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	Fusion Gene Summary
	Fusion Gene Sample Information
	Fusion ORF Analysis
	Fusion Amino Acid Sequences
	Fusion Protein Functional Features
	Fusion Protein-Protein Interaction
	Related drugs with this fusion protein
	Related disease with this fusion protein

Fusion Protein:IKZF3-SMARCE1

Fusion Protein Summary

Fusion gene summary

Fusion partner gene information	Fusion gene name: IKZF3-SMARCE1
	FusionPDB ID: 39409
	FusionGDB2.0 ID: 39409
		Hgene	Tgene
	Gene symbol	IKZF3	SMARCE1
	Gene ID	22806	6605
	Gene name	IKAROS family zinc finger 3	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
	Synonyms	AIO\|AIOLOS\|ZNFN1A3	BAF57\|CSS5
	Cytomap	17q12-q21.1	17q21.2
	Type of gene	protein-coding	protein-coding
	Description	zinc finger protein Aioloszinc finger DNA binding protein Aioloszinc finger protein, subfamily 1A, 3 (Aiolos)	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1BRG1-associated factor 57SWI/SNF-related matrix-associated actin-dependent regulator of chromatin e1chromatin remodeling complex BRG1-associated factor 57
	Modification date	20200327	20200313
	UniProtAcc	Q9UKT9	.
Ensembl transtripts involved in fusion gene	ENST ids	ENST00000346243, ENST00000346872, ENST00000350532, ENST00000351680, ENST00000377944, ENST00000377945, ENST00000377952, ENST00000377958, ENST00000394189, ENST00000439016, ENST00000467757, ENST00000439167, ENST00000535189, ENST00000583368,	ENST00000474246, ENST00000348513, ENST00000377808, ENST00000400122, ENST00000431889, ENST00000544009, ENST00000578044, ENST00000580419,
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)	* DoF score	10 X 9 X 7=630	10 X 11 X 5=550
	# samples	11	12
	** MAII score	log2(11/630*10)=-2.51784830486262 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(12/550*10)=-2.1963972128035 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context (manual curation of fusion genes in FusionPDB)	PubMed: IKZF3 [Title/Abstract] AND SMARCE1 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)	IKZF3(37985639)-SMARCE1(38788619), # samples:1
Anticipated loss of major functional domain due to fusion event.	IKZF3-SMARCE1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. IKZF3-SMARCE1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. IKZF3-SMARCE1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. IKZF3-SMARCE1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Tgene	SMARCE1	GO:0006337	nucleosome disassembly	8895581
Tgene	SMARCE1	GO:0006338	chromatin remodeling	11726552
Tgene	SMARCE1	GO:0045892	negative regulation of transcription, DNA-templated	12192000

Fusion gene breakpoints across IKZF3 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across SMARCE1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

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Fusion Gene Sample Information

Fusion gene information from FusionGDB2.0.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	READ	TCGA-EI-6509	IKZF3	chr17	37985639	-	SMARCE1	chr17	38788619	-

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Fusion ORF Analysis

Fusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000346872	IKZF3	chr17	37985639	-	ENST00000348513	SMARCE1	chr17	38788619	-	4743	225	62	919	285
ENST00000346872	IKZF3	chr17	37985639	-	ENST00000544009	SMARCE1	chr17	38788619	-	1431	225	62	919	285
ENST00000346872	IKZF3	chr17	37985639	-	ENST00000431889	SMARCE1	chr17	38788619	-	1237	225	62	919	285
ENST00000346872	IKZF3	chr17	37985639	-	ENST00000580419	SMARCE1	chr17	38788619	-	926	225	62	919	285
ENST00000346872	IKZF3	chr17	37985639	-	ENST00000377808	SMARCE1	chr17	38788619	-	1005	225	62	775	237
ENST00000346872	IKZF3	chr17	37985639	-	ENST00000400122	SMARCE1	chr17	38788619	-	1005	225	62	775	237
ENST00000346872	IKZF3	chr17	37985639	-	ENST00000578044	SMARCE1	chr17	38788619	-	926	225	62	919	285
ENST00000394189	IKZF3	chr17	37985639	-	ENST00000348513	SMARCE1	chr17	38788619	-	4743	225	62	919	285
ENST00000394189	IKZF3	chr17	37985639	-	ENST00000544009	SMARCE1	chr17	38788619	-	1431	225	62	919	285
ENST00000394189	IKZF3	chr17	37985639	-	ENST00000431889	SMARCE1	chr17	38788619	-	1237	225	62	919	285
ENST00000394189	IKZF3	chr17	37985639	-	ENST00000580419	SMARCE1	chr17	38788619	-	926	225	62	919	285
ENST00000394189	IKZF3	chr17	37985639	-	ENST00000377808	SMARCE1	chr17	38788619	-	1005	225	62	775	237
ENST00000394189	IKZF3	chr17	37985639	-	ENST00000400122	SMARCE1	chr17	38788619	-	1005	225	62	775	237
ENST00000394189	IKZF3	chr17	37985639	-	ENST00000578044	SMARCE1	chr17	38788619	-	926	225	62	919	285
ENST00000377944	IKZF3	chr17	37985639	-	ENST00000348513	SMARCE1	chr17	38788619	-	4743	225	62	919	285
ENST00000377944	IKZF3	chr17	37985639	-	ENST00000544009	SMARCE1	chr17	38788619	-	1431	225	62	919	285
ENST00000377944	IKZF3	chr17	37985639	-	ENST00000431889	SMARCE1	chr17	38788619	-	1237	225	62	919	285
ENST00000377944	IKZF3	chr17	37985639	-	ENST00000580419	SMARCE1	chr17	38788619	-	926	225	62	919	285
ENST00000377944	IKZF3	chr17	37985639	-	ENST00000377808	SMARCE1	chr17	38788619	-	1005	225	62	775	237
ENST00000377944	IKZF3	chr17	37985639	-	ENST00000400122	SMARCE1	chr17	38788619	-	1005	225	62	775	237
ENST00000377944	IKZF3	chr17	37985639	-	ENST00000578044	SMARCE1	chr17	38788619	-	926	225	62	919	285
ENST00000377945	IKZF3	chr17	37985639	-	ENST00000348513	SMARCE1	chr17	38788619	-	4743	225	62	919	285
ENST00000377945	IKZF3	chr17	37985639	-	ENST00000544009	SMARCE1	chr17	38788619	-	1431	225	62	919	285
ENST00000377945	IKZF3	chr17	37985639	-	ENST00000431889	SMARCE1	chr17	38788619	-	1237	225	62	919	285
ENST00000377945	IKZF3	chr17	37985639	-	ENST00000580419	SMARCE1	chr17	38788619	-	926	225	62	919	285
ENST00000377945	IKZF3	chr17	37985639	-	ENST00000377808	SMARCE1	chr17	38788619	-	1005	225	62	775	237
ENST00000377945	IKZF3	chr17	37985639	-	ENST00000400122	SMARCE1	chr17	38788619	-	1005	225	62	775	237
ENST00000377945	IKZF3	chr17	37985639	-	ENST00000578044	SMARCE1	chr17	38788619	-	926	225	62	919	285
ENST00000377952	IKZF3	chr17	37985639	-	ENST00000348513	SMARCE1	chr17	38788619	-	4743	225	62	919	285
ENST00000377952	IKZF3	chr17	37985639	-	ENST00000544009	SMARCE1	chr17	38788619	-	1431	225	62	919	285
ENST00000377952	IKZF3	chr17	37985639	-	ENST00000431889	SMARCE1	chr17	38788619	-	1237	225	62	919	285
ENST00000377952	IKZF3	chr17	37985639	-	ENST00000580419	SMARCE1	chr17	38788619	-	926	225	62	919	285
ENST00000377952	IKZF3	chr17	37985639	-	ENST00000377808	SMARCE1	chr17	38788619	-	1005	225	62	775	237
ENST00000377952	IKZF3	chr17	37985639	-	ENST00000400122	SMARCE1	chr17	38788619	-	1005	225	62	775	237
ENST00000377952	IKZF3	chr17	37985639	-	ENST00000578044	SMARCE1	chr17	38788619	-	926	225	62	919	285
ENST00000377958	IKZF3	chr17	37985639	-	ENST00000348513	SMARCE1	chr17	38788619	-	4743	225	62	919	285
ENST00000377958	IKZF3	chr17	37985639	-	ENST00000544009	SMARCE1	chr17	38788619	-	1431	225	62	919	285
ENST00000377958	IKZF3	chr17	37985639	-	ENST00000431889	SMARCE1	chr17	38788619	-	1237	225	62	919	285
ENST00000377958	IKZF3	chr17	37985639	-	ENST00000580419	SMARCE1	chr17	38788619	-	926	225	62	919	285
ENST00000377958	IKZF3	chr17	37985639	-	ENST00000377808	SMARCE1	chr17	38788619	-	1005	225	62	775	237
ENST00000377958	IKZF3	chr17	37985639	-	ENST00000400122	SMARCE1	chr17	38788619	-	1005	225	62	775	237
ENST00000377958	IKZF3	chr17	37985639	-	ENST00000578044	SMARCE1	chr17	38788619	-	926	225	62	919	285
ENST00000346243	IKZF3	chr17	37985639	-	ENST00000348513	SMARCE1	chr17	38788619	-	4681	163	0	857	285
ENST00000346243	IKZF3	chr17	37985639	-	ENST00000544009	SMARCE1	chr17	38788619	-	1369	163	0	857	285
ENST00000346243	IKZF3	chr17	37985639	-	ENST00000431889	SMARCE1	chr17	38788619	-	1175	163	0	857	285
ENST00000346243	IKZF3	chr17	37985639	-	ENST00000580419	SMARCE1	chr17	38788619	-	864	163	0	857	285
ENST00000346243	IKZF3	chr17	37985639	-	ENST00000377808	SMARCE1	chr17	38788619	-	943	163	0	713	237
ENST00000346243	IKZF3	chr17	37985639	-	ENST00000400122	SMARCE1	chr17	38788619	-	943	163	0	713	237
ENST00000346243	IKZF3	chr17	37985639	-	ENST00000578044	SMARCE1	chr17	38788619	-	864	163	0	857	285
ENST00000350532	IKZF3	chr17	37985639	-	ENST00000348513	SMARCE1	chr17	38788619	-	4681	163	0	857	285
ENST00000350532	IKZF3	chr17	37985639	-	ENST00000544009	SMARCE1	chr17	38788619	-	1369	163	0	857	285
ENST00000350532	IKZF3	chr17	37985639	-	ENST00000431889	SMARCE1	chr17	38788619	-	1175	163	0	857	285
ENST00000350532	IKZF3	chr17	37985639	-	ENST00000580419	SMARCE1	chr17	38788619	-	864	163	0	857	285
ENST00000350532	IKZF3	chr17	37985639	-	ENST00000377808	SMARCE1	chr17	38788619	-	943	163	0	713	237
ENST00000350532	IKZF3	chr17	37985639	-	ENST00000400122	SMARCE1	chr17	38788619	-	943	163	0	713	237
ENST00000350532	IKZF3	chr17	37985639	-	ENST00000578044	SMARCE1	chr17	38788619	-	864	163	0	857	285
ENST00000351680	IKZF3	chr17	37985639	-	ENST00000348513	SMARCE1	chr17	38788619	-	4681	163	0	857	285
ENST00000351680	IKZF3	chr17	37985639	-	ENST00000544009	SMARCE1	chr17	38788619	-	1369	163	0	857	285
ENST00000351680	IKZF3	chr17	37985639	-	ENST00000431889	SMARCE1	chr17	38788619	-	1175	163	0	857	285
ENST00000351680	IKZF3	chr17	37985639	-	ENST00000580419	SMARCE1	chr17	38788619	-	864	163	0	857	285
ENST00000351680	IKZF3	chr17	37985639	-	ENST00000377808	SMARCE1	chr17	38788619	-	943	163	0	713	237
ENST00000351680	IKZF3	chr17	37985639	-	ENST00000400122	SMARCE1	chr17	38788619	-	943	163	0	713	237
ENST00000351680	IKZF3	chr17	37985639	-	ENST00000578044	SMARCE1	chr17	38788619	-	864	163	0	857	285
ENST00000467757	IKZF3	chr17	37985639	-	ENST00000348513	SMARCE1	chr17	38788619	-	4681	163	0	857	285
ENST00000467757	IKZF3	chr17	37985639	-	ENST00000544009	SMARCE1	chr17	38788619	-	1369	163	0	857	285
ENST00000467757	IKZF3	chr17	37985639	-	ENST00000431889	SMARCE1	chr17	38788619	-	1175	163	0	857	285
ENST00000467757	IKZF3	chr17	37985639	-	ENST00000580419	SMARCE1	chr17	38788619	-	864	163	0	857	285
ENST00000467757	IKZF3	chr17	37985639	-	ENST00000377808	SMARCE1	chr17	38788619	-	943	163	0	713	237
ENST00000467757	IKZF3	chr17	37985639	-	ENST00000400122	SMARCE1	chr17	38788619	-	943	163	0	713	237
ENST00000467757	IKZF3	chr17	37985639	-	ENST00000578044	SMARCE1	chr17	38788619	-	864	163	0	857	285
ENST00000439016	IKZF3	chr17	37985639	-	ENST00000348513	SMARCE1	chr17	38788619	-	4682	164	1	858	285
ENST00000439016	IKZF3	chr17	37985639	-	ENST00000544009	SMARCE1	chr17	38788619	-	1370	164	1	858	285
ENST00000439016	IKZF3	chr17	37985639	-	ENST00000431889	SMARCE1	chr17	38788619	-	1176	164	1	858	285
ENST00000439016	IKZF3	chr17	37985639	-	ENST00000580419	SMARCE1	chr17	38788619	-	865	164	1	858	285
ENST00000439016	IKZF3	chr17	37985639	-	ENST00000377808	SMARCE1	chr17	38788619	-	944	164	1	714	237
ENST00000439016	IKZF3	chr17	37985639	-	ENST00000400122	SMARCE1	chr17	38788619	-	944	164	1	714	237
ENST00000439016	IKZF3	chr17	37985639	-	ENST00000578044	SMARCE1	chr17	38788619	-	865	164	1	858	285

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000346872	ENST00000348513	IKZF3	chr17	37985639	-	SMARCE1	chr17	38788619	-	0.000325999	0.99967396
ENST00000346872	ENST00000544009	IKZF3	chr17	37985639	-	SMARCE1	chr17	38788619	-	0.001016976	0.99898297
ENST00000346872	ENST00000431889	IKZF3	chr17	37985639	-	SMARCE1	chr17	38788619	-	0.001962034	0.998038
ENST00000346872	ENST00000580419	IKZF3	chr17	37985639	-	SMARCE1	chr17	38788619	-	0.004103309	0.9958967
ENST00000346872	ENST00000377808	IKZF3	chr17	37985639	-	SMARCE1	chr17	38788619	-	0.005134211	0.99486583
ENST00000346872	ENST00000400122	IKZF3	chr17	37985639	-	SMARCE1	chr17	38788619	-	0.005134211	0.99486583
ENST00000346872	ENST00000578044	IKZF3	chr17	37985639	-	SMARCE1	chr17	38788619	-	0.004103309	0.9958967
ENST00000394189	ENST00000348513	IKZF3	chr17	37985639	-	SMARCE1	chr17	38788619	-	0.000325999	0.99967396
ENST00000394189	ENST00000544009	IKZF3	chr17	37985639	-	SMARCE1	chr17	38788619	-	0.001016976	0.99898297
ENST00000394189	ENST00000431889	IKZF3	chr17	37985639	-	SMARCE1	chr17	38788619	-	0.001962034	0.998038
ENST00000394189	ENST00000580419	IKZF3	chr17	37985639	-	SMARCE1	chr17	38788619	-	0.004103309	0.9958967
ENST00000394189	ENST00000377808	IKZF3	chr17	37985639	-	SMARCE1	chr17	38788619	-	0.005134211	0.99486583
ENST00000394189	ENST00000400122	IKZF3	chr17	37985639	-	SMARCE1	chr17	38788619	-	0.005134211	0.99486583
ENST00000394189	ENST00000578044	IKZF3	chr17	37985639	-	SMARCE1	chr17	38788619	-	0.004103309	0.9958967
ENST00000377944	ENST00000348513	IKZF3	chr17	37985639	-	SMARCE1	chr17	38788619	-	0.000325999	0.99967396
ENST00000377944	ENST00000544009	IKZF3	chr17	37985639	-	SMARCE1	chr17	38788619	-	0.001016976	0.99898297
ENST00000377944	ENST00000431889	IKZF3	chr17	37985639	-	SMARCE1	chr17	38788619	-	0.001962034	0.998038
ENST00000377944	ENST00000580419	IKZF3	chr17	37985639	-	SMARCE1	chr17	38788619	-	0.004103309	0.9958967
ENST00000377944	ENST00000377808	IKZF3	chr17	37985639	-	SMARCE1	chr17	38788619	-	0.005134211	0.99486583
ENST00000377944	ENST00000400122	IKZF3	chr17	37985639	-	SMARCE1	chr17	38788619	-	0.005134211	0.99486583
ENST00000377944	ENST00000578044	IKZF3	chr17	37985639	-	SMARCE1	chr17	38788619	-	0.004103309	0.9958967
ENST00000377945	ENST00000348513	IKZF3	chr17	37985639	-	SMARCE1	chr17	38788619	-	0.000325999	0.99967396
ENST00000377945	ENST00000544009	IKZF3	chr17	37985639	-	SMARCE1	chr17	38788619	-	0.001016976	0.99898297
ENST00000377945	ENST00000431889	IKZF3	chr17	37985639	-	SMARCE1	chr17	38788619	-	0.001962034	0.998038
ENST00000377945	ENST00000580419	IKZF3	chr17	37985639	-	SMARCE1	chr17	38788619	-	0.004103309	0.9958967
ENST00000377945	ENST00000377808	IKZF3	chr17	37985639	-	SMARCE1	chr17	38788619	-	0.005134211	0.99486583
ENST00000377945	ENST00000400122	IKZF3	chr17	37985639	-	SMARCE1	chr17	38788619	-	0.005134211	0.99486583
ENST00000377945	ENST00000578044	IKZF3	chr17	37985639	-	SMARCE1	chr17	38788619	-	0.004103309	0.9958967
ENST00000377952	ENST00000348513	IKZF3	chr17	37985639	-	SMARCE1	chr17	38788619	-	0.000325999	0.99967396
ENST00000377952	ENST00000544009	IKZF3	chr17	37985639	-	SMARCE1	chr17	38788619	-	0.001016976	0.99898297
ENST00000377952	ENST00000431889	IKZF3	chr17	37985639	-	SMARCE1	chr17	38788619	-	0.001962034	0.998038
ENST00000377952	ENST00000580419	IKZF3	chr17	37985639	-	SMARCE1	chr17	38788619	-	0.004103309	0.9958967
ENST00000377952	ENST00000377808	IKZF3	chr17	37985639	-	SMARCE1	chr17	38788619	-	0.005134211	0.99486583
ENST00000377952	ENST00000400122	IKZF3	chr17	37985639	-	SMARCE1	chr17	38788619	-	0.005134211	0.99486583
ENST00000377952	ENST00000578044	IKZF3	chr17	37985639	-	SMARCE1	chr17	38788619	-	0.004103309	0.9958967
ENST00000377958	ENST00000348513	IKZF3	chr17	37985639	-	SMARCE1	chr17	38788619	-	0.000325999	0.99967396
ENST00000377958	ENST00000544009	IKZF3	chr17	37985639	-	SMARCE1	chr17	38788619	-	0.001016976	0.99898297
ENST00000377958	ENST00000431889	IKZF3	chr17	37985639	-	SMARCE1	chr17	38788619	-	0.001962034	0.998038
ENST00000377958	ENST00000580419	IKZF3	chr17	37985639	-	SMARCE1	chr17	38788619	-	0.004103309	0.9958967
ENST00000377958	ENST00000377808	IKZF3	chr17	37985639	-	SMARCE1	chr17	38788619	-	0.005134211	0.99486583
ENST00000377958	ENST00000400122	IKZF3	chr17	37985639	-	SMARCE1	chr17	38788619	-	0.005134211	0.99486583
ENST00000377958	ENST00000578044	IKZF3	chr17	37985639	-	SMARCE1	chr17	38788619	-	0.004103309	0.9958967
ENST00000346243	ENST00000348513	IKZF3	chr17	37985639	-	SMARCE1	chr17	38788619	-	0.000315783	0.9996842
ENST00000346243	ENST00000544009	IKZF3	chr17	37985639	-	SMARCE1	chr17	38788619	-	0.000874758	0.9991253
ENST00000346243	ENST00000431889	IKZF3	chr17	37985639	-	SMARCE1	chr17	38788619	-	0.001782304	0.99821764
ENST00000346243	ENST00000580419	IKZF3	chr17	37985639	-	SMARCE1	chr17	38788619	-	0.00619586	0.9938041
ENST00000346243	ENST00000377808	IKZF3	chr17	37985639	-	SMARCE1	chr17	38788619	-	0.00726349	0.9927366
ENST00000346243	ENST00000400122	IKZF3	chr17	37985639	-	SMARCE1	chr17	38788619	-	0.00726349	0.9927366
ENST00000346243	ENST00000578044	IKZF3	chr17	37985639	-	SMARCE1	chr17	38788619	-	0.00619586	0.9938041
ENST00000350532	ENST00000348513	IKZF3	chr17	37985639	-	SMARCE1	chr17	38788619	-	0.000315783	0.9996842
ENST00000350532	ENST00000544009	IKZF3	chr17	37985639	-	SMARCE1	chr17	38788619	-	0.000874758	0.9991253
ENST00000350532	ENST00000431889	IKZF3	chr17	37985639	-	SMARCE1	chr17	38788619	-	0.001782304	0.99821764
ENST00000350532	ENST00000580419	IKZF3	chr17	37985639	-	SMARCE1	chr17	38788619	-	0.00619586	0.9938041
ENST00000350532	ENST00000377808	IKZF3	chr17	37985639	-	SMARCE1	chr17	38788619	-	0.00726349	0.9927366
ENST00000350532	ENST00000400122	IKZF3	chr17	37985639	-	SMARCE1	chr17	38788619	-	0.00726349	0.9927366
ENST00000350532	ENST00000578044	IKZF3	chr17	37985639	-	SMARCE1	chr17	38788619	-	0.00619586	0.9938041
ENST00000351680	ENST00000348513	IKZF3	chr17	37985639	-	SMARCE1	chr17	38788619	-	0.000315783	0.9996842
ENST00000351680	ENST00000544009	IKZF3	chr17	37985639	-	SMARCE1	chr17	38788619	-	0.000874758	0.9991253
ENST00000351680	ENST00000431889	IKZF3	chr17	37985639	-	SMARCE1	chr17	38788619	-	0.001782304	0.99821764
ENST00000351680	ENST00000580419	IKZF3	chr17	37985639	-	SMARCE1	chr17	38788619	-	0.00619586	0.9938041
ENST00000351680	ENST00000377808	IKZF3	chr17	37985639	-	SMARCE1	chr17	38788619	-	0.00726349	0.9927366
ENST00000351680	ENST00000400122	IKZF3	chr17	37985639	-	SMARCE1	chr17	38788619	-	0.00726349	0.9927366
ENST00000351680	ENST00000578044	IKZF3	chr17	37985639	-	SMARCE1	chr17	38788619	-	0.00619586	0.9938041
ENST00000467757	ENST00000348513	IKZF3	chr17	37985639	-	SMARCE1	chr17	38788619	-	0.000315783	0.9996842
ENST00000467757	ENST00000544009	IKZF3	chr17	37985639	-	SMARCE1	chr17	38788619	-	0.000874758	0.9991253
ENST00000467757	ENST00000431889	IKZF3	chr17	37985639	-	SMARCE1	chr17	38788619	-	0.001782304	0.99821764
ENST00000467757	ENST00000580419	IKZF3	chr17	37985639	-	SMARCE1	chr17	38788619	-	0.00619586	0.9938041
ENST00000467757	ENST00000377808	IKZF3	chr17	37985639	-	SMARCE1	chr17	38788619	-	0.00726349	0.9927366
ENST00000467757	ENST00000400122	IKZF3	chr17	37985639	-	SMARCE1	chr17	38788619	-	0.00726349	0.9927366
ENST00000467757	ENST00000578044	IKZF3	chr17	37985639	-	SMARCE1	chr17	38788619	-	0.00619586	0.9938041
ENST00000439016	ENST00000348513	IKZF3	chr17	37985639	-	SMARCE1	chr17	38788619	-	0.000314465	0.9996855
ENST00000439016	ENST00000544009	IKZF3	chr17	37985639	-	SMARCE1	chr17	38788619	-	0.000866321	0.99913365
ENST00000439016	ENST00000431889	IKZF3	chr17	37985639	-	SMARCE1	chr17	38788619	-	0.001772304	0.99822766
ENST00000439016	ENST00000580419	IKZF3	chr17	37985639	-	SMARCE1	chr17	38788619	-	0.006012401	0.99398756
ENST00000439016	ENST00000377808	IKZF3	chr17	37985639	-	SMARCE1	chr17	38788619	-	0.007056655	0.99294335
ENST00000439016	ENST00000400122	IKZF3	chr17	37985639	-	SMARCE1	chr17	38788619	-	0.007056655	0.99294335
ENST00000439016	ENST00000578044	IKZF3	chr17	37985639	-	SMARCE1	chr17	38788619	-	0.006012401	0.99398756

Top

Fusion Amino Acid Sequences

For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

>39409_39409_1_IKZF3-SMARCE1_IKZF3_chr17_37985639_ENST00000346243_SMARCE1_chr17_38788619_ENST00000348513_length(amino acids)=285AA_BP=54
MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVR
SVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKE
AAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTESQQNGEEGTSTPEDKESGQEGVDSMAEEGTSDSNTGSESNSATV

--------------------------------------------------------------

>39409_39409_2_IKZF3-SMARCE1_IKZF3_chr17_37985639_ENST00000346243_SMARCE1_chr17_38788619_ENST00000377808_length(amino acids)=237AA_BP=54
MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVR
SVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKE

--------------------------------------------------------------

>39409_39409_3_IKZF3-SMARCE1_IKZF3_chr17_37985639_ENST00000346243_SMARCE1_chr17_38788619_ENST00000400122_length(amino acids)=237AA_BP=54
MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVR
SVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKE

--------------------------------------------------------------

>39409_39409_4_IKZF3-SMARCE1_IKZF3_chr17_37985639_ENST00000346243_SMARCE1_chr17_38788619_ENST00000431889_length(amino acids)=285AA_BP=54
MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVR
SVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKE
AAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTESQQNGEEGTSTPEDKESGQEGVDSMAEEGTSDSNTGSESNSATV

--------------------------------------------------------------

>39409_39409_5_IKZF3-SMARCE1_IKZF3_chr17_37985639_ENST00000346243_SMARCE1_chr17_38788619_ENST00000544009_length(amino acids)=285AA_BP=54
MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVR
SVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKE
AAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTESQQNGEEGTSTPEDKESGQEGVDSMAEEGTSDSNTGSESNSATV

--------------------------------------------------------------

>39409_39409_6_IKZF3-SMARCE1_IKZF3_chr17_37985639_ENST00000346243_SMARCE1_chr17_38788619_ENST00000578044_length(amino acids)=285AA_BP=54
MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVR
SVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKE
AAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTESQQNGEEGTSTPEDKESGQEGVDSMAEEGTSDSNTGSESNSATV

--------------------------------------------------------------

>39409_39409_7_IKZF3-SMARCE1_IKZF3_chr17_37985639_ENST00000346243_SMARCE1_chr17_38788619_ENST00000580419_length(amino acids)=285AA_BP=54
MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVR
SVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKE
AAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTESQQNGEEGTSTPEDKESGQEGVDSMAEEGTSDSNTGSESNSATV

--------------------------------------------------------------

>39409_39409_8_IKZF3-SMARCE1_IKZF3_chr17_37985639_ENST00000346872_SMARCE1_chr17_38788619_ENST00000348513_length(amino acids)=285AA_BP=54
MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVR
SVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKE
AAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTESQQNGEEGTSTPEDKESGQEGVDSMAEEGTSDSNTGSESNSATV

--------------------------------------------------------------

>39409_39409_9_IKZF3-SMARCE1_IKZF3_chr17_37985639_ENST00000346872_SMARCE1_chr17_38788619_ENST00000377808_length(amino acids)=237AA_BP=54
MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVR
SVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKE

--------------------------------------------------------------

>39409_39409_10_IKZF3-SMARCE1_IKZF3_chr17_37985639_ENST00000346872_SMARCE1_chr17_38788619_ENST00000400122_length(amino acids)=237AA_BP=54
MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVR
SVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKE

--------------------------------------------------------------

>39409_39409_11_IKZF3-SMARCE1_IKZF3_chr17_37985639_ENST00000346872_SMARCE1_chr17_38788619_ENST00000431889_length(amino acids)=285AA_BP=54
MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVR
SVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKE
AAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTESQQNGEEGTSTPEDKESGQEGVDSMAEEGTSDSNTGSESNSATV

--------------------------------------------------------------

>39409_39409_12_IKZF3-SMARCE1_IKZF3_chr17_37985639_ENST00000346872_SMARCE1_chr17_38788619_ENST00000544009_length(amino acids)=285AA_BP=54
MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVR
SVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKE
AAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTESQQNGEEGTSTPEDKESGQEGVDSMAEEGTSDSNTGSESNSATV

--------------------------------------------------------------

>39409_39409_13_IKZF3-SMARCE1_IKZF3_chr17_37985639_ENST00000346872_SMARCE1_chr17_38788619_ENST00000578044_length(amino acids)=285AA_BP=54
MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVR
SVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKE
AAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTESQQNGEEGTSTPEDKESGQEGVDSMAEEGTSDSNTGSESNSATV

--------------------------------------------------------------

>39409_39409_14_IKZF3-SMARCE1_IKZF3_chr17_37985639_ENST00000346872_SMARCE1_chr17_38788619_ENST00000580419_length(amino acids)=285AA_BP=54
MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVR
SVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKE
AAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTESQQNGEEGTSTPEDKESGQEGVDSMAEEGTSDSNTGSESNSATV

--------------------------------------------------------------

>39409_39409_15_IKZF3-SMARCE1_IKZF3_chr17_37985639_ENST00000350532_SMARCE1_chr17_38788619_ENST00000348513_length(amino acids)=285AA_BP=54
MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVR
SVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKE
AAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTESQQNGEEGTSTPEDKESGQEGVDSMAEEGTSDSNTGSESNSATV

--------------------------------------------------------------

>39409_39409_16_IKZF3-SMARCE1_IKZF3_chr17_37985639_ENST00000350532_SMARCE1_chr17_38788619_ENST00000377808_length(amino acids)=237AA_BP=54
MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVR
SVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKE

--------------------------------------------------------------

>39409_39409_17_IKZF3-SMARCE1_IKZF3_chr17_37985639_ENST00000350532_SMARCE1_chr17_38788619_ENST00000400122_length(amino acids)=237AA_BP=54
MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVR
SVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKE

--------------------------------------------------------------

>39409_39409_18_IKZF3-SMARCE1_IKZF3_chr17_37985639_ENST00000350532_SMARCE1_chr17_38788619_ENST00000431889_length(amino acids)=285AA_BP=54
MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVR
SVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKE
AAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTESQQNGEEGTSTPEDKESGQEGVDSMAEEGTSDSNTGSESNSATV

--------------------------------------------------------------

>39409_39409_19_IKZF3-SMARCE1_IKZF3_chr17_37985639_ENST00000350532_SMARCE1_chr17_38788619_ENST00000544009_length(amino acids)=285AA_BP=54
MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVR
SVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKE
AAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTESQQNGEEGTSTPEDKESGQEGVDSMAEEGTSDSNTGSESNSATV

--------------------------------------------------------------

>39409_39409_20_IKZF3-SMARCE1_IKZF3_chr17_37985639_ENST00000350532_SMARCE1_chr17_38788619_ENST00000578044_length(amino acids)=285AA_BP=54
MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVR
SVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKE
AAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTESQQNGEEGTSTPEDKESGQEGVDSMAEEGTSDSNTGSESNSATV

--------------------------------------------------------------

>39409_39409_21_IKZF3-SMARCE1_IKZF3_chr17_37985639_ENST00000350532_SMARCE1_chr17_38788619_ENST00000580419_length(amino acids)=285AA_BP=54
MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVR
SVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKE
AAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTESQQNGEEGTSTPEDKESGQEGVDSMAEEGTSDSNTGSESNSATV

--------------------------------------------------------------

>39409_39409_22_IKZF3-SMARCE1_IKZF3_chr17_37985639_ENST00000351680_SMARCE1_chr17_38788619_ENST00000348513_length(amino acids)=285AA_BP=54
MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVR
SVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKE
AAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTESQQNGEEGTSTPEDKESGQEGVDSMAEEGTSDSNTGSESNSATV

--------------------------------------------------------------

>39409_39409_23_IKZF3-SMARCE1_IKZF3_chr17_37985639_ENST00000351680_SMARCE1_chr17_38788619_ENST00000377808_length(amino acids)=237AA_BP=54
MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVR
SVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKE

--------------------------------------------------------------

>39409_39409_24_IKZF3-SMARCE1_IKZF3_chr17_37985639_ENST00000351680_SMARCE1_chr17_38788619_ENST00000400122_length(amino acids)=237AA_BP=54
MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVR
SVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKE

--------------------------------------------------------------

>39409_39409_25_IKZF3-SMARCE1_IKZF3_chr17_37985639_ENST00000351680_SMARCE1_chr17_38788619_ENST00000431889_length(amino acids)=285AA_BP=54
MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVR
SVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKE
AAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTESQQNGEEGTSTPEDKESGQEGVDSMAEEGTSDSNTGSESNSATV

--------------------------------------------------------------

>39409_39409_26_IKZF3-SMARCE1_IKZF3_chr17_37985639_ENST00000351680_SMARCE1_chr17_38788619_ENST00000544009_length(amino acids)=285AA_BP=54
MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVR
SVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKE
AAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTESQQNGEEGTSTPEDKESGQEGVDSMAEEGTSDSNTGSESNSATV

--------------------------------------------------------------

>39409_39409_27_IKZF3-SMARCE1_IKZF3_chr17_37985639_ENST00000351680_SMARCE1_chr17_38788619_ENST00000578044_length(amino acids)=285AA_BP=54
MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVR
SVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKE
AAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTESQQNGEEGTSTPEDKESGQEGVDSMAEEGTSDSNTGSESNSATV

--------------------------------------------------------------

>39409_39409_28_IKZF3-SMARCE1_IKZF3_chr17_37985639_ENST00000351680_SMARCE1_chr17_38788619_ENST00000580419_length(amino acids)=285AA_BP=54
MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVR
SVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKE
AAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTESQQNGEEGTSTPEDKESGQEGVDSMAEEGTSDSNTGSESNSATV

--------------------------------------------------------------

>39409_39409_29_IKZF3-SMARCE1_IKZF3_chr17_37985639_ENST00000377944_SMARCE1_chr17_38788619_ENST00000348513_length(amino acids)=285AA_BP=54
MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVR
SVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKE
AAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTESQQNGEEGTSTPEDKESGQEGVDSMAEEGTSDSNTGSESNSATV

--------------------------------------------------------------

>39409_39409_30_IKZF3-SMARCE1_IKZF3_chr17_37985639_ENST00000377944_SMARCE1_chr17_38788619_ENST00000377808_length(amino acids)=237AA_BP=54
MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVR
SVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKE

--------------------------------------------------------------

>39409_39409_31_IKZF3-SMARCE1_IKZF3_chr17_37985639_ENST00000377944_SMARCE1_chr17_38788619_ENST00000400122_length(amino acids)=237AA_BP=54
MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVR
SVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKE

--------------------------------------------------------------

>39409_39409_32_IKZF3-SMARCE1_IKZF3_chr17_37985639_ENST00000377944_SMARCE1_chr17_38788619_ENST00000431889_length(amino acids)=285AA_BP=54
MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVR
SVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKE
AAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTESQQNGEEGTSTPEDKESGQEGVDSMAEEGTSDSNTGSESNSATV

--------------------------------------------------------------

>39409_39409_33_IKZF3-SMARCE1_IKZF3_chr17_37985639_ENST00000377944_SMARCE1_chr17_38788619_ENST00000544009_length(amino acids)=285AA_BP=54
MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVR
SVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKE
AAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTESQQNGEEGTSTPEDKESGQEGVDSMAEEGTSDSNTGSESNSATV

--------------------------------------------------------------

>39409_39409_34_IKZF3-SMARCE1_IKZF3_chr17_37985639_ENST00000377944_SMARCE1_chr17_38788619_ENST00000578044_length(amino acids)=285AA_BP=54
MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVR
SVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKE
AAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTESQQNGEEGTSTPEDKESGQEGVDSMAEEGTSDSNTGSESNSATV

--------------------------------------------------------------

>39409_39409_35_IKZF3-SMARCE1_IKZF3_chr17_37985639_ENST00000377944_SMARCE1_chr17_38788619_ENST00000580419_length(amino acids)=285AA_BP=54
MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVR
SVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKE
AAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTESQQNGEEGTSTPEDKESGQEGVDSMAEEGTSDSNTGSESNSATV

--------------------------------------------------------------

>39409_39409_36_IKZF3-SMARCE1_IKZF3_chr17_37985639_ENST00000377945_SMARCE1_chr17_38788619_ENST00000348513_length(amino acids)=285AA_BP=54
MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVR
SVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKE
AAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTESQQNGEEGTSTPEDKESGQEGVDSMAEEGTSDSNTGSESNSATV

--------------------------------------------------------------

>39409_39409_37_IKZF3-SMARCE1_IKZF3_chr17_37985639_ENST00000377945_SMARCE1_chr17_38788619_ENST00000377808_length(amino acids)=237AA_BP=54
MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVR
SVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKE

--------------------------------------------------------------

>39409_39409_38_IKZF3-SMARCE1_IKZF3_chr17_37985639_ENST00000377945_SMARCE1_chr17_38788619_ENST00000400122_length(amino acids)=237AA_BP=54
MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVR
SVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKE

--------------------------------------------------------------

>39409_39409_39_IKZF3-SMARCE1_IKZF3_chr17_37985639_ENST00000377945_SMARCE1_chr17_38788619_ENST00000431889_length(amino acids)=285AA_BP=54
MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVR
SVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKE
AAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTESQQNGEEGTSTPEDKESGQEGVDSMAEEGTSDSNTGSESNSATV

--------------------------------------------------------------

>39409_39409_40_IKZF3-SMARCE1_IKZF3_chr17_37985639_ENST00000377945_SMARCE1_chr17_38788619_ENST00000544009_length(amino acids)=285AA_BP=54
MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVR
SVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKE
AAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTESQQNGEEGTSTPEDKESGQEGVDSMAEEGTSDSNTGSESNSATV

--------------------------------------------------------------

>39409_39409_41_IKZF3-SMARCE1_IKZF3_chr17_37985639_ENST00000377945_SMARCE1_chr17_38788619_ENST00000578044_length(amino acids)=285AA_BP=54
MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVR
SVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKE
AAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTESQQNGEEGTSTPEDKESGQEGVDSMAEEGTSDSNTGSESNSATV

--------------------------------------------------------------

>39409_39409_42_IKZF3-SMARCE1_IKZF3_chr17_37985639_ENST00000377945_SMARCE1_chr17_38788619_ENST00000580419_length(amino acids)=285AA_BP=54
MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVR
SVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKE
AAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTESQQNGEEGTSTPEDKESGQEGVDSMAEEGTSDSNTGSESNSATV

--------------------------------------------------------------

>39409_39409_43_IKZF3-SMARCE1_IKZF3_chr17_37985639_ENST00000377952_SMARCE1_chr17_38788619_ENST00000348513_length(amino acids)=285AA_BP=54
MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVR
SVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKE
AAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTESQQNGEEGTSTPEDKESGQEGVDSMAEEGTSDSNTGSESNSATV

--------------------------------------------------------------

>39409_39409_44_IKZF3-SMARCE1_IKZF3_chr17_37985639_ENST00000377952_SMARCE1_chr17_38788619_ENST00000377808_length(amino acids)=237AA_BP=54
MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVR
SVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKE

--------------------------------------------------------------

>39409_39409_45_IKZF3-SMARCE1_IKZF3_chr17_37985639_ENST00000377952_SMARCE1_chr17_38788619_ENST00000400122_length(amino acids)=237AA_BP=54
MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVR
SVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKE

--------------------------------------------------------------

>39409_39409_46_IKZF3-SMARCE1_IKZF3_chr17_37985639_ENST00000377952_SMARCE1_chr17_38788619_ENST00000431889_length(amino acids)=285AA_BP=54
MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVR
SVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKE
AAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTESQQNGEEGTSTPEDKESGQEGVDSMAEEGTSDSNTGSESNSATV

--------------------------------------------------------------

>39409_39409_47_IKZF3-SMARCE1_IKZF3_chr17_37985639_ENST00000377952_SMARCE1_chr17_38788619_ENST00000544009_length(amino acids)=285AA_BP=54
MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVR
SVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKE
AAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTESQQNGEEGTSTPEDKESGQEGVDSMAEEGTSDSNTGSESNSATV

--------------------------------------------------------------

>39409_39409_48_IKZF3-SMARCE1_IKZF3_chr17_37985639_ENST00000377952_SMARCE1_chr17_38788619_ENST00000578044_length(amino acids)=285AA_BP=54
MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVR
SVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKE
AAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTESQQNGEEGTSTPEDKESGQEGVDSMAEEGTSDSNTGSESNSATV

--------------------------------------------------------------

>39409_39409_49_IKZF3-SMARCE1_IKZF3_chr17_37985639_ENST00000377952_SMARCE1_chr17_38788619_ENST00000580419_length(amino acids)=285AA_BP=54
MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVR
SVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKE
AAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTESQQNGEEGTSTPEDKESGQEGVDSMAEEGTSDSNTGSESNSATV

--------------------------------------------------------------

>39409_39409_50_IKZF3-SMARCE1_IKZF3_chr17_37985639_ENST00000377958_SMARCE1_chr17_38788619_ENST00000348513_length(amino acids)=285AA_BP=54
MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVR
SVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKE
AAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTESQQNGEEGTSTPEDKESGQEGVDSMAEEGTSDSNTGSESNSATV

--------------------------------------------------------------

>39409_39409_51_IKZF3-SMARCE1_IKZF3_chr17_37985639_ENST00000377958_SMARCE1_chr17_38788619_ENST00000377808_length(amino acids)=237AA_BP=54
MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVR
SVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKE

--------------------------------------------------------------

>39409_39409_52_IKZF3-SMARCE1_IKZF3_chr17_37985639_ENST00000377958_SMARCE1_chr17_38788619_ENST00000400122_length(amino acids)=237AA_BP=54
MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVR
SVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKE

--------------------------------------------------------------

>39409_39409_53_IKZF3-SMARCE1_IKZF3_chr17_37985639_ENST00000377958_SMARCE1_chr17_38788619_ENST00000431889_length(amino acids)=285AA_BP=54
MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVR
SVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKE
AAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTESQQNGEEGTSTPEDKESGQEGVDSMAEEGTSDSNTGSESNSATV

--------------------------------------------------------------

>39409_39409_54_IKZF3-SMARCE1_IKZF3_chr17_37985639_ENST00000377958_SMARCE1_chr17_38788619_ENST00000544009_length(amino acids)=285AA_BP=54
MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVR
SVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKE
AAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTESQQNGEEGTSTPEDKESGQEGVDSMAEEGTSDSNTGSESNSATV

--------------------------------------------------------------

>39409_39409_55_IKZF3-SMARCE1_IKZF3_chr17_37985639_ENST00000377958_SMARCE1_chr17_38788619_ENST00000578044_length(amino acids)=285AA_BP=54
MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVR
SVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKE
AAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTESQQNGEEGTSTPEDKESGQEGVDSMAEEGTSDSNTGSESNSATV

--------------------------------------------------------------

>39409_39409_56_IKZF3-SMARCE1_IKZF3_chr17_37985639_ENST00000377958_SMARCE1_chr17_38788619_ENST00000580419_length(amino acids)=285AA_BP=54
MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVR
SVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKE
AAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTESQQNGEEGTSTPEDKESGQEGVDSMAEEGTSDSNTGSESNSATV

--------------------------------------------------------------

>39409_39409_57_IKZF3-SMARCE1_IKZF3_chr17_37985639_ENST00000394189_SMARCE1_chr17_38788619_ENST00000348513_length(amino acids)=285AA_BP=54
MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVR
SVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKE
AAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTESQQNGEEGTSTPEDKESGQEGVDSMAEEGTSDSNTGSESNSATV

--------------------------------------------------------------

>39409_39409_58_IKZF3-SMARCE1_IKZF3_chr17_37985639_ENST00000394189_SMARCE1_chr17_38788619_ENST00000377808_length(amino acids)=237AA_BP=54
MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVR
SVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKE

--------------------------------------------------------------

>39409_39409_59_IKZF3-SMARCE1_IKZF3_chr17_37985639_ENST00000394189_SMARCE1_chr17_38788619_ENST00000400122_length(amino acids)=237AA_BP=54
MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVR
SVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKE

--------------------------------------------------------------

>39409_39409_60_IKZF3-SMARCE1_IKZF3_chr17_37985639_ENST00000394189_SMARCE1_chr17_38788619_ENST00000431889_length(amino acids)=285AA_BP=54
MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVR
SVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKE
AAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTESQQNGEEGTSTPEDKESGQEGVDSMAEEGTSDSNTGSESNSATV

--------------------------------------------------------------

>39409_39409_61_IKZF3-SMARCE1_IKZF3_chr17_37985639_ENST00000394189_SMARCE1_chr17_38788619_ENST00000544009_length(amino acids)=285AA_BP=54
MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVR
SVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKE
AAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTESQQNGEEGTSTPEDKESGQEGVDSMAEEGTSDSNTGSESNSATV

--------------------------------------------------------------

>39409_39409_62_IKZF3-SMARCE1_IKZF3_chr17_37985639_ENST00000394189_SMARCE1_chr17_38788619_ENST00000578044_length(amino acids)=285AA_BP=54
MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVR
SVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKE
AAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTESQQNGEEGTSTPEDKESGQEGVDSMAEEGTSDSNTGSESNSATV

--------------------------------------------------------------

>39409_39409_63_IKZF3-SMARCE1_IKZF3_chr17_37985639_ENST00000394189_SMARCE1_chr17_38788619_ENST00000580419_length(amino acids)=285AA_BP=54
MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVR
SVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKE
AAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTESQQNGEEGTSTPEDKESGQEGVDSMAEEGTSDSNTGSESNSATV

--------------------------------------------------------------

>39409_39409_64_IKZF3-SMARCE1_IKZF3_chr17_37985639_ENST00000439016_SMARCE1_chr17_38788619_ENST00000348513_length(amino acids)=285AA_BP=54
MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVR
SVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKE
AAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTESQQNGEEGTSTPEDKESGQEGVDSMAEEGTSDSNTGSESNSATV

--------------------------------------------------------------

>39409_39409_65_IKZF3-SMARCE1_IKZF3_chr17_37985639_ENST00000439016_SMARCE1_chr17_38788619_ENST00000377808_length(amino acids)=237AA_BP=54
MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVR
SVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKE

--------------------------------------------------------------

>39409_39409_66_IKZF3-SMARCE1_IKZF3_chr17_37985639_ENST00000439016_SMARCE1_chr17_38788619_ENST00000400122_length(amino acids)=237AA_BP=54
MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVR
SVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKE

--------------------------------------------------------------

>39409_39409_67_IKZF3-SMARCE1_IKZF3_chr17_37985639_ENST00000439016_SMARCE1_chr17_38788619_ENST00000431889_length(amino acids)=285AA_BP=54
MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVR
SVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKE
AAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTESQQNGEEGTSTPEDKESGQEGVDSMAEEGTSDSNTGSESNSATV

--------------------------------------------------------------

>39409_39409_68_IKZF3-SMARCE1_IKZF3_chr17_37985639_ENST00000439016_SMARCE1_chr17_38788619_ENST00000544009_length(amino acids)=285AA_BP=54
MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVR
SVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKE
AAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTESQQNGEEGTSTPEDKESGQEGVDSMAEEGTSDSNTGSESNSATV

--------------------------------------------------------------

>39409_39409_69_IKZF3-SMARCE1_IKZF3_chr17_37985639_ENST00000439016_SMARCE1_chr17_38788619_ENST00000578044_length(amino acids)=285AA_BP=54
MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVR
SVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKE
AAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTESQQNGEEGTSTPEDKESGQEGVDSMAEEGTSDSNTGSESNSATV

--------------------------------------------------------------

>39409_39409_70_IKZF3-SMARCE1_IKZF3_chr17_37985639_ENST00000439016_SMARCE1_chr17_38788619_ENST00000580419_length(amino acids)=285AA_BP=54
MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVR
SVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKE
AAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTESQQNGEEGTSTPEDKESGQEGVDSMAEEGTSDSNTGSESNSATV

--------------------------------------------------------------

>39409_39409_71_IKZF3-SMARCE1_IKZF3_chr17_37985639_ENST00000467757_SMARCE1_chr17_38788619_ENST00000348513_length(amino acids)=285AA_BP=54
MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVR
SVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKE
AAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTESQQNGEEGTSTPEDKESGQEGVDSMAEEGTSDSNTGSESNSATV

--------------------------------------------------------------

>39409_39409_72_IKZF3-SMARCE1_IKZF3_chr17_37985639_ENST00000467757_SMARCE1_chr17_38788619_ENST00000377808_length(amino acids)=237AA_BP=54
MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVR
SVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKE

--------------------------------------------------------------

>39409_39409_73_IKZF3-SMARCE1_IKZF3_chr17_37985639_ENST00000467757_SMARCE1_chr17_38788619_ENST00000400122_length(amino acids)=237AA_BP=54
MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVR
SVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKE

--------------------------------------------------------------

>39409_39409_74_IKZF3-SMARCE1_IKZF3_chr17_37985639_ENST00000467757_SMARCE1_chr17_38788619_ENST00000431889_length(amino acids)=285AA_BP=54
MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVR
SVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKE
AAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTESQQNGEEGTSTPEDKESGQEGVDSMAEEGTSDSNTGSESNSATV

--------------------------------------------------------------

>39409_39409_75_IKZF3-SMARCE1_IKZF3_chr17_37985639_ENST00000467757_SMARCE1_chr17_38788619_ENST00000544009_length(amino acids)=285AA_BP=54
MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVR
SVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKE
AAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTESQQNGEEGTSTPEDKESGQEGVDSMAEEGTSDSNTGSESNSATV

--------------------------------------------------------------

>39409_39409_76_IKZF3-SMARCE1_IKZF3_chr17_37985639_ENST00000467757_SMARCE1_chr17_38788619_ENST00000578044_length(amino acids)=285AA_BP=54
MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVR
SVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKE
AAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTESQQNGEEGTSTPEDKESGQEGVDSMAEEGTSDSNTGSESNSATV

--------------------------------------------------------------

>39409_39409_77_IKZF3-SMARCE1_IKZF3_chr17_37985639_ENST00000467757_SMARCE1_chr17_38788619_ENST00000580419_length(amino acids)=285AA_BP=54
MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVR
SVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKE
AAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTESQQNGEEGTSTPEDKESGQEGVDSMAEEGTSDSNTGSESNSATV

--------------------------------------------------------------

Top

Fusion Protein Functional Features

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr17:37985639/chr17:38788619)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
IKZF3 Q9UKT9	.
FUNCTION: Transcription factor that plays an important role in the regulation of lymphocyte differentiation. Plays an essential role in regulation of B-cell differentiation, proliferation and maturation to an effector state. Involved in regulating BCL2 expression and controlling apoptosis in T-cells in an IL2-dependent manner. {ECO:0000269\|PubMed:10369681}.	FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page
* Minus value of BPloci means that the break pointn is located before the CDS.

- Retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Tgene

SMARCE1

chr17:37985639

chr17:38788619

ENST00000348513

220_319

180.33333333333334

412.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

SMARCE1

chr17:37985639

chr17:38788619

ENST00000377808

220_319

145.33333333333334

394.3333333333333

Coiled coil

Ontology_term=ECO:0000255

Tgene

SMARCE1

chr17:37985639

chr17:38788619

ENST00000400122

220_319

110.33333333333333

359.3333333333333

Coiled coil

Ontology_term=ECO:0000255

Tgene

SMARCE1

chr17:37985639

chr17:38788619

ENST00000544009

220_319

110.33333333333333

342.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

SMARCE1

chr17:37985639

chr17:38788619

ENST00000578044

220_319

110.33333333333333

342.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

SMARCE1

chr17:37985639

chr17:38788619

ENST00000580419

220_319

145.33333333333334

377.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

SMARCE1

chr17:37985639

chr17:38788619

ENST00000348513

320_411

180.33333333333334

412.0

Compositional bias

Note=Glu-rich

Tgene

SMARCE1

chr17:37985639

chr17:38788619

ENST00000377808

320_411

145.33333333333334

394.3333333333333

Compositional bias

Note=Glu-rich

Tgene

SMARCE1

chr17:37985639

chr17:38788619

ENST00000400122

320_411

110.33333333333333

359.3333333333333

Compositional bias

Note=Glu-rich

Tgene

SMARCE1

chr17:37985639

chr17:38788619

ENST00000544009

320_411

110.33333333333333

342.0

Compositional bias

Note=Glu-rich

Tgene

SMARCE1

chr17:37985639

chr17:38788619

ENST00000578044

320_411

110.33333333333333

342.0

Compositional bias

Note=Glu-rich

Tgene

SMARCE1

chr17:37985639

chr17:38788619

ENST00000580419

320_411

145.33333333333334

377.0

Compositional bias

Note=Glu-rich

- Not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

IKZF3

chr17:37985639

chr17:38788619

ENST00000346243

118_140

54.333333333333336

432.0

Zinc finger

C2H2-type 1

Hgene

IKZF3

chr17:37985639

chr17:38788619

ENST00000346243

146_168

54.333333333333336

432.0

Zinc finger

C2H2-type 2

Hgene

IKZF3

chr17:37985639

chr17:38788619

ENST00000346243

174_196

54.333333333333336

432.0

Zinc finger

C2H2-type 3

Hgene

IKZF3

chr17:37985639

chr17:38788619

ENST00000346243

202_224

54.333333333333336

432.0

Zinc finger

C2H2-type 4%3B atypical

Hgene

IKZF3

chr17:37985639

chr17:38788619

ENST00000346243

452_474

54.333333333333336

432.0

Zinc finger

C2H2-type 5

Hgene

IKZF3

chr17:37985639

chr17:38788619

ENST00000346243

480_504

54.333333333333336

432.0

Zinc finger

C2H2-type 6%3B atypical

Hgene

IKZF3

chr17:37985639

chr17:38788619

ENST00000346872

118_140

54.333333333333336

510.0

Zinc finger

C2H2-type 1

Hgene

IKZF3

chr17:37985639

chr17:38788619

ENST00000346872

146_168

54.333333333333336

510.0

Zinc finger

C2H2-type 2

Hgene

IKZF3

chr17:37985639

chr17:38788619

ENST00000346872

174_196

54.333333333333336

510.0

Zinc finger

C2H2-type 3

Hgene

IKZF3

chr17:37985639

chr17:38788619

ENST00000346872

202_224

54.333333333333336

510.0

Zinc finger

C2H2-type 4%3B atypical

Hgene

IKZF3

chr17:37985639

chr17:38788619

ENST00000346872

452_474

54.333333333333336

510.0

Zinc finger

C2H2-type 5

Hgene

IKZF3

chr17:37985639

chr17:38788619

ENST00000346872

480_504

54.333333333333336

510.0

Zinc finger

C2H2-type 6%3B atypical

Hgene

IKZF3

chr17:37985639

chr17:38788619

ENST00000350532

118_140

54.333333333333336

471.0

Zinc finger

C2H2-type 1

Hgene

IKZF3

chr17:37985639

chr17:38788619

ENST00000350532

146_168

54.333333333333336

471.0

Zinc finger

C2H2-type 2

Hgene

IKZF3

chr17:37985639

chr17:38788619

ENST00000350532

174_196

54.333333333333336

471.0

Zinc finger

C2H2-type 3

Hgene

IKZF3

chr17:37985639

chr17:38788619

ENST00000350532

202_224

54.333333333333336

471.0

Zinc finger

C2H2-type 4%3B atypical

Hgene

IKZF3

chr17:37985639

chr17:38788619

ENST00000350532

452_474

54.333333333333336

471.0

Zinc finger

C2H2-type 5

Hgene

IKZF3

chr17:37985639

chr17:38788619

ENST00000350532

480_504

54.333333333333336

471.0

Zinc finger

C2H2-type 6%3B atypical

Hgene

IKZF3

chr17:37985639

chr17:38788619

ENST00000351680

118_140

54.333333333333336

471.0

Zinc finger

C2H2-type 1

Hgene

IKZF3

chr17:37985639

chr17:38788619

ENST00000351680

146_168

54.333333333333336

471.0

Zinc finger

C2H2-type 2

Hgene

IKZF3

chr17:37985639

chr17:38788619

ENST00000351680

174_196

54.333333333333336

471.0

Zinc finger

C2H2-type 3

Hgene

IKZF3

chr17:37985639

chr17:38788619

ENST00000351680

202_224

54.333333333333336

471.0

Zinc finger

C2H2-type 4%3B atypical

Hgene

IKZF3

chr17:37985639

chr17:38788619

ENST00000351680

452_474

54.333333333333336

471.0

Zinc finger

C2H2-type 5

Hgene

IKZF3

chr17:37985639

chr17:38788619

ENST00000351680

480_504

54.333333333333336

471.0

Zinc finger

C2H2-type 6%3B atypical

Hgene

IKZF3

chr17:37985639

chr17:38788619

ENST00000377944

118_140

54.333333333333336

367.0

Zinc finger

C2H2-type 1

Hgene

IKZF3

chr17:37985639

chr17:38788619

ENST00000377944

146_168

54.333333333333336

367.0

Zinc finger

C2H2-type 2

Hgene

IKZF3

chr17:37985639

chr17:38788619

ENST00000377944

174_196

54.333333333333336

367.0

Zinc finger

C2H2-type 3

Hgene

IKZF3

chr17:37985639

chr17:38788619

ENST00000377944

202_224

54.333333333333336

367.0

Zinc finger

C2H2-type 4%3B atypical

Hgene

IKZF3

chr17:37985639

chr17:38788619

ENST00000377944

452_474

54.333333333333336

367.0

Zinc finger

C2H2-type 5

Hgene

IKZF3

chr17:37985639

chr17:38788619

ENST00000377944

480_504

54.333333333333336

367.0

Zinc finger

C2H2-type 6%3B atypical

Hgene

IKZF3

chr17:37985639

chr17:38788619

ENST00000377945

118_140

54.333333333333336

376.0

Zinc finger

C2H2-type 1

Hgene

IKZF3

chr17:37985639

chr17:38788619

ENST00000377945

146_168

54.333333333333336

376.0

Zinc finger

C2H2-type 2

Hgene

IKZF3

chr17:37985639

chr17:38788619

ENST00000377945

174_196

54.333333333333336

376.0

Zinc finger

C2H2-type 3

Hgene

IKZF3

chr17:37985639

chr17:38788619

ENST00000377945

202_224

54.333333333333336

376.0

Zinc finger

C2H2-type 4%3B atypical

Hgene

IKZF3

chr17:37985639

chr17:38788619

ENST00000377945

452_474

54.333333333333336

376.0

Zinc finger

C2H2-type 5

Hgene

IKZF3

chr17:37985639

chr17:38788619

ENST00000377945

480_504

54.333333333333336

376.0

Zinc finger

C2H2-type 6%3B atypical

Hgene

IKZF3

chr17:37985639

chr17:38788619

ENST00000377952

118_140

54.333333333333336

289.0

Zinc finger

C2H2-type 1

Hgene

IKZF3

chr17:37985639

chr17:38788619

ENST00000377952

146_168

54.333333333333336

289.0

Zinc finger

C2H2-type 2

Hgene

IKZF3

chr17:37985639

chr17:38788619

ENST00000377952

174_196

54.333333333333336

289.0

Zinc finger

C2H2-type 3

Hgene

IKZF3

chr17:37985639

chr17:38788619

ENST00000377952

202_224

54.333333333333336

289.0

Zinc finger

C2H2-type 4%3B atypical

Hgene

IKZF3

chr17:37985639

chr17:38788619

ENST00000377952

452_474

54.333333333333336

289.0

Zinc finger

C2H2-type 5

Hgene

IKZF3

chr17:37985639

chr17:38788619

ENST00000377952

480_504

54.333333333333336

289.0

Zinc finger

C2H2-type 6%3B atypical

Hgene

IKZF3

chr17:37985639

chr17:38788619

ENST00000377958

118_140

54.333333333333336

423.0

Zinc finger

C2H2-type 1

Hgene

IKZF3

chr17:37985639

chr17:38788619

ENST00000377958

146_168

54.333333333333336

423.0

Zinc finger

C2H2-type 2

Hgene

IKZF3

chr17:37985639

chr17:38788619

ENST00000377958

174_196

54.333333333333336

423.0

Zinc finger

C2H2-type 3

Hgene

IKZF3

chr17:37985639

chr17:38788619

ENST00000377958

202_224

54.333333333333336

423.0

Zinc finger

C2H2-type 4%3B atypical

Hgene

IKZF3

chr17:37985639

chr17:38788619

ENST00000377958

452_474

54.333333333333336

423.0

Zinc finger

C2H2-type 5

Hgene

IKZF3

chr17:37985639

chr17:38788619

ENST00000377958

480_504

54.333333333333336

423.0

Zinc finger

C2H2-type 6%3B atypical

Hgene

IKZF3

chr17:37985639

chr17:38788619

ENST00000394189

118_140

54.333333333333336

328.0

Zinc finger

C2H2-type 1

Hgene

IKZF3

chr17:37985639

chr17:38788619

ENST00000394189

146_168

54.333333333333336

328.0

Zinc finger

C2H2-type 2

Hgene

IKZF3

chr17:37985639

chr17:38788619

ENST00000394189

174_196

54.333333333333336

328.0

Zinc finger

C2H2-type 3

Hgene

IKZF3

chr17:37985639

chr17:38788619

ENST00000394189

202_224

54.333333333333336

328.0

Zinc finger

C2H2-type 4%3B atypical

Hgene

IKZF3

chr17:37985639

chr17:38788619

ENST00000394189

452_474

54.333333333333336

328.0

Zinc finger

C2H2-type 5

Hgene

IKZF3

chr17:37985639

chr17:38788619

ENST00000394189

480_504

54.333333333333336

328.0

Zinc finger

C2H2-type 6%3B atypical

Hgene

IKZF3

chr17:37985639

chr17:38788619

ENST00000439016

118_140

54.333333333333336

415.0

Zinc finger

C2H2-type 1

Hgene

IKZF3

chr17:37985639

chr17:38788619

ENST00000439016

146_168

54.333333333333336

415.0

Zinc finger

C2H2-type 2

Hgene

IKZF3

chr17:37985639

chr17:38788619

ENST00000439016

174_196

54.333333333333336

415.0

Zinc finger

C2H2-type 3

Hgene

IKZF3

chr17:37985639

chr17:38788619

ENST00000439016

202_224

54.333333333333336

415.0

Zinc finger

C2H2-type 4%3B atypical

Hgene

IKZF3

chr17:37985639

chr17:38788619

ENST00000439016

452_474

54.333333333333336

415.0

Zinc finger

C2H2-type 5

Hgene

IKZF3

chr17:37985639

chr17:38788619

ENST00000439016

480_504

54.333333333333336

415.0

Zinc finger

C2H2-type 6%3B atypical

Hgene

IKZF3

chr17:37985639

chr17:38788619

ENST00000439167

118_140

437.0

Zinc finger

C2H2-type 1

Hgene

IKZF3

chr17:37985639

chr17:38788619

ENST00000439167

146_168

437.0

Zinc finger

C2H2-type 2

Hgene

IKZF3

chr17:37985639

chr17:38788619

ENST00000439167

174_196

437.0

Zinc finger

C2H2-type 3

Hgene

IKZF3

chr17:37985639

chr17:38788619

ENST00000439167

202_224

437.0

Zinc finger

C2H2-type 4%3B atypical

Hgene

IKZF3

chr17:37985639

chr17:38788619

ENST00000439167

452_474

437.0

Zinc finger

C2H2-type 5

Hgene

IKZF3

chr17:37985639

chr17:38788619

ENST00000439167

480_504

437.0

Zinc finger

C2H2-type 6%3B atypical

Hgene

IKZF3

chr17:37985639

chr17:38788619

ENST00000467757

118_140

54.333333333333336

454.0

Zinc finger

C2H2-type 1

Hgene

IKZF3

chr17:37985639

chr17:38788619

ENST00000467757

146_168

54.333333333333336

454.0

Zinc finger

C2H2-type 2

Hgene

IKZF3

chr17:37985639

chr17:38788619

ENST00000467757

174_196

54.333333333333336

454.0

Zinc finger

C2H2-type 3

Hgene

IKZF3

chr17:37985639

chr17:38788619

ENST00000467757

202_224

54.333333333333336

454.0

Zinc finger

C2H2-type 4%3B atypical

Hgene

IKZF3

chr17:37985639

chr17:38788619

ENST00000467757

452_474

54.333333333333336

454.0

Zinc finger

C2H2-type 5

Hgene

IKZF3

chr17:37985639

chr17:38788619

ENST00000467757

480_504

54.333333333333336

454.0

Zinc finger

C2H2-type 6%3B atypical

Hgene

IKZF3

chr17:37985639

chr17:38788619

ENST00000535189

118_140

476.0

Zinc finger

C2H2-type 1

Hgene

IKZF3

chr17:37985639

chr17:38788619

ENST00000535189

146_168

476.0

Zinc finger

C2H2-type 2

Hgene

IKZF3

chr17:37985639

chr17:38788619

ENST00000535189

174_196

476.0

Zinc finger

C2H2-type 3

Hgene

IKZF3

chr17:37985639

chr17:38788619

ENST00000535189

202_224

476.0

Zinc finger

C2H2-type 4%3B atypical

Hgene

IKZF3

chr17:37985639

chr17:38788619

ENST00000535189

452_474

476.0

Zinc finger

C2H2-type 5

Hgene

IKZF3

chr17:37985639

chr17:38788619

ENST00000535189

480_504

476.0

Zinc finger

C2H2-type 6%3B atypical

Tgene

SMARCE1

chr17:37985639

chr17:38788619

ENST00000348513

5_65

180.33333333333334

412.0

Compositional bias

Note=Pro-rich

Tgene

SMARCE1

chr17:37985639

chr17:38788619

ENST00000377808

5_65

145.33333333333334

394.3333333333333

Compositional bias

Note=Pro-rich

Tgene

SMARCE1

chr17:37985639

chr17:38788619

ENST00000400122

5_65

110.33333333333333

359.3333333333333

Compositional bias

Note=Pro-rich

Tgene

SMARCE1

chr17:37985639

chr17:38788619

ENST00000544009

5_65

110.33333333333333

342.0

Compositional bias

Note=Pro-rich

Tgene

SMARCE1

chr17:37985639

chr17:38788619

ENST00000578044

5_65

110.33333333333333

342.0

Compositional bias

Note=Pro-rich

Tgene

SMARCE1

chr17:37985639

chr17:38788619

ENST00000580419

5_65

145.33333333333334

377.0

Compositional bias

Note=Pro-rich

Tgene

SMARCE1

chr17:37985639

chr17:38788619

ENST00000348513

66_134

180.33333333333334

412.0

DNA binding

HMG box

Tgene

SMARCE1

chr17:37985639

chr17:38788619

ENST00000377808

66_134

145.33333333333334

394.3333333333333

DNA binding

HMG box

Tgene

SMARCE1

chr17:37985639

chr17:38788619

ENST00000400122

66_134

110.33333333333333

359.3333333333333

DNA binding

HMG box

Tgene

SMARCE1

chr17:37985639

chr17:38788619

ENST00000544009

66_134

110.33333333333333

342.0

DNA binding

HMG box

Tgene

SMARCE1

chr17:37985639

chr17:38788619

ENST00000578044

66_134

110.33333333333333

342.0

DNA binding

HMG box

Tgene

SMARCE1

chr17:37985639

chr17:38788619

ENST00000580419

66_134

145.33333333333334

377.0

DNA binding

HMG box

Top

Fusion Protein-Protein Interaction

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type from validated records (BIOGRID-3.4.160)

Gene

PPI interactors

Protein-protein interactors based on sequence similarity (STRING)

Gene	STRING network
IKZF3
SMARCE1

- Retained interactions in fusion protein (protein functional feature from UniProt).

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost interactions due to fusion (protein functional feature from UniProt).

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Related Drugs to IKZF3-SMARCE1

Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)

Hgene

Tgene

Drug

Source

PMID

Top

Related Diseases to IKZF3-SMARCE1

Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)

Hgene

Tgene

Disease

Source

PMID

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source