAGPVYGFRGCILDLQ
VNNKEFFIIDEARHGKNIENCHVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFASCENNPCGNGATCVPKSGTDIVCLCPYGRS
GPLCTDAINITQPRFSGTDAFGYTSFLAYSRISDISFHYEFHLKFQLANNHSALQNNLIFFTGQKGHGLNGDDFLAVGLLNGSVVYSYNL
GSGIASIRSEPLNLSLGVHTVHLGKFFQEGWLKVDDHKNKSIIAPGRLVGLNVFSQFYVGGYSEYTPDLLPNGADFKNGFQGCIFTLQVR
TEKDGHFRGLGNPEGHPNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPH
GYTCFCPLGTTGIYCEQALSISDPSFRSNELSWMSFASFHVRKKTHIQLQFQPLAADGILFYAAQHLKAQSGDFLCISLVNSSVQLRYNL
GDRTIILETLQKVTINGSTWHIIKAGRVGAEGYLDLDGINVTEKASTKMSSLDTNTDFYIGGVSSLNLVNPMAIENEPVGFQGCIRQVII
NNQELQLTEFGAKGGSNVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNLCLHQSLCIPDQSFSYSCLCTLGW
VGRYCENKTSFSTAKFMGNSYIKYIDPNYRMRNLQFTTISLNFSTTKTEGLIVWMGIAQNEENDFLAIGLHNQTLKIAVNLGERISVPMS
YNNGTFCCNKWHHVVVIQNQTLIKAYINNSLILSEDIDPHKNFVALNYDGICYLGGFEYGRKVNIVTQEIFKTNFVGKIKDVVFFQEPKN

--------------------------------------------------------------

>34786_34786_16_GRIK2-EYS_GRIK2_chr6_101847268_ENST00000421544_EYS_chr6_65767620_ENST00000370616_length(amino acids)=2563AA_BP=71
MRSPLDASSFLPEPRSRTLDRGSGCRACGHRNTMKIIFPILSNPVFRRTVKLLLCLLWIGYSQGTTHVLRFGTQCEIDIDECASHPCKNG
ATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMNPCKNN
STCTDLYKSYRCECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDAN
QHCICREEFEGKNCEIDVKDCLFLSCQDYGDCEDMVNNFRCICRPGFSGSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFC
ELDVNKCKISPCLDEENCVYRTDGYNCLCAPGYTGINCEINLDECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETNANDCLSNPCLH
GRCTELINEYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTCICPRGYTGAYCEKSIDNCAEPELNSVICLNGGICVDGPGH
TFDCRCLPGFSGQFCEININECSSSPCLHGADCEDHINGYVCKCQPGWSGHHCENELECIPNSCVHELCMENEPGSTCLCTPGFMTCSIG
LLCGDEIRRITCLTPIFQRTDPISTQTYTIPPSETLVSSFPSIKATRIPAIMDTYPVDQGPKQTGIVKHDILPTTGLATLRISTPLESYL
LQELIVTRELSAKHSLLSSADVSSSRFLNFGIRDPAQIVQDKTSVSHMPIRTSAATLGFFFPDRRARTPFIMSSLMSDFIFPTQSLLFEN
CQTVALSATPTTSVIRSIPGADIELNRQSLLSRGFLLIAASISATPVVSRGAQEDIEEYSADSLISRREHWRLLSPSMSPIFPAKVIISK
QVTILNSSALHRFSTKAFNPSEYQAITEASSNQRLTNIKSQAADSLRELSQTCATCSMTEIKSSREFSDQVLHSKQSHFYETFWMNSAIL
ASWYALMGAQTITSGHSFSSATEITPSVAFTEVPSLFPSKKSAKRTILSSSLEESITLSSNLDVNLCLDKTCLSIVPSQTISSDLMNSDL
TSKMTTDELSVSENILKLLKIRQYGITMGPTEVLNQESLLDMEKSKGSHTLFKLHPSDSSLDFELNLQIYPDVTLKTYSEITHANDFKNN
LPPLTGSVPDFSEVTTNVAFYTVSATPALSIQTSSSMSVIRPDWPYFTDYMTSLKKEVKTSSEWSKWELQPSVQYQEFPTASRHLPFTRS
LTLSSLESILAPQRLMISDFSCVRYYGDSYLEFQNVALNPQNNISLEFQTFSSYGLLLYVKQDSNLVDGFFIQLFIENGTLKYHFYCPGE
AKFKSINTTVRVDNGQKYTLLIRQELDPCNAELTILGRNTQICESINHVLGKPLPKSGSVFIGGFPDLHGKIQMPVPVKNFTGCIEVIEI
NNWRSFIPSKAVKNYHINNCRSQGFMLSPTASFVDASDVTQGVDTMWTSVSPSVAAPSVCQQDVCHNGGTCHAIFLSSGIVSFQCDCPLH
FTGRFCEKDAGLFFPSFNGNSYLELPFLKFVLEKEHNRTVTIYLTIKTNSLNGTILYSNGNNCGKQFLHLFLVEGRPSVKYGCGNSQNIL
TVSANYSINTNAFTPITIRYTTPVGSPGVVCMIEMTADGKPPVQKKDTEISHASQAYFESMFLGHIPANVQIHKKAGPVYGFRGCILDLQ
VNNKEFFIIDEARHGKNIENCHVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFASCENNPCGNGATCVPKSGTDIVCLCPYGRS
GPLCTDAINITQPRFSGTDAFGYTSFLAYSRISDISFHYEFHLKFQLANNHSALQNNLIFFTGQKGHGLNGDDFLAVGLLNGSVVYSYNL
GSGIASIRSEPLNLSLGVHTVHLGKFFQEGWLKVDDHKNKSIIAPGRLVGLNVFSQFYVGGYSEYTPDLLPNGADFKNGFQGCIFTLQVR
TEKDGHFRGLGNPEGHPNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPH
GYTCFCPLGTTGIYCEQALILIVILEKPKPAERKVKKEALSISDPSFRSNELSWMSFASFHVRKKTHIQLQFQPLAADGILFYAAQHLKA
QSGDFLCISLVNSSVQLRYNLGDRTIILETLQKVTINGSTWHIIKAGRVGAEGYLDLDGINVTEKASTKMSSLDTNTDFYIGGVSSLNLV
NPMAIENEPVGFQGCIRQVIINNQELQLTEFGAKGGSNVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNLCL
HQSLCIPDQSFSYSCLCTLGWVGRYCENKTSFSTAKFMGNSYIKYIDPNYRMRNLQFTTISLNFSTTKTEGLIVWMGIAQNEENDFLAIG
LHNQTLKIAVNLGERISVPMSYNNGTFCCNKWHHVVVIQNQTLIKAYINNSLILSEDIDPHKNFVALNYDGICYLGGFEYGRKVNIVTQE

--------------------------------------------------------------

>34786_34786_17_GRIK2-EYS_GRIK2_chr6_101847268_ENST00000421544_EYS_chr6_65767620_ENST00000370621_length(amino acids)=2562AA_BP=71
MRSPLDASSFLPEPRSRTLDRGSGCRACGHRNTMKIIFPILSNPVFRRTVKLLLCLLWIGYSQGTTHVLRFGTQCEIDIDECASHPCKNG
ATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMNPCKNN
STCTDLYKSYRCECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDAN
QHCICREEFEGKNCEIDVKDCLFLSCQDYGDCEDMVNNFRCICRPGFSGSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFC
ELDVNKCKISPCLDEENCVYRTDGYNCLCAPGYTGINCEINLDECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETNANDCLSNPCLH
GRCTELINEYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTCICPRGYTGAYCEKSIDNCAEPELNSVICLNGGICVDGPGH
TFDCRCLPGFSGQFCEININECSSSPCLHGADCEDHINGYVCKCQPGWSGHHCENELECIPNSCVHELCMENEPGSTCLCTPGFMTCSIG
LLCGDEIRRITCLTPIFQRTDPISTQTYTIPPSETLVSSFPSIKATRIPAIMDTYPVDQGPKQTGIVKHDILPTTGLATLRISTPLESYL
LQELIVTRELSAKHSLLSSADVSSSRFLNFGIRDPAQIVQDKTSVSHMPIRTSAATLGFFFPDRRARTPFIMSSLMSDFIFPTQSLLFEN
CQTVALSATPTTSVIRSIPGADIELNRQSLLSRGFLLIAASISATPVVSRGAQEDIEEYSADSLISRREHWRLLSPSMSPIFPAKVIISK
QVTILNSSALHRFSTKAFNPSEYQAITEASSNQRLTNIKSQAADSLRELSQTCATCSMTEIKSSREFSDQVLHSKQSHFYETFWMNSAIL
ASWYALMGAQTITSGHSFSSATEITPSVAFTEVPSLFPSKKSAKRTILSSSLEESITLSSNLDVNLCLDKTCLSIVPSQTISSDLMNSDL
TSKMTTDELSVSENILKLLKIRQYGITMGPTEVLNQESLLDMEKSKGSHTLFKLHPSDSSLDFELNLQIYPDVTLKTYSEITHANDFKNN
LPPLTGSVPDFSEVTTNVAFYTVSATPALSIQTSSSMSVIRPDWPYFTDYMTSLKKEVKTSSEWSKWELQPSVQYQEFPTASRHLPFTRS
LTLSSLESILAPQRLMISDFSCVRYYGDSYLEFQNVALNPQNNISLEFQTFSSYGLLLYVKQDSNLVDGFFIQLFIENGTLKYHFYCPGE
AKFKSINTTVRVDNGQKYTLLIRQELDPCNAELTILGRNTQICESINHVLGKPLPKSGSVFIGGFPDLHGKIQMPVPVKNFTGCIEVIEI
NNWRSFIPSKAVKNYHINNCRSQGFMLSPTASFVDASDVTQGVDTMWTSVSPSVAAPSVCQQDVCHNGGTCHAIFLSSGIVSFQCDCPLH
FTGRFCEKDAGLFFPSFNGNSYLELPFLKFVLEKEHNRTVTIYLTIKTNSLNGTILYSNGNNCGKQFLHLFLVEGRPSVKYGCGNSQNIL
TVSANYSINTNAFTPITIRYTTPVGSPGVVCMIEMTADGKPPVQKKDTEISHASQAYFESMFLGHIPANVQIHKKAGPVYGFRGCILDLQ
VNNKEFFIIDEARHGKNIENCHVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFASCENNPCGNGATCVPKSGTDIVCLCPYGRS
GPLCTDAINITQPRFSGTDAFGYTSFLAYSRISDISFHYEFHLKFQLANNHSALQNNLIFFTGQKGHGLNGDDFLAVGLLNGSVVYSYNL
GSGIASIRSEPLNLSLGVHTVHLGKFFQEGWLKVDDHKNKSIIAPGRLVGLNVFSQFYVGGYSEYTPDLLPNGADFKNGFQGCIFTLQVR
TEKDGHFRGLGNPEGHPNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPH
GYTCFCPLGTTGIYCEQALILIVILEKPKPAERKVKKEALSISDPSFRSNELSWMSFASFHVRKKTHIQLQFQPLAADGILFYAAQHLKA
QSGDFLCISLVNSSVQLRYNLGDRTIILETLQKVTINGSTWHIIKAGRVGAEGYLDLDGINVTEKASTKMSSLDTNTDFYIGGVSSLNLV
NPMAIENEPVGFQGCIRQVIINNQELQLTEFGAKGGSNVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNLCL
HQSLCIPDQSFSYSCLCTLGWVGRYCENKTSFSTAKFMGNSYIKYIDPNYRMRNLQFTTISLNFSTTKTEGLIVWMGIAQNEENDFLAIG
LHNQTLKIAVNLGERISVPMSYNNGTFCCNKWHHVVVIQNQTLIKAYINNSLILSEDIDPHKNFVALNYDGICYLGGFEYGRKVNIVTQE

--------------------------------------------------------------

>34786_34786_18_GRIK2-EYS_GRIK2_chr6_101847268_ENST00000421544_EYS_chr6_65767620_ENST00000503581_length(amino acids)=2541AA_BP=71
MRSPLDASSFLPEPRSRTLDRGSGCRACGHRNTMKIIFPILSNPVFRRTVKLLLCLLWIGYSQGTTHVLRFGTQCEIDIDECASHPCKNG
ATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMNPCKNN
STCTDLYKSYRCECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDAN
QHCICREEFEGKNCEIDVKDCLFLSCQDYGDCEDMVNNFRCICRPGFSGSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFC
ELDVNKCKISPCLDEENCVYRTDGYNCLCAPGYTGINCEINLDECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETNANDCLSNPCLH
GRCTELINEYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTCICPRGYTGAYCEKSIDNCAEPELNSVICLNGGICVDGPGH
TFDCRCLPGFSGQFCEININECSSSPCLHGADCEDHINGYVCKCQPGWSGHHCENELECIPNSCVHELCMENEPGSTCLCTPGFMTCSIG
LLCGDEIRRITCLTPIFQRTDPISTQTYTIPPSETLVSSFPSIKATRIPAIMDTYPVDQGPKQTGIVKHDILPTTGLATLRISTPLESYL
LQELIVTRELSAKHSLLSSADVSSSRFLNFGIRDPAQIVQDKTSVSHMPIRTSAATLGFFFPDRRARTPFIMSSLMSDFIFPTQSLLFEN
CQTVALSATPTTSVIRSIPGADIELNRQSLLSRGFLLIAASISATPVVSRGAQEDIEEYSADSLISRREHWRLLSPSMSPIFPAKVIISK
QVTILNSSALHRFSTKAFNPSEYQAITEASSNQRLTNIKSQAADSLRELSQTCATCSMTEIKSSREFSDQVLHSKQSHFYETFWMNSAIL
ASWYALMGAQTITSGHSFSSATEITPSVAFTEVPSLFPSKKSAKRTILSSSLEESITLSSNLDVNLCLDKTCLSIVPSQTISSDLMNSDL
TSKMTTDELSVSENILKLLKIRQYGITMGPTEVLNQESLLDMEKSKGSHTLFKLHPSDSSLDFELNLQIYPDVTLKTYSEITHANDFKNN
LPPLTGSVPDFSEVTTNVAFYTVSATPALSIQTSSSMSVIRPDWPYFTDYMTSLKKEVKTSSEWSKWELQPSVQYQEFPTASRHLPFTRS
LTLSSLESILAPQRLMISDFSCVRYYGDSYLEFQNVALNPQNNISLEFQTFSSYGLLLYVKQDSNLVDGFFIQLFIENGTLKYHFYCPGE
AKFKSINTTVRVDNGQKYTLLIRQELDPCNAELTILGRNTQICESINHVLGKPLPKSGSVFIGGFPDLHGKIQMPVPVKNFTGCIEVIEI
NNWRSFIPSKAVKNYHINNCRSQGFMLSPTASFVDASDVTQGVDTMWTSVSPSVAAPSVCQQDVCHNGGTCHAIFLSSGIVSFQCDCPLH
FTGRFCEKDAGLFFPSFNGNSYLELPFLKFVLEKEHNRTVTIYLTIKTNSLNGTILYSNGNNCGKQFLHLFLVEGRPSVKYGCGNSQNIL
TVSANYSINTNAFTPITIRYTTPVGSPGVVCMIEMTADGKPPVQKKDTEISHASQAYFESMFLGHIPANVQIHKKAGPVYGFRGCILDLQ
VNNKEFFIIDEARHGKNIENCHVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFASCENNPCGNGATCVPKSGTDIVCLCPYGRS
GPLCTDAINITQPRFSGTDAFGYTSFLAYSRISDISFHYEFHLKFQLANNHSALQNNLIFFTGQKGHGLNGDDFLAVGLLNGSVVYSYNL
GSGIASIRSEPLNLSLGVHTVHLGKFFQEGWLKVDDHKNKSIIAPGRLVGLNVFSQFYVGGYSEYTPDLLPNGADFKNGFQGCIFTLQVR
TEKDGHFRGLGNPEGHPNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPH
GYTCFCPLGTTGIYCEQALSISDPSFRSNELSWMSFASFHVRKKTHIQLQFQPLAADGILFYAAQHLKAQSGDFLCISLVNSSVQLRYNL
GDRTIILETLQKVTINGSTWHIIKAGRVGAEGYLDLDGINVTEKASTKMSSLDTNTDFYIGGVSSLNLVNPMAIENEPVGFQGCIRQVII
NNQELQLTEFGAKGGSNVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNLCLHQSLCIPDQSFSYSCLCTLGW
VGRYCENKTSFSTAKFMGNSYIKYIDPNYRMRNLQFTTISLNFSTTKTEGLIVWMGIAQNEENDFLAIGLHNQTLKIAVNLGERISVPMS
YNNGTFCCNKWHHVVVIQNQTLIKAYINNSLILSEDIDPHKNFVALNYDGICYLGGFEYGRKVNIVTQEIFKTNFVGKIKDVVFFQEPKN

--------------------------------------------------------------

Top

Fusion Protein Functional Features

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr6:101847268/chr6:65767620)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
GRIK2 Q13002	EYS Q5T1H1
FUNCTION: Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist (PubMed:28180184). Modulates cell surface expression of NETO2 (By similarity). {ECO:0000250\|UniProtKB:P39087, ECO:0000269\|PubMed:28180184}.; FUNCTION: Independent of its ionotropic glutamate receptor activity, acts as a thermoreceptor conferring sensitivity to cold temperatures (PubMed:31474366). Functions in dorsal root ganglion neurons (By similarity). {ECO:0000250\|UniProtKB:P39087, ECO:0000269\|PubMed:31474366}.	FUNCTION: Required to maintain the integrity of photoreceptor cells (PubMed:18836446). Specifically required for normal morphology of the photoreceptor ciliary pocket, and might thus facilitate protein trafficking between the photoreceptor inner and outer segments via the transition zone (By similarity). {ECO:0000250\|UniProtKB:B8JI71, ECO:0000269\|PubMed:18836446}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page
* Minus value of BPloci means that the break pointn is located before the CDS.

- Retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000342421

1004_1040

595.0

Domain

EGF-like 16%3B calcium-binding

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000342421

1042_1077

595.0

Domain

EGF-like 17

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000342421

1079_1115

595.0

Domain

EGF-like 18

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000342421

1117_1159

595.0

Domain

EGF-like 19

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000342421

1161_1197

595.0

Domain

EGF-like 20%3B calcium-binding

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000342421

170_212

595.0

Domain

EGF-like 1

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000342421

1883_2063

595.0

Domain

Laminin G-like 1

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000342421

2099_2140

595.0

Domain

EGF-like 21

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000342421

213_254

595.0

Domain

EGF-like 2

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000342421

2145_2339

595.0

Domain

Laminin G-like 2

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000342421

2335_2368

595.0

Domain

EGF-like 22

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000342421

2371_2408

595.0

Domain

EGF-like 23

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000342421

2419_2609

595.0

Domain

Laminin G-like 3

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000342421

256_292

595.0

Domain

EGF-like 3

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000342421

2610_2646

595.0

Domain

EGF-like 24

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000342421

2648_2689

595.0

Domain

EGF-like 25

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000342421

2717_2895

595.0

Domain

Laminin G-like 4

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000342421

2896_2932

595.0

Domain

EGF-like 26

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000342421

2933_2970

595.0

Domain

EGF-like 27

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000342421

2975_3165

595.0

Domain

Laminin G-like 5

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000342421

332_368

595.0

Domain

EGF-like 4

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000342421

370_406

595.0

Domain

EGF-like 5

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000342421

567_602

595.0

Domain

EGF-like 6

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000342421

643_679

595.0

Domain

EGF-like 7

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000342421

681_720

595.0

Domain

EGF-like 8%3B calcium-binding

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000342421

733_769

595.0

Domain

EGF-like 9%3B calcium-binding

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000342421

771_807

595.0

Domain

EGF-like 10%3B calcium-binding

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000342421

809_847

595.0

Domain

EGF-like 11

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000342421

849_888

595.0

Domain

EGF-like 12

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000342421

890_926

595.0

Domain

EGF-like 13

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000342421

928_964

595.0

Domain

EGF-like 14%3B calcium-binding

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000342421

966_1002

595.0

Domain

EGF-like 15

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370616

1004_1040

674.3333333333334

3166.0

Domain

EGF-like 16%3B calcium-binding

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370616

1042_1077

674.3333333333334

3166.0

Domain

EGF-like 17

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370616

1079_1115

674.3333333333334

3166.0

Domain

EGF-like 18

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370616

1117_1159

674.3333333333334

3166.0

Domain

EGF-like 19

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370616

1161_1197

674.3333333333334

3166.0

Domain

EGF-like 20%3B calcium-binding

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370616

1883_2063

674.3333333333334

3166.0

Domain

Laminin G-like 1

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370616

2099_2140

674.3333333333334

3166.0

Domain

EGF-like 21

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370616

2145_2339

674.3333333333334

3166.0

Domain

Laminin G-like 2

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370616

2335_2368

674.3333333333334

3166.0

Domain

EGF-like 22

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370616

2371_2408

674.3333333333334

3166.0

Domain

EGF-like 23

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370616

2419_2609

674.3333333333334

3166.0

Domain

Laminin G-like 3

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370616

2610_2646

674.3333333333334

3166.0

Domain

EGF-like 24

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370616

2648_2689

674.3333333333334

3166.0

Domain

EGF-like 25

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370616

2717_2895

674.3333333333334

3166.0

Domain

Laminin G-like 4

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370616

2896_2932

674.3333333333334

3166.0

Domain

EGF-like 26

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370616

2933_2970

674.3333333333334

3166.0

Domain

EGF-like 27

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370616

2975_3165

674.3333333333334

3166.0

Domain

Laminin G-like 5

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370616

681_720

674.3333333333334

3166.0

Domain

EGF-like 8%3B calcium-binding

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370616

733_769

674.3333333333334

3166.0

Domain

EGF-like 9%3B calcium-binding

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370616

771_807

674.3333333333334

3166.0

Domain

EGF-like 10%3B calcium-binding

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370616

809_847

674.3333333333334

3166.0

Domain

EGF-like 11

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370616

849_888

674.3333333333334

3166.0

Domain

EGF-like 12

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370616

890_926

674.3333333333334

3166.0

Domain

EGF-like 13

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370616

928_964

674.3333333333334

3166.0

Domain

EGF-like 14%3B calcium-binding

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370616

966_1002

674.3333333333334

3166.0

Domain

EGF-like 15

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370618

1004_1040

595.0

Domain

EGF-like 16%3B calcium-binding

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370618

1042_1077

595.0

Domain

EGF-like 17

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370618

1079_1115

595.0

Domain

EGF-like 18

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370618

1117_1159

595.0

Domain

EGF-like 19

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370618

1161_1197

595.0

Domain

EGF-like 20%3B calcium-binding

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370618

170_212

595.0

Domain

EGF-like 1

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370618

1883_2063

595.0

Domain

Laminin G-like 1

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370618

2099_2140

595.0

Domain

EGF-like 21

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370618

213_254

595.0

Domain

EGF-like 2

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370618

2145_2339

595.0

Domain

Laminin G-like 2

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370618

2335_2368

595.0

Domain

EGF-like 22

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370618

2371_2408

595.0

Domain

EGF-like 23

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370618

2419_2609

595.0

Domain

Laminin G-like 3

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370618

256_292

595.0

Domain

EGF-like 3

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370618

2610_2646

595.0

Domain

EGF-like 24

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370618

2648_2689

595.0

Domain

EGF-like 25

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370618

2717_2895

595.0

Domain

Laminin G-like 4

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370618

2896_2932

595.0

Domain

EGF-like 26

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370618

2933_2970

595.0

Domain

EGF-like 27

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370618

2975_3165

595.0

Domain

Laminin G-like 5

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370618

332_368

595.0

Domain

EGF-like 4

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370618

370_406

595.0

Domain

EGF-like 5

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370618

567_602

595.0

Domain

EGF-like 6

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370618

643_679

595.0

Domain

EGF-like 7

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370618

681_720

595.0

Domain

EGF-like 8%3B calcium-binding

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370618

733_769

595.0

Domain

EGF-like 9%3B calcium-binding

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370618

771_807

595.0

Domain

EGF-like 10%3B calcium-binding

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370618

809_847

595.0

Domain

EGF-like 11

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370618

849_888

595.0

Domain

EGF-like 12

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370618

890_926

595.0

Domain

EGF-like 13

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370618

928_964

595.0

Domain

EGF-like 14%3B calcium-binding

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370618

966_1002

595.0

Domain

EGF-like 15

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370621

1004_1040

674.3333333333334

3166.0

Domain

EGF-like 16%3B calcium-binding

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370621

1042_1077

674.3333333333334

3166.0

Domain

EGF-like 17

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370621

1079_1115

674.3333333333334

3166.0

Domain

EGF-like 18

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370621

1117_1159

674.3333333333334

3166.0

Domain

EGF-like 19

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370621

1161_1197

674.3333333333334

3166.0

Domain

EGF-like 20%3B calcium-binding

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370621

1883_2063

674.3333333333334

3166.0

Domain

Laminin G-like 1

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370621

2099_2140

674.3333333333334

3166.0

Domain

EGF-like 21

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370621

2145_2339

674.3333333333334

3166.0

Domain

Laminin G-like 2

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370621

2335_2368

674.3333333333334

3166.0

Domain

EGF-like 22

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370621

2371_2408

674.3333333333334

3166.0

Domain

EGF-like 23

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370621

2419_2609

674.3333333333334

3166.0

Domain

Laminin G-like 3

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370621

2610_2646

674.3333333333334

3166.0

Domain

EGF-like 24

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370621

2648_2689

674.3333333333334

3166.0

Domain

EGF-like 25

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370621

2717_2895

674.3333333333334

3166.0

Domain

Laminin G-like 4

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370621

2896_2932

674.3333333333334

3166.0

Domain

EGF-like 26

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370621

2933_2970

674.3333333333334

3166.0

Domain

EGF-like 27

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370621

2975_3165

674.3333333333334

3166.0

Domain

Laminin G-like 5

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370621

681_720

674.3333333333334

3166.0

Domain

EGF-like 8%3B calcium-binding

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370621

733_769

674.3333333333334

3166.0

Domain

EGF-like 9%3B calcium-binding

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370621

771_807

674.3333333333334

3166.0

Domain

EGF-like 10%3B calcium-binding

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370621

809_847

674.3333333333334

3166.0

Domain

EGF-like 11

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370621

849_888

674.3333333333334

3166.0

Domain

EGF-like 12

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370621

890_926

674.3333333333334

3166.0

Domain

EGF-like 13

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370621

928_964

674.3333333333334

3166.0

Domain

EGF-like 14%3B calcium-binding

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370621

966_1002

674.3333333333334

3166.0

Domain

EGF-like 15

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000393380

1004_1040

620.0

Domain

EGF-like 16%3B calcium-binding

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000393380

1042_1077

620.0

Domain

EGF-like 17

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000393380

1079_1115

620.0

Domain

EGF-like 18

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000393380

1117_1159

620.0

Domain

EGF-like 19

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000393380

1161_1197

620.0

Domain

EGF-like 20%3B calcium-binding

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000393380

170_212

620.0

Domain

EGF-like 1

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000393380

1883_2063

620.0

Domain

Laminin G-like 1

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000393380

2099_2140

620.0

Domain

EGF-like 21

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000393380

213_254

620.0

Domain

EGF-like 2

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000393380

2145_2339

620.0

Domain

Laminin G-like 2

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000393380

2335_2368

620.0

Domain

EGF-like 22

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000393380

2371_2408

620.0

Domain

EGF-like 23

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000393380

2419_2609

620.0

Domain

Laminin G-like 3

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000393380

256_292

620.0

Domain

EGF-like 3

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000393380

2610_2646

620.0

Domain

EGF-like 24

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000393380

2648_2689

620.0

Domain

EGF-like 25

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000393380

2717_2895

620.0

Domain

Laminin G-like 4

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000393380

2896_2932

620.0

Domain

EGF-like 26

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000393380

2933_2970

620.0

Domain

EGF-like 27

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000393380

2975_3165

620.0

Domain

Laminin G-like 5

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000393380

332_368

620.0

Domain

EGF-like 4

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000393380

370_406

620.0

Domain

EGF-like 5

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000393380

567_602

620.0

Domain

EGF-like 6

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000393380

643_679

620.0

Domain

EGF-like 7

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000393380

681_720

620.0

Domain

EGF-like 8%3B calcium-binding

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000393380

733_769

620.0

Domain

EGF-like 9%3B calcium-binding

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000393380

771_807

620.0

Domain

EGF-like 10%3B calcium-binding

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000393380

809_847

620.0

Domain

EGF-like 11

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000393380

849_888

620.0

Domain

EGF-like 12

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000393380

890_926

620.0

Domain

EGF-like 13

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000393380

928_964

620.0

Domain

EGF-like 14%3B calcium-binding

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000393380

966_1002

620.0

Domain

EGF-like 15

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000503581

1004_1040

674.3333333333334

3145.0

Domain

EGF-like 16%3B calcium-binding

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000503581

1042_1077

674.3333333333334

3145.0

Domain

EGF-like 17

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000503581

1079_1115

674.3333333333334

3145.0

Domain

EGF-like 18

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000503581

1117_1159

674.3333333333334

3145.0

Domain

EGF-like 19

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000503581

1161_1197

674.3333333333334

3145.0

Domain

EGF-like 20%3B calcium-binding

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000503581

1883_2063

674.3333333333334

3145.0

Domain

Laminin G-like 1

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000503581

2099_2140

674.3333333333334

3145.0

Domain

EGF-like 21

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000503581

2145_2339

674.3333333333334

3145.0

Domain

Laminin G-like 2

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000503581

2335_2368

674.3333333333334

3145.0

Domain

EGF-like 22

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000503581

2371_2408

674.3333333333334

3145.0

Domain

EGF-like 23

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000503581

2419_2609

674.3333333333334

3145.0

Domain

Laminin G-like 3

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000503581

2610_2646

674.3333333333334

3145.0

Domain

EGF-like 24

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000503581

2648_2689

674.3333333333334

3145.0

Domain

EGF-like 25

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000503581

2717_2895

674.3333333333334

3145.0

Domain

Laminin G-like 4

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000503581

2896_2932

674.3333333333334

3145.0

Domain

EGF-like 26

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000503581

2933_2970

674.3333333333334

3145.0

Domain

EGF-like 27

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000503581

2975_3165

674.3333333333334

3145.0

Domain

Laminin G-like 5

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000503581

681_720

674.3333333333334

3145.0

Domain

EGF-like 8%3B calcium-binding

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000503581

733_769

674.3333333333334

3145.0

Domain

EGF-like 9%3B calcium-binding

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000503581

771_807

674.3333333333334

3145.0

Domain

EGF-like 10%3B calcium-binding

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000503581

809_847

674.3333333333334

3145.0

Domain

EGF-like 11

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000503581

849_888

674.3333333333334

3145.0

Domain

EGF-like 12

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000503581

890_926

674.3333333333334

3145.0

Domain

EGF-like 13

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000503581

928_964

674.3333333333334

3145.0

Domain

EGF-like 14%3B calcium-binding

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000503581

966_1002

674.3333333333334

3145.0

Domain

EGF-like 15

- Not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

GRIK2

chr6:101847268

chr6:65767620

ENST00000318991

516_518

38.333333333333336

870.0

Region

Glutamate binding

Hgene

GRIK2

chr6:101847268

chr6:65767620

ENST00000318991

689_690

38.333333333333336

870.0

Region

Glutamate binding

Hgene

GRIK2

chr6:101847268

chr6:65767620

ENST00000369137

516_518

38.333333333333336

833.0

Region

Glutamate binding

Hgene

GRIK2

chr6:101847268

chr6:65767620

ENST00000369137

689_690

38.333333333333336

833.0

Region

Glutamate binding

Hgene

GRIK2

chr6:101847268

chr6:65767620

ENST00000369138

516_518

38.333333333333336

1270.3333333333333

Region

Glutamate binding

Hgene

GRIK2

chr6:101847268

chr6:65767620

ENST00000369138

689_690

38.333333333333336

1270.3333333333333

Region

Glutamate binding

Hgene

GRIK2

chr6:101847268

chr6:65767620

ENST00000413795

516_518

38.333333333333336

1247.3333333333333

Region

Glutamate binding

Hgene

GRIK2

chr6:101847268

chr6:65767620

ENST00000413795

689_690

38.333333333333336

1247.3333333333333

Region

Glutamate binding

Hgene

GRIK2

chr6:101847268

chr6:65767620

ENST00000421544

516_518

38.333333333333336

909.0

Region

Glutamate binding

Hgene

GRIK2

chr6:101847268

chr6:65767620

ENST00000421544

689_690

38.333333333333336

909.0

Region

Glutamate binding

Hgene

GRIK2

chr6:101847268

chr6:65767620

ENST00000318991

32_561

38.333333333333336

870.0

Topological domain

Extracellular

Hgene

GRIK2

chr6:101847268

chr6:65767620

ENST00000318991

583_635

38.333333333333336

870.0

Topological domain

Cytoplasmic

Hgene

GRIK2

chr6:101847268

chr6:65767620

ENST00000318991

657_819

38.333333333333336

870.0

Topological domain

Extracellular

Hgene

GRIK2

chr6:101847268

chr6:65767620

ENST00000318991

841_908

38.333333333333336

870.0

Topological domain

Cytoplasmic

Hgene

GRIK2

chr6:101847268

chr6:65767620

ENST00000369137

32_561

38.333333333333336

833.0

Topological domain

Extracellular

Hgene

GRIK2

chr6:101847268

chr6:65767620

ENST00000369137

583_635

38.333333333333336

833.0

Topological domain

Cytoplasmic

Hgene

GRIK2

chr6:101847268

chr6:65767620

ENST00000369137

657_819

38.333333333333336

833.0

Topological domain

Extracellular

Hgene

GRIK2

chr6:101847268

chr6:65767620

ENST00000369137

841_908

38.333333333333336

833.0

Topological domain

Cytoplasmic

Hgene

GRIK2

chr6:101847268

chr6:65767620

ENST00000369138

32_561

38.333333333333336

1270.3333333333333

Topological domain

Extracellular

Hgene

GRIK2

chr6:101847268

chr6:65767620

ENST00000369138

583_635

38.333333333333336

1270.3333333333333

Topological domain

Cytoplasmic

Hgene

GRIK2

chr6:101847268

chr6:65767620

ENST00000369138

657_819

38.333333333333336

1270.3333333333333

Topological domain

Extracellular

Hgene

GRIK2

chr6:101847268

chr6:65767620

ENST00000369138

841_908

38.333333333333336

1270.3333333333333

Topological domain

Cytoplasmic

Hgene

GRIK2

chr6:101847268

chr6:65767620

ENST00000413795

32_561

38.333333333333336

1247.3333333333333

Topological domain

Extracellular

Hgene

GRIK2

chr6:101847268

chr6:65767620

ENST00000413795

583_635

38.333333333333336

1247.3333333333333

Topological domain

Cytoplasmic

Hgene

GRIK2

chr6:101847268

chr6:65767620

ENST00000413795

657_819

38.333333333333336

1247.3333333333333

Topological domain

Extracellular

Hgene

GRIK2

chr6:101847268

chr6:65767620

ENST00000413795

841_908

38.333333333333336

1247.3333333333333

Topological domain

Cytoplasmic

Hgene

GRIK2

chr6:101847268

chr6:65767620

ENST00000421544

32_561

38.333333333333336

909.0

Topological domain

Extracellular

Hgene

GRIK2

chr6:101847268

chr6:65767620

ENST00000421544

583_635

38.333333333333336

909.0

Topological domain

Cytoplasmic

Hgene

GRIK2

chr6:101847268

chr6:65767620

ENST00000421544

657_819

38.333333333333336

909.0

Topological domain

Extracellular

Hgene

GRIK2

chr6:101847268

chr6:65767620

ENST00000421544

841_908

38.333333333333336

909.0

Topological domain

Cytoplasmic

Hgene

GRIK2

chr6:101847268

chr6:65767620

ENST00000318991

562_582

38.333333333333336

870.0

Transmembrane

Helical

Hgene

GRIK2

chr6:101847268

chr6:65767620

ENST00000318991

636_656

38.333333333333336

870.0

Transmembrane

Helical

Hgene

GRIK2

chr6:101847268

chr6:65767620

ENST00000318991

820_840

38.333333333333336

870.0

Transmembrane

Helical

Hgene

GRIK2

chr6:101847268

chr6:65767620

ENST00000369137

562_582

38.333333333333336

833.0

Transmembrane

Helical

Hgene

GRIK2

chr6:101847268

chr6:65767620

ENST00000369137

636_656

38.333333333333336

833.0

Transmembrane

Helical

Hgene

GRIK2

chr6:101847268

chr6:65767620

ENST00000369137

820_840

38.333333333333336

833.0

Transmembrane

Helical

Hgene

GRIK2

chr6:101847268

chr6:65767620

ENST00000369138

562_582

38.333333333333336

1270.3333333333333

Transmembrane

Helical

Hgene

GRIK2

chr6:101847268

chr6:65767620

ENST00000369138

636_656

38.333333333333336

1270.3333333333333

Transmembrane

Helical

Hgene

GRIK2

chr6:101847268

chr6:65767620

ENST00000369138

820_840

38.333333333333336

1270.3333333333333

Transmembrane

Helical

Hgene

GRIK2

chr6:101847268

chr6:65767620

ENST00000413795

562_582

38.333333333333336

1247.3333333333333

Transmembrane

Helical

Hgene

GRIK2

chr6:101847268

chr6:65767620

ENST00000413795

636_656

38.333333333333336

1247.3333333333333

Transmembrane

Helical

Hgene

GRIK2

chr6:101847268

chr6:65767620

ENST00000413795

820_840

38.333333333333336

1247.3333333333333

Transmembrane

Helical

Hgene

GRIK2

chr6:101847268

chr6:65767620

ENST00000421544

562_582

38.333333333333336

909.0

Transmembrane

Helical

Hgene

GRIK2

chr6:101847268

chr6:65767620

ENST00000421544

636_656

38.333333333333336

909.0

Transmembrane

Helical

Hgene

GRIK2

chr6:101847268

chr6:65767620

ENST00000421544

820_840

38.333333333333336

909.0

Transmembrane

Helical

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370616

170_212

674.3333333333334

3166.0

Domain

EGF-like 1

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370616

213_254

674.3333333333334

3166.0

Domain

EGF-like 2

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370616

256_292

674.3333333333334

3166.0

Domain

EGF-like 3

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370616

332_368

674.3333333333334

3166.0

Domain

EGF-like 4

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370616

370_406

674.3333333333334

3166.0

Domain

EGF-like 5

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370616

567_602

674.3333333333334

3166.0

Domain

EGF-like 6

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370616

643_679

674.3333333333334

3166.0

Domain

EGF-like 7

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370621

170_212

674.3333333333334

3166.0

Domain

EGF-like 1

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370621

213_254

674.3333333333334

3166.0

Domain

EGF-like 2

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370621

256_292

674.3333333333334

3166.0

Domain

EGF-like 3

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370621

332_368

674.3333333333334

3166.0

Domain

EGF-like 4

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370621

370_406

674.3333333333334

3166.0

Domain

EGF-like 5

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370621

567_602

674.3333333333334

3166.0

Domain

EGF-like 6

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000370621

643_679

674.3333333333334

3166.0

Domain

EGF-like 7

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000503581

170_212

674.3333333333334

3145.0

Domain

EGF-like 1

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000503581

213_254

674.3333333333334

3145.0

Domain

EGF-like 2

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000503581

256_292

674.3333333333334

3145.0

Domain

EGF-like 3

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000503581

332_368

674.3333333333334

3145.0

Domain

EGF-like 4

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000503581

370_406

674.3333333333334

3145.0

Domain

EGF-like 5

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000503581

567_602

674.3333333333334

3145.0

Domain

EGF-like 6

Tgene

EYS

chr6:101847268

chr6:65767620

ENST00000503581

643_679

674.3333333333334

3145.0

Domain

EGF-like 7

Top

Fusion Protein-Protein Interaction

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type from validated records (BIOGRID-3.4.160)

Gene

PPI interactors

Protein-protein interactors based on sequence similarity (STRING)

Gene	STRING network
GRIK2
EYS

- Retained interactions in fusion protein (protein functional feature from UniProt).

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost interactions due to fusion (protein functional feature from UniProt).

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Related Drugs to GRIK2-EYS

Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)

Hgene

Tgene

Drug

Source

PMID

Top

Related Diseases to GRIK2-EYS

Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)

Hgene

Tgene

Disease

Source

PMID

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source