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	Fusion Gene Summary
	Fusion Gene Sample Information
	Fusion ORF Analysis
	Fusion Amino Acid Sequences
	Fusion Protein Functional Features
	Fusion Protein-Protein Interaction
	Related drugs with this fusion protein
	Related disease with this fusion protein

Fusion Protein:KCNMA1-HIVEP3

Fusion Protein Summary

Fusion gene summary

Fusion partner gene information	Fusion gene name: KCNMA1-HIVEP3
	FusionPDB ID: 41489
	FusionGDB2.0 ID: 41489
		Hgene	Tgene
	Gene symbol	KCNMA1	HIVEP3
	Gene ID	3778	59269
	Gene name	potassium calcium-activated channel subfamily M alpha 1	HIVEP zinc finger 3
	Synonyms	BKTM\|CADEDS\|IEG16\|KCa1.1\|LIWAS\|MaxiK\|PNKD3\|SAKCA\|SLO\|SLO-ALPHA\|SLO1\|bA205K10.1\|hSlo\|mSLO1	KBP-1\|KBP1\|KRC\|SHN3\|Schnurri-3\|ZAS3\|ZNF40C
	Cytomap	10q22.3	1p34.2
	Type of gene	protein-coding	protein-coding
	Description	calcium-activated potassium channel subunit alpha-1uncharacterized proteinBK channel alpha subunitBKCA alpha subunitbig potassium channel alpha subunitcalcium-activated potassium channel, subfamily M subunit alpha-1k(VCA)alphamaxi-K channel HSLOpo	transcription factor HIVEP3ZAS family, member 3human immunodeficiency virus type I enhancer binding protein 3kappa-B and V(D)J recombination signal sequences-binding proteinkappa-binding protein 1zinc finger protein ZAS3
	Modification date	20200315	20200313
	UniProtAcc	Q12791	Q5T1R4
Ensembl transtripts involved in fusion gene	ENST ids	ENST00000286627, ENST00000286628, ENST00000354353, ENST00000372440, ENST00000372443, ENST00000404771, ENST00000404857, ENST00000406533, ENST00000480683, ENST00000481070, ENST00000484507,	ENST00000460604, ENST00000247584, ENST00000372583, ENST00000372584, ENST00000429157,
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)	* DoF score	20 X 17 X 10=3400	14 X 14 X 11=2156
	# samples	25	20
	** MAII score	log2(25/3400*10)=-3.76553474636298 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(20/2156*10)=-3.43028527297778 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context (manual curation of fusion genes in FusionPDB)	PubMed: KCNMA1 [Title/Abstract] AND HIVEP3 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)	KCNMA1(78943179)-HIVEP3(41984159), # samples:1
Anticipated loss of major functional domain due to fusion event.	KCNMA1-HIVEP3 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. KCNMA1-HIVEP3 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. KCNMA1-HIVEP3 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. KCNMA1-HIVEP3 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Hgene	KCNMA1	GO:0001666	response to hypoxia	15528406
Hgene	KCNMA1	GO:0006813	potassium ion transport	7573516\|7877450\|11245614\|12388065\|17706472\|18458941
Hgene	KCNMA1	GO:0006970	response to osmotic stress	10840032\|12388065
Hgene	KCNMA1	GO:0030007	cellular potassium ion homeostasis	11245614
Hgene	KCNMA1	GO:0034465	response to carbon monoxide	15528406
Hgene	KCNMA1	GO:0042391	regulation of membrane potential	7877450\|7993625
Hgene	KCNMA1	GO:0045794	negative regulation of cell volume	12388065
Hgene	KCNMA1	GO:0051592	response to calcium ion	12388065\|18458941
Hgene	KCNMA1	GO:0060073	micturition	11641143
Hgene	KCNMA1	GO:0060083	smooth muscle contraction involved in micturition	11641143
Tgene	HIVEP3	GO:0045893	positive regulation of transcription, DNA-templated	15790681

Fusion gene breakpoints across KCNMA1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across HIVEP3 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

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Fusion Gene Sample Information

Fusion gene information from FusionGDB2.0.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	PCPG	TCGA-RW-A688-01A	KCNMA1	chr10	78943179	-	HIVEP3	chr1	41984159	-

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Fusion ORF Analysis

Fusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000404771	KCNMA1	chr10	78943179	-	ENST00000372583	HIVEP3	chr1	41984159	-	6848	924	62	2761	899
ENST00000404771	KCNMA1	chr10	78943179	-	ENST00000372584	HIVEP3	chr1	41984159	-	6845	924	62	2758	898
ENST00000404771	KCNMA1	chr10	78943179	-	ENST00000247584	HIVEP3	chr1	41984159	-	3200	924	62	2761	899
ENST00000404771	KCNMA1	chr10	78943179	-	ENST00000429157	HIVEP3	chr1	41984159	-	2759	924	62	2758	899
ENST00000372440	KCNMA1	chr10	78943179	-	ENST00000372583	HIVEP3	chr1	41984159	-	7083	1159	297	2996	899
ENST00000372440	KCNMA1	chr10	78943179	-	ENST00000372584	HIVEP3	chr1	41984159	-	7080	1159	297	2993	898
ENST00000372440	KCNMA1	chr10	78943179	-	ENST00000247584	HIVEP3	chr1	41984159	-	3435	1159	297	2996	899
ENST00000372440	KCNMA1	chr10	78943179	-	ENST00000429157	HIVEP3	chr1	41984159	-	2994	1159	297	2993	898
ENST00000372443	KCNMA1	chr10	78943179	-	ENST00000372583	HIVEP3	chr1	41984159	-	7459	1535	673	3372	899
ENST00000372443	KCNMA1	chr10	78943179	-	ENST00000372584	HIVEP3	chr1	41984159	-	7456	1535	673	3369	898
ENST00000372443	KCNMA1	chr10	78943179	-	ENST00000247584	HIVEP3	chr1	41984159	-	3811	1535	673	3372	899
ENST00000372443	KCNMA1	chr10	78943179	-	ENST00000429157	HIVEP3	chr1	41984159	-	3370	1535	673	3369	899
ENST00000286628	KCNMA1	chr10	78943179	-	ENST00000372583	HIVEP3	chr1	41984159	-	6732	808	0	2645	881
ENST00000286628	KCNMA1	chr10	78943179	-	ENST00000372584	HIVEP3	chr1	41984159	-	6729	808	0	2642	880
ENST00000286628	KCNMA1	chr10	78943179	-	ENST00000247584	HIVEP3	chr1	41984159	-	3084	808	0	2645	881
ENST00000286628	KCNMA1	chr10	78943179	-	ENST00000429157	HIVEP3	chr1	41984159	-	2643	808	0	2642	880
ENST00000286627	KCNMA1	chr10	78943179	-	ENST00000372583	HIVEP3	chr1	41984159	-	7685	1761	899	3598	899
ENST00000286627	KCNMA1	chr10	78943179	-	ENST00000372584	HIVEP3	chr1	41984159	-	7682	1761	899	3595	898
ENST00000286627	KCNMA1	chr10	78943179	-	ENST00000247584	HIVEP3	chr1	41984159	-	4037	1761	899	3598	899
ENST00000286627	KCNMA1	chr10	78943179	-	ENST00000429157	HIVEP3	chr1	41984159	-	3596	1761	899	3595	899
ENST00000354353	KCNMA1	chr10	78943179	-	ENST00000372583	HIVEP3	chr1	41984159	-	6732	808	0	2645	881
ENST00000354353	KCNMA1	chr10	78943179	-	ENST00000372584	HIVEP3	chr1	41984159	-	6729	808	0	2642	880
ENST00000354353	KCNMA1	chr10	78943179	-	ENST00000247584	HIVEP3	chr1	41984159	-	3084	808	0	2645	881
ENST00000354353	KCNMA1	chr10	78943179	-	ENST00000429157	HIVEP3	chr1	41984159	-	2643	808	0	2642	880
ENST00000404857	KCNMA1	chr10	78943179	-	ENST00000372583	HIVEP3	chr1	41984159	-	6732	808	0	2645	881
ENST00000404857	KCNMA1	chr10	78943179	-	ENST00000372584	HIVEP3	chr1	41984159	-	6729	808	0	2642	880
ENST00000404857	KCNMA1	chr10	78943179	-	ENST00000247584	HIVEP3	chr1	41984159	-	3084	808	0	2645	881
ENST00000404857	KCNMA1	chr10	78943179	-	ENST00000429157	HIVEP3	chr1	41984159	-	2643	808	0	2642	880
ENST00000406533	KCNMA1	chr10	78943179	-	ENST00000372583	HIVEP3	chr1	41984159	-	6732	808	0	2645	881
ENST00000406533	KCNMA1	chr10	78943179	-	ENST00000372584	HIVEP3	chr1	41984159	-	6729	808	0	2642	880
ENST00000406533	KCNMA1	chr10	78943179	-	ENST00000247584	HIVEP3	chr1	41984159	-	3084	808	0	2645	881
ENST00000406533	KCNMA1	chr10	78943179	-	ENST00000429157	HIVEP3	chr1	41984159	-	2643	808	0	2642	880

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000404771	ENST00000372583	KCNMA1	chr10	78943179	-	HIVEP3	chr1	41984159	-	0.009220742	0.9907793
ENST00000404771	ENST00000372584	KCNMA1	chr10	78943179	-	HIVEP3	chr1	41984159	-	0.008976448	0.99102354
ENST00000404771	ENST00000247584	KCNMA1	chr10	78943179	-	HIVEP3	chr1	41984159	-	0.01821495	0.98178506
ENST00000404771	ENST00000429157	KCNMA1	chr10	78943179	-	HIVEP3	chr1	41984159	-	0.024188852	0.9758111
ENST00000372440	ENST00000372583	KCNMA1	chr10	78943179	-	HIVEP3	chr1	41984159	-	0.00947801	0.990522
ENST00000372440	ENST00000372584	KCNMA1	chr10	78943179	-	HIVEP3	chr1	41984159	-	0.009232171	0.9907678
ENST00000372440	ENST00000247584	KCNMA1	chr10	78943179	-	HIVEP3	chr1	41984159	-	0.017659646	0.98234034
ENST00000372440	ENST00000429157	KCNMA1	chr10	78943179	-	HIVEP3	chr1	41984159	-	0.022115445	0.9778846
ENST00000372443	ENST00000372583	KCNMA1	chr10	78943179	-	HIVEP3	chr1	41984159	-	0.009005914	0.99099404
ENST00000372443	ENST00000372584	KCNMA1	chr10	78943179	-	HIVEP3	chr1	41984159	-	0.008782795	0.99121726
ENST00000372443	ENST00000247584	KCNMA1	chr10	78943179	-	HIVEP3	chr1	41984159	-	0.016046146	0.98395383
ENST00000372443	ENST00000429157	KCNMA1	chr10	78943179	-	HIVEP3	chr1	41984159	-	0.018963553	0.9810364
ENST00000286628	ENST00000372583	KCNMA1	chr10	78943179	-	HIVEP3	chr1	41984159	-	0.009255709	0.9907443
ENST00000286628	ENST00000372584	KCNMA1	chr10	78943179	-	HIVEP3	chr1	41984159	-	0.009021007	0.99097896
ENST00000286628	ENST00000247584	KCNMA1	chr10	78943179	-	HIVEP3	chr1	41984159	-	0.016552385	0.9834477
ENST00000286628	ENST00000429157	KCNMA1	chr10	78943179	-	HIVEP3	chr1	41984159	-	0.023442773	0.9765572
ENST00000286627	ENST00000372583	KCNMA1	chr10	78943179	-	HIVEP3	chr1	41984159	-	0.009238733	0.9907612
ENST00000286627	ENST00000372584	KCNMA1	chr10	78943179	-	HIVEP3	chr1	41984159	-	0.009036115	0.9909638
ENST00000286627	ENST00000247584	KCNMA1	chr10	78943179	-	HIVEP3	chr1	41984159	-	0.016346222	0.9836537
ENST00000286627	ENST00000429157	KCNMA1	chr10	78943179	-	HIVEP3	chr1	41984159	-	0.019363888	0.98063606
ENST00000354353	ENST00000372583	KCNMA1	chr10	78943179	-	HIVEP3	chr1	41984159	-	0.009255709	0.9907443
ENST00000354353	ENST00000372584	KCNMA1	chr10	78943179	-	HIVEP3	chr1	41984159	-	0.009021007	0.99097896
ENST00000354353	ENST00000247584	KCNMA1	chr10	78943179	-	HIVEP3	chr1	41984159	-	0.016552385	0.9834477
ENST00000354353	ENST00000429157	KCNMA1	chr10	78943179	-	HIVEP3	chr1	41984159	-	0.023442773	0.9765572
ENST00000404857	ENST00000372583	KCNMA1	chr10	78943179	-	HIVEP3	chr1	41984159	-	0.009255709	0.9907443
ENST00000404857	ENST00000372584	KCNMA1	chr10	78943179	-	HIVEP3	chr1	41984159	-	0.009021007	0.99097896
ENST00000404857	ENST00000247584	KCNMA1	chr10	78943179	-	HIVEP3	chr1	41984159	-	0.016552385	0.9834477
ENST00000404857	ENST00000429157	KCNMA1	chr10	78943179	-	HIVEP3	chr1	41984159	-	0.023442773	0.9765572
ENST00000406533	ENST00000372583	KCNMA1	chr10	78943179	-	HIVEP3	chr1	41984159	-	0.009255709	0.9907443
ENST00000406533	ENST00000372584	KCNMA1	chr10	78943179	-	HIVEP3	chr1	41984159	-	0.009021007	0.99097896
ENST00000406533	ENST00000247584	KCNMA1	chr10	78943179	-	HIVEP3	chr1	41984159	-	0.016552385	0.9834477
ENST00000406533	ENST00000429157	KCNMA1	chr10	78943179	-	HIVEP3	chr1	41984159	-	0.023442773	0.9765572

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Fusion Amino Acid Sequences

For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

>41489_41489_1_KCNMA1-HIVEP3_KCNMA1_chr10_78943179_ENST00000286627_HIVEP3_chr1_41984159_ENST00000247584_length(amino acids)=899AA_BP=286
MAAGGAPPSPCAGCPLLAMANGGGGGGGSSGGGGGGGGSSLRMSSNIHANHLSLDASSSSSSSSSSSSSSSSSSSSSSVHEPKMDALIIP
VTMEVPCDSRGQRMWWAFLASSMVTFFGGLFIILLWRTLKYLWTVCCHCGGKTKEAQKINNGSSQADGTLKPVDEKEEAVAAEVGWMTSV
KDWAGVMISAQTLTGRVLVVLVFALSIGALVIYFIDSSNPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDF
FTVPPVFVSVYLNRSWLGNLTKHMKSKAHSKKCQETGVLEELEAEEGTSDDLFQDSEGREGSEAVEEHQFSDLEDSDSDSDLDEDEDEDE
EESQDELSRPSSEAPPPGPPHALRADSSPILGPQPPDAPASGTEATRGSSVSEAERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSA
LSYKPVSPRRPWSPSKEAGSRPPLARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLTLCPLGRELAP
RAHVLSKLEGTTDPGLPRYSPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAGEHGPGLGLDPRVLFPPAPLPHKLLSRSPETCASPWQK
AESRSPSCSPGPAHPLSSRPFSALHDFHGHILARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQMVQARPGAHPTLLPGPTAAWVSGFSG
GGSDLTGAREAQERGRWSPTESSSASVSPVAKVSKFTLSSELEGGDYPKERERTGGGPGRPPDWTPHGTGAPAEPTPTHSPCTPPDTLPR

--------------------------------------------------------------

>41489_41489_2_KCNMA1-HIVEP3_KCNMA1_chr10_78943179_ENST00000286627_HIVEP3_chr1_41984159_ENST00000372583_length(amino acids)=899AA_BP=286
MAAGGAPPSPCAGCPLLAMANGGGGGGGSSGGGGGGGGSSLRMSSNIHANHLSLDASSSSSSSSSSSSSSSSSSSSSSVHEPKMDALIIP
VTMEVPCDSRGQRMWWAFLASSMVTFFGGLFIILLWRTLKYLWTVCCHCGGKTKEAQKINNGSSQADGTLKPVDEKEEAVAAEVGWMTSV
KDWAGVMISAQTLTGRVLVVLVFALSIGALVIYFIDSSNPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDF
FTVPPVFVSVYLNRSWLGNLTKHMKSKAHSKKCQETGVLEELEAEEGTSDDLFQDSEGREGSEAVEEHQFSDLEDSDSDSDLDEDEDEDE
EESQDELSRPSSEAPPPGPPHALRADSSPILGPQPPDAPASGTEATRGSSVSEAERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSA
LSYKPVSPRRPWSPSKEAGSRPPLARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLTLCPLGRELAP
RAHVLSKLEGTTDPGLPRYSPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAGEHGPGLGLDPRVLFPPAPLPHKLLSRSPETCASPWQK
AESRSPSCSPGPAHPLSSRPFSALHDFHGHILARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQMVQARPGAHPTLLPGPTAAWVSGFSG
GGSDLTGAREAQERGRWSPTESSSASVSPVAKVSKFTLSSELEGGDYPKERERTGGGPGRPPDWTPHGTGAPAEPTPTHSPCTPPDTLPR

--------------------------------------------------------------

>41489_41489_3_KCNMA1-HIVEP3_KCNMA1_chr10_78943179_ENST00000286627_HIVEP3_chr1_41984159_ENST00000372584_length(amino acids)=898AA_BP=286
MAAGGAPPSPCAGCPLLAMANGGGGGGGSSGGGGGGGGSSLRMSSNIHANHLSLDASSSSSSSSSSSSSSSSSSSSSSVHEPKMDALIIP
VTMEVPCDSRGQRMWWAFLASSMVTFFGGLFIILLWRTLKYLWTVCCHCGGKTKEAQKINNGSSQADGTLKPVDEKEEAVAAEVGWMTSV
KDWAGVMISAQTLTGRVLVVLVFALSIGALVIYFIDSSNPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDF
FTVPPVFVSVYLNRSWLGNLTKHMKSKAHSKKCQETGVLEELEAEEGTSDDLFQDSEGREGSEAVEEHQFSDLEDSDSDSDLDEDEDEDE
EESQDELSRPSSEAPPPGPPHALRADSSPILGPQPPDAPASGTEATRGSSVSEAERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSA
LSYKPVSPRRPWSPSKEAGSRPPLARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLTLCPLGRELAP
RAHVLSKLEGTTDPGLPRYSPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAGEHGPGLGLDPRVLFPPAPLPHKLLSRSPETCASPWKA
ESRSPSCSPGPAHPLSSRPFSALHDFHGHILARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQMVQARPGAHPTLLPGPTAAWVSGFSGG
GSDLTGAREAQERGRWSPTESSSASVSPVAKVSKFTLSSELEGGDYPKERERTGGGPGRPPDWTPHGTGAPAEPTPTHSPCTPPDTLPRP

--------------------------------------------------------------

>41489_41489_4_KCNMA1-HIVEP3_KCNMA1_chr10_78943179_ENST00000286627_HIVEP3_chr1_41984159_ENST00000429157_length(amino acids)=899AA_BP=286
MAAGGAPPSPCAGCPLLAMANGGGGGGGSSGGGGGGGGSSLRMSSNIHANHLSLDASSSSSSSSSSSSSSSSSSSSSSVHEPKMDALIIP
VTMEVPCDSRGQRMWWAFLASSMVTFFGGLFIILLWRTLKYLWTVCCHCGGKTKEAQKINNGSSQADGTLKPVDEKEEAVAAEVGWMTSV
KDWAGVMISAQTLTGRVLVVLVFALSIGALVIYFIDSSNPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDF
FTVPPVFVSVYLNRSWLGNLTKHMKSKAHSKKCQETGVLEELEAEEGTSDDLFQDSEGREGSEAVEEHQFSDLEDSDSDSDLDEDEDEDE
EESQDELSRPSSEAPPPGPPHALRADSSPILGPQPPDAPASGTEATRGSSVSEAERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSA
LSYKPVSPRRPWSPSKEAGSRPPLARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLTLCPLGRELAP
RAHVLSKLEGTTDPGLPRYSPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAGEHGPGLGLDPRVLFPPAPLPHKLLSRSPETCASPWKA
ESRSPSCSPGPAHPLSSRPFSALHDFHGHILARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQMVQARPGAHPTLLPGPTAAWVSGFSGG
GSDLTGAREAQERGRWSPTESSSASVSPVAKVSKFTLSSELEGGDYPKERERTGGGPGRPPDWTPHGTGAPAEPTPTHSPCTPPDTLPRP

--------------------------------------------------------------

>41489_41489_5_KCNMA1-HIVEP3_KCNMA1_chr10_78943179_ENST00000286628_HIVEP3_chr1_41984159_ENST00000247584_length(amino acids)=881AA_BP=268
MANGGGGGGGSSGGGGGGGGSSLRMSSNIHANHLSLDASSSSSSSSSSSSSSSSSSSSSSVHEPKMDALIIPVTMEVPCDSRGQRMWWAF
LASSMVTFFGGLFIILLWRTLKYLWTVCCHCGGKTKEAQKINNGSSQADGTLKPVDEKEEAVAAEVGWMTSVKDWAGVMISAQTLTGRVL
VVLVFALSIGALVIYFIDSSNPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLG
NLTKHMKSKAHSKKCQETGVLEELEAEEGTSDDLFQDSEGREGSEAVEEHQFSDLEDSDSDSDLDEDEDEDEEESQDELSRPSSEAPPPG
PPHALRADSSPILGPQPPDAPASGTEATRGSSVSEAERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSALSYKPVSPRRPWSPSKEA
GSRPPLARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLTLCPLGRELAPRAHVLSKLEGTTDPGLPR
YSPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAGEHGPGLGLDPRVLFPPAPLPHKLLSRSPETCASPWQKAESRSPSCSPGPAHPLSS
RPFSALHDFHGHILARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQMVQARPGAHPTLLPGPTAAWVSGFSGGGSDLTGAREAQERGRWS
PTESSSASVSPVAKVSKFTLSSELEGGDYPKERERTGGGPGRPPDWTPHGTGAPAEPTPTHSPCTPPDTLPRPPQGRRAAQSWSPRLESP

--------------------------------------------------------------

>41489_41489_6_KCNMA1-HIVEP3_KCNMA1_chr10_78943179_ENST00000286628_HIVEP3_chr1_41984159_ENST00000372583_length(amino acids)=881AA_BP=268
MANGGGGGGGSSGGGGGGGGSSLRMSSNIHANHLSLDASSSSSSSSSSSSSSSSSSSSSSVHEPKMDALIIPVTMEVPCDSRGQRMWWAF
LASSMVTFFGGLFIILLWRTLKYLWTVCCHCGGKTKEAQKINNGSSQADGTLKPVDEKEEAVAAEVGWMTSVKDWAGVMISAQTLTGRVL
VVLVFALSIGALVIYFIDSSNPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLG
NLTKHMKSKAHSKKCQETGVLEELEAEEGTSDDLFQDSEGREGSEAVEEHQFSDLEDSDSDSDLDEDEDEDEEESQDELSRPSSEAPPPG
PPHALRADSSPILGPQPPDAPASGTEATRGSSVSEAERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSALSYKPVSPRRPWSPSKEA
GSRPPLARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLTLCPLGRELAPRAHVLSKLEGTTDPGLPR
YSPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAGEHGPGLGLDPRVLFPPAPLPHKLLSRSPETCASPWQKAESRSPSCSPGPAHPLSS
RPFSALHDFHGHILARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQMVQARPGAHPTLLPGPTAAWVSGFSGGGSDLTGAREAQERGRWS
PTESSSASVSPVAKVSKFTLSSELEGGDYPKERERTGGGPGRPPDWTPHGTGAPAEPTPTHSPCTPPDTLPRPPQGRRAAQSWSPRLESP

--------------------------------------------------------------

>41489_41489_7_KCNMA1-HIVEP3_KCNMA1_chr10_78943179_ENST00000286628_HIVEP3_chr1_41984159_ENST00000372584_length(amino acids)=880AA_BP=268
MANGGGGGGGSSGGGGGGGGSSLRMSSNIHANHLSLDASSSSSSSSSSSSSSSSSSSSSSVHEPKMDALIIPVTMEVPCDSRGQRMWWAF
LASSMVTFFGGLFIILLWRTLKYLWTVCCHCGGKTKEAQKINNGSSQADGTLKPVDEKEEAVAAEVGWMTSVKDWAGVMISAQTLTGRVL
VVLVFALSIGALVIYFIDSSNPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLG
NLTKHMKSKAHSKKCQETGVLEELEAEEGTSDDLFQDSEGREGSEAVEEHQFSDLEDSDSDSDLDEDEDEDEEESQDELSRPSSEAPPPG
PPHALRADSSPILGPQPPDAPASGTEATRGSSVSEAERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSALSYKPVSPRRPWSPSKEA
GSRPPLARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLTLCPLGRELAPRAHVLSKLEGTTDPGLPR
YSPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAGEHGPGLGLDPRVLFPPAPLPHKLLSRSPETCASPWKAESRSPSCSPGPAHPLSSR
PFSALHDFHGHILARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQMVQARPGAHPTLLPGPTAAWVSGFSGGGSDLTGAREAQERGRWSP
TESSSASVSPVAKVSKFTLSSELEGGDYPKERERTGGGPGRPPDWTPHGTGAPAEPTPTHSPCTPPDTLPRPPQGRRAAQSWSPRLESPR

--------------------------------------------------------------

>41489_41489_8_KCNMA1-HIVEP3_KCNMA1_chr10_78943179_ENST00000286628_HIVEP3_chr1_41984159_ENST00000429157_length(amino acids)=880AA_BP=268
MANGGGGGGGSSGGGGGGGGSSLRMSSNIHANHLSLDASSSSSSSSSSSSSSSSSSSSSSVHEPKMDALIIPVTMEVPCDSRGQRMWWAF
LASSMVTFFGGLFIILLWRTLKYLWTVCCHCGGKTKEAQKINNGSSQADGTLKPVDEKEEAVAAEVGWMTSVKDWAGVMISAQTLTGRVL
VVLVFALSIGALVIYFIDSSNPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLG
NLTKHMKSKAHSKKCQETGVLEELEAEEGTSDDLFQDSEGREGSEAVEEHQFSDLEDSDSDSDLDEDEDEDEEESQDELSRPSSEAPPPG
PPHALRADSSPILGPQPPDAPASGTEATRGSSVSEAERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSALSYKPVSPRRPWSPSKEA
GSRPPLARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLTLCPLGRELAPRAHVLSKLEGTTDPGLPR
YSPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAGEHGPGLGLDPRVLFPPAPLPHKLLSRSPETCASPWKAESRSPSCSPGPAHPLSSR
PFSALHDFHGHILARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQMVQARPGAHPTLLPGPTAAWVSGFSGGGSDLTGAREAQERGRWSP
TESSSASVSPVAKVSKFTLSSELEGGDYPKERERTGGGPGRPPDWTPHGTGAPAEPTPTHSPCTPPDTLPRPPQGRRAAQSWSPRLESPR

--------------------------------------------------------------

>41489_41489_9_KCNMA1-HIVEP3_KCNMA1_chr10_78943179_ENST00000354353_HIVEP3_chr1_41984159_ENST00000247584_length(amino acids)=881AA_BP=268
MANGGGGGGGSSGGGGGGGGSSLRMSSNIHANHLSLDASSSSSSSSSSSSSSSSSSSSSSVHEPKMDALIIPVTMEVPCDSRGQRMWWAF
LASSMVTFFGGLFIILLWRTLKYLWTVCCHCGGKTKEAQKINNGSSQADGTLKPVDEKEEAVAAEVGWMTSVKDWAGVMISAQTLTGRVL
VVLVFALSIGALVIYFIDSSNPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLG
NLTKHMKSKAHSKKCQETGVLEELEAEEGTSDDLFQDSEGREGSEAVEEHQFSDLEDSDSDSDLDEDEDEDEEESQDELSRPSSEAPPPG
PPHALRADSSPILGPQPPDAPASGTEATRGSSVSEAERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSALSYKPVSPRRPWSPSKEA
GSRPPLARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLTLCPLGRELAPRAHVLSKLEGTTDPGLPR
YSPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAGEHGPGLGLDPRVLFPPAPLPHKLLSRSPETCASPWQKAESRSPSCSPGPAHPLSS
RPFSALHDFHGHILARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQMVQARPGAHPTLLPGPTAAWVSGFSGGGSDLTGAREAQERGRWS
PTESSSASVSPVAKVSKFTLSSELEGGDYPKERERTGGGPGRPPDWTPHGTGAPAEPTPTHSPCTPPDTLPRPPQGRRAAQSWSPRLESP

--------------------------------------------------------------

>41489_41489_10_KCNMA1-HIVEP3_KCNMA1_chr10_78943179_ENST00000354353_HIVEP3_chr1_41984159_ENST00000372583_length(amino acids)=881AA_BP=268
MANGGGGGGGSSGGGGGGGGSSLRMSSNIHANHLSLDASSSSSSSSSSSSSSSSSSSSSSVHEPKMDALIIPVTMEVPCDSRGQRMWWAF
LASSMVTFFGGLFIILLWRTLKYLWTVCCHCGGKTKEAQKINNGSSQADGTLKPVDEKEEAVAAEVGWMTSVKDWAGVMISAQTLTGRVL
VVLVFALSIGALVIYFIDSSNPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLG
NLTKHMKSKAHSKKCQETGVLEELEAEEGTSDDLFQDSEGREGSEAVEEHQFSDLEDSDSDSDLDEDEDEDEEESQDELSRPSSEAPPPG
PPHALRADSSPILGPQPPDAPASGTEATRGSSVSEAERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSALSYKPVSPRRPWSPSKEA
GSRPPLARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLTLCPLGRELAPRAHVLSKLEGTTDPGLPR
YSPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAGEHGPGLGLDPRVLFPPAPLPHKLLSRSPETCASPWQKAESRSPSCSPGPAHPLSS
RPFSALHDFHGHILARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQMVQARPGAHPTLLPGPTAAWVSGFSGGGSDLTGAREAQERGRWS
PTESSSASVSPVAKVSKFTLSSELEGGDYPKERERTGGGPGRPPDWTPHGTGAPAEPTPTHSPCTPPDTLPRPPQGRRAAQSWSPRLESP

--------------------------------------------------------------

>41489_41489_11_KCNMA1-HIVEP3_KCNMA1_chr10_78943179_ENST00000354353_HIVEP3_chr1_41984159_ENST00000372584_length(amino acids)=880AA_BP=268
MANGGGGGGGSSGGGGGGGGSSLRMSSNIHANHLSLDASSSSSSSSSSSSSSSSSSSSSSVHEPKMDALIIPVTMEVPCDSRGQRMWWAF
LASSMVTFFGGLFIILLWRTLKYLWTVCCHCGGKTKEAQKINNGSSQADGTLKPVDEKEEAVAAEVGWMTSVKDWAGVMISAQTLTGRVL
VVLVFALSIGALVIYFIDSSNPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLG
NLTKHMKSKAHSKKCQETGVLEELEAEEGTSDDLFQDSEGREGSEAVEEHQFSDLEDSDSDSDLDEDEDEDEEESQDELSRPSSEAPPPG
PPHALRADSSPILGPQPPDAPASGTEATRGSSVSEAERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSALSYKPVSPRRPWSPSKEA
GSRPPLARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLTLCPLGRELAPRAHVLSKLEGTTDPGLPR
YSPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAGEHGPGLGLDPRVLFPPAPLPHKLLSRSPETCASPWKAESRSPSCSPGPAHPLSSR
PFSALHDFHGHILARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQMVQARPGAHPTLLPGPTAAWVSGFSGGGSDLTGAREAQERGRWSP
TESSSASVSPVAKVSKFTLSSELEGGDYPKERERTGGGPGRPPDWTPHGTGAPAEPTPTHSPCTPPDTLPRPPQGRRAAQSWSPRLESPR

--------------------------------------------------------------

>41489_41489_12_KCNMA1-HIVEP3_KCNMA1_chr10_78943179_ENST00000354353_HIVEP3_chr1_41984159_ENST00000429157_length(amino acids)=880AA_BP=268
MANGGGGGGGSSGGGGGGGGSSLRMSSNIHANHLSLDASSSSSSSSSSSSSSSSSSSSSSVHEPKMDALIIPVTMEVPCDSRGQRMWWAF
LASSMVTFFGGLFIILLWRTLKYLWTVCCHCGGKTKEAQKINNGSSQADGTLKPVDEKEEAVAAEVGWMTSVKDWAGVMISAQTLTGRVL
VVLVFALSIGALVIYFIDSSNPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLG
NLTKHMKSKAHSKKCQETGVLEELEAEEGTSDDLFQDSEGREGSEAVEEHQFSDLEDSDSDSDLDEDEDEDEEESQDELSRPSSEAPPPG
PPHALRADSSPILGPQPPDAPASGTEATRGSSVSEAERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSALSYKPVSPRRPWSPSKEA
GSRPPLARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLTLCPLGRELAPRAHVLSKLEGTTDPGLPR
YSPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAGEHGPGLGLDPRVLFPPAPLPHKLLSRSPETCASPWKAESRSPSCSPGPAHPLSSR
PFSALHDFHGHILARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQMVQARPGAHPTLLPGPTAAWVSGFSGGGSDLTGAREAQERGRWSP
TESSSASVSPVAKVSKFTLSSELEGGDYPKERERTGGGPGRPPDWTPHGTGAPAEPTPTHSPCTPPDTLPRPPQGRRAAQSWSPRLESPR

--------------------------------------------------------------

>41489_41489_13_KCNMA1-HIVEP3_KCNMA1_chr10_78943179_ENST00000372440_HIVEP3_chr1_41984159_ENST00000247584_length(amino acids)=899AA_BP=286
MAAGGAPPSPCAGCPLLAMANGGGGGGGSSGGGGGGGGSSLRMSSNIHANHLSLDASSSSSSSSSSSSSSSSSSSSSSVHEPKMDALIIP
VTMEVPCDSRGQRMWWAFLASSMVTFFGGLFIILLWRTLKYLWTVCCHCGGKTKEAQKINNGSSQADGTLKPVDEKEEAVAAEVGWMTSV
KDWAGVMISAQTLTGRVLVVLVFALSIGALVIYFIDSSNPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDF
FTVPPVFVSVYLNRSWLGNLTKHMKSKAHSKKCQETGVLEELEAEEGTSDDLFQDSEGREGSEAVEEHQFSDLEDSDSDSDLDEDEDEDE
EESQDELSRPSSEAPPPGPPHALRADSSPILGPQPPDAPASGTEATRGSSVSEAERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSA
LSYKPVSPRRPWSPSKEAGSRPPLARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLTLCPLGRELAP
RAHVLSKLEGTTDPGLPRYSPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAGEHGPGLGLDPRVLFPPAPLPHKLLSRSPETCASPWQK
AESRSPSCSPGPAHPLSSRPFSALHDFHGHILARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQMVQARPGAHPTLLPGPTAAWVSGFSG
GGSDLTGAREAQERGRWSPTESSSASVSPVAKVSKFTLSSELEGGDYPKERERTGGGPGRPPDWTPHGTGAPAEPTPTHSPCTPPDTLPR

--------------------------------------------------------------

>41489_41489_14_KCNMA1-HIVEP3_KCNMA1_chr10_78943179_ENST00000372440_HIVEP3_chr1_41984159_ENST00000372583_length(amino acids)=899AA_BP=286
MAAGGAPPSPCAGCPLLAMANGGGGGGGSSGGGGGGGGSSLRMSSNIHANHLSLDASSSSSSSSSSSSSSSSSSSSSSVHEPKMDALIIP
VTMEVPCDSRGQRMWWAFLASSMVTFFGGLFIILLWRTLKYLWTVCCHCGGKTKEAQKINNGSSQADGTLKPVDEKEEAVAAEVGWMTSV
KDWAGVMISAQTLTGRVLVVLVFALSIGALVIYFIDSSNPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDF
FTVPPVFVSVYLNRSWLGNLTKHMKSKAHSKKCQETGVLEELEAEEGTSDDLFQDSEGREGSEAVEEHQFSDLEDSDSDSDLDEDEDEDE
EESQDELSRPSSEAPPPGPPHALRADSSPILGPQPPDAPASGTEATRGSSVSEAERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSA
LSYKPVSPRRPWSPSKEAGSRPPLARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLTLCPLGRELAP
RAHVLSKLEGTTDPGLPRYSPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAGEHGPGLGLDPRVLFPPAPLPHKLLSRSPETCASPWQK
AESRSPSCSPGPAHPLSSRPFSALHDFHGHILARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQMVQARPGAHPTLLPGPTAAWVSGFSG
GGSDLTGAREAQERGRWSPTESSSASVSPVAKVSKFTLSSELEGGDYPKERERTGGGPGRPPDWTPHGTGAPAEPTPTHSPCTPPDTLPR

--------------------------------------------------------------

>41489_41489_15_KCNMA1-HIVEP3_KCNMA1_chr10_78943179_ENST00000372440_HIVEP3_chr1_41984159_ENST00000372584_length(amino acids)=898AA_BP=286
MAAGGAPPSPCAGCPLLAMANGGGGGGGSSGGGGGGGGSSLRMSSNIHANHLSLDASSSSSSSSSSSSSSSSSSSSSSVHEPKMDALIIP
VTMEVPCDSRGQRMWWAFLASSMVTFFGGLFIILLWRTLKYLWTVCCHCGGKTKEAQKINNGSSQADGTLKPVDEKEEAVAAEVGWMTSV
KDWAGVMISAQTLTGRVLVVLVFALSIGALVIYFIDSSNPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDF
FTVPPVFVSVYLNRSWLGNLTKHMKSKAHSKKCQETGVLEELEAEEGTSDDLFQDSEGREGSEAVEEHQFSDLEDSDSDSDLDEDEDEDE
EESQDELSRPSSEAPPPGPPHALRADSSPILGPQPPDAPASGTEATRGSSVSEAERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSA
LSYKPVSPRRPWSPSKEAGSRPPLARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLTLCPLGRELAP
RAHVLSKLEGTTDPGLPRYSPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAGEHGPGLGLDPRVLFPPAPLPHKLLSRSPETCASPWKA
ESRSPSCSPGPAHPLSSRPFSALHDFHGHILARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQMVQARPGAHPTLLPGPTAAWVSGFSGG
GSDLTGAREAQERGRWSPTESSSASVSPVAKVSKFTLSSELEGGDYPKERERTGGGPGRPPDWTPHGTGAPAEPTPTHSPCTPPDTLPRP

--------------------------------------------------------------

>41489_41489_16_KCNMA1-HIVEP3_KCNMA1_chr10_78943179_ENST00000372440_HIVEP3_chr1_41984159_ENST00000429157_length(amino acids)=898AA_BP=286
MAAGGAPPSPCAGCPLLAMANGGGGGGGSSGGGGGGGGSSLRMSSNIHANHLSLDASSSSSSSSSSSSSSSSSSSSSSVHEPKMDALIIP
VTMEVPCDSRGQRMWWAFLASSMVTFFGGLFIILLWRTLKYLWTVCCHCGGKTKEAQKINNGSSQADGTLKPVDEKEEAVAAEVGWMTSV
KDWAGVMISAQTLTGRVLVVLVFALSIGALVIYFIDSSNPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDF
FTVPPVFVSVYLNRSWLGNLTKHMKSKAHSKKCQETGVLEELEAEEGTSDDLFQDSEGREGSEAVEEHQFSDLEDSDSDSDLDEDEDEDE
EESQDELSRPSSEAPPPGPPHALRADSSPILGPQPPDAPASGTEATRGSSVSEAERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSA
LSYKPVSPRRPWSPSKEAGSRPPLARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLTLCPLGRELAP
RAHVLSKLEGTTDPGLPRYSPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAGEHGPGLGLDPRVLFPPAPLPHKLLSRSPETCASPWKA
ESRSPSCSPGPAHPLSSRPFSALHDFHGHILARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQMVQARPGAHPTLLPGPTAAWVSGFSGG
GSDLTGAREAQERGRWSPTESSSASVSPVAKVSKFTLSSELEGGDYPKERERTGGGPGRPPDWTPHGTGAPAEPTPTHSPCTPPDTLPRP

--------------------------------------------------------------

>41489_41489_17_KCNMA1-HIVEP3_KCNMA1_chr10_78943179_ENST00000372443_HIVEP3_chr1_41984159_ENST00000247584_length(amino acids)=899AA_BP=286
MAAGGAPPSPCAGCPLLAMANGGGGGGGSSGGGGGGGGSSLRMSSNIHANHLSLDASSSSSSSSSSSSSSSSSSSSSSVHEPKMDALIIP
VTMEVPCDSRGQRMWWAFLASSMVTFFGGLFIILLWRTLKYLWTVCCHCGGKTKEAQKINNGSSQADGTLKPVDEKEEAVAAEVGWMTSV
KDWAGVMISAQTLTGRVLVVLVFALSIGALVIYFIDSSNPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDF
FTVPPVFVSVYLNRSWLGNLTKHMKSKAHSKKCQETGVLEELEAEEGTSDDLFQDSEGREGSEAVEEHQFSDLEDSDSDSDLDEDEDEDE
EESQDELSRPSSEAPPPGPPHALRADSSPILGPQPPDAPASGTEATRGSSVSEAERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSA
LSYKPVSPRRPWSPSKEAGSRPPLARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLTLCPLGRELAP
RAHVLSKLEGTTDPGLPRYSPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAGEHGPGLGLDPRVLFPPAPLPHKLLSRSPETCASPWQK
AESRSPSCSPGPAHPLSSRPFSALHDFHGHILARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQMVQARPGAHPTLLPGPTAAWVSGFSG
GGSDLTGAREAQERGRWSPTESSSASVSPVAKVSKFTLSSELEGGDYPKERERTGGGPGRPPDWTPHGTGAPAEPTPTHSPCTPPDTLPR

--------------------------------------------------------------

>41489_41489_18_KCNMA1-HIVEP3_KCNMA1_chr10_78943179_ENST00000372443_HIVEP3_chr1_41984159_ENST00000372583_length(amino acids)=899AA_BP=286
MAAGGAPPSPCAGCPLLAMANGGGGGGGSSGGGGGGGGSSLRMSSNIHANHLSLDASSSSSSSSSSSSSSSSSSSSSSVHEPKMDALIIP
VTMEVPCDSRGQRMWWAFLASSMVTFFGGLFIILLWRTLKYLWTVCCHCGGKTKEAQKINNGSSQADGTLKPVDEKEEAVAAEVGWMTSV
KDWAGVMISAQTLTGRVLVVLVFALSIGALVIYFIDSSNPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDF
FTVPPVFVSVYLNRSWLGNLTKHMKSKAHSKKCQETGVLEELEAEEGTSDDLFQDSEGREGSEAVEEHQFSDLEDSDSDSDLDEDEDEDE
EESQDELSRPSSEAPPPGPPHALRADSSPILGPQPPDAPASGTEATRGSSVSEAERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSA
LSYKPVSPRRPWSPSKEAGSRPPLARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLTLCPLGRELAP
RAHVLSKLEGTTDPGLPRYSPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAGEHGPGLGLDPRVLFPPAPLPHKLLSRSPETCASPWQK
AESRSPSCSPGPAHPLSSRPFSALHDFHGHILARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQMVQARPGAHPTLLPGPTAAWVSGFSG
GGSDLTGAREAQERGRWSPTESSSASVSPVAKVSKFTLSSELEGGDYPKERERTGGGPGRPPDWTPHGTGAPAEPTPTHSPCTPPDTLPR

--------------------------------------------------------------

>41489_41489_19_KCNMA1-HIVEP3_KCNMA1_chr10_78943179_ENST00000372443_HIVEP3_chr1_41984159_ENST00000372584_length(amino acids)=898AA_BP=286
MAAGGAPPSPCAGCPLLAMANGGGGGGGSSGGGGGGGGSSLRMSSNIHANHLSLDASSSSSSSSSSSSSSSSSSSSSSVHEPKMDALIIP
VTMEVPCDSRGQRMWWAFLASSMVTFFGGLFIILLWRTLKYLWTVCCHCGGKTKEAQKINNGSSQADGTLKPVDEKEEAVAAEVGWMTSV
KDWAGVMISAQTLTGRVLVVLVFALSIGALVIYFIDSSNPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDF
FTVPPVFVSVYLNRSWLGNLTKHMKSKAHSKKCQETGVLEELEAEEGTSDDLFQDSEGREGSEAVEEHQFSDLEDSDSDSDLDEDEDEDE
EESQDELSRPSSEAPPPGPPHALRADSSPILGPQPPDAPASGTEATRGSSVSEAERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSA
LSYKPVSPRRPWSPSKEAGSRPPLARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLTLCPLGRELAP
RAHVLSKLEGTTDPGLPRYSPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAGEHGPGLGLDPRVLFPPAPLPHKLLSRSPETCASPWKA
ESRSPSCSPGPAHPLSSRPFSALHDFHGHILARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQMVQARPGAHPTLLPGPTAAWVSGFSGG
GSDLTGAREAQERGRWSPTESSSASVSPVAKVSKFTLSSELEGGDYPKERERTGGGPGRPPDWTPHGTGAPAEPTPTHSPCTPPDTLPRP

--------------------------------------------------------------

>41489_41489_20_KCNMA1-HIVEP3_KCNMA1_chr10_78943179_ENST00000372443_HIVEP3_chr1_41984159_ENST00000429157_length(amino acids)=899AA_BP=286
MAAGGAPPSPCAGCPLLAMANGGGGGGGSSGGGGGGGGSSLRMSSNIHANHLSLDASSSSSSSSSSSSSSSSSSSSSSVHEPKMDALIIP
VTMEVPCDSRGQRMWWAFLASSMVTFFGGLFIILLWRTLKYLWTVCCHCGGKTKEAQKINNGSSQADGTLKPVDEKEEAVAAEVGWMTSV
KDWAGVMISAQTLTGRVLVVLVFALSIGALVIYFIDSSNPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDF
FTVPPVFVSVYLNRSWLGNLTKHMKSKAHSKKCQETGVLEELEAEEGTSDDLFQDSEGREGSEAVEEHQFSDLEDSDSDSDLDEDEDEDE
EESQDELSRPSSEAPPPGPPHALRADSSPILGPQPPDAPASGTEATRGSSVSEAERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSA
LSYKPVSPRRPWSPSKEAGSRPPLARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLTLCPLGRELAP
RAHVLSKLEGTTDPGLPRYSPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAGEHGPGLGLDPRVLFPPAPLPHKLLSRSPETCASPWKA
ESRSPSCSPGPAHPLSSRPFSALHDFHGHILARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQMVQARPGAHPTLLPGPTAAWVSGFSGG
GSDLTGAREAQERGRWSPTESSSASVSPVAKVSKFTLSSELEGGDYPKERERTGGGPGRPPDWTPHGTGAPAEPTPTHSPCTPPDTLPRP

--------------------------------------------------------------

>41489_41489_21_KCNMA1-HIVEP3_KCNMA1_chr10_78943179_ENST00000404771_HIVEP3_chr1_41984159_ENST00000247584_length(amino acids)=899AA_BP=286
MAAGGAPPSPCAGCPLLAMANGGGGGGGSSGGGGGGGGSSLRMSSNIHANHLSLDASSSSSSSSSSSSSSSSSSSSSSVHEPKMDALIIP
VTMEVPCDSRGQRMWWAFLASSMVTFFGGLFIILLWRTLKYLWTVCCHCGGKTKEAQKINNGSSQADGTLKPVDEKEEAVAAEVGWMTSV
KDWAGVMISAQTLTGRVLVVLVFALSIGALVIYFIDSSNPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDF
FTVPPVFVSVYLNRSWLGNLTKHMKSKAHSKKCQETGVLEELEAEEGTSDDLFQDSEGREGSEAVEEHQFSDLEDSDSDSDLDEDEDEDE
EESQDELSRPSSEAPPPGPPHALRADSSPILGPQPPDAPASGTEATRGSSVSEAERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSA
LSYKPVSPRRPWSPSKEAGSRPPLARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLTLCPLGRELAP
RAHVLSKLEGTTDPGLPRYSPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAGEHGPGLGLDPRVLFPPAPLPHKLLSRSPETCASPWQK
AESRSPSCSPGPAHPLSSRPFSALHDFHGHILARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQMVQARPGAHPTLLPGPTAAWVSGFSG
GGSDLTGAREAQERGRWSPTESSSASVSPVAKVSKFTLSSELEGGDYPKERERTGGGPGRPPDWTPHGTGAPAEPTPTHSPCTPPDTLPR

--------------------------------------------------------------

>41489_41489_22_KCNMA1-HIVEP3_KCNMA1_chr10_78943179_ENST00000404771_HIVEP3_chr1_41984159_ENST00000372583_length(amino acids)=899AA_BP=286
MAAGGAPPSPCAGCPLLAMANGGGGGGGSSGGGGGGGGSSLRMSSNIHANHLSLDASSSSSSSSSSSSSSSSSSSSSSVHEPKMDALIIP
VTMEVPCDSRGQRMWWAFLASSMVTFFGGLFIILLWRTLKYLWTVCCHCGGKTKEAQKINNGSSQADGTLKPVDEKEEAVAAEVGWMTSV
KDWAGVMISAQTLTGRVLVVLVFALSIGALVIYFIDSSNPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDF
FTVPPVFVSVYLNRSWLGNLTKHMKSKAHSKKCQETGVLEELEAEEGTSDDLFQDSEGREGSEAVEEHQFSDLEDSDSDSDLDEDEDEDE
EESQDELSRPSSEAPPPGPPHALRADSSPILGPQPPDAPASGTEATRGSSVSEAERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSA
LSYKPVSPRRPWSPSKEAGSRPPLARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLTLCPLGRELAP
RAHVLSKLEGTTDPGLPRYSPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAGEHGPGLGLDPRVLFPPAPLPHKLLSRSPETCASPWQK
AESRSPSCSPGPAHPLSSRPFSALHDFHGHILARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQMVQARPGAHPTLLPGPTAAWVSGFSG
GGSDLTGAREAQERGRWSPTESSSASVSPVAKVSKFTLSSELEGGDYPKERERTGGGPGRPPDWTPHGTGAPAEPTPTHSPCTPPDTLPR

--------------------------------------------------------------

>41489_41489_23_KCNMA1-HIVEP3_KCNMA1_chr10_78943179_ENST00000404771_HIVEP3_chr1_41984159_ENST00000372584_length(amino acids)=898AA_BP=286
MAAGGAPPSPCAGCPLLAMANGGGGGGGSSGGGGGGGGSSLRMSSNIHANHLSLDASSSSSSSSSSSSSSSSSSSSSSVHEPKMDALIIP
VTMEVPCDSRGQRMWWAFLASSMVTFFGGLFIILLWRTLKYLWTVCCHCGGKTKEAQKINNGSSQADGTLKPVDEKEEAVAAEVGWMTSV
KDWAGVMISAQTLTGRVLVVLVFALSIGALVIYFIDSSNPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDF
FTVPPVFVSVYLNRSWLGNLTKHMKSKAHSKKCQETGVLEELEAEEGTSDDLFQDSEGREGSEAVEEHQFSDLEDSDSDSDLDEDEDEDE
EESQDELSRPSSEAPPPGPPHALRADSSPILGPQPPDAPASGTEATRGSSVSEAERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSA
LSYKPVSPRRPWSPSKEAGSRPPLARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLTLCPLGRELAP
RAHVLSKLEGTTDPGLPRYSPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAGEHGPGLGLDPRVLFPPAPLPHKLLSRSPETCASPWKA
ESRSPSCSPGPAHPLSSRPFSALHDFHGHILARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQMVQARPGAHPTLLPGPTAAWVSGFSGG
GSDLTGAREAQERGRWSPTESSSASVSPVAKVSKFTLSSELEGGDYPKERERTGGGPGRPPDWTPHGTGAPAEPTPTHSPCTPPDTLPRP

--------------------------------------------------------------

>41489_41489_24_KCNMA1-HIVEP3_KCNMA1_chr10_78943179_ENST00000404771_HIVEP3_chr1_41984159_ENST00000429157_length(amino acids)=899AA_BP=286
MAAGGAPPSPCAGCPLLAMANGGGGGGGSSGGGGGGGGSSLRMSSNIHANHLSLDASSSSSSSSSSSSSSSSSSSSSSVHEPKMDALIIP
VTMEVPCDSRGQRMWWAFLASSMVTFFGGLFIILLWRTLKYLWTVCCHCGGKTKEAQKINNGSSQADGTLKPVDEKEEAVAAEVGWMTSV
KDWAGVMISAQTLTGRVLVVLVFALSIGALVIYFIDSSNPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDF
FTVPPVFVSVYLNRSWLGNLTKHMKSKAHSKKCQETGVLEELEAEEGTSDDLFQDSEGREGSEAVEEHQFSDLEDSDSDSDLDEDEDEDE
EESQDELSRPSSEAPPPGPPHALRADSSPILGPQPPDAPASGTEATRGSSVSEAERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSA
LSYKPVSPRRPWSPSKEAGSRPPLARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLTLCPLGRELAP
RAHVLSKLEGTTDPGLPRYSPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAGEHGPGLGLDPRVLFPPAPLPHKLLSRSPETCASPWKA
ESRSPSCSPGPAHPLSSRPFSALHDFHGHILARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQMVQARPGAHPTLLPGPTAAWVSGFSGG
GSDLTGAREAQERGRWSPTESSSASVSPVAKVSKFTLSSELEGGDYPKERERTGGGPGRPPDWTPHGTGAPAEPTPTHSPCTPPDTLPRP

--------------------------------------------------------------

>41489_41489_25_KCNMA1-HIVEP3_KCNMA1_chr10_78943179_ENST00000404857_HIVEP3_chr1_41984159_ENST00000247584_length(amino acids)=881AA_BP=268
MANGGGGGGGSSGGGGGGGGSSLRMSSNIHANHLSLDASSSSSSSSSSSSSSSSSSSSSSVHEPKMDALIIPVTMEVPCDSRGQRMWWAF
LASSMVTFFGGLFIILLWRTLKYLWTVCCHCGGKTKEAQKINNGSSQADGTLKPVDEKEEAVAAEVGWMTSVKDWAGVMISAQTLTGRVL
VVLVFALSIGALVIYFIDSSNPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLG
NLTKHMKSKAHSKKCQETGVLEELEAEEGTSDDLFQDSEGREGSEAVEEHQFSDLEDSDSDSDLDEDEDEDEEESQDELSRPSSEAPPPG
PPHALRADSSPILGPQPPDAPASGTEATRGSSVSEAERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSALSYKPVSPRRPWSPSKEA
GSRPPLARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLTLCPLGRELAPRAHVLSKLEGTTDPGLPR
YSPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAGEHGPGLGLDPRVLFPPAPLPHKLLSRSPETCASPWQKAESRSPSCSPGPAHPLSS
RPFSALHDFHGHILARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQMVQARPGAHPTLLPGPTAAWVSGFSGGGSDLTGAREAQERGRWS
PTESSSASVSPVAKVSKFTLSSELEGGDYPKERERTGGGPGRPPDWTPHGTGAPAEPTPTHSPCTPPDTLPRPPQGRRAAQSWSPRLESP

--------------------------------------------------------------

>41489_41489_26_KCNMA1-HIVEP3_KCNMA1_chr10_78943179_ENST00000404857_HIVEP3_chr1_41984159_ENST00000372583_length(amino acids)=881AA_BP=268
MANGGGGGGGSSGGGGGGGGSSLRMSSNIHANHLSLDASSSSSSSSSSSSSSSSSSSSSSVHEPKMDALIIPVTMEVPCDSRGQRMWWAF
LASSMVTFFGGLFIILLWRTLKYLWTVCCHCGGKTKEAQKINNGSSQADGTLKPVDEKEEAVAAEVGWMTSVKDWAGVMISAQTLTGRVL
VVLVFALSIGALVIYFIDSSNPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLG
NLTKHMKSKAHSKKCQETGVLEELEAEEGTSDDLFQDSEGREGSEAVEEHQFSDLEDSDSDSDLDEDEDEDEEESQDELSRPSSEAPPPG
PPHALRADSSPILGPQPPDAPASGTEATRGSSVSEAERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSALSYKPVSPRRPWSPSKEA
GSRPPLARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLTLCPLGRELAPRAHVLSKLEGTTDPGLPR
YSPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAGEHGPGLGLDPRVLFPPAPLPHKLLSRSPETCASPWQKAESRSPSCSPGPAHPLSS
RPFSALHDFHGHILARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQMVQARPGAHPTLLPGPTAAWVSGFSGGGSDLTGAREAQERGRWS
PTESSSASVSPVAKVSKFTLSSELEGGDYPKERERTGGGPGRPPDWTPHGTGAPAEPTPTHSPCTPPDTLPRPPQGRRAAQSWSPRLESP

--------------------------------------------------------------

>41489_41489_27_KCNMA1-HIVEP3_KCNMA1_chr10_78943179_ENST00000404857_HIVEP3_chr1_41984159_ENST00000372584_length(amino acids)=880AA_BP=268
MANGGGGGGGSSGGGGGGGGSSLRMSSNIHANHLSLDASSSSSSSSSSSSSSSSSSSSSSVHEPKMDALIIPVTMEVPCDSRGQRMWWAF
LASSMVTFFGGLFIILLWRTLKYLWTVCCHCGGKTKEAQKINNGSSQADGTLKPVDEKEEAVAAEVGWMTSVKDWAGVMISAQTLTGRVL
VVLVFALSIGALVIYFIDSSNPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLG
NLTKHMKSKAHSKKCQETGVLEELEAEEGTSDDLFQDSEGREGSEAVEEHQFSDLEDSDSDSDLDEDEDEDEEESQDELSRPSSEAPPPG
PPHALRADSSPILGPQPPDAPASGTEATRGSSVSEAERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSALSYKPVSPRRPWSPSKEA
GSRPPLARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLTLCPLGRELAPRAHVLSKLEGTTDPGLPR
YSPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAGEHGPGLGLDPRVLFPPAPLPHKLLSRSPETCASPWKAESRSPSCSPGPAHPLSSR
PFSALHDFHGHILARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQMVQARPGAHPTLLPGPTAAWVSGFSGGGSDLTGAREAQERGRWSP
TESSSASVSPVAKVSKFTLSSELEGGDYPKERERTGGGPGRPPDWTPHGTGAPAEPTPTHSPCTPPDTLPRPPQGRRAAQSWSPRLESPR

--------------------------------------------------------------

>41489_41489_28_KCNMA1-HIVEP3_KCNMA1_chr10_78943179_ENST00000404857_HIVEP3_chr1_41984159_ENST00000429157_length(amino acids)=880AA_BP=268
MANGGGGGGGSSGGGGGGGGSSLRMSSNIHANHLSLDASSSSSSSSSSSSSSSSSSSSSSVHEPKMDALIIPVTMEVPCDSRGQRMWWAF
LASSMVTFFGGLFIILLWRTLKYLWTVCCHCGGKTKEAQKINNGSSQADGTLKPVDEKEEAVAAEVGWMTSVKDWAGVMISAQTLTGRVL
VVLVFALSIGALVIYFIDSSNPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLG
NLTKHMKSKAHSKKCQETGVLEELEAEEGTSDDLFQDSEGREGSEAVEEHQFSDLEDSDSDSDLDEDEDEDEEESQDELSRPSSEAPPPG
PPHALRADSSPILGPQPPDAPASGTEATRGSSVSEAERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSALSYKPVSPRRPWSPSKEA
GSRPPLARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLTLCPLGRELAPRAHVLSKLEGTTDPGLPR
YSPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAGEHGPGLGLDPRVLFPPAPLPHKLLSRSPETCASPWKAESRSPSCSPGPAHPLSSR
PFSALHDFHGHILARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQMVQARPGAHPTLLPGPTAAWVSGFSGGGSDLTGAREAQERGRWSP
TESSSASVSPVAKVSKFTLSSELEGGDYPKERERTGGGPGRPPDWTPHGTGAPAEPTPTHSPCTPPDTLPRPPQGRRAAQSWSPRLESPR

--------------------------------------------------------------

>41489_41489_29_KCNMA1-HIVEP3_KCNMA1_chr10_78943179_ENST00000406533_HIVEP3_chr1_41984159_ENST00000247584_length(amino acids)=881AA_BP=268
MANGGGGGGGSSGGGGGGGGSSLRMSSNIHANHLSLDASSSSSSSSSSSSSSSSSSSSSSVHEPKMDALIIPVTMEVPCDSRGQRMWWAF
LASSMVTFFGGLFIILLWRTLKYLWTVCCHCGGKTKEAQKINNGSSQADGTLKPVDEKEEAVAAEVGWMTSVKDWAGVMISAQTLTGRVL
VVLVFALSIGALVIYFIDSSNPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLG
NLTKHMKSKAHSKKCQETGVLEELEAEEGTSDDLFQDSEGREGSEAVEEHQFSDLEDSDSDSDLDEDEDEDEEESQDELSRPSSEAPPPG
PPHALRADSSPILGPQPPDAPASGTEATRGSSVSEAERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSALSYKPVSPRRPWSPSKEA
GSRPPLARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLTLCPLGRELAPRAHVLSKLEGTTDPGLPR
YSPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAGEHGPGLGLDPRVLFPPAPLPHKLLSRSPETCASPWQKAESRSPSCSPGPAHPLSS
RPFSALHDFHGHILARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQMVQARPGAHPTLLPGPTAAWVSGFSGGGSDLTGAREAQERGRWS
PTESSSASVSPVAKVSKFTLSSELEGGDYPKERERTGGGPGRPPDWTPHGTGAPAEPTPTHSPCTPPDTLPRPPQGRRAAQSWSPRLESP

--------------------------------------------------------------

>41489_41489_30_KCNMA1-HIVEP3_KCNMA1_chr10_78943179_ENST00000406533_HIVEP3_chr1_41984159_ENST00000372583_length(amino acids)=881AA_BP=268
MANGGGGGGGSSGGGGGGGGSSLRMSSNIHANHLSLDASSSSSSSSSSSSSSSSSSSSSSVHEPKMDALIIPVTMEVPCDSRGQRMWWAF
LASSMVTFFGGLFIILLWRTLKYLWTVCCHCGGKTKEAQKINNGSSQADGTLKPVDEKEEAVAAEVGWMTSVKDWAGVMISAQTLTGRVL
VVLVFALSIGALVIYFIDSSNPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLG
NLTKHMKSKAHSKKCQETGVLEELEAEEGTSDDLFQDSEGREGSEAVEEHQFSDLEDSDSDSDLDEDEDEDEEESQDELSRPSSEAPPPG
PPHALRADSSPILGPQPPDAPASGTEATRGSSVSEAERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSALSYKPVSPRRPWSPSKEA
GSRPPLARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLTLCPLGRELAPRAHVLSKLEGTTDPGLPR
YSPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAGEHGPGLGLDPRVLFPPAPLPHKLLSRSPETCASPWQKAESRSPSCSPGPAHPLSS
RPFSALHDFHGHILARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQMVQARPGAHPTLLPGPTAAWVSGFSGGGSDLTGAREAQERGRWS
PTESSSASVSPVAKVSKFTLSSELEGGDYPKERERTGGGPGRPPDWTPHGTGAPAEPTPTHSPCTPPDTLPRPPQGRRAAQSWSPRLESP

--------------------------------------------------------------

>41489_41489_31_KCNMA1-HIVEP3_KCNMA1_chr10_78943179_ENST00000406533_HIVEP3_chr1_41984159_ENST00000372584_length(amino acids)=880AA_BP=268
MANGGGGGGGSSGGGGGGGGSSLRMSSNIHANHLSLDASSSSSSSSSSSSSSSSSSSSSSVHEPKMDALIIPVTMEVPCDSRGQRMWWAF
LASSMVTFFGGLFIILLWRTLKYLWTVCCHCGGKTKEAQKINNGSSQADGTLKPVDEKEEAVAAEVGWMTSVKDWAGVMISAQTLTGRVL
VVLVFALSIGALVIYFIDSSNPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLG
NLTKHMKSKAHSKKCQETGVLEELEAEEGTSDDLFQDSEGREGSEAVEEHQFSDLEDSDSDSDLDEDEDEDEEESQDELSRPSSEAPPPG
PPHALRADSSPILGPQPPDAPASGTEATRGSSVSEAERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSALSYKPVSPRRPWSPSKEA
GSRPPLARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLTLCPLGRELAPRAHVLSKLEGTTDPGLPR
YSPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAGEHGPGLGLDPRVLFPPAPLPHKLLSRSPETCASPWKAESRSPSCSPGPAHPLSSR
PFSALHDFHGHILARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQMVQARPGAHPTLLPGPTAAWVSGFSGGGSDLTGAREAQERGRWSP
TESSSASVSPVAKVSKFTLSSELEGGDYPKERERTGGGPGRPPDWTPHGTGAPAEPTPTHSPCTPPDTLPRPPQGRRAAQSWSPRLESPR

--------------------------------------------------------------

>41489_41489_32_KCNMA1-HIVEP3_KCNMA1_chr10_78943179_ENST00000406533_HIVEP3_chr1_41984159_ENST00000429157_length(amino acids)=880AA_BP=268
MANGGGGGGGSSGGGGGGGGSSLRMSSNIHANHLSLDASSSSSSSSSSSSSSSSSSSSSSVHEPKMDALIIPVTMEVPCDSRGQRMWWAF
LASSMVTFFGGLFIILLWRTLKYLWTVCCHCGGKTKEAQKINNGSSQADGTLKPVDEKEEAVAAEVGWMTSVKDWAGVMISAQTLTGRVL
VVLVFALSIGALVIYFIDSSNPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLG
NLTKHMKSKAHSKKCQETGVLEELEAEEGTSDDLFQDSEGREGSEAVEEHQFSDLEDSDSDSDLDEDEDEDEEESQDELSRPSSEAPPPG
PPHALRADSSPILGPQPPDAPASGTEATRGSSVSEAERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSALSYKPVSPRRPWSPSKEA
GSRPPLARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLTLCPLGRELAPRAHVLSKLEGTTDPGLPR
YSPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAGEHGPGLGLDPRVLFPPAPLPHKLLSRSPETCASPWKAESRSPSCSPGPAHPLSSR
PFSALHDFHGHILARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQMVQARPGAHPTLLPGPTAAWVSGFSGGGSDLTGAREAQERGRWSP
TESSSASVSPVAKVSKFTLSSELEGGDYPKERERTGGGPGRPPDWTPHGTGAPAEPTPTHSPCTPPDTLPRPPQGRRAAQSWSPRLESPR

--------------------------------------------------------------

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Fusion Protein Functional Features

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr10:78943179/chr1:41984159)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
KCNMA1 Q12791	HIVEP3 Q5T1R4
FUNCTION: Potassium channel activated by both membrane depolarization or increase in cytosolic Ca(2+) that mediates export of K(+) (PubMed:29330545, PubMed:31152168). It is also activated by the concentration of cytosolic Mg(2+). Its activation dampens the excitatory events that elevate the cytosolic Ca(2+) concentration and/or depolarize the cell membrane. It therefore contributes to repolarization of the membrane potential. Plays a key role in controlling excitability in a number of systems, such as regulation of the contraction of smooth muscle, the tuning of hair cells in the cochlea, regulation of transmitter release, and innate immunity. In smooth muscles, its activation by high level of Ca(2+), caused by ryanodine receptors in the sarcoplasmic reticulum, regulates the membrane potential. In cochlea cells, its number and kinetic properties partly determine the characteristic frequency of each hair cell and thereby helps to establish a tonotopic map. Kinetics of KCNMA1 channels are determined by alternative splicing, phosphorylation status and its combination with modulating beta subunits. Highly sensitive to both iberiotoxin (IbTx) and charybdotoxin (CTX). {ECO:0000269\|PubMed:29330545, ECO:0000269\|PubMed:31152168}.	FUNCTION: Plays a role of transcription factor; binds to recognition signal sequences (Rss heptamer) for somatic recombination of immunoglobulin and T-cell receptor gene segments; Binds also to the kappa-B motif of gene such as S100A4, involved in cell progression and differentiation. Kappa-B motif is a gene regulatory element found in promoters and enhancers of genes involved in immunity, inflammation, and growth and that responds to viral antigens, mitogens, and cytokines. Involvement of HIVEP3 in cell growth is strengthened by the fact that its down-regulation promotes cell cycle progression with ultimate formation of multinucleated giant cells. Strongly inhibits TNF-alpha-induced NF-kappa-B activation; Interferes with nuclear factor NF-kappa-B by several mechanisms: as transcription factor, by competing for Kappa-B motif and by repressing transcription in the nucleus; through a non transcriptional process, by inhibiting nuclear translocation of RELA by association with TRAF2, an adapter molecule in the tumor necrosis factor signaling, which blocks the formation of IKK complex. Interaction with TRAF proteins inhibits both NF-Kappa-B-mediated and c-Jun N-terminal kinase/JNK-mediated responses that include apoptosis and proinflammatory cytokine gene expression. Positively regulates the expression of IL2 in T-cell. Essential regulator of adult bone formation. {ECO:0000269\|PubMed:11161801}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page
* Minus value of BPloci means that the break pointn is located before the CDS.

- Retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000286627

13_20

269.3333333333333

1179.0

Compositional bias

Note=Poly-Gly

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000286627

39_60

269.3333333333333

1179.0

Compositional bias

Note=Poly-Ser

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000286627

4_10

269.3333333333333

1179.0

Compositional bias

Note=Poly-Gly

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000286628

13_20

269.3333333333333

1237.0

Compositional bias

Note=Poly-Gly

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000286628

39_60

269.3333333333333

1237.0

Compositional bias

Note=Poly-Ser

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000286628

4_10

269.3333333333333

1237.0

Compositional bias

Note=Poly-Gly

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000404857

13_20

269.3333333333333

1220.0

Compositional bias

Note=Poly-Gly

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000404857

39_60

269.3333333333333

1220.0

Compositional bias

Note=Poly-Ser

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000404857

4_10

269.3333333333333

1220.0

Compositional bias

Note=Poly-Gly

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000286627

108_178

269.3333333333333

1179.0

Topological domain

Cytoplasmic

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000286627

1_86

269.3333333333333

1179.0

Topological domain

Extracellular

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000286627

200_214

269.3333333333333

1179.0

Topological domain

Extracellular

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000286627

236_239

269.3333333333333

1179.0

Topological domain

Cytoplasmic

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000286627

261_264

269.3333333333333

1179.0

Topological domain

Extracellular

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000286628

108_178

269.3333333333333

1237.0

Topological domain

Cytoplasmic

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000286628

1_86

269.3333333333333

1237.0

Topological domain

Extracellular

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000286628

200_214

269.3333333333333

1237.0

Topological domain

Extracellular

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000286628

236_239

269.3333333333333

1237.0

Topological domain

Cytoplasmic

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000286628

261_264

269.3333333333333

1237.0

Topological domain

Extracellular

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000404857

108_178

269.3333333333333

1220.0

Topological domain

Cytoplasmic

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000404857

1_86

269.3333333333333

1220.0

Topological domain

Extracellular

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000404857

200_214

269.3333333333333

1220.0

Topological domain

Extracellular

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000404857

236_239

269.3333333333333

1220.0

Topological domain

Cytoplasmic

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000404857

261_264

269.3333333333333

1220.0

Topological domain

Extracellular

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000286627

179_199

269.3333333333333

1179.0

Transmembrane

Helical%3B Name%3DSegment S1

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000286627

215_235

269.3333333333333

1179.0

Transmembrane

Helical%3B Name%3DSegment S2

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000286627

240_260

269.3333333333333

1179.0

Transmembrane

Helical%3B Name%3DSegment S3

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000286627

87_107

269.3333333333333

1179.0

Transmembrane

Helical%3B Name%3DSegment S0

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000286628

179_199

269.3333333333333

1237.0

Transmembrane

Helical%3B Name%3DSegment S1

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000286628

215_235

269.3333333333333

1237.0

Transmembrane

Helical%3B Name%3DSegment S2

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000286628

240_260

269.3333333333333

1237.0

Transmembrane

Helical%3B Name%3DSegment S3

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000286628

87_107

269.3333333333333

1237.0

Transmembrane

Helical%3B Name%3DSegment S0

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000404857

179_199

269.3333333333333

1220.0

Transmembrane

Helical%3B Name%3DSegment S1

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000404857

215_235

269.3333333333333

1220.0

Transmembrane

Helical%3B Name%3DSegment S2

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000404857

240_260

269.3333333333333

1220.0

Transmembrane

Helical%3B Name%3DSegment S3

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000404857

87_107

269.3333333333333

1220.0

Transmembrane

Helical%3B Name%3DSegment S0

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000247584

1907_1936

1794.3333333333333

2407.0

Compositional bias

Note=Ser-rich

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000372583

1907_1936

1794.3333333333333

2407.0

Compositional bias

Note=Ser-rich

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000372584

1907_1936

1794.3333333333333

2406.0

Compositional bias

Note=Ser-rich

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000429157

1907_1936

1794.3333333333333

2406.0

Compositional bias

Note=Ser-rich

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000247584

1817_1872

1794.3333333333333

2407.0

Region

Note=Acidic 3

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000247584

2053_2148

1794.3333333333333

2407.0

Region

Note=6 X 4 AA tandem repeats of S-P-X-[RK]

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000372583

1817_1872

1794.3333333333333

2407.0

Region

Note=Acidic 3

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000372583

2053_2148

1794.3333333333333

2407.0

Region

Note=6 X 4 AA tandem repeats of S-P-X-[RK]

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000372584

1817_1872

1794.3333333333333

2406.0

Region

Note=Acidic 3

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000372584

2053_2148

1794.3333333333333

2406.0

Region

Note=6 X 4 AA tandem repeats of S-P-X-[RK]

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000429157

1817_1872

1794.3333333333333

2406.0

Region

Note=Acidic 3

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000429157

2053_2148

1794.3333333333333

2406.0

Region

Note=6 X 4 AA tandem repeats of S-P-X-[RK]

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000247584

1964_1967

1794.3333333333333

2407.0

Repeat

Note=1

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000247584

1970_1973

1794.3333333333333

2407.0

Repeat

Note=2

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000247584

1993_1996

1794.3333333333333

2407.0

Repeat

Note=3

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000247584

1998_2001

1794.3333333333333

2407.0

Repeat

Note=4

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000247584

2067_2070

1794.3333333333333

2407.0

Repeat

Note=5

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000247584

2079_2082

1794.3333333333333

2407.0

Repeat

Note=6

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000372583

1964_1967

1794.3333333333333

2407.0

Repeat

Note=1

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000372583

1970_1973

1794.3333333333333

2407.0

Repeat

Note=2

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000372583

1993_1996

1794.3333333333333

2407.0

Repeat

Note=3

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000372583

1998_2001

1794.3333333333333

2407.0

Repeat

Note=4

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000372583

2067_2070

1794.3333333333333

2407.0

Repeat

Note=5

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000372583

2079_2082

1794.3333333333333

2407.0

Repeat

Note=6

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000372584

1964_1967

1794.3333333333333

2406.0

Repeat

Note=1

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000372584

1970_1973

1794.3333333333333

2406.0

Repeat

Note=2

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000372584

1993_1996

1794.3333333333333

2406.0

Repeat

Note=3

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000372584

1998_2001

1794.3333333333333

2406.0

Repeat

Note=4

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000372584

2067_2070

1794.3333333333333

2406.0

Repeat

Note=5

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000372584

2079_2082

1794.3333333333333

2406.0

Repeat

Note=6

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000429157

1964_1967

1794.3333333333333

2406.0

Repeat

Note=1

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000429157

1970_1973

1794.3333333333333

2406.0

Repeat

Note=2

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000429157

1993_1996

1794.3333333333333

2406.0

Repeat

Note=3

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000429157

1998_2001

1794.3333333333333

2406.0

Repeat

Note=4

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000429157

2067_2070

1794.3333333333333

2406.0

Repeat

Note=5

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000429157

2079_2082

1794.3333333333333

2406.0

Repeat

Note=6

- Not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000480683

13_20

169.0

Compositional bias

Note=Poly-Gly

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000480683

39_60

169.0

Compositional bias

Note=Poly-Ser

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000480683

4_10

169.0

Compositional bias

Note=Poly-Gly

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000286627

415_558

269.3333333333333

1179.0

Domain

Note=RCK N-terminal

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000286628

415_558

269.3333333333333

1237.0

Domain

Note=RCK N-terminal

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000404857

415_558

269.3333333333333

1220.0

Domain

Note=RCK N-terminal

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000480683

415_558

169.0

Domain

Note=RCK N-terminal

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000286627

336_358

269.3333333333333

1179.0

Intramembrane

Pore-forming%3B Name%3DP region

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000286628

336_358

269.3333333333333

1237.0

Intramembrane

Pore-forming%3B Name%3DP region

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000404857

336_358

269.3333333333333

1220.0

Intramembrane

Pore-forming%3B Name%3DP region

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000480683

336_358

169.0

Intramembrane

Pore-forming%3B Name%3DP region

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000286627

1003_1025

269.3333333333333

1179.0

Motif

Note=Calcium bowl

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000286627

352_355

269.3333333333333

1179.0

Motif

Note=Selectivity for potassium

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000286628

1003_1025

269.3333333333333

1237.0

Motif

Note=Calcium bowl

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000286628

352_355

269.3333333333333

1237.0

Motif

Note=Selectivity for potassium

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000404857

1003_1025

269.3333333333333

1220.0

Motif

Note=Calcium bowl

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000404857

352_355

269.3333333333333

1220.0

Motif

Note=Selectivity for potassium

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000480683

1003_1025

169.0

Motif

Note=Calcium bowl

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000480683

352_355

169.0

Motif

Note=Selectivity for potassium

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000286627

1032_1052

269.3333333333333

1179.0

Region

Note=Segment S10

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000286627

556_576

269.3333333333333

1179.0

Region

Note=Segment S7

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000286627

613_633

269.3333333333333

1179.0

Region

Note=Segment S8

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000286627

677_681

269.3333333333333

1179.0

Region

Note=Heme-binding motif

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000286627

837_857

269.3333333333333

1179.0

Region

Note=Segment S9

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000286628

1032_1052

269.3333333333333

1237.0

Region

Note=Segment S10

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000286628

556_576

269.3333333333333

1237.0

Region

Note=Segment S7

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000286628

613_633

269.3333333333333

1237.0

Region

Note=Segment S8

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000286628

677_681

269.3333333333333

1237.0

Region

Note=Heme-binding motif

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000286628

837_857

269.3333333333333

1237.0

Region

Note=Segment S9

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000404857

1032_1052

269.3333333333333

1220.0

Region

Note=Segment S10

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000404857

556_576

269.3333333333333

1220.0

Region

Note=Segment S7

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000404857

613_633

269.3333333333333

1220.0

Region

Note=Segment S8

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000404857

677_681

269.3333333333333

1220.0

Region

Note=Heme-binding motif

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000404857

837_857

269.3333333333333

1220.0

Region

Note=Segment S9

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000480683

1032_1052

169.0

Region

Note=Segment S10

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000480683

556_576

169.0

Region

Note=Segment S7

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000480683

613_633

169.0

Region

Note=Segment S8

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000480683

677_681

169.0

Region

Note=Heme-binding motif

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000480683

837_857

169.0

Region

Note=Segment S9

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000286627

286_300

269.3333333333333

1179.0

Topological domain

Cytoplasmic

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000286627

322_335

269.3333333333333

1179.0

Topological domain

Extracellular

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000286627

359_367

269.3333333333333

1179.0

Topological domain

Extracellular

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000286627

389_1236

269.3333333333333

1179.0

Topological domain

Cytoplasmic

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000286628

286_300

269.3333333333333

1237.0

Topological domain

Cytoplasmic

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000286628

322_335

269.3333333333333

1237.0

Topological domain

Extracellular

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000286628

359_367

269.3333333333333

1237.0

Topological domain

Extracellular

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000286628

389_1236

269.3333333333333

1237.0

Topological domain

Cytoplasmic

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000404857

286_300

269.3333333333333

1220.0

Topological domain

Cytoplasmic

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000404857

322_335

269.3333333333333

1220.0

Topological domain

Extracellular

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000404857

359_367

269.3333333333333

1220.0

Topological domain

Extracellular

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000404857

389_1236

269.3333333333333

1220.0

Topological domain

Cytoplasmic

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000480683

108_178

169.0

Topological domain

Cytoplasmic

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000480683

1_86

169.0

Topological domain

Extracellular

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000480683

200_214

169.0

Topological domain

Extracellular

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000480683

236_239

169.0

Topological domain

Cytoplasmic

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000480683

261_264

169.0

Topological domain

Extracellular

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000480683

286_300

169.0

Topological domain

Cytoplasmic

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000480683

322_335

169.0

Topological domain

Extracellular

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000480683

359_367

169.0

Topological domain

Extracellular

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000480683

389_1236

169.0

Topological domain

Cytoplasmic

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000286627

265_285

269.3333333333333

1179.0

Transmembrane

Helical%3B Name%3DSegment S4

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000286627

301_321

269.3333333333333

1179.0

Transmembrane

Helical%3B Name%3DSegment S5

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000286627

368_388

269.3333333333333

1179.0

Transmembrane

Helical%3B Name%3DSegment S6

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000286628

265_285

269.3333333333333

1237.0

Transmembrane

Helical%3B Name%3DSegment S4

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000286628

301_321

269.3333333333333

1237.0

Transmembrane

Helical%3B Name%3DSegment S5

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000286628

368_388

269.3333333333333

1237.0

Transmembrane

Helical%3B Name%3DSegment S6

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000404857

265_285

269.3333333333333

1220.0

Transmembrane

Helical%3B Name%3DSegment S4

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000404857

301_321

269.3333333333333

1220.0

Transmembrane

Helical%3B Name%3DSegment S5

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000404857

368_388

269.3333333333333

1220.0

Transmembrane

Helical%3B Name%3DSegment S6

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000480683

179_199

169.0

Transmembrane

Helical%3B Name%3DSegment S1

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000480683

215_235

169.0

Transmembrane

Helical%3B Name%3DSegment S2

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000480683

240_260

169.0

Transmembrane

Helical%3B Name%3DSegment S3

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000480683

265_285

169.0

Transmembrane

Helical%3B Name%3DSegment S4

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000480683

301_321

169.0

Transmembrane

Helical%3B Name%3DSegment S5

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000480683

368_388

169.0

Transmembrane

Helical%3B Name%3DSegment S6

Hgene

KCNMA1

chr10:78943179

chr1:41984159

ENST00000480683

87_107

169.0

Transmembrane

Helical%3B Name%3DSegment S0

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000247584

1442_1466

1794.3333333333333

2407.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000372583

1442_1466

1794.3333333333333

2407.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000372584

1442_1466

1794.3333333333333

2406.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000429157

1442_1466

1794.3333333333333

2406.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000247584

308_334

1794.3333333333333

2407.0

Compositional bias

Note=Ser-rich

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000247584

378_414

1794.3333333333333

2407.0

Compositional bias

Note=Ser-rich

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000247584

797_819

1794.3333333333333

2407.0

Compositional bias

Note=Ser-rich

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000247584

844_880

1794.3333333333333

2407.0

Compositional bias

Note=Glu/Pro-rich

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000247584

916_948

1794.3333333333333

2407.0

Compositional bias

Note=Ser-rich

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000372583

308_334

1794.3333333333333

2407.0

Compositional bias

Note=Ser-rich

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000372583

378_414

1794.3333333333333

2407.0

Compositional bias

Note=Ser-rich

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000372583

797_819

1794.3333333333333

2407.0

Compositional bias

Note=Ser-rich

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000372583

844_880

1794.3333333333333

2407.0

Compositional bias

Note=Glu/Pro-rich

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000372583

916_948

1794.3333333333333

2407.0

Compositional bias

Note=Ser-rich

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000372584

308_334

1794.3333333333333

2406.0

Compositional bias

Note=Ser-rich

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000372584

378_414

1794.3333333333333

2406.0

Compositional bias

Note=Ser-rich

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000372584

797_819

1794.3333333333333

2406.0

Compositional bias

Note=Ser-rich

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000372584

844_880

1794.3333333333333

2406.0

Compositional bias

Note=Glu/Pro-rich

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000372584

916_948

1794.3333333333333

2406.0

Compositional bias

Note=Ser-rich

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000429157

308_334

1794.3333333333333

2406.0

Compositional bias

Note=Ser-rich

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000429157

378_414

1794.3333333333333

2406.0

Compositional bias

Note=Ser-rich

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000429157

797_819

1794.3333333333333

2406.0

Compositional bias

Note=Ser-rich

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000429157

844_880

1794.3333333333333

2406.0

Compositional bias

Note=Glu/Pro-rich

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000429157

916_948

1794.3333333333333

2406.0

Compositional bias

Note=Ser-rich

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000247584

903_909

1794.3333333333333

2407.0

Motif

Nuclear localization signal

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000372583

903_909

1794.3333333333333

2407.0

Motif

Nuclear localization signal

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000372584

903_909

1794.3333333333333

2406.0

Motif

Nuclear localization signal

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000429157

903_909

1794.3333333333333

2406.0

Motif

Nuclear localization signal

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000247584

1754_1806

1794.3333333333333

2407.0

Region

Note=ZAS2

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000247584

192_242

1794.3333333333333

2407.0

Region

Note=ZAS1

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000247584

211_1074

1794.3333333333333

2407.0

Region

No DNA binding activity or transactivation activity%2C but complete prevention of TRAF-dependent NF-Kappa-B activation%3B associates with TRAF2 and JUN

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000247584

264_287

1794.3333333333333

2407.0

Region

Note=Acidic 1

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000247584

862_883

1794.3333333333333

2407.0

Region

Note=Acidic 2

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000372583

1754_1806

1794.3333333333333

2407.0

Region

Note=ZAS2

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000372583

192_242

1794.3333333333333

2407.0

Region

Note=ZAS1

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000372583

211_1074

1794.3333333333333

2407.0

Region

No DNA binding activity or transactivation activity%2C but complete prevention of TRAF-dependent NF-Kappa-B activation%3B associates with TRAF2 and JUN

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000372583

264_287

1794.3333333333333

2407.0

Region

Note=Acidic 1

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000372583

862_883

1794.3333333333333

2407.0

Region

Note=Acidic 2

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000372584

1754_1806

1794.3333333333333

2406.0

Region

Note=ZAS2

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000372584

192_242

1794.3333333333333

2406.0

Region

Note=ZAS1

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000372584

211_1074

1794.3333333333333

2406.0

Region

No DNA binding activity or transactivation activity%2C but complete prevention of TRAF-dependent NF-Kappa-B activation%3B associates with TRAF2 and JUN

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000372584

264_287

1794.3333333333333

2406.0

Region

Note=Acidic 1

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000372584

862_883

1794.3333333333333

2406.0

Region

Note=Acidic 2

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000429157

1754_1806

1794.3333333333333

2406.0

Region

Note=ZAS2

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000429157

192_242

1794.3333333333333

2406.0

Region

Note=ZAS1

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000429157

211_1074

1794.3333333333333

2406.0

Region

No DNA binding activity or transactivation activity%2C but complete prevention of TRAF-dependent NF-Kappa-B activation%3B associates with TRAF2 and JUN

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000429157

264_287

1794.3333333333333

2406.0

Region

Note=Acidic 1

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000429157

862_883

1794.3333333333333

2406.0

Region

Note=Acidic 2

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000247584

1754_1776

1794.3333333333333

2407.0

Zinc finger

C2H2-type 3

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000247584

1782_1806

1794.3333333333333

2407.0

Zinc finger

C2H2-type 4

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000247584

192_214

1794.3333333333333

2407.0

Zinc finger

C2H2-type 1

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000247584

220_242

1794.3333333333333

2407.0

Zinc finger

C2H2-type 2

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000247584

640_670

1794.3333333333333

2407.0

Zinc finger

CCHC HIVEP-type

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000372583

1754_1776

1794.3333333333333

2407.0

Zinc finger

C2H2-type 3

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000372583

1782_1806

1794.3333333333333

2407.0

Zinc finger

C2H2-type 4

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000372583

192_214

1794.3333333333333

2407.0

Zinc finger

C2H2-type 1

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000372583

220_242

1794.3333333333333

2407.0

Zinc finger

C2H2-type 2

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000372583

640_670

1794.3333333333333

2407.0

Zinc finger

CCHC HIVEP-type

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000372584

1754_1776

1794.3333333333333

2406.0

Zinc finger

C2H2-type 3

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000372584

1782_1806

1794.3333333333333

2406.0

Zinc finger

C2H2-type 4

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000372584

192_214

1794.3333333333333

2406.0

Zinc finger

C2H2-type 1

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000372584

220_242

1794.3333333333333

2406.0

Zinc finger

C2H2-type 2

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000372584

640_670

1794.3333333333333

2406.0

Zinc finger

CCHC HIVEP-type

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000429157

1754_1776

1794.3333333333333

2406.0

Zinc finger

C2H2-type 3

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000429157

1782_1806

1794.3333333333333

2406.0

Zinc finger

C2H2-type 4

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000429157

192_214

1794.3333333333333

2406.0

Zinc finger

C2H2-type 1

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000429157

220_242

1794.3333333333333

2406.0

Zinc finger

C2H2-type 2

Tgene

HIVEP3

chr10:78943179

chr1:41984159

ENST00000429157

640_670

1794.3333333333333

2406.0

Zinc finger

CCHC HIVEP-type

Top

Fusion Protein-Protein Interaction

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type from validated records (BIOGRID-3.4.160)

Gene

PPI interactors

Protein-protein interactors based on sequence similarity (STRING)

Gene	STRING network
KCNMA1
HIVEP3

- Retained interactions in fusion protein (protein functional feature from UniProt).

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost interactions due to fusion (protein functional feature from UniProt).

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Related Drugs to KCNMA1-HIVEP3

Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)

Hgene

Tgene

Drug

Source

PMID

Top

Related Diseases to KCNMA1-HIVEP3

Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)

Hgene

Tgene

Disease

Source

PMID

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source