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	Fusion Gene Summary
	Fusion Gene Sample Information
	Fusion ORF Analysis
	Fusion Amino Acid Sequences
	Fusion Protein Functional Features
	Fusion Protein-Protein Interaction
	Related drugs with this fusion protein
	Related disease with this fusion protein

Fusion Protein:IFT20-SUZ12

Fusion Protein Summary

Fusion gene summary

Fusion partner gene information	Fusion gene name: IFT20-SUZ12
	FusionPDB ID: 38417
	FusionGDB2.0 ID: 38417
		Hgene	Tgene
	Gene symbol	IFT20	SUZ12
	Gene ID	90410	23512
	Gene name	intraflagellar transport 20	SUZ12 polycomb repressive complex 2 subunit
	Synonyms	-	CHET9\|IMMAS\|JJAZ1
	Cytomap	17q11.2	17q11.2
	Type of gene	protein-coding	protein-coding
	Description	intraflagellar transport protein 20 homologintraflagellar transport 20 homologintraflagellar transport protein IFT20	polycomb protein SUZ12chET 9 proteinchromatin precipitated E2F target 9 proteinjoined to JAZF1 proteinsuppressor of zeste 12 protein homolog
	Modification date	20200327	20200313
	UniProtAcc	Q8IY31	Q15022
Ensembl transtripts involved in fusion gene	ENST ids	ENST00000357896, ENST00000578122, ENST00000585089, ENST00000395418, ENST00000579419, ENST00000585313, ENST00000578985,	ENST00000322652, ENST00000580398,
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)	* DoF score	3 X 3 X 3=27	10 X 8 X 5=400
	# samples	3	8
	** MAII score	log2(3/27*10)=0.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0	log2(8/400*10)=-2.32192809488736 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context (manual curation of fusion genes in FusionPDB)	PubMed: IFT20 [Title/Abstract] AND SUZ12 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)	IFT20(26656199)-SUZ12(30267305), # samples:2
Anticipated loss of major functional domain due to fusion event.	IFT20-SUZ12 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. IFT20-SUZ12 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. IFT20-SUZ12 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. IFT20-SUZ12 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. IFT20-SUZ12 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF. IFT20-SUZ12 seems lost the major protein functional domain in Tgene partner, which is a CGC due to the frame-shifted ORF. IFT20-SUZ12 seems lost the major protein functional domain in Tgene partner, which is a epigenetic factor due to the frame-shifted ORF. IFT20-SUZ12 seems lost the major protein functional domain in Tgene partner, which is a tumor suppressor due to the frame-shifted ORF.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner

Gene

GO ID

GO term

PubMed ID

Fusion gene breakpoints across IFT20 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across SUZ12 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

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Fusion Gene Sample Information

Fusion gene information from FusionGDB2.0.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	BRCA	TCGA-A8-A08F-01A	IFT20	chr17	26656199	-	SUZ12	chr17	30267305	+

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Fusion ORF Analysis

Fusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000579419	IFT20	chr17	26656199	-	ENST00000322652	SUZ12	chr17	30267305	+	4443	455	511	2400	629
ENST00000579419	IFT20	chr17	26656199	-	ENST00000580398	SUZ12	chr17	30267305	+	3978	455	511	2331	606
ENST00000395418	IFT20	chr17	26656199	-	ENST00000322652	SUZ12	chr17	30267305	+	4408	420	476	2365	629
ENST00000395418	IFT20	chr17	26656199	-	ENST00000580398	SUZ12	chr17	30267305	+	3943	420	476	2296	606
ENST00000585313	IFT20	chr17	26656199	-	ENST00000322652	SUZ12	chr17	30267305	+	4443	455	511	2400	629
ENST00000585313	IFT20	chr17	26656199	-	ENST00000580398	SUZ12	chr17	30267305	+	3978	455	511	2331	606

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000579419	ENST00000322652	IFT20	chr17	26656199	-	SUZ12	chr17	30267305	+	0.000260679	0.99973935
ENST00000579419	ENST00000580398	IFT20	chr17	26656199	-	SUZ12	chr17	30267305	+	0.000193189	0.9998068
ENST00000395418	ENST00000322652	IFT20	chr17	26656199	-	SUZ12	chr17	30267305	+	0.00024551	0.9997545
ENST00000395418	ENST00000580398	IFT20	chr17	26656199	-	SUZ12	chr17	30267305	+	0.000180448	0.9998196
ENST00000585313	ENST00000322652	IFT20	chr17	26656199	-	SUZ12	chr17	30267305	+	0.000260679	0.99973935
ENST00000585313	ENST00000580398	IFT20	chr17	26656199	-	SUZ12	chr17	30267305	+	0.000193189	0.9998068

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Fusion Amino Acid Sequences

For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

>38417_38417_1_IFT20-SUZ12_IFT20_chr17_26656199_ENST00000395418_SUZ12_chr17_30267305_ENST00000322652_length(amino acids)=629AA_BP=
MHRTLTYMSHRNSRTNIKRKTFKVDDMLSKVEKMKGEQESHSLSAHLQLTFTGFFHKNDKPSPNSENEQNSVTLEVLLVKVCHKKRKDVS
CPIRQVPTGKKQVPLNPDLNQTKPGNFPSLAVSSNEFEPSNSHMVKSYSLLFRVTRPGRREFNGMINGETNENIDVNEELPARRKRNRED
GEKTFVAQMTVFDKNRRLQLLDGEYEVAMQEMEECPISKKRATWETILDGKRLPPFETFSQGPTLQFTLRWTGETNDKSTAPIAKPLATR
NSESLHQENKPGSVKPTQTIAVKESLTTDLQTRKEKDTPNENRQKLRIFYQFLYNNNTRQQTEARDDLHCPWCTLNCRKLYSLLKHLKLC
HSRFIFNYVYHPKGARIDVSINECYDGSYAGNPQDIHRQPGFAFSRNGPVKRTPITHILVCRPKRTKASMSEFLESEDGEVEQQRTYSSG
HNRLYFHSDTCLPLRPQEMEVDSEDEKDPEWLREKTITQIEEFSDVNEGEKEVMKLWNLHVMKHGFIADNQMNHACMLFVENYGQKIIKK

--------------------------------------------------------------

>38417_38417_2_IFT20-SUZ12_IFT20_chr17_26656199_ENST00000395418_SUZ12_chr17_30267305_ENST00000580398_length(amino acids)=606AA_BP=
MHRTLTYMSHRNSRTNIKSLSAHLQLTFTGFFHKNDKPSPNSENEQNSVTLEVLLVKVCHKKRKDVSCPIRQVPTGKKQVPLNPDLNQTK
PGNFPSLAVSSNEFEPSNSHMVKSYSLLFRVTRPGRREFNGMINGETNENIDVNEELPARRKRNREDGEKTFVAQMTVFDKNRRLQLLDG
EYEVAMQEMEECPISKKRATWETILDGKRLPPFETFSQGPTLQFTLRWTGETNDKSTAPIAKPLATRNSESLHQENKPGSVKPTQTIAVK
ESLTTDLQTRKEKDTPNENRQKLRIFYQFLYNNNTRQQTEARDDLHCPWCTLNCRKLYSLLKHLKLCHSRFIFNYVYHPKGARIDVSINE
CYDGSYAGNPQDIHRQPGFAFSRNGPVKRTPITHILVCRPKRTKASMSEFLESEDGEVEQQRTYSSGHNRLYFHSDTCLPLRPQEMEVDS
EDEKDPEWLREKTITQIEEFSDVNEGEKEVMKLWNLHVMKHGFIADNQMNHACMLFVENYGQKIIKKNLCRNFMLHLVSMHDFNLISIMS

--------------------------------------------------------------

>38417_38417_3_IFT20-SUZ12_IFT20_chr17_26656199_ENST00000579419_SUZ12_chr17_30267305_ENST00000322652_length(amino acids)=629AA_BP=
MHRTLTYMSHRNSRTNIKRKTFKVDDMLSKVEKMKGEQESHSLSAHLQLTFTGFFHKNDKPSPNSENEQNSVTLEVLLVKVCHKKRKDVS
CPIRQVPTGKKQVPLNPDLNQTKPGNFPSLAVSSNEFEPSNSHMVKSYSLLFRVTRPGRREFNGMINGETNENIDVNEELPARRKRNRED
GEKTFVAQMTVFDKNRRLQLLDGEYEVAMQEMEECPISKKRATWETILDGKRLPPFETFSQGPTLQFTLRWTGETNDKSTAPIAKPLATR
NSESLHQENKPGSVKPTQTIAVKESLTTDLQTRKEKDTPNENRQKLRIFYQFLYNNNTRQQTEARDDLHCPWCTLNCRKLYSLLKHLKLC
HSRFIFNYVYHPKGARIDVSINECYDGSYAGNPQDIHRQPGFAFSRNGPVKRTPITHILVCRPKRTKASMSEFLESEDGEVEQQRTYSSG
HNRLYFHSDTCLPLRPQEMEVDSEDEKDPEWLREKTITQIEEFSDVNEGEKEVMKLWNLHVMKHGFIADNQMNHACMLFVENYGQKIIKK

--------------------------------------------------------------

>38417_38417_4_IFT20-SUZ12_IFT20_chr17_26656199_ENST00000579419_SUZ12_chr17_30267305_ENST00000580398_length(amino acids)=606AA_BP=
MHRTLTYMSHRNSRTNIKSLSAHLQLTFTGFFHKNDKPSPNSENEQNSVTLEVLLVKVCHKKRKDVSCPIRQVPTGKKQVPLNPDLNQTK
PGNFPSLAVSSNEFEPSNSHMVKSYSLLFRVTRPGRREFNGMINGETNENIDVNEELPARRKRNREDGEKTFVAQMTVFDKNRRLQLLDG
EYEVAMQEMEECPISKKRATWETILDGKRLPPFETFSQGPTLQFTLRWTGETNDKSTAPIAKPLATRNSESLHQENKPGSVKPTQTIAVK
ESLTTDLQTRKEKDTPNENRQKLRIFYQFLYNNNTRQQTEARDDLHCPWCTLNCRKLYSLLKHLKLCHSRFIFNYVYHPKGARIDVSINE
CYDGSYAGNPQDIHRQPGFAFSRNGPVKRTPITHILVCRPKRTKASMSEFLESEDGEVEQQRTYSSGHNRLYFHSDTCLPLRPQEMEVDS
EDEKDPEWLREKTITQIEEFSDVNEGEKEVMKLWNLHVMKHGFIADNQMNHACMLFVENYGQKIIKKNLCRNFMLHLVSMHDFNLISIMS

--------------------------------------------------------------

>38417_38417_5_IFT20-SUZ12_IFT20_chr17_26656199_ENST00000585313_SUZ12_chr17_30267305_ENST00000322652_length(amino acids)=629AA_BP=
MHRTLTYMSHRNSRTNIKRKTFKVDDMLSKVEKMKGEQESHSLSAHLQLTFTGFFHKNDKPSPNSENEQNSVTLEVLLVKVCHKKRKDVS
CPIRQVPTGKKQVPLNPDLNQTKPGNFPSLAVSSNEFEPSNSHMVKSYSLLFRVTRPGRREFNGMINGETNENIDVNEELPARRKRNRED
GEKTFVAQMTVFDKNRRLQLLDGEYEVAMQEMEECPISKKRATWETILDGKRLPPFETFSQGPTLQFTLRWTGETNDKSTAPIAKPLATR
NSESLHQENKPGSVKPTQTIAVKESLTTDLQTRKEKDTPNENRQKLRIFYQFLYNNNTRQQTEARDDLHCPWCTLNCRKLYSLLKHLKLC
HSRFIFNYVYHPKGARIDVSINECYDGSYAGNPQDIHRQPGFAFSRNGPVKRTPITHILVCRPKRTKASMSEFLESEDGEVEQQRTYSSG
HNRLYFHSDTCLPLRPQEMEVDSEDEKDPEWLREKTITQIEEFSDVNEGEKEVMKLWNLHVMKHGFIADNQMNHACMLFVENYGQKIIKK

--------------------------------------------------------------

>38417_38417_6_IFT20-SUZ12_IFT20_chr17_26656199_ENST00000585313_SUZ12_chr17_30267305_ENST00000580398_length(amino acids)=606AA_BP=
MHRTLTYMSHRNSRTNIKSLSAHLQLTFTGFFHKNDKPSPNSENEQNSVTLEVLLVKVCHKKRKDVSCPIRQVPTGKKQVPLNPDLNQTK
PGNFPSLAVSSNEFEPSNSHMVKSYSLLFRVTRPGRREFNGMINGETNENIDVNEELPARRKRNREDGEKTFVAQMTVFDKNRRLQLLDG
EYEVAMQEMEECPISKKRATWETILDGKRLPPFETFSQGPTLQFTLRWTGETNDKSTAPIAKPLATRNSESLHQENKPGSVKPTQTIAVK
ESLTTDLQTRKEKDTPNENRQKLRIFYQFLYNNNTRQQTEARDDLHCPWCTLNCRKLYSLLKHLKLCHSRFIFNYVYHPKGARIDVSINE
CYDGSYAGNPQDIHRQPGFAFSRNGPVKRTPITHILVCRPKRTKASMSEFLESEDGEVEQQRTYSSGHNRLYFHSDTCLPLRPQEMEVDS
EDEKDPEWLREKTITQIEEFSDVNEGEKEVMKLWNLHVMKHGFIADNQMNHACMLFVENYGQKIIKKNLCRNFMLHLVSMHDFNLISIMS

--------------------------------------------------------------

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Fusion Protein Functional Features

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr17:26656199/chr17:30267305)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
IFT20 Q8IY31	SUZ12 Q15022
FUNCTION: Part of intraflagellar transport (IFT) particles involved in ciliary process assembly. May play a role in the trafficking of ciliary membrane proteins from the Golgi complex to the cilium (PubMed:16775004). Regulates the platelet-derived growth factor receptor-alpha (PDGFRA) signaling pathway. Required for protein stability of E3 ubiquitin ligases CBL and CBLB that mediate ubiquitination and internalization of PDGFRA for proper feedback inhibition of PDGFRA signaling (PubMed:29237719). Essential for male fertility. Plays an important role in spermatogenesis, particularly spermiogenesis, when germ cells form flagella. May play a role in the transport of flagellar proteins ODF2 and SPAG16 to build sperm flagella and in the removal of redundant sperm cytoplasm (By similarity). Also involved in autophagy since it is required for trafficking of ATG16L and the expansion of the autophagic compartment (By similarity). {ECO:0000250\|UniProtKB:Q61025, ECO:0000269\|PubMed:16775004, ECO:0000269\|PubMed:29237719}.	FUNCTION: Polycomb group (PcG) protein. Component of the PRC2 complex, which methylates 'Lys-9' (H3K9me) and 'Lys-27' (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene (PubMed:15225548, PubMed:15231737, PubMed:15385962, PubMed:16618801, PubMed:17344414, PubMed:18285464, PubMed:28229514, PubMed:29499137, PubMed:31959557). The PRC2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems (PubMed:12435631, PubMed:12351676, PubMed:15385962, PubMed:15099518, PubMed:15225548, PubMed:15684044, PubMed:16431907, PubMed:18086877, PubMed:18285464). Genes repressed by the PRC2 complex include HOXC8, HOXA9, MYT1 and CDKN2A (PubMed:15231737, PubMed:16618801, PubMed:17200670, PubMed:31959557). {ECO:0000269\|PubMed:12351676, ECO:0000269\|PubMed:12435631, ECO:0000269\|PubMed:15099518, ECO:0000269\|PubMed:15225548, ECO:0000269\|PubMed:15231737, ECO:0000269\|PubMed:15385962, ECO:0000269\|PubMed:15684044, ECO:0000269\|PubMed:16431907, ECO:0000269\|PubMed:16618801, ECO:0000269\|PubMed:17200670, ECO:0000269\|PubMed:17344414, ECO:0000269\|PubMed:18086877, ECO:0000269\|PubMed:18285464, ECO:0000269\|PubMed:28229514, ECO:0000269\|PubMed:29499137, ECO:0000269\|PubMed:31959557}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page
* Minus value of BPloci means that the break pointn is located before the CDS.

- Retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

IFT20

chr17:26656199

chr17:30267305

ENST00000357896

74_114

145.0

149.0

Coiled coil

Ontology_term=ECO:0000255

Hgene

IFT20

chr17:26656199

chr17:30267305

ENST00000585089

74_114

131.66666666666666

159.0

Coiled coil

Ontology_term=ECO:0000255

Hgene

IFT20

chr17:26656199

chr17:30267305

ENST00000357896

70_132

145.0

149.0

Region

IFT57-binding

Hgene

IFT20

chr17:26656199

chr17:30267305

ENST00000585089

70_132

131.66666666666666

159.0

Region

IFT57-binding

Tgene

SUZ12

chr17:26656199

chr17:30267305

ENST00000322652

563_639

91.33333333333333

740.0

Region

Note=VEFS-box

Tgene

SUZ12

chr17:26656199

chr17:30267305

ENST00000322652

448_471

91.33333333333333

740.0

Zinc finger

Note=C2H2-type

- Not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

IFT20

chr17:26656199

chr17:30267305

ENST00000395418

74_114

105.66666666666667

133.0

Coiled coil

Ontology_term=ECO:0000255

Hgene

IFT20

chr17:26656199

chr17:30267305

ENST00000579419

74_114

105.66666666666667

115.0

Coiled coil

Ontology_term=ECO:0000255

Hgene

IFT20

chr17:26656199

chr17:30267305

ENST00000585313

74_114

105.66666666666667

133.0

Coiled coil

Ontology_term=ECO:0000255

Hgene

IFT20

chr17:26656199

chr17:30267305

ENST00000395418

70_132

105.66666666666667

133.0

Region

IFT57-binding

Hgene

IFT20

chr17:26656199

chr17:30267305

ENST00000579419

70_132

105.66666666666667

115.0

Region

IFT57-binding

Hgene

IFT20

chr17:26656199

chr17:30267305

ENST00000585313

70_132

105.66666666666667

133.0

Region

IFT57-binding

Tgene

SUZ12

chr17:26656199

chr17:30267305

ENST00000322652

51_59

91.33333333333333

740.0

Compositional bias

Note=Poly-Ser

Tgene

SUZ12

chr17:26656199

chr17:30267305

ENST00000322652

60_67

91.33333333333333

740.0

Compositional bias

Note=Poly-Ala

Tgene

SUZ12

chr17:26656199

chr17:30267305

ENST00000322652

7_50

91.33333333333333

740.0

Compositional bias

Note=Gly-rich

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Fusion Protein-Protein Interaction

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type from validated records (BIOGRID-3.4.160)

Gene

PPI interactors

Protein-protein interactors based on sequence similarity (STRING)

Gene	STRING network
IFT20
SUZ12

- Retained interactions in fusion protein (protein functional feature from UniProt).

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost interactions due to fusion (protein functional feature from UniProt).

Partner	Gene	Hbp	Tbp	ENST	Strand	BPexon	TotalExon	Protein feature loci	*BPloci	TotalLen	Interaction lost with
Tgene	SUZ12	chr17:26656199	chr17:30267305	ENST00000322652		0	16	79_106	91.33333333333333	740.0	JARID2 and EPOP

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Related Drugs to IFT20-SUZ12

Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)

Hgene

Tgene

Drug

Source

PMID

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Related Diseases to IFT20-SUZ12

Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)

Hgene

Tgene

Disease

Source

PMID

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner	Gene	Disease ID	Disease name	# pubmeds	Source
Tgene	SUZ12	C0206727	Nerve Sheath Tumors	2	CTD_human
Tgene	SUZ12	C0751689	Peripheral Nerve Sheath Neoplasm	2	CTD_human
Tgene	SUZ12	C0751691	Perineurioma	2	CTD_human
Tgene	SUZ12	C0001430	Adenoma	1	CTD_human
Tgene	SUZ12	C0014170	Endometrial Neoplasms	1	CTD_human
Tgene	SUZ12	C0017636	Glioblastoma	1	CTD_human
Tgene	SUZ12	C0017638	Glioma	1	CTD_human
Tgene	SUZ12	C0025202	melanoma	1	CTD_human
Tgene	SUZ12	C0027809	Neurilemmoma	1	CTD_human
Tgene	SUZ12	C0027830	neurofibroma	1	CTD_human
Tgene	SUZ12	C0027962	Melanocytic nevus	1	CTD_human
Tgene	SUZ12	C0042063	Urogenital Abnormalities	1	GENOMICS_ENGLAND
Tgene	SUZ12	C0205646	Adenoma, Basal Cell	1	CTD_human
Tgene	SUZ12	C0205647	Follicular adenoma	1	CTD_human
Tgene	SUZ12	C0205648	Adenoma, Microcystic	1	CTD_human
Tgene	SUZ12	C0205649	Adenoma, Monomorphic	1	CTD_human
Tgene	SUZ12	C0205650	Papillary adenoma	1	CTD_human
Tgene	SUZ12	C0205651	Adenoma, Trabecular	1	CTD_human
Tgene	SUZ12	C0206630	Endometrial Stromal Sarcoma	1	ORPHANET
Tgene	SUZ12	C0259783	mixed gliomas	1	CTD_human
Tgene	SUZ12	C0265210	Weaver syndrome	1	ORPHANET
Tgene	SUZ12	C0334588	Giant Cell Glioblastoma	1	CTD_human
Tgene	SUZ12	C0476089	Endometrial Carcinoma	1	CTD_human
Tgene	SUZ12	C0545053	Advanced bone age	1	GENOMICS_ENGLAND
Tgene	SUZ12	C0555198	Malignant Glioma	1	CTD_human
Tgene	SUZ12	C0557874	Global developmental delay	1	GENOMICS_ENGLAND
Tgene	SUZ12	C0751374	Schwannomatosis, Plexiform	1	CTD_human
Tgene	SUZ12	C1621958	Glioblastoma Multiforme	1	CTD_human
Tgene	SUZ12	C1842581	Abnormal corpus callosum morphology	1	GENOMICS_ENGLAND
Tgene	SUZ12	C1849265	Overgrowth	1	GENOMICS_ENGLAND
Tgene	SUZ12	C3714756	Intellectual Disability	1	GENOMICS_ENGLAND
Tgene	SUZ12	C4018871	Abnormality of the respiratory system	1	GENOMICS_ENGLAND
Tgene	SUZ12	C4021664	Abnormality of the abdominal wall	1	GENOMICS_ENGLAND
Tgene	SUZ12	C4021790	Abnormality of the skeletal system	1	GENOMICS_ENGLAND