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Center for Computational Systems Medicine level1
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Fusion Gene Summary

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Fusion Gene Sample Information

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Fusion ORF Analysis

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Fusion Amino Acid Sequences

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Fusion Protein Functional Features

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Fusion Protein-Protein Interaction

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Related drugs with this fusion protein

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Related disease with this fusion protein

Fusion Protein:KCNK5-PDE4DIP

Fusion Protein Summary

check button Fusion gene summary
Fusion partner gene informationFusion gene name: KCNK5-PDE4DIP
FusionPDB ID: 41474
FusionGDB2.0 ID: 41474
HgeneTgene
Gene symbol

KCNK5

PDE4DIP

Gene ID

8645

9659

Gene namepotassium two pore domain channel subfamily K member 5phosphodiesterase 4D interacting protein
SynonymsK2p5.1|KCNK5b|TASK-2|TASK2CMYA2|MMGL
Cytomap

6p21.2

1q21.2

Type of geneprotein-codingprotein-coding
Descriptionpotassium channel subfamily K member 5K2P5.1 potassium channelTWIK-related acid-sensitive K(+) channel 2TWIK-related acid-sensitive K+ 2TWIK-related acid-sensitive K+ channel 2acid-sensitive potassium channel protein TASK-2potassium channel, subfamimyomegalincardiomyopathy-associated protein 2myomegalin/phosphodiesterase 4D interacting protein variant 8
Modification date2020031320200313
UniProtAcc

O95279

.
Ensembl transtripts involved in fusion geneENST idsENST00000359534, ENST00000313431, 
ENST00000369345, ENST00000478649, 
ENST00000479408, ENST00000493130, 
ENST00000524974, ENST00000529945, 
ENST00000313382, ENST00000369347, 
ENST00000369348, ENST00000369349, 
ENST00000369351, ENST00000369354, 
ENST00000369356, ENST00000369359, 
ENST00000530740, 
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)* DoF score3 X 2 X 3=1812 X 9 X 8=864
# samples 313
** MAII scorelog2(3/18*10)=0.736965594166206
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(13/864*10)=-2.73251968913501
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context (manual curation of fusion genes in FusionPDB)

PubMed: KCNK5 [Title/Abstract] AND PDE4DIP [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)KCNK5(39196702)-PDE4DIP(144994701), # samples:3
Anticipated loss of major functional domain due to fusion event.KCNK5-PDE4DIP seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
KCNK5-PDE4DIP seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgenePDE4DIP

GO:1903358

regulation of Golgi organization

27666745


check buttonFusion gene breakpoints across KCNK5 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across PDE4DIP (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure


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Fusion Gene Sample Information

check buttonFusion gene information from FusionGDB2.0.
check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUADTCGA-91-A4BC-01AKCNK5chr6

39196702

-PDE4DIPchr1

144994701

-
ChimerDB4LUADTCGA-91-A4BC-01AKCNK5chr6

39196702

-PDE4DIPchr1

144994701

+


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Fusion ORF Analysis


check buttonFusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000359534KCNK5chr639196702-ENST00000313382PDE4DIPchr1144994701+805452533970192226
ENST00000359534KCNK5chr639196702-ENST00000369354PDE4DIPchr1144994701+856752564677969500
ENST00000359534KCNK5chr639196702-ENST00000369356PDE4DIPchr1144994701+851152564117913500
ENST00000359534KCNK5chr639196702-ENST00000530740PDE4DIPchr1144994701+835052533973792346
ENST00000359534KCNK5chr639196702-ENST00000369359PDE4DIPchr1144994701+850352533975322397
ENST00000359534KCNK5chr639196702-ENST00000369351PDE4DIPchr1144994701+530852532084710500
ENST00000359534KCNK5chr639196702-ENST00000369349PDE4DIPchr1144994701+502752529274429500
ENST00000359534KCNK5chr639196702-ENST00000369347PDE4DIPchr1144994701+1454525339704121
ENST00000359534KCNK5chr639196702-ENST00000369348PDE4DIPchr1144994701+14505253391016225

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000359534ENST00000313382KCNK5chr639196702-PDE4DIPchr1144994701+0.007725830.9922741
ENST00000359534ENST00000369354KCNK5chr639196702-PDE4DIPchr1144994701+0.0047955860.99520445
ENST00000359534ENST00000369356KCNK5chr639196702-PDE4DIPchr1144994701+0.0049167410.99508333
ENST00000359534ENST00000530740KCNK5chr639196702-PDE4DIPchr1144994701+0.0067002440.9932997
ENST00000359534ENST00000369359KCNK5chr639196702-PDE4DIPchr1144994701+0.0058642150.99413574
ENST00000359534ENST00000369351KCNK5chr639196702-PDE4DIPchr1144994701+0.0047434620.9952565
ENST00000359534ENST00000369349KCNK5chr639196702-PDE4DIPchr1144994701+0.0058774820.99412256
ENST00000359534ENST00000369347KCNK5chr639196702-PDE4DIPchr1144994701+0.0082159420.9917841
ENST00000359534ENST00000369348KCNK5chr639196702-PDE4DIPchr1144994701+0.0007498870.9992501

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Fusion Amino Acid Sequences


check button For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

>41474_41474_1_KCNK5-PDE4DIP_KCNK5_chr6_39196702_ENST00000359534_PDE4DIP_chr1_144994701_ENST00000313382_length(amino acids)=2226AA_BP=62
MVDRGPLLTSAIIFYLAIGAAIFEVLEEPHWKEAKKNYYTQKLHLLKEFPCLGQEGLDKILEHLNDLKKENFSLKLRIYFLEERMQQKYE
ASREDIYKRNIELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAARMAA
LVEAEKECNLELSEKLKGVTKNWEDVPGDQVKPDQYTEALAQRDKRIEELNQSLAAQERLVEQLSREKQQLLHLLEEPTSMEVQPMTEEL
LKQQKLNSHETTITQQSVSDSHLAELQEKIQQTEATNKILQEKLNEMSYELKCAQESSQKQDGTIQNLKETLKSRERETEELYQVIEGQN
DTMAKLREMLHQSQLGQLHSSEGTSPAQQQVALLDLQSALFCSQLEIQKLQRVVRQKERQLADAKQCVQFVEAAAHESEQQKEASWKHNQ
ELRKALQQLQEELQNKSQQLRAWEAEKYNEIRTQEQNIQHLNHSLSHKEQLLQEFRELLQYRDNSDKTLEANEMLLEKLRQRIHDKAVAL
ERAIDEKFSALEEKEKELRQLRLAVRERDHDLERLRDVLSSNEATMQSMESLLRAKGLEVEQLSTTCQNLQWLKEEMETKFSRWQKEQES
IIQQLQTSLHDRNKEVEDLSATLLCKLGPGQSEIAEELCQRLQRKERMLQDLLSDRNKQVLEHEMEIQGLLQSVSTREQESQAAAEKLVQ
ALMERNSELQALRQYLGGRDSLMSQAPISNQQAEVTPTGCLGKQTDQGSMQIPSRDDSTSLTAKEDVSIPRSTLGDLDTVAGLEKELSNA
KEELELMAKKERESQMELSALQSMMAVQEEELQVQAADMESLTRNIQIKEDLIKDLQMQLVDPEDIPAMERLTQEVLLLREKVASVESQG
QEISGNRRQQLLLMLEGLVDERSRLNEALQAERQLYSSLVKFHAHPESSERDRTLQVELEGAQVLRSRLEEVLGRSLERLNRLETLAAIG
GAAAGDDTEDTSTEFTDSIEEEAAHHSHQQLVKVALEKSLATVETQNPSFSPPSPMGGDSNRCLQEEMLHLRAEFHQHLEEKRKAEEELK
ELKAQIEEAGFSSVSHIRNTMLSLCLENAELKEQMGEAMSDGWEIEEDKEKGELDNQSQPRDPGPQSAFSLPGSTQHLRSQLSQCKQRYQ
DLQEKLLLSEATVFAQANELEKYRVMLTGESLVKQDSKQIQVDLQDLGYETCGRSENEAEREETTSPECEEHNSLKEMVLMEGLCSEQGR
RGSTLASSSERKPLENQLGKQEEFRVYGKSENILVLRKDIKDLKAQLQNANKVIQNLKSRVRSLSVTSDYSSSLERPWKLRAVGTLEGSS
PHSVPDEDEGWLSDGTGAFYSPGLQAKKDLESLIQRVSQLEAQLPKNGLEEKLAEELRSASWPGKYDSLIQDQARELSYLRQKIREGRGI
CYLITRHAKDTVKSFEDLLRSNDIDYYLGQSFREQLAQGSQLTERLTSKLSTKDHKSEKDQAGLEPLALRLSRELQEKEKVIEVLQAKLD
ARSLTPSSSHALSDSHRSPSSTSFLSDELEACSDMDIVSEYTHYEEKKASPSHSDSIHHSSHSAVLSSKPSSTSASQGAKAESNSNPISL
PTPQNTPKEANQAHSGASTVPPASTATLLSNDLEADSSYYLNSAQPHSPPRGTIELGRILEPGYLGSSGKWDVMRPQKGSVSGDLSSGSS
VYQLNSKPTGADLLEEHLGEIRNLRQRLEESICINDRLREQLEHRLTSTARGRGSTSNFYSQGLESIPQLCNENRVLREDNRRLQAQLSH
VSREHSQETESLREALLSSRSHLQELEKELEHQKVERQQLLEDLREKQQEVLHFREERLSLQENDSRLQHKLVLLQQQCEEKQQLFESLQ
SELQIYEALYGNSKKGLKAYSLDACHQIPLSSDLSHLVAEVRALRGQLEQSIQGNNCLRLQLQQQLESGAGKASLSPSSINQNFPASTDP
GNKQLLLQDSAVSPPVRDVGMNSPALVFPSSASSTPGSETPIINRANGLGLDTSPVMKTPPKLEGDATDGSFANKHGRHVIGHIDDYSAL
RQQIAEGKLLVKKIVSLVRSACSFPGLEAQGTEVLGSKGIHELRSSTSALHHALEESASLLTMFWRAALPSTHIPVLPGKVGESTERELL

--------------------------------------------------------------

>41474_41474_2_KCNK5-PDE4DIP_KCNK5_chr6_39196702_ENST00000359534_PDE4DIP_chr1_144994701_ENST00000369347_length(amino acids)=121AA_BP=
MVDRGPLLTSAIIFYLAIGAAIFEVLEEPHWKEAKKNYYTQKLHLLKEFPCLGQEGLDKILEESRLAKNEAARMAALVEAEKECNLELSE

--------------------------------------------------------------

>41474_41474_3_KCNK5-PDE4DIP_KCNK5_chr6_39196702_ENST00000359534_PDE4DIP_chr1_144994701_ENST00000369348_length(amino acids)=225AA_BP=62
MVDRGPLLTSAIIFYLAIGAAIFEVLEEPHWKEAKKNYYTQKLHLLKEFPCLGQEGLDKILEHLNDLKKENFSLKLRIYFLEERMQQKYE
ASREDIYKRNIELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAARMAA

--------------------------------------------------------------

>41474_41474_4_KCNK5-PDE4DIP_KCNK5_chr6_39196702_ENST00000359534_PDE4DIP_chr1_144994701_ENST00000369349_length(amino acids)=500AA_BP=0
MVQALMERNSELQALRQYLGGRDSLMSQAPISNQQAEVTPTGCLGKQTDQDLSATLLCKLGPGQSEIAEELCQRLQRKERMLQDLLSDRN
KQVLEHEMEIQGLLQSVSTREQESQSMESLLRAKGLEVEQLSTTCQNLQWLKEEMETKFSRWQKEQESIIQQLQTSLHDRNKEVERAIDE
KFSALEEKEKELRQLRLAVRERDHDLERLRDVLSSNEATMQEFRELLQYRDNSDKTLEANEMLLEKLRQRIHDKAVALEELRKALQQLQE
ELQNKSQQLRAWEAEKYNEIRTQEQNIQHLNHSLSHKEQLLQSSEGTSPAQQQVALLDLQSALFCSQLEIQKLQRVVRQKERQLADAKQC
VQFVEAAAHESEQQKEASWKHNQTEELYQVIEGQNDTMAKLREMLHQSQLGQLHILQEKLNEMSYELKCAQESSQKQDGTIQNLKETLKS

--------------------------------------------------------------

>41474_41474_5_KCNK5-PDE4DIP_KCNK5_chr6_39196702_ENST00000359534_PDE4DIP_chr1_144994701_ENST00000369351_length(amino acids)=500AA_BP=0
MVQALMERNSELQALRQYLGGRDSLMSQAPISNQQAEVTPTGCLGKQTDQDLSATLLCKLGPGQSEIAEELCQRLQRKERMLQDLLSDRN
KQVLEHEMEIQGLLQSVSTREQESQSMESLLRAKGLEVEQLSTTCQNLQWLKEEMETKFSRWQKEQESIIQQLQTSLHDRNKEVERAIDE
KFSALEEKEKELRQLRLAVRERDHDLERLRDVLSSNEATMQEFRELLQYRDNSDKTLEANEMLLEKLRQRIHDKAVALEELRKALQQLQE
ELQNKSQQLRAWEAEKYNEIRTQEQNIQHLNHSLSHKEQLLQSSEGTSPAQQQVALLDLQSALFCSQLEIQKLQRVVRQKERQLADAKQC
VQFVEAAAHESEQQKEASWKHNQTEELYQVIEGQNDTMAKLREMLHQSQLGQLHILQEKLNEMSYELKCAQESSQKQDGTIQNLKETLKS

--------------------------------------------------------------

>41474_41474_6_KCNK5-PDE4DIP_KCNK5_chr6_39196702_ENST00000359534_PDE4DIP_chr1_144994701_ENST00000369354_length(amino acids)=500AA_BP=0
MVQALMERNSELQALRQYLGGRDSLMSQAPISNQQAEVTPTGCLGKQTDQDLSATLLCKLGPGQSEIAEELCQRLQRKERMLQDLLSDRN
KQVLEHEMEIQGLLQSVSTREQESQSMESLLRAKGLEVEQLSTTCQNLQWLKEEMETKFSRWQKEQESIIQQLQTSLHDRNKEVERAIDE
KFSALEEKEKELRQLRLAVRERDHDLERLRDVLSSNEATMQEFRELLQYRDNSDKTLEANEMLLEKLRQRIHDKAVALEELRKALQQLQE
ELQNKSQQLRAWEAEKYNEIRTQEQNIQHLNHSLSHKEQLLQSSEGTSPAQQQVALLDLQSALFCSQLEIQKLQRVVRQKERQLADAKQC
VQFVEAAAHESEQQKEASWKHNQTEELYQVIEGQNDTMAKLREMLHQSQLGQLHILQEKLNEMSYELKCAQESSQKQDGTIQNLKETLKS

--------------------------------------------------------------

>41474_41474_7_KCNK5-PDE4DIP_KCNK5_chr6_39196702_ENST00000359534_PDE4DIP_chr1_144994701_ENST00000369356_length(amino acids)=500AA_BP=0
MVQALMERNSELQALRQYLGGRDSLMSQAPISNQQAEVTPTGCLGKQTDQDLSATLLCKLGPGQSEIAEELCQRLQRKERMLQDLLSDRN
KQVLEHEMEIQGLLQSVSTREQESQSMESLLRAKGLEVEQLSTTCQNLQWLKEEMETKFSRWQKEQESIIQQLQTSLHDRNKEVERAIDE
KFSALEEKEKELRQLRLAVRERDHDLERLRDVLSSNEATMQEFRELLQYRDNSDKTLEANEMLLEKLRQRIHDKAVALEELRKALQQLQE
ELQNKSQQLRAWEAEKYNEIRTQEQNIQHLNHSLSHKEQLLQSSEGTSPAQQQVALLDLQSALFCSQLEIQKLQRVVRQKERQLADAKQC
VQFVEAAAHESEQQKEASWKHNQTEELYQVIEGQNDTMAKLREMLHQSQLGQLHILQEKLNEMSYELKCAQESSQKQDGTIQNLKETLKS

--------------------------------------------------------------

>41474_41474_8_KCNK5-PDE4DIP_KCNK5_chr6_39196702_ENST00000359534_PDE4DIP_chr1_144994701_ENST00000369359_length(amino acids)=2397AA_BP=62
MVDRGPLLTSAIIFYLAIGAAIFEVLEEPHWKEAKKNYYTQKLHLLKEFPCLGQEGLDKILEHLNDLKKENFSLKLRIYFLEERMQQKYE
ASREDIYKRNIELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAARMAA
LVEAEKECNLELSEKLKGVTKNWEDVPGDQVKPDQYTEALAQRDKRIEELNQSLAAQERLVEQLSREKQQLLHLLEEPTSMEVQPMTEEL
LKQQKLNSHETTITQQSVSDSHLAELQEKIQQTEATNKILQEKLNEMSYELKCAQESSQKQDGTIQNLKETLKSRERETEELYQVIEGQN
DTMAKLREMLHQSQLGQLHSSEGTSPAQQQVALLDLQSALFCSQLEIQKLQRVVRQKERQLADAKQCVQFVEAAAHESEQQKEASWKHNQ
ELRKALQQLQEELQNKSQQLRAWEAEKYNEIRTQEQNIQHLNHSLSHKEQLLQEFRELLQYRDNSDKTLEANEMLLEKLRQRIHDKAVAL
ERAIDEKFSALEEKEKELRQLRLAVRERDHDLERLRDVLSSNEATMQSMESLLRAKGLEVEQLSTTCQNLQWLKEEMETKFSRWQKEQES
IIQQLQTSLHDRNKEVEDLSATLLCKLGPGQSEIAEELCQRLQRKERMLQDLLSDRNKQVLEHEMEIQGLLQSVSTREQESQAAAEKLVQ
ALMERNSELQALRQYLGGRDSLMSQAPISNQQAEVTPTGCLGKQTDQGSMQIPSRDDSTSLTAKEDVSIPRSTLGDLDTVAGLEKELSNA
KEELELMAKKERESQMELSALQSMMAVQEEELQVQAADMESLTRNIQIKEDLIKDLQMQLVDPEDIPAMERLTQEVLLLREKVASVESQG
QEISGNRRQQLLLMLEGLVDERSRLNEALQAERQLYSSLVKFHAHPESSERDRTLQVELEGAQVLRSRLEEVLGRSLERLNRLETLAAIG
GAAAGDDTEDTSTEFTDSIEEEAAHHSHQQLVKVALEKSLATVETQNPSFSPPSPMGGDSNRCLQEEMLHLRAEFHQHLEEKRKAEEELK
ELKAQIEEAGFSSVSHIRNTMLSLCLENAELKEQMGEAMSDGWEIEEDKEKGEVMVETVVTKEGLSESSLQAEFRKLQGKLKNAHNIINL
LKEQLVLSSKEGNSKLTPELLVHLTSTIERINTELVGSPGKHQHQEEGNVTVRPFPRPQSLDLGATFTVDAHQLDNQSQPRDPGPQSAFS
LPGSTQHLRSQLSQCKQRYQDLQEKLLLSEATVFAQANELEKYRVMLSESLVKQDSKQIQVDLQDLGYETCGRSENEAEREETTSPECEE
HNSLKEMVLMEGLCSEQGRRGSTLASSSERKPLENQLGKQEEFRVYGKSENILVLRKDIKDLKAQLQNANKVIQNLKSRVRSLSVTSDYS
SSLERPWKLRAVGTLEGSSPHSVPDEDEGWLSDGTGAFYSPGLQAKKDLESLIQRVSQLEAQLPKNGLEEKLAEELRSASWPGKYDSLIQ
DQARELSYLRQKIREGRGICYLITRHAKDTVKSFEDLLRSNDIDYYLGQSFREQLAQGSQLTERLTSKLSTKDHKSEKDQAGLEPLALRL
SRELQEKEKVIEVLQAKLDARSLTPSSSHALSDSHRSPSSTSFLSDELEACSDMDIVSEYTHYEEKKASPSHSDSIHHSSHSAVLSSKPS
STSASQGAKAESNSNPISLPTPQNTPKEANQAHSGFHFHSIPKLASLPQAPLPSAPSSFLPFSPTGPLLLGCCETPVVSLAEAQQELQML
QKQLGESASTVPPASTATLLSNDLEADSSYYLNSAQPHSPPRGTIELGRILEPGYLGSSGKWDVMRPQKGSVSGDLSSGSSVYQLNSKPT
GADLLEEHLGEIRNLRQRLEESICINDRLREQLEHRLTSTARGRGSTSNFYSQGLESIPQLCNENRVLREDNRRLQAQLSHVSREHSQET
ESLREALLSSRSHLQELEKELEHQKVERQQLLEDLREKQQEVLHFREERLSLQENDSRLQHKLVLLQQQCEEKQQLFESLQSELQIYEAL
YGNSKKGLKAYSLDACHQIPLSSDLSHLVAEVRALRGQLEQSIQGNNCLRLQLQQQLESGAGKASLSPSSINQNFPASTDPGNKQLLLQD
SAVSPPVRDVGMNSPALVFPSSASSTPGSETPIINRANGLGLDTSPVMKTPPKLEGDATDGSFANKHGRHVIGHIDDYSALRQQIAEGKL
LVKKIVSLVRSACSFPGLEAQGTEVLGSKGIHELRSSTSALHHALEESASLLTMFWRAALPSTHIPVLPGKVGESTERELLELRTKVSKQ

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>41474_41474_9_KCNK5-PDE4DIP_KCNK5_chr6_39196702_ENST00000359534_PDE4DIP_chr1_144994701_ENST00000530740_length(amino acids)=2346AA_BP=62
MVDRGPLLTSAIIFYLAIGAAIFEVLEEPHWKEAKKNYYTQKLHLLKEFPCLGQEGLDKILEHLNDLKKENFSLKLRIYFLEERMQQKYE
ASREDIYKRNIELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAARMAA
LVEAEKECNLELSEKLKGVTKNWEDVPGDQVKPDQYTEALAQRDKRIEELNQSLAAQERLVEQLSREKQQLLHLLEEPTSMEVQPMTEEL
LKQQKLNSHETTITQQSVSDSHLAELQEKIQQTEATNKILQEKLNEMSYELKCAQESSQKQDGTIQNLKETLKSRERETEELYQVIEGQN
DTMAKLREMLHQSQLGQLHSSEGTSPAQQQVALLDLQSALFCSQLEIQKLQRVVRQKERQLADAKQCVQFVEAAAHESEQQKEASWKHNQ
ELRKALQQLQEELQNKSQQLRAWEAEKYNEIRTQEQNIQHLNHSLSHKEQLLQEFRELLQYRDNSDKTLEANEMLLEKLRQRIHDKAVAL
ERAIDEKFSALEEKEKELRQLRLAVRERDHDLERLRDVLSSNEATMQSMESLLRAKGLEVEQLSTTCQNLQWLKEEMETKFSRWQKEQES
IIQQLQTSLHDRNKEVEDLSATLLCKLGPGQSEIAEELCQRLQRKERMLQDLLSDRNKQVLEHEMEIQGLLQSVSTREQESQAAAEKLVQ
ALMERNSELQALRQYLGGRDSLMSQAPISNQQAEVTPTGCLGKQTDQGSMQIPSRDDSTSLTAKEDVSIPRSTLGDLDTVAGLEKELSNA
KEELELMAKKERESQMELSALQSMMAVQEEELQVQAADMESLTRNIQIKEDLIKDLQMQLVDPEDIPAMERLTQEVLLLREKVASVESQG
QEISGNRRQQLLLMLEGLVDERSRLNEALQAERQLYSSLVKFHAHPESSERDRTLQVELEGAQVLRSRLEEVLGRSLERLNRLETLAAIG
GAAAGDDTEDTSTEFTDSIEEEAAHHSHQQLVKVALEKSLATVETQNPSFSPPSPMGGDSNRCLQEEMLHLRAEFHQHLEEKRKAEEELK
ELKAQIEEAGFSSVSHIRNTMLSLCLENAELKEQMGEAMSDGWEIEEDKEKGEVMVETVVTKEGLSESSLQAEFRKLQGKLKNAHNIINL
LKEQLVLSSKEGNSKLTPELLVHLTSTIERINTELVGSPGKHQHQEEGNVTVRPFPRPQSLDLGATFTVDAHQLDNQSQPRDPGPQSAFS
LPGSTQHLRSQLSQCKQRYQDLQEKLLLSEATVFAQANELEKYRVMLSESLVKQDSKQIQVDLQDLGYETCGRSENEAEREETTSPECEE
HNSLKEMVLMEGLCSEQGRRGSTLASSSERKPLENQLGKQEEFRVYGKSENILVLRKDIKDLKAQLQNANKVIQNLKSRVRSLSVTSDYS
SSLERPWKLRAVGTLEGSSPHSVPDEDEGWLSDGTGAFYSPGLQAKKDLESLIQRVSQLEAQLPKNGLEEKLAEELRSASWPGKYDSLIQ
DQARELSYLRQKIREGRGICYLITRHAKDTVKSFEDLLRSNDIDYYLGQSFREQLAQGSQLTERLTSKLSTKDHKSEKDQAGLEPLALRL
SRELQEKEKVIEVLQAKLDARSLTPSSSHALSDSHRSPSSTSFLSDELEACSDMDIVSEYTHYEEKKASPSHSGFHFHSIPKLASLPQAP
LPSAPSSFLPFSPTGPLLLGCCETPVVSLAEAQQELQMLQKQLGESASTVPPASTATLLSNDLEADSSYYLNSAQPHSPPRGTIELGRIL
EPGYLGSSGKWDVMRPQKGSVSGDLSSGSSVYQLNSKPTGADLLEEHLGEIRNLRQRLEESICINDRLREQLEHRLTSTARGRGSTSNFY
SQGLESIPQLCNENRVLREDNRRLQAQLSHVSREHSQETESLREALLSSRSHLQELEKELEHQKVERQQLLEDLREKQQEVLHFREERLS
LQENDSRLQHKLVLLQQQCEEKQQLFESLQSELQIYEALYGNSKKGLKAYSLDACHQIPLSSDLSHLVAEVRALRGQLEQSIQGNNCLRL
QLQQQLESGAGKASLSPSSINQNFPASTDPGNKQLLLQDSAVSPPVRDVGMNSPALVFPSSASSTPGSETPIINRANGLGLDTSPVMKTP
PKLEGDATDGSFANKHGRHVIGHIDDYSALRQQIAEGKLLVKKIVSLVRSACSFPGLEAQGTEVLGSKGIHELRSSTSALHHALEESASL
LTMFWRAALPSTHIPVLPGKVGESTERELLELRTKVSKQERLLQSTTEHLKNANQQKESMEQFIVSQLTRTHDVLKKARTNLEVKSLRAL

--------------------------------------------------------------

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Fusion Protein Functional Features


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr6:39196702/chr1:144994701)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
KCNK5

O95279

.
FUNCTION: pH-dependent, voltage insensitive, outwardly rectifying potassium channel. Outward rectification is lost at high external K(+) concentrations.FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

* Minus value of BPloci means that the break pointn is located before the CDS.
- Retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneKCNK5chr6:39196702chr1:144994701ENST00000359534-151_762.0500.0Topological domainCytoplasmic
HgeneKCNK5chr6:39196702chr1:144994701ENST00000359534-158_2662.0500.0TransmembraneHelical
TgenePDE4DIPchr6:39196702chr1:144994701ENST000003133822461002_104376.02241.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST000003133822461096_112476.02241.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST000003133822461212_124076.02241.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST000003133822461346_138576.02241.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST000003133822461431_145576.02241.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST00000313382246162_20576.02241.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST000003133822461736_176076.02241.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST000003133822461840_207776.02241.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST000003133822462273_231276.02241.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST00000313382246238_31876.02241.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST00000313382246350_68476.02241.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST00000313382246743_93676.02241.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST000003134310191002_104301133.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST000003134310191096_112401133.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST000003134310191212_124001133.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST000003134310191346_138501133.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST000003134310191431_145501133.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST00000313431019162_20501133.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST000003134310191736_176001133.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST000003134310191840_207701133.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST000003134310192273_231201133.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST00000313431019238_31801133.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST00000313431019350_68401133.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST0000031343101941_13201133.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST00000313431019743_93601133.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST00000369347041002_10430174.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST00000369347041096_11240174.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST00000369347041212_12400174.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST00000369347041346_13850174.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST00000369347041431_14550174.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST0000036934704162_2050174.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST00000369347041736_17600174.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST00000369347041840_20770174.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST00000369347042273_23120174.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST0000036934704238_3180174.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST0000036934704350_6840174.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST000003693470441_1320174.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST0000036934704743_9360174.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST00000369348271002_1043147.0311.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST00000369348271096_1124147.0311.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST00000369348271212_1240147.0311.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST00000369348271346_1385147.0311.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST00000369348271431_1455147.0311.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST0000036934827162_205147.0311.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST00000369348271736_1760147.0311.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST00000369348271840_2077147.0311.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST00000369348272273_2312147.0311.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST0000036934827238_318147.0311.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST0000036934827350_684147.0311.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST0000036934827743_936147.0311.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST000003693490231002_10430970.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST000003693490231096_11240970.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST000003693490231212_12400970.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST000003693490231346_13850970.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST000003693490231431_14550970.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST00000369349023162_2050970.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST000003693490231736_17600970.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST000003693490231840_20770970.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST000003693490232273_23120970.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST00000369349023238_3180970.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST00000369349023350_6840970.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST0000036934902341_1320970.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST00000369349023743_9360970.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST000003693510221002_10430989.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST000003693510221096_11240989.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST000003693510221212_12400989.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST000003693510221346_13850989.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST000003693510221431_14550989.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST00000369351022162_2050989.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST000003693510221736_17600989.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST000003693510221840_20770989.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST000003693510222273_23120989.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST00000369351022238_3180989.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST00000369351022350_6840989.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST0000036935102241_1320989.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST00000369351022743_9360989.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST000003693540441002_104302347.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST000003693540441096_112402347.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST000003693540441212_124002347.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST000003693540441346_138502347.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST000003693540441431_145502347.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST00000369354044162_20502347.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST000003693540441736_176002347.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST000003693540441840_207702347.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST000003693540442273_231202347.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST00000369354044238_31802347.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST00000369354044350_68402347.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST0000036935404441_13202347.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST00000369354044743_93602347.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST000003693560441002_104302363.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST000003693560441096_112402363.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST000003693560441212_124002363.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST000003693560441346_138502363.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST000003693560441431_145502363.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST00000369356044162_20502363.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST000003693560441736_176002363.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST000003693560441840_207702363.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST000003693560442273_231202363.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST00000369356044238_31802363.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST00000369356044350_68402363.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST0000036935604441_13202363.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST00000369356044743_93602363.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST000003133822461551_164276.02241.0DomainOlduvai
TgenePDE4DIPchr6:39196702chr1:144994701ENST000003134310191551_164201133.0DomainOlduvai
TgenePDE4DIPchr6:39196702chr1:144994701ENST00000369347041551_16420174.0DomainOlduvai
TgenePDE4DIPchr6:39196702chr1:144994701ENST00000369348271551_1642147.0311.0DomainOlduvai
TgenePDE4DIPchr6:39196702chr1:144994701ENST000003693490231551_16420970.0DomainOlduvai
TgenePDE4DIPchr6:39196702chr1:144994701ENST000003693510221551_16420989.0DomainOlduvai
TgenePDE4DIPchr6:39196702chr1:144994701ENST000003693540441551_164202347.0DomainOlduvai
TgenePDE4DIPchr6:39196702chr1:144994701ENST000003693560441551_164202363.0DomainOlduvai

- Not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneKCNK5chr6:39196702chr1:144994701ENST00000359534-15190_21562.0500.0IntramembranePore-forming%3B Name%3DPore-forming 2
HgeneKCNK5chr6:39196702chr1:144994701ENST00000359534-1585_11262.0500.0IntramembranePore-forming%3B Name%3DPore-forming 1
HgeneKCNK5chr6:39196702chr1:144994701ENST00000359534-15134_15762.0500.0Topological domainCytoplasmic
HgeneKCNK5chr6:39196702chr1:144994701ENST00000359534-15251_32562.0500.0Topological domainCytoplasmic
HgeneKCNK5chr6:39196702chr1:144994701ENST00000359534-15113_13362.0500.0TransmembraneHelical
HgeneKCNK5chr6:39196702chr1:144994701ENST00000359534-15158_18062.0500.0TransmembraneHelical
HgeneKCNK5chr6:39196702chr1:144994701ENST00000359534-15230_25062.0500.0TransmembraneHelical
TgenePDE4DIPchr6:39196702chr1:144994701ENST0000031338224641_13276.02241.0Coiled coilOntology_term=ECO:0000255
TgenePDE4DIPchr6:39196702chr1:144994701ENST000003693482741_132147.0311.0Coiled coilOntology_term=ECO:0000255


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Fusion Protein-Protein Interaction


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type from validated records (BIOGRID-3.4.160)
GenePPI interactors


check button Protein-protein interactors based on sequence similarity (STRING)
GeneSTRING network
KCNK5
PDE4DIP


check button - Retained interactions in fusion protein (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost interactions due to fusion (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs to KCNK5-PDE4DIP


check button Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDrugSourcePMID

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Related Diseases to KCNK5-PDE4DIP


check button Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDiseaseSourcePMID

check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource