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Center for Computational Systems Medicine level1
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Fusion Gene Summary

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Fusion Gene Sample Information

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Fusion ORF Analysis

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Fusion Amino Acid Sequences

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Fusion Protein Functional Features

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Fusion Protein-Protein Interaction

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Related drugs with this fusion protein

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Related disease with this fusion protein

Fusion Protein:ITGB4-LLGL2

Fusion Protein Summary

check button Fusion gene summary
Fusion partner gene informationFusion gene name: ITGB4-LLGL2
FusionPDB ID: 40536
FusionGDB2.0 ID: 40536
HgeneTgene
Gene symbol

ITGB4

LLGL2

Gene ID

3691

3993

Gene nameintegrin subunit beta 4LLGL scribble cell polarity complex component 2
SynonymsCD104|GP150HGL|Hugl-2|LGL2
Cytomap

17q25.1

17q25.1

Type of geneprotein-codingprotein-coding
Descriptionintegrin beta-4CD104 antigenLLGL scribble cell polarity complex component 2LLGL2, scribble cell polarity complex componenthuman giant larvae homologlethal giant larvae homolog 2, scribble cell polarity complex componentlethal(2) giant larvae protein homolog 2
Modification date2020032920200320
UniProtAcc

P16144

Q6P1M3

Ensembl transtripts involved in fusion geneENST idsENST00000584558, ENST00000200181, 
ENST00000339591, ENST00000449880, 
ENST00000450894, ENST00000579662, 
ENST00000167462, ENST00000375227, 
ENST00000392550, ENST00000577200, 
ENST00000578363, 
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)* DoF score23 X 19 X 10=437010 X 11 X 6=660
# samples 2914
** MAII scorelog2(29/4370*10)=-3.91350847437303
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(14/660*10)=-2.23703919730085
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context (manual curation of fusion genes in FusionPDB)

PubMed: ITGB4 [Title/Abstract] AND LLGL2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)LLGL2(73529786)-ITGB4(73748255), # samples:2
ITGB4(73723586)-LLGL2(73552127), # samples:1
ITGB4(73723586)-LLGL2(73552126), # samples:1
Anticipated loss of major functional domain due to fusion event.ITGB4-LLGL2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ITGB4-LLGL2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ITGB4-LLGL2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
ITGB4-LLGL2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneITGB4

GO:0009611

response to wounding

19403692

HgeneITGB4

GO:0031581

hemidesmosome assembly

12482924

TgeneLLGL2

GO:0032878

regulation of establishment or maintenance of cell polarity

12725730


check buttonFusion gene breakpoints across ITGB4 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across LLGL2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure


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Fusion Gene Sample Information

check buttonFusion gene information from FusionGDB2.0.
check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-VQ-A92D-01AITGB4chr17

73723586

+LLGL2chr17

73552127

+
ChimerDB4STADTCGA-VQ-A92DITGB4chr17

73723586

+LLGL2chr17

73552126

+


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Fusion ORF Analysis


check buttonFusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000579662ITGB4chr1773723586+ENST00000167462LLGL2chr1773552127+378551024634821078
ENST00000579662ITGB4chr1773723586+ENST00000375227LLGL2chr1773552127+16855102461505419
ENST00000579662ITGB4chr1773723586+ENST00000392550LLGL2chr1773552127+382751024634971083
ENST00000579662ITGB4chr1773723586+ENST00000578363LLGL2chr1773552127+16875102461505419
ENST00000579662ITGB4chr1773723586+ENST00000577200LLGL2chr1773552127+352351024634941082
ENST00000339591ITGB4chr1773723586+ENST00000167462LLGL2chr1773552127+372645116334231086
ENST00000339591ITGB4chr1773723586+ENST00000375227LLGL2chr1773552127+16264511631446427
ENST00000339591ITGB4chr1773723586+ENST00000392550LLGL2chr1773552127+376845116334381091
ENST00000339591ITGB4chr1773723586+ENST00000578363LLGL2chr1773552127+16284511631446427
ENST00000339591ITGB4chr1773723586+ENST00000577200LLGL2chr1773552127+346445116334351090
ENST00000200181ITGB4chr1773723586+ENST00000167462LLGL2chr1773552127+372645116334231086
ENST00000200181ITGB4chr1773723586+ENST00000375227LLGL2chr1773552127+16264511631446427
ENST00000200181ITGB4chr1773723586+ENST00000392550LLGL2chr1773552127+376845116334381091
ENST00000200181ITGB4chr1773723586+ENST00000578363LLGL2chr1773552127+16284511631446427
ENST00000200181ITGB4chr1773723586+ENST00000577200LLGL2chr1773552127+346445116334351090
ENST00000450894ITGB4chr1773723586+ENST00000167462LLGL2chr1773552127+366539010233621086
ENST00000450894ITGB4chr1773723586+ENST00000375227LLGL2chr1773552127+15653901021385427
ENST00000450894ITGB4chr1773723586+ENST00000392550LLGL2chr1773552127+370739010233771091
ENST00000450894ITGB4chr1773723586+ENST00000578363LLGL2chr1773552127+15673901021385427
ENST00000450894ITGB4chr1773723586+ENST00000577200LLGL2chr1773552127+340339010233741090
ENST00000449880ITGB4chr1773723586+ENST00000167462LLGL2chr1773552127+3547272832441078
ENST00000449880ITGB4chr1773723586+ENST00000375227LLGL2chr1773552127+144727281267419
ENST00000449880ITGB4chr1773723586+ENST00000392550LLGL2chr1773552127+3589272832591083
ENST00000449880ITGB4chr1773723586+ENST00000578363LLGL2chr1773552127+144927281267419
ENST00000449880ITGB4chr1773723586+ENST00000577200LLGL2chr1773552127+3285272832561082
ENST00000579662ITGB4chr1773723586+ENST00000167462LLGL2chr1773552126+378551024634821078
ENST00000579662ITGB4chr1773723586+ENST00000375227LLGL2chr1773552126+16855102461505419
ENST00000579662ITGB4chr1773723586+ENST00000392550LLGL2chr1773552126+382751024634971083
ENST00000579662ITGB4chr1773723586+ENST00000578363LLGL2chr1773552126+16875102461505419
ENST00000579662ITGB4chr1773723586+ENST00000577200LLGL2chr1773552126+352351024634941082
ENST00000339591ITGB4chr1773723586+ENST00000167462LLGL2chr1773552126+372645116334231086
ENST00000339591ITGB4chr1773723586+ENST00000375227LLGL2chr1773552126+16264511631446427
ENST00000339591ITGB4chr1773723586+ENST00000392550LLGL2chr1773552126+376845116334381091
ENST00000339591ITGB4chr1773723586+ENST00000578363LLGL2chr1773552126+16284511631446427
ENST00000339591ITGB4chr1773723586+ENST00000577200LLGL2chr1773552126+346445116334351090
ENST00000200181ITGB4chr1773723586+ENST00000167462LLGL2chr1773552126+372645116334231086
ENST00000200181ITGB4chr1773723586+ENST00000375227LLGL2chr1773552126+16264511631446427
ENST00000200181ITGB4chr1773723586+ENST00000392550LLGL2chr1773552126+376845116334381091
ENST00000200181ITGB4chr1773723586+ENST00000578363LLGL2chr1773552126+16284511631446427
ENST00000200181ITGB4chr1773723586+ENST00000577200LLGL2chr1773552126+346445116334351090
ENST00000450894ITGB4chr1773723586+ENST00000167462LLGL2chr1773552126+366539010233621086
ENST00000450894ITGB4chr1773723586+ENST00000375227LLGL2chr1773552126+15653901021385427
ENST00000450894ITGB4chr1773723586+ENST00000392550LLGL2chr1773552126+370739010233771091
ENST00000450894ITGB4chr1773723586+ENST00000578363LLGL2chr1773552126+15673901021385427
ENST00000450894ITGB4chr1773723586+ENST00000577200LLGL2chr1773552126+340339010233741090
ENST00000449880ITGB4chr1773723586+ENST00000167462LLGL2chr1773552126+3547272832441078
ENST00000449880ITGB4chr1773723586+ENST00000375227LLGL2chr1773552126+144727281267419
ENST00000449880ITGB4chr1773723586+ENST00000392550LLGL2chr1773552126+3589272832591083
ENST00000449880ITGB4chr1773723586+ENST00000578363LLGL2chr1773552126+144927281267419
ENST00000449880ITGB4chr1773723586+ENST00000577200LLGL2chr1773552126+3285272832561082

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000579662ENST00000167462ITGB4chr1773723586+LLGL2chr1773552127+0.0079956930.99200433
ENST00000579662ENST00000375227ITGB4chr1773723586+LLGL2chr1773552127+0.141874210.8581258
ENST00000579662ENST00000392550ITGB4chr1773723586+LLGL2chr1773552127+0.0074726230.99252737
ENST00000579662ENST00000578363ITGB4chr1773723586+LLGL2chr1773552127+0.14174110.8582589
ENST00000579662ENST00000577200ITGB4chr1773723586+LLGL2chr1773552127+0.0118253290.9881747
ENST00000339591ENST00000167462ITGB4chr1773723586+LLGL2chr1773552127+0.0081914040.9918086
ENST00000339591ENST00000375227ITGB4chr1773723586+LLGL2chr1773552127+0.138512660.8614873
ENST00000339591ENST00000392550ITGB4chr1773723586+LLGL2chr1773552127+0.0076544470.99234563
ENST00000339591ENST00000578363ITGB4chr1773723586+LLGL2chr1773552127+0.138276890.86172307
ENST00000339591ENST00000577200ITGB4chr1773723586+LLGL2chr1773552127+0.0123495110.98765045
ENST00000200181ENST00000167462ITGB4chr1773723586+LLGL2chr1773552127+0.0081914040.9918086
ENST00000200181ENST00000375227ITGB4chr1773723586+LLGL2chr1773552127+0.138512660.8614873
ENST00000200181ENST00000392550ITGB4chr1773723586+LLGL2chr1773552127+0.0076544470.99234563
ENST00000200181ENST00000578363ITGB4chr1773723586+LLGL2chr1773552127+0.138276890.86172307
ENST00000200181ENST00000577200ITGB4chr1773723586+LLGL2chr1773552127+0.0123495110.98765045
ENST00000450894ENST00000167462ITGB4chr1773723586+LLGL2chr1773552127+0.0078911930.99210876
ENST00000450894ENST00000375227ITGB4chr1773723586+LLGL2chr1773552127+0.129966040.8700339
ENST00000450894ENST00000392550ITGB4chr1773723586+LLGL2chr1773552127+0.0073619840.992638
ENST00000450894ENST00000578363ITGB4chr1773723586+LLGL2chr1773552127+0.129666330.8703336
ENST00000450894ENST00000577200ITGB4chr1773723586+LLGL2chr1773552127+0.0119535610.9880464
ENST00000449880ENST00000167462ITGB4chr1773723586+LLGL2chr1773552127+0.006875050.99312496
ENST00000449880ENST00000375227ITGB4chr1773723586+LLGL2chr1773552127+0.14961780.8503822
ENST00000449880ENST00000392550ITGB4chr1773723586+LLGL2chr1773552127+0.0064126110.9935874
ENST00000449880ENST00000578363ITGB4chr1773723586+LLGL2chr1773552127+0.148922340.8510777
ENST00000449880ENST00000577200ITGB4chr1773723586+LLGL2chr1773552127+0.0105410450.9894589
ENST00000579662ENST00000167462ITGB4chr1773723586+LLGL2chr1773552126+0.0079956930.99200433
ENST00000579662ENST00000375227ITGB4chr1773723586+LLGL2chr1773552126+0.141874210.8581258
ENST00000579662ENST00000392550ITGB4chr1773723586+LLGL2chr1773552126+0.0074726230.99252737
ENST00000579662ENST00000578363ITGB4chr1773723586+LLGL2chr1773552126+0.14174110.8582589
ENST00000579662ENST00000577200ITGB4chr1773723586+LLGL2chr1773552126+0.0118253290.9881747
ENST00000339591ENST00000167462ITGB4chr1773723586+LLGL2chr1773552126+0.0081914040.9918086
ENST00000339591ENST00000375227ITGB4chr1773723586+LLGL2chr1773552126+0.138512660.8614873
ENST00000339591ENST00000392550ITGB4chr1773723586+LLGL2chr1773552126+0.0076544470.99234563
ENST00000339591ENST00000578363ITGB4chr1773723586+LLGL2chr1773552126+0.138276890.86172307
ENST00000339591ENST00000577200ITGB4chr1773723586+LLGL2chr1773552126+0.0123495110.98765045
ENST00000200181ENST00000167462ITGB4chr1773723586+LLGL2chr1773552126+0.0081914040.9918086
ENST00000200181ENST00000375227ITGB4chr1773723586+LLGL2chr1773552126+0.138512660.8614873
ENST00000200181ENST00000392550ITGB4chr1773723586+LLGL2chr1773552126+0.0076544470.99234563
ENST00000200181ENST00000578363ITGB4chr1773723586+LLGL2chr1773552126+0.138276890.86172307
ENST00000200181ENST00000577200ITGB4chr1773723586+LLGL2chr1773552126+0.0123495110.98765045
ENST00000450894ENST00000167462ITGB4chr1773723586+LLGL2chr1773552126+0.0078911930.99210876
ENST00000450894ENST00000375227ITGB4chr1773723586+LLGL2chr1773552126+0.129966040.8700339
ENST00000450894ENST00000392550ITGB4chr1773723586+LLGL2chr1773552126+0.0073619840.992638
ENST00000450894ENST00000578363ITGB4chr1773723586+LLGL2chr1773552126+0.129666330.8703336
ENST00000450894ENST00000577200ITGB4chr1773723586+LLGL2chr1773552126+0.0119535610.9880464
ENST00000449880ENST00000167462ITGB4chr1773723586+LLGL2chr1773552126+0.006875050.99312496
ENST00000449880ENST00000375227ITGB4chr1773723586+LLGL2chr1773552126+0.14961780.8503822
ENST00000449880ENST00000392550ITGB4chr1773723586+LLGL2chr1773552126+0.0064126110.9935874
ENST00000449880ENST00000578363ITGB4chr1773723586+LLGL2chr1773552126+0.148922340.8510777
ENST00000449880ENST00000577200ITGB4chr1773723586+LLGL2chr1773552126+0.0105410450.9894589

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Fusion Amino Acid Sequences


check button For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

>40536_40536_1_ITGB4-LLGL2_ITGB4_chr17_73723586_ENST00000200181_LLGL2_chr17_73552126_ENST00000167462_length(amino acids)=1086AA_BP=96
MAGRGRKRMAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRRCNTQAELLAAGCQRESIVVMES
SFQITETVEHGFPHQPSALGYSPSLRILAIGTRSGAIKLYGAPGVEFMGLHQENNAVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGAS
ELQEDESFTLRGPPGAAPSATQITVVLPHSSCELLYLGTESGNVFVVQLPAFRALEDRTISSDAVLQRLPEEARHRRVFEMVEALQEHPR
DPNQILIGYSRGLVVIWDLQGSRVLYHFLSSQQLENIWWQRDGRLLVSCHSDGSYCQWPVSSEAQQPEPLRSLVPYGPFPCKAITRILWL
TTRQGLPFTIFQGGMPRASYGDRHCISVIHDGQQTAFDFTSRVIGFTVLTEADPAATFDDPYALVVLAEEELVVIDLQTAGWPPVQLPYL
ASLHCSAITCSHHVSNIPLKLWERIIAAGSRQNAHFSTMEWPIDGGTSLTPAPPQRDLLLTGHEDGTVRFWDASGVCLRLLYKLSTVRVF
LTDTDPNENFSAQGEDEWPPLRKVGSFDPYSDDPRLGIQKIFLCKYSGYLAVAGTAGQVLVLELNDEAAEQAVEQVEADLLQDQEGYRWK
GHERLAARSGPVRFEPGFQPFVLVQCQPPAVVTSLALHSEWRLVAFGTSHGFGLFDHQQRRQVFVKCTLHPSDQLALEGPLSRVKSLKKS
LRQSFRRMRRSRVSSRKRHPAGPPGEAQEGSAKAERPGLQNMELAPVQRKIEARSAEDSFTGFVRTLYFADTYLKDSSRHCPSLWAGTNG
GTIYAFSLRVPPAERRMDEPVRAEQAKEIQLMHRAPVVGILVLDGHSVPLPEPLEVAHDLSKSPDMQGSHQLLVVSEEQFKVFTLPKVSA
KLKLKLTALEGSRVRRVSVAHFGSRRAEDYGEHHLAVLTNLGDIQVVSLPLLKPQVRYSCIRREDVSGIASCVFTKYGQGFYLISPSEFE
RFSLSTKWLVEPRCLVDSAETKNHRPGNGAGPKKAPSRARNSGTQSDGEEKQPGLVMERALLSDERAATGVHIEPPWGAASAMAEQSEWL

--------------------------------------------------------------

>40536_40536_2_ITGB4-LLGL2_ITGB4_chr17_73723586_ENST00000200181_LLGL2_chr17_73552126_ENST00000375227_length(amino acids)=427AA_BP=96
MAGRGRKRMAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRRCNTQAELLAAGCQRESIVVMES
SFQITETVEHGFPHQPSALGYSPSLRILAIGTRSGAIKLYGAPGVEFMGLHQENNAVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGAS
ELQEDESFTLRGPPGAAPSATQITVVLPHSSCELLYLGTESGNVFVVQLPAFRALEDRTISSDAVLQRLPEEARHRRVFEMVEALQEHPR
DPNQILIGYSRGLVVIWDLQGSRVLYHFLSSQQLENIWWQRDGRLLVSCHSDGSYCQWPVSSEAQQPEPLRSLVPYGPFPCKAITRILWL

--------------------------------------------------------------

>40536_40536_3_ITGB4-LLGL2_ITGB4_chr17_73723586_ENST00000200181_LLGL2_chr17_73552126_ENST00000392550_length(amino acids)=1091AA_BP=96
MAGRGRKRMAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRRCNTQAELLAAGCQRESIVVMES
SFQITETVEHGFPHQPSALGYSPSLRILAIGTRSGAIKLYGAPGVEFMGLHQENNAVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGAS
ELQEDESFTLRGPPGAAPSATQITVVLPHSSCELLYLGTESGNVFVVQLPAFRALEDRTISSDAVLQRLPEEARHRRVFEMVEALQEHPR
DPNQILIGYSRGLVVIWDLQGSRVLYHFLSSQQLENIWWQRDGRLLVSCHSDGSYCQWPVSSEAQQPEPLRSLVPYGPFPCKAITRILWL
TTRQGLPFTIFQGGMPRASYGDRHCISVIHDGQQTAFDFTSRVIGFTVLTEADPAATFDDPYALVVLAEEELVVIDLQTAGWPPVQLPYL
ASLHCSAITCSHHVSNIPLKLWERIIAAGSRQNAHFSTMEWPIDGGTSLTPAPPQRDLLLTGHEDGTVRFWDASGVCLRLLYKLSTVRVF
LTDTDPNENFSAQGEDEWPPLRKVGSFDPYSDDPRLGIQKIFLCKYSGYLAVAGTAGQVLVLELNDEAAEQAVEQVEADLLQDQEGYRWK
GHERLAARSGPVRFEPGFQPFVLVQCQPPAVVTSLALHSEWRLVAFGTSHGFGLFDHQQRRQVFVKCTLHPSDQLALEGPLSRVKSLKKS
LRQSFRRMRRSRVSSRKRHPAGPPGEAQEGSAKAERPGLQNMELAPVQRKIEARSAEDSFTGFVRTLYFADTYLKDSSRHCPSLWAGTNG
GTIYAFSLRVPPAERRMDEPVRAEQAKEIQLMHRAPVVGILVLDGHSVPLPEPLEVAHDLSKSPDMQGSHQLLVVSEEQFKVFTLPKVSA
KLKLKLTALEGSRVRRVSVAHFGSRRAEDYGEHHLAVLTNLGDIQVVSLPLLKPQVRYSCIRREDVSGIASCVFTKYGQGFYLISPSEFE
RFSLSTKWLVEPRCLVDSAETKNHRPGNGAGPKKAPSRARNSGTQSDGEEKQPGLVMERALLSDERVLKEIQSTLEGDRGSGNWRSHRAA

--------------------------------------------------------------

>40536_40536_4_ITGB4-LLGL2_ITGB4_chr17_73723586_ENST00000200181_LLGL2_chr17_73552126_ENST00000577200_length(amino acids)=1090AA_BP=96
MAGRGRKRMAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRRCNTQAELLAAGCQRESIVVMES
SFQITETVEHGFPHQPSALGYSPSLRILAIGTRSGAIKLYGAPGVEFMGLHQENNAVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGAS
ELQEDESFTLRGPPGAAPSATQITVVLPHSSCELLYLGTESGNVFVVQLPAFRALEDRTISSDAVLQRLPEEARHRRVFEMVEALQEHPR
DPNQILIGYSRGLVVIWDLQGSRVLYHFLSSQQLENIWWQRDGRLLVSCHSDGSYCQWPVSSEAQQPEPLRSLVPYGPFPCKAITRILWL
TTRQGLPFTIFQGGMPRASYGDRHCISVIHDGQQTAFDFTSRVIGFTVLTEADPAATFDDPYALVVLAEEELVVIDLQTAGWPPVQLPYL
ASLHCSAITCSHHVSNIPLKLWERIIAAGSRQNAHFSTMEWPIDGGTSLTPAPPQRDLLLTGHEDGTVRFWDASGVCLRLLYKLSTVRVF
LTDTDPNENFSAQGEDEWPPLRKVGSFDPYSDDPRLGIQKIFLCKYSGYLAVAGTAGQVLVLELNDEAAEQAVEQVEADLLQDQEGYRWK
GHERLAARSGPVRFEPGFQPFVLVQCQPPAVVTSLALHSEWRLVAFGTSHGFGLFDHQQRRQVFVKCTLHPSDQLALEGPLSRVKSLKKS
LRQSFRRMRRSRVSSRKRHPAGPPGEAQEGSAKAERPGLQNMELAPVQRKIEARSAEDSFTGFVRTLYFADTYLKDSSRHCPSLWAGTNG
GTIYAFSLRVPPAERRMDEPVRAEQAKEIQLMHRAPVVGILVLDGHSVPLPEPLEVAHDLSKSPDMQGSHQLLVVSEEQFKVFTLPKVSA
KLKLKLTALEGSRVRRVSVAHFGSRRAEDYGEHHLAVLTNLGDIQVVSLPLLKPQVRYSCIRREDVSGIASCVFTKYGQGFYLISPSEFE
RFSLSTKWLVEPRCLVDSAETKNHRPGNGAGPKKAPSRARNSGTQSDGEEKQPGLVMERALLSDERVLKEIQSTLEGDRGSGNWRSHRAA

--------------------------------------------------------------

>40536_40536_5_ITGB4-LLGL2_ITGB4_chr17_73723586_ENST00000200181_LLGL2_chr17_73552126_ENST00000578363_length(amino acids)=427AA_BP=96
MAGRGRKRMAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRRCNTQAELLAAGCQRESIVVMES
SFQITETVEHGFPHQPSALGYSPSLRILAIGTRSGAIKLYGAPGVEFMGLHQENNAVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGAS
ELQEDESFTLRGPPGAAPSATQITVVLPHSSCELLYLGTESGNVFVVQLPAFRALEDRTISSDAVLQRLPEEARHRRVFEMVEALQEHPR
DPNQILIGYSRGLVVIWDLQGSRVLYHFLSSQQLENIWWQRDGRLLVSCHSDGSYCQWPVSSEAQQPEPLRSLVPYGPFPCKAITRILWL

--------------------------------------------------------------

>40536_40536_6_ITGB4-LLGL2_ITGB4_chr17_73723586_ENST00000200181_LLGL2_chr17_73552127_ENST00000167462_length(amino acids)=1086AA_BP=96
MAGRGRKRMAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRRCNTQAELLAAGCQRESIVVMES
SFQITETVEHGFPHQPSALGYSPSLRILAIGTRSGAIKLYGAPGVEFMGLHQENNAVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGAS
ELQEDESFTLRGPPGAAPSATQITVVLPHSSCELLYLGTESGNVFVVQLPAFRALEDRTISSDAVLQRLPEEARHRRVFEMVEALQEHPR
DPNQILIGYSRGLVVIWDLQGSRVLYHFLSSQQLENIWWQRDGRLLVSCHSDGSYCQWPVSSEAQQPEPLRSLVPYGPFPCKAITRILWL
TTRQGLPFTIFQGGMPRASYGDRHCISVIHDGQQTAFDFTSRVIGFTVLTEADPAATFDDPYALVVLAEEELVVIDLQTAGWPPVQLPYL
ASLHCSAITCSHHVSNIPLKLWERIIAAGSRQNAHFSTMEWPIDGGTSLTPAPPQRDLLLTGHEDGTVRFWDASGVCLRLLYKLSTVRVF
LTDTDPNENFSAQGEDEWPPLRKVGSFDPYSDDPRLGIQKIFLCKYSGYLAVAGTAGQVLVLELNDEAAEQAVEQVEADLLQDQEGYRWK
GHERLAARSGPVRFEPGFQPFVLVQCQPPAVVTSLALHSEWRLVAFGTSHGFGLFDHQQRRQVFVKCTLHPSDQLALEGPLSRVKSLKKS
LRQSFRRMRRSRVSSRKRHPAGPPGEAQEGSAKAERPGLQNMELAPVQRKIEARSAEDSFTGFVRTLYFADTYLKDSSRHCPSLWAGTNG
GTIYAFSLRVPPAERRMDEPVRAEQAKEIQLMHRAPVVGILVLDGHSVPLPEPLEVAHDLSKSPDMQGSHQLLVVSEEQFKVFTLPKVSA
KLKLKLTALEGSRVRRVSVAHFGSRRAEDYGEHHLAVLTNLGDIQVVSLPLLKPQVRYSCIRREDVSGIASCVFTKYGQGFYLISPSEFE
RFSLSTKWLVEPRCLVDSAETKNHRPGNGAGPKKAPSRARNSGTQSDGEEKQPGLVMERALLSDERAATGVHIEPPWGAASAMAEQSEWL

--------------------------------------------------------------

>40536_40536_7_ITGB4-LLGL2_ITGB4_chr17_73723586_ENST00000200181_LLGL2_chr17_73552127_ENST00000375227_length(amino acids)=427AA_BP=96
MAGRGRKRMAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRRCNTQAELLAAGCQRESIVVMES
SFQITETVEHGFPHQPSALGYSPSLRILAIGTRSGAIKLYGAPGVEFMGLHQENNAVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGAS
ELQEDESFTLRGPPGAAPSATQITVVLPHSSCELLYLGTESGNVFVVQLPAFRALEDRTISSDAVLQRLPEEARHRRVFEMVEALQEHPR
DPNQILIGYSRGLVVIWDLQGSRVLYHFLSSQQLENIWWQRDGRLLVSCHSDGSYCQWPVSSEAQQPEPLRSLVPYGPFPCKAITRILWL

--------------------------------------------------------------

>40536_40536_8_ITGB4-LLGL2_ITGB4_chr17_73723586_ENST00000200181_LLGL2_chr17_73552127_ENST00000392550_length(amino acids)=1091AA_BP=96
MAGRGRKRMAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRRCNTQAELLAAGCQRESIVVMES
SFQITETVEHGFPHQPSALGYSPSLRILAIGTRSGAIKLYGAPGVEFMGLHQENNAVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGAS
ELQEDESFTLRGPPGAAPSATQITVVLPHSSCELLYLGTESGNVFVVQLPAFRALEDRTISSDAVLQRLPEEARHRRVFEMVEALQEHPR
DPNQILIGYSRGLVVIWDLQGSRVLYHFLSSQQLENIWWQRDGRLLVSCHSDGSYCQWPVSSEAQQPEPLRSLVPYGPFPCKAITRILWL
TTRQGLPFTIFQGGMPRASYGDRHCISVIHDGQQTAFDFTSRVIGFTVLTEADPAATFDDPYALVVLAEEELVVIDLQTAGWPPVQLPYL
ASLHCSAITCSHHVSNIPLKLWERIIAAGSRQNAHFSTMEWPIDGGTSLTPAPPQRDLLLTGHEDGTVRFWDASGVCLRLLYKLSTVRVF
LTDTDPNENFSAQGEDEWPPLRKVGSFDPYSDDPRLGIQKIFLCKYSGYLAVAGTAGQVLVLELNDEAAEQAVEQVEADLLQDQEGYRWK
GHERLAARSGPVRFEPGFQPFVLVQCQPPAVVTSLALHSEWRLVAFGTSHGFGLFDHQQRRQVFVKCTLHPSDQLALEGPLSRVKSLKKS
LRQSFRRMRRSRVSSRKRHPAGPPGEAQEGSAKAERPGLQNMELAPVQRKIEARSAEDSFTGFVRTLYFADTYLKDSSRHCPSLWAGTNG
GTIYAFSLRVPPAERRMDEPVRAEQAKEIQLMHRAPVVGILVLDGHSVPLPEPLEVAHDLSKSPDMQGSHQLLVVSEEQFKVFTLPKVSA
KLKLKLTALEGSRVRRVSVAHFGSRRAEDYGEHHLAVLTNLGDIQVVSLPLLKPQVRYSCIRREDVSGIASCVFTKYGQGFYLISPSEFE
RFSLSTKWLVEPRCLVDSAETKNHRPGNGAGPKKAPSRARNSGTQSDGEEKQPGLVMERALLSDERVLKEIQSTLEGDRGSGNWRSHRAA

--------------------------------------------------------------

>40536_40536_9_ITGB4-LLGL2_ITGB4_chr17_73723586_ENST00000200181_LLGL2_chr17_73552127_ENST00000577200_length(amino acids)=1090AA_BP=96
MAGRGRKRMAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRRCNTQAELLAAGCQRESIVVMES
SFQITETVEHGFPHQPSALGYSPSLRILAIGTRSGAIKLYGAPGVEFMGLHQENNAVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGAS
ELQEDESFTLRGPPGAAPSATQITVVLPHSSCELLYLGTESGNVFVVQLPAFRALEDRTISSDAVLQRLPEEARHRRVFEMVEALQEHPR
DPNQILIGYSRGLVVIWDLQGSRVLYHFLSSQQLENIWWQRDGRLLVSCHSDGSYCQWPVSSEAQQPEPLRSLVPYGPFPCKAITRILWL
TTRQGLPFTIFQGGMPRASYGDRHCISVIHDGQQTAFDFTSRVIGFTVLTEADPAATFDDPYALVVLAEEELVVIDLQTAGWPPVQLPYL
ASLHCSAITCSHHVSNIPLKLWERIIAAGSRQNAHFSTMEWPIDGGTSLTPAPPQRDLLLTGHEDGTVRFWDASGVCLRLLYKLSTVRVF
LTDTDPNENFSAQGEDEWPPLRKVGSFDPYSDDPRLGIQKIFLCKYSGYLAVAGTAGQVLVLELNDEAAEQAVEQVEADLLQDQEGYRWK
GHERLAARSGPVRFEPGFQPFVLVQCQPPAVVTSLALHSEWRLVAFGTSHGFGLFDHQQRRQVFVKCTLHPSDQLALEGPLSRVKSLKKS
LRQSFRRMRRSRVSSRKRHPAGPPGEAQEGSAKAERPGLQNMELAPVQRKIEARSAEDSFTGFVRTLYFADTYLKDSSRHCPSLWAGTNG
GTIYAFSLRVPPAERRMDEPVRAEQAKEIQLMHRAPVVGILVLDGHSVPLPEPLEVAHDLSKSPDMQGSHQLLVVSEEQFKVFTLPKVSA
KLKLKLTALEGSRVRRVSVAHFGSRRAEDYGEHHLAVLTNLGDIQVVSLPLLKPQVRYSCIRREDVSGIASCVFTKYGQGFYLISPSEFE
RFSLSTKWLVEPRCLVDSAETKNHRPGNGAGPKKAPSRARNSGTQSDGEEKQPGLVMERALLSDERVLKEIQSTLEGDRGSGNWRSHRAA

--------------------------------------------------------------

>40536_40536_10_ITGB4-LLGL2_ITGB4_chr17_73723586_ENST00000200181_LLGL2_chr17_73552127_ENST00000578363_length(amino acids)=427AA_BP=96
MAGRGRKRMAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRRCNTQAELLAAGCQRESIVVMES
SFQITETVEHGFPHQPSALGYSPSLRILAIGTRSGAIKLYGAPGVEFMGLHQENNAVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGAS
ELQEDESFTLRGPPGAAPSATQITVVLPHSSCELLYLGTESGNVFVVQLPAFRALEDRTISSDAVLQRLPEEARHRRVFEMVEALQEHPR
DPNQILIGYSRGLVVIWDLQGSRVLYHFLSSQQLENIWWQRDGRLLVSCHSDGSYCQWPVSSEAQQPEPLRSLVPYGPFPCKAITRILWL

--------------------------------------------------------------

>40536_40536_11_ITGB4-LLGL2_ITGB4_chr17_73723586_ENST00000339591_LLGL2_chr17_73552126_ENST00000167462_length(amino acids)=1086AA_BP=96
MAGRGRKRMAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRRCNTQAELLAAGCQRESIVVMES
SFQITETVEHGFPHQPSALGYSPSLRILAIGTRSGAIKLYGAPGVEFMGLHQENNAVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGAS
ELQEDESFTLRGPPGAAPSATQITVVLPHSSCELLYLGTESGNVFVVQLPAFRALEDRTISSDAVLQRLPEEARHRRVFEMVEALQEHPR
DPNQILIGYSRGLVVIWDLQGSRVLYHFLSSQQLENIWWQRDGRLLVSCHSDGSYCQWPVSSEAQQPEPLRSLVPYGPFPCKAITRILWL
TTRQGLPFTIFQGGMPRASYGDRHCISVIHDGQQTAFDFTSRVIGFTVLTEADPAATFDDPYALVVLAEEELVVIDLQTAGWPPVQLPYL
ASLHCSAITCSHHVSNIPLKLWERIIAAGSRQNAHFSTMEWPIDGGTSLTPAPPQRDLLLTGHEDGTVRFWDASGVCLRLLYKLSTVRVF
LTDTDPNENFSAQGEDEWPPLRKVGSFDPYSDDPRLGIQKIFLCKYSGYLAVAGTAGQVLVLELNDEAAEQAVEQVEADLLQDQEGYRWK
GHERLAARSGPVRFEPGFQPFVLVQCQPPAVVTSLALHSEWRLVAFGTSHGFGLFDHQQRRQVFVKCTLHPSDQLALEGPLSRVKSLKKS
LRQSFRRMRRSRVSSRKRHPAGPPGEAQEGSAKAERPGLQNMELAPVQRKIEARSAEDSFTGFVRTLYFADTYLKDSSRHCPSLWAGTNG
GTIYAFSLRVPPAERRMDEPVRAEQAKEIQLMHRAPVVGILVLDGHSVPLPEPLEVAHDLSKSPDMQGSHQLLVVSEEQFKVFTLPKVSA
KLKLKLTALEGSRVRRVSVAHFGSRRAEDYGEHHLAVLTNLGDIQVVSLPLLKPQVRYSCIRREDVSGIASCVFTKYGQGFYLISPSEFE
RFSLSTKWLVEPRCLVDSAETKNHRPGNGAGPKKAPSRARNSGTQSDGEEKQPGLVMERALLSDERAATGVHIEPPWGAASAMAEQSEWL

--------------------------------------------------------------

>40536_40536_12_ITGB4-LLGL2_ITGB4_chr17_73723586_ENST00000339591_LLGL2_chr17_73552126_ENST00000375227_length(amino acids)=427AA_BP=96
MAGRGRKRMAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRRCNTQAELLAAGCQRESIVVMES
SFQITETVEHGFPHQPSALGYSPSLRILAIGTRSGAIKLYGAPGVEFMGLHQENNAVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGAS
ELQEDESFTLRGPPGAAPSATQITVVLPHSSCELLYLGTESGNVFVVQLPAFRALEDRTISSDAVLQRLPEEARHRRVFEMVEALQEHPR
DPNQILIGYSRGLVVIWDLQGSRVLYHFLSSQQLENIWWQRDGRLLVSCHSDGSYCQWPVSSEAQQPEPLRSLVPYGPFPCKAITRILWL

--------------------------------------------------------------

>40536_40536_13_ITGB4-LLGL2_ITGB4_chr17_73723586_ENST00000339591_LLGL2_chr17_73552126_ENST00000392550_length(amino acids)=1091AA_BP=96
MAGRGRKRMAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRRCNTQAELLAAGCQRESIVVMES
SFQITETVEHGFPHQPSALGYSPSLRILAIGTRSGAIKLYGAPGVEFMGLHQENNAVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGAS
ELQEDESFTLRGPPGAAPSATQITVVLPHSSCELLYLGTESGNVFVVQLPAFRALEDRTISSDAVLQRLPEEARHRRVFEMVEALQEHPR
DPNQILIGYSRGLVVIWDLQGSRVLYHFLSSQQLENIWWQRDGRLLVSCHSDGSYCQWPVSSEAQQPEPLRSLVPYGPFPCKAITRILWL
TTRQGLPFTIFQGGMPRASYGDRHCISVIHDGQQTAFDFTSRVIGFTVLTEADPAATFDDPYALVVLAEEELVVIDLQTAGWPPVQLPYL
ASLHCSAITCSHHVSNIPLKLWERIIAAGSRQNAHFSTMEWPIDGGTSLTPAPPQRDLLLTGHEDGTVRFWDASGVCLRLLYKLSTVRVF
LTDTDPNENFSAQGEDEWPPLRKVGSFDPYSDDPRLGIQKIFLCKYSGYLAVAGTAGQVLVLELNDEAAEQAVEQVEADLLQDQEGYRWK
GHERLAARSGPVRFEPGFQPFVLVQCQPPAVVTSLALHSEWRLVAFGTSHGFGLFDHQQRRQVFVKCTLHPSDQLALEGPLSRVKSLKKS
LRQSFRRMRRSRVSSRKRHPAGPPGEAQEGSAKAERPGLQNMELAPVQRKIEARSAEDSFTGFVRTLYFADTYLKDSSRHCPSLWAGTNG
GTIYAFSLRVPPAERRMDEPVRAEQAKEIQLMHRAPVVGILVLDGHSVPLPEPLEVAHDLSKSPDMQGSHQLLVVSEEQFKVFTLPKVSA
KLKLKLTALEGSRVRRVSVAHFGSRRAEDYGEHHLAVLTNLGDIQVVSLPLLKPQVRYSCIRREDVSGIASCVFTKYGQGFYLISPSEFE
RFSLSTKWLVEPRCLVDSAETKNHRPGNGAGPKKAPSRARNSGTQSDGEEKQPGLVMERALLSDERVLKEIQSTLEGDRGSGNWRSHRAA

--------------------------------------------------------------

>40536_40536_14_ITGB4-LLGL2_ITGB4_chr17_73723586_ENST00000339591_LLGL2_chr17_73552126_ENST00000577200_length(amino acids)=1090AA_BP=96
MAGRGRKRMAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRRCNTQAELLAAGCQRESIVVMES
SFQITETVEHGFPHQPSALGYSPSLRILAIGTRSGAIKLYGAPGVEFMGLHQENNAVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGAS
ELQEDESFTLRGPPGAAPSATQITVVLPHSSCELLYLGTESGNVFVVQLPAFRALEDRTISSDAVLQRLPEEARHRRVFEMVEALQEHPR
DPNQILIGYSRGLVVIWDLQGSRVLYHFLSSQQLENIWWQRDGRLLVSCHSDGSYCQWPVSSEAQQPEPLRSLVPYGPFPCKAITRILWL
TTRQGLPFTIFQGGMPRASYGDRHCISVIHDGQQTAFDFTSRVIGFTVLTEADPAATFDDPYALVVLAEEELVVIDLQTAGWPPVQLPYL
ASLHCSAITCSHHVSNIPLKLWERIIAAGSRQNAHFSTMEWPIDGGTSLTPAPPQRDLLLTGHEDGTVRFWDASGVCLRLLYKLSTVRVF
LTDTDPNENFSAQGEDEWPPLRKVGSFDPYSDDPRLGIQKIFLCKYSGYLAVAGTAGQVLVLELNDEAAEQAVEQVEADLLQDQEGYRWK
GHERLAARSGPVRFEPGFQPFVLVQCQPPAVVTSLALHSEWRLVAFGTSHGFGLFDHQQRRQVFVKCTLHPSDQLALEGPLSRVKSLKKS
LRQSFRRMRRSRVSSRKRHPAGPPGEAQEGSAKAERPGLQNMELAPVQRKIEARSAEDSFTGFVRTLYFADTYLKDSSRHCPSLWAGTNG
GTIYAFSLRVPPAERRMDEPVRAEQAKEIQLMHRAPVVGILVLDGHSVPLPEPLEVAHDLSKSPDMQGSHQLLVVSEEQFKVFTLPKVSA
KLKLKLTALEGSRVRRVSVAHFGSRRAEDYGEHHLAVLTNLGDIQVVSLPLLKPQVRYSCIRREDVSGIASCVFTKYGQGFYLISPSEFE
RFSLSTKWLVEPRCLVDSAETKNHRPGNGAGPKKAPSRARNSGTQSDGEEKQPGLVMERALLSDERVLKEIQSTLEGDRGSGNWRSHRAA

--------------------------------------------------------------

>40536_40536_15_ITGB4-LLGL2_ITGB4_chr17_73723586_ENST00000339591_LLGL2_chr17_73552126_ENST00000578363_length(amino acids)=427AA_BP=96
MAGRGRKRMAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRRCNTQAELLAAGCQRESIVVMES
SFQITETVEHGFPHQPSALGYSPSLRILAIGTRSGAIKLYGAPGVEFMGLHQENNAVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGAS
ELQEDESFTLRGPPGAAPSATQITVVLPHSSCELLYLGTESGNVFVVQLPAFRALEDRTISSDAVLQRLPEEARHRRVFEMVEALQEHPR
DPNQILIGYSRGLVVIWDLQGSRVLYHFLSSQQLENIWWQRDGRLLVSCHSDGSYCQWPVSSEAQQPEPLRSLVPYGPFPCKAITRILWL

--------------------------------------------------------------

>40536_40536_16_ITGB4-LLGL2_ITGB4_chr17_73723586_ENST00000339591_LLGL2_chr17_73552127_ENST00000167462_length(amino acids)=1086AA_BP=96
MAGRGRKRMAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRRCNTQAELLAAGCQRESIVVMES
SFQITETVEHGFPHQPSALGYSPSLRILAIGTRSGAIKLYGAPGVEFMGLHQENNAVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGAS
ELQEDESFTLRGPPGAAPSATQITVVLPHSSCELLYLGTESGNVFVVQLPAFRALEDRTISSDAVLQRLPEEARHRRVFEMVEALQEHPR
DPNQILIGYSRGLVVIWDLQGSRVLYHFLSSQQLENIWWQRDGRLLVSCHSDGSYCQWPVSSEAQQPEPLRSLVPYGPFPCKAITRILWL
TTRQGLPFTIFQGGMPRASYGDRHCISVIHDGQQTAFDFTSRVIGFTVLTEADPAATFDDPYALVVLAEEELVVIDLQTAGWPPVQLPYL
ASLHCSAITCSHHVSNIPLKLWERIIAAGSRQNAHFSTMEWPIDGGTSLTPAPPQRDLLLTGHEDGTVRFWDASGVCLRLLYKLSTVRVF
LTDTDPNENFSAQGEDEWPPLRKVGSFDPYSDDPRLGIQKIFLCKYSGYLAVAGTAGQVLVLELNDEAAEQAVEQVEADLLQDQEGYRWK
GHERLAARSGPVRFEPGFQPFVLVQCQPPAVVTSLALHSEWRLVAFGTSHGFGLFDHQQRRQVFVKCTLHPSDQLALEGPLSRVKSLKKS
LRQSFRRMRRSRVSSRKRHPAGPPGEAQEGSAKAERPGLQNMELAPVQRKIEARSAEDSFTGFVRTLYFADTYLKDSSRHCPSLWAGTNG
GTIYAFSLRVPPAERRMDEPVRAEQAKEIQLMHRAPVVGILVLDGHSVPLPEPLEVAHDLSKSPDMQGSHQLLVVSEEQFKVFTLPKVSA
KLKLKLTALEGSRVRRVSVAHFGSRRAEDYGEHHLAVLTNLGDIQVVSLPLLKPQVRYSCIRREDVSGIASCVFTKYGQGFYLISPSEFE
RFSLSTKWLVEPRCLVDSAETKNHRPGNGAGPKKAPSRARNSGTQSDGEEKQPGLVMERALLSDERAATGVHIEPPWGAASAMAEQSEWL

--------------------------------------------------------------

>40536_40536_17_ITGB4-LLGL2_ITGB4_chr17_73723586_ENST00000339591_LLGL2_chr17_73552127_ENST00000375227_length(amino acids)=427AA_BP=96
MAGRGRKRMAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRRCNTQAELLAAGCQRESIVVMES
SFQITETVEHGFPHQPSALGYSPSLRILAIGTRSGAIKLYGAPGVEFMGLHQENNAVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGAS
ELQEDESFTLRGPPGAAPSATQITVVLPHSSCELLYLGTESGNVFVVQLPAFRALEDRTISSDAVLQRLPEEARHRRVFEMVEALQEHPR
DPNQILIGYSRGLVVIWDLQGSRVLYHFLSSQQLENIWWQRDGRLLVSCHSDGSYCQWPVSSEAQQPEPLRSLVPYGPFPCKAITRILWL

--------------------------------------------------------------

>40536_40536_18_ITGB4-LLGL2_ITGB4_chr17_73723586_ENST00000339591_LLGL2_chr17_73552127_ENST00000392550_length(amino acids)=1091AA_BP=96
MAGRGRKRMAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRRCNTQAELLAAGCQRESIVVMES
SFQITETVEHGFPHQPSALGYSPSLRILAIGTRSGAIKLYGAPGVEFMGLHQENNAVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGAS
ELQEDESFTLRGPPGAAPSATQITVVLPHSSCELLYLGTESGNVFVVQLPAFRALEDRTISSDAVLQRLPEEARHRRVFEMVEALQEHPR
DPNQILIGYSRGLVVIWDLQGSRVLYHFLSSQQLENIWWQRDGRLLVSCHSDGSYCQWPVSSEAQQPEPLRSLVPYGPFPCKAITRILWL
TTRQGLPFTIFQGGMPRASYGDRHCISVIHDGQQTAFDFTSRVIGFTVLTEADPAATFDDPYALVVLAEEELVVIDLQTAGWPPVQLPYL
ASLHCSAITCSHHVSNIPLKLWERIIAAGSRQNAHFSTMEWPIDGGTSLTPAPPQRDLLLTGHEDGTVRFWDASGVCLRLLYKLSTVRVF
LTDTDPNENFSAQGEDEWPPLRKVGSFDPYSDDPRLGIQKIFLCKYSGYLAVAGTAGQVLVLELNDEAAEQAVEQVEADLLQDQEGYRWK
GHERLAARSGPVRFEPGFQPFVLVQCQPPAVVTSLALHSEWRLVAFGTSHGFGLFDHQQRRQVFVKCTLHPSDQLALEGPLSRVKSLKKS
LRQSFRRMRRSRVSSRKRHPAGPPGEAQEGSAKAERPGLQNMELAPVQRKIEARSAEDSFTGFVRTLYFADTYLKDSSRHCPSLWAGTNG
GTIYAFSLRVPPAERRMDEPVRAEQAKEIQLMHRAPVVGILVLDGHSVPLPEPLEVAHDLSKSPDMQGSHQLLVVSEEQFKVFTLPKVSA
KLKLKLTALEGSRVRRVSVAHFGSRRAEDYGEHHLAVLTNLGDIQVVSLPLLKPQVRYSCIRREDVSGIASCVFTKYGQGFYLISPSEFE
RFSLSTKWLVEPRCLVDSAETKNHRPGNGAGPKKAPSRARNSGTQSDGEEKQPGLVMERALLSDERVLKEIQSTLEGDRGSGNWRSHRAA

--------------------------------------------------------------

>40536_40536_19_ITGB4-LLGL2_ITGB4_chr17_73723586_ENST00000339591_LLGL2_chr17_73552127_ENST00000577200_length(amino acids)=1090AA_BP=96
MAGRGRKRMAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRRCNTQAELLAAGCQRESIVVMES
SFQITETVEHGFPHQPSALGYSPSLRILAIGTRSGAIKLYGAPGVEFMGLHQENNAVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGAS
ELQEDESFTLRGPPGAAPSATQITVVLPHSSCELLYLGTESGNVFVVQLPAFRALEDRTISSDAVLQRLPEEARHRRVFEMVEALQEHPR
DPNQILIGYSRGLVVIWDLQGSRVLYHFLSSQQLENIWWQRDGRLLVSCHSDGSYCQWPVSSEAQQPEPLRSLVPYGPFPCKAITRILWL
TTRQGLPFTIFQGGMPRASYGDRHCISVIHDGQQTAFDFTSRVIGFTVLTEADPAATFDDPYALVVLAEEELVVIDLQTAGWPPVQLPYL
ASLHCSAITCSHHVSNIPLKLWERIIAAGSRQNAHFSTMEWPIDGGTSLTPAPPQRDLLLTGHEDGTVRFWDASGVCLRLLYKLSTVRVF
LTDTDPNENFSAQGEDEWPPLRKVGSFDPYSDDPRLGIQKIFLCKYSGYLAVAGTAGQVLVLELNDEAAEQAVEQVEADLLQDQEGYRWK
GHERLAARSGPVRFEPGFQPFVLVQCQPPAVVTSLALHSEWRLVAFGTSHGFGLFDHQQRRQVFVKCTLHPSDQLALEGPLSRVKSLKKS
LRQSFRRMRRSRVSSRKRHPAGPPGEAQEGSAKAERPGLQNMELAPVQRKIEARSAEDSFTGFVRTLYFADTYLKDSSRHCPSLWAGTNG
GTIYAFSLRVPPAERRMDEPVRAEQAKEIQLMHRAPVVGILVLDGHSVPLPEPLEVAHDLSKSPDMQGSHQLLVVSEEQFKVFTLPKVSA
KLKLKLTALEGSRVRRVSVAHFGSRRAEDYGEHHLAVLTNLGDIQVVSLPLLKPQVRYSCIRREDVSGIASCVFTKYGQGFYLISPSEFE
RFSLSTKWLVEPRCLVDSAETKNHRPGNGAGPKKAPSRARNSGTQSDGEEKQPGLVMERALLSDERVLKEIQSTLEGDRGSGNWRSHRAA

--------------------------------------------------------------

>40536_40536_20_ITGB4-LLGL2_ITGB4_chr17_73723586_ENST00000339591_LLGL2_chr17_73552127_ENST00000578363_length(amino acids)=427AA_BP=96
MAGRGRKRMAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRRCNTQAELLAAGCQRESIVVMES
SFQITETVEHGFPHQPSALGYSPSLRILAIGTRSGAIKLYGAPGVEFMGLHQENNAVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGAS
ELQEDESFTLRGPPGAAPSATQITVVLPHSSCELLYLGTESGNVFVVQLPAFRALEDRTISSDAVLQRLPEEARHRRVFEMVEALQEHPR
DPNQILIGYSRGLVVIWDLQGSRVLYHFLSSQQLENIWWQRDGRLLVSCHSDGSYCQWPVSSEAQQPEPLRSLVPYGPFPCKAITRILWL

--------------------------------------------------------------

>40536_40536_21_ITGB4-LLGL2_ITGB4_chr17_73723586_ENST00000449880_LLGL2_chr17_73552126_ENST00000167462_length(amino acids)=1078AA_BP=88
MAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRRCNTQAELLAAGCQRESIVVMESSFQITETV
EHGFPHQPSALGYSPSLRILAIGTRSGAIKLYGAPGVEFMGLHQENNAVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGASELQEDESF
TLRGPPGAAPSATQITVVLPHSSCELLYLGTESGNVFVVQLPAFRALEDRTISSDAVLQRLPEEARHRRVFEMVEALQEHPRDPNQILIG
YSRGLVVIWDLQGSRVLYHFLSSQQLENIWWQRDGRLLVSCHSDGSYCQWPVSSEAQQPEPLRSLVPYGPFPCKAITRILWLTTRQGLPF
TIFQGGMPRASYGDRHCISVIHDGQQTAFDFTSRVIGFTVLTEADPAATFDDPYALVVLAEEELVVIDLQTAGWPPVQLPYLASLHCSAI
TCSHHVSNIPLKLWERIIAAGSRQNAHFSTMEWPIDGGTSLTPAPPQRDLLLTGHEDGTVRFWDASGVCLRLLYKLSTVRVFLTDTDPNE
NFSAQGEDEWPPLRKVGSFDPYSDDPRLGIQKIFLCKYSGYLAVAGTAGQVLVLELNDEAAEQAVEQVEADLLQDQEGYRWKGHERLAAR
SGPVRFEPGFQPFVLVQCQPPAVVTSLALHSEWRLVAFGTSHGFGLFDHQQRRQVFVKCTLHPSDQLALEGPLSRVKSLKKSLRQSFRRM
RRSRVSSRKRHPAGPPGEAQEGSAKAERPGLQNMELAPVQRKIEARSAEDSFTGFVRTLYFADTYLKDSSRHCPSLWAGTNGGTIYAFSL
RVPPAERRMDEPVRAEQAKEIQLMHRAPVVGILVLDGHSVPLPEPLEVAHDLSKSPDMQGSHQLLVVSEEQFKVFTLPKVSAKLKLKLTA
LEGSRVRRVSVAHFGSRRAEDYGEHHLAVLTNLGDIQVVSLPLLKPQVRYSCIRREDVSGIASCVFTKYGQGFYLISPSEFERFSLSTKW

--------------------------------------------------------------

>40536_40536_22_ITGB4-LLGL2_ITGB4_chr17_73723586_ENST00000449880_LLGL2_chr17_73552126_ENST00000375227_length(amino acids)=419AA_BP=88
MAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRRCNTQAELLAAGCQRESIVVMESSFQITETV
EHGFPHQPSALGYSPSLRILAIGTRSGAIKLYGAPGVEFMGLHQENNAVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGASELQEDESF
TLRGPPGAAPSATQITVVLPHSSCELLYLGTESGNVFVVQLPAFRALEDRTISSDAVLQRLPEEARHRRVFEMVEALQEHPRDPNQILIG
YSRGLVVIWDLQGSRVLYHFLSSQQLENIWWQRDGRLLVSCHSDGSYCQWPVSSEAQQPEPLRSLVPYGPFPCKAITRILWLTTRQGLPF

--------------------------------------------------------------

>40536_40536_23_ITGB4-LLGL2_ITGB4_chr17_73723586_ENST00000449880_LLGL2_chr17_73552126_ENST00000392550_length(amino acids)=1083AA_BP=88
MAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRRCNTQAELLAAGCQRESIVVMESSFQITETV
EHGFPHQPSALGYSPSLRILAIGTRSGAIKLYGAPGVEFMGLHQENNAVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGASELQEDESF
TLRGPPGAAPSATQITVVLPHSSCELLYLGTESGNVFVVQLPAFRALEDRTISSDAVLQRLPEEARHRRVFEMVEALQEHPRDPNQILIG
YSRGLVVIWDLQGSRVLYHFLSSQQLENIWWQRDGRLLVSCHSDGSYCQWPVSSEAQQPEPLRSLVPYGPFPCKAITRILWLTTRQGLPF
TIFQGGMPRASYGDRHCISVIHDGQQTAFDFTSRVIGFTVLTEADPAATFDDPYALVVLAEEELVVIDLQTAGWPPVQLPYLASLHCSAI
TCSHHVSNIPLKLWERIIAAGSRQNAHFSTMEWPIDGGTSLTPAPPQRDLLLTGHEDGTVRFWDASGVCLRLLYKLSTVRVFLTDTDPNE
NFSAQGEDEWPPLRKVGSFDPYSDDPRLGIQKIFLCKYSGYLAVAGTAGQVLVLELNDEAAEQAVEQVEADLLQDQEGYRWKGHERLAAR
SGPVRFEPGFQPFVLVQCQPPAVVTSLALHSEWRLVAFGTSHGFGLFDHQQRRQVFVKCTLHPSDQLALEGPLSRVKSLKKSLRQSFRRM
RRSRVSSRKRHPAGPPGEAQEGSAKAERPGLQNMELAPVQRKIEARSAEDSFTGFVRTLYFADTYLKDSSRHCPSLWAGTNGGTIYAFSL
RVPPAERRMDEPVRAEQAKEIQLMHRAPVVGILVLDGHSVPLPEPLEVAHDLSKSPDMQGSHQLLVVSEEQFKVFTLPKVSAKLKLKLTA
LEGSRVRRVSVAHFGSRRAEDYGEHHLAVLTNLGDIQVVSLPLLKPQVRYSCIRREDVSGIASCVFTKYGQGFYLISPSEFERFSLSTKW
LVEPRCLVDSAETKNHRPGNGAGPKKAPSRARNSGTQSDGEEKQPGLVMERALLSDERVLKEIQSTLEGDRGSGNWRSHRAAVGCSLSNG

--------------------------------------------------------------

>40536_40536_24_ITGB4-LLGL2_ITGB4_chr17_73723586_ENST00000449880_LLGL2_chr17_73552126_ENST00000577200_length(amino acids)=1082AA_BP=88
MAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRRCNTQAELLAAGCQRESIVVMESSFQITETV
EHGFPHQPSALGYSPSLRILAIGTRSGAIKLYGAPGVEFMGLHQENNAVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGASELQEDESF
TLRGPPGAAPSATQITVVLPHSSCELLYLGTESGNVFVVQLPAFRALEDRTISSDAVLQRLPEEARHRRVFEMVEALQEHPRDPNQILIG
YSRGLVVIWDLQGSRVLYHFLSSQQLENIWWQRDGRLLVSCHSDGSYCQWPVSSEAQQPEPLRSLVPYGPFPCKAITRILWLTTRQGLPF
TIFQGGMPRASYGDRHCISVIHDGQQTAFDFTSRVIGFTVLTEADPAATFDDPYALVVLAEEELVVIDLQTAGWPPVQLPYLASLHCSAI
TCSHHVSNIPLKLWERIIAAGSRQNAHFSTMEWPIDGGTSLTPAPPQRDLLLTGHEDGTVRFWDASGVCLRLLYKLSTVRVFLTDTDPNE
NFSAQGEDEWPPLRKVGSFDPYSDDPRLGIQKIFLCKYSGYLAVAGTAGQVLVLELNDEAAEQAVEQVEADLLQDQEGYRWKGHERLAAR
SGPVRFEPGFQPFVLVQCQPPAVVTSLALHSEWRLVAFGTSHGFGLFDHQQRRQVFVKCTLHPSDQLALEGPLSRVKSLKKSLRQSFRRM
RRSRVSSRKRHPAGPPGEAQEGSAKAERPGLQNMELAPVQRKIEARSAEDSFTGFVRTLYFADTYLKDSSRHCPSLWAGTNGGTIYAFSL
RVPPAERRMDEPVRAEQAKEIQLMHRAPVVGILVLDGHSVPLPEPLEVAHDLSKSPDMQGSHQLLVVSEEQFKVFTLPKVSAKLKLKLTA
LEGSRVRRVSVAHFGSRRAEDYGEHHLAVLTNLGDIQVVSLPLLKPQVRYSCIRREDVSGIASCVFTKYGQGFYLISPSEFERFSLSTKW
LVEPRCLVDSAETKNHRPGNGAGPKKAPSRARNSGTQSDGEEKQPGLVMERALLSDERVLKEIQSTLEGDRGSGNWRSHRAAVGCSLSNG

--------------------------------------------------------------

>40536_40536_25_ITGB4-LLGL2_ITGB4_chr17_73723586_ENST00000449880_LLGL2_chr17_73552126_ENST00000578363_length(amino acids)=419AA_BP=88
MAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRRCNTQAELLAAGCQRESIVVMESSFQITETV
EHGFPHQPSALGYSPSLRILAIGTRSGAIKLYGAPGVEFMGLHQENNAVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGASELQEDESF
TLRGPPGAAPSATQITVVLPHSSCELLYLGTESGNVFVVQLPAFRALEDRTISSDAVLQRLPEEARHRRVFEMVEALQEHPRDPNQILIG
YSRGLVVIWDLQGSRVLYHFLSSQQLENIWWQRDGRLLVSCHSDGSYCQWPVSSEAQQPEPLRSLVPYGPFPCKAITRILWLTTRQGLPF

--------------------------------------------------------------

>40536_40536_26_ITGB4-LLGL2_ITGB4_chr17_73723586_ENST00000449880_LLGL2_chr17_73552127_ENST00000167462_length(amino acids)=1078AA_BP=88
MAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRRCNTQAELLAAGCQRESIVVMESSFQITETV
EHGFPHQPSALGYSPSLRILAIGTRSGAIKLYGAPGVEFMGLHQENNAVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGASELQEDESF
TLRGPPGAAPSATQITVVLPHSSCELLYLGTESGNVFVVQLPAFRALEDRTISSDAVLQRLPEEARHRRVFEMVEALQEHPRDPNQILIG
YSRGLVVIWDLQGSRVLYHFLSSQQLENIWWQRDGRLLVSCHSDGSYCQWPVSSEAQQPEPLRSLVPYGPFPCKAITRILWLTTRQGLPF
TIFQGGMPRASYGDRHCISVIHDGQQTAFDFTSRVIGFTVLTEADPAATFDDPYALVVLAEEELVVIDLQTAGWPPVQLPYLASLHCSAI
TCSHHVSNIPLKLWERIIAAGSRQNAHFSTMEWPIDGGTSLTPAPPQRDLLLTGHEDGTVRFWDASGVCLRLLYKLSTVRVFLTDTDPNE
NFSAQGEDEWPPLRKVGSFDPYSDDPRLGIQKIFLCKYSGYLAVAGTAGQVLVLELNDEAAEQAVEQVEADLLQDQEGYRWKGHERLAAR
SGPVRFEPGFQPFVLVQCQPPAVVTSLALHSEWRLVAFGTSHGFGLFDHQQRRQVFVKCTLHPSDQLALEGPLSRVKSLKKSLRQSFRRM
RRSRVSSRKRHPAGPPGEAQEGSAKAERPGLQNMELAPVQRKIEARSAEDSFTGFVRTLYFADTYLKDSSRHCPSLWAGTNGGTIYAFSL
RVPPAERRMDEPVRAEQAKEIQLMHRAPVVGILVLDGHSVPLPEPLEVAHDLSKSPDMQGSHQLLVVSEEQFKVFTLPKVSAKLKLKLTA
LEGSRVRRVSVAHFGSRRAEDYGEHHLAVLTNLGDIQVVSLPLLKPQVRYSCIRREDVSGIASCVFTKYGQGFYLISPSEFERFSLSTKW

--------------------------------------------------------------

>40536_40536_27_ITGB4-LLGL2_ITGB4_chr17_73723586_ENST00000449880_LLGL2_chr17_73552127_ENST00000375227_length(amino acids)=419AA_BP=88
MAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRRCNTQAELLAAGCQRESIVVMESSFQITETV
EHGFPHQPSALGYSPSLRILAIGTRSGAIKLYGAPGVEFMGLHQENNAVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGASELQEDESF
TLRGPPGAAPSATQITVVLPHSSCELLYLGTESGNVFVVQLPAFRALEDRTISSDAVLQRLPEEARHRRVFEMVEALQEHPRDPNQILIG
YSRGLVVIWDLQGSRVLYHFLSSQQLENIWWQRDGRLLVSCHSDGSYCQWPVSSEAQQPEPLRSLVPYGPFPCKAITRILWLTTRQGLPF

--------------------------------------------------------------

>40536_40536_28_ITGB4-LLGL2_ITGB4_chr17_73723586_ENST00000449880_LLGL2_chr17_73552127_ENST00000392550_length(amino acids)=1083AA_BP=88
MAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRRCNTQAELLAAGCQRESIVVMESSFQITETV
EHGFPHQPSALGYSPSLRILAIGTRSGAIKLYGAPGVEFMGLHQENNAVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGASELQEDESF
TLRGPPGAAPSATQITVVLPHSSCELLYLGTESGNVFVVQLPAFRALEDRTISSDAVLQRLPEEARHRRVFEMVEALQEHPRDPNQILIG
YSRGLVVIWDLQGSRVLYHFLSSQQLENIWWQRDGRLLVSCHSDGSYCQWPVSSEAQQPEPLRSLVPYGPFPCKAITRILWLTTRQGLPF
TIFQGGMPRASYGDRHCISVIHDGQQTAFDFTSRVIGFTVLTEADPAATFDDPYALVVLAEEELVVIDLQTAGWPPVQLPYLASLHCSAI
TCSHHVSNIPLKLWERIIAAGSRQNAHFSTMEWPIDGGTSLTPAPPQRDLLLTGHEDGTVRFWDASGVCLRLLYKLSTVRVFLTDTDPNE
NFSAQGEDEWPPLRKVGSFDPYSDDPRLGIQKIFLCKYSGYLAVAGTAGQVLVLELNDEAAEQAVEQVEADLLQDQEGYRWKGHERLAAR
SGPVRFEPGFQPFVLVQCQPPAVVTSLALHSEWRLVAFGTSHGFGLFDHQQRRQVFVKCTLHPSDQLALEGPLSRVKSLKKSLRQSFRRM
RRSRVSSRKRHPAGPPGEAQEGSAKAERPGLQNMELAPVQRKIEARSAEDSFTGFVRTLYFADTYLKDSSRHCPSLWAGTNGGTIYAFSL
RVPPAERRMDEPVRAEQAKEIQLMHRAPVVGILVLDGHSVPLPEPLEVAHDLSKSPDMQGSHQLLVVSEEQFKVFTLPKVSAKLKLKLTA
LEGSRVRRVSVAHFGSRRAEDYGEHHLAVLTNLGDIQVVSLPLLKPQVRYSCIRREDVSGIASCVFTKYGQGFYLISPSEFERFSLSTKW
LVEPRCLVDSAETKNHRPGNGAGPKKAPSRARNSGTQSDGEEKQPGLVMERALLSDERVLKEIQSTLEGDRGSGNWRSHRAAVGCSLSNG

--------------------------------------------------------------

>40536_40536_29_ITGB4-LLGL2_ITGB4_chr17_73723586_ENST00000449880_LLGL2_chr17_73552127_ENST00000577200_length(amino acids)=1082AA_BP=88
MAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRRCNTQAELLAAGCQRESIVVMESSFQITETV
EHGFPHQPSALGYSPSLRILAIGTRSGAIKLYGAPGVEFMGLHQENNAVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGASELQEDESF
TLRGPPGAAPSATQITVVLPHSSCELLYLGTESGNVFVVQLPAFRALEDRTISSDAVLQRLPEEARHRRVFEMVEALQEHPRDPNQILIG
YSRGLVVIWDLQGSRVLYHFLSSQQLENIWWQRDGRLLVSCHSDGSYCQWPVSSEAQQPEPLRSLVPYGPFPCKAITRILWLTTRQGLPF
TIFQGGMPRASYGDRHCISVIHDGQQTAFDFTSRVIGFTVLTEADPAATFDDPYALVVLAEEELVVIDLQTAGWPPVQLPYLASLHCSAI
TCSHHVSNIPLKLWERIIAAGSRQNAHFSTMEWPIDGGTSLTPAPPQRDLLLTGHEDGTVRFWDASGVCLRLLYKLSTVRVFLTDTDPNE
NFSAQGEDEWPPLRKVGSFDPYSDDPRLGIQKIFLCKYSGYLAVAGTAGQVLVLELNDEAAEQAVEQVEADLLQDQEGYRWKGHERLAAR
SGPVRFEPGFQPFVLVQCQPPAVVTSLALHSEWRLVAFGTSHGFGLFDHQQRRQVFVKCTLHPSDQLALEGPLSRVKSLKKSLRQSFRRM
RRSRVSSRKRHPAGPPGEAQEGSAKAERPGLQNMELAPVQRKIEARSAEDSFTGFVRTLYFADTYLKDSSRHCPSLWAGTNGGTIYAFSL
RVPPAERRMDEPVRAEQAKEIQLMHRAPVVGILVLDGHSVPLPEPLEVAHDLSKSPDMQGSHQLLVVSEEQFKVFTLPKVSAKLKLKLTA
LEGSRVRRVSVAHFGSRRAEDYGEHHLAVLTNLGDIQVVSLPLLKPQVRYSCIRREDVSGIASCVFTKYGQGFYLISPSEFERFSLSTKW
LVEPRCLVDSAETKNHRPGNGAGPKKAPSRARNSGTQSDGEEKQPGLVMERALLSDERVLKEIQSTLEGDRGSGNWRSHRAAVGCSLSNG

--------------------------------------------------------------

>40536_40536_30_ITGB4-LLGL2_ITGB4_chr17_73723586_ENST00000449880_LLGL2_chr17_73552127_ENST00000578363_length(amino acids)=419AA_BP=88
MAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRRCNTQAELLAAGCQRESIVVMESSFQITETV
EHGFPHQPSALGYSPSLRILAIGTRSGAIKLYGAPGVEFMGLHQENNAVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGASELQEDESF
TLRGPPGAAPSATQITVVLPHSSCELLYLGTESGNVFVVQLPAFRALEDRTISSDAVLQRLPEEARHRRVFEMVEALQEHPRDPNQILIG
YSRGLVVIWDLQGSRVLYHFLSSQQLENIWWQRDGRLLVSCHSDGSYCQWPVSSEAQQPEPLRSLVPYGPFPCKAITRILWLTTRQGLPF

--------------------------------------------------------------

>40536_40536_31_ITGB4-LLGL2_ITGB4_chr17_73723586_ENST00000450894_LLGL2_chr17_73552126_ENST00000167462_length(amino acids)=1086AA_BP=96
MAGRGRKRMAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRRCNTQAELLAAGCQRESIVVMES
SFQITETVEHGFPHQPSALGYSPSLRILAIGTRSGAIKLYGAPGVEFMGLHQENNAVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGAS
ELQEDESFTLRGPPGAAPSATQITVVLPHSSCELLYLGTESGNVFVVQLPAFRALEDRTISSDAVLQRLPEEARHRRVFEMVEALQEHPR
DPNQILIGYSRGLVVIWDLQGSRVLYHFLSSQQLENIWWQRDGRLLVSCHSDGSYCQWPVSSEAQQPEPLRSLVPYGPFPCKAITRILWL
TTRQGLPFTIFQGGMPRASYGDRHCISVIHDGQQTAFDFTSRVIGFTVLTEADPAATFDDPYALVVLAEEELVVIDLQTAGWPPVQLPYL
ASLHCSAITCSHHVSNIPLKLWERIIAAGSRQNAHFSTMEWPIDGGTSLTPAPPQRDLLLTGHEDGTVRFWDASGVCLRLLYKLSTVRVF
LTDTDPNENFSAQGEDEWPPLRKVGSFDPYSDDPRLGIQKIFLCKYSGYLAVAGTAGQVLVLELNDEAAEQAVEQVEADLLQDQEGYRWK
GHERLAARSGPVRFEPGFQPFVLVQCQPPAVVTSLALHSEWRLVAFGTSHGFGLFDHQQRRQVFVKCTLHPSDQLALEGPLSRVKSLKKS
LRQSFRRMRRSRVSSRKRHPAGPPGEAQEGSAKAERPGLQNMELAPVQRKIEARSAEDSFTGFVRTLYFADTYLKDSSRHCPSLWAGTNG
GTIYAFSLRVPPAERRMDEPVRAEQAKEIQLMHRAPVVGILVLDGHSVPLPEPLEVAHDLSKSPDMQGSHQLLVVSEEQFKVFTLPKVSA
KLKLKLTALEGSRVRRVSVAHFGSRRAEDYGEHHLAVLTNLGDIQVVSLPLLKPQVRYSCIRREDVSGIASCVFTKYGQGFYLISPSEFE
RFSLSTKWLVEPRCLVDSAETKNHRPGNGAGPKKAPSRARNSGTQSDGEEKQPGLVMERALLSDERAATGVHIEPPWGAASAMAEQSEWL

--------------------------------------------------------------

>40536_40536_32_ITGB4-LLGL2_ITGB4_chr17_73723586_ENST00000450894_LLGL2_chr17_73552126_ENST00000375227_length(amino acids)=427AA_BP=96
MAGRGRKRMAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRRCNTQAELLAAGCQRESIVVMES
SFQITETVEHGFPHQPSALGYSPSLRILAIGTRSGAIKLYGAPGVEFMGLHQENNAVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGAS
ELQEDESFTLRGPPGAAPSATQITVVLPHSSCELLYLGTESGNVFVVQLPAFRALEDRTISSDAVLQRLPEEARHRRVFEMVEALQEHPR
DPNQILIGYSRGLVVIWDLQGSRVLYHFLSSQQLENIWWQRDGRLLVSCHSDGSYCQWPVSSEAQQPEPLRSLVPYGPFPCKAITRILWL

--------------------------------------------------------------

>40536_40536_33_ITGB4-LLGL2_ITGB4_chr17_73723586_ENST00000450894_LLGL2_chr17_73552126_ENST00000392550_length(amino acids)=1091AA_BP=96
MAGRGRKRMAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRRCNTQAELLAAGCQRESIVVMES
SFQITETVEHGFPHQPSALGYSPSLRILAIGTRSGAIKLYGAPGVEFMGLHQENNAVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGAS
ELQEDESFTLRGPPGAAPSATQITVVLPHSSCELLYLGTESGNVFVVQLPAFRALEDRTISSDAVLQRLPEEARHRRVFEMVEALQEHPR
DPNQILIGYSRGLVVIWDLQGSRVLYHFLSSQQLENIWWQRDGRLLVSCHSDGSYCQWPVSSEAQQPEPLRSLVPYGPFPCKAITRILWL
TTRQGLPFTIFQGGMPRASYGDRHCISVIHDGQQTAFDFTSRVIGFTVLTEADPAATFDDPYALVVLAEEELVVIDLQTAGWPPVQLPYL
ASLHCSAITCSHHVSNIPLKLWERIIAAGSRQNAHFSTMEWPIDGGTSLTPAPPQRDLLLTGHEDGTVRFWDASGVCLRLLYKLSTVRVF
LTDTDPNENFSAQGEDEWPPLRKVGSFDPYSDDPRLGIQKIFLCKYSGYLAVAGTAGQVLVLELNDEAAEQAVEQVEADLLQDQEGYRWK
GHERLAARSGPVRFEPGFQPFVLVQCQPPAVVTSLALHSEWRLVAFGTSHGFGLFDHQQRRQVFVKCTLHPSDQLALEGPLSRVKSLKKS
LRQSFRRMRRSRVSSRKRHPAGPPGEAQEGSAKAERPGLQNMELAPVQRKIEARSAEDSFTGFVRTLYFADTYLKDSSRHCPSLWAGTNG
GTIYAFSLRVPPAERRMDEPVRAEQAKEIQLMHRAPVVGILVLDGHSVPLPEPLEVAHDLSKSPDMQGSHQLLVVSEEQFKVFTLPKVSA
KLKLKLTALEGSRVRRVSVAHFGSRRAEDYGEHHLAVLTNLGDIQVVSLPLLKPQVRYSCIRREDVSGIASCVFTKYGQGFYLISPSEFE
RFSLSTKWLVEPRCLVDSAETKNHRPGNGAGPKKAPSRARNSGTQSDGEEKQPGLVMERALLSDERVLKEIQSTLEGDRGSGNWRSHRAA

--------------------------------------------------------------

>40536_40536_34_ITGB4-LLGL2_ITGB4_chr17_73723586_ENST00000450894_LLGL2_chr17_73552126_ENST00000577200_length(amino acids)=1090AA_BP=96
MAGRGRKRMAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRRCNTQAELLAAGCQRESIVVMES
SFQITETVEHGFPHQPSALGYSPSLRILAIGTRSGAIKLYGAPGVEFMGLHQENNAVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGAS
ELQEDESFTLRGPPGAAPSATQITVVLPHSSCELLYLGTESGNVFVVQLPAFRALEDRTISSDAVLQRLPEEARHRRVFEMVEALQEHPR
DPNQILIGYSRGLVVIWDLQGSRVLYHFLSSQQLENIWWQRDGRLLVSCHSDGSYCQWPVSSEAQQPEPLRSLVPYGPFPCKAITRILWL
TTRQGLPFTIFQGGMPRASYGDRHCISVIHDGQQTAFDFTSRVIGFTVLTEADPAATFDDPYALVVLAEEELVVIDLQTAGWPPVQLPYL
ASLHCSAITCSHHVSNIPLKLWERIIAAGSRQNAHFSTMEWPIDGGTSLTPAPPQRDLLLTGHEDGTVRFWDASGVCLRLLYKLSTVRVF
LTDTDPNENFSAQGEDEWPPLRKVGSFDPYSDDPRLGIQKIFLCKYSGYLAVAGTAGQVLVLELNDEAAEQAVEQVEADLLQDQEGYRWK
GHERLAARSGPVRFEPGFQPFVLVQCQPPAVVTSLALHSEWRLVAFGTSHGFGLFDHQQRRQVFVKCTLHPSDQLALEGPLSRVKSLKKS
LRQSFRRMRRSRVSSRKRHPAGPPGEAQEGSAKAERPGLQNMELAPVQRKIEARSAEDSFTGFVRTLYFADTYLKDSSRHCPSLWAGTNG
GTIYAFSLRVPPAERRMDEPVRAEQAKEIQLMHRAPVVGILVLDGHSVPLPEPLEVAHDLSKSPDMQGSHQLLVVSEEQFKVFTLPKVSA
KLKLKLTALEGSRVRRVSVAHFGSRRAEDYGEHHLAVLTNLGDIQVVSLPLLKPQVRYSCIRREDVSGIASCVFTKYGQGFYLISPSEFE
RFSLSTKWLVEPRCLVDSAETKNHRPGNGAGPKKAPSRARNSGTQSDGEEKQPGLVMERALLSDERVLKEIQSTLEGDRGSGNWRSHRAA

--------------------------------------------------------------

>40536_40536_35_ITGB4-LLGL2_ITGB4_chr17_73723586_ENST00000450894_LLGL2_chr17_73552126_ENST00000578363_length(amino acids)=427AA_BP=96
MAGRGRKRMAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRRCNTQAELLAAGCQRESIVVMES
SFQITETVEHGFPHQPSALGYSPSLRILAIGTRSGAIKLYGAPGVEFMGLHQENNAVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGAS
ELQEDESFTLRGPPGAAPSATQITVVLPHSSCELLYLGTESGNVFVVQLPAFRALEDRTISSDAVLQRLPEEARHRRVFEMVEALQEHPR
DPNQILIGYSRGLVVIWDLQGSRVLYHFLSSQQLENIWWQRDGRLLVSCHSDGSYCQWPVSSEAQQPEPLRSLVPYGPFPCKAITRILWL

--------------------------------------------------------------

>40536_40536_36_ITGB4-LLGL2_ITGB4_chr17_73723586_ENST00000450894_LLGL2_chr17_73552127_ENST00000167462_length(amino acids)=1086AA_BP=96
MAGRGRKRMAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRRCNTQAELLAAGCQRESIVVMES
SFQITETVEHGFPHQPSALGYSPSLRILAIGTRSGAIKLYGAPGVEFMGLHQENNAVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGAS
ELQEDESFTLRGPPGAAPSATQITVVLPHSSCELLYLGTESGNVFVVQLPAFRALEDRTISSDAVLQRLPEEARHRRVFEMVEALQEHPR
DPNQILIGYSRGLVVIWDLQGSRVLYHFLSSQQLENIWWQRDGRLLVSCHSDGSYCQWPVSSEAQQPEPLRSLVPYGPFPCKAITRILWL
TTRQGLPFTIFQGGMPRASYGDRHCISVIHDGQQTAFDFTSRVIGFTVLTEADPAATFDDPYALVVLAEEELVVIDLQTAGWPPVQLPYL
ASLHCSAITCSHHVSNIPLKLWERIIAAGSRQNAHFSTMEWPIDGGTSLTPAPPQRDLLLTGHEDGTVRFWDASGVCLRLLYKLSTVRVF
LTDTDPNENFSAQGEDEWPPLRKVGSFDPYSDDPRLGIQKIFLCKYSGYLAVAGTAGQVLVLELNDEAAEQAVEQVEADLLQDQEGYRWK
GHERLAARSGPVRFEPGFQPFVLVQCQPPAVVTSLALHSEWRLVAFGTSHGFGLFDHQQRRQVFVKCTLHPSDQLALEGPLSRVKSLKKS
LRQSFRRMRRSRVSSRKRHPAGPPGEAQEGSAKAERPGLQNMELAPVQRKIEARSAEDSFTGFVRTLYFADTYLKDSSRHCPSLWAGTNG
GTIYAFSLRVPPAERRMDEPVRAEQAKEIQLMHRAPVVGILVLDGHSVPLPEPLEVAHDLSKSPDMQGSHQLLVVSEEQFKVFTLPKVSA
KLKLKLTALEGSRVRRVSVAHFGSRRAEDYGEHHLAVLTNLGDIQVVSLPLLKPQVRYSCIRREDVSGIASCVFTKYGQGFYLISPSEFE
RFSLSTKWLVEPRCLVDSAETKNHRPGNGAGPKKAPSRARNSGTQSDGEEKQPGLVMERALLSDERAATGVHIEPPWGAASAMAEQSEWL

--------------------------------------------------------------

>40536_40536_37_ITGB4-LLGL2_ITGB4_chr17_73723586_ENST00000450894_LLGL2_chr17_73552127_ENST00000375227_length(amino acids)=427AA_BP=96
MAGRGRKRMAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRRCNTQAELLAAGCQRESIVVMES
SFQITETVEHGFPHQPSALGYSPSLRILAIGTRSGAIKLYGAPGVEFMGLHQENNAVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGAS
ELQEDESFTLRGPPGAAPSATQITVVLPHSSCELLYLGTESGNVFVVQLPAFRALEDRTISSDAVLQRLPEEARHRRVFEMVEALQEHPR
DPNQILIGYSRGLVVIWDLQGSRVLYHFLSSQQLENIWWQRDGRLLVSCHSDGSYCQWPVSSEAQQPEPLRSLVPYGPFPCKAITRILWL

--------------------------------------------------------------

>40536_40536_38_ITGB4-LLGL2_ITGB4_chr17_73723586_ENST00000450894_LLGL2_chr17_73552127_ENST00000392550_length(amino acids)=1091AA_BP=96
MAGRGRKRMAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRRCNTQAELLAAGCQRESIVVMES
SFQITETVEHGFPHQPSALGYSPSLRILAIGTRSGAIKLYGAPGVEFMGLHQENNAVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGAS
ELQEDESFTLRGPPGAAPSATQITVVLPHSSCELLYLGTESGNVFVVQLPAFRALEDRTISSDAVLQRLPEEARHRRVFEMVEALQEHPR
DPNQILIGYSRGLVVIWDLQGSRVLYHFLSSQQLENIWWQRDGRLLVSCHSDGSYCQWPVSSEAQQPEPLRSLVPYGPFPCKAITRILWL
TTRQGLPFTIFQGGMPRASYGDRHCISVIHDGQQTAFDFTSRVIGFTVLTEADPAATFDDPYALVVLAEEELVVIDLQTAGWPPVQLPYL
ASLHCSAITCSHHVSNIPLKLWERIIAAGSRQNAHFSTMEWPIDGGTSLTPAPPQRDLLLTGHEDGTVRFWDASGVCLRLLYKLSTVRVF
LTDTDPNENFSAQGEDEWPPLRKVGSFDPYSDDPRLGIQKIFLCKYSGYLAVAGTAGQVLVLELNDEAAEQAVEQVEADLLQDQEGYRWK
GHERLAARSGPVRFEPGFQPFVLVQCQPPAVVTSLALHSEWRLVAFGTSHGFGLFDHQQRRQVFVKCTLHPSDQLALEGPLSRVKSLKKS
LRQSFRRMRRSRVSSRKRHPAGPPGEAQEGSAKAERPGLQNMELAPVQRKIEARSAEDSFTGFVRTLYFADTYLKDSSRHCPSLWAGTNG
GTIYAFSLRVPPAERRMDEPVRAEQAKEIQLMHRAPVVGILVLDGHSVPLPEPLEVAHDLSKSPDMQGSHQLLVVSEEQFKVFTLPKVSA
KLKLKLTALEGSRVRRVSVAHFGSRRAEDYGEHHLAVLTNLGDIQVVSLPLLKPQVRYSCIRREDVSGIASCVFTKYGQGFYLISPSEFE
RFSLSTKWLVEPRCLVDSAETKNHRPGNGAGPKKAPSRARNSGTQSDGEEKQPGLVMERALLSDERVLKEIQSTLEGDRGSGNWRSHRAA

--------------------------------------------------------------

>40536_40536_39_ITGB4-LLGL2_ITGB4_chr17_73723586_ENST00000450894_LLGL2_chr17_73552127_ENST00000577200_length(amino acids)=1090AA_BP=96
MAGRGRKRMAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRRCNTQAELLAAGCQRESIVVMES
SFQITETVEHGFPHQPSALGYSPSLRILAIGTRSGAIKLYGAPGVEFMGLHQENNAVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGAS
ELQEDESFTLRGPPGAAPSATQITVVLPHSSCELLYLGTESGNVFVVQLPAFRALEDRTISSDAVLQRLPEEARHRRVFEMVEALQEHPR
DPNQILIGYSRGLVVIWDLQGSRVLYHFLSSQQLENIWWQRDGRLLVSCHSDGSYCQWPVSSEAQQPEPLRSLVPYGPFPCKAITRILWL
TTRQGLPFTIFQGGMPRASYGDRHCISVIHDGQQTAFDFTSRVIGFTVLTEADPAATFDDPYALVVLAEEELVVIDLQTAGWPPVQLPYL
ASLHCSAITCSHHVSNIPLKLWERIIAAGSRQNAHFSTMEWPIDGGTSLTPAPPQRDLLLTGHEDGTVRFWDASGVCLRLLYKLSTVRVF
LTDTDPNENFSAQGEDEWPPLRKVGSFDPYSDDPRLGIQKIFLCKYSGYLAVAGTAGQVLVLELNDEAAEQAVEQVEADLLQDQEGYRWK
GHERLAARSGPVRFEPGFQPFVLVQCQPPAVVTSLALHSEWRLVAFGTSHGFGLFDHQQRRQVFVKCTLHPSDQLALEGPLSRVKSLKKS
LRQSFRRMRRSRVSSRKRHPAGPPGEAQEGSAKAERPGLQNMELAPVQRKIEARSAEDSFTGFVRTLYFADTYLKDSSRHCPSLWAGTNG
GTIYAFSLRVPPAERRMDEPVRAEQAKEIQLMHRAPVVGILVLDGHSVPLPEPLEVAHDLSKSPDMQGSHQLLVVSEEQFKVFTLPKVSA
KLKLKLTALEGSRVRRVSVAHFGSRRAEDYGEHHLAVLTNLGDIQVVSLPLLKPQVRYSCIRREDVSGIASCVFTKYGQGFYLISPSEFE
RFSLSTKWLVEPRCLVDSAETKNHRPGNGAGPKKAPSRARNSGTQSDGEEKQPGLVMERALLSDERVLKEIQSTLEGDRGSGNWRSHRAA

--------------------------------------------------------------

>40536_40536_40_ITGB4-LLGL2_ITGB4_chr17_73723586_ENST00000450894_LLGL2_chr17_73552127_ENST00000578363_length(amino acids)=427AA_BP=96
MAGRGRKRMAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRRCNTQAELLAAGCQRESIVVMES
SFQITETVEHGFPHQPSALGYSPSLRILAIGTRSGAIKLYGAPGVEFMGLHQENNAVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGAS
ELQEDESFTLRGPPGAAPSATQITVVLPHSSCELLYLGTESGNVFVVQLPAFRALEDRTISSDAVLQRLPEEARHRRVFEMVEALQEHPR
DPNQILIGYSRGLVVIWDLQGSRVLYHFLSSQQLENIWWQRDGRLLVSCHSDGSYCQWPVSSEAQQPEPLRSLVPYGPFPCKAITRILWL

--------------------------------------------------------------

>40536_40536_41_ITGB4-LLGL2_ITGB4_chr17_73723586_ENST00000579662_LLGL2_chr17_73552126_ENST00000167462_length(amino acids)=1078AA_BP=88
MAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRRCNTQAELLAAGCQRESIVVMESSFQITETV
EHGFPHQPSALGYSPSLRILAIGTRSGAIKLYGAPGVEFMGLHQENNAVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGASELQEDESF
TLRGPPGAAPSATQITVVLPHSSCELLYLGTESGNVFVVQLPAFRALEDRTISSDAVLQRLPEEARHRRVFEMVEALQEHPRDPNQILIG
YSRGLVVIWDLQGSRVLYHFLSSQQLENIWWQRDGRLLVSCHSDGSYCQWPVSSEAQQPEPLRSLVPYGPFPCKAITRILWLTTRQGLPF
TIFQGGMPRASYGDRHCISVIHDGQQTAFDFTSRVIGFTVLTEADPAATFDDPYALVVLAEEELVVIDLQTAGWPPVQLPYLASLHCSAI
TCSHHVSNIPLKLWERIIAAGSRQNAHFSTMEWPIDGGTSLTPAPPQRDLLLTGHEDGTVRFWDASGVCLRLLYKLSTVRVFLTDTDPNE
NFSAQGEDEWPPLRKVGSFDPYSDDPRLGIQKIFLCKYSGYLAVAGTAGQVLVLELNDEAAEQAVEQVEADLLQDQEGYRWKGHERLAAR
SGPVRFEPGFQPFVLVQCQPPAVVTSLALHSEWRLVAFGTSHGFGLFDHQQRRQVFVKCTLHPSDQLALEGPLSRVKSLKKSLRQSFRRM
RRSRVSSRKRHPAGPPGEAQEGSAKAERPGLQNMELAPVQRKIEARSAEDSFTGFVRTLYFADTYLKDSSRHCPSLWAGTNGGTIYAFSL
RVPPAERRMDEPVRAEQAKEIQLMHRAPVVGILVLDGHSVPLPEPLEVAHDLSKSPDMQGSHQLLVVSEEQFKVFTLPKVSAKLKLKLTA
LEGSRVRRVSVAHFGSRRAEDYGEHHLAVLTNLGDIQVVSLPLLKPQVRYSCIRREDVSGIASCVFTKYGQGFYLISPSEFERFSLSTKW

--------------------------------------------------------------

>40536_40536_42_ITGB4-LLGL2_ITGB4_chr17_73723586_ENST00000579662_LLGL2_chr17_73552126_ENST00000375227_length(amino acids)=419AA_BP=88
MAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRRCNTQAELLAAGCQRESIVVMESSFQITETV
EHGFPHQPSALGYSPSLRILAIGTRSGAIKLYGAPGVEFMGLHQENNAVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGASELQEDESF
TLRGPPGAAPSATQITVVLPHSSCELLYLGTESGNVFVVQLPAFRALEDRTISSDAVLQRLPEEARHRRVFEMVEALQEHPRDPNQILIG
YSRGLVVIWDLQGSRVLYHFLSSQQLENIWWQRDGRLLVSCHSDGSYCQWPVSSEAQQPEPLRSLVPYGPFPCKAITRILWLTTRQGLPF

--------------------------------------------------------------

>40536_40536_43_ITGB4-LLGL2_ITGB4_chr17_73723586_ENST00000579662_LLGL2_chr17_73552126_ENST00000392550_length(amino acids)=1083AA_BP=88
MAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRRCNTQAELLAAGCQRESIVVMESSFQITETV
EHGFPHQPSALGYSPSLRILAIGTRSGAIKLYGAPGVEFMGLHQENNAVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGASELQEDESF
TLRGPPGAAPSATQITVVLPHSSCELLYLGTESGNVFVVQLPAFRALEDRTISSDAVLQRLPEEARHRRVFEMVEALQEHPRDPNQILIG
YSRGLVVIWDLQGSRVLYHFLSSQQLENIWWQRDGRLLVSCHSDGSYCQWPVSSEAQQPEPLRSLVPYGPFPCKAITRILWLTTRQGLPF
TIFQGGMPRASYGDRHCISVIHDGQQTAFDFTSRVIGFTVLTEADPAATFDDPYALVVLAEEELVVIDLQTAGWPPVQLPYLASLHCSAI
TCSHHVSNIPLKLWERIIAAGSRQNAHFSTMEWPIDGGTSLTPAPPQRDLLLTGHEDGTVRFWDASGVCLRLLYKLSTVRVFLTDTDPNE
NFSAQGEDEWPPLRKVGSFDPYSDDPRLGIQKIFLCKYSGYLAVAGTAGQVLVLELNDEAAEQAVEQVEADLLQDQEGYRWKGHERLAAR
SGPVRFEPGFQPFVLVQCQPPAVVTSLALHSEWRLVAFGTSHGFGLFDHQQRRQVFVKCTLHPSDQLALEGPLSRVKSLKKSLRQSFRRM
RRSRVSSRKRHPAGPPGEAQEGSAKAERPGLQNMELAPVQRKIEARSAEDSFTGFVRTLYFADTYLKDSSRHCPSLWAGTNGGTIYAFSL
RVPPAERRMDEPVRAEQAKEIQLMHRAPVVGILVLDGHSVPLPEPLEVAHDLSKSPDMQGSHQLLVVSEEQFKVFTLPKVSAKLKLKLTA
LEGSRVRRVSVAHFGSRRAEDYGEHHLAVLTNLGDIQVVSLPLLKPQVRYSCIRREDVSGIASCVFTKYGQGFYLISPSEFERFSLSTKW
LVEPRCLVDSAETKNHRPGNGAGPKKAPSRARNSGTQSDGEEKQPGLVMERALLSDERVLKEIQSTLEGDRGSGNWRSHRAAVGCSLSNG

--------------------------------------------------------------

>40536_40536_44_ITGB4-LLGL2_ITGB4_chr17_73723586_ENST00000579662_LLGL2_chr17_73552126_ENST00000577200_length(amino acids)=1082AA_BP=88
MAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRRCNTQAELLAAGCQRESIVVMESSFQITETV
EHGFPHQPSALGYSPSLRILAIGTRSGAIKLYGAPGVEFMGLHQENNAVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGASELQEDESF
TLRGPPGAAPSATQITVVLPHSSCELLYLGTESGNVFVVQLPAFRALEDRTISSDAVLQRLPEEARHRRVFEMVEALQEHPRDPNQILIG
YSRGLVVIWDLQGSRVLYHFLSSQQLENIWWQRDGRLLVSCHSDGSYCQWPVSSEAQQPEPLRSLVPYGPFPCKAITRILWLTTRQGLPF
TIFQGGMPRASYGDRHCISVIHDGQQTAFDFTSRVIGFTVLTEADPAATFDDPYALVVLAEEELVVIDLQTAGWPPVQLPYLASLHCSAI
TCSHHVSNIPLKLWERIIAAGSRQNAHFSTMEWPIDGGTSLTPAPPQRDLLLTGHEDGTVRFWDASGVCLRLLYKLSTVRVFLTDTDPNE
NFSAQGEDEWPPLRKVGSFDPYSDDPRLGIQKIFLCKYSGYLAVAGTAGQVLVLELNDEAAEQAVEQVEADLLQDQEGYRWKGHERLAAR
SGPVRFEPGFQPFVLVQCQPPAVVTSLALHSEWRLVAFGTSHGFGLFDHQQRRQVFVKCTLHPSDQLALEGPLSRVKSLKKSLRQSFRRM
RRSRVSSRKRHPAGPPGEAQEGSAKAERPGLQNMELAPVQRKIEARSAEDSFTGFVRTLYFADTYLKDSSRHCPSLWAGTNGGTIYAFSL
RVPPAERRMDEPVRAEQAKEIQLMHRAPVVGILVLDGHSVPLPEPLEVAHDLSKSPDMQGSHQLLVVSEEQFKVFTLPKVSAKLKLKLTA
LEGSRVRRVSVAHFGSRRAEDYGEHHLAVLTNLGDIQVVSLPLLKPQVRYSCIRREDVSGIASCVFTKYGQGFYLISPSEFERFSLSTKW
LVEPRCLVDSAETKNHRPGNGAGPKKAPSRARNSGTQSDGEEKQPGLVMERALLSDERVLKEIQSTLEGDRGSGNWRSHRAAVGCSLSNG

--------------------------------------------------------------

>40536_40536_45_ITGB4-LLGL2_ITGB4_chr17_73723586_ENST00000579662_LLGL2_chr17_73552126_ENST00000578363_length(amino acids)=419AA_BP=88
MAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRRCNTQAELLAAGCQRESIVVMESSFQITETV
EHGFPHQPSALGYSPSLRILAIGTRSGAIKLYGAPGVEFMGLHQENNAVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGASELQEDESF
TLRGPPGAAPSATQITVVLPHSSCELLYLGTESGNVFVVQLPAFRALEDRTISSDAVLQRLPEEARHRRVFEMVEALQEHPRDPNQILIG
YSRGLVVIWDLQGSRVLYHFLSSQQLENIWWQRDGRLLVSCHSDGSYCQWPVSSEAQQPEPLRSLVPYGPFPCKAITRILWLTTRQGLPF

--------------------------------------------------------------

>40536_40536_46_ITGB4-LLGL2_ITGB4_chr17_73723586_ENST00000579662_LLGL2_chr17_73552127_ENST00000167462_length(amino acids)=1078AA_BP=88
MAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRRCNTQAELLAAGCQRESIVVMESSFQITETV
EHGFPHQPSALGYSPSLRILAIGTRSGAIKLYGAPGVEFMGLHQENNAVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGASELQEDESF
TLRGPPGAAPSATQITVVLPHSSCELLYLGTESGNVFVVQLPAFRALEDRTISSDAVLQRLPEEARHRRVFEMVEALQEHPRDPNQILIG
YSRGLVVIWDLQGSRVLYHFLSSQQLENIWWQRDGRLLVSCHSDGSYCQWPVSSEAQQPEPLRSLVPYGPFPCKAITRILWLTTRQGLPF
TIFQGGMPRASYGDRHCISVIHDGQQTAFDFTSRVIGFTVLTEADPAATFDDPYALVVLAEEELVVIDLQTAGWPPVQLPYLASLHCSAI
TCSHHVSNIPLKLWERIIAAGSRQNAHFSTMEWPIDGGTSLTPAPPQRDLLLTGHEDGTVRFWDASGVCLRLLYKLSTVRVFLTDTDPNE
NFSAQGEDEWPPLRKVGSFDPYSDDPRLGIQKIFLCKYSGYLAVAGTAGQVLVLELNDEAAEQAVEQVEADLLQDQEGYRWKGHERLAAR
SGPVRFEPGFQPFVLVQCQPPAVVTSLALHSEWRLVAFGTSHGFGLFDHQQRRQVFVKCTLHPSDQLALEGPLSRVKSLKKSLRQSFRRM
RRSRVSSRKRHPAGPPGEAQEGSAKAERPGLQNMELAPVQRKIEARSAEDSFTGFVRTLYFADTYLKDSSRHCPSLWAGTNGGTIYAFSL
RVPPAERRMDEPVRAEQAKEIQLMHRAPVVGILVLDGHSVPLPEPLEVAHDLSKSPDMQGSHQLLVVSEEQFKVFTLPKVSAKLKLKLTA
LEGSRVRRVSVAHFGSRRAEDYGEHHLAVLTNLGDIQVVSLPLLKPQVRYSCIRREDVSGIASCVFTKYGQGFYLISPSEFERFSLSTKW

--------------------------------------------------------------

>40536_40536_47_ITGB4-LLGL2_ITGB4_chr17_73723586_ENST00000579662_LLGL2_chr17_73552127_ENST00000375227_length(amino acids)=419AA_BP=88
MAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRRCNTQAELLAAGCQRESIVVMESSFQITETV
EHGFPHQPSALGYSPSLRILAIGTRSGAIKLYGAPGVEFMGLHQENNAVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGASELQEDESF
TLRGPPGAAPSATQITVVLPHSSCELLYLGTESGNVFVVQLPAFRALEDRTISSDAVLQRLPEEARHRRVFEMVEALQEHPRDPNQILIG
YSRGLVVIWDLQGSRVLYHFLSSQQLENIWWQRDGRLLVSCHSDGSYCQWPVSSEAQQPEPLRSLVPYGPFPCKAITRILWLTTRQGLPF

--------------------------------------------------------------

>40536_40536_48_ITGB4-LLGL2_ITGB4_chr17_73723586_ENST00000579662_LLGL2_chr17_73552127_ENST00000392550_length(amino acids)=1083AA_BP=88
MAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRRCNTQAELLAAGCQRESIVVMESSFQITETV
EHGFPHQPSALGYSPSLRILAIGTRSGAIKLYGAPGVEFMGLHQENNAVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGASELQEDESF
TLRGPPGAAPSATQITVVLPHSSCELLYLGTESGNVFVVQLPAFRALEDRTISSDAVLQRLPEEARHRRVFEMVEALQEHPRDPNQILIG
YSRGLVVIWDLQGSRVLYHFLSSQQLENIWWQRDGRLLVSCHSDGSYCQWPVSSEAQQPEPLRSLVPYGPFPCKAITRILWLTTRQGLPF
TIFQGGMPRASYGDRHCISVIHDGQQTAFDFTSRVIGFTVLTEADPAATFDDPYALVVLAEEELVVIDLQTAGWPPVQLPYLASLHCSAI
TCSHHVSNIPLKLWERIIAAGSRQNAHFSTMEWPIDGGTSLTPAPPQRDLLLTGHEDGTVRFWDASGVCLRLLYKLSTVRVFLTDTDPNE
NFSAQGEDEWPPLRKVGSFDPYSDDPRLGIQKIFLCKYSGYLAVAGTAGQVLVLELNDEAAEQAVEQVEADLLQDQEGYRWKGHERLAAR
SGPVRFEPGFQPFVLVQCQPPAVVTSLALHSEWRLVAFGTSHGFGLFDHQQRRQVFVKCTLHPSDQLALEGPLSRVKSLKKSLRQSFRRM
RRSRVSSRKRHPAGPPGEAQEGSAKAERPGLQNMELAPVQRKIEARSAEDSFTGFVRTLYFADTYLKDSSRHCPSLWAGTNGGTIYAFSL
RVPPAERRMDEPVRAEQAKEIQLMHRAPVVGILVLDGHSVPLPEPLEVAHDLSKSPDMQGSHQLLVVSEEQFKVFTLPKVSAKLKLKLTA
LEGSRVRRVSVAHFGSRRAEDYGEHHLAVLTNLGDIQVVSLPLLKPQVRYSCIRREDVSGIASCVFTKYGQGFYLISPSEFERFSLSTKW
LVEPRCLVDSAETKNHRPGNGAGPKKAPSRARNSGTQSDGEEKQPGLVMERALLSDERVLKEIQSTLEGDRGSGNWRSHRAAVGCSLSNG

--------------------------------------------------------------

>40536_40536_49_ITGB4-LLGL2_ITGB4_chr17_73723586_ENST00000579662_LLGL2_chr17_73552127_ENST00000577200_length(amino acids)=1082AA_BP=88
MAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRRCNTQAELLAAGCQRESIVVMESSFQITETV
EHGFPHQPSALGYSPSLRILAIGTRSGAIKLYGAPGVEFMGLHQENNAVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGASELQEDESF
TLRGPPGAAPSATQITVVLPHSSCELLYLGTESGNVFVVQLPAFRALEDRTISSDAVLQRLPEEARHRRVFEMVEALQEHPRDPNQILIG
YSRGLVVIWDLQGSRVLYHFLSSQQLENIWWQRDGRLLVSCHSDGSYCQWPVSSEAQQPEPLRSLVPYGPFPCKAITRILWLTTRQGLPF
TIFQGGMPRASYGDRHCISVIHDGQQTAFDFTSRVIGFTVLTEADPAATFDDPYALVVLAEEELVVIDLQTAGWPPVQLPYLASLHCSAI
TCSHHVSNIPLKLWERIIAAGSRQNAHFSTMEWPIDGGTSLTPAPPQRDLLLTGHEDGTVRFWDASGVCLRLLYKLSTVRVFLTDTDPNE
NFSAQGEDEWPPLRKVGSFDPYSDDPRLGIQKIFLCKYSGYLAVAGTAGQVLVLELNDEAAEQAVEQVEADLLQDQEGYRWKGHERLAAR
SGPVRFEPGFQPFVLVQCQPPAVVTSLALHSEWRLVAFGTSHGFGLFDHQQRRQVFVKCTLHPSDQLALEGPLSRVKSLKKSLRQSFRRM
RRSRVSSRKRHPAGPPGEAQEGSAKAERPGLQNMELAPVQRKIEARSAEDSFTGFVRTLYFADTYLKDSSRHCPSLWAGTNGGTIYAFSL
RVPPAERRMDEPVRAEQAKEIQLMHRAPVVGILVLDGHSVPLPEPLEVAHDLSKSPDMQGSHQLLVVSEEQFKVFTLPKVSAKLKLKLTA
LEGSRVRRVSVAHFGSRRAEDYGEHHLAVLTNLGDIQVVSLPLLKPQVRYSCIRREDVSGIASCVFTKYGQGFYLISPSEFERFSLSTKW
LVEPRCLVDSAETKNHRPGNGAGPKKAPSRARNSGTQSDGEEKQPGLVMERALLSDERVLKEIQSTLEGDRGSGNWRSHRAAVGCSLSNG

--------------------------------------------------------------

>40536_40536_50_ITGB4-LLGL2_ITGB4_chr17_73723586_ENST00000579662_LLGL2_chr17_73552127_ENST00000578363_length(amino acids)=419AA_BP=88
MAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRRCNTQAELLAAGCQRESIVVMESSFQITETV
EHGFPHQPSALGYSPSLRILAIGTRSGAIKLYGAPGVEFMGLHQENNAVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGASELQEDESF
TLRGPPGAAPSATQITVVLPHSSCELLYLGTESGNVFVVQLPAFRALEDRTISSDAVLQRLPEEARHRRVFEMVEALQEHPRDPNQILIG
YSRGLVVIWDLQGSRVLYHFLSSQQLENIWWQRDGRLLVSCHSDGSYCQWPVSSEAQQPEPLRSLVPYGPFPCKAITRILWLTTRQGLPF

--------------------------------------------------------------

Top

Fusion Protein Functional Features


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr17:73529786/chr17:73748255)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ITGB4

P16144

LLGL2

Q6P1M3

FUNCTION: Integrin alpha-6/beta-4 is a receptor for laminin. Plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity and motility. ITGA6:ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling (PubMed:20682778). ITGA6:ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling (PubMed:22351760). ITGA6:ITGB4 binds to IGF2 and this binding is essential for IGF2 signaling (PubMed:28873464). {ECO:0000269|PubMed:12482924, ECO:0000269|PubMed:19403692, ECO:0000269|PubMed:20682778, ECO:0000269|PubMed:22351760, ECO:0000269|PubMed:28873464}.FUNCTION: Part of a complex with GPSM2/LGN, PRKCI/aPKC and PARD6B/Par-6, which may ensure the correct organization and orientation of bipolar spindles for normal cell division. This complex plays roles in the initial phase of the establishment of epithelial cell polarity. {ECO:0000269|PubMed:15632202}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

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* Minus value of BPloci means that the break pointn is located before the CDS.
- Retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneITGB4chr17:73723586chr17:73552126ENST00000200181+44029_7388.01823.0DomainNote=PSI
HgeneITGB4chr17:73723586chr17:73552126ENST00000339591+44029_7388.01806.0DomainNote=PSI
HgeneITGB4chr17:73723586chr17:73552126ENST00000449880+33929_7388.01806.0DomainNote=PSI
HgeneITGB4chr17:73723586chr17:73552126ENST00000450894+43929_7388.01753.0DomainNote=PSI
HgeneITGB4chr17:73723586chr17:73552126ENST00000579662+43929_7388.01753.0DomainNote=PSI
HgeneITGB4chr17:73723586chr17:73552127ENST00000200181+44029_7388.01823.0DomainNote=PSI
HgeneITGB4chr17:73723586chr17:73552127ENST00000339591+44029_7388.01806.0DomainNote=PSI
HgeneITGB4chr17:73723586chr17:73552127ENST00000449880+33929_7388.01806.0DomainNote=PSI
HgeneITGB4chr17:73723586chr17:73552127ENST00000450894+43929_7388.01753.0DomainNote=PSI
HgeneITGB4chr17:73723586chr17:73552127ENST00000579662+43929_7388.01753.0DomainNote=PSI
TgeneLLGL2chr17:73723586chr17:73552126ENST00000167462125132_16925.01016.0RepeatNote=WD 3
TgeneLLGL2chr17:73723586chr17:73552126ENST00000167462125193_22725.01016.0RepeatNote=WD 4
TgeneLLGL2chr17:73723586chr17:73552126ENST00000167462125233_26825.01016.0RepeatNote=WD 5
TgeneLLGL2chr17:73723586chr17:73552126ENST00000167462125282_32425.01016.0RepeatNote=WD 6
TgeneLLGL2chr17:73723586chr17:73552126ENST00000167462125332_36625.01016.0RepeatNote=WD 7
TgeneLLGL2chr17:73723586chr17:73552126ENST0000016746212536_6925.01016.0RepeatNote=WD 1
TgeneLLGL2chr17:73723586chr17:73552126ENST00000167462125388_46425.01016.0RepeatNote=WD 8
TgeneLLGL2chr17:73723586chr17:73552126ENST00000167462125508_58325.01016.0RepeatNote=WD 9
TgeneLLGL2chr17:73723586chr17:73552126ENST00000167462125592_65325.01016.0RepeatNote=WD 10
TgeneLLGL2chr17:73723586chr17:73552126ENST00000167462125713_76925.01016.0RepeatNote=WD 11
TgeneLLGL2chr17:73723586chr17:73552126ENST0000016746212576_11725.01016.0RepeatNote=WD 2
TgeneLLGL2chr17:73723586chr17:73552126ENST00000167462125778_83025.01016.0RepeatNote=WD 12
TgeneLLGL2chr17:73723586chr17:73552126ENST00000167462125835_88825.01016.0RepeatNote=WD 13
TgeneLLGL2chr17:73723586chr17:73552126ENST00000167462125902_92525.01016.0RepeatNote=WD 14
TgeneLLGL2chr17:73723586chr17:73552126ENST00000375227110132_16925.0357.0RepeatNote=WD 3
TgeneLLGL2chr17:73723586chr17:73552126ENST00000375227110193_22725.0357.0RepeatNote=WD 4
TgeneLLGL2chr17:73723586chr17:73552126ENST00000375227110233_26825.0357.0RepeatNote=WD 5
TgeneLLGL2chr17:73723586chr17:73552126ENST00000375227110282_32425.0357.0RepeatNote=WD 6
TgeneLLGL2chr17:73723586chr17:73552126ENST00000375227110332_36625.0357.0RepeatNote=WD 7
TgeneLLGL2chr17:73723586chr17:73552126ENST0000037522711036_6925.0357.0RepeatNote=WD 1
TgeneLLGL2chr17:73723586chr17:73552126ENST00000375227110388_46425.0357.0RepeatNote=WD 8
TgeneLLGL2chr17:73723586chr17:73552126ENST00000375227110508_58325.0357.0RepeatNote=WD 9
TgeneLLGL2chr17:73723586chr17:73552126ENST00000375227110592_65325.0357.0RepeatNote=WD 10
TgeneLLGL2chr17:73723586chr17:73552126ENST00000375227110713_76925.0357.0RepeatNote=WD 11
TgeneLLGL2chr17:73723586chr17:73552126ENST0000037522711076_11725.0357.0RepeatNote=WD 2
TgeneLLGL2chr17:73723586chr17:73552126ENST00000375227110778_83025.0357.0RepeatNote=WD 12
TgeneLLGL2chr17:73723586chr17:73552126ENST00000375227110835_88825.0357.0RepeatNote=WD 13
TgeneLLGL2chr17:73723586chr17:73552126ENST00000375227110902_92525.0357.0RepeatNote=WD 14
TgeneLLGL2chr17:73723586chr17:73552126ENST00000392550126132_16925.01021.0RepeatNote=WD 3
TgeneLLGL2chr17:73723586chr17:73552126ENST00000392550126193_22725.01021.0RepeatNote=WD 4
TgeneLLGL2chr17:73723586chr17:73552126ENST00000392550126233_26825.01021.0RepeatNote=WD 5
TgeneLLGL2chr17:73723586chr17:73552126ENST00000392550126282_32425.01021.0RepeatNote=WD 6
TgeneLLGL2chr17:73723586chr17:73552126ENST00000392550126332_36625.01021.0RepeatNote=WD 7
TgeneLLGL2chr17:73723586chr17:73552126ENST0000039255012636_6925.01021.0RepeatNote=WD 1
TgeneLLGL2chr17:73723586chr17:73552126ENST00000392550126388_46425.01021.0RepeatNote=WD 8
TgeneLLGL2chr17:73723586chr17:73552126ENST00000392550126508_58325.01021.0RepeatNote=WD 9
TgeneLLGL2chr17:73723586chr17:73552126ENST00000392550126592_65325.01021.0RepeatNote=WD 10
TgeneLLGL2chr17:73723586chr17:73552126ENST00000392550126713_76925.01021.0RepeatNote=WD 11
TgeneLLGL2chr17:73723586chr17:73552126ENST0000039255012676_11725.01021.0RepeatNote=WD 2
TgeneLLGL2chr17:73723586chr17:73552126ENST00000392550126778_83025.01021.0RepeatNote=WD 12
TgeneLLGL2chr17:73723586chr17:73552126ENST00000392550126835_88825.01021.0RepeatNote=WD 13
TgeneLLGL2chr17:73723586chr17:73552126ENST00000392550126902_92525.01021.0RepeatNote=WD 14
TgeneLLGL2chr17:73723586chr17:73552126ENST00000578363211132_16925.0357.0RepeatNote=WD 3
TgeneLLGL2chr17:73723586chr17:73552126ENST00000578363211193_22725.0357.0RepeatNote=WD 4
TgeneLLGL2chr17:73723586chr17:73552126ENST00000578363211233_26825.0357.0RepeatNote=WD 5
TgeneLLGL2chr17:73723586chr17:73552126ENST00000578363211282_32425.0357.0RepeatNote=WD 6
TgeneLLGL2chr17:73723586chr17:73552126ENST00000578363211332_36625.0357.0RepeatNote=WD 7
TgeneLLGL2chr17:73723586chr17:73552126ENST0000057836321136_6925.0357.0RepeatNote=WD 1
TgeneLLGL2chr17:73723586chr17:73552126ENST00000578363211388_46425.0357.0RepeatNote=WD 8
TgeneLLGL2chr17:73723586chr17:73552126ENST00000578363211508_58325.0357.0RepeatNote=WD 9
TgeneLLGL2chr17:73723586chr17:73552126ENST00000578363211592_65325.0357.0RepeatNote=WD 10
TgeneLLGL2chr17:73723586chr17:73552126ENST00000578363211713_76925.0357.0RepeatNote=WD 11
TgeneLLGL2chr17:73723586chr17:73552126ENST0000057836321176_11725.0357.0RepeatNote=WD 2
TgeneLLGL2chr17:73723586chr17:73552126ENST00000578363211778_83025.0357.0RepeatNote=WD 12
TgeneLLGL2chr17:73723586chr17:73552126ENST00000578363211835_88825.0357.0RepeatNote=WD 13
TgeneLLGL2chr17:73723586chr17:73552126ENST00000578363211902_92525.0357.0RepeatNote=WD 14
TgeneLLGL2chr17:73723586chr17:73552127ENST00000167462125132_16925.01016.0RepeatNote=WD 3
TgeneLLGL2chr17:73723586chr17:73552127ENST00000167462125193_22725.01016.0RepeatNote=WD 4
TgeneLLGL2chr17:73723586chr17:73552127ENST00000167462125233_26825.01016.0RepeatNote=WD 5
TgeneLLGL2chr17:73723586chr17:73552127ENST00000167462125282_32425.01016.0RepeatNote=WD 6
TgeneLLGL2chr17:73723586chr17:73552127ENST00000167462125332_36625.01016.0RepeatNote=WD 7
TgeneLLGL2chr17:73723586chr17:73552127ENST0000016746212536_6925.01016.0RepeatNote=WD 1
TgeneLLGL2chr17:73723586chr17:73552127ENST00000167462125388_46425.01016.0RepeatNote=WD 8
TgeneLLGL2chr17:73723586chr17:73552127ENST00000167462125508_58325.01016.0RepeatNote=WD 9
TgeneLLGL2chr17:73723586chr17:73552127ENST00000167462125592_65325.01016.0RepeatNote=WD 10
TgeneLLGL2chr17:73723586chr17:73552127ENST00000167462125713_76925.01016.0RepeatNote=WD 11
TgeneLLGL2chr17:73723586chr17:73552127ENST0000016746212576_11725.01016.0RepeatNote=WD 2
TgeneLLGL2chr17:73723586chr17:73552127ENST00000167462125778_83025.01016.0RepeatNote=WD 12
TgeneLLGL2chr17:73723586chr17:73552127ENST00000167462125835_88825.01016.0RepeatNote=WD 13
TgeneLLGL2chr17:73723586chr17:73552127ENST00000167462125902_92525.01016.0RepeatNote=WD 14
TgeneLLGL2chr17:73723586chr17:73552127ENST00000375227110132_16925.0357.0RepeatNote=WD 3
TgeneLLGL2chr17:73723586chr17:73552127ENST00000375227110193_22725.0357.0RepeatNote=WD 4
TgeneLLGL2chr17:73723586chr17:73552127ENST00000375227110233_26825.0357.0RepeatNote=WD 5
TgeneLLGL2chr17:73723586chr17:73552127ENST00000375227110282_32425.0357.0RepeatNote=WD 6
TgeneLLGL2chr17:73723586chr17:73552127ENST00000375227110332_36625.0357.0RepeatNote=WD 7
TgeneLLGL2chr17:73723586chr17:73552127ENST0000037522711036_6925.0357.0RepeatNote=WD 1
TgeneLLGL2chr17:73723586chr17:73552127ENST00000375227110388_46425.0357.0RepeatNote=WD 8
TgeneLLGL2chr17:73723586chr17:73552127ENST00000375227110508_58325.0357.0RepeatNote=WD 9
TgeneLLGL2chr17:73723586chr17:73552127ENST00000375227110592_65325.0357.0RepeatNote=WD 10
TgeneLLGL2chr17:73723586chr17:73552127ENST00000375227110713_76925.0357.0RepeatNote=WD 11
TgeneLLGL2chr17:73723586chr17:73552127ENST0000037522711076_11725.0357.0RepeatNote=WD 2
TgeneLLGL2chr17:73723586chr17:73552127ENST00000375227110778_83025.0357.0RepeatNote=WD 12
TgeneLLGL2chr17:73723586chr17:73552127ENST00000375227110835_88825.0357.0RepeatNote=WD 13
TgeneLLGL2chr17:73723586chr17:73552127ENST00000375227110902_92525.0357.0RepeatNote=WD 14
TgeneLLGL2chr17:73723586chr17:73552127ENST00000392550126132_16925.01021.0RepeatNote=WD 3
TgeneLLGL2chr17:73723586chr17:73552127ENST00000392550126193_22725.01021.0RepeatNote=WD 4
TgeneLLGL2chr17:73723586chr17:73552127ENST00000392550126233_26825.01021.0RepeatNote=WD 5
TgeneLLGL2chr17:73723586chr17:73552127ENST00000392550126282_32425.01021.0RepeatNote=WD 6
TgeneLLGL2chr17:73723586chr17:73552127ENST00000392550126332_36625.01021.0RepeatNote=WD 7
TgeneLLGL2chr17:73723586chr17:73552127ENST0000039255012636_6925.01021.0RepeatNote=WD 1
TgeneLLGL2chr17:73723586chr17:73552127ENST00000392550126388_46425.01021.0RepeatNote=WD 8
TgeneLLGL2chr17:73723586chr17:73552127ENST00000392550126508_58325.01021.0RepeatNote=WD 9
TgeneLLGL2chr17:73723586chr17:73552127ENST00000392550126592_65325.01021.0RepeatNote=WD 10
TgeneLLGL2chr17:73723586chr17:73552127ENST00000392550126713_76925.01021.0RepeatNote=WD 11
TgeneLLGL2chr17:73723586chr17:73552127ENST0000039255012676_11725.01021.0RepeatNote=WD 2
TgeneLLGL2chr17:73723586chr17:73552127ENST00000392550126778_83025.01021.0RepeatNote=WD 12
TgeneLLGL2chr17:73723586chr17:73552127ENST00000392550126835_88825.01021.0RepeatNote=WD 13
TgeneLLGL2chr17:73723586chr17:73552127ENST00000392550126902_92525.01021.0RepeatNote=WD 14
TgeneLLGL2chr17:73723586chr17:73552127ENST00000578363211132_16925.0357.0RepeatNote=WD 3
TgeneLLGL2chr17:73723586chr17:73552127ENST00000578363211193_22725.0357.0RepeatNote=WD 4
TgeneLLGL2chr17:73723586chr17:73552127ENST00000578363211233_26825.0357.0RepeatNote=WD 5
TgeneLLGL2chr17:73723586chr17:73552127ENST00000578363211282_32425.0357.0RepeatNote=WD 6
TgeneLLGL2chr17:73723586chr17:73552127ENST00000578363211332_36625.0357.0RepeatNote=WD 7
TgeneLLGL2chr17:73723586chr17:73552127ENST0000057836321136_6925.0357.0RepeatNote=WD 1
TgeneLLGL2chr17:73723586chr17:73552127ENST00000578363211388_46425.0357.0RepeatNote=WD 8
TgeneLLGL2chr17:73723586chr17:73552127ENST00000578363211508_58325.0357.0RepeatNote=WD 9
TgeneLLGL2chr17:73723586chr17:73552127ENST00000578363211592_65325.0357.0RepeatNote=WD 10
TgeneLLGL2chr17:73723586chr17:73552127ENST00000578363211713_76925.0357.0RepeatNote=WD 11
TgeneLLGL2chr17:73723586chr17:73552127ENST0000057836321176_11725.0357.0RepeatNote=WD 2
TgeneLLGL2chr17:73723586chr17:73552127ENST00000578363211778_83025.0357.0RepeatNote=WD 12
TgeneLLGL2chr17:73723586chr17:73552127ENST00000578363211835_88825.0357.0RepeatNote=WD 13
TgeneLLGL2chr17:73723586chr17:73552127ENST00000578363211902_92525.0357.0RepeatNote=WD 14

- Not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneITGB4chr17:73723586chr17:73552126ENST00000200181+4401129_121888.01823.0DomainFibronectin type-III 1
HgeneITGB4chr17:73723586chr17:73552126ENST00000200181+4401222_132188.01823.0DomainFibronectin type-III 2
HgeneITGB4chr17:73723586chr17:73552126ENST00000200181+440131_32988.01823.0DomainNote=VWFA
HgeneITGB4chr17:73723586chr17:73552126ENST00000200181+4401530_162588.01823.0DomainFibronectin type-III 3
HgeneITGB4chr17:73723586chr17:73552126ENST00000200181+4401643_173988.01823.0DomainFibronectin type-III 4
HgeneITGB4chr17:73723586chr17:73552126ENST00000200181+440979_108488.01823.0DomainNote=Calx-beta
HgeneITGB4chr17:73723586chr17:73552126ENST00000339591+4401129_121888.01806.0DomainFibronectin type-III 1
HgeneITGB4chr17:73723586chr17:73552126ENST00000339591+4401222_132188.01806.0DomainFibronectin type-III 2
HgeneITGB4chr17:73723586chr17:73552126ENST00000339591+440131_32988.01806.0DomainNote=VWFA
HgeneITGB4chr17:73723586chr17:73552126ENST00000339591+4401530_162588.01806.0DomainFibronectin type-III 3
HgeneITGB4chr17:73723586chr17:73552126ENST00000339591+4401643_173988.01806.0DomainFibronectin type-III 4
HgeneITGB4chr17:73723586chr17:73552126ENST00000339591+440979_108488.01806.0DomainNote=Calx-beta
HgeneITGB4chr17:73723586chr17:73552126ENST00000449880+3391129_121888.01806.0DomainFibronectin type-III 1
HgeneITGB4chr17:73723586chr17:73552126ENST00000449880+3391222_132188.01806.0DomainFibronectin type-III 2
HgeneITGB4chr17:73723586chr17:73552126ENST00000449880+339131_32988.01806.0DomainNote=VWFA
HgeneITGB4chr17:73723586chr17:73552126ENST00000449880+3391530_162588.01806.0DomainFibronectin type-III 3
HgeneITGB4chr17:73723586chr17:73552126ENST00000449880+3391643_173988.01806.0DomainFibronectin type-III 4
HgeneITGB4chr17:73723586chr17:73552126ENST00000449880+339979_108488.01806.0DomainNote=Calx-beta
HgeneITGB4chr17:73723586chr17:73552126ENST00000450894+4391129_121888.01753.0DomainFibronectin type-III 1
HgeneITGB4chr17:73723586chr17:73552126ENST00000450894+4391222_132188.01753.0DomainFibronectin type-III 2
HgeneITGB4chr17:73723586chr17:73552126ENST00000450894+439131_32988.01753.0DomainNote=VWFA
HgeneITGB4chr17:73723586chr17:73552126ENST00000450894+4391530_162588.01753.0DomainFibronectin type-III 3
HgeneITGB4chr17:73723586chr17:73552126ENST00000450894+4391643_173988.01753.0DomainFibronectin type-III 4
HgeneITGB4chr17:73723586chr17:73552126ENST00000450894+439979_108488.01753.0DomainNote=Calx-beta
HgeneITGB4chr17:73723586chr17:73552126ENST00000579662+4391129_121888.01753.0DomainFibronectin type-III 1
HgeneITGB4chr17:73723586chr17:73552126ENST00000579662+4391222_132188.01753.0DomainFibronectin type-III 2
HgeneITGB4chr17:73723586chr17:73552126ENST00000579662+439131_32988.01753.0DomainNote=VWFA
HgeneITGB4chr17:73723586chr17:73552126ENST00000579662+4391530_162588.01753.0DomainFibronectin type-III 3
HgeneITGB4chr17:73723586chr17:73552126ENST00000579662+4391643_173988.01753.0DomainFibronectin type-III 4
HgeneITGB4chr17:73723586chr17:73552126ENST00000579662+439979_108488.01753.0DomainNote=Calx-beta
HgeneITGB4chr17:73723586chr17:73552127ENST00000200181+4401129_121888.01823.0DomainFibronectin type-III 1
HgeneITGB4chr17:73723586chr17:73552127ENST00000200181+4401222_132188.01823.0DomainFibronectin type-III 2
HgeneITGB4chr17:73723586chr17:73552127ENST00000200181+440131_32988.01823.0DomainNote=VWFA
HgeneITGB4chr17:73723586chr17:73552127ENST00000200181+4401530_162588.01823.0DomainFibronectin type-III 3
HgeneITGB4chr17:73723586chr17:73552127ENST00000200181+4401643_173988.01823.0DomainFibronectin type-III 4
HgeneITGB4chr17:73723586chr17:73552127ENST00000200181+440979_108488.01823.0DomainNote=Calx-beta
HgeneITGB4chr17:73723586chr17:73552127ENST00000339591+4401129_121888.01806.0DomainFibronectin type-III 1
HgeneITGB4chr17:73723586chr17:73552127ENST00000339591+4401222_132188.01806.0DomainFibronectin type-III 2
HgeneITGB4chr17:73723586chr17:73552127ENST00000339591+440131_32988.01806.0DomainNote=VWFA
HgeneITGB4chr17:73723586chr17:73552127ENST00000339591+4401530_162588.01806.0DomainFibronectin type-III 3
HgeneITGB4chr17:73723586chr17:73552127ENST00000339591+4401643_173988.01806.0DomainFibronectin type-III 4
HgeneITGB4chr17:73723586chr17:73552127ENST00000339591+440979_108488.01806.0DomainNote=Calx-beta
HgeneITGB4chr17:73723586chr17:73552127ENST00000449880+3391129_121888.01806.0DomainFibronectin type-III 1
HgeneITGB4chr17:73723586chr17:73552127ENST00000449880+3391222_132188.01806.0DomainFibronectin type-III 2
HgeneITGB4chr17:73723586chr17:73552127ENST00000449880+339131_32988.01806.0DomainNote=VWFA
HgeneITGB4chr17:73723586chr17:73552127ENST00000449880+3391530_162588.01806.0DomainFibronectin type-III 3
HgeneITGB4chr17:73723586chr17:73552127ENST00000449880+3391643_173988.01806.0DomainFibronectin type-III 4
HgeneITGB4chr17:73723586chr17:73552127ENST00000449880+339979_108488.01806.0DomainNote=Calx-beta
HgeneITGB4chr17:73723586chr17:73552127ENST00000450894+4391129_121888.01753.0DomainFibronectin type-III 1
HgeneITGB4chr17:73723586chr17:73552127ENST00000450894+4391222_132188.01753.0DomainFibronectin type-III 2
HgeneITGB4chr17:73723586chr17:73552127ENST00000450894+439131_32988.01753.0DomainNote=VWFA
HgeneITGB4chr17:73723586chr17:73552127ENST00000450894+4391530_162588.01753.0DomainFibronectin type-III 3
HgeneITGB4chr17:73723586chr17:73552127ENST00000450894+4391643_173988.01753.0DomainFibronectin type-III 4
HgeneITGB4chr17:73723586chr17:73552127ENST00000450894+439979_108488.01753.0DomainNote=Calx-beta
HgeneITGB4chr17:73723586chr17:73552127ENST00000579662+4391129_121888.01753.0DomainFibronectin type-III 1
HgeneITGB4chr17:73723586chr17:73552127ENST00000579662+4391222_132188.01753.0DomainFibronectin type-III 2
HgeneITGB4chr17:73723586chr17:73552127ENST00000579662+439131_32988.01753.0DomainNote=VWFA
HgeneITGB4chr17:73723586chr17:73552127ENST00000579662+4391530_162588.01753.0DomainFibronectin type-III 3
HgeneITGB4chr17:73723586chr17:73552127ENST00000579662+4391643_173988.01753.0DomainFibronectin type-III 4
HgeneITGB4chr17:73723586chr17:73552127ENST00000579662+439979_108488.01753.0DomainNote=Calx-beta
HgeneITGB4chr17:73723586chr17:73552126ENST00000200181+440194_19988.01823.0RegionInvolved in NRG1- and IGF1-binding
HgeneITGB4chr17:73723586chr17:73552126ENST00000200181+440456_61988.01823.0RegionNote=Cysteine-rich tandem repeats
HgeneITGB4chr17:73723586chr17:73552126ENST00000200181+440732_74988.01823.0RegionNote=Palmitoylated on several cysteines
HgeneITGB4chr17:73723586chr17:73552126ENST00000339591+440194_19988.01806.0RegionInvolved in NRG1- and IGF1-binding
HgeneITGB4chr17:73723586chr17:73552126ENST00000339591+440456_61988.01806.0RegionNote=Cysteine-rich tandem repeats
HgeneITGB4chr17:73723586chr17:73552126ENST00000339591+440732_74988.01806.0RegionNote=Palmitoylated on several cysteines
HgeneITGB4chr17:73723586chr17:73552126ENST00000449880+339194_19988.01806.0RegionInvolved in NRG1- and IGF1-binding
HgeneITGB4chr17:73723586chr17:73552126ENST00000449880+339456_61988.01806.0RegionNote=Cysteine-rich tandem repeats
HgeneITGB4chr17:73723586chr17:73552126ENST00000449880+339732_74988.01806.0RegionNote=Palmitoylated on several cysteines
HgeneITGB4chr17:73723586chr17:73552126ENST00000450894+439194_19988.01753.0RegionInvolved in NRG1- and IGF1-binding
HgeneITGB4chr17:73723586chr17:73552126ENST00000450894+439456_61988.01753.0RegionNote=Cysteine-rich tandem repeats
HgeneITGB4chr17:73723586chr17:73552126ENST00000450894+439732_74988.01753.0RegionNote=Palmitoylated on several cysteines
HgeneITGB4chr17:73723586chr17:73552126ENST00000579662+439194_19988.01753.0RegionInvolved in NRG1- and IGF1-binding
HgeneITGB4chr17:73723586chr17:73552126ENST00000579662+439456_61988.01753.0RegionNote=Cysteine-rich tandem repeats
HgeneITGB4chr17:73723586chr17:73552126ENST00000579662+439732_74988.01753.0RegionNote=Palmitoylated on several cysteines
HgeneITGB4chr17:73723586chr17:73552127ENST00000200181+440194_19988.01823.0RegionInvolved in NRG1- and IGF1-binding
HgeneITGB4chr17:73723586chr17:73552127ENST00000200181+440456_61988.01823.0RegionNote=Cysteine-rich tandem repeats
HgeneITGB4chr17:73723586chr17:73552127ENST00000200181+440732_74988.01823.0RegionNote=Palmitoylated on several cysteines
HgeneITGB4chr17:73723586chr17:73552127ENST00000339591+440194_19988.01806.0RegionInvolved in NRG1- and IGF1-binding
HgeneITGB4chr17:73723586chr17:73552127ENST00000339591+440456_61988.01806.0RegionNote=Cysteine-rich tandem repeats
HgeneITGB4chr17:73723586chr17:73552127ENST00000339591+440732_74988.01806.0RegionNote=Palmitoylated on several cysteines
HgeneITGB4chr17:73723586chr17:73552127ENST00000449880+339194_19988.01806.0RegionInvolved in NRG1- and IGF1-binding
HgeneITGB4chr17:73723586chr17:73552127ENST00000449880+339456_61988.01806.0RegionNote=Cysteine-rich tandem repeats
HgeneITGB4chr17:73723586chr17:73552127ENST00000449880+339732_74988.01806.0RegionNote=Palmitoylated on several cysteines
HgeneITGB4chr17:73723586chr17:73552127ENST00000450894+439194_19988.01753.0RegionInvolved in NRG1- and IGF1-binding
HgeneITGB4chr17:73723586chr17:73552127ENST00000450894+439456_61988.01753.0RegionNote=Cysteine-rich tandem repeats
HgeneITGB4chr17:73723586chr17:73552127ENST00000450894+439732_74988.01753.0RegionNote=Palmitoylated on several cysteines
HgeneITGB4chr17:73723586chr17:73552127ENST00000579662+439194_19988.01753.0RegionInvolved in NRG1- and IGF1-binding
HgeneITGB4chr17:73723586chr17:73552127ENST00000579662+439456_61988.01753.0RegionNote=Cysteine-rich tandem repeats
HgeneITGB4chr17:73723586chr17:73552127ENST00000579662+439732_74988.01753.0RegionNote=Palmitoylated on several cysteines
HgeneITGB4chr17:73723586chr17:73552126ENST00000200181+440456_50288.01823.0RepeatNote=I
HgeneITGB4chr17:73723586chr17:73552126ENST00000200181+440503_54288.01823.0RepeatNote=II
HgeneITGB4chr17:73723586chr17:73552126ENST00000200181+440543_58188.01823.0RepeatNote=III
HgeneITGB4chr17:73723586chr17:73552126ENST00000200181+440582_61988.01823.0RepeatNote=IV
HgeneITGB4chr17:73723586chr17:73552126ENST00000339591+440456_50288.01806.0RepeatNote=I
HgeneITGB4chr17:73723586chr17:73552126ENST00000339591+440503_54288.01806.0RepeatNote=II
HgeneITGB4chr17:73723586chr17:73552126ENST00000339591+440543_58188.01806.0RepeatNote=III
HgeneITGB4chr17:73723586chr17:73552126ENST00000339591+440582_61988.01806.0RepeatNote=IV
HgeneITGB4chr17:73723586chr17:73552126ENST00000449880+339456_50288.01806.0RepeatNote=I
HgeneITGB4chr17:73723586chr17:73552126ENST00000449880+339503_54288.01806.0RepeatNote=II
HgeneITGB4chr17:73723586chr17:73552126ENST00000449880+339543_58188.01806.0RepeatNote=III
HgeneITGB4chr17:73723586chr17:73552126ENST00000449880+339582_61988.01806.0RepeatNote=IV
HgeneITGB4chr17:73723586chr17:73552126ENST00000450894+439456_50288.01753.0RepeatNote=I
HgeneITGB4chr17:73723586chr17:73552126ENST00000450894+439503_54288.01753.0RepeatNote=II
HgeneITGB4chr17:73723586chr17:73552126ENST00000450894+439543_58188.01753.0RepeatNote=III
HgeneITGB4chr17:73723586chr17:73552126ENST00000450894+439582_61988.01753.0RepeatNote=IV
HgeneITGB4chr17:73723586chr17:73552126ENST00000579662+439456_50288.01753.0RepeatNote=I
HgeneITGB4chr17:73723586chr17:73552126ENST00000579662+439503_54288.01753.0RepeatNote=II
HgeneITGB4chr17:73723586chr17:73552126ENST00000579662+439543_58188.01753.0RepeatNote=III
HgeneITGB4chr17:73723586chr17:73552126ENST00000579662+439582_61988.01753.0RepeatNote=IV
HgeneITGB4chr17:73723586chr17:73552127ENST00000200181+440456_50288.01823.0RepeatNote=I
HgeneITGB4chr17:73723586chr17:73552127ENST00000200181+440503_54288.01823.0RepeatNote=II
HgeneITGB4chr17:73723586chr17:73552127ENST00000200181+440543_58188.01823.0RepeatNote=III
HgeneITGB4chr17:73723586chr17:73552127ENST00000200181+440582_61988.01823.0RepeatNote=IV
HgeneITGB4chr17:73723586chr17:73552127ENST00000339591+440456_50288.01806.0RepeatNote=I
HgeneITGB4chr17:73723586chr17:73552127ENST00000339591+440503_54288.01806.0RepeatNote=II
HgeneITGB4chr17:73723586chr17:73552127ENST00000339591+440543_58188.01806.0RepeatNote=III
HgeneITGB4chr17:73723586chr17:73552127ENST00000339591+440582_61988.01806.0RepeatNote=IV
HgeneITGB4chr17:73723586chr17:73552127ENST00000449880+339456_50288.01806.0RepeatNote=I
HgeneITGB4chr17:73723586chr17:73552127ENST00000449880+339503_54288.01806.0RepeatNote=II
HgeneITGB4chr17:73723586chr17:73552127ENST00000449880+339543_58188.01806.0RepeatNote=III
HgeneITGB4chr17:73723586chr17:73552127ENST00000449880+339582_61988.01806.0RepeatNote=IV
HgeneITGB4chr17:73723586chr17:73552127ENST00000450894+439456_50288.01753.0RepeatNote=I
HgeneITGB4chr17:73723586chr17:73552127ENST00000450894+439503_54288.01753.0RepeatNote=II
HgeneITGB4chr17:73723586chr17:73552127ENST00000450894+439543_58188.01753.0RepeatNote=III
HgeneITGB4chr17:73723586chr17:73552127ENST00000450894+439582_61988.01753.0RepeatNote=IV
HgeneITGB4chr17:73723586chr17:73552127ENST00000579662+439456_50288.01753.0RepeatNote=I
HgeneITGB4chr17:73723586chr17:73552127ENST00000579662+439503_54288.01753.0RepeatNote=II
HgeneITGB4chr17:73723586chr17:73552127ENST00000579662+439543_58188.01753.0RepeatNote=III
HgeneITGB4chr17:73723586chr17:73552127ENST00000579662+439582_61988.01753.0RepeatNote=IV
HgeneITGB4chr17:73723586chr17:73552126ENST00000200181+44028_71088.01823.0Topological domainExtracellular
HgeneITGB4chr17:73723586chr17:73552126ENST00000200181+440734_182288.01823.0Topological domainCytoplasmic
HgeneITGB4chr17:73723586chr17:73552126ENST00000339591+44028_71088.01806.0Topological domainExtracellular
HgeneITGB4chr17:73723586chr17:73552126ENST00000339591+440734_182288.01806.0Topological domainCytoplasmic
HgeneITGB4chr17:73723586chr17:73552126ENST00000449880+33928_71088.01806.0Topological domainExtracellular
HgeneITGB4chr17:73723586chr17:73552126ENST00000449880+339734_182288.01806.0Topological domainCytoplasmic
HgeneITGB4chr17:73723586chr17:73552126ENST00000450894+43928_71088.01753.0Topological domainExtracellular
HgeneITGB4chr17:73723586chr17:73552126ENST00000450894+439734_182288.01753.0Topological domainCytoplasmic
HgeneITGB4chr17:73723586chr17:73552126ENST00000579662+43928_71088.01753.0Topological domainExtracellular
HgeneITGB4chr17:73723586chr17:73552126ENST00000579662+439734_182288.01753.0Topological domainCytoplasmic
HgeneITGB4chr17:73723586chr17:73552127ENST00000200181+44028_71088.01823.0Topological domainExtracellular
HgeneITGB4chr17:73723586chr17:73552127ENST00000200181+440734_182288.01823.0Topological domainCytoplasmic
HgeneITGB4chr17:73723586chr17:73552127ENST00000339591+44028_71088.01806.0Topological domainExtracellular
HgeneITGB4chr17:73723586chr17:73552127ENST00000339591+440734_182288.01806.0Topological domainCytoplasmic
HgeneITGB4chr17:73723586chr17:73552127ENST00000449880+33928_71088.01806.0Topological domainExtracellular
HgeneITGB4chr17:73723586chr17:73552127ENST00000449880+339734_182288.01806.0Topological domainCytoplasmic
HgeneITGB4chr17:73723586chr17:73552127ENST00000450894+43928_71088.01753.0Topological domainExtracellular
HgeneITGB4chr17:73723586chr17:73552127ENST00000450894+439734_182288.01753.0Topological domainCytoplasmic
HgeneITGB4chr17:73723586chr17:73552127ENST00000579662+43928_71088.01753.0Topological domainExtracellular
HgeneITGB4chr17:73723586chr17:73552127ENST00000579662+439734_182288.01753.0Topological domainCytoplasmic
HgeneITGB4chr17:73723586chr17:73552126ENST00000200181+440711_73388.01823.0TransmembraneHelical
HgeneITGB4chr17:73723586chr17:73552126ENST00000339591+440711_73388.01806.0TransmembraneHelical
HgeneITGB4chr17:73723586chr17:73552126ENST00000449880+339711_73388.01806.0TransmembraneHelical
HgeneITGB4chr17:73723586chr17:73552126ENST00000450894+439711_73388.01753.0TransmembraneHelical
HgeneITGB4chr17:73723586chr17:73552126ENST00000579662+439711_73388.01753.0TransmembraneHelical
HgeneITGB4chr17:73723586chr17:73552127ENST00000200181+440711_73388.01823.0TransmembraneHelical
HgeneITGB4chr17:73723586chr17:73552127ENST00000339591+440711_73388.01806.0TransmembraneHelical
HgeneITGB4chr17:73723586chr17:73552127ENST00000449880+339711_73388.01806.0TransmembraneHelical
HgeneITGB4chr17:73723586chr17:73552127ENST00000450894+439711_73388.01753.0TransmembraneHelical
HgeneITGB4chr17:73723586chr17:73552127ENST00000579662+439711_73388.01753.0TransmembraneHelical


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Fusion Protein-Protein Interaction


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type from validated records (BIOGRID-3.4.160)
GenePPI interactors


check button Protein-protein interactors based on sequence similarity (STRING)
GeneSTRING network
ITGB4
LLGL2


check button - Retained interactions in fusion protein (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost interactions due to fusion (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs to ITGB4-LLGL2


check button Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDrugSourcePMID

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Related Diseases to ITGB4-LLGL2


check button Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDiseaseSourcePMID

check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource