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Center for Computational Systems Medicine level2
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Fusion Gene Summary

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Fusion Gene Sample Information

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Fusion ORF Analysis

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Fusion Amino Acid Sequences

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Fusion Protein Functional Features

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Fusion Protein Structure

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pLDDT scores

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Ramachandran Plot of Fusion Protein Structure

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Fusion Protein-Protein Interaction

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Related drugs with this fusion protein

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Related disease with this fusion protein

Fusion Protein:MAGED2-TRO

Fusion Protein Summary

check button Fusion gene summary
Fusion partner gene informationFusion gene name: MAGED2-TRO
FusionPDB ID: 50770
FusionGDB2.0 ID: 50770
HgeneTgene
Gene symbol

MAGED2

TRO

Gene ID

10916

7216

Gene nameMAGE family member D2trophinin
Synonyms11B6|BARTS5|BCG-1|BCG1|HCA10|MAGE-D2MAGE-d3|MAGED3
Cytomap

Xp11.21

Xp11.21

Type of geneprotein-codingprotein-coding
Descriptionmelanoma-associated antigen D2MAGE-D2 antigenbreast cancer-associated gene 1 proteinhepatocellular carcinoma-associated protein JCL-1melanoma antigen family D, 2melanoma antigen family D2trophininMAGE superfamily proteinMAGE-D3 antigenmagphininmelanoma antigen, family D, 3
Modification date2020031320200320
UniProtAcc

Q9UNF1

TNNT1

Ensembl transtripts involved in fusion geneENST idsENST00000218439, ENST00000347546, 
ENST00000375053, ENST00000375058, 
ENST00000375060, ENST00000375062, 
ENST00000375068, ENST00000396224, 
ENST00000497484, 		ENST00000375041, 
ENST00000420798, ENST00000484031, 
ENST00000173898, ENST00000319167, 
ENST00000375022, ENST00000399736, 
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)* DoF score13 X 9 X 4=4684 X 4 X 2=32
# samples 134
** MAII scorelog2(13/468*10)=-1.84799690655495
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(4/32*10)=0.321928094887362
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context (manual curation of fusion genes in FusionPDB)

PubMed: MAGED2 [Title/Abstract] AND TRO [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)TRO(54953058)-MAGED2(54839921), # samples:50
MAGED2(54839457)-TRO(54953016), # samples:4
Anticipated loss of major functional domain due to fusion event.TRO-MAGED2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
TRO-MAGED2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
MAGED2-TRO seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
MAGED2-TRO seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
MAGED2-TRO seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
MAGED2-TRO seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across MAGED2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across TRO (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure


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Fusion Gene Sample Information

check buttonFusion gene information from FusionGDB2.0.
check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-A7-A13F-01AMAGED2chrX

54839457

+TROchrX

54953016

+
ChimerDB4BRCATCGA-E2-A1BC-01AMAGED2chrX

54839457

+TROchrX

54953016

+
ChimerDB4BRCATCGA-EW-A2FW-01AMAGED2chrX

54839457

+TROchrX

54953016

+
ChimerDB4KIRCTCGA-B0-5710-01AMAGED2chrX

54839457

+TROchrX

54953016

+


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Fusion ORF Analysis


check buttonFusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000375068MAGED2chrX54839457+ENST00000319167TROchrX54953016+195513982331861542
ENST00000375068MAGED2chrX54839457+ENST00000173898TROchrX54953016+4276139823340361267
ENST00000375068MAGED2chrX54839457+ENST00000399736TROchrX54953016+195513982331861542
ENST00000375068MAGED2chrX54839457+ENST00000375022TROchrX54953016+195513982331861542
ENST00000375053MAGED2chrX54839457+ENST00000319167TROchrX54953016+18161259941722542
ENST00000375053MAGED2chrX54839457+ENST00000173898TROchrX54953016+413712599438971267
ENST00000375053MAGED2chrX54839457+ENST00000399736TROchrX54953016+18161259941722542
ENST00000375053MAGED2chrX54839457+ENST00000375022TROchrX54953016+18161259941722542
ENST00000347546MAGED2chrX54839457+ENST00000319167TROchrX54953016+17531196851659524
ENST00000347546MAGED2chrX54839457+ENST00000173898TROchrX54953016+407411968538341249
ENST00000347546MAGED2chrX54839457+ENST00000399736TROchrX54953016+17531196851659524
ENST00000347546MAGED2chrX54839457+ENST00000375022TROchrX54953016+17531196851659524
ENST00000375062MAGED2chrX54839457+ENST00000319167TROchrX54953016+1536979691442457
ENST00000375062MAGED2chrX54839457+ENST00000173898TROchrX54953016+38579796936171182
ENST00000375062MAGED2chrX54839457+ENST00000399736TROchrX54953016+1536979691442457
ENST00000375062MAGED2chrX54839457+ENST00000375022TROchrX54953016+1536979691442457
ENST00000218439MAGED2chrX54839457+ENST00000319167TROchrX54953016+18211264991727542
ENST00000218439MAGED2chrX54839457+ENST00000173898TROchrX54953016+414212649939021267
ENST00000218439MAGED2chrX54839457+ENST00000399736TROchrX54953016+18211264991727542
ENST00000218439MAGED2chrX54839457+ENST00000375022TROchrX54953016+18211264991727542
ENST00000375058MAGED2chrX54839457+ENST00000319167TROchrX54953016+18141257921720542
ENST00000375058MAGED2chrX54839457+ENST00000173898TROchrX54953016+413512579238951267
ENST00000375058MAGED2chrX54839457+ENST00000399736TROchrX54953016+18141257921720542
ENST00000375058MAGED2chrX54839457+ENST00000375022TROchrX54953016+18141257921720542
ENST00000375060MAGED2chrX54839457+ENST00000319167TROchrX54953016+15591002921465457
ENST00000375060MAGED2chrX54839457+ENST00000173898TROchrX54953016+388010029236401182
ENST00000375060MAGED2chrX54839457+ENST00000399736TROchrX54953016+15591002921465457
ENST00000375060MAGED2chrX54839457+ENST00000375022TROchrX54953016+15591002921465457
ENST00000396224MAGED2chrX54839457+ENST00000319167TROchrX54953016+191513581931821542
ENST00000396224MAGED2chrX54839457+ENST00000173898TROchrX54953016+4236135819339961267
ENST00000396224MAGED2chrX54839457+ENST00000399736TROchrX54953016+191513581931821542
ENST00000396224MAGED2chrX54839457+ENST00000375022TROchrX54953016+191513581931821542

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000375068ENST00000319167MAGED2chrX54839457+TROchrX54953016+0.0182833470.9817167
ENST00000375068ENST00000173898MAGED2chrX54839457+TROchrX54953016+0.0077362590.9922638
ENST00000375068ENST00000399736MAGED2chrX54839457+TROchrX54953016+0.0182833470.9817167
ENST00000375068ENST00000375022MAGED2chrX54839457+TROchrX54953016+0.0182833470.9817167
ENST00000375053ENST00000319167MAGED2chrX54839457+TROchrX54953016+0.0181648170.9818351
ENST00000375053ENST00000173898MAGED2chrX54839457+TROchrX54953016+0.0067201430.9932799
ENST00000375053ENST00000399736MAGED2chrX54839457+TROchrX54953016+0.0181648170.9818351
ENST00000375053ENST00000375022MAGED2chrX54839457+TROchrX54953016+0.0181648170.9818351
ENST00000347546ENST00000319167MAGED2chrX54839457+TROchrX54953016+0.0145760580.985424
ENST00000347546ENST00000173898MAGED2chrX54839457+TROchrX54953016+0.0071847140.99281526
ENST00000347546ENST00000399736MAGED2chrX54839457+TROchrX54953016+0.0145760580.985424
ENST00000347546ENST00000375022MAGED2chrX54839457+TROchrX54953016+0.0145760580.985424
ENST00000375062ENST00000319167MAGED2chrX54839457+TROchrX54953016+0.010039840.9899602
ENST00000375062ENST00000173898MAGED2chrX54839457+TROchrX54953016+0.0065142880.99348575
ENST00000375062ENST00000399736MAGED2chrX54839457+TROchrX54953016+0.010039840.9899602
ENST00000375062ENST00000375022MAGED2chrX54839457+TROchrX54953016+0.010039840.9899602
ENST00000218439ENST00000319167MAGED2chrX54839457+TROchrX54953016+0.0161809570.98381907
ENST00000218439ENST00000173898MAGED2chrX54839457+TROchrX54953016+0.0064153030.9935847
ENST00000218439ENST00000399736MAGED2chrX54839457+TROchrX54953016+0.0161809570.98381907
ENST00000218439ENST00000375022MAGED2chrX54839457+TROchrX54953016+0.0161809570.98381907
ENST00000375058ENST00000319167MAGED2chrX54839457+TROchrX54953016+0.0161532740.9838468
ENST00000375058ENST00000173898MAGED2chrX54839457+TROchrX54953016+0.0063340970.9936659
ENST00000375058ENST00000399736MAGED2chrX54839457+TROchrX54953016+0.0161532740.9838468
ENST00000375058ENST00000375022MAGED2chrX54839457+TROchrX54953016+0.0161532740.9838468
ENST00000375060ENST00000319167MAGED2chrX54839457+TROchrX54953016+0.0087494780.9912505
ENST00000375060ENST00000173898MAGED2chrX54839457+TROchrX54953016+0.0062104610.9937895
ENST00000375060ENST00000399736MAGED2chrX54839457+TROchrX54953016+0.0087494780.9912505
ENST00000375060ENST00000375022MAGED2chrX54839457+TROchrX54953016+0.0087494780.9912505
ENST00000396224ENST00000319167MAGED2chrX54839457+TROchrX54953016+0.0156161520.9843838
ENST00000396224ENST00000173898MAGED2chrX54839457+TROchrX54953016+0.006721060.9932789
ENST00000396224ENST00000399736MAGED2chrX54839457+TROchrX54953016+0.0156161520.9843838
ENST00000396224ENST00000375022MAGED2chrX54839457+TROchrX54953016+0.0156161520.9843838

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Fusion Amino Acid Sequences


check button For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

>50770_50770_1_MAGED2-TRO_MAGED2_chrX_54839457_ENST00000218439_TRO_chrX_54953016_ENST00000173898_length(amino acids)=1267AA_BP=331
MSDTSESGAGLTRFQAEASEKDSSSMMQTLLTVTQNVEVPETPKASKALEVSEDVKVSKASGVSKATEVSKTPEAREAPATQASSTTQLT
DTQVLAAENKSLAADTKKQNADPQAVTMPATETKKVSHVADTKVNTKAQETEAAPSQAPADEPEPESAAAQSQENQDTRPKVKAKKARKV
KHLDGEEDGSSDQSQASGTTGGRRVSKALMASMARRASRGPIAFWARRASRTRLAAWARRALLSLRSPKARRGKARRRAAKLQSSQEPEA
PPPRDVALLQGRANDLVKYLLAKDQTKIPIKRSDMLKDIIKEYTDVYPEIIERAGYSLEKVFGIQLKEIDKNDHLYILLSTLEPTDAGIL
GTTKDSPKLGLLMVLLSIIFMNGNRSSEAVIWEVLRKLGLRPGVRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRPPEYEFFWGLRSYHE
TSKMKVLKFACRVQKKDPKDWAVQYREAVEMEVQAAAVAVAEAEARAEARAQMGIGEEAVAGPWNWDDMDIDCLTREELGDDAQAWSRFS
FEIEARAQENADASTNVNFSRGASTRAGFSDGASISFNGAPSSSGGFSGGPGITFGVAPSTSASFSNTASISFGGTLSTSSSFSSAASIS
FGCAHSTSTSFSSEASISFGGMPCTSASFSGGVSSSFSGPLSTSATFSGGASSGFGGTLSTTAGFSGVLSTSTSFGSAPTTSTVFSSALS
TSTGFGGILSTSVCFGGSPSSSGSFGGTLSTSICFGGSPCTSTGFGGTLSTSVSFGGSSSTSANFGGTLSTSICFDGSPSTGAGFGGALN
TSASFGSVLNTSTGFGGAMSTSADFGGTLSTSVCFGGSPGTSVSFGSALNTNAGYGGAVSTNTDFGGTLSTSVCFGGSPSTSAGFGGALN
TNASFGCAVSTSASFSGAVSTSACFSGAPITNPGFGGAFSTSAGFGGALSTAADFGGTPSNSIGFGAAPSTSVSFGGAHGTSLCFGGAPS
TSLCFGSASNTNLCFGGPPSTSACFSGATSPSFCDGPSTSTGFSFGNGLSTNAGFGGGLNTSAGFGGGLGTSAGFSGGLSTSSGFDGGLG
TSAGFGGGPGTSTGFGGGLGTSAGFSGGLGTSAGFGGGLVTSDGFGGGLGTNASFGSTLGTSAGFSGGLSTSDGFGSRPNASFDRGLSTI
IGFGSGSNTSTGFTGEPSTSTGFSSGPSSIVGFSGGPSTGVGFCSGPSTSGFSGGPSTGAGFGGGPNTGAGFGGGPSTSAGFGSGAASLG

--------------------------------------------------------------

>50770_50770_2_MAGED2-TRO_MAGED2_chrX_54839457_ENST00000218439_TRO_chrX_54953016_ENST00000319167_length(amino acids)=542AA_BP=271
MSDTSESGAGLTRFQAEASEKDSSSMMQTLLTVTQNVEVPETPKASKALEVSEDVKVSKASGVSKATEVSKTPEAREAPATQASSTTQLT
DTQVLAAENKSLAADTKKQNADPQAVTMPATETKKVSHVADTKVNTKAQETEAAPSQAPADEPEPESAAAQSQENQDTRPKVKAKKARKV
KHLDGEEDGSSDQSQASGTTGGRRVSKALMASMARRASRGPIAFWARRASRTRLAAWARRALLSLRSPKARRGKARRRAAKLQSSQEPEA
PPPRDVALLQGRANDLVKYLLAKDQTKIPIKRSDMLKDIIKEYTDVYPEIIERAGYSLEKVFGIQLKEIDKNDHLYILLSTLEPTDAGIL
GTTKDSPKLGLLMVLLSIIFMNGNRSSEAVIWEVLRKLGLRPGVRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRPPEYEFFWGLRSYHE
TSKMKVLKFACRVQKKDPKDWAVQYREAVEMEVQAAAVAVAEAEARAEIYSPCLQIPLINCSSPSHGAKVHPWNLCPHSSQGSYGQSAEG

--------------------------------------------------------------

>50770_50770_3_MAGED2-TRO_MAGED2_chrX_54839457_ENST00000218439_TRO_chrX_54953016_ENST00000375022_length(amino acids)=542AA_BP=271
MSDTSESGAGLTRFQAEASEKDSSSMMQTLLTVTQNVEVPETPKASKALEVSEDVKVSKASGVSKATEVSKTPEAREAPATQASSTTQLT
DTQVLAAENKSLAADTKKQNADPQAVTMPATETKKVSHVADTKVNTKAQETEAAPSQAPADEPEPESAAAQSQENQDTRPKVKAKKARKV
KHLDGEEDGSSDQSQASGTTGGRRVSKALMASMARRASRGPIAFWARRASRTRLAAWARRALLSLRSPKARRGKARRRAAKLQSSQEPEA
PPPRDVALLQGRANDLVKYLLAKDQTKIPIKRSDMLKDIIKEYTDVYPEIIERAGYSLEKVFGIQLKEIDKNDHLYILLSTLEPTDAGIL
GTTKDSPKLGLLMVLLSIIFMNGNRSSEAVIWEVLRKLGLRPGVRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRPPEYEFFWGLRSYHE
TSKMKVLKFACRVQKKDPKDWAVQYREAVEMEVQAAAVAVAEAEARAEIYSPCLQIPLINCSSPSHGAKVHPWNLCPHSSQGSYGQSAEG

--------------------------------------------------------------

>50770_50770_4_MAGED2-TRO_MAGED2_chrX_54839457_ENST00000218439_TRO_chrX_54953016_ENST00000399736_length(amino acids)=542AA_BP=271
MSDTSESGAGLTRFQAEASEKDSSSMMQTLLTVTQNVEVPETPKASKALEVSEDVKVSKASGVSKATEVSKTPEAREAPATQASSTTQLT
DTQVLAAENKSLAADTKKQNADPQAVTMPATETKKVSHVADTKVNTKAQETEAAPSQAPADEPEPESAAAQSQENQDTRPKVKAKKARKV
KHLDGEEDGSSDQSQASGTTGGRRVSKALMASMARRASRGPIAFWARRASRTRLAAWARRALLSLRSPKARRGKARRRAAKLQSSQEPEA
PPPRDVALLQGRANDLVKYLLAKDQTKIPIKRSDMLKDIIKEYTDVYPEIIERAGYSLEKVFGIQLKEIDKNDHLYILLSTLEPTDAGIL
GTTKDSPKLGLLMVLLSIIFMNGNRSSEAVIWEVLRKLGLRPGVRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRPPEYEFFWGLRSYHE
TSKMKVLKFACRVQKKDPKDWAVQYREAVEMEVQAAAVAVAEAEARAEIYSPCLQIPLINCSSPSHGAKVHPWNLCPHSSQGSYGQSAEG

--------------------------------------------------------------

>50770_50770_5_MAGED2-TRO_MAGED2_chrX_54839457_ENST00000347546_TRO_chrX_54953016_ENST00000173898_length(amino acids)=1249AA_BP=313
MSDTSESGAGLTRFQAEASEKDSSSMMQTLLTVTQNVEVPETPKASKATEVSKTPEAREAPATQASSTTQLTDTQVLAAENKSLAADTKK
QNADPQAVTMPATETKKVSHVADTKVNTKAQETEAAPSQAPADEPEPESAAAQSQENQDTRPKVKAKKARKVKHLDGEEDGSSDQSQASG
TTGGRRVSKALMASMARRASRGPIAFWARRASRTRLAAWARRALLSLRSPKARRGKARRRAAKLQSSQEPEAPPPRDVALLQGRANDLVK
YLLAKDQTKIPIKRSDMLKDIIKEYTDVYPEIIERAGYSLEKVFGIQLKEIDKNDHLYILLSTLEPTDAGILGTTKDSPKLGLLMVLLSI
IFMNGNRSSEAVIWEVLRKLGLRPGVRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRPPEYEFFWGLRSYHETSKMKVLKFACRVQKKDP
KDWAVQYREAVEMEVQAAAVAVAEAEARAEARAQMGIGEEAVAGPWNWDDMDIDCLTREELGDDAQAWSRFSFEIEARAQENADASTNVN
FSRGASTRAGFSDGASISFNGAPSSSGGFSGGPGITFGVAPSTSASFSNTASISFGGTLSTSSSFSSAASISFGCAHSTSTSFSSEASIS
FGGMPCTSASFSGGVSSSFSGPLSTSATFSGGASSGFGGTLSTTAGFSGVLSTSTSFGSAPTTSTVFSSALSTSTGFGGILSTSVCFGGS
PSSSGSFGGTLSTSICFGGSPCTSTGFGGTLSTSVSFGGSSSTSANFGGTLSTSICFDGSPSTGAGFGGALNTSASFGSVLNTSTGFGGA
MSTSADFGGTLSTSVCFGGSPGTSVSFGSALNTNAGYGGAVSTNTDFGGTLSTSVCFGGSPSTSAGFGGALNTNASFGCAVSTSASFSGA
VSTSACFSGAPITNPGFGGAFSTSAGFGGALSTAADFGGTPSNSIGFGAAPSTSVSFGGAHGTSLCFGGAPSTSLCFGSASNTNLCFGGP
PSTSACFSGATSPSFCDGPSTSTGFSFGNGLSTNAGFGGGLNTSAGFGGGLGTSAGFSGGLSTSSGFDGGLGTSAGFGGGPGTSTGFGGG
LGTSAGFSGGLGTSAGFGGGLVTSDGFGGGLGTNASFGSTLGTSAGFSGGLSTSDGFGSRPNASFDRGLSTIIGFGSGSNTSTGFTGEPS

--------------------------------------------------------------

>50770_50770_6_MAGED2-TRO_MAGED2_chrX_54839457_ENST00000347546_TRO_chrX_54953016_ENST00000319167_length(amino acids)=524AA_BP=253
MSDTSESGAGLTRFQAEASEKDSSSMMQTLLTVTQNVEVPETPKASKATEVSKTPEAREAPATQASSTTQLTDTQVLAAENKSLAADTKK
QNADPQAVTMPATETKKVSHVADTKVNTKAQETEAAPSQAPADEPEPESAAAQSQENQDTRPKVKAKKARKVKHLDGEEDGSSDQSQASG
TTGGRRVSKALMASMARRASRGPIAFWARRASRTRLAAWARRALLSLRSPKARRGKARRRAAKLQSSQEPEAPPPRDVALLQGRANDLVK
YLLAKDQTKIPIKRSDMLKDIIKEYTDVYPEIIERAGYSLEKVFGIQLKEIDKNDHLYILLSTLEPTDAGILGTTKDSPKLGLLMVLLSI
IFMNGNRSSEAVIWEVLRKLGLRPGVRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRPPEYEFFWGLRSYHETSKMKVLKFACRVQKKDP

--------------------------------------------------------------

>50770_50770_7_MAGED2-TRO_MAGED2_chrX_54839457_ENST00000347546_TRO_chrX_54953016_ENST00000375022_length(amino acids)=524AA_BP=253
MSDTSESGAGLTRFQAEASEKDSSSMMQTLLTVTQNVEVPETPKASKATEVSKTPEAREAPATQASSTTQLTDTQVLAAENKSLAADTKK
QNADPQAVTMPATETKKVSHVADTKVNTKAQETEAAPSQAPADEPEPESAAAQSQENQDTRPKVKAKKARKVKHLDGEEDGSSDQSQASG
TTGGRRVSKALMASMARRASRGPIAFWARRASRTRLAAWARRALLSLRSPKARRGKARRRAAKLQSSQEPEAPPPRDVALLQGRANDLVK
YLLAKDQTKIPIKRSDMLKDIIKEYTDVYPEIIERAGYSLEKVFGIQLKEIDKNDHLYILLSTLEPTDAGILGTTKDSPKLGLLMVLLSI
IFMNGNRSSEAVIWEVLRKLGLRPGVRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRPPEYEFFWGLRSYHETSKMKVLKFACRVQKKDP

--------------------------------------------------------------

>50770_50770_8_MAGED2-TRO_MAGED2_chrX_54839457_ENST00000347546_TRO_chrX_54953016_ENST00000399736_length(amino acids)=524AA_BP=253
MSDTSESGAGLTRFQAEASEKDSSSMMQTLLTVTQNVEVPETPKASKATEVSKTPEAREAPATQASSTTQLTDTQVLAAENKSLAADTKK
QNADPQAVTMPATETKKVSHVADTKVNTKAQETEAAPSQAPADEPEPESAAAQSQENQDTRPKVKAKKARKVKHLDGEEDGSSDQSQASG
TTGGRRVSKALMASMARRASRGPIAFWARRASRTRLAAWARRALLSLRSPKARRGKARRRAAKLQSSQEPEAPPPRDVALLQGRANDLVK
YLLAKDQTKIPIKRSDMLKDIIKEYTDVYPEIIERAGYSLEKVFGIQLKEIDKNDHLYILLSTLEPTDAGILGTTKDSPKLGLLMVLLSI
IFMNGNRSSEAVIWEVLRKLGLRPGVRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRPPEYEFFWGLRSYHETSKMKVLKFACRVQKKDP

--------------------------------------------------------------

>50770_50770_9_MAGED2-TRO_MAGED2_chrX_54839457_ENST00000375053_TRO_chrX_54953016_ENST00000173898_length(amino acids)=1267AA_BP=331
MSDTSESGAGLTRFQAEASEKDSSSMMQTLLTVTQNVEVPETPKASKALEVSEDVKVSKASGVSKATEVSKTPEAREAPATQASSTTQLT
DTQVLAAENKSLAADTKKQNADPQAVTMPATETKKVSHVADTKVNTKAQETEAAPSQAPADEPEPESAAAQSQENQDTRPKVKAKKARKV
KHLDGEEDGSSDQSQASGTTGGRRVSKALMASMARRASRGPIAFWARRASRTRLAAWARRALLSLRSPKARRGKARRRAAKLQSSQEPEA
PPPRDVALLQGRANDLVKYLLAKDQTKIPIKRSDMLKDIIKEYTDVYPEIIERAGYSLEKVFGIQLKEIDKNDHLYILLSTLEPTDAGIL
GTTKDSPKLGLLMVLLSIIFMNGNRSSEAVIWEVLRKLGLRPGVRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRPPEYEFFWGLRSYHE
TSKMKVLKFACRVQKKDPKDWAVQYREAVEMEVQAAAVAVAEAEARAEARAQMGIGEEAVAGPWNWDDMDIDCLTREELGDDAQAWSRFS
FEIEARAQENADASTNVNFSRGASTRAGFSDGASISFNGAPSSSGGFSGGPGITFGVAPSTSASFSNTASISFGGTLSTSSSFSSAASIS
FGCAHSTSTSFSSEASISFGGMPCTSASFSGGVSSSFSGPLSTSATFSGGASSGFGGTLSTTAGFSGVLSTSTSFGSAPTTSTVFSSALS
TSTGFGGILSTSVCFGGSPSSSGSFGGTLSTSICFGGSPCTSTGFGGTLSTSVSFGGSSSTSANFGGTLSTSICFDGSPSTGAGFGGALN
TSASFGSVLNTSTGFGGAMSTSADFGGTLSTSVCFGGSPGTSVSFGSALNTNAGYGGAVSTNTDFGGTLSTSVCFGGSPSTSAGFGGALN
TNASFGCAVSTSASFSGAVSTSACFSGAPITNPGFGGAFSTSAGFGGALSTAADFGGTPSNSIGFGAAPSTSVSFGGAHGTSLCFGGAPS
TSLCFGSASNTNLCFGGPPSTSACFSGATSPSFCDGPSTSTGFSFGNGLSTNAGFGGGLNTSAGFGGGLGTSAGFSGGLSTSSGFDGGLG
TSAGFGGGPGTSTGFGGGLGTSAGFSGGLGTSAGFGGGLVTSDGFGGGLGTNASFGSTLGTSAGFSGGLSTSDGFGSRPNASFDRGLSTI
IGFGSGSNTSTGFTGEPSTSTGFSSGPSSIVGFSGGPSTGVGFCSGPSTSGFSGGPSTGAGFGGGPNTGAGFGGGPSTSAGFGSGAASLG

--------------------------------------------------------------

>50770_50770_10_MAGED2-TRO_MAGED2_chrX_54839457_ENST00000375053_TRO_chrX_54953016_ENST00000319167_length(amino acids)=542AA_BP=271
MSDTSESGAGLTRFQAEASEKDSSSMMQTLLTVTQNVEVPETPKASKALEVSEDVKVSKASGVSKATEVSKTPEAREAPATQASSTTQLT
DTQVLAAENKSLAADTKKQNADPQAVTMPATETKKVSHVADTKVNTKAQETEAAPSQAPADEPEPESAAAQSQENQDTRPKVKAKKARKV
KHLDGEEDGSSDQSQASGTTGGRRVSKALMASMARRASRGPIAFWARRASRTRLAAWARRALLSLRSPKARRGKARRRAAKLQSSQEPEA
PPPRDVALLQGRANDLVKYLLAKDQTKIPIKRSDMLKDIIKEYTDVYPEIIERAGYSLEKVFGIQLKEIDKNDHLYILLSTLEPTDAGIL
GTTKDSPKLGLLMVLLSIIFMNGNRSSEAVIWEVLRKLGLRPGVRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRPPEYEFFWGLRSYHE
TSKMKVLKFACRVQKKDPKDWAVQYREAVEMEVQAAAVAVAEAEARAEIYSPCLQIPLINCSSPSHGAKVHPWNLCPHSSQGSYGQSAEG

--------------------------------------------------------------

>50770_50770_11_MAGED2-TRO_MAGED2_chrX_54839457_ENST00000375053_TRO_chrX_54953016_ENST00000375022_length(amino acids)=542AA_BP=271
MSDTSESGAGLTRFQAEASEKDSSSMMQTLLTVTQNVEVPETPKASKALEVSEDVKVSKASGVSKATEVSKTPEAREAPATQASSTTQLT
DTQVLAAENKSLAADTKKQNADPQAVTMPATETKKVSHVADTKVNTKAQETEAAPSQAPADEPEPESAAAQSQENQDTRPKVKAKKARKV
KHLDGEEDGSSDQSQASGTTGGRRVSKALMASMARRASRGPIAFWARRASRTRLAAWARRALLSLRSPKARRGKARRRAAKLQSSQEPEA
PPPRDVALLQGRANDLVKYLLAKDQTKIPIKRSDMLKDIIKEYTDVYPEIIERAGYSLEKVFGIQLKEIDKNDHLYILLSTLEPTDAGIL
GTTKDSPKLGLLMVLLSIIFMNGNRSSEAVIWEVLRKLGLRPGVRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRPPEYEFFWGLRSYHE
TSKMKVLKFACRVQKKDPKDWAVQYREAVEMEVQAAAVAVAEAEARAEIYSPCLQIPLINCSSPSHGAKVHPWNLCPHSSQGSYGQSAEG

--------------------------------------------------------------

>50770_50770_12_MAGED2-TRO_MAGED2_chrX_54839457_ENST00000375053_TRO_chrX_54953016_ENST00000399736_length(amino acids)=542AA_BP=271
MSDTSESGAGLTRFQAEASEKDSSSMMQTLLTVTQNVEVPETPKASKALEVSEDVKVSKASGVSKATEVSKTPEAREAPATQASSTTQLT
DTQVLAAENKSLAADTKKQNADPQAVTMPATETKKVSHVADTKVNTKAQETEAAPSQAPADEPEPESAAAQSQENQDTRPKVKAKKARKV
KHLDGEEDGSSDQSQASGTTGGRRVSKALMASMARRASRGPIAFWARRASRTRLAAWARRALLSLRSPKARRGKARRRAAKLQSSQEPEA
PPPRDVALLQGRANDLVKYLLAKDQTKIPIKRSDMLKDIIKEYTDVYPEIIERAGYSLEKVFGIQLKEIDKNDHLYILLSTLEPTDAGIL
GTTKDSPKLGLLMVLLSIIFMNGNRSSEAVIWEVLRKLGLRPGVRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRPPEYEFFWGLRSYHE
TSKMKVLKFACRVQKKDPKDWAVQYREAVEMEVQAAAVAVAEAEARAEIYSPCLQIPLINCSSPSHGAKVHPWNLCPHSSQGSYGQSAEG

--------------------------------------------------------------

>50770_50770_13_MAGED2-TRO_MAGED2_chrX_54839457_ENST00000375058_TRO_chrX_54953016_ENST00000173898_length(amino acids)=1267AA_BP=331
MSDTSESGAGLTRFQAEASEKDSSSMMQTLLTVTQNVEVPETPKASKALEVSEDVKVSKASGVSKATEVSKTPEAREAPATQASSTTQLT
DTQVLAAENKSLAADTKKQNADPQAVTMPATETKKVSHVADTKVNTKAQETEAAPSQAPADEPEPESAAAQSQENQDTRPKVKAKKARKV
KHLDGEEDGSSDQSQASGTTGGRRVSKALMASMARRASRGPIAFWARRASRTRLAAWARRALLSLRSPKARRGKARRRAAKLQSSQEPEA
PPPRDVALLQGRANDLVKYLLAKDQTKIPIKRSDMLKDIIKEYTDVYPEIIERAGYSLEKVFGIQLKEIDKNDHLYILLSTLEPTDAGIL
GTTKDSPKLGLLMVLLSIIFMNGNRSSEAVIWEVLRKLGLRPGVRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRPPEYEFFWGLRSYHE
TSKMKVLKFACRVQKKDPKDWAVQYREAVEMEVQAAAVAVAEAEARAEARAQMGIGEEAVAGPWNWDDMDIDCLTREELGDDAQAWSRFS
FEIEARAQENADASTNVNFSRGASTRAGFSDGASISFNGAPSSSGGFSGGPGITFGVAPSTSASFSNTASISFGGTLSTSSSFSSAASIS
FGCAHSTSTSFSSEASISFGGMPCTSASFSGGVSSSFSGPLSTSATFSGGASSGFGGTLSTTAGFSGVLSTSTSFGSAPTTSTVFSSALS
TSTGFGGILSTSVCFGGSPSSSGSFGGTLSTSICFGGSPCTSTGFGGTLSTSVSFGGSSSTSANFGGTLSTSICFDGSPSTGAGFGGALN
TSASFGSVLNTSTGFGGAMSTSADFGGTLSTSVCFGGSPGTSVSFGSALNTNAGYGGAVSTNTDFGGTLSTSVCFGGSPSTSAGFGGALN
TNASFGCAVSTSASFSGAVSTSACFSGAPITNPGFGGAFSTSAGFGGALSTAADFGGTPSNSIGFGAAPSTSVSFGGAHGTSLCFGGAPS
TSLCFGSASNTNLCFGGPPSTSACFSGATSPSFCDGPSTSTGFSFGNGLSTNAGFGGGLNTSAGFGGGLGTSAGFSGGLSTSSGFDGGLG
TSAGFGGGPGTSTGFGGGLGTSAGFSGGLGTSAGFGGGLVTSDGFGGGLGTNASFGSTLGTSAGFSGGLSTSDGFGSRPNASFDRGLSTI
IGFGSGSNTSTGFTGEPSTSTGFSSGPSSIVGFSGGPSTGVGFCSGPSTSGFSGGPSTGAGFGGGPNTGAGFGGGPSTSAGFGSGAASLG

--------------------------------------------------------------

>50770_50770_14_MAGED2-TRO_MAGED2_chrX_54839457_ENST00000375058_TRO_chrX_54953016_ENST00000319167_length(amino acids)=542AA_BP=271
MSDTSESGAGLTRFQAEASEKDSSSMMQTLLTVTQNVEVPETPKASKALEVSEDVKVSKASGVSKATEVSKTPEAREAPATQASSTTQLT
DTQVLAAENKSLAADTKKQNADPQAVTMPATETKKVSHVADTKVNTKAQETEAAPSQAPADEPEPESAAAQSQENQDTRPKVKAKKARKV
KHLDGEEDGSSDQSQASGTTGGRRVSKALMASMARRASRGPIAFWARRASRTRLAAWARRALLSLRSPKARRGKARRRAAKLQSSQEPEA
PPPRDVALLQGRANDLVKYLLAKDQTKIPIKRSDMLKDIIKEYTDVYPEIIERAGYSLEKVFGIQLKEIDKNDHLYILLSTLEPTDAGIL
GTTKDSPKLGLLMVLLSIIFMNGNRSSEAVIWEVLRKLGLRPGVRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRPPEYEFFWGLRSYHE
TSKMKVLKFACRVQKKDPKDWAVQYREAVEMEVQAAAVAVAEAEARAEIYSPCLQIPLINCSSPSHGAKVHPWNLCPHSSQGSYGQSAEG

--------------------------------------------------------------

>50770_50770_15_MAGED2-TRO_MAGED2_chrX_54839457_ENST00000375058_TRO_chrX_54953016_ENST00000375022_length(amino acids)=542AA_BP=271
MSDTSESGAGLTRFQAEASEKDSSSMMQTLLTVTQNVEVPETPKASKALEVSEDVKVSKASGVSKATEVSKTPEAREAPATQASSTTQLT
DTQVLAAENKSLAADTKKQNADPQAVTMPATETKKVSHVADTKVNTKAQETEAAPSQAPADEPEPESAAAQSQENQDTRPKVKAKKARKV
KHLDGEEDGSSDQSQASGTTGGRRVSKALMASMARRASRGPIAFWARRASRTRLAAWARRALLSLRSPKARRGKARRRAAKLQSSQEPEA
PPPRDVALLQGRANDLVKYLLAKDQTKIPIKRSDMLKDIIKEYTDVYPEIIERAGYSLEKVFGIQLKEIDKNDHLYILLSTLEPTDAGIL
GTTKDSPKLGLLMVLLSIIFMNGNRSSEAVIWEVLRKLGLRPGVRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRPPEYEFFWGLRSYHE
TSKMKVLKFACRVQKKDPKDWAVQYREAVEMEVQAAAVAVAEAEARAEIYSPCLQIPLINCSSPSHGAKVHPWNLCPHSSQGSYGQSAEG

--------------------------------------------------------------

>50770_50770_16_MAGED2-TRO_MAGED2_chrX_54839457_ENST00000375058_TRO_chrX_54953016_ENST00000399736_length(amino acids)=542AA_BP=271
MSDTSESGAGLTRFQAEASEKDSSSMMQTLLTVTQNVEVPETPKASKALEVSEDVKVSKASGVSKATEVSKTPEAREAPATQASSTTQLT
DTQVLAAENKSLAADTKKQNADPQAVTMPATETKKVSHVADTKVNTKAQETEAAPSQAPADEPEPESAAAQSQENQDTRPKVKAKKARKV
KHLDGEEDGSSDQSQASGTTGGRRVSKALMASMARRASRGPIAFWARRASRTRLAAWARRALLSLRSPKARRGKARRRAAKLQSSQEPEA
PPPRDVALLQGRANDLVKYLLAKDQTKIPIKRSDMLKDIIKEYTDVYPEIIERAGYSLEKVFGIQLKEIDKNDHLYILLSTLEPTDAGIL
GTTKDSPKLGLLMVLLSIIFMNGNRSSEAVIWEVLRKLGLRPGVRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRPPEYEFFWGLRSYHE
TSKMKVLKFACRVQKKDPKDWAVQYREAVEMEVQAAAVAVAEAEARAEIYSPCLQIPLINCSSPSHGAKVHPWNLCPHSSQGSYGQSAEG

--------------------------------------------------------------

>50770_50770_17_MAGED2-TRO_MAGED2_chrX_54839457_ENST00000375060_TRO_chrX_54953016_ENST00000173898_length(amino acids)=1182AA_BP=246
MSDTSESGAGLTRFQAEASEKDSSSMMQTLLTVTQNVEVPETPKASSTTQLTDTQVLAAENKSLAADTKKQNADPQAVTMPATETKKVSH
VADTKVNTKAQETEAAPSQAPADEPEPESAAAQSQENQDTRPKVKAKKARKVKHLDGEEDGSSDQSQASGTTGGRRVSKARRRAAKLQSS
QEPEAPPPRDVALLQGRANDLVKYLLAKDQTKIPIKRSDMLKDIIKEYTDVYPEIIERAGYSLEKVFGIQLKEIDKNDHLYILLSTLEPT
DAGILGTTKDSPKLGLLMVLLSIIFMNGNRSSEAVIWEVLRKLGLRPGVRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRPPEYEFFWGL
RSYHETSKMKVLKFACRVQKKDPKDWAVQYREAVEMEVQAAAVAVAEAEARAEARAQMGIGEEAVAGPWNWDDMDIDCLTREELGDDAQA
WSRFSFEIEARAQENADASTNVNFSRGASTRAGFSDGASISFNGAPSSSGGFSGGPGITFGVAPSTSASFSNTASISFGGTLSTSSSFSS
AASISFGCAHSTSTSFSSEASISFGGMPCTSASFSGGVSSSFSGPLSTSATFSGGASSGFGGTLSTTAGFSGVLSTSTSFGSAPTTSTVF
SSALSTSTGFGGILSTSVCFGGSPSSSGSFGGTLSTSICFGGSPCTSTGFGGTLSTSVSFGGSSSTSANFGGTLSTSICFDGSPSTGAGF
GGALNTSASFGSVLNTSTGFGGAMSTSADFGGTLSTSVCFGGSPGTSVSFGSALNTNAGYGGAVSTNTDFGGTLSTSVCFGGSPSTSAGF
GGALNTNASFGCAVSTSASFSGAVSTSACFSGAPITNPGFGGAFSTSAGFGGALSTAADFGGTPSNSIGFGAAPSTSVSFGGAHGTSLCF
GGAPSTSLCFGSASNTNLCFGGPPSTSACFSGATSPSFCDGPSTSTGFSFGNGLSTNAGFGGGLNTSAGFGGGLGTSAGFSGGLSTSSGF
DGGLGTSAGFGGGPGTSTGFGGGLGTSAGFSGGLGTSAGFGGGLVTSDGFGGGLGTNASFGSTLGTSAGFSGGLSTSDGFGSRPNASFDR
GLSTIIGFGSGSNTSTGFTGEPSTSTGFSSGPSSIVGFSGGPSTGVGFCSGPSTSGFSGGPSTGAGFGGGPNTGAGFGGGPSTSAGFGSG

--------------------------------------------------------------

>50770_50770_18_MAGED2-TRO_MAGED2_chrX_54839457_ENST00000375060_TRO_chrX_54953016_ENST00000319167_length(amino acids)=457AA_BP=186
MSDTSESGAGLTRFQAEASEKDSSSMMQTLLTVTQNVEVPETPKASSTTQLTDTQVLAAENKSLAADTKKQNADPQAVTMPATETKKVSH
VADTKVNTKAQETEAAPSQAPADEPEPESAAAQSQENQDTRPKVKAKKARKVKHLDGEEDGSSDQSQASGTTGGRRVSKARRRAAKLQSS
QEPEAPPPRDVALLQGRANDLVKYLLAKDQTKIPIKRSDMLKDIIKEYTDVYPEIIERAGYSLEKVFGIQLKEIDKNDHLYILLSTLEPT
DAGILGTTKDSPKLGLLMVLLSIIFMNGNRSSEAVIWEVLRKLGLRPGVRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRPPEYEFFWGL
RSYHETSKMKVLKFACRVQKKDPKDWAVQYREAVEMEVQAAAVAVAEAEARAEIYSPCLQIPLINCSSPSHGAKVHPWNLCPHSSQGSYG

--------------------------------------------------------------

>50770_50770_19_MAGED2-TRO_MAGED2_chrX_54839457_ENST00000375060_TRO_chrX_54953016_ENST00000375022_length(amino acids)=457AA_BP=186
MSDTSESGAGLTRFQAEASEKDSSSMMQTLLTVTQNVEVPETPKASSTTQLTDTQVLAAENKSLAADTKKQNADPQAVTMPATETKKVSH
VADTKVNTKAQETEAAPSQAPADEPEPESAAAQSQENQDTRPKVKAKKARKVKHLDGEEDGSSDQSQASGTTGGRRVSKARRRAAKLQSS
QEPEAPPPRDVALLQGRANDLVKYLLAKDQTKIPIKRSDMLKDIIKEYTDVYPEIIERAGYSLEKVFGIQLKEIDKNDHLYILLSTLEPT
DAGILGTTKDSPKLGLLMVLLSIIFMNGNRSSEAVIWEVLRKLGLRPGVRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRPPEYEFFWGL
RSYHETSKMKVLKFACRVQKKDPKDWAVQYREAVEMEVQAAAVAVAEAEARAEIYSPCLQIPLINCSSPSHGAKVHPWNLCPHSSQGSYG

--------------------------------------------------------------

>50770_50770_20_MAGED2-TRO_MAGED2_chrX_54839457_ENST00000375060_TRO_chrX_54953016_ENST00000399736_length(amino acids)=457AA_BP=186
MSDTSESGAGLTRFQAEASEKDSSSMMQTLLTVTQNVEVPETPKASSTTQLTDTQVLAAENKSLAADTKKQNADPQAVTMPATETKKVSH
VADTKVNTKAQETEAAPSQAPADEPEPESAAAQSQENQDTRPKVKAKKARKVKHLDGEEDGSSDQSQASGTTGGRRVSKARRRAAKLQSS
QEPEAPPPRDVALLQGRANDLVKYLLAKDQTKIPIKRSDMLKDIIKEYTDVYPEIIERAGYSLEKVFGIQLKEIDKNDHLYILLSTLEPT
DAGILGTTKDSPKLGLLMVLLSIIFMNGNRSSEAVIWEVLRKLGLRPGVRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRPPEYEFFWGL
RSYHETSKMKVLKFACRVQKKDPKDWAVQYREAVEMEVQAAAVAVAEAEARAEIYSPCLQIPLINCSSPSHGAKVHPWNLCPHSSQGSYG

--------------------------------------------------------------

>50770_50770_21_MAGED2-TRO_MAGED2_chrX_54839457_ENST00000375062_TRO_chrX_54953016_ENST00000173898_length(amino acids)=1182AA_BP=246
MSDTSESGAGLTRFQAEASEKDSSSMMQTLLTVTQNVEVPETPKASSTTQLTDTQVLAAENKSLAADTKKQNADPQAVTMPATETKKVSH
VADTKVNTKAQETEAAPSQAPADEPEPESAAAQSQENQDTRPKVKAKKARKVKHLDGEEDGSSDQSQASGTTGGRRVSKARRRAAKLQSS
QEPEAPPPRDVALLQGRANDLVKYLLAKDQTKIPIKRSDMLKDIIKEYTDVYPEIIERAGYSLEKVFGIQLKEIDKNDHLYILLSTLEPT
DAGILGTTKDSPKLGLLMVLLSIIFMNGNRSSEAVIWEVLRKLGLRPGVRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRPPEYEFFWGL
RSYHETSKMKVLKFACRVQKKDPKDWAVQYREAVEMEVQAAAVAVAEAEARAEARAQMGIGEEAVAGPWNWDDMDIDCLTREELGDDAQA
WSRFSFEIEARAQENADASTNVNFSRGASTRAGFSDGASISFNGAPSSSGGFSGGPGITFGVAPSTSASFSNTASISFGGTLSTSSSFSS
AASISFGCAHSTSTSFSSEASISFGGMPCTSASFSGGVSSSFSGPLSTSATFSGGASSGFGGTLSTTAGFSGVLSTSTSFGSAPTTSTVF
SSALSTSTGFGGILSTSVCFGGSPSSSGSFGGTLSTSICFGGSPCTSTGFGGTLSTSVSFGGSSSTSANFGGTLSTSICFDGSPSTGAGF
GGALNTSASFGSVLNTSTGFGGAMSTSADFGGTLSTSVCFGGSPGTSVSFGSALNTNAGYGGAVSTNTDFGGTLSTSVCFGGSPSTSAGF
GGALNTNASFGCAVSTSASFSGAVSTSACFSGAPITNPGFGGAFSTSAGFGGALSTAADFGGTPSNSIGFGAAPSTSVSFGGAHGTSLCF
GGAPSTSLCFGSASNTNLCFGGPPSTSACFSGATSPSFCDGPSTSTGFSFGNGLSTNAGFGGGLNTSAGFGGGLGTSAGFSGGLSTSSGF
DGGLGTSAGFGGGPGTSTGFGGGLGTSAGFSGGLGTSAGFGGGLVTSDGFGGGLGTNASFGSTLGTSAGFSGGLSTSDGFGSRPNASFDR
GLSTIIGFGSGSNTSTGFTGEPSTSTGFSSGPSSIVGFSGGPSTGVGFCSGPSTSGFSGGPSTGAGFGGGPNTGAGFGGGPSTSAGFGSG

--------------------------------------------------------------

>50770_50770_22_MAGED2-TRO_MAGED2_chrX_54839457_ENST00000375062_TRO_chrX_54953016_ENST00000319167_length(amino acids)=457AA_BP=186
MSDTSESGAGLTRFQAEASEKDSSSMMQTLLTVTQNVEVPETPKASSTTQLTDTQVLAAENKSLAADTKKQNADPQAVTMPATETKKVSH
VADTKVNTKAQETEAAPSQAPADEPEPESAAAQSQENQDTRPKVKAKKARKVKHLDGEEDGSSDQSQASGTTGGRRVSKARRRAAKLQSS
QEPEAPPPRDVALLQGRANDLVKYLLAKDQTKIPIKRSDMLKDIIKEYTDVYPEIIERAGYSLEKVFGIQLKEIDKNDHLYILLSTLEPT
DAGILGTTKDSPKLGLLMVLLSIIFMNGNRSSEAVIWEVLRKLGLRPGVRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRPPEYEFFWGL
RSYHETSKMKVLKFACRVQKKDPKDWAVQYREAVEMEVQAAAVAVAEAEARAEIYSPCLQIPLINCSSPSHGAKVHPWNLCPHSSQGSYG

--------------------------------------------------------------

>50770_50770_23_MAGED2-TRO_MAGED2_chrX_54839457_ENST00000375062_TRO_chrX_54953016_ENST00000375022_length(amino acids)=457AA_BP=186
MSDTSESGAGLTRFQAEASEKDSSSMMQTLLTVTQNVEVPETPKASSTTQLTDTQVLAAENKSLAADTKKQNADPQAVTMPATETKKVSH
VADTKVNTKAQETEAAPSQAPADEPEPESAAAQSQENQDTRPKVKAKKARKVKHLDGEEDGSSDQSQASGTTGGRRVSKARRRAAKLQSS
QEPEAPPPRDVALLQGRANDLVKYLLAKDQTKIPIKRSDMLKDIIKEYTDVYPEIIERAGYSLEKVFGIQLKEIDKNDHLYILLSTLEPT
DAGILGTTKDSPKLGLLMVLLSIIFMNGNRSSEAVIWEVLRKLGLRPGVRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRPPEYEFFWGL
RSYHETSKMKVLKFACRVQKKDPKDWAVQYREAVEMEVQAAAVAVAEAEARAEIYSPCLQIPLINCSSPSHGAKVHPWNLCPHSSQGSYG

--------------------------------------------------------------

>50770_50770_24_MAGED2-TRO_MAGED2_chrX_54839457_ENST00000375062_TRO_chrX_54953016_ENST00000399736_length(amino acids)=457AA_BP=186
MSDTSESGAGLTRFQAEASEKDSSSMMQTLLTVTQNVEVPETPKASSTTQLTDTQVLAAENKSLAADTKKQNADPQAVTMPATETKKVSH
VADTKVNTKAQETEAAPSQAPADEPEPESAAAQSQENQDTRPKVKAKKARKVKHLDGEEDGSSDQSQASGTTGGRRVSKARRRAAKLQSS
QEPEAPPPRDVALLQGRANDLVKYLLAKDQTKIPIKRSDMLKDIIKEYTDVYPEIIERAGYSLEKVFGIQLKEIDKNDHLYILLSTLEPT
DAGILGTTKDSPKLGLLMVLLSIIFMNGNRSSEAVIWEVLRKLGLRPGVRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRPPEYEFFWGL
RSYHETSKMKVLKFACRVQKKDPKDWAVQYREAVEMEVQAAAVAVAEAEARAEIYSPCLQIPLINCSSPSHGAKVHPWNLCPHSSQGSYG

--------------------------------------------------------------

>50770_50770_25_MAGED2-TRO_MAGED2_chrX_54839457_ENST00000375068_TRO_chrX_54953016_ENST00000173898_length(amino acids)=1267AA_BP=331
MSDTSESGAGLTRFQAEASEKDSSSMMQTLLTVTQNVEVPETPKASKALEVSEDVKVSKASGVSKATEVSKTPEAREAPATQASSTTQLT
DTQVLAAENKSLAADTKKQNADPQAVTMPATETKKVSHVADTKVNTKAQETEAAPSQAPADEPEPESAAAQSQENQDTRPKVKAKKARKV
KHLDGEEDGSSDQSQASGTTGGRRVSKALMASMARRASRGPIAFWARRASRTRLAAWARRALLSLRSPKARRGKARRRAAKLQSSQEPEA
PPPRDVALLQGRANDLVKYLLAKDQTKIPIKRSDMLKDIIKEYTDVYPEIIERAGYSLEKVFGIQLKEIDKNDHLYILLSTLEPTDAGIL
GTTKDSPKLGLLMVLLSIIFMNGNRSSEAVIWEVLRKLGLRPGVRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRPPEYEFFWGLRSYHE
TSKMKVLKFACRVQKKDPKDWAVQYREAVEMEVQAAAVAVAEAEARAEARAQMGIGEEAVAGPWNWDDMDIDCLTREELGDDAQAWSRFS
FEIEARAQENADASTNVNFSRGASTRAGFSDGASISFNGAPSSSGGFSGGPGITFGVAPSTSASFSNTASISFGGTLSTSSSFSSAASIS
FGCAHSTSTSFSSEASISFGGMPCTSASFSGGVSSSFSGPLSTSATFSGGASSGFGGTLSTTAGFSGVLSTSTSFGSAPTTSTVFSSALS
TSTGFGGILSTSVCFGGSPSSSGSFGGTLSTSICFGGSPCTSTGFGGTLSTSVSFGGSSSTSANFGGTLSTSICFDGSPSTGAGFGGALN
TSASFGSVLNTSTGFGGAMSTSADFGGTLSTSVCFGGSPGTSVSFGSALNTNAGYGGAVSTNTDFGGTLSTSVCFGGSPSTSAGFGGALN
TNASFGCAVSTSASFSGAVSTSACFSGAPITNPGFGGAFSTSAGFGGALSTAADFGGTPSNSIGFGAAPSTSVSFGGAHGTSLCFGGAPS
TSLCFGSASNTNLCFGGPPSTSACFSGATSPSFCDGPSTSTGFSFGNGLSTNAGFGGGLNTSAGFGGGLGTSAGFSGGLSTSSGFDGGLG
TSAGFGGGPGTSTGFGGGLGTSAGFSGGLGTSAGFGGGLVTSDGFGGGLGTNASFGSTLGTSAGFSGGLSTSDGFGSRPNASFDRGLSTI
IGFGSGSNTSTGFTGEPSTSTGFSSGPSSIVGFSGGPSTGVGFCSGPSTSGFSGGPSTGAGFGGGPNTGAGFGGGPSTSAGFGSGAASLG

--------------------------------------------------------------

>50770_50770_26_MAGED2-TRO_MAGED2_chrX_54839457_ENST00000375068_TRO_chrX_54953016_ENST00000319167_length(amino acids)=542AA_BP=271
MSDTSESGAGLTRFQAEASEKDSSSMMQTLLTVTQNVEVPETPKASKALEVSEDVKVSKASGVSKATEVSKTPEAREAPATQASSTTQLT
DTQVLAAENKSLAADTKKQNADPQAVTMPATETKKVSHVADTKVNTKAQETEAAPSQAPADEPEPESAAAQSQENQDTRPKVKAKKARKV
KHLDGEEDGSSDQSQASGTTGGRRVSKALMASMARRASRGPIAFWARRASRTRLAAWARRALLSLRSPKARRGKARRRAAKLQSSQEPEA
PPPRDVALLQGRANDLVKYLLAKDQTKIPIKRSDMLKDIIKEYTDVYPEIIERAGYSLEKVFGIQLKEIDKNDHLYILLSTLEPTDAGIL
GTTKDSPKLGLLMVLLSIIFMNGNRSSEAVIWEVLRKLGLRPGVRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRPPEYEFFWGLRSYHE
TSKMKVLKFACRVQKKDPKDWAVQYREAVEMEVQAAAVAVAEAEARAEIYSPCLQIPLINCSSPSHGAKVHPWNLCPHSSQGSYGQSAEG

--------------------------------------------------------------

>50770_50770_27_MAGED2-TRO_MAGED2_chrX_54839457_ENST00000375068_TRO_chrX_54953016_ENST00000375022_length(amino acids)=542AA_BP=271
MSDTSESGAGLTRFQAEASEKDSSSMMQTLLTVTQNVEVPETPKASKALEVSEDVKVSKASGVSKATEVSKTPEAREAPATQASSTTQLT
DTQVLAAENKSLAADTKKQNADPQAVTMPATETKKVSHVADTKVNTKAQETEAAPSQAPADEPEPESAAAQSQENQDTRPKVKAKKARKV
KHLDGEEDGSSDQSQASGTTGGRRVSKALMASMARRASRGPIAFWARRASRTRLAAWARRALLSLRSPKARRGKARRRAAKLQSSQEPEA
PPPRDVALLQGRANDLVKYLLAKDQTKIPIKRSDMLKDIIKEYTDVYPEIIERAGYSLEKVFGIQLKEIDKNDHLYILLSTLEPTDAGIL
GTTKDSPKLGLLMVLLSIIFMNGNRSSEAVIWEVLRKLGLRPGVRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRPPEYEFFWGLRSYHE
TSKMKVLKFACRVQKKDPKDWAVQYREAVEMEVQAAAVAVAEAEARAEIYSPCLQIPLINCSSPSHGAKVHPWNLCPHSSQGSYGQSAEG

--------------------------------------------------------------

>50770_50770_28_MAGED2-TRO_MAGED2_chrX_54839457_ENST00000375068_TRO_chrX_54953016_ENST00000399736_length(amino acids)=542AA_BP=271
MSDTSESGAGLTRFQAEASEKDSSSMMQTLLTVTQNVEVPETPKASKALEVSEDVKVSKASGVSKATEVSKTPEAREAPATQASSTTQLT
DTQVLAAENKSLAADTKKQNADPQAVTMPATETKKVSHVADTKVNTKAQETEAAPSQAPADEPEPESAAAQSQENQDTRPKVKAKKARKV
KHLDGEEDGSSDQSQASGTTGGRRVSKALMASMARRASRGPIAFWARRASRTRLAAWARRALLSLRSPKARRGKARRRAAKLQSSQEPEA
PPPRDVALLQGRANDLVKYLLAKDQTKIPIKRSDMLKDIIKEYTDVYPEIIERAGYSLEKVFGIQLKEIDKNDHLYILLSTLEPTDAGIL
GTTKDSPKLGLLMVLLSIIFMNGNRSSEAVIWEVLRKLGLRPGVRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRPPEYEFFWGLRSYHE
TSKMKVLKFACRVQKKDPKDWAVQYREAVEMEVQAAAVAVAEAEARAEIYSPCLQIPLINCSSPSHGAKVHPWNLCPHSSQGSYGQSAEG

--------------------------------------------------------------

>50770_50770_29_MAGED2-TRO_MAGED2_chrX_54839457_ENST00000396224_TRO_chrX_54953016_ENST00000173898_length(amino acids)=1267AA_BP=331
MSDTSESGAGLTRFQAEASEKDSSSMMQTLLTVTQNVEVPETPKASKALEVSEDVKVSKASGVSKATEVSKTPEAREAPATQASSTTQLT
DTQVLAAENKSLAADTKKQNADPQAVTMPATETKKVSHVADTKVNTKAQETEAAPSQAPADEPEPESAAAQSQENQDTRPKVKAKKARKV
KHLDGEEDGSSDQSQASGTTGGRRVSKALMASMARRASRGPIAFWARRASRTRLAAWARRALLSLRSPKARRGKARRRAAKLQSSQEPEA
PPPRDVALLQGRANDLVKYLLAKDQTKIPIKRSDMLKDIIKEYTDVYPEIIERAGYSLEKVFGIQLKEIDKNDHLYILLSTLEPTDAGIL
GTTKDSPKLGLLMVLLSIIFMNGNRSSEAVIWEVLRKLGLRPGVRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRPPEYEFFWGLRSYHE
TSKMKVLKFACRVQKKDPKDWAVQYREAVEMEVQAAAVAVAEAEARAEARAQMGIGEEAVAGPWNWDDMDIDCLTREELGDDAQAWSRFS
FEIEARAQENADASTNVNFSRGASTRAGFSDGASISFNGAPSSSGGFSGGPGITFGVAPSTSASFSNTASISFGGTLSTSSSFSSAASIS
FGCAHSTSTSFSSEASISFGGMPCTSASFSGGVSSSFSGPLSTSATFSGGASSGFGGTLSTTAGFSGVLSTSTSFGSAPTTSTVFSSALS
TSTGFGGILSTSVCFGGSPSSSGSFGGTLSTSICFGGSPCTSTGFGGTLSTSVSFGGSSSTSANFGGTLSTSICFDGSPSTGAGFGGALN
TSASFGSVLNTSTGFGGAMSTSADFGGTLSTSVCFGGSPGTSVSFGSALNTNAGYGGAVSTNTDFGGTLSTSVCFGGSPSTSAGFGGALN
TNASFGCAVSTSASFSGAVSTSACFSGAPITNPGFGGAFSTSAGFGGALSTAADFGGTPSNSIGFGAAPSTSVSFGGAHGTSLCFGGAPS
TSLCFGSASNTNLCFGGPPSTSACFSGATSPSFCDGPSTSTGFSFGNGLSTNAGFGGGLNTSAGFGGGLGTSAGFSGGLSTSSGFDGGLG
TSAGFGGGPGTSTGFGGGLGTSAGFSGGLGTSAGFGGGLVTSDGFGGGLGTNASFGSTLGTSAGFSGGLSTSDGFGSRPNASFDRGLSTI
IGFGSGSNTSTGFTGEPSTSTGFSSGPSSIVGFSGGPSTGVGFCSGPSTSGFSGGPSTGAGFGGGPNTGAGFGGGPSTSAGFGSGAASLG

--------------------------------------------------------------

>50770_50770_30_MAGED2-TRO_MAGED2_chrX_54839457_ENST00000396224_TRO_chrX_54953016_ENST00000319167_length(amino acids)=542AA_BP=271
MSDTSESGAGLTRFQAEASEKDSSSMMQTLLTVTQNVEVPETPKASKALEVSEDVKVSKASGVSKATEVSKTPEAREAPATQASSTTQLT
DTQVLAAENKSLAADTKKQNADPQAVTMPATETKKVSHVADTKVNTKAQETEAAPSQAPADEPEPESAAAQSQENQDTRPKVKAKKARKV
KHLDGEEDGSSDQSQASGTTGGRRVSKALMASMARRASRGPIAFWARRASRTRLAAWARRALLSLRSPKARRGKARRRAAKLQSSQEPEA
PPPRDVALLQGRANDLVKYLLAKDQTKIPIKRSDMLKDIIKEYTDVYPEIIERAGYSLEKVFGIQLKEIDKNDHLYILLSTLEPTDAGIL
GTTKDSPKLGLLMVLLSIIFMNGNRSSEAVIWEVLRKLGLRPGVRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRPPEYEFFWGLRSYHE
TSKMKVLKFACRVQKKDPKDWAVQYREAVEMEVQAAAVAVAEAEARAEIYSPCLQIPLINCSSPSHGAKVHPWNLCPHSSQGSYGQSAEG

--------------------------------------------------------------

>50770_50770_31_MAGED2-TRO_MAGED2_chrX_54839457_ENST00000396224_TRO_chrX_54953016_ENST00000375022_length(amino acids)=542AA_BP=271
MSDTSESGAGLTRFQAEASEKDSSSMMQTLLTVTQNVEVPETPKASKALEVSEDVKVSKASGVSKATEVSKTPEAREAPATQASSTTQLT
DTQVLAAENKSLAADTKKQNADPQAVTMPATETKKVSHVADTKVNTKAQETEAAPSQAPADEPEPESAAAQSQENQDTRPKVKAKKARKV
KHLDGEEDGSSDQSQASGTTGGRRVSKALMASMARRASRGPIAFWARRASRTRLAAWARRALLSLRSPKARRGKARRRAAKLQSSQEPEA
PPPRDVALLQGRANDLVKYLLAKDQTKIPIKRSDMLKDIIKEYTDVYPEIIERAGYSLEKVFGIQLKEIDKNDHLYILLSTLEPTDAGIL
GTTKDSPKLGLLMVLLSIIFMNGNRSSEAVIWEVLRKLGLRPGVRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRPPEYEFFWGLRSYHE
TSKMKVLKFACRVQKKDPKDWAVQYREAVEMEVQAAAVAVAEAEARAEIYSPCLQIPLINCSSPSHGAKVHPWNLCPHSSQGSYGQSAEG

--------------------------------------------------------------

>50770_50770_32_MAGED2-TRO_MAGED2_chrX_54839457_ENST00000396224_TRO_chrX_54953016_ENST00000399736_length(amino acids)=542AA_BP=271
MSDTSESGAGLTRFQAEASEKDSSSMMQTLLTVTQNVEVPETPKASKALEVSEDVKVSKASGVSKATEVSKTPEAREAPATQASSTTQLT
DTQVLAAENKSLAADTKKQNADPQAVTMPATETKKVSHVADTKVNTKAQETEAAPSQAPADEPEPESAAAQSQENQDTRPKVKAKKARKV
KHLDGEEDGSSDQSQASGTTGGRRVSKALMASMARRASRGPIAFWARRASRTRLAAWARRALLSLRSPKARRGKARRRAAKLQSSQEPEA
PPPRDVALLQGRANDLVKYLLAKDQTKIPIKRSDMLKDIIKEYTDVYPEIIERAGYSLEKVFGIQLKEIDKNDHLYILLSTLEPTDAGIL
GTTKDSPKLGLLMVLLSIIFMNGNRSSEAVIWEVLRKLGLRPGVRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRPPEYEFFWGLRSYHE
TSKMKVLKFACRVQKKDPKDWAVQYREAVEMEVQAAAVAVAEAEARAEIYSPCLQIPLINCSSPSHGAKVHPWNLCPHSSQGSYGQSAEG

--------------------------------------------------------------

Top

Fusion Protein Functional Features


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chrX:54953058/chrX:54839921)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
MAGED2

Q9UNF1

TRO

TNNT1

FUNCTION: Regulates the expression, localization to the plasma membrane and function of the sodium chloride cotransporters SLC12A1 and SLC12A3, two key components of salt reabsorption in the distal renal tubule. {ECO:0000269|PubMed:27120771}.278

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

* Minus value of BPloci means that the break pointn is located before the CDS.
- Retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneMAGED2chrX:54839457chrX:54953016ENST00000218439+812215_258388.3333333333333607.0Compositional biasNote=Arg-rich
HgeneMAGED2chrX:54839457chrX:54953016ENST00000375053+812215_258388.3333333333333607.0Compositional biasNote=Arg-rich
HgeneMAGED2chrX:54839457chrX:54953016ENST00000375058+813215_258388.3333333333333628.3333333333334Compositional biasNote=Arg-rich
HgeneMAGED2chrX:54839457chrX:54953016ENST00000375068+813215_258388.3333333333333581.3333333333334Compositional biasNote=Arg-rich
HgeneMAGED2chrX:54839457chrX:54953016ENST00000396224+812215_258388.3333333333333607.0Compositional biasNote=Arg-rich
TgeneTROchrX:54839457chrX:54953016ENST00000173898713751_1430552.33333333333341485.3333333333333RegionNote=62 X 10 AA approximate tandem repeats
TgeneTROchrX:54839457chrX:54953016ENST00000319167713751_1430552.3333333333334707.0RegionNote=62 X 10 AA approximate tandem repeats
TgeneTROchrX:54839457chrX:54953016ENST00000375022713751_1430552.3333333333334707.0RegionNote=62 X 10 AA approximate tandem repeats
TgeneTROchrX:54839457chrX:54953016ENST000001738987131001_1010552.33333333333341485.3333333333333RepeatNote=20
TgeneTROchrX:54839457chrX:54953016ENST000001738987131011_1020552.33333333333341485.3333333333333RepeatNote=21
TgeneTROchrX:54839457chrX:54953016ENST000001738987131021_1030552.33333333333341485.3333333333333RepeatNote=22%3B approximate
TgeneTROchrX:54839457chrX:54953016ENST000001738987131031_1040552.33333333333341485.3333333333333RepeatNote=23
TgeneTROchrX:54839457chrX:54953016ENST000001738987131041_1050552.33333333333341485.3333333333333RepeatNote=24
TgeneTROchrX:54839457chrX:54953016ENST000001738987131051_1060552.33333333333341485.3333333333333RepeatNote=25
TgeneTROchrX:54839457chrX:54953016ENST000001738987131061_1070552.33333333333341485.3333333333333RepeatNote=26
TgeneTROchrX:54839457chrX:54953016ENST000001738987131071_1080552.33333333333341485.3333333333333RepeatNote=27%3B approximate
TgeneTROchrX:54839457chrX:54953016ENST000001738987131081_1090552.33333333333341485.3333333333333RepeatNote=28%3B approximate
TgeneTROchrX:54839457chrX:54953016ENST000001738987131091_1100552.33333333333341485.3333333333333RepeatNote=29
TgeneTROchrX:54839457chrX:54953016ENST000001738987131101_1110552.33333333333341485.3333333333333RepeatNote=30
TgeneTROchrX:54839457chrX:54953016ENST000001738987131111_1120552.33333333333341485.3333333333333RepeatNote=31
TgeneTROchrX:54839457chrX:54953016ENST000001738987131121_1130552.33333333333341485.3333333333333RepeatNote=32
TgeneTROchrX:54839457chrX:54953016ENST000001738987131131_1140552.33333333333341485.3333333333333RepeatNote=33
TgeneTROchrX:54839457chrX:54953016ENST000001738987131141_1150552.33333333333341485.3333333333333RepeatNote=34
TgeneTROchrX:54839457chrX:54953016ENST000001738987131151_1160552.33333333333341485.3333333333333RepeatNote=35
TgeneTROchrX:54839457chrX:54953016ENST000001738987131161_1170552.33333333333341485.3333333333333RepeatNote=36
TgeneTROchrX:54839457chrX:54953016ENST000001738987131171_1180552.33333333333341485.3333333333333RepeatNote=37%3B approximate
TgeneTROchrX:54839457chrX:54953016ENST000001738987131181_1190552.33333333333341485.3333333333333RepeatNote=38%3B approximate
TgeneTROchrX:54839457chrX:54953016ENST000001738987131191_1200552.33333333333341485.3333333333333RepeatNote=39
TgeneTROchrX:54839457chrX:54953016ENST000001738987131201_1210552.33333333333341485.3333333333333RepeatNote=40
TgeneTROchrX:54839457chrX:54953016ENST000001738987131211_1220552.33333333333341485.3333333333333RepeatNote=41
TgeneTROchrX:54839457chrX:54953016ENST000001738987131221_1230552.33333333333341485.3333333333333RepeatNote=42%3B approximate
TgeneTROchrX:54839457chrX:54953016ENST000001738987131231_1240552.33333333333341485.3333333333333RepeatNote=43%3B approximate
TgeneTROchrX:54839457chrX:54953016ENST000001738987131241_1250552.33333333333341485.3333333333333RepeatNote=44
TgeneTROchrX:54839457chrX:54953016ENST000001738987131251_1260552.33333333333341485.3333333333333RepeatNote=45
TgeneTROchrX:54839457chrX:54953016ENST000001738987131261_1270552.33333333333341485.3333333333333RepeatNote=46%3B approximate
TgeneTROchrX:54839457chrX:54953016ENST000001738987131271_1280552.33333333333341485.3333333333333RepeatNote=47
TgeneTROchrX:54839457chrX:54953016ENST000001738987131281_1290552.33333333333341485.3333333333333RepeatNote=48
TgeneTROchrX:54839457chrX:54953016ENST000001738987131291_1300552.33333333333341485.3333333333333RepeatNote=49
TgeneTROchrX:54839457chrX:54953016ENST000001738987131301_1310552.33333333333341485.3333333333333RepeatNote=50%3B approximate
TgeneTROchrX:54839457chrX:54953016ENST000001738987131311_1320552.33333333333341485.3333333333333RepeatNote=51
TgeneTROchrX:54839457chrX:54953016ENST000001738987131321_1330552.33333333333341485.3333333333333RepeatNote=52%3B approximate
TgeneTROchrX:54839457chrX:54953016ENST000001738987131331_1340552.33333333333341485.3333333333333RepeatNote=53%3B approximate
TgeneTROchrX:54839457chrX:54953016ENST000001738987131341_1350552.33333333333341485.3333333333333RepeatNote=54%3B approximate
TgeneTROchrX:54839457chrX:54953016ENST000001738987131351_1360552.33333333333341485.3333333333333RepeatNote=55%3B approximate
TgeneTROchrX:54839457chrX:54953016ENST000001738987131361_1370552.33333333333341485.3333333333333RepeatNote=56%3B approximate
TgeneTROchrX:54839457chrX:54953016ENST000001738987131371_1380552.33333333333341485.3333333333333RepeatNote=57%3B approximate
TgeneTROchrX:54839457chrX:54953016ENST000001738987131381_1390552.33333333333341485.3333333333333RepeatNote=58%3B approximate
TgeneTROchrX:54839457chrX:54953016ENST000001738987131391_1400552.33333333333341485.3333333333333RepeatNote=59%3B approximate
TgeneTROchrX:54839457chrX:54953016ENST000001738987131401_1410552.33333333333341485.3333333333333RepeatNote=60%3B approximate
TgeneTROchrX:54839457chrX:54953016ENST000001738987131411_1420552.33333333333341485.3333333333333RepeatNote=61%3B approximate
TgeneTROchrX:54839457chrX:54953016ENST000001738987131421_1430552.33333333333341485.3333333333333RepeatNote=62%3B approximate
TgeneTROchrX:54839457chrX:54953016ENST00000173898713751_760552.33333333333341485.3333333333333RepeatNote=1
TgeneTROchrX:54839457chrX:54953016ENST00000173898713769_778552.33333333333341485.3333333333333RepeatNote=2
TgeneTROchrX:54839457chrX:54953016ENST00000173898713779_786552.33333333333341485.3333333333333RepeatNote=3%3B approximate
TgeneTROchrX:54839457chrX:54953016ENST00000173898713787_796552.33333333333341485.3333333333333RepeatNote=4
TgeneTROchrX:54839457chrX:54953016ENST00000173898713805_814552.33333333333341485.3333333333333RepeatNote=5
TgeneTROchrX:54839457chrX:54953016ENST00000173898713823_833552.33333333333341485.3333333333333RepeatNote=6%3B approximate
TgeneTROchrX:54839457chrX:54953016ENST00000173898713841_850552.33333333333341485.3333333333333RepeatNote=7
TgeneTROchrX:54839457chrX:54953016ENST00000173898713859_870552.33333333333341485.3333333333333RepeatNote=8%3B approximate
TgeneTROchrX:54839457chrX:54953016ENST00000173898713879_890552.33333333333341485.3333333333333RepeatNote=9%3B approximate
TgeneTROchrX:54839457chrX:54953016ENST00000173898713901_910552.33333333333341485.3333333333333RepeatNote=10
TgeneTROchrX:54839457chrX:54953016ENST00000173898713911_920552.33333333333341485.3333333333333RepeatNote=11
TgeneTROchrX:54839457chrX:54953016ENST00000173898713921_930552.33333333333341485.3333333333333RepeatNote=12
TgeneTROchrX:54839457chrX:54953016ENST00000173898713931_940552.33333333333341485.3333333333333RepeatNote=13
TgeneTROchrX:54839457chrX:54953016ENST00000173898713941_950552.33333333333341485.3333333333333RepeatNote=14
TgeneTROchrX:54839457chrX:54953016ENST00000173898713951_960552.33333333333341485.3333333333333RepeatNote=15%3B approximate
TgeneTROchrX:54839457chrX:54953016ENST00000173898713961_970552.33333333333341485.3333333333333RepeatNote=16
TgeneTROchrX:54839457chrX:54953016ENST00000173898713971_980552.33333333333341485.3333333333333RepeatNote=17
TgeneTROchrX:54839457chrX:54953016ENST00000173898713981_990552.33333333333341485.3333333333333RepeatNote=18
TgeneTROchrX:54839457chrX:54953016ENST00000173898713991_1000552.33333333333341485.3333333333333RepeatNote=19
TgeneTROchrX:54839457chrX:54953016ENST000003191677131001_1010552.3333333333334707.0RepeatNote=20
TgeneTROchrX:54839457chrX:54953016ENST000003191677131011_1020552.3333333333334707.0RepeatNote=21
TgeneTROchrX:54839457chrX:54953016ENST000003191677131021_1030552.3333333333334707.0RepeatNote=22%3B approximate
TgeneTROchrX:54839457chrX:54953016ENST000003191677131031_1040552.3333333333334707.0RepeatNote=23
TgeneTROchrX:54839457chrX:54953016ENST000003191677131041_1050552.3333333333334707.0RepeatNote=24
TgeneTROchrX:54839457chrX:54953016ENST000003191677131051_1060552.3333333333334707.0RepeatNote=25
TgeneTROchrX:54839457chrX:54953016ENST000003191677131061_1070552.3333333333334707.0RepeatNote=26
TgeneTROchrX:54839457chrX:54953016ENST000003191677131071_1080552.3333333333334707.0RepeatNote=27%3B approximate
TgeneTROchrX:54839457chrX:54953016ENST000003191677131081_1090552.3333333333334707.0RepeatNote=28%3B approximate
TgeneTROchrX:54839457chrX:54953016ENST000003191677131091_1100552.3333333333334707.0RepeatNote=29
TgeneTROchrX:54839457chrX:54953016ENST000003191677131101_1110552.3333333333334707.0RepeatNote=30
TgeneTROchrX:54839457chrX:54953016ENST000003191677131111_1120552.3333333333334707.0RepeatNote=31
TgeneTROchrX:54839457chrX:54953016ENST000003191677131121_1130552.3333333333334707.0RepeatNote=32
TgeneTROchrX:54839457chrX:54953016ENST000003191677131131_1140552.3333333333334707.0RepeatNote=33
TgeneTROchrX:54839457chrX:54953016ENST000003191677131141_1150552.3333333333334707.0RepeatNote=34
TgeneTROchrX:54839457chrX:54953016ENST000003191677131151_1160552.3333333333334707.0RepeatNote=35
TgeneTROchrX:54839457chrX:54953016ENST000003191677131161_1170552.3333333333334707.0RepeatNote=36
TgeneTROchrX:54839457chrX:54953016ENST000003191677131171_1180552.3333333333334707.0RepeatNote=37%3B approximate
TgeneTROchrX:54839457chrX:54953016ENST000003191677131181_1190552.3333333333334707.0RepeatNote=38%3B approximate
TgeneTROchrX:54839457chrX:54953016ENST000003191677131191_1200552.3333333333334707.0RepeatNote=39
TgeneTROchrX:54839457chrX:54953016ENST000003191677131201_1210552.3333333333334707.0RepeatNote=40
TgeneTROchrX:54839457chrX:54953016ENST000003191677131211_1220552.3333333333334707.0RepeatNote=41
TgeneTROchrX:54839457chrX:54953016ENST000003191677131221_1230552.3333333333334707.0RepeatNote=42%3B approximate
TgeneTROchrX:54839457chrX:54953016ENST000003191677131231_1240552.3333333333334707.0RepeatNote=43%3B approximate
TgeneTROchrX:54839457chrX:54953016ENST000003191677131241_1250552.3333333333334707.0RepeatNote=44
TgeneTROchrX:54839457chrX:54953016ENST000003191677131251_1260552.3333333333334707.0RepeatNote=45
TgeneTROchrX:54839457chrX:54953016ENST000003191677131261_1270552.3333333333334707.0RepeatNote=46%3B approximate
TgeneTROchrX:54839457chrX:54953016ENST000003191677131271_1280552.3333333333334707.0RepeatNote=47
TgeneTROchrX:54839457chrX:54953016ENST000003191677131281_1290552.3333333333334707.0RepeatNote=48
TgeneTROchrX:54839457chrX:54953016ENST000003191677131291_1300552.3333333333334707.0RepeatNote=49
TgeneTROchrX:54839457chrX:54953016ENST000003191677131301_1310552.3333333333334707.0RepeatNote=50%3B approximate
TgeneTROchrX:54839457chrX:54953016ENST000003191677131311_1320552.3333333333334707.0RepeatNote=51
TgeneTROchrX:54839457chrX:54953016ENST000003191677131321_1330552.3333333333334707.0RepeatNote=52%3B approximate
TgeneTROchrX:54839457chrX:54953016ENST000003191677131331_1340552.3333333333334707.0RepeatNote=53%3B approximate
TgeneTROchrX:54839457chrX:54953016ENST000003191677131341_1350552.3333333333334707.0RepeatNote=54%3B approximate
TgeneTROchrX:54839457chrX:54953016ENST000003191677131351_1360552.3333333333334707.0RepeatNote=55%3B approximate
TgeneTROchrX:54839457chrX:54953016ENST000003191677131361_1370552.3333333333334707.0RepeatNote=56%3B approximate
TgeneTROchrX:54839457chrX:54953016ENST000003191677131371_1380552.3333333333334707.0RepeatNote=57%3B approximate
TgeneTROchrX:54839457chrX:54953016ENST000003191677131381_1390552.3333333333334707.0RepeatNote=58%3B approximate
TgeneTROchrX:54839457chrX:54953016ENST000003191677131391_1400552.3333333333334707.0RepeatNote=59%3B approximate
TgeneTROchrX:54839457chrX:54953016ENST000003191677131401_1410552.3333333333334707.0RepeatNote=60%3B approximate
TgeneTROchrX:54839457chrX:54953016ENST000003191677131411_1420552.3333333333334707.0RepeatNote=61%3B approximate
TgeneTROchrX:54839457chrX:54953016ENST000003191677131421_1430552.3333333333334707.0RepeatNote=62%3B approximate
TgeneTROchrX:54839457chrX:54953016ENST00000319167713751_760552.3333333333334707.0RepeatNote=1
TgeneTROchrX:54839457chrX:54953016ENST00000319167713769_778552.3333333333334707.0RepeatNote=2
TgeneTROchrX:54839457chrX:54953016ENST00000319167713779_786552.3333333333334707.0RepeatNote=3%3B approximate
TgeneTROchrX:54839457chrX:54953016ENST00000319167713787_796552.3333333333334707.0RepeatNote=4
TgeneTROchrX:54839457chrX:54953016ENST00000319167713805_814552.3333333333334707.0RepeatNote=5
TgeneTROchrX:54839457chrX:54953016ENST00000319167713823_833552.3333333333334707.0RepeatNote=6%3B approximate
TgeneTROchrX:54839457chrX:54953016ENST00000319167713841_850552.3333333333334707.0RepeatNote=7
TgeneTROchrX:54839457chrX:54953016ENST00000319167713859_870552.3333333333334707.0RepeatNote=8%3B approximate
TgeneTROchrX:54839457chrX:54953016ENST00000319167713879_890552.3333333333334707.0RepeatNote=9%3B approximate
TgeneTROchrX:54839457chrX:54953016ENST00000319167713901_910552.3333333333334707.0RepeatNote=10
TgeneTROchrX:54839457chrX:54953016ENST00000319167713911_920552.3333333333334707.0RepeatNote=11
TgeneTROchrX:54839457chrX:54953016ENST00000319167713921_930552.3333333333334707.0RepeatNote=12
TgeneTROchrX:54839457chrX:54953016ENST00000319167713931_940552.3333333333334707.0RepeatNote=13
TgeneTROchrX:54839457chrX:54953016ENST00000319167713941_950552.3333333333334707.0RepeatNote=14
TgeneTROchrX:54839457chrX:54953016ENST00000319167713951_960552.3333333333334707.0RepeatNote=15%3B approximate
TgeneTROchrX:54839457chrX:54953016ENST00000319167713961_970552.3333333333334707.0RepeatNote=16
TgeneTROchrX:54839457chrX:54953016ENST00000319167713971_980552.3333333333334707.0RepeatNote=17
TgeneTROchrX:54839457chrX:54953016ENST00000319167713981_990552.3333333333334707.0RepeatNote=18
TgeneTROchrX:54839457chrX:54953016ENST00000319167713991_1000552.3333333333334707.0RepeatNote=19
TgeneTROchrX:54839457chrX:54953016ENST000003750227131001_1010552.3333333333334707.0RepeatNote=20
TgeneTROchrX:54839457chrX:54953016ENST000003750227131011_1020552.3333333333334707.0RepeatNote=21
TgeneTROchrX:54839457chrX:54953016ENST000003750227131021_1030552.3333333333334707.0RepeatNote=22%3B approximate
TgeneTROchrX:54839457chrX:54953016ENST000003750227131031_1040552.3333333333334707.0RepeatNote=23
TgeneTROchrX:54839457chrX:54953016ENST000003750227131041_1050552.3333333333334707.0RepeatNote=24
TgeneTROchrX:54839457chrX:54953016ENST000003750227131051_1060552.3333333333334707.0RepeatNote=25
TgeneTROchrX:54839457chrX:54953016ENST000003750227131061_1070552.3333333333334707.0RepeatNote=26
TgeneTROchrX:54839457chrX:54953016ENST000003750227131071_1080552.3333333333334707.0RepeatNote=27%3B approximate
TgeneTROchrX:54839457chrX:54953016ENST000003750227131081_1090552.3333333333334707.0RepeatNote=28%3B approximate
TgeneTROchrX:54839457chrX:54953016ENST000003750227131091_1100552.3333333333334707.0RepeatNote=29
TgeneTROchrX:54839457chrX:54953016ENST000003750227131101_1110552.3333333333334707.0RepeatNote=30
TgeneTROchrX:54839457chrX:54953016ENST000003750227131111_1120552.3333333333334707.0RepeatNote=31
TgeneTROchrX:54839457chrX:54953016ENST000003750227131121_1130552.3333333333334707.0RepeatNote=32
TgeneTROchrX:54839457chrX:54953016ENST000003750227131131_1140552.3333333333334707.0RepeatNote=33
TgeneTROchrX:54839457chrX:54953016ENST000003750227131141_1150552.3333333333334707.0RepeatNote=34
TgeneTROchrX:54839457chrX:54953016ENST000003750227131151_1160552.3333333333334707.0RepeatNote=35
TgeneTROchrX:54839457chrX:54953016ENST000003750227131161_1170552.3333333333334707.0RepeatNote=36
TgeneTROchrX:54839457chrX:54953016ENST000003750227131171_1180552.3333333333334707.0RepeatNote=37%3B approximate
TgeneTROchrX:54839457chrX:54953016ENST000003750227131181_1190552.3333333333334707.0RepeatNote=38%3B approximate
TgeneTROchrX:54839457chrX:54953016ENST000003750227131191_1200552.3333333333334707.0RepeatNote=39
TgeneTROchrX:54839457chrX:54953016ENST000003750227131201_1210552.3333333333334707.0RepeatNote=40
TgeneTROchrX:54839457chrX:54953016ENST000003750227131211_1220552.3333333333334707.0RepeatNote=41
TgeneTROchrX:54839457chrX:54953016ENST000003750227131221_1230552.3333333333334707.0RepeatNote=42%3B approximate
TgeneTROchrX:54839457chrX:54953016ENST000003750227131231_1240552.3333333333334707.0RepeatNote=43%3B approximate
TgeneTROchrX:54839457chrX:54953016ENST000003750227131241_1250552.3333333333334707.0RepeatNote=44
TgeneTROchrX:54839457chrX:54953016ENST000003750227131251_1260552.3333333333334707.0RepeatNote=45
TgeneTROchrX:54839457chrX:54953016ENST000003750227131261_1270552.3333333333334707.0RepeatNote=46%3B approximate
TgeneTROchrX:54839457chrX:54953016ENST000003750227131271_1280552.3333333333334707.0RepeatNote=47
TgeneTROchrX:54839457chrX:54953016ENST000003750227131281_1290552.3333333333334707.0RepeatNote=48
TgeneTROchrX:54839457chrX:54953016ENST000003750227131291_1300552.3333333333334707.0RepeatNote=49
TgeneTROchrX:54839457chrX:54953016ENST000003750227131301_1310552.3333333333334707.0RepeatNote=50%3B approximate
TgeneTROchrX:54839457chrX:54953016ENST000003750227131311_1320552.3333333333334707.0RepeatNote=51
TgeneTROchrX:54839457chrX:54953016ENST000003750227131321_1330552.3333333333334707.0RepeatNote=52%3B approximate
TgeneTROchrX:54839457chrX:54953016ENST000003750227131331_1340552.3333333333334707.0RepeatNote=53%3B approximate
TgeneTROchrX:54839457chrX:54953016ENST000003750227131341_1350552.3333333333334707.0RepeatNote=54%3B approximate
TgeneTROchrX:54839457chrX:54953016ENST000003750227131351_1360552.3333333333334707.0RepeatNote=55%3B approximate
TgeneTROchrX:54839457chrX:54953016ENST000003750227131361_1370552.3333333333334707.0RepeatNote=56%3B approximate
TgeneTROchrX:54839457chrX:54953016ENST000003750227131371_1380552.3333333333334707.0RepeatNote=57%3B approximate
TgeneTROchrX:54839457chrX:54953016ENST000003750227131381_1390552.3333333333334707.0RepeatNote=58%3B approximate
TgeneTROchrX:54839457chrX:54953016ENST000003750227131391_1400552.3333333333334707.0RepeatNote=59%3B approximate
TgeneTROchrX:54839457chrX:54953016ENST000003750227131401_1410552.3333333333334707.0RepeatNote=60%3B approximate
TgeneTROchrX:54839457chrX:54953016ENST000003750227131411_1420552.3333333333334707.0RepeatNote=61%3B approximate
TgeneTROchrX:54839457chrX:54953016ENST000003750227131421_1430552.3333333333334707.0RepeatNote=62%3B approximate
TgeneTROchrX:54839457chrX:54953016ENST00000375022713751_760552.3333333333334707.0RepeatNote=1
TgeneTROchrX:54839457chrX:54953016ENST00000375022713769_778552.3333333333334707.0RepeatNote=2
TgeneTROchrX:54839457chrX:54953016ENST00000375022713779_786552.3333333333334707.0RepeatNote=3%3B approximate
TgeneTROchrX:54839457chrX:54953016ENST00000375022713787_796552.3333333333334707.0RepeatNote=4
TgeneTROchrX:54839457chrX:54953016ENST00000375022713805_814552.3333333333334707.0RepeatNote=5
TgeneTROchrX:54839457chrX:54953016ENST00000375022713823_833552.3333333333334707.0RepeatNote=6%3B approximate
TgeneTROchrX:54839457chrX:54953016ENST00000375022713841_850552.3333333333334707.0RepeatNote=7
TgeneTROchrX:54839457chrX:54953016ENST00000375022713859_870552.3333333333334707.0RepeatNote=8%3B approximate
TgeneTROchrX:54839457chrX:54953016ENST00000375022713879_890552.3333333333334707.0RepeatNote=9%3B approximate
TgeneTROchrX:54839457chrX:54953016ENST00000375022713901_910552.3333333333334707.0RepeatNote=10
TgeneTROchrX:54839457chrX:54953016ENST00000375022713911_920552.3333333333334707.0RepeatNote=11
TgeneTROchrX:54839457chrX:54953016ENST00000375022713921_930552.3333333333334707.0RepeatNote=12
TgeneTROchrX:54839457chrX:54953016ENST00000375022713931_940552.3333333333334707.0RepeatNote=13
TgeneTROchrX:54839457chrX:54953016ENST00000375022713941_950552.3333333333334707.0RepeatNote=14
TgeneTROchrX:54839457chrX:54953016ENST00000375022713951_960552.3333333333334707.0RepeatNote=15%3B approximate
TgeneTROchrX:54839457chrX:54953016ENST00000375022713961_970552.3333333333334707.0RepeatNote=16
TgeneTROchrX:54839457chrX:54953016ENST00000375022713971_980552.3333333333334707.0RepeatNote=17
TgeneTROchrX:54839457chrX:54953016ENST00000375022713981_990552.3333333333334707.0RepeatNote=18
TgeneTROchrX:54839457chrX:54953016ENST00000375022713991_1000552.3333333333334707.0RepeatNote=19

- Not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneMAGED2chrX:54839457chrX:54953016ENST00000218439+812279_478388.3333333333333607.0DomainMAGE
HgeneMAGED2chrX:54839457chrX:54953016ENST00000375053+812279_478388.3333333333333607.0DomainMAGE
HgeneMAGED2chrX:54839457chrX:54953016ENST00000375058+813279_478388.3333333333333628.3333333333334DomainMAGE
HgeneMAGED2chrX:54839457chrX:54953016ENST00000375068+813279_478388.3333333333333581.3333333333334DomainMAGE
HgeneMAGED2chrX:54839457chrX:54953016ENST00000396224+812279_478388.3333333333333607.0DomainMAGE
TgeneTROchrX:54839457chrX:54953016ENST00000173898713444_642552.33333333333341485.3333333333333DomainMAGE
TgeneTROchrX:54839457chrX:54953016ENST00000319167713444_642552.3333333333334707.0DomainMAGE
TgeneTROchrX:54839457chrX:54953016ENST00000375022713444_642552.3333333333334707.0DomainMAGE


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Fusion Protein Structures

check button PDB and CIF files of the predicted fusion proteins
* Here we show the 3D structure of the fusion proteins using Mol*. AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Model confidence is shown from the pLDDT values per residue. pLDDT corresponds to the model’s prediction of its score on the local Distance Difference Test. It is a measure of local accuracy (from AlphfaFold website). To color code individual residues, we transformed individual PDB files into CIF format.
Fusion protein PDB link (fusion AA seq ID in FusionPDB)HgeneHchrHbpHstrandTgeneTchrTbpTstrandAA seqLen(AA seq)


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pLDDT score distribution

check button pLDDT score distribution of the predicted wild-type structures of two partner proteins from AlphaFold2
* AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100.
MAGED2_pLDDT.png
all structure
all structure
TRO_pLDDT.png
all structure
all structure

check button pLDDT score distribution of the predicted fusion protein structures from AlphaFold2
* AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100.


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Ramachandran Plot of Fusion Protein Structure


check button Ramachandran plot of the torsional angles - phi (φ)and psi (ψ) - of the residues (amino acids) contained in this fusion protein peptide.
Fusion AA seq ID in FusionPDB and their Ramachandran plots

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Fusion Protein-Protein Interaction


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type from validated records (BIOGRID-3.4.160)
GenePPI interactors


check button Protein-protein interactors based on sequence similarity (STRING)
GeneSTRING network
MAGED2
TRO


check button - Retained interactions in fusion protein (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost interactions due to fusion (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs to MAGED2-TRO


check button Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDrugSourcePMID

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Related Diseases to MAGED2-TRO


check button Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDiseaseSourcePMID

check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource