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Center for Computational Systems Medicine level2
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Fusion Gene Summary

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Fusion Gene Sample Information

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Fusion ORF Analysis

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Fusion Amino Acid Sequences

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Fusion Protein Functional Features

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Fusion Protein Structure

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pLDDT scores

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Ramachandran Plot of Fusion Protein Structure

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Fusion Protein-Protein Interaction

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Related drugs with this fusion protein

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Related disease with this fusion protein

Fusion Protein:LTBP3-LTBP1

Fusion Protein Summary

check button Fusion gene summary
Fusion partner gene informationFusion gene name: LTBP3-LTBP1
FusionPDB ID: 50288
FusionGDB2.0 ID: 50288
HgeneTgene
Gene symbol

LTBP3

LTBP1

Gene ID

4054

4052

Gene namelatent transforming growth factor beta binding protein 3latent transforming growth factor beta binding protein 1
SynonymsDASS|GPHYSD3|LTBP-3|LTBP2|STHAG6|pp6425-
Cytomap

11q13.1

2p22.3

Type of geneprotein-codingprotein-coding
Descriptionlatent-transforming growth factor beta-binding protein 3latent TGF beta binding protein 3latent-transforming growth factor beta-binding protein 1LTBP-1TGF-beta1-BP-1transforming growth factor beta-1-binding protein 1
Modification date2020032220200329
UniProtAcc

Q9NS15

Q14766

Ensembl transtripts involved in fusion geneENST idsENST00000301873, ENST00000322147, 
ENST00000529189, ENST00000530785, 
ENST00000532932, ENST00000536982, 
ENST00000498013, ENST00000272273, 
ENST00000354476, ENST00000390003, 
ENST00000402934, ENST00000404525, 
ENST00000404816, ENST00000407925, 
ENST00000418533, 
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)* DoF score9 X 12 X 4=43213 X 14 X 6=1092
# samples 1214
** MAII scorelog2(12/432*10)=-1.84799690655495
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(14/1092*10)=-2.96347412397489
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context (manual curation of fusion genes in FusionPDB)

PubMed: LTBP3 [Title/Abstract] AND LTBP1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)LTBP3(65307956)-LTBP1(33518226), # samples:2
Anticipated loss of major functional domain due to fusion event.LTBP3-LTBP1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
LTBP3-LTBP1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
LTBP3-LTBP1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
LTBP3-LTBP1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
LTBP3-LTBP1 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
LTBP3-LTBP1 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneLTBP1

GO:0035583

sequestering of TGFbeta in extracellular matrix

2022183|8617200

TgeneLTBP1

GO:1901388

regulation of transforming growth factor beta activation

2022183|8617200


check buttonFusion gene breakpoints across LTBP3 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across LTBP1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure


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Fusion Gene Sample Information

check buttonFusion gene information from FusionGDB2.0.
check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4Non-Cancer5263NLTBP3chr11

65307956

-LTBP1chr2

33518226

+
ChimerDB4Non-Cancer5373NLTBP3chr11

65307956

-LTBP1chr2

33518226

+


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Fusion ORF Analysis


check buttonFusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000322147LTBP3chr1165307956-ENST00000404816LTBP1chr233518226+59743106051591719
ENST00000322147LTBP3chr1165307956-ENST00000354476LTBP1chr233518226+61213106051591719
ENST00000322147LTBP3chr1165307956-ENST00000390003LTBP1chr233518226+61213106051591719
ENST00000322147LTBP3chr1165307956-ENST00000418533LTBP1chr233518226+59953106050331677
ENST00000322147LTBP3chr1165307956-ENST00000402934LTBP1chr233518226+59663106051531717
ENST00000322147LTBP3chr1165307956-ENST00000404525LTBP1chr233518226+61243106051591719
ENST00000322147LTBP3chr1165307956-ENST00000407925LTBP1chr233518226+59783106051591719
ENST00000301873LTBP3chr1165307956-ENST00000404816LTBP1chr233518226+624333753854281796
ENST00000301873LTBP3chr1165307956-ENST00000354476LTBP1chr233518226+639033753854281796
ENST00000301873LTBP3chr1165307956-ENST00000390003LTBP1chr233518226+639033753854281796
ENST00000301873LTBP3chr1165307956-ENST00000418533LTBP1chr233518226+626433753853021754
ENST00000301873LTBP3chr1165307956-ENST00000402934LTBP1chr233518226+623533753854221794
ENST00000301873LTBP3chr1165307956-ENST00000404525LTBP1chr233518226+639333753854281796
ENST00000301873LTBP3chr1165307956-ENST00000407925LTBP1chr233518226+624733753854281796
ENST00000532932LTBP3chr1165307956-ENST00000404816LTBP1chr233518226+5128226084643131155
ENST00000532932LTBP3chr1165307956-ENST00000354476LTBP1chr233518226+5275226084643131155
ENST00000532932LTBP3chr1165307956-ENST00000390003LTBP1chr233518226+5275226084643131155
ENST00000532932LTBP3chr1165307956-ENST00000418533LTBP1chr233518226+5149226084641871113
ENST00000532932LTBP3chr1165307956-ENST00000402934LTBP1chr233518226+5120226084643071153
ENST00000532932LTBP3chr1165307956-ENST00000404525LTBP1chr233518226+5278226084643131155
ENST00000532932LTBP3chr1165307956-ENST00000407925LTBP1chr233518226+5132226084643131155
ENST00000536982LTBP3chr1165307956-ENST00000404816LTBP1chr233518226+492520577341101345
ENST00000536982LTBP3chr1165307956-ENST00000354476LTBP1chr233518226+507220577341101345
ENST00000536982LTBP3chr1165307956-ENST00000390003LTBP1chr233518226+507220577341101345
ENST00000536982LTBP3chr1165307956-ENST00000418533LTBP1chr233518226+494620577339841303
ENST00000536982LTBP3chr1165307956-ENST00000402934LTBP1chr233518226+491720577341041343
ENST00000536982LTBP3chr1165307956-ENST00000404525LTBP1chr233518226+507520577341101345
ENST00000536982LTBP3chr1165307956-ENST00000407925LTBP1chr233518226+492920577341101345

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000322147ENST00000404816LTBP3chr1165307956-LTBP1chr233518226+0.0002201840.9997799
ENST00000322147ENST00000354476LTBP3chr1165307956-LTBP1chr233518226+0.0001759470.9998241
ENST00000322147ENST00000390003LTBP3chr1165307956-LTBP1chr233518226+0.0001759470.9998241
ENST00000322147ENST00000418533LTBP3chr1165307956-LTBP1chr233518226+0.0003156340.99968433
ENST00000322147ENST00000402934LTBP3chr1165307956-LTBP1chr233518226+0.0003199460.99968004
ENST00000322147ENST00000404525LTBP3chr1165307956-LTBP1chr233518226+0.0001745420.99982554
ENST00000322147ENST00000407925LTBP3chr1165307956-LTBP1chr233518226+0.0002163720.9997837
ENST00000301873ENST00000404816LTBP3chr1165307956-LTBP1chr233518226+0.0003004050.9996996
ENST00000301873ENST00000354476LTBP3chr1165307956-LTBP1chr233518226+0.0002417520.9997583
ENST00000301873ENST00000390003LTBP3chr1165307956-LTBP1chr233518226+0.0002417520.9997583
ENST00000301873ENST00000418533LTBP3chr1165307956-LTBP1chr233518226+0.0004303260.9995697
ENST00000301873ENST00000402934LTBP3chr1165307956-LTBP1chr233518226+0.0004330580.999567
ENST00000301873ENST00000404525LTBP3chr1165307956-LTBP1chr233518226+0.000239560.99976045
ENST00000301873ENST00000407925LTBP3chr1165307956-LTBP1chr233518226+0.0002961480.9997038
ENST00000532932ENST00000404816LTBP3chr1165307956-LTBP1chr233518226+0.0001766590.9998234
ENST00000532932ENST00000354476LTBP3chr1165307956-LTBP1chr233518226+0.0001459690.99985397
ENST00000532932ENST00000390003LTBP3chr1165307956-LTBP1chr233518226+0.0001459690.99985397
ENST00000532932ENST00000418533LTBP3chr1165307956-LTBP1chr233518226+0.0002675150.99973243
ENST00000532932ENST00000402934LTBP3chr1165307956-LTBP1chr233518226+0.0002830360.99971694
ENST00000532932ENST00000404525LTBP3chr1165307956-LTBP1chr233518226+0.0001455720.99985445
ENST00000532932ENST00000407925LTBP3chr1165307956-LTBP1chr233518226+0.0001751750.9998248
ENST00000536982ENST00000404816LTBP3chr1165307956-LTBP1chr233518226+0.0001338730.9998661
ENST00000536982ENST00000354476LTBP3chr1165307956-LTBP1chr233518226+0.0001070360.99989295
ENST00000536982ENST00000390003LTBP3chr1165307956-LTBP1chr233518226+0.0001070360.99989295
ENST00000536982ENST00000418533LTBP3chr1165307956-LTBP1chr233518226+0.0001942190.99980575
ENST00000536982ENST00000402934LTBP3chr1165307956-LTBP1chr233518226+0.000202750.9997973
ENST00000536982ENST00000404525LTBP3chr1165307956-LTBP1chr233518226+0.0001066270.9998933
ENST00000536982ENST00000407925LTBP3chr1165307956-LTBP1chr233518226+0.0001315720.9998684

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Fusion Amino Acid Sequences


check button For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

>50288_50288_1_LTBP3-LTBP1_LTBP3_chr11_65307956_ENST00000301873_LTBP1_chr2_33518226_ENST00000354476_length(amino acids)=1796AA_BP=1162
MVWASSWGWEVSALPAVQSASPRLPPGPRGPLPPASPAALPRCPLPSPGAPGPLLPSGAGPSPRPGAPPLPRVLRPRMPGPRGAAGGLAP
EMRGAGAAGLLALLLLLLLLLLGLGGRVEGGPAGERGAGGGGALARERFKVVFAPVICKRTCLKGQCRDSCQQGSNMTLIGENGHSTDTL
TGSGFRVVVCPLPCMNGGQCSSRNQCLCPPDFTGRFCQVPAGGAGGGTGGSGPGLSRTGALSTGALPPLAPEGDSVASKHAIYAVQVIAD
PPGPGEGPPAQHAAFLVPLGPGQISAEVQAPPPVVNVRVHHPPEASVQVHRIESSNAESAAPSQHLLPHPKPSHPRPPTQKPLGRCFQDT
LPKQPCGSNPLPGLTKQEDCCGSIGTAWGQSKCHKCPQLQYTGVQKPGPVRGEVGADCPQGYKRLNSTHCQDINECAMPGVCRHGDCLNN
PGSYRCVCPPGHSLGPSRTQCIADKPEEKSLCFRLVSPEHQCQHPLTTRLTRQLCCCSVGKAWGARCQRCPTDGTAAFKEICPAGKGYHI
LTSHQTLTIQGESDFSLFLHPDGPPKPQQLPESPSQAPPPEDTEEERGVTTDSPVSEERSVQQSHPTATTTPARPYPELISRPSPPTMRW
FLPDLPPSRSAVEIAPTQVTETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICMNTGGSYNCHC
NRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSSCPDGKCENKPGSFKCIACQPG
YRSQGGGACRDVNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGDVCDNGICSNTPGSFQCQCLSGYHLSRDRSH
CEDIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQP
HHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSE
ICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCK
NTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYD
CTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGF
QAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAP
NVTKQECCCTSGVGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQG
TYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQT
TYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGR

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>50288_50288_2_LTBP3-LTBP1_LTBP3_chr11_65307956_ENST00000301873_LTBP1_chr2_33518226_ENST00000390003_length(amino acids)=1796AA_BP=1162
MVWASSWGWEVSALPAVQSASPRLPPGPRGPLPPASPAALPRCPLPSPGAPGPLLPSGAGPSPRPGAPPLPRVLRPRMPGPRGAAGGLAP
EMRGAGAAGLLALLLLLLLLLLGLGGRVEGGPAGERGAGGGGALARERFKVVFAPVICKRTCLKGQCRDSCQQGSNMTLIGENGHSTDTL
TGSGFRVVVCPLPCMNGGQCSSRNQCLCPPDFTGRFCQVPAGGAGGGTGGSGPGLSRTGALSTGALPPLAPEGDSVASKHAIYAVQVIAD
PPGPGEGPPAQHAAFLVPLGPGQISAEVQAPPPVVNVRVHHPPEASVQVHRIESSNAESAAPSQHLLPHPKPSHPRPPTQKPLGRCFQDT
LPKQPCGSNPLPGLTKQEDCCGSIGTAWGQSKCHKCPQLQYTGVQKPGPVRGEVGADCPQGYKRLNSTHCQDINECAMPGVCRHGDCLNN
PGSYRCVCPPGHSLGPSRTQCIADKPEEKSLCFRLVSPEHQCQHPLTTRLTRQLCCCSVGKAWGARCQRCPTDGTAAFKEICPAGKGYHI
LTSHQTLTIQGESDFSLFLHPDGPPKPQQLPESPSQAPPPEDTEEERGVTTDSPVSEERSVQQSHPTATTTPARPYPELISRPSPPTMRW
FLPDLPPSRSAVEIAPTQVTETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICMNTGGSYNCHC
NRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSSCPDGKCENKPGSFKCIACQPG
YRSQGGGACRDVNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGDVCDNGICSNTPGSFQCQCLSGYHLSRDRSH
CEDIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQP
HHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSE
ICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCK
NTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYD
CTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGF
QAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAP
NVTKQECCCTSGVGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQG
TYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQT
TYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGR

--------------------------------------------------------------

>50288_50288_3_LTBP3-LTBP1_LTBP3_chr11_65307956_ENST00000301873_LTBP1_chr2_33518226_ENST00000402934_length(amino acids)=1794AA_BP=1162
MVWASSWGWEVSALPAVQSASPRLPPGPRGPLPPASPAALPRCPLPSPGAPGPLLPSGAGPSPRPGAPPLPRVLRPRMPGPRGAAGGLAP
EMRGAGAAGLLALLLLLLLLLLGLGGRVEGGPAGERGAGGGGALARERFKVVFAPVICKRTCLKGQCRDSCQQGSNMTLIGENGHSTDTL
TGSGFRVVVCPLPCMNGGQCSSRNQCLCPPDFTGRFCQVPAGGAGGGTGGSGPGLSRTGALSTGALPPLAPEGDSVASKHAIYAVQVIAD
PPGPGEGPPAQHAAFLVPLGPGQISAEVQAPPPVVNVRVHHPPEASVQVHRIESSNAESAAPSQHLLPHPKPSHPRPPTQKPLGRCFQDT
LPKQPCGSNPLPGLTKQEDCCGSIGTAWGQSKCHKCPQLQYTGVQKPGPVRGEVGADCPQGYKRLNSTHCQDINECAMPGVCRHGDCLNN
PGSYRCVCPPGHSLGPSRTQCIADKPEEKSLCFRLVSPEHQCQHPLTTRLTRQLCCCSVGKAWGARCQRCPTDGTAAFKEICPAGKGYHI
LTSHQTLTIQGESDFSLFLHPDGPPKPQQLPESPSQAPPPEDTEEERGVTTDSPVSEERSVQQSHPTATTTPARPYPELISRPSPPTMRW
FLPDLPPSRSAVEIAPTQVTETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICMNTGGSYNCHC
NRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSSCPDGKCENKPGSFKCIACQPG
YRSQGGGACRDVNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGDVCDNGICSNTPGSFQCQCLSGYHLSRDRSH
CEDIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQP
HHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSE
ICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCK
NTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYD
CTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGF
QAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDVDVDQPKEEKKECYYNLNDASLCDNVLAPNV
TKQECCCTSGVGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTY
YDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTY
TECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCV

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>50288_50288_4_LTBP3-LTBP1_LTBP3_chr11_65307956_ENST00000301873_LTBP1_chr2_33518226_ENST00000404525_length(amino acids)=1796AA_BP=1162
MVWASSWGWEVSALPAVQSASPRLPPGPRGPLPPASPAALPRCPLPSPGAPGPLLPSGAGPSPRPGAPPLPRVLRPRMPGPRGAAGGLAP
EMRGAGAAGLLALLLLLLLLLLGLGGRVEGGPAGERGAGGGGALARERFKVVFAPVICKRTCLKGQCRDSCQQGSNMTLIGENGHSTDTL
TGSGFRVVVCPLPCMNGGQCSSRNQCLCPPDFTGRFCQVPAGGAGGGTGGSGPGLSRTGALSTGALPPLAPEGDSVASKHAIYAVQVIAD
PPGPGEGPPAQHAAFLVPLGPGQISAEVQAPPPVVNVRVHHPPEASVQVHRIESSNAESAAPSQHLLPHPKPSHPRPPTQKPLGRCFQDT
LPKQPCGSNPLPGLTKQEDCCGSIGTAWGQSKCHKCPQLQYTGVQKPGPVRGEVGADCPQGYKRLNSTHCQDINECAMPGVCRHGDCLNN
PGSYRCVCPPGHSLGPSRTQCIADKPEEKSLCFRLVSPEHQCQHPLTTRLTRQLCCCSVGKAWGARCQRCPTDGTAAFKEICPAGKGYHI
LTSHQTLTIQGESDFSLFLHPDGPPKPQQLPESPSQAPPPEDTEEERGVTTDSPVSEERSVQQSHPTATTTPARPYPELISRPSPPTMRW
FLPDLPPSRSAVEIAPTQVTETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICMNTGGSYNCHC
NRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSSCPDGKCENKPGSFKCIACQPG
YRSQGGGACRDVNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGDVCDNGICSNTPGSFQCQCLSGYHLSRDRSH
CEDIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQP
HHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSE
ICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCK
NTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYD
CTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGF
QAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAP
NVTKQECCCTSGVGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQG
TYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQT
TYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGR

--------------------------------------------------------------

>50288_50288_5_LTBP3-LTBP1_LTBP3_chr11_65307956_ENST00000301873_LTBP1_chr2_33518226_ENST00000404816_length(amino acids)=1796AA_BP=1162
MVWASSWGWEVSALPAVQSASPRLPPGPRGPLPPASPAALPRCPLPSPGAPGPLLPSGAGPSPRPGAPPLPRVLRPRMPGPRGAAGGLAP
EMRGAGAAGLLALLLLLLLLLLGLGGRVEGGPAGERGAGGGGALARERFKVVFAPVICKRTCLKGQCRDSCQQGSNMTLIGENGHSTDTL
TGSGFRVVVCPLPCMNGGQCSSRNQCLCPPDFTGRFCQVPAGGAGGGTGGSGPGLSRTGALSTGALPPLAPEGDSVASKHAIYAVQVIAD
PPGPGEGPPAQHAAFLVPLGPGQISAEVQAPPPVVNVRVHHPPEASVQVHRIESSNAESAAPSQHLLPHPKPSHPRPPTQKPLGRCFQDT
LPKQPCGSNPLPGLTKQEDCCGSIGTAWGQSKCHKCPQLQYTGVQKPGPVRGEVGADCPQGYKRLNSTHCQDINECAMPGVCRHGDCLNN
PGSYRCVCPPGHSLGPSRTQCIADKPEEKSLCFRLVSPEHQCQHPLTTRLTRQLCCCSVGKAWGARCQRCPTDGTAAFKEICPAGKGYHI
LTSHQTLTIQGESDFSLFLHPDGPPKPQQLPESPSQAPPPEDTEEERGVTTDSPVSEERSVQQSHPTATTTPARPYPELISRPSPPTMRW
FLPDLPPSRSAVEIAPTQVTETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICMNTGGSYNCHC
NRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSSCPDGKCENKPGSFKCIACQPG
YRSQGGGACRDVNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGDVCDNGICSNTPGSFQCQCLSGYHLSRDRSH
CEDIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQP
HHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSE
ICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCK
NTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYD
CTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGF
QAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAP
NVTKQECCCTSGVGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQG
TYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQT
TYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGR

--------------------------------------------------------------

>50288_50288_6_LTBP3-LTBP1_LTBP3_chr11_65307956_ENST00000301873_LTBP1_chr2_33518226_ENST00000407925_length(amino acids)=1796AA_BP=1162
MVWASSWGWEVSALPAVQSASPRLPPGPRGPLPPASPAALPRCPLPSPGAPGPLLPSGAGPSPRPGAPPLPRVLRPRMPGPRGAAGGLAP
EMRGAGAAGLLALLLLLLLLLLGLGGRVEGGPAGERGAGGGGALARERFKVVFAPVICKRTCLKGQCRDSCQQGSNMTLIGENGHSTDTL
TGSGFRVVVCPLPCMNGGQCSSRNQCLCPPDFTGRFCQVPAGGAGGGTGGSGPGLSRTGALSTGALPPLAPEGDSVASKHAIYAVQVIAD
PPGPGEGPPAQHAAFLVPLGPGQISAEVQAPPPVVNVRVHHPPEASVQVHRIESSNAESAAPSQHLLPHPKPSHPRPPTQKPLGRCFQDT
LPKQPCGSNPLPGLTKQEDCCGSIGTAWGQSKCHKCPQLQYTGVQKPGPVRGEVGADCPQGYKRLNSTHCQDINECAMPGVCRHGDCLNN
PGSYRCVCPPGHSLGPSRTQCIADKPEEKSLCFRLVSPEHQCQHPLTTRLTRQLCCCSVGKAWGARCQRCPTDGTAAFKEICPAGKGYHI
LTSHQTLTIQGESDFSLFLHPDGPPKPQQLPESPSQAPPPEDTEEERGVTTDSPVSEERSVQQSHPTATTTPARPYPELISRPSPPTMRW
FLPDLPPSRSAVEIAPTQVTETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICMNTGGSYNCHC
NRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSSCPDGKCENKPGSFKCIACQPG
YRSQGGGACRDVNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGDVCDNGICSNTPGSFQCQCLSGYHLSRDRSH
CEDIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQP
HHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSE
ICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCK
NTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYD
CTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGF
QAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAP
NVTKQECCCTSGVGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQG
TYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQT
TYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGR

--------------------------------------------------------------

>50288_50288_7_LTBP3-LTBP1_LTBP3_chr11_65307956_ENST00000301873_LTBP1_chr2_33518226_ENST00000418533_length(amino acids)=1754AA_BP=1162
MVWASSWGWEVSALPAVQSASPRLPPGPRGPLPPASPAALPRCPLPSPGAPGPLLPSGAGPSPRPGAPPLPRVLRPRMPGPRGAAGGLAP
EMRGAGAAGLLALLLLLLLLLLGLGGRVEGGPAGERGAGGGGALARERFKVVFAPVICKRTCLKGQCRDSCQQGSNMTLIGENGHSTDTL
TGSGFRVVVCPLPCMNGGQCSSRNQCLCPPDFTGRFCQVPAGGAGGGTGGSGPGLSRTGALSTGALPPLAPEGDSVASKHAIYAVQVIAD
PPGPGEGPPAQHAAFLVPLGPGQISAEVQAPPPVVNVRVHHPPEASVQVHRIESSNAESAAPSQHLLPHPKPSHPRPPTQKPLGRCFQDT
LPKQPCGSNPLPGLTKQEDCCGSIGTAWGQSKCHKCPQLQYTGVQKPGPVRGEVGADCPQGYKRLNSTHCQDINECAMPGVCRHGDCLNN
PGSYRCVCPPGHSLGPSRTQCIADKPEEKSLCFRLVSPEHQCQHPLTTRLTRQLCCCSVGKAWGARCQRCPTDGTAAFKEICPAGKGYHI
LTSHQTLTIQGESDFSLFLHPDGPPKPQQLPESPSQAPPPEDTEEERGVTTDSPVSEERSVQQSHPTATTTPARPYPELISRPSPPTMRW
FLPDLPPSRSAVEIAPTQVTETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICMNTGGSYNCHC
NRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSSCPDGKCENKPGSFKCIACQPG
YRSQGGGACRDVNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGDVCDNGICSNTPGSFQCQCLSGYHLSRDRSH
CEDIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQP
HHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSE
ICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCK
NTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYD
CTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDVNECELLSGVCGEAFCENVEGSFLCVCADEN
QEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGVGWGDNCEIFPCPVLGTAEFTEMCPKGKGF
VPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPM
VLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQP
YGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCK

--------------------------------------------------------------

>50288_50288_8_LTBP3-LTBP1_LTBP3_chr11_65307956_ENST00000322147_LTBP1_chr2_33518226_ENST00000354476_length(amino acids)=1719AA_BP=1085
MPGPRGAAGGLAPEMRGAGAAGLLALLLLLLLLLLGLGGRVEGGPAGERGAGGGGALARERFKVVFAPVICKRTCLKGQCRDSCQQGSNM
TLIGENGHSTDTLTGSGFRVVVCPLPCMNGGQCSSRNQCLCPPDFTGRFCQVPAGGAGGGTGGSGPGLSRTGALSTGALPPLAPEGDSVA
SKHAIYAVQVIADPPGPGEGPPAQHAAFLVPLGPGQISAEVQAPPPVVNVRVHHPPEASVQVHRIESSNAESAAPSQHLLPHPKPSHPRP
PTQKPLGRCFQDTLPKQPCGSNPLPGLTKQEDCCGSIGTAWGQSKCHKCPQLQYTGVQKPGPVRGEVGADCPQGYKRLNSTHCQDINECA
MPGVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQCIADKPEEKSLCFRLVSPEHQCQHPLTTRLTRQLCCCSVGKAWGARCQRCPTDGTAA
FKEICPAGKGYHILTSHQTLTIQGESDFSLFLHPDGPPKPQQLPESPSQAPPPEDTEEERGVTTDSPVSEERSVQQSHPTATTTPARPYP
ELISRPSPPTMRWFLPDLPPSRSAVEIAPTQVTETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRG
ICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSSCPDGKCEN
KPGSFKCIACQPGYRSQGGGACRDVNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGDVCDNGICSNTPGSFQCQ
CLSGYHLSRDRSHCEDIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTP
TQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPA
HRDIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDE
CQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVC
QRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDN
TAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYN
LNDASLCDNVLAPNVTKQECCCTSGVGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCL
NTRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSD
EYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQA
EECGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCTPLNTAL

--------------------------------------------------------------

>50288_50288_9_LTBP3-LTBP1_LTBP3_chr11_65307956_ENST00000322147_LTBP1_chr2_33518226_ENST00000390003_length(amino acids)=1719AA_BP=1085
MPGPRGAAGGLAPEMRGAGAAGLLALLLLLLLLLLGLGGRVEGGPAGERGAGGGGALARERFKVVFAPVICKRTCLKGQCRDSCQQGSNM
TLIGENGHSTDTLTGSGFRVVVCPLPCMNGGQCSSRNQCLCPPDFTGRFCQVPAGGAGGGTGGSGPGLSRTGALSTGALPPLAPEGDSVA
SKHAIYAVQVIADPPGPGEGPPAQHAAFLVPLGPGQISAEVQAPPPVVNVRVHHPPEASVQVHRIESSNAESAAPSQHLLPHPKPSHPRP
PTQKPLGRCFQDTLPKQPCGSNPLPGLTKQEDCCGSIGTAWGQSKCHKCPQLQYTGVQKPGPVRGEVGADCPQGYKRLNSTHCQDINECA
MPGVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQCIADKPEEKSLCFRLVSPEHQCQHPLTTRLTRQLCCCSVGKAWGARCQRCPTDGTAA
FKEICPAGKGYHILTSHQTLTIQGESDFSLFLHPDGPPKPQQLPESPSQAPPPEDTEEERGVTTDSPVSEERSVQQSHPTATTTPARPYP
ELISRPSPPTMRWFLPDLPPSRSAVEIAPTQVTETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRG
ICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSSCPDGKCEN
KPGSFKCIACQPGYRSQGGGACRDVNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGDVCDNGICSNTPGSFQCQ
CLSGYHLSRDRSHCEDIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTP
TQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPA
HRDIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDE
CQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVC
QRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDN
TAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYN
LNDASLCDNVLAPNVTKQECCCTSGVGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCL
NTRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSD
EYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQA
EECGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCTPLNTAL

--------------------------------------------------------------

>50288_50288_10_LTBP3-LTBP1_LTBP3_chr11_65307956_ENST00000322147_LTBP1_chr2_33518226_ENST00000402934_length(amino acids)=1717AA_BP=1085
MPGPRGAAGGLAPEMRGAGAAGLLALLLLLLLLLLGLGGRVEGGPAGERGAGGGGALARERFKVVFAPVICKRTCLKGQCRDSCQQGSNM
TLIGENGHSTDTLTGSGFRVVVCPLPCMNGGQCSSRNQCLCPPDFTGRFCQVPAGGAGGGTGGSGPGLSRTGALSTGALPPLAPEGDSVA
SKHAIYAVQVIADPPGPGEGPPAQHAAFLVPLGPGQISAEVQAPPPVVNVRVHHPPEASVQVHRIESSNAESAAPSQHLLPHPKPSHPRP
PTQKPLGRCFQDTLPKQPCGSNPLPGLTKQEDCCGSIGTAWGQSKCHKCPQLQYTGVQKPGPVRGEVGADCPQGYKRLNSTHCQDINECA
MPGVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQCIADKPEEKSLCFRLVSPEHQCQHPLTTRLTRQLCCCSVGKAWGARCQRCPTDGTAA
FKEICPAGKGYHILTSHQTLTIQGESDFSLFLHPDGPPKPQQLPESPSQAPPPEDTEEERGVTTDSPVSEERSVQQSHPTATTTPARPYP
ELISRPSPPTMRWFLPDLPPSRSAVEIAPTQVTETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRG
ICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSSCPDGKCEN
KPGSFKCIACQPGYRSQGGGACRDVNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGDVCDNGICSNTPGSFQCQ
CLSGYHLSRDRSHCEDIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTP
TQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPA
HRDIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDE
CQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVC
QRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDN
TAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDVDVDQPKEEKKECYYNLN
DASLCDNVLAPNVTKQECCCTSGVGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNT
RPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEY
VCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEE
CGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCTPLNTALNL

--------------------------------------------------------------

>50288_50288_11_LTBP3-LTBP1_LTBP3_chr11_65307956_ENST00000322147_LTBP1_chr2_33518226_ENST00000404525_length(amino acids)=1719AA_BP=1085
MPGPRGAAGGLAPEMRGAGAAGLLALLLLLLLLLLGLGGRVEGGPAGERGAGGGGALARERFKVVFAPVICKRTCLKGQCRDSCQQGSNM
TLIGENGHSTDTLTGSGFRVVVCPLPCMNGGQCSSRNQCLCPPDFTGRFCQVPAGGAGGGTGGSGPGLSRTGALSTGALPPLAPEGDSVA
SKHAIYAVQVIADPPGPGEGPPAQHAAFLVPLGPGQISAEVQAPPPVVNVRVHHPPEASVQVHRIESSNAESAAPSQHLLPHPKPSHPRP
PTQKPLGRCFQDTLPKQPCGSNPLPGLTKQEDCCGSIGTAWGQSKCHKCPQLQYTGVQKPGPVRGEVGADCPQGYKRLNSTHCQDINECA
MPGVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQCIADKPEEKSLCFRLVSPEHQCQHPLTTRLTRQLCCCSVGKAWGARCQRCPTDGTAA
FKEICPAGKGYHILTSHQTLTIQGESDFSLFLHPDGPPKPQQLPESPSQAPPPEDTEEERGVTTDSPVSEERSVQQSHPTATTTPARPYP
ELISRPSPPTMRWFLPDLPPSRSAVEIAPTQVTETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRG
ICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSSCPDGKCEN
KPGSFKCIACQPGYRSQGGGACRDVNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGDVCDNGICSNTPGSFQCQ
CLSGYHLSRDRSHCEDIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTP
TQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPA
HRDIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDE
CQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVC
QRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDN
TAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYN
LNDASLCDNVLAPNVTKQECCCTSGVGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCL
NTRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSD
EYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQA
EECGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCTPLNTAL

--------------------------------------------------------------

>50288_50288_12_LTBP3-LTBP1_LTBP3_chr11_65307956_ENST00000322147_LTBP1_chr2_33518226_ENST00000404816_length(amino acids)=1719AA_BP=1085
MPGPRGAAGGLAPEMRGAGAAGLLALLLLLLLLLLGLGGRVEGGPAGERGAGGGGALARERFKVVFAPVICKRTCLKGQCRDSCQQGSNM
TLIGENGHSTDTLTGSGFRVVVCPLPCMNGGQCSSRNQCLCPPDFTGRFCQVPAGGAGGGTGGSGPGLSRTGALSTGALPPLAPEGDSVA
SKHAIYAVQVIADPPGPGEGPPAQHAAFLVPLGPGQISAEVQAPPPVVNVRVHHPPEASVQVHRIESSNAESAAPSQHLLPHPKPSHPRP
PTQKPLGRCFQDTLPKQPCGSNPLPGLTKQEDCCGSIGTAWGQSKCHKCPQLQYTGVQKPGPVRGEVGADCPQGYKRLNSTHCQDINECA
MPGVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQCIADKPEEKSLCFRLVSPEHQCQHPLTTRLTRQLCCCSVGKAWGARCQRCPTDGTAA
FKEICPAGKGYHILTSHQTLTIQGESDFSLFLHPDGPPKPQQLPESPSQAPPPEDTEEERGVTTDSPVSEERSVQQSHPTATTTPARPYP
ELISRPSPPTMRWFLPDLPPSRSAVEIAPTQVTETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRG
ICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSSCPDGKCEN
KPGSFKCIACQPGYRSQGGGACRDVNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGDVCDNGICSNTPGSFQCQ
CLSGYHLSRDRSHCEDIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTP
TQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPA
HRDIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDE
CQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVC
QRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDN
TAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYN
LNDASLCDNVLAPNVTKQECCCTSGVGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCL
NTRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSD
EYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQA
EECGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCTPLNTAL

--------------------------------------------------------------

>50288_50288_13_LTBP3-LTBP1_LTBP3_chr11_65307956_ENST00000322147_LTBP1_chr2_33518226_ENST00000407925_length(amino acids)=1719AA_BP=1085
MPGPRGAAGGLAPEMRGAGAAGLLALLLLLLLLLLGLGGRVEGGPAGERGAGGGGALARERFKVVFAPVICKRTCLKGQCRDSCQQGSNM
TLIGENGHSTDTLTGSGFRVVVCPLPCMNGGQCSSRNQCLCPPDFTGRFCQVPAGGAGGGTGGSGPGLSRTGALSTGALPPLAPEGDSVA
SKHAIYAVQVIADPPGPGEGPPAQHAAFLVPLGPGQISAEVQAPPPVVNVRVHHPPEASVQVHRIESSNAESAAPSQHLLPHPKPSHPRP
PTQKPLGRCFQDTLPKQPCGSNPLPGLTKQEDCCGSIGTAWGQSKCHKCPQLQYTGVQKPGPVRGEVGADCPQGYKRLNSTHCQDINECA
MPGVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQCIADKPEEKSLCFRLVSPEHQCQHPLTTRLTRQLCCCSVGKAWGARCQRCPTDGTAA
FKEICPAGKGYHILTSHQTLTIQGESDFSLFLHPDGPPKPQQLPESPSQAPPPEDTEEERGVTTDSPVSEERSVQQSHPTATTTPARPYP
ELISRPSPPTMRWFLPDLPPSRSAVEIAPTQVTETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRG
ICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSSCPDGKCEN
KPGSFKCIACQPGYRSQGGGACRDVNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGDVCDNGICSNTPGSFQCQ
CLSGYHLSRDRSHCEDIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTP
TQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPA
HRDIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDE
CQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVC
QRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDN
TAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYN
LNDASLCDNVLAPNVTKQECCCTSGVGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCL
NTRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSD
EYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQA
EECGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCTPLNTAL

--------------------------------------------------------------

>50288_50288_14_LTBP3-LTBP1_LTBP3_chr11_65307956_ENST00000322147_LTBP1_chr2_33518226_ENST00000418533_length(amino acids)=1677AA_BP=1085
MPGPRGAAGGLAPEMRGAGAAGLLALLLLLLLLLLGLGGRVEGGPAGERGAGGGGALARERFKVVFAPVICKRTCLKGQCRDSCQQGSNM
TLIGENGHSTDTLTGSGFRVVVCPLPCMNGGQCSSRNQCLCPPDFTGRFCQVPAGGAGGGTGGSGPGLSRTGALSTGALPPLAPEGDSVA
SKHAIYAVQVIADPPGPGEGPPAQHAAFLVPLGPGQISAEVQAPPPVVNVRVHHPPEASVQVHRIESSNAESAAPSQHLLPHPKPSHPRP
PTQKPLGRCFQDTLPKQPCGSNPLPGLTKQEDCCGSIGTAWGQSKCHKCPQLQYTGVQKPGPVRGEVGADCPQGYKRLNSTHCQDINECA
MPGVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQCIADKPEEKSLCFRLVSPEHQCQHPLTTRLTRQLCCCSVGKAWGARCQRCPTDGTAA
FKEICPAGKGYHILTSHQTLTIQGESDFSLFLHPDGPPKPQQLPESPSQAPPPEDTEEERGVTTDSPVSEERSVQQSHPTATTTPARPYP
ELISRPSPPTMRWFLPDLPPSRSAVEIAPTQVTETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRG
ICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSSCPDGKCEN
KPGSFKCIACQPGYRSQGGGACRDVNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGDVCDNGICSNTPGSFQCQ
CLSGYHLSRDRSHCEDIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTP
TQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPA
HRDIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDE
CQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVC
QRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDVNECELLSGVCGEAFCEN
VEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGVGWGDNCEIFPCPVLGT
AEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCVN
TEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYA
QLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVN

--------------------------------------------------------------

>50288_50288_15_LTBP3-LTBP1_LTBP3_chr11_65307956_ENST00000532932_LTBP1_chr2_33518226_ENST00000354476_length(amino acids)=1155AA_BP=521
MPLDLAMPAETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICMNTGGSYNCHCNRGYRLHVGAG
GRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSSCPDGKCENKPGSFKCIACQPGYRSQGGGACRD
VNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGDVCDNGICSNTPGSFQCQCLSGYHLSRDRSHCEDIDECDFPA
ACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKECYLNFD
DTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEICKEGKCVNTQ
PGYECYCKQGFYYDGNLLECVDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCG
QGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDD
NKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVD
VNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTS
GVGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCF
DMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGE
AWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCVRVQEGYTCD

--------------------------------------------------------------

>50288_50288_16_LTBP3-LTBP1_LTBP3_chr11_65307956_ENST00000532932_LTBP1_chr2_33518226_ENST00000390003_length(amino acids)=1155AA_BP=521
MPLDLAMPAETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICMNTGGSYNCHCNRGYRLHVGAG
GRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSSCPDGKCENKPGSFKCIACQPGYRSQGGGACRD
VNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGDVCDNGICSNTPGSFQCQCLSGYHLSRDRSHCEDIDECDFPA
ACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKECYLNFD
DTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEICKEGKCVNTQ
PGYECYCKQGFYYDGNLLECVDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCG
QGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDD
NKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVD
VNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTS
GVGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCF
DMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGE
AWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCVRVQEGYTCD

--------------------------------------------------------------

>50288_50288_17_LTBP3-LTBP1_LTBP3_chr11_65307956_ENST00000532932_LTBP1_chr2_33518226_ENST00000402934_length(amino acids)=1153AA_BP=521
MPLDLAMPAETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICMNTGGSYNCHCNRGYRLHVGAG
GRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSSCPDGKCENKPGSFKCIACQPGYRSQGGGACRD
VNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGDVCDNGICSNTPGSFQCQCLSGYHLSRDRSHCEDIDECDFPA
ACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKECYLNFD
DTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEICKEGKCVNTQ
PGYECYCKQGFYYDGNLLECVDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCG
QGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDD
NKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVD
VNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGV
GWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDM
DECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAW
GMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCVRVQEGYTCDCF

--------------------------------------------------------------

>50288_50288_18_LTBP3-LTBP1_LTBP3_chr11_65307956_ENST00000532932_LTBP1_chr2_33518226_ENST00000404525_length(amino acids)=1155AA_BP=521
MPLDLAMPAETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICMNTGGSYNCHCNRGYRLHVGAG
GRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSSCPDGKCENKPGSFKCIACQPGYRSQGGGACRD
VNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGDVCDNGICSNTPGSFQCQCLSGYHLSRDRSHCEDIDECDFPA
ACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKECYLNFD
DTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEICKEGKCVNTQ
PGYECYCKQGFYYDGNLLECVDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCG
QGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDD
NKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVD
VNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTS
GVGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCF
DMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGE
AWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCVRVQEGYTCD

--------------------------------------------------------------

>50288_50288_19_LTBP3-LTBP1_LTBP3_chr11_65307956_ENST00000532932_LTBP1_chr2_33518226_ENST00000404816_length(amino acids)=1155AA_BP=521
MPLDLAMPAETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICMNTGGSYNCHCNRGYRLHVGAG
GRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSSCPDGKCENKPGSFKCIACQPGYRSQGGGACRD
VNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGDVCDNGICSNTPGSFQCQCLSGYHLSRDRSHCEDIDECDFPA
ACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKECYLNFD
DTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEICKEGKCVNTQ
PGYECYCKQGFYYDGNLLECVDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCG
QGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDD
NKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVD
VNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTS
GVGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCF
DMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGE
AWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCVRVQEGYTCD

--------------------------------------------------------------

>50288_50288_20_LTBP3-LTBP1_LTBP3_chr11_65307956_ENST00000532932_LTBP1_chr2_33518226_ENST00000407925_length(amino acids)=1155AA_BP=521
MPLDLAMPAETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICMNTGGSYNCHCNRGYRLHVGAG
GRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSSCPDGKCENKPGSFKCIACQPGYRSQGGGACRD
VNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGDVCDNGICSNTPGSFQCQCLSGYHLSRDRSHCEDIDECDFPA
ACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKECYLNFD
DTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEICKEGKCVNTQ
PGYECYCKQGFYYDGNLLECVDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCG
QGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDD
NKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVD
VNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTS
GVGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCF
DMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGE
AWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCVRVQEGYTCD

--------------------------------------------------------------

>50288_50288_21_LTBP3-LTBP1_LTBP3_chr11_65307956_ENST00000532932_LTBP1_chr2_33518226_ENST00000418533_length(amino acids)=1113AA_BP=521
MPLDLAMPAETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICMNTGGSYNCHCNRGYRLHVGAG
GRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSSCPDGKCENKPGSFKCIACQPGYRSQGGGACRD
VNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGDVCDNGICSNTPGSFQCQCLSGYHLSRDRSHCEDIDECDFPA
ACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKECYLNFD
DTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEICKEGKCVNTQ
PGYECYCKQGFYYDGNLLECVDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCG
QGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDD
NKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCR
SRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGVGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAG
GENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIR
PAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSE
QYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSY

--------------------------------------------------------------

>50288_50288_22_LTBP3-LTBP1_LTBP3_chr11_65307956_ENST00000536982_LTBP1_chr2_33518226_ENST00000354476_length(amino acids)=1345AA_BP=711
MTLIGENGHSTDTLTGSGFRVADKPEEKSLCFRLVSPEHQCQHPLTTRLTRQLCCCSVGKAWGARCQRCPTDGTAAFKEICPAGKGYHIL
TSHQTLTIQGESDFSLFLHPDGPPKPQQLPESPSQAPPPEDTEEERGVTTDSPVSEERSVQQSHPTATTTPARPYPELISRPSPPTMRWF
LPDLPPSRSAVEIAPTQVTETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICMNTGGSYNCHCN
RGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSSCPDGKCENKPGSFKCIACQPGY
RSQGGGACRDVNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGDVCDNGICSNTPGSFQCQCLSGYHLSRDRSHC
EDIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPH
HKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEI
CKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKN
TEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDC
TCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQ
APQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPN
VTKQECCCTSGVGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGT
YYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTT
YTECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRC

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>50288_50288_23_LTBP3-LTBP1_LTBP3_chr11_65307956_ENST00000536982_LTBP1_chr2_33518226_ENST00000390003_length(amino acids)=1345AA_BP=711
MTLIGENGHSTDTLTGSGFRVADKPEEKSLCFRLVSPEHQCQHPLTTRLTRQLCCCSVGKAWGARCQRCPTDGTAAFKEICPAGKGYHIL
TSHQTLTIQGESDFSLFLHPDGPPKPQQLPESPSQAPPPEDTEEERGVTTDSPVSEERSVQQSHPTATTTPARPYPELISRPSPPTMRWF
LPDLPPSRSAVEIAPTQVTETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICMNTGGSYNCHCN
RGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSSCPDGKCENKPGSFKCIACQPGY
RSQGGGACRDVNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGDVCDNGICSNTPGSFQCQCLSGYHLSRDRSHC
EDIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPH
HKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEI
CKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKN
TEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDC
TCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQ
APQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPN
VTKQECCCTSGVGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGT
YYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTT
YTECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRC

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>50288_50288_24_LTBP3-LTBP1_LTBP3_chr11_65307956_ENST00000536982_LTBP1_chr2_33518226_ENST00000402934_length(amino acids)=1343AA_BP=711
MTLIGENGHSTDTLTGSGFRVADKPEEKSLCFRLVSPEHQCQHPLTTRLTRQLCCCSVGKAWGARCQRCPTDGTAAFKEICPAGKGYHIL
TSHQTLTIQGESDFSLFLHPDGPPKPQQLPESPSQAPPPEDTEEERGVTTDSPVSEERSVQQSHPTATTTPARPYPELISRPSPPTMRWF
LPDLPPSRSAVEIAPTQVTETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICMNTGGSYNCHCN
RGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSSCPDGKCENKPGSFKCIACQPGY
RSQGGGACRDVNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGDVCDNGICSNTPGSFQCQCLSGYHLSRDRSHC
EDIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPH
HKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEI
CKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKN
TEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDC
TCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQ
APQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVT
KQECCCTSGVGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYY
DPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYT
ECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCVR

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>50288_50288_25_LTBP3-LTBP1_LTBP3_chr11_65307956_ENST00000536982_LTBP1_chr2_33518226_ENST00000404525_length(amino acids)=1345AA_BP=711
MTLIGENGHSTDTLTGSGFRVADKPEEKSLCFRLVSPEHQCQHPLTTRLTRQLCCCSVGKAWGARCQRCPTDGTAAFKEICPAGKGYHIL
TSHQTLTIQGESDFSLFLHPDGPPKPQQLPESPSQAPPPEDTEEERGVTTDSPVSEERSVQQSHPTATTTPARPYPELISRPSPPTMRWF
LPDLPPSRSAVEIAPTQVTETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICMNTGGSYNCHCN
RGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSSCPDGKCENKPGSFKCIACQPGY
RSQGGGACRDVNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGDVCDNGICSNTPGSFQCQCLSGYHLSRDRSHC
EDIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPH
HKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEI
CKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKN
TEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDC
TCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQ
APQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPN
VTKQECCCTSGVGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGT
YYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTT
YTECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRC

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>50288_50288_26_LTBP3-LTBP1_LTBP3_chr11_65307956_ENST00000536982_LTBP1_chr2_33518226_ENST00000404816_length(amino acids)=1345AA_BP=711
MTLIGENGHSTDTLTGSGFRVADKPEEKSLCFRLVSPEHQCQHPLTTRLTRQLCCCSVGKAWGARCQRCPTDGTAAFKEICPAGKGYHIL
TSHQTLTIQGESDFSLFLHPDGPPKPQQLPESPSQAPPPEDTEEERGVTTDSPVSEERSVQQSHPTATTTPARPYPELISRPSPPTMRWF
LPDLPPSRSAVEIAPTQVTETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICMNTGGSYNCHCN
RGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSSCPDGKCENKPGSFKCIACQPGY
RSQGGGACRDVNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGDVCDNGICSNTPGSFQCQCLSGYHLSRDRSHC
EDIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPH
HKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEI
CKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKN
TEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDC
TCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQ
APQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPN
VTKQECCCTSGVGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGT
YYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTT
YTECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRC

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>50288_50288_27_LTBP3-LTBP1_LTBP3_chr11_65307956_ENST00000536982_LTBP1_chr2_33518226_ENST00000407925_length(amino acids)=1345AA_BP=711
MTLIGENGHSTDTLTGSGFRVADKPEEKSLCFRLVSPEHQCQHPLTTRLTRQLCCCSVGKAWGARCQRCPTDGTAAFKEICPAGKGYHIL
TSHQTLTIQGESDFSLFLHPDGPPKPQQLPESPSQAPPPEDTEEERGVTTDSPVSEERSVQQSHPTATTTPARPYPELISRPSPPTMRWF
LPDLPPSRSAVEIAPTQVTETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICMNTGGSYNCHCN
RGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSSCPDGKCENKPGSFKCIACQPGY
RSQGGGACRDVNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGDVCDNGICSNTPGSFQCQCLSGYHLSRDRSHC
EDIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPH
HKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEI
CKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKN
TEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDC
TCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQ
APQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPN
VTKQECCCTSGVGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGT
YYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTT
YTECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRC

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>50288_50288_28_LTBP3-LTBP1_LTBP3_chr11_65307956_ENST00000536982_LTBP1_chr2_33518226_ENST00000418533_length(amino acids)=1303AA_BP=711
MTLIGENGHSTDTLTGSGFRVADKPEEKSLCFRLVSPEHQCQHPLTTRLTRQLCCCSVGKAWGARCQRCPTDGTAAFKEICPAGKGYHIL
TSHQTLTIQGESDFSLFLHPDGPPKPQQLPESPSQAPPPEDTEEERGVTTDSPVSEERSVQQSHPTATTTPARPYPELISRPSPPTMRWF
LPDLPPSRSAVEIAPTQVTETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICMNTGGSYNCHCN
RGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSSCPDGKCENKPGSFKCIACQPGY
RSQGGGACRDVNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGDVCDNGICSNTPGSFQCQCLSGYHLSRDRSHC
EDIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPH
HKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEI
CKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKN
TEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDC
TCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDVNECELLSGVCGEAFCENVEGSFLCVCADENQ
EYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGVGWGDNCEIFPCPVLGTAEFTEMCPKGKGFV
PAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMV
LDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPY
GRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKN

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Fusion Protein Functional Features


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr11:65307956/chr2:33518226)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
LTBP3

Q9NS15

LTBP1

Q14766

FUNCTION: Key regulator of transforming growth factor beta (TGFB1, TGFB2 and TGFB3) that controls TGF-beta activation by maintaining it in a latent state during storage in extracellular space. Associates specifically via disulfide bonds with the Latency-associated peptide (LAP), which is the regulatory chain of TGF-beta, and regulates integrin-dependent activation of TGF-beta. {ECO:0000303|PubMed:10743502, ECO:0000303|PubMed:11104663}.FUNCTION: Key regulator of transforming growth factor beta (TGFB1, TGFB2 and TGFB3) that controls TGF-beta activation by maintaining it in a latent state during storage in extracellular space (PubMed:2022183, PubMed:8617200, PubMed:8939931). Associates specifically via disulfide bonds with the Latency-associated peptide (LAP), which is the regulatory chain of TGF-beta, and regulates integrin-dependent activation of TGF-beta (PubMed:8617200, PubMed:8939931, PubMed:15184403). Outcompeted by LRRC32/GARP for binding to LAP regulatory chain of TGF-beta (PubMed:22278742). {ECO:0000269|PubMed:15184403, ECO:0000269|PubMed:2022183, ECO:0000269|PubMed:22278742, ECO:0000269|PubMed:8617200, ECO:0000269|PubMed:8939931}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

* Minus value of BPloci means that the break pointn is located before the CDS.
- Retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneLTBP3chr11:65307956chr2:33518226ENST00000301873-22283_1671035.33333333333331304.0Compositional biasNote=Gly-rich
HgeneLTBP3chr11:65307956chr2:33518226ENST00000301873-2228578_8941035.33333333333331304.0Compositional biasNote=Cys-rich
HgeneLTBP3chr11:65307956chr2:33518226ENST00000322147-22273_1671035.33333333333331257.0Compositional biasNote=Gly-rich
HgeneLTBP3chr11:65307956chr2:33518226ENST00000322147-2227578_8941035.33333333333331257.0Compositional biasNote=Cys-rich
HgeneLTBP3chr11:65307956chr2:33518226ENST00000301873-2228109_1411035.33333333333331304.0DomainEGF-like 1
HgeneLTBP3chr11:65307956chr2:33518226ENST00000301873-2228277_3311035.33333333333331304.0DomainTB 1
HgeneLTBP3chr11:65307956chr2:33518226ENST00000301873-2228355_3951035.33333333333331304.0DomainEGF-like 2%3B calcium-binding
HgeneLTBP3chr11:65307956chr2:33518226ENST00000301873-2228403_4551035.33333333333331304.0DomainTB 2
HgeneLTBP3chr11:65307956chr2:33518226ENST00000301873-2228574_6151035.33333333333331304.0DomainEGF-like 3
HgeneLTBP3chr11:65307956chr2:33518226ENST00000301873-2228616_6591035.33333333333331304.0DomainEGF-like 4%3B calcium-binding
HgeneLTBP3chr11:65307956chr2:33518226ENST00000301873-2228660_7021035.33333333333331304.0DomainEGF-like 5%3B calcium-binding
HgeneLTBP3chr11:65307956chr2:33518226ENST00000301873-2228744_7841035.33333333333331304.0DomainEGF-like 6%3B calcium-binding
HgeneLTBP3chr11:65307956chr2:33518226ENST00000301873-2228785_8251035.33333333333331304.0DomainEGF-like 7%3B calcium-binding
HgeneLTBP3chr11:65307956chr2:33518226ENST00000301873-2228826_8651035.33333333333331304.0DomainEGF-like 8%3B calcium-binding
HgeneLTBP3chr11:65307956chr2:33518226ENST00000301873-2228866_9081035.33333333333331304.0DomainEGF-like 9%3B calcium-binding
HgeneLTBP3chr11:65307956chr2:33518226ENST00000301873-2228917_9711035.33333333333331304.0DomainTB 3
HgeneLTBP3chr11:65307956chr2:33518226ENST00000301873-2228993_10351035.33333333333331304.0DomainEGF-like 10%3B calcium-binding
HgeneLTBP3chr11:65307956chr2:33518226ENST00000322147-2227109_1411035.33333333333331257.0DomainEGF-like 1
HgeneLTBP3chr11:65307956chr2:33518226ENST00000322147-2227277_3311035.33333333333331257.0DomainTB 1
HgeneLTBP3chr11:65307956chr2:33518226ENST00000322147-2227355_3951035.33333333333331257.0DomainEGF-like 2%3B calcium-binding
HgeneLTBP3chr11:65307956chr2:33518226ENST00000322147-2227403_4551035.33333333333331257.0DomainTB 2
HgeneLTBP3chr11:65307956chr2:33518226ENST00000322147-2227574_6151035.33333333333331257.0DomainEGF-like 3
HgeneLTBP3chr11:65307956chr2:33518226ENST00000322147-2227616_6591035.33333333333331257.0DomainEGF-like 4%3B calcium-binding
HgeneLTBP3chr11:65307956chr2:33518226ENST00000322147-2227660_7021035.33333333333331257.0DomainEGF-like 5%3B calcium-binding
HgeneLTBP3chr11:65307956chr2:33518226ENST00000322147-2227744_7841035.33333333333331257.0DomainEGF-like 6%3B calcium-binding
HgeneLTBP3chr11:65307956chr2:33518226ENST00000322147-2227785_8251035.33333333333331257.0DomainEGF-like 7%3B calcium-binding
HgeneLTBP3chr11:65307956chr2:33518226ENST00000322147-2227826_8651035.33333333333331257.0DomainEGF-like 8%3B calcium-binding
HgeneLTBP3chr11:65307956chr2:33518226ENST00000322147-2227866_9081035.33333333333331257.0DomainEGF-like 9%3B calcium-binding
HgeneLTBP3chr11:65307956chr2:33518226ENST00000322147-2227917_9711035.33333333333331257.0DomainTB 3
HgeneLTBP3chr11:65307956chr2:33518226ENST00000322147-2227993_10351035.33333333333331257.0DomainEGF-like 10%3B calcium-binding
TgeneLTBP1chr11:65307956chr2:33518226ENST0000035447618341038_10781038.33333333333331723.0DomainEGF-like 8%3B calcium-binding
TgeneLTBP1chr11:65307956chr2:33518226ENST0000035447618341079_11191038.33333333333331723.0DomainEGF-like 9%3B calcium-binding
TgeneLTBP1chr11:65307956chr2:33518226ENST0000035447618341120_11601038.33333333333331723.0DomainEGF-like 10%3B calcium-binding
TgeneLTBP1chr11:65307956chr2:33518226ENST0000035447618341161_12011038.33333333333331723.0DomainEGF-like 11%3B calcium-binding
TgeneLTBP1chr11:65307956chr2:33518226ENST0000035447618341202_12431038.33333333333331723.0DomainEGF-like 12%3B calcium-binding
TgeneLTBP1chr11:65307956chr2:33518226ENST0000035447618341244_12811038.33333333333331723.0DomainEGF-like 13%3B calcium-binding
TgeneLTBP1chr11:65307956chr2:33518226ENST0000035447618341286_13281038.33333333333331723.0DomainEGF-like 14%3B calcium-binding
TgeneLTBP1chr11:65307956chr2:33518226ENST0000035447618341347_14011038.33333333333331723.0DomainTB 3
TgeneLTBP1chr11:65307956chr2:33518226ENST0000035447618341424_14661038.33333333333331723.0DomainEGF-like 15%3B calcium-binding
TgeneLTBP1chr11:65307956chr2:33518226ENST0000035447618341467_15031038.33333333333331723.0DomainEGF-like 16%3B calcium-binding
TgeneLTBP1chr11:65307956chr2:33518226ENST0000035447618341524_15771038.33333333333331723.0DomainTB 4
TgeneLTBP1chr11:65307956chr2:33518226ENST0000035447618341621_16571038.33333333333331723.0DomainEGF-like 17
TgeneLTBP1chr11:65307956chr2:33518226ENST0000035447618341662_17061038.33333333333331723.0DomainEGF-like 18%3B calcium-binding
TgeneLTBP1chr11:65307956chr2:33518226ENST0000039000314301038_1078712.33333333333341397.0DomainEGF-like 8%3B calcium-binding
TgeneLTBP1chr11:65307956chr2:33518226ENST0000039000314301079_1119712.33333333333341397.0DomainEGF-like 9%3B calcium-binding
TgeneLTBP1chr11:65307956chr2:33518226ENST0000039000314301120_1160712.33333333333341397.0DomainEGF-like 10%3B calcium-binding
TgeneLTBP1chr11:65307956chr2:33518226ENST0000039000314301161_1201712.33333333333341397.0DomainEGF-like 11%3B calcium-binding
TgeneLTBP1chr11:65307956chr2:33518226ENST0000039000314301202_1243712.33333333333341397.0DomainEGF-like 12%3B calcium-binding
TgeneLTBP1chr11:65307956chr2:33518226ENST0000039000314301244_1281712.33333333333341397.0DomainEGF-like 13%3B calcium-binding
TgeneLTBP1chr11:65307956chr2:33518226ENST0000039000314301286_1328712.33333333333341397.0DomainEGF-like 14%3B calcium-binding
TgeneLTBP1chr11:65307956chr2:33518226ENST0000039000314301347_1401712.33333333333341397.0DomainTB 3
TgeneLTBP1chr11:65307956chr2:33518226ENST0000039000314301424_1466712.33333333333341397.0DomainEGF-like 15%3B calcium-binding
TgeneLTBP1chr11:65307956chr2:33518226ENST0000039000314301467_1503712.33333333333341397.0DomainEGF-like 16%3B calcium-binding
TgeneLTBP1chr11:65307956chr2:33518226ENST0000039000314301524_1577712.33333333333341397.0DomainTB 4
TgeneLTBP1chr11:65307956chr2:33518226ENST0000039000314301621_1657712.33333333333341397.0DomainEGF-like 17
TgeneLTBP1chr11:65307956chr2:33518226ENST0000039000314301662_1706712.33333333333341397.0DomainEGF-like 18%3B calcium-binding
TgeneLTBP1chr11:65307956chr2:33518226ENST000003900031430873_910712.33333333333341397.0DomainEGF-like 4%3B calcium-binding
TgeneLTBP1chr11:65307956chr2:33518226ENST000003900031430915_956712.33333333333341397.0DomainEGF-like 5%3B calcium-binding
TgeneLTBP1chr11:65307956chr2:33518226ENST000003900031430957_997712.33333333333341397.0DomainEGF-like 6%3B calcium-binding
TgeneLTBP1chr11:65307956chr2:33518226ENST000003900031430998_1037712.33333333333341397.0DomainEGF-like 7%3B calcium-binding
TgeneLTBP1chr11:65307956chr2:33518226ENST0000040452514301038_1078658.33333333333341343.0DomainEGF-like 8%3B calcium-binding
TgeneLTBP1chr11:65307956chr2:33518226ENST0000040452514301079_1119658.33333333333341343.0DomainEGF-like 9%3B calcium-binding
TgeneLTBP1chr11:65307956chr2:33518226ENST0000040452514301120_1160658.33333333333341343.0DomainEGF-like 10%3B calcium-binding
TgeneLTBP1chr11:65307956chr2:33518226ENST0000040452514301161_1201658.33333333333341343.0DomainEGF-like 11%3B calcium-binding
TgeneLTBP1chr11:65307956chr2:33518226ENST0000040452514301202_1243658.33333333333341343.0DomainEGF-like 12%3B calcium-binding
TgeneLTBP1chr11:65307956chr2:33518226ENST0000040452514301244_1281658.33333333333341343.0DomainEGF-like 13%3B calcium-binding
TgeneLTBP1chr11:65307956chr2:33518226ENST0000040452514301286_1328658.33333333333341343.0DomainEGF-like 14%3B calcium-binding
TgeneLTBP1chr11:65307956chr2:33518226ENST0000040452514301347_1401658.33333333333341343.0DomainTB 3
TgeneLTBP1chr11:65307956chr2:33518226ENST0000040452514301424_1466658.33333333333341343.0DomainEGF-like 15%3B calcium-binding
TgeneLTBP1chr11:65307956chr2:33518226ENST0000040452514301467_1503658.33333333333341343.0DomainEGF-like 16%3B calcium-binding
TgeneLTBP1chr11:65307956chr2:33518226ENST0000040452514301524_1577658.33333333333341343.0DomainTB 4
TgeneLTBP1chr11:65307956chr2:33518226ENST0000040452514301621_1657658.33333333333341343.0DomainEGF-like 17
TgeneLTBP1chr11:65307956chr2:33518226ENST0000040452514301662_1706658.33333333333341343.0DomainEGF-like 18%3B calcium-binding
TgeneLTBP1chr11:65307956chr2:33518226ENST000004045251430677_729658.33333333333341343.0DomainTB 2
TgeneLTBP1chr11:65307956chr2:33518226ENST000004045251430873_910658.33333333333341343.0DomainEGF-like 4%3B calcium-binding
TgeneLTBP1chr11:65307956chr2:33518226ENST000004045251430915_956658.33333333333341343.0DomainEGF-like 5%3B calcium-binding
TgeneLTBP1chr11:65307956chr2:33518226ENST000004045251430957_997658.33333333333341343.0DomainEGF-like 6%3B calcium-binding
TgeneLTBP1chr11:65307956chr2:33518226ENST000004045251430998_1037658.33333333333341343.0DomainEGF-like 7%3B calcium-binding
TgeneLTBP1chr11:65307956chr2:33518226ENST0000040481618341038_10781037.33333333333331722.0DomainEGF-like 8%3B calcium-binding
TgeneLTBP1chr11:65307956chr2:33518226ENST0000040481618341079_11191037.33333333333331722.0DomainEGF-like 9%3B calcium-binding
TgeneLTBP1chr11:65307956chr2:33518226ENST0000040481618341120_11601037.33333333333331722.0DomainEGF-like 10%3B calcium-binding
TgeneLTBP1chr11:65307956chr2:33518226ENST0000040481618341161_12011037.33333333333331722.0DomainEGF-like 11%3B calcium-binding
TgeneLTBP1chr11:65307956chr2:33518226ENST0000040481618341202_12431037.33333333333331722.0DomainEGF-like 12%3B calcium-binding
TgeneLTBP1chr11:65307956chr2:33518226ENST0000040481618341244_12811037.33333333333331722.0DomainEGF-like 13%3B calcium-binding
TgeneLTBP1chr11:65307956chr2:33518226ENST0000040481618341286_13281037.33333333333331722.0DomainEGF-like 14%3B calcium-binding
TgeneLTBP1chr11:65307956chr2:33518226ENST0000040481618341347_14011037.33333333333331722.0DomainTB 3
TgeneLTBP1chr11:65307956chr2:33518226ENST0000040481618341424_14661037.33333333333331722.0DomainEGF-like 15%3B calcium-binding
TgeneLTBP1chr11:65307956chr2:33518226ENST0000040481618341467_15031037.33333333333331722.0DomainEGF-like 16%3B calcium-binding
TgeneLTBP1chr11:65307956chr2:33518226ENST0000040481618341524_15771037.33333333333331722.0DomainTB 4
TgeneLTBP1chr11:65307956chr2:33518226ENST0000040481618341621_16571037.33333333333331722.0DomainEGF-like 17
TgeneLTBP1chr11:65307956chr2:33518226ENST0000040481618341662_17061037.33333333333331722.0DomainEGF-like 18%3B calcium-binding
TgeneLTBP1chr11:65307956chr2:33518226ENST0000040792514301038_1078711.33333333333341396.0DomainEGF-like 8%3B calcium-binding
TgeneLTBP1chr11:65307956chr2:33518226ENST0000040792514301079_1119711.33333333333341396.0DomainEGF-like 9%3B calcium-binding
TgeneLTBP1chr11:65307956chr2:33518226ENST0000040792514301120_1160711.33333333333341396.0DomainEGF-like 10%3B calcium-binding
TgeneLTBP1chr11:65307956chr2:33518226ENST0000040792514301161_1201711.33333333333341396.0DomainEGF-like 11%3B calcium-binding
TgeneLTBP1chr11:65307956chr2:33518226ENST0000040792514301202_1243711.33333333333341396.0DomainEGF-like 12%3B calcium-binding
TgeneLTBP1chr11:65307956chr2:33518226ENST0000040792514301244_1281711.33333333333341396.0DomainEGF-like 13%3B calcium-binding
TgeneLTBP1chr11:65307956chr2:33518226ENST0000040792514301286_1328711.33333333333341396.0DomainEGF-like 14%3B calcium-binding
TgeneLTBP1chr11:65307956chr2:33518226ENST0000040792514301347_1401711.33333333333341396.0DomainTB 3
TgeneLTBP1chr11:65307956chr2:33518226ENST0000040792514301424_1466711.33333333333341396.0DomainEGF-like 15%3B calcium-binding
TgeneLTBP1chr11:65307956chr2:33518226ENST0000040792514301467_1503711.33333333333341396.0DomainEGF-like 16%3B calcium-binding
TgeneLTBP1chr11:65307956chr2:33518226ENST0000040792514301524_1577711.33333333333341396.0DomainTB 4
TgeneLTBP1chr11:65307956chr2:33518226ENST0000040792514301621_1657711.33333333333341396.0DomainEGF-like 17
TgeneLTBP1chr11:65307956chr2:33518226ENST0000040792514301662_1706711.33333333333341396.0DomainEGF-like 18%3B calcium-binding
TgeneLTBP1chr11:65307956chr2:33518226ENST000004079251430873_910711.33333333333341396.0DomainEGF-like 4%3B calcium-binding
TgeneLTBP1chr11:65307956chr2:33518226ENST000004079251430915_956711.33333333333341396.0DomainEGF-like 5%3B calcium-binding
TgeneLTBP1chr11:65307956chr2:33518226ENST000004079251430957_997711.33333333333341396.0DomainEGF-like 6%3B calcium-binding
TgeneLTBP1chr11:65307956chr2:33518226ENST000004079251430998_1037711.33333333333341396.0DomainEGF-like 7%3B calcium-binding
TgeneLTBP1chr11:65307956chr2:33518226ENST0000035447618341174_11761038.33333333333331723.0MotifCell attachment site
TgeneLTBP1chr11:65307956chr2:33518226ENST0000039000314301174_1176712.33333333333341397.0MotifCell attachment site
TgeneLTBP1chr11:65307956chr2:33518226ENST0000040452514301174_1176658.33333333333341343.0MotifCell attachment site
TgeneLTBP1chr11:65307956chr2:33518226ENST0000040481618341174_11761037.33333333333331722.0MotifCell attachment site
TgeneLTBP1chr11:65307956chr2:33518226ENST0000040792514301174_1176711.33333333333341396.0MotifCell attachment site
TgeneLTBP1chr11:65307956chr2:33518226ENST0000035447618341344_14111038.33333333333331723.0Region8-Cys3 region
TgeneLTBP1chr11:65307956chr2:33518226ENST0000035447618341507_17211038.33333333333331723.0RegionC-terminal domain
TgeneLTBP1chr11:65307956chr2:33518226ENST0000039000314301344_1411712.33333333333341397.0Region8-Cys3 region
TgeneLTBP1chr11:65307956chr2:33518226ENST0000039000314301507_1721712.33333333333341397.0RegionC-terminal domain
TgeneLTBP1chr11:65307956chr2:33518226ENST0000040452514301344_1411658.33333333333341343.0Region8-Cys3 region
TgeneLTBP1chr11:65307956chr2:33518226ENST0000040452514301507_1721658.33333333333341343.0RegionC-terminal domain
TgeneLTBP1chr11:65307956chr2:33518226ENST0000040481618341344_14111037.33333333333331722.0Region8-Cys3 region
TgeneLTBP1chr11:65307956chr2:33518226ENST0000040481618341507_17211037.33333333333331722.0RegionC-terminal domain
TgeneLTBP1chr11:65307956chr2:33518226ENST0000040792514301344_1411711.33333333333341396.0Region8-Cys3 region
TgeneLTBP1chr11:65307956chr2:33518226ENST0000040792514301507_1721711.33333333333341396.0RegionC-terminal domain

- Not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneLTBP3chr11:65307956chr2:33518226ENST00000301873-22281036_10761035.33333333333331304.0DomainEGF-like 11%3B calcium-binding
HgeneLTBP3chr11:65307956chr2:33518226ENST00000301873-22281082_11221035.33333333333331304.0DomainEGF-like 12%3B calcium-binding
HgeneLTBP3chr11:65307956chr2:33518226ENST00000301873-22281136_11861035.33333333333331304.0DomainTB 4
HgeneLTBP3chr11:65307956chr2:33518226ENST00000301873-22281254_12981035.33333333333331304.0DomainEGF-like 13%3B calcium-binding
HgeneLTBP3chr11:65307956chr2:33518226ENST00000322147-22271036_10761035.33333333333331257.0DomainEGF-like 11%3B calcium-binding
HgeneLTBP3chr11:65307956chr2:33518226ENST00000322147-22271082_11221035.33333333333331257.0DomainEGF-like 12%3B calcium-binding
HgeneLTBP3chr11:65307956chr2:33518226ENST00000322147-22271136_11861035.33333333333331257.0DomainTB 4
HgeneLTBP3chr11:65307956chr2:33518226ENST00000322147-22271254_12981035.33333333333331257.0DomainEGF-like 13%3B calcium-binding
TgeneLTBP1chr11:65307956chr2:33518226ENST000003544761834100_1301038.33333333333331723.0Compositional biasNote=Pro-rich
TgeneLTBP1chr11:65307956chr2:33518226ENST000003900031430100_130712.33333333333341397.0Compositional biasNote=Pro-rich
TgeneLTBP1chr11:65307956chr2:33518226ENST000004045251430100_130658.33333333333341343.0Compositional biasNote=Pro-rich
TgeneLTBP1chr11:65307956chr2:33518226ENST000004048161834100_1301037.33333333333331722.0Compositional biasNote=Pro-rich
TgeneLTBP1chr11:65307956chr2:33518226ENST000004079251430100_130711.33333333333341396.0Compositional biasNote=Pro-rich
TgeneLTBP1chr11:65307956chr2:33518226ENST000003544761834187_2191038.33333333333331723.0DomainEGF-like 1
TgeneLTBP1chr11:65307956chr2:33518226ENST000003544761834399_4311038.33333333333331723.0DomainEGF-like 2
TgeneLTBP1chr11:65307956chr2:33518226ENST000003544761834557_6091038.33333333333331723.0DomainTB 1
TgeneLTBP1chr11:65307956chr2:33518226ENST000003544761834626_6631038.33333333333331723.0DomainEGF-like 3%3B calcium-binding
TgeneLTBP1chr11:65307956chr2:33518226ENST000003544761834677_7291038.33333333333331723.0DomainTB 2
TgeneLTBP1chr11:65307956chr2:33518226ENST000003544761834873_9101038.33333333333331723.0DomainEGF-like 4%3B calcium-binding
TgeneLTBP1chr11:65307956chr2:33518226ENST000003544761834915_9561038.33333333333331723.0DomainEGF-like 5%3B calcium-binding
TgeneLTBP1chr11:65307956chr2:33518226ENST000003544761834957_9971038.33333333333331723.0DomainEGF-like 6%3B calcium-binding
TgeneLTBP1chr11:65307956chr2:33518226ENST000003544761834998_10371038.33333333333331723.0DomainEGF-like 7%3B calcium-binding
TgeneLTBP1chr11:65307956chr2:33518226ENST000003900031430187_219712.33333333333341397.0DomainEGF-like 1
TgeneLTBP1chr11:65307956chr2:33518226ENST000003900031430399_431712.33333333333341397.0DomainEGF-like 2
TgeneLTBP1chr11:65307956chr2:33518226ENST000003900031430557_609712.33333333333341397.0DomainTB 1
TgeneLTBP1chr11:65307956chr2:33518226ENST000003900031430626_663712.33333333333341397.0DomainEGF-like 3%3B calcium-binding
TgeneLTBP1chr11:65307956chr2:33518226ENST000003900031430677_729712.33333333333341397.0DomainTB 2
TgeneLTBP1chr11:65307956chr2:33518226ENST000004045251430187_219658.33333333333341343.0DomainEGF-like 1
TgeneLTBP1chr11:65307956chr2:33518226ENST000004045251430399_431658.33333333333341343.0DomainEGF-like 2
TgeneLTBP1chr11:65307956chr2:33518226ENST000004045251430557_609658.33333333333341343.0DomainTB 1
TgeneLTBP1chr11:65307956chr2:33518226ENST000004045251430626_663658.33333333333341343.0DomainEGF-like 3%3B calcium-binding
TgeneLTBP1chr11:65307956chr2:33518226ENST000004048161834187_2191037.33333333333331722.0DomainEGF-like 1
TgeneLTBP1chr11:65307956chr2:33518226ENST000004048161834399_4311037.33333333333331722.0DomainEGF-like 2
TgeneLTBP1chr11:65307956chr2:33518226ENST000004048161834557_6091037.33333333333331722.0DomainTB 1
TgeneLTBP1chr11:65307956chr2:33518226ENST000004048161834626_6631037.33333333333331722.0DomainEGF-like 3%3B calcium-binding
TgeneLTBP1chr11:65307956chr2:33518226ENST000004048161834677_7291037.33333333333331722.0DomainTB 2
TgeneLTBP1chr11:65307956chr2:33518226ENST000004048161834873_9101037.33333333333331722.0DomainEGF-like 4%3B calcium-binding
TgeneLTBP1chr11:65307956chr2:33518226ENST000004048161834915_9561037.33333333333331722.0DomainEGF-like 5%3B calcium-binding
TgeneLTBP1chr11:65307956chr2:33518226ENST000004048161834957_9971037.33333333333331722.0DomainEGF-like 6%3B calcium-binding
TgeneLTBP1chr11:65307956chr2:33518226ENST000004048161834998_10371037.33333333333331722.0DomainEGF-like 7%3B calcium-binding
TgeneLTBP1chr11:65307956chr2:33518226ENST000004079251430187_219711.33333333333341396.0DomainEGF-like 1
TgeneLTBP1chr11:65307956chr2:33518226ENST000004079251430399_431711.33333333333341396.0DomainEGF-like 2
TgeneLTBP1chr11:65307956chr2:33518226ENST000004079251430557_609711.33333333333341396.0DomainTB 1
TgeneLTBP1chr11:65307956chr2:33518226ENST000004079251430626_663711.33333333333341396.0DomainEGF-like 3%3B calcium-binding
TgeneLTBP1chr11:65307956chr2:33518226ENST000004079251430677_729711.33333333333341396.0DomainTB 2


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Fusion Protein Structures

check button PDB and CIF files of the predicted fusion proteins
* Here we show the 3D structure of the fusion proteins using Mol*. AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Model confidence is shown from the pLDDT values per residue. pLDDT corresponds to the model’s prediction of its score on the local Distance Difference Test. It is a measure of local accuracy (from AlphfaFold website). To color code individual residues, we transformed individual PDB files into CIF format.
Fusion protein PDB link (fusion AA seq ID in FusionPDB)HgeneHchrHbpHstrandTgeneTchrTbpTstrandAA seqLen(AA seq)


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pLDDT score distribution

check button pLDDT score distribution of the predicted wild-type structures of two partner proteins from AlphaFold2
* AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100.
LTBP3_pLDDT.png
all structure
all structure
LTBP1_pLDDT.png
all structure
all structure

check button pLDDT score distribution of the predicted fusion protein structures from AlphaFold2
* AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100.


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Ramachandran Plot of Fusion Protein Structure


check button Ramachandran plot of the torsional angles - phi (φ)and psi (ψ) - of the residues (amino acids) contained in this fusion protein peptide.
Fusion AA seq ID in FusionPDB and their Ramachandran plots

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Fusion Protein-Protein Interaction


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type from validated records (BIOGRID-3.4.160)
GenePPI interactors


check button Protein-protein interactors based on sequence similarity (STRING)
GeneSTRING network
LTBP3
LTBP1


check button - Retained interactions in fusion protein (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost interactions due to fusion (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs to LTBP3-LTBP1


check button Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDrugSourcePMID

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Related Diseases to LTBP3-LTBP1


check button Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDiseaseSourcePMID

check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource