UTHEALTH HOME    ABOUT SBMI    A-Z    WEBMAIL    INSIDE THE UNIVERSITY
FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact

Terms of Use
Center for Computational Systems Medicine level1
leaf

Fusion Gene Summary

leaf

Fusion Gene Sample Information

leaf

Fusion ORF Analysis

leaf

Fusion Amino Acid Sequences

leaf

Fusion Protein Functional Features

leaf

Fusion Protein-Protein Interaction

leaf

Related drugs with this fusion protein

leaf

Related disease with this fusion protein

Fusion Protein:MDM1-ABCC1

Fusion Protein Summary

check button Fusion gene summary
Fusion partner gene informationFusion gene name: MDM1-ABCC1
FusionPDB ID: 52377
FusionGDB2.0 ID: 52377
HgeneTgene
Gene symbol

MDM1

ABCC1

Gene ID

56890

4363

Gene nameMdm1 nuclear proteinATP binding cassette subfamily C member 1
Synonyms-ABC29|ABCC|GS-X|MRP|MRP1
Cytomap

12q15

16p13.11

Type of geneprotein-codingprotein-coding
Descriptionnuclear protein MDM1Mdm4, transformed 3T3 cell double minute 1, p53 binding proteinnuclear protein double minute 1multidrug resistance-associated protein 1ATP-binding cassette transporter variant ABCC1delta-ex13ATP-binding cassette transporter variant ABCC1delta-ex13&14ATP-binding cassette transporter variant ABCC1delta-ex25ATP-binding cassette transporter varian
Modification date2020031320200313
UniProtAcc

Q8TC05

Q96J66

Ensembl transtripts involved in fusion geneENST idsENST00000303145, ENST00000411698, 
ENST00000540418, ENST00000393543, 
ENST00000430606, ENST00000545724, 
ENST00000576557, ENST00000345148, 
ENST00000346370, ENST00000349029, 
ENST00000351154, ENST00000399408, 
ENST00000399410, 
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)* DoF score11 X 10 X 5=55016 X 13 X 5=1040
# samples 1116
** MAII scorelog2(11/550*10)=-2.32192809488736
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(16/1040*10)=-2.70043971814109
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context (manual curation of fusion genes in FusionPDB)

PubMed: MDM1 [Title/Abstract] AND ABCC1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)MDM1(68707223)-ABCC1(16108348), # samples:3
Anticipated loss of major functional domain due to fusion event.MDM1-ABCC1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
MDM1-ABCC1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
MDM1-ABCC1 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
MDM1-ABCC1 seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across MDM1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across ABCC1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure


Top

Fusion Gene Sample Information

check buttonFusion gene information from FusionGDB2.0.
check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-BH-A0B1-01AMDM1chr12

68707223

-ABCC1chr16

16108348

+


Top

Fusion ORF Analysis


check buttonFusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000303145MDM1chr1268707223-ENST00000399410ABCC1chr1616108348+783218068760501987
ENST00000303145MDM1chr1268707223-ENST00000349029ABCC1chr1616108348+749918068757051872
ENST00000303145MDM1chr1268707223-ENST00000351154ABCC1chr1616108348+766718068758731928
ENST00000303145MDM1chr1268707223-ENST00000399408ABCC1chr1616108348+787418068760801997
ENST00000303145MDM1chr1268707223-ENST00000345148ABCC1chr1616108348+764918068758551922
ENST00000303145MDM1chr1268707223-ENST00000346370ABCC1chr1616108348+767618068758821931
ENST00000411698MDM1chr1268707223-ENST00000399410ABCC1chr1616108348+768116554158991952
ENST00000411698MDM1chr1268707223-ENST00000349029ABCC1chr1616108348+734816554155541837
ENST00000411698MDM1chr1268707223-ENST00000351154ABCC1chr1616108348+751616554157221893
ENST00000411698MDM1chr1268707223-ENST00000399408ABCC1chr1616108348+772316554159291962
ENST00000411698MDM1chr1268707223-ENST00000345148ABCC1chr1616108348+749816554157041887
ENST00000411698MDM1chr1268707223-ENST00000346370ABCC1chr1616108348+752516554157311896

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000303145ENST00000399410MDM1chr1268707223-ABCC1chr1616108348+0.0006715620.9993285
ENST00000303145ENST00000349029MDM1chr1268707223-ABCC1chr1616108348+0.0009445460.99905545
ENST00000303145ENST00000351154MDM1chr1268707223-ABCC1chr1616108348+0.0009909970.999009
ENST00000303145ENST00000399408MDM1chr1268707223-ABCC1chr1616108348+0.0004426650.9995573
ENST00000303145ENST00000345148MDM1chr1268707223-ABCC1chr1616108348+0.000718070.99928194
ENST00000303145ENST00000346370MDM1chr1268707223-ABCC1chr1616108348+0.0008836050.99911636
ENST00000411698ENST00000399410MDM1chr1268707223-ABCC1chr1616108348+0.0006074990.9993925
ENST00000411698ENST00000349029MDM1chr1268707223-ABCC1chr1616108348+0.0008563030.9991437
ENST00000411698ENST00000351154MDM1chr1268707223-ABCC1chr1616108348+0.0009017650.9990983
ENST00000411698ENST00000399408MDM1chr1268707223-ABCC1chr1616108348+0.0003995920.99960047
ENST00000411698ENST00000345148MDM1chr1268707223-ABCC1chr1616108348+0.0006495590.9993505
ENST00000411698ENST00000346370MDM1chr1268707223-ABCC1chr1616108348+0.0007995490.9992005

Top

Fusion Amino Acid Sequences


check button For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

>52377_52377_1_MDM1-ABCC1_MDM1_chr12_68707223_ENST00000303145_ABCC1_chr16_16108348_ENST00000345148_length(amino acids)=1922AA_BP=573
MPVRFKGLSEYQRNFLWKKSYLSESCNSSVGRKYPWAGLRSDQLGITKEPSFISKRRVPYHDPQISKSLEWNGAISESNVVASPEPEAPE
TPKSQEAEQKDVTQERVHSLEASRVPKRTRSHSADSRAEGASDVENNEGVTNHTPVNENVELEHSTKVLSENVDNGLDRLLRKKAGLTVV
PSYNALRNSEYQRQFVWKTSKETAPAFAANQVFHNKSQFVPPFKGNSVIHETEYKRNFKGLSPVKEPKLRNDLRENRNLETVSPERKSNK
IDDRLKLEAEMELKDLHQPKRKLTPWKHQRLGKVNSEYRAKFLSPAQYLYKAGAWTHVKGNMPNQVKELREKAEFYRKRVQGTHFSRDHL
NQILSDSNCCWDVSSTTSSEGTVSSNIRALDLAGDPTSHKTLQKCPSTEPEEKGNIVEEQPQKNTTEKLGVSAPTIPVRRRLAWDTENTS
EDVQKQPGEKEEEDDNEEEGDRKTGKQAFMGEQEKLDVREKSKADKMKEGSDSSVSSEKGGRLPTPKLRELGGIQRTHHDLTTPAVGGAV
LVSPSKMKPPAPEQRKRMTSQDCLETSKNDFTKLLATFLIQLERRKGVQSSGIMLTFWLVALVCALAILRSKIMTALKEDAQVDLFRDIT
FYVYFSLLLIQLVLSCFSDRSPLFSETIHDPNPCPESSASFLSRITFWWITGLIVRGYRQPLEGSDLWSLNKEDTSEQVVPVLVKNWKKE
CAKTRKQPVKVVYSSKDPAQPKESSKVDANEEVEALIVKSPQKEWNPSLFKVLYKTFGPYFLMSFFFKAIHDLMMFSGPQILKLLIKFVN
DTKAPDWQGYFYTVLLFVTACLQTLVLHQYFHICFVSGMRIKTAVIGAVYRKALVITNSARKSSTVGEIVNLMSVDAQRFMDLATYINMI
WSAPLQVILALYLLWLNLGPSVLAGVAVMVLMVPVNAVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFKDKVLAIRQE
ELKVLKKSAYLSAVGTFTWVCTPFLVALCTFAVYVTIDENNILDAQTAFVSLALFNILRFPLNILPMVISSIVQASVSLKRLRIFLSHEE
LEPDSIERRPVKDGGGTNSITVRNATFTWARSDPPTLNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVAIKGSVAYVPQQ
AWIQNDSLRENILFGCQLEEPYYRSVIQACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYSNADIYLFDDPLSAVDAHVGK
HIFENVIGPKGMLKNKTRILVTHSMSYLPQVDVIIVMSGGKISEMGSYQELLARDGAFAEFLRTYASTEQEQDAEENGVTGVSGPGKEAK
QMENGMLVTDSAGKQLQRQLSSSSSYSGDISRHHNSTAELQKAEAKKEETWKLMEADKAQTGQVKLSVYWDYMKAIGLFISFLSIFLFMC
NHVSALASNYWLSLWTDDPIVNGTQEHTKVRLSVYGALGISQGIAVFGYSMAVSIGGILASRCLHVDLLHSILRSPMSFFERTPSGNLVN
RFSKELDTVDSMIPEVIKMFMGSLFNVIGACIVILLATPIAAIIIPPLGLIYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSV
IRAFEEQERFIHQSDLKVDENQKAYYPSIVANRWLAVRLECVGNCIVLFAALFAVISRHSLSAGLVGLSVSYSLQVTTYLNWLVRMSSEM
ETNIVAVERLKEYSETEKEAPWQIQETAPPSSWPQVGRVEFRNYCLRYREDLDFVLRHINVTINGGEKVGIVGRTGAGKSSLTLGLFRIN
ESAEGEIIIDGINIAKIGLHDLRFKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWTSLELAHLKDFVSALPDKLDHECAEGGENLRVIV

--------------------------------------------------------------

>52377_52377_2_MDM1-ABCC1_MDM1_chr12_68707223_ENST00000303145_ABCC1_chr16_16108348_ENST00000346370_length(amino acids)=1931AA_BP=573
MPVRFKGLSEYQRNFLWKKSYLSESCNSSVGRKYPWAGLRSDQLGITKEPSFISKRRVPYHDPQISKSLEWNGAISESNVVASPEPEAPE
TPKSQEAEQKDVTQERVHSLEASRVPKRTRSHSADSRAEGASDVENNEGVTNHTPVNENVELEHSTKVLSENVDNGLDRLLRKKAGLTVV
PSYNALRNSEYQRQFVWKTSKETAPAFAANQVFHNKSQFVPPFKGNSVIHETEYKRNFKGLSPVKEPKLRNDLRENRNLETVSPERKSNK
IDDRLKLEAEMELKDLHQPKRKLTPWKHQRLGKVNSEYRAKFLSPAQYLYKAGAWTHVKGNMPNQVKELREKAEFYRKRVQGTHFSRDHL
NQILSDSNCCWDVSSTTSSEGTVSSNIRALDLAGDPTSHKTLQKCPSTEPEEKGNIVEEQPQKNTTEKLGVSAPTIPVRRRLAWDTENTS
EDVQKQPGEKEEEDDNEEEGDRKTGKQAFMGEQEKLDVREKSKADKMKEGSDSSVSSEKGGRLPTPKLRELGGIQRTHHDLTTPAVGGAV
LVSPSKMKPPAPEQRKRMTSQDCLETSKNDFTKLLATFLIQLERRKGVQSSGIMLTFWLVALVCALAILRSKIMTALKEDAQVDLFRDIT
FYVYFSLLLIQLVLSCFSDRSPLFSETIHDPNPCPESSASFLSRITFWWITGLIVRGYRQPLEGSDLWSLNKEDTSEQVVPVLVKNWKKE
CAKTRKQPVKVVYSSKDPAQPKESSKVDANEEVEALIVKSPQKEWNPSLFKVLYKTFGPYFLMSFFFKAIHDLMMFSGPQILKLLIKFVN
DTKAPDWQGYFYTVLLFVTACLQTLVLHQYFHICFVSGMRIKTAVIGAVYRKALVITNSARKSSTVGEIVNLMSVDAQRFMDLATYINMI
WSAPLQVILALYLLWLNLGPSVLAGVAVMVLMVPVNAVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFKDKVLAIRQE
ELKVLKKSAYLSAVGTFTWVCTPFLVALCTFAVYVTIDENNILDAQTAFVSLALFNILRFPLNILPMVISSIVQASVSLKRLRIFLSHEE
LEPDSIERRPVKDGGGTNSITVRNATFTWARSDPPTLNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVAIKGSVAYVPQQ
AWIQNDSLRENILFGCQLEEPYYRSVIQACALLPDLEILPSGDRTEIGEKTRILVTHSMSYLPQVDVIIVMSGGKISEMGSYQELLARDG
AFAEFLRTYASTEQEQDAEENGVTGVSGPGKEAKQMENGMLVTDSAGKQLQRQLSSSSSYSGDISRHHNSTAELQKAEAKKEETWKLMEA
DKAQTGQVKLSVYWDYMKAIGLFISFLSIFLFMCNHVSALASNYWLSLWTDDPIVNGTQEHTKVRLSVYGALGISQGIAVFGYSMAVSIG
GILASRCLHVDLLHSILRSPMSFFERTPSGNLVNRFSKELDTVDSMIPEVIKMFMGSLFNVIGACIVILLATPIAAIIIPPLGLIYFFVQ
RFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIHQSDLKVDENQKAYYPSIVANRWLAVRLECVGNCIVLFAALFAVI
SRHSLSAGLVGLSVSYSLQVTTYLNWLVRMSSEMETNIVAVERLKEYSETEKEAPWQIQETAPPSSWPQVGRVEFRNYCLRYREDLDFVL
RHINVTINGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGINIAKIGLHDLRFKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVW
TSLELAHLKDFVSALPDKLDHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDDLIQSTIRTQFEDCTVLTIAHRLNT

--------------------------------------------------------------

>52377_52377_3_MDM1-ABCC1_MDM1_chr12_68707223_ENST00000303145_ABCC1_chr16_16108348_ENST00000349029_length(amino acids)=1872AA_BP=573
MPVRFKGLSEYQRNFLWKKSYLSESCNSSVGRKYPWAGLRSDQLGITKEPSFISKRRVPYHDPQISKSLEWNGAISESNVVASPEPEAPE
TPKSQEAEQKDVTQERVHSLEASRVPKRTRSHSADSRAEGASDVENNEGVTNHTPVNENVELEHSTKVLSENVDNGLDRLLRKKAGLTVV
PSYNALRNSEYQRQFVWKTSKETAPAFAANQVFHNKSQFVPPFKGNSVIHETEYKRNFKGLSPVKEPKLRNDLRENRNLETVSPERKSNK
IDDRLKLEAEMELKDLHQPKRKLTPWKHQRLGKVNSEYRAKFLSPAQYLYKAGAWTHVKGNMPNQVKELREKAEFYRKRVQGTHFSRDHL
NQILSDSNCCWDVSSTTSSEGTVSSNIRALDLAGDPTSHKTLQKCPSTEPEEKGNIVEEQPQKNTTEKLGVSAPTIPVRRRLAWDTENTS
EDVQKQPGEKEEEDDNEEEGDRKTGKQAFMGEQEKLDVREKSKADKMKEGSDSSVSSEKGGRLPTPKLRELGGIQRTHHDLTTPAVGGAV
LVSPSKMKPPAPEQRKRMTSQDCLETSKNDFTKLLATFLIQLERRKGVQSSGIMLTFWLVALVCALAILRSKIMTALKEDAQVDLFRDIT
FYVYFSLLLIQLVLSCFSDRSPLFSETIHDPNPCPESSASFLSRITFWWITGLIVRGYRQPLEGSDLWSLNKEDTSEQVVPVLVKNWKKE
CAKTRKQPVKVVYSSKDPAQPKESSKVDANEEVEALIVKSPQKEWNPSLFKVLYKTFGPYFLMSFFFKAIHDLMMFSGPQILKLLIKFVN
DTKAPDWQGYFYTVLLFVTACLQTLVLHQYFHICFVSGMRIKTAVIGAVYRKALVITNSARKSSTVGEIVNLMSVDAQRFMDLATYINMI
WSAPLQVILALYLLWLNLGPSVLAGVAVMVLMVPVNAVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFKDKVLAIRQE
ELKVLKKSAYLSAVGTFTWVCTPFLVALCTFAVYVTIDENNILDAQTAFVSLALFNILRFPLNILPMVISSIVQASVSLKRLRIFLSHEE
LEPDSIERRPVKDGGGTNSITVRNATFTWARSDPPTLNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVAIKTRILVTHSM
SYLPQVDVIIVMSGGKISEMGSYQELLARDGAFAEFLRTYASTEQEQDAEENGVTGVSGPGKEAKQMENGMLVTDSAGKQLQRQLSSSSS
YSGDISRHHNSTAELQKAEAKKEETWKLMEADKAQTGQVKLSVYWDYMKAIGLFISFLSIFLFMCNHVSALASNYWLSLWTDDPIVNGTQ
EHTKVRLSVYGALGISQGIAVFGYSMAVSIGGILASRCLHVDLLHSILRSPMSFFERTPSGNLVNRFSKELDTVDSMIPEVIKMFMGSLF
NVIGACIVILLATPIAAIIIPPLGLIYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIHQSDLKVDENQKAY
YPSIVANRWLAVRLECVGNCIVLFAALFAVISRHSLSAGLVGLSVSYSLQVTTYLNWLVRMSSEMETNIVAVERLKEYSETEKEAPWQIQ
ETAPPSSWPQVGRVEFRNYCLRYREDLDFVLRHINVTINGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGINIAKIGLHDLRFK
ITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWTSLELAHLKDFVSALPDKLDHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAA

--------------------------------------------------------------

>52377_52377_4_MDM1-ABCC1_MDM1_chr12_68707223_ENST00000303145_ABCC1_chr16_16108348_ENST00000351154_length(amino acids)=1928AA_BP=573
MPVRFKGLSEYQRNFLWKKSYLSESCNSSVGRKYPWAGLRSDQLGITKEPSFISKRRVPYHDPQISKSLEWNGAISESNVVASPEPEAPE
TPKSQEAEQKDVTQERVHSLEASRVPKRTRSHSADSRAEGASDVENNEGVTNHTPVNENVELEHSTKVLSENVDNGLDRLLRKKAGLTVV
PSYNALRNSEYQRQFVWKTSKETAPAFAANQVFHNKSQFVPPFKGNSVIHETEYKRNFKGLSPVKEPKLRNDLRENRNLETVSPERKSNK
IDDRLKLEAEMELKDLHQPKRKLTPWKHQRLGKVNSEYRAKFLSPAQYLYKAGAWTHVKGNMPNQVKELREKAEFYRKRVQGTHFSRDHL
NQILSDSNCCWDVSSTTSSEGTVSSNIRALDLAGDPTSHKTLQKCPSTEPEEKGNIVEEQPQKNTTEKLGVSAPTIPVRRRLAWDTENTS
EDVQKQPGEKEEEDDNEEEGDRKTGKQAFMGEQEKLDVREKSKADKMKEGSDSSVSSEKGGRLPTPKLRELGGIQRTHHDLTTPAVGGAV
LVSPSKMKPPAPEQRKRMTSQDCLETSKNDFTKLLATFLIQLERRKGVQSSGIMLTFWLVALVCALAILRSKIMTALKEDAQVDLFRDIT
FYVYFSLLLIQLVLSCFSDRSPLFSETIHDPNPCPESSASFLSRITFWWITGLIVRGYRQPLEGSDLWSLNKEDTSEQVVPVLVKNWKKE
CAKTRKQPVKVVYSSKDPAQPKESSKVDANEEVEALIVKSPQKEWNPSLFKVLYKTFGPYFLMSFFFKAIHDLMMFSGPQILKLLIKFVN
DTKAPDWQGYFYTVLLFVTACLQTLVLHQYFHICFVSGMRIKTAVIGAVYRKALVITNSARKSSTVGEIVNLMSVDAQRFMDLATYINMI
WSAPLQVILALYLLWLNLGPSVLAGVAVMVLMVPVNAVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFKDKVLAIRQE
ELKVLKKSAYLSAVGTFTWVCTPFLVALCTFAVYVTIDENNILDAQTAFVSLALFNILRFPLNILPMVISSIVQASVSLKRLRIFLSHEE
LEPDSIERRPVKDGGGTNSITVRNATFTWARSDPPTLNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVAIKGVNLSGGQK
QRVSLARAVYSNADIYLFDDPLSAVDAHVGKHIFENVIGPKGMLKNKTRILVTHSMSYLPQVDVIIVMSGGKISEMGSYQELLARDGAFA
EFLRTYASTEQEQDAEENGVTGVSGPGKEAKQMENGMLVTDSAGKQLQRQLSSSSSYSGDISRHHNSTAELQKAEAKKEETWKLMEADKA
QTGQVKLSVYWDYMKAIGLFISFLSIFLFMCNHVSALASNYWLSLWTDDPIVNGTQEHTKVRLSVYGALGISQGIAVFGYSMAVSIGGIL
ASRCLHVDLLHSILRSPMSFFERTPSGNLVNRFSKELDTVDSMIPEVIKMFMGSLFNVIGACIVILLATPIAAIIIPPLGLIYFFVQRFY
VASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIHQSDLKVDENQKAYYPSIVANRWLAVRLECVGNCIVLFAALFAVISRH
SLSAGLVGLSVSYSLQVTTYLNWLVRMSSEMETNIVAVERLKEYSETEKEAPWQIQETAPPSSWPQVGRVEFRNYCLRYREDLDFVLRHI
NVTINGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGINIAKIGLHDLRFKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWTSL
ELAHLKDFVSALPDKLDHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDDLIQSTIRTQFEDCTVLTIAHRLNTIMD

--------------------------------------------------------------

>52377_52377_5_MDM1-ABCC1_MDM1_chr12_68707223_ENST00000303145_ABCC1_chr16_16108348_ENST00000399408_length(amino acids)=1997AA_BP=573
MPVRFKGLSEYQRNFLWKKSYLSESCNSSVGRKYPWAGLRSDQLGITKEPSFISKRRVPYHDPQISKSLEWNGAISESNVVASPEPEAPE
TPKSQEAEQKDVTQERVHSLEASRVPKRTRSHSADSRAEGASDVENNEGVTNHTPVNENVELEHSTKVLSENVDNGLDRLLRKKAGLTVV
PSYNALRNSEYQRQFVWKTSKETAPAFAANQVFHNKSQFVPPFKGNSVIHETEYKRNFKGLSPVKEPKLRNDLRENRNLETVSPERKSNK
IDDRLKLEAEMELKDLHQPKRKLTPWKHQRLGKVNSEYRAKFLSPAQYLYKAGAWTHVKGNMPNQVKELREKAEFYRKRVQGTHFSRDHL
NQILSDSNCCWDVSSTTSSEGTVSSNIRALDLAGDPTSHKTLQKCPSTEPEEKGNIVEEQPQKNTTEKLGVSAPTIPVRRRLAWDTENTS
EDVQKQPGEKEEEDDNEEEGDRKTGKQAFMGEQEKLDVREKSKADKMKEGSDSSVSSEKGGRLPTPKLRELGGIQRTHHDLTTPAVGGAV
LVSPSKMKPPAPEQRKRMTSQDCLETSKNDFTKLLATFLIQLERRKGVQSSGIMLTFWLVALVCALAILRSKIMTALKEDAQVDLFRDIT
FYVYFSLLLIQLVLSCFSDRSPLFSETIHDPNPCPESSASFLSRITFWWITGLIVRGYRQPLEGSDLWSLNKEDTSEQVVPVLVKNWKKE
CAKTRKQPVKVVYSSKDPAQPKESSKVDANEEVEALIVKSPQKEWNPSLFKVLYKTFGPYFLMSFFFKAIHDLMMFSGPQILKLLIKFVN
DTKAPDWQGYFYTVLLFVTACLQTLVLHQYFHICFVSGMRIKTAVIGAVYRKALVITNSARKSSTVGEIVNLMSVDAQRFMDLATYINMI
WSAPLQVILALYLLWLNLGPSVLAGVAVMVLMVPVNAVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFKDKVLAIRQE
ELKVLKKSAYLSAVGTFTWVCTPFLVALCTFAVYVTIDENNILDAQTAFVSLALFNILRFPLNILPMVISSIVQASVSLKRLRIFLSHEE
LEPDSIERRPVKDGGGTNSITVRNATFTWARSDPPTLNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVAIKGSVAYVPQQ
AWIQNDSLRENILFGCQLEEPYYRSVIQACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYSNADIYLFDDPLSAVDAHVGK
HIFENVIGPKGMLKNKTRILVTHSMSYLPQVDVIIVMSGGKISEMGSYQELLARDGAFAEFLRTYASTEQEQDAEENGSTVMDEEEAGVT
GVSGPGKEAKQMENGMLVTDSAGKQLQRQLSSSSSYSGDISRHHNSTAELQKAEAKKEETWKLMEADKAQTGQVKLSVYWDYMKAIGLFI
SFLSIFLFMCNHVSALASNYWLSLWTDDPIVNGTQEHTKVRLSVYGALGISQGIAVFGYSMAVSIGGILASRCLHVDLLHSILRSPMSFF
ERTPSGNLVNRFSKELDTVDSMIPEVIKMFMGSLFNVIGACIVILLATPIAAIIIPPLGLIYFFVQRFYVASSRQLKRLESVSRSPVYSH
FNETLLGVSVIRAFEEQERFIHQSDLKVDENQKAYYPSIVANRWLAVRLECVGNCIVLFAALFAVISRHSLSAGLVGLSVSYSLQVTTYL
NWLVRMSSEMETNIVAVERLKEYSETEKEAPWQIQETAPPSSWPQVGRVEFRNYCLRYREDLDFVLRHINVTINGGEKVGIVGRTGAGKS
SLTLGLFRINESAEGEIIIDGINIAKIGLHDLRFKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWTSLELAHLKDFVSALPDKLDHECA
EGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDDLIQSTIRTQFEDCTVLTIAHRLNTIMDYTRVIVLDKGEIQEYGAPSDL

--------------------------------------------------------------

>52377_52377_6_MDM1-ABCC1_MDM1_chr12_68707223_ENST00000303145_ABCC1_chr16_16108348_ENST00000399410_length(amino acids)=1987AA_BP=573
MPVRFKGLSEYQRNFLWKKSYLSESCNSSVGRKYPWAGLRSDQLGITKEPSFISKRRVPYHDPQISKSLEWNGAISESNVVASPEPEAPE
TPKSQEAEQKDVTQERVHSLEASRVPKRTRSHSADSRAEGASDVENNEGVTNHTPVNENVELEHSTKVLSENVDNGLDRLLRKKAGLTVV
PSYNALRNSEYQRQFVWKTSKETAPAFAANQVFHNKSQFVPPFKGNSVIHETEYKRNFKGLSPVKEPKLRNDLRENRNLETVSPERKSNK
IDDRLKLEAEMELKDLHQPKRKLTPWKHQRLGKVNSEYRAKFLSPAQYLYKAGAWTHVKGNMPNQVKELREKAEFYRKRVQGTHFSRDHL
NQILSDSNCCWDVSSTTSSEGTVSSNIRALDLAGDPTSHKTLQKCPSTEPEEKGNIVEEQPQKNTTEKLGVSAPTIPVRRRLAWDTENTS
EDVQKQPGEKEEEDDNEEEGDRKTGKQAFMGEQEKLDVREKSKADKMKEGSDSSVSSEKGGRLPTPKLRELGGIQRTHHDLTTPAVGGAV
LVSPSKMKPPAPEQRKRMTSQDCLETSKNDFTKLLATFLIQLERRKGVQSSGIMLTFWLVALVCALAILRSKIMTALKEDAQVDLFRDIT
FYVYFSLLLIQLVLSCFSDRSPLFSETIHDPNPCPESSASFLSRITFWWITGLIVRGYRQPLEGSDLWSLNKEDTSEQVVPVLVKNWKKE
CAKTRKQPVKVVYSSKDPAQPKESSKVDANEEVEALIVKSPQKEWNPSLFKVLYKTFGPYFLMSFFFKAIHDLMMFSGPQILKLLIKFVN
DTKAPDWQGYFYTVLLFVTACLQTLVLHQYFHICFVSGMRIKTAVIGAVYRKALVITNSARKSSTVGEIVNLMSVDAQRFMDLATYINMI
WSAPLQVILALYLLWLNLGPSVLAGVAVMVLMVPVNAVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFKDKVLAIRQE
ELKVLKKSAYLSAVGTFTWVCTPFLVALCTFAVYVTIDENNILDAQTAFVSLALFNILRFPLNILPMVISSIVQASVSLKRLRIFLSHEE
LEPDSIERRPVKDGGGTNSITVRNATFTWARSDPPTLNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVAIKGSVAYVPQQ
AWIQNDSLRENILFGCQLEEPYYRSVIQACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYSNADIYLFDDPLSAVDAHVGK
HIFENVIGPKGMLKNKTRILVTHSMSYLPQVDVIIVMSGGKISEMGSYQELLARDGAFAEFLRTYASTEQEQDAEENGVTGVSGPGKEAK
QMENGMLVTDSAGKQLQRQLSSSSSYSGDISRHHNSTAELQKAEAKKEETWKLMEADKAQTGQVKLSVYWDYMKAIGLFISFLSIFLFMC
NHVSALASNYWLSLWTDDPIVNGTQEHTKVRLSVYGALGISQGIAVFGYSMAVSIGGILASRCLHVDLLHSILRSPMSFFERTPSGNLVN
RFSKELDTVDSMIPEVIKMFMGSLFNVIGACIVILLATPIAAIIIPPLGLIYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSV
IRAFEEQERFIHQSDLKVDENQKAYYPSIVANRWLAVRLECVGNCIVLFAALFAVISRHSLSAGLVGLSVSYSLQVTTYLNWLVRMSSEM
ETNIVAVERLKEYSETEKEAPWQIQETAPPSSWPQVGRVEFRNYCLRYREDLDFVLRHINVTINGGEKVGIVGRTGAGKSSLTLGLFRIN
ESAEGEIIIDGINIAKIGLHDLRFKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWTSLELAHLKDFVSALPDKLDHECAEGGENLSVGQ
RQLVCLARALLRKTKILVLDEATAAVDLETDDLIQSTIRTQFEDCTVLTIAHRLNTIMDYTRVIVLDKGEIQEYGAPSDLLQQRGLFYSM

--------------------------------------------------------------

>52377_52377_7_MDM1-ABCC1_MDM1_chr12_68707223_ENST00000411698_ABCC1_chr16_16108348_ENST00000345148_length(amino acids)=1887AA_BP=538
MPVRFKGLSEYQRNFLWKKSYLSESCNSSVGRKYPWAGLRSDQLGITKEPSFISKRRVPYHDPQISKSLEWNGAISESNVVASPEPEAPE
TPKSQEAEQKDVTQERVHSLEASRVPKRTRSHSADSRAEGASDVENNEGVTNHTPVNENVELEHSTKVLSENVDNGVFHNKSQFVPPFKG
NSVIHETEYKRNFKGLSPVKEPKLRNDLRENRNLETVSPERKSNKIDDRLKLEAEMELKDLHQPKRKLTPWKHQRLGKVNSEYRAKFLSP
AQYLYKAGAWTHVKGNMPNQGSLNAMWYAEVKELREKAEFYRKRVQGTHFSRDHLNQILSDSNCCWDVSSTTSSEGTVSSNIRALDLAGD
PTSHKTLQKCPSTEPEEKGNIVEEQPQKNTTEKLGVSAPTIPVRRRLAWDTENTSEDVQKQPGEKEEEDDNEEEGDRKTGKQAFMGEQEK
LDVREKSKADKMKEGSDSSVSSEKGGRLPTPKLRELGGIQRTHHDLTTPAVGGAVLVSPSKMKPPAPEQRKRMTSQDCLETSKNDFTKLL
ATFLIQLERRKGVQSSGIMLTFWLVALVCALAILRSKIMTALKEDAQVDLFRDITFYVYFSLLLIQLVLSCFSDRSPLFSETIHDPNPCP
ESSASFLSRITFWWITGLIVRGYRQPLEGSDLWSLNKEDTSEQVVPVLVKNWKKECAKTRKQPVKVVYSSKDPAQPKESSKVDANEEVEA
LIVKSPQKEWNPSLFKVLYKTFGPYFLMSFFFKAIHDLMMFSGPQILKLLIKFVNDTKAPDWQGYFYTVLLFVTACLQTLVLHQYFHICF
VSGMRIKTAVIGAVYRKALVITNSARKSSTVGEIVNLMSVDAQRFMDLATYINMIWSAPLQVILALYLLWLNLGPSVLAGVAVMVLMVPV
NAVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFKDKVLAIRQEELKVLKKSAYLSAVGTFTWVCTPFLVALCTFAVYV
TIDENNILDAQTAFVSLALFNILRFPLNILPMVISSIVQASVSLKRLRIFLSHEELEPDSIERRPVKDGGGTNSITVRNATFTWARSDPP
TLNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVAIKGSVAYVPQQAWIQNDSLRENILFGCQLEEPYYRSVIQACALLPD
LEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYSNADIYLFDDPLSAVDAHVGKHIFENVIGPKGMLKNKTRILVTHSMSYLPQVDVII
VMSGGKISEMGSYQELLARDGAFAEFLRTYASTEQEQDAEENGVTGVSGPGKEAKQMENGMLVTDSAGKQLQRQLSSSSSYSGDISRHHN
STAELQKAEAKKEETWKLMEADKAQTGQVKLSVYWDYMKAIGLFISFLSIFLFMCNHVSALASNYWLSLWTDDPIVNGTQEHTKVRLSVY
GALGISQGIAVFGYSMAVSIGGILASRCLHVDLLHSILRSPMSFFERTPSGNLVNRFSKELDTVDSMIPEVIKMFMGSLFNVIGACIVIL
LATPIAAIIIPPLGLIYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIHQSDLKVDENQKAYYPSIVANRWL
AVRLECVGNCIVLFAALFAVISRHSLSAGLVGLSVSYSLQVTTYLNWLVRMSSEMETNIVAVERLKEYSETEKEAPWQIQETAPPSSWPQ
VGRVEFRNYCLRYREDLDFVLRHINVTINGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGINIAKIGLHDLRFKITIIPQDPVL

--------------------------------------------------------------

>52377_52377_8_MDM1-ABCC1_MDM1_chr12_68707223_ENST00000411698_ABCC1_chr16_16108348_ENST00000346370_length(amino acids)=1896AA_BP=538
MPVRFKGLSEYQRNFLWKKSYLSESCNSSVGRKYPWAGLRSDQLGITKEPSFISKRRVPYHDPQISKSLEWNGAISESNVVASPEPEAPE
TPKSQEAEQKDVTQERVHSLEASRVPKRTRSHSADSRAEGASDVENNEGVTNHTPVNENVELEHSTKVLSENVDNGVFHNKSQFVPPFKG
NSVIHETEYKRNFKGLSPVKEPKLRNDLRENRNLETVSPERKSNKIDDRLKLEAEMELKDLHQPKRKLTPWKHQRLGKVNSEYRAKFLSP
AQYLYKAGAWTHVKGNMPNQGSLNAMWYAEVKELREKAEFYRKRVQGTHFSRDHLNQILSDSNCCWDVSSTTSSEGTVSSNIRALDLAGD
PTSHKTLQKCPSTEPEEKGNIVEEQPQKNTTEKLGVSAPTIPVRRRLAWDTENTSEDVQKQPGEKEEEDDNEEEGDRKTGKQAFMGEQEK
LDVREKSKADKMKEGSDSSVSSEKGGRLPTPKLRELGGIQRTHHDLTTPAVGGAVLVSPSKMKPPAPEQRKRMTSQDCLETSKNDFTKLL
ATFLIQLERRKGVQSSGIMLTFWLVALVCALAILRSKIMTALKEDAQVDLFRDITFYVYFSLLLIQLVLSCFSDRSPLFSETIHDPNPCP
ESSASFLSRITFWWITGLIVRGYRQPLEGSDLWSLNKEDTSEQVVPVLVKNWKKECAKTRKQPVKVVYSSKDPAQPKESSKVDANEEVEA
LIVKSPQKEWNPSLFKVLYKTFGPYFLMSFFFKAIHDLMMFSGPQILKLLIKFVNDTKAPDWQGYFYTVLLFVTACLQTLVLHQYFHICF
VSGMRIKTAVIGAVYRKALVITNSARKSSTVGEIVNLMSVDAQRFMDLATYINMIWSAPLQVILALYLLWLNLGPSVLAGVAVMVLMVPV
NAVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFKDKVLAIRQEELKVLKKSAYLSAVGTFTWVCTPFLVALCTFAVYV
TIDENNILDAQTAFVSLALFNILRFPLNILPMVISSIVQASVSLKRLRIFLSHEELEPDSIERRPVKDGGGTNSITVRNATFTWARSDPP
TLNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVAIKGSVAYVPQQAWIQNDSLRENILFGCQLEEPYYRSVIQACALLPD
LEILPSGDRTEIGEKTRILVTHSMSYLPQVDVIIVMSGGKISEMGSYQELLARDGAFAEFLRTYASTEQEQDAEENGVTGVSGPGKEAKQ
MENGMLVTDSAGKQLQRQLSSSSSYSGDISRHHNSTAELQKAEAKKEETWKLMEADKAQTGQVKLSVYWDYMKAIGLFISFLSIFLFMCN
HVSALASNYWLSLWTDDPIVNGTQEHTKVRLSVYGALGISQGIAVFGYSMAVSIGGILASRCLHVDLLHSILRSPMSFFERTPSGNLVNR
FSKELDTVDSMIPEVIKMFMGSLFNVIGACIVILLATPIAAIIIPPLGLIYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVI
RAFEEQERFIHQSDLKVDENQKAYYPSIVANRWLAVRLECVGNCIVLFAALFAVISRHSLSAGLVGLSVSYSLQVTTYLNWLVRMSSEME
TNIVAVERLKEYSETEKEAPWQIQETAPPSSWPQVGRVEFRNYCLRYREDLDFVLRHINVTINGGEKVGIVGRTGAGKSSLTLGLFRINE
SAEGEIIIDGINIAKIGLHDLRFKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWTSLELAHLKDFVSALPDKLDHECAEGGENLSVGQR
QLVCLARALLRKTKILVLDEATAAVDLETDDLIQSTIRTQFEDCTVLTIAHRLNTIMDYTRVIVLDKGEIQEYGAPSDLLQQRGLFYSMA

--------------------------------------------------------------

>52377_52377_9_MDM1-ABCC1_MDM1_chr12_68707223_ENST00000411698_ABCC1_chr16_16108348_ENST00000349029_length(amino acids)=1837AA_BP=538
MPVRFKGLSEYQRNFLWKKSYLSESCNSSVGRKYPWAGLRSDQLGITKEPSFISKRRVPYHDPQISKSLEWNGAISESNVVASPEPEAPE
TPKSQEAEQKDVTQERVHSLEASRVPKRTRSHSADSRAEGASDVENNEGVTNHTPVNENVELEHSTKVLSENVDNGVFHNKSQFVPPFKG
NSVIHETEYKRNFKGLSPVKEPKLRNDLRENRNLETVSPERKSNKIDDRLKLEAEMELKDLHQPKRKLTPWKHQRLGKVNSEYRAKFLSP
AQYLYKAGAWTHVKGNMPNQGSLNAMWYAEVKELREKAEFYRKRVQGTHFSRDHLNQILSDSNCCWDVSSTTSSEGTVSSNIRALDLAGD
PTSHKTLQKCPSTEPEEKGNIVEEQPQKNTTEKLGVSAPTIPVRRRLAWDTENTSEDVQKQPGEKEEEDDNEEEGDRKTGKQAFMGEQEK
LDVREKSKADKMKEGSDSSVSSEKGGRLPTPKLRELGGIQRTHHDLTTPAVGGAVLVSPSKMKPPAPEQRKRMTSQDCLETSKNDFTKLL
ATFLIQLERRKGVQSSGIMLTFWLVALVCALAILRSKIMTALKEDAQVDLFRDITFYVYFSLLLIQLVLSCFSDRSPLFSETIHDPNPCP
ESSASFLSRITFWWITGLIVRGYRQPLEGSDLWSLNKEDTSEQVVPVLVKNWKKECAKTRKQPVKVVYSSKDPAQPKESSKVDANEEVEA
LIVKSPQKEWNPSLFKVLYKTFGPYFLMSFFFKAIHDLMMFSGPQILKLLIKFVNDTKAPDWQGYFYTVLLFVTACLQTLVLHQYFHICF
VSGMRIKTAVIGAVYRKALVITNSARKSSTVGEIVNLMSVDAQRFMDLATYINMIWSAPLQVILALYLLWLNLGPSVLAGVAVMVLMVPV
NAVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFKDKVLAIRQEELKVLKKSAYLSAVGTFTWVCTPFLVALCTFAVYV
TIDENNILDAQTAFVSLALFNILRFPLNILPMVISSIVQASVSLKRLRIFLSHEELEPDSIERRPVKDGGGTNSITVRNATFTWARSDPP
TLNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVAIKTRILVTHSMSYLPQVDVIIVMSGGKISEMGSYQELLARDGAFAE
FLRTYASTEQEQDAEENGVTGVSGPGKEAKQMENGMLVTDSAGKQLQRQLSSSSSYSGDISRHHNSTAELQKAEAKKEETWKLMEADKAQ
TGQVKLSVYWDYMKAIGLFISFLSIFLFMCNHVSALASNYWLSLWTDDPIVNGTQEHTKVRLSVYGALGISQGIAVFGYSMAVSIGGILA
SRCLHVDLLHSILRSPMSFFERTPSGNLVNRFSKELDTVDSMIPEVIKMFMGSLFNVIGACIVILLATPIAAIIIPPLGLIYFFVQRFYV
ASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIHQSDLKVDENQKAYYPSIVANRWLAVRLECVGNCIVLFAALFAVISRHS
LSAGLVGLSVSYSLQVTTYLNWLVRMSSEMETNIVAVERLKEYSETEKEAPWQIQETAPPSSWPQVGRVEFRNYCLRYREDLDFVLRHIN
VTINGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGINIAKIGLHDLRFKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWTSLE
LAHLKDFVSALPDKLDHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDDLIQSTIRTQFEDCTVLTIAHRLNTIMDY

--------------------------------------------------------------

>52377_52377_10_MDM1-ABCC1_MDM1_chr12_68707223_ENST00000411698_ABCC1_chr16_16108348_ENST00000351154_length(amino acids)=1893AA_BP=538
MPVRFKGLSEYQRNFLWKKSYLSESCNSSVGRKYPWAGLRSDQLGITKEPSFISKRRVPYHDPQISKSLEWNGAISESNVVASPEPEAPE
TPKSQEAEQKDVTQERVHSLEASRVPKRTRSHSADSRAEGASDVENNEGVTNHTPVNENVELEHSTKVLSENVDNGVFHNKSQFVPPFKG
NSVIHETEYKRNFKGLSPVKEPKLRNDLRENRNLETVSPERKSNKIDDRLKLEAEMELKDLHQPKRKLTPWKHQRLGKVNSEYRAKFLSP
AQYLYKAGAWTHVKGNMPNQGSLNAMWYAEVKELREKAEFYRKRVQGTHFSRDHLNQILSDSNCCWDVSSTTSSEGTVSSNIRALDLAGD
PTSHKTLQKCPSTEPEEKGNIVEEQPQKNTTEKLGVSAPTIPVRRRLAWDTENTSEDVQKQPGEKEEEDDNEEEGDRKTGKQAFMGEQEK
LDVREKSKADKMKEGSDSSVSSEKGGRLPTPKLRELGGIQRTHHDLTTPAVGGAVLVSPSKMKPPAPEQRKRMTSQDCLETSKNDFTKLL
ATFLIQLERRKGVQSSGIMLTFWLVALVCALAILRSKIMTALKEDAQVDLFRDITFYVYFSLLLIQLVLSCFSDRSPLFSETIHDPNPCP
ESSASFLSRITFWWITGLIVRGYRQPLEGSDLWSLNKEDTSEQVVPVLVKNWKKECAKTRKQPVKVVYSSKDPAQPKESSKVDANEEVEA
LIVKSPQKEWNPSLFKVLYKTFGPYFLMSFFFKAIHDLMMFSGPQILKLLIKFVNDTKAPDWQGYFYTVLLFVTACLQTLVLHQYFHICF
VSGMRIKTAVIGAVYRKALVITNSARKSSTVGEIVNLMSVDAQRFMDLATYINMIWSAPLQVILALYLLWLNLGPSVLAGVAVMVLMVPV
NAVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFKDKVLAIRQEELKVLKKSAYLSAVGTFTWVCTPFLVALCTFAVYV
TIDENNILDAQTAFVSLALFNILRFPLNILPMVISSIVQASVSLKRLRIFLSHEELEPDSIERRPVKDGGGTNSITVRNATFTWARSDPP
TLNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVAIKGVNLSGGQKQRVSLARAVYSNADIYLFDDPLSAVDAHVGKHIFE
NVIGPKGMLKNKTRILVTHSMSYLPQVDVIIVMSGGKISEMGSYQELLARDGAFAEFLRTYASTEQEQDAEENGVTGVSGPGKEAKQMEN
GMLVTDSAGKQLQRQLSSSSSYSGDISRHHNSTAELQKAEAKKEETWKLMEADKAQTGQVKLSVYWDYMKAIGLFISFLSIFLFMCNHVS
ALASNYWLSLWTDDPIVNGTQEHTKVRLSVYGALGISQGIAVFGYSMAVSIGGILASRCLHVDLLHSILRSPMSFFERTPSGNLVNRFSK
ELDTVDSMIPEVIKMFMGSLFNVIGACIVILLATPIAAIIIPPLGLIYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAF
EEQERFIHQSDLKVDENQKAYYPSIVANRWLAVRLECVGNCIVLFAALFAVISRHSLSAGLVGLSVSYSLQVTTYLNWLVRMSSEMETNI
VAVERLKEYSETEKEAPWQIQETAPPSSWPQVGRVEFRNYCLRYREDLDFVLRHINVTINGGEKVGIVGRTGAGKSSLTLGLFRINESAE
GEIIIDGINIAKIGLHDLRFKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWTSLELAHLKDFVSALPDKLDHECAEGGENLSVGQRQLV
CLARALLRKTKILVLDEATAAVDLETDDLIQSTIRTQFEDCTVLTIAHRLNTIMDYTRVIVLDKGEIQEYGAPSDLLQQRGLFYSMAKDA

--------------------------------------------------------------

>52377_52377_11_MDM1-ABCC1_MDM1_chr12_68707223_ENST00000411698_ABCC1_chr16_16108348_ENST00000399408_length(amino acids)=1962AA_BP=538
MPVRFKGLSEYQRNFLWKKSYLSESCNSSVGRKYPWAGLRSDQLGITKEPSFISKRRVPYHDPQISKSLEWNGAISESNVVASPEPEAPE
TPKSQEAEQKDVTQERVHSLEASRVPKRTRSHSADSRAEGASDVENNEGVTNHTPVNENVELEHSTKVLSENVDNGVFHNKSQFVPPFKG
NSVIHETEYKRNFKGLSPVKEPKLRNDLRENRNLETVSPERKSNKIDDRLKLEAEMELKDLHQPKRKLTPWKHQRLGKVNSEYRAKFLSP
AQYLYKAGAWTHVKGNMPNQGSLNAMWYAEVKELREKAEFYRKRVQGTHFSRDHLNQILSDSNCCWDVSSTTSSEGTVSSNIRALDLAGD
PTSHKTLQKCPSTEPEEKGNIVEEQPQKNTTEKLGVSAPTIPVRRRLAWDTENTSEDVQKQPGEKEEEDDNEEEGDRKTGKQAFMGEQEK
LDVREKSKADKMKEGSDSSVSSEKGGRLPTPKLRELGGIQRTHHDLTTPAVGGAVLVSPSKMKPPAPEQRKRMTSQDCLETSKNDFTKLL
ATFLIQLERRKGVQSSGIMLTFWLVALVCALAILRSKIMTALKEDAQVDLFRDITFYVYFSLLLIQLVLSCFSDRSPLFSETIHDPNPCP
ESSASFLSRITFWWITGLIVRGYRQPLEGSDLWSLNKEDTSEQVVPVLVKNWKKECAKTRKQPVKVVYSSKDPAQPKESSKVDANEEVEA
LIVKSPQKEWNPSLFKVLYKTFGPYFLMSFFFKAIHDLMMFSGPQILKLLIKFVNDTKAPDWQGYFYTVLLFVTACLQTLVLHQYFHICF
VSGMRIKTAVIGAVYRKALVITNSARKSSTVGEIVNLMSVDAQRFMDLATYINMIWSAPLQVILALYLLWLNLGPSVLAGVAVMVLMVPV
NAVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFKDKVLAIRQEELKVLKKSAYLSAVGTFTWVCTPFLVALCTFAVYV
TIDENNILDAQTAFVSLALFNILRFPLNILPMVISSIVQASVSLKRLRIFLSHEELEPDSIERRPVKDGGGTNSITVRNATFTWARSDPP
TLNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVAIKGSVAYVPQQAWIQNDSLRENILFGCQLEEPYYRSVIQACALLPD
LEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYSNADIYLFDDPLSAVDAHVGKHIFENVIGPKGMLKNKTRILVTHSMSYLPQVDVII
VMSGGKISEMGSYQELLARDGAFAEFLRTYASTEQEQDAEENGSTVMDEEEAGVTGVSGPGKEAKQMENGMLVTDSAGKQLQRQLSSSSS
YSGDISRHHNSTAELQKAEAKKEETWKLMEADKAQTGQVKLSVYWDYMKAIGLFISFLSIFLFMCNHVSALASNYWLSLWTDDPIVNGTQ
EHTKVRLSVYGALGISQGIAVFGYSMAVSIGGILASRCLHVDLLHSILRSPMSFFERTPSGNLVNRFSKELDTVDSMIPEVIKMFMGSLF
NVIGACIVILLATPIAAIIIPPLGLIYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIHQSDLKVDENQKAY
YPSIVANRWLAVRLECVGNCIVLFAALFAVISRHSLSAGLVGLSVSYSLQVTTYLNWLVRMSSEMETNIVAVERLKEYSETEKEAPWQIQ
ETAPPSSWPQVGRVEFRNYCLRYREDLDFVLRHINVTINGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGINIAKIGLHDLRFK
ITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWTSLELAHLKDFVSALPDKLDHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAA

--------------------------------------------------------------

>52377_52377_12_MDM1-ABCC1_MDM1_chr12_68707223_ENST00000411698_ABCC1_chr16_16108348_ENST00000399410_length(amino acids)=1952AA_BP=538
MPVRFKGLSEYQRNFLWKKSYLSESCNSSVGRKYPWAGLRSDQLGITKEPSFISKRRVPYHDPQISKSLEWNGAISESNVVASPEPEAPE
TPKSQEAEQKDVTQERVHSLEASRVPKRTRSHSADSRAEGASDVENNEGVTNHTPVNENVELEHSTKVLSENVDNGVFHNKSQFVPPFKG
NSVIHETEYKRNFKGLSPVKEPKLRNDLRENRNLETVSPERKSNKIDDRLKLEAEMELKDLHQPKRKLTPWKHQRLGKVNSEYRAKFLSP
AQYLYKAGAWTHVKGNMPNQGSLNAMWYAEVKELREKAEFYRKRVQGTHFSRDHLNQILSDSNCCWDVSSTTSSEGTVSSNIRALDLAGD
PTSHKTLQKCPSTEPEEKGNIVEEQPQKNTTEKLGVSAPTIPVRRRLAWDTENTSEDVQKQPGEKEEEDDNEEEGDRKTGKQAFMGEQEK
LDVREKSKADKMKEGSDSSVSSEKGGRLPTPKLRELGGIQRTHHDLTTPAVGGAVLVSPSKMKPPAPEQRKRMTSQDCLETSKNDFTKLL
ATFLIQLERRKGVQSSGIMLTFWLVALVCALAILRSKIMTALKEDAQVDLFRDITFYVYFSLLLIQLVLSCFSDRSPLFSETIHDPNPCP
ESSASFLSRITFWWITGLIVRGYRQPLEGSDLWSLNKEDTSEQVVPVLVKNWKKECAKTRKQPVKVVYSSKDPAQPKESSKVDANEEVEA
LIVKSPQKEWNPSLFKVLYKTFGPYFLMSFFFKAIHDLMMFSGPQILKLLIKFVNDTKAPDWQGYFYTVLLFVTACLQTLVLHQYFHICF
VSGMRIKTAVIGAVYRKALVITNSARKSSTVGEIVNLMSVDAQRFMDLATYINMIWSAPLQVILALYLLWLNLGPSVLAGVAVMVLMVPV
NAVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFKDKVLAIRQEELKVLKKSAYLSAVGTFTWVCTPFLVALCTFAVYV
TIDENNILDAQTAFVSLALFNILRFPLNILPMVISSIVQASVSLKRLRIFLSHEELEPDSIERRPVKDGGGTNSITVRNATFTWARSDPP
TLNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVAIKGSVAYVPQQAWIQNDSLRENILFGCQLEEPYYRSVIQACALLPD
LEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYSNADIYLFDDPLSAVDAHVGKHIFENVIGPKGMLKNKTRILVTHSMSYLPQVDVII
VMSGGKISEMGSYQELLARDGAFAEFLRTYASTEQEQDAEENGVTGVSGPGKEAKQMENGMLVTDSAGKQLQRQLSSSSSYSGDISRHHN
STAELQKAEAKKEETWKLMEADKAQTGQVKLSVYWDYMKAIGLFISFLSIFLFMCNHVSALASNYWLSLWTDDPIVNGTQEHTKVRLSVY
GALGISQGIAVFGYSMAVSIGGILASRCLHVDLLHSILRSPMSFFERTPSGNLVNRFSKELDTVDSMIPEVIKMFMGSLFNVIGACIVIL
LATPIAAIIIPPLGLIYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIHQSDLKVDENQKAYYPSIVANRWL
AVRLECVGNCIVLFAALFAVISRHSLSAGLVGLSVSYSLQVTTYLNWLVRMSSEMETNIVAVERLKEYSETEKEAPWQIQETAPPSSWPQ
VGRVEFRNYCLRYREDLDFVLRHINVTINGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGINIAKIGLHDLRFKITIIPQDPVL
FSGSLRMNLDPFSQYSDEEVWTSLELAHLKDFVSALPDKLDHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDDLIQ

--------------------------------------------------------------

Top

Fusion Protein Functional Features


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr12:68707223/chr16:16108348)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
MDM1

Q8TC05

ABCC1

Q96J66

FUNCTION: Microtubule-binding protein that negatively regulates centriole duplication. Binds to and stabilizes microtubules (PubMed:26337392). {ECO:0000269|PubMed:26337392}.FUNCTION: ATP-dependent transporter of the ATP-binding cassette (ABC) family that actively extrudes physiological compounds, and xenobiotics from cells. Participates in physiological processes involving bile acids, conjugated steroids and cyclic nucleotides (PubMed:12764137, PubMed:15537867). Stimulates the ATP-dependent uptake of a range of physiological lipophilic anions, including the glutathione S-conjugates leukotriene C4 and dinitrophenyl S-glutathione, steroid sulfates such as dehydroepiandrosterone 3-sulfate (DHEAS) and estrone 3-sulfate, glucuronides such as estradiol 17-beta-D-glucuronide (E(2)17betaG), the monoanionic bile acids glycocholate and taurocholate, and methotrexate (PubMed:15537867, PubMed:25896536). Enhances also the cellular extrusion of cAMP and cGMP (PubMed:12764137, PubMed:15537867). Confers resistance to anticancer drugs, such as 5-fluorouracil (5-FU) and methotrexate (PubMed:25896536, PubMed:15537867, PubMed:12764137). Probably functions to secrete earwax (PubMed:16444273, PubMed:19383836). Required for the secretion of components contributing to axillary odor formation (PubMed:19710689, PubMed:12764137, PubMed:15537867, PubMed:16444273, PubMed:19383836, PubMed:25896536). {ECO:0000269|PubMed:12764137, ECO:0000269|PubMed:15537867, ECO:0000269|PubMed:16444273, ECO:0000269|PubMed:19383836, ECO:0000269|PubMed:19710689, ECO:0000269|PubMed:25896536}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

* Minus value of BPloci means that the break pointn is located before the CDS.
- Retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneABCC1chr12:68707223chr16:16108348ENST000003451482301293_1527117.01467.0DomainABC transporter 2
TgeneABCC1chr12:68707223chr16:16108348ENST00000345148230325_608117.01467.0DomainABC transmembrane type-1 1
TgeneABCC1chr12:68707223chr16:16108348ENST00000345148230644_868117.01467.0DomainABC transporter 1
TgeneABCC1chr12:68707223chr16:16108348ENST00000345148230975_1256117.01467.0DomainABC transmembrane type-1 2
TgeneABCC1chr12:68707223chr16:16108348ENST000003463702301293_1527117.01476.0DomainABC transporter 2
TgeneABCC1chr12:68707223chr16:16108348ENST00000346370230325_608117.01476.0DomainABC transmembrane type-1 1
TgeneABCC1chr12:68707223chr16:16108348ENST00000346370230644_868117.01476.0DomainABC transporter 1
TgeneABCC1chr12:68707223chr16:16108348ENST00000346370230975_1256117.01476.0DomainABC transmembrane type-1 2
TgeneABCC1chr12:68707223chr16:16108348ENST000003490292291293_1527117.01417.0DomainABC transporter 2
TgeneABCC1chr12:68707223chr16:16108348ENST00000349029229325_608117.01417.0DomainABC transmembrane type-1 1
TgeneABCC1chr12:68707223chr16:16108348ENST00000349029229644_868117.01417.0DomainABC transporter 1
TgeneABCC1chr12:68707223chr16:16108348ENST00000349029229975_1256117.01417.0DomainABC transmembrane type-1 2
TgeneABCC1chr12:68707223chr16:16108348ENST000003511542301293_1527117.01473.0DomainABC transporter 2
TgeneABCC1chr12:68707223chr16:16108348ENST00000351154230325_608117.01473.0DomainABC transmembrane type-1 1
TgeneABCC1chr12:68707223chr16:16108348ENST00000351154230644_868117.01473.0DomainABC transporter 1
TgeneABCC1chr12:68707223chr16:16108348ENST00000351154230975_1256117.01473.0DomainABC transmembrane type-1 2
TgeneABCC1chr12:68707223chr16:16108348ENST000003994082321293_1527117.01542.0DomainABC transporter 2
TgeneABCC1chr12:68707223chr16:16108348ENST00000399408232325_608117.01542.0DomainABC transmembrane type-1 1
TgeneABCC1chr12:68707223chr16:16108348ENST00000399408232644_868117.01542.0DomainABC transporter 1
TgeneABCC1chr12:68707223chr16:16108348ENST00000399408232975_1256117.01542.0DomainABC transmembrane type-1 2
TgeneABCC1chr12:68707223chr16:16108348ENST000003994102311293_1527117.01532.0DomainABC transporter 2
TgeneABCC1chr12:68707223chr16:16108348ENST00000399410231325_608117.01532.0DomainABC transmembrane type-1 1
TgeneABCC1chr12:68707223chr16:16108348ENST00000399410231644_868117.01532.0DomainABC transporter 1
TgeneABCC1chr12:68707223chr16:16108348ENST00000399410231975_1256117.01532.0DomainABC transmembrane type-1 2
TgeneABCC1chr12:68707223chr16:16108348ENST000003451482301327_1334117.01467.0Nucleotide bindingATP 2
TgeneABCC1chr12:68707223chr16:16108348ENST00000345148230678_685117.01467.0Nucleotide bindingNote=ATP 1
TgeneABCC1chr12:68707223chr16:16108348ENST000003463702301327_1334117.01476.0Nucleotide bindingATP 2
TgeneABCC1chr12:68707223chr16:16108348ENST00000346370230678_685117.01476.0Nucleotide bindingNote=ATP 1
TgeneABCC1chr12:68707223chr16:16108348ENST000003490292291327_1334117.01417.0Nucleotide bindingATP 2
TgeneABCC1chr12:68707223chr16:16108348ENST00000349029229678_685117.01417.0Nucleotide bindingNote=ATP 1
TgeneABCC1chr12:68707223chr16:16108348ENST000003511542301327_1334117.01473.0Nucleotide bindingATP 2
TgeneABCC1chr12:68707223chr16:16108348ENST00000351154230678_685117.01473.0Nucleotide bindingNote=ATP 1
TgeneABCC1chr12:68707223chr16:16108348ENST000003994082321327_1334117.01542.0Nucleotide bindingATP 2
TgeneABCC1chr12:68707223chr16:16108348ENST00000399408232678_685117.01542.0Nucleotide bindingNote=ATP 1
TgeneABCC1chr12:68707223chr16:16108348ENST000003994102311327_1334117.01532.0Nucleotide bindingATP 2
TgeneABCC1chr12:68707223chr16:16108348ENST00000399410231678_685117.01532.0Nucleotide bindingNote=ATP 1
TgeneABCC1chr12:68707223chr16:16108348ENST000003451482301047_1089117.01467.0Topological domainNote=Cytoplasmic
TgeneABCC1chr12:68707223chr16:16108348ENST000003451482301111_1111117.01467.0Topological domainNote=Extracellular
TgeneABCC1chr12:68707223chr16:16108348ENST000003451482301133_1203117.01467.0Topological domainNote=Cytoplasmic
TgeneABCC1chr12:68707223chr16:16108348ENST000003451482301225_1226117.01467.0Topological domainNote=Extracellular
TgeneABCC1chr12:68707223chr16:16108348ENST00000345148230122_133117.01467.0Topological domainNote=Cytoplasmic
TgeneABCC1chr12:68707223chr16:16108348ENST000003451482301248_1531117.01467.0Topological domainNote=Cytoplasmic
TgeneABCC1chr12:68707223chr16:16108348ENST00000345148230155_172117.01467.0Topological domainNote=Extracellular
TgeneABCC1chr12:68707223chr16:16108348ENST00000345148230194_316117.01467.0Topological domainNote=Cytoplasmic
TgeneABCC1chr12:68707223chr16:16108348ENST00000345148230338_363117.01467.0Topological domainNote=Extracellular
TgeneABCC1chr12:68707223chr16:16108348ENST00000345148230385_440117.01467.0Topological domainNote=Cytoplasmic
TgeneABCC1chr12:68707223chr16:16108348ENST00000345148230462_464117.01467.0Topological domainNote=Extracellular
TgeneABCC1chr12:68707223chr16:16108348ENST00000345148230486_547117.01467.0Topological domainNote=Cytoplasmic
TgeneABCC1chr12:68707223chr16:16108348ENST00000345148230569_590117.01467.0Topological domainNote=Extracellular
TgeneABCC1chr12:68707223chr16:16108348ENST00000345148230612_967117.01467.0Topological domainNote=Cytoplasmic
TgeneABCC1chr12:68707223chr16:16108348ENST00000345148230989_1025117.01467.0Topological domainNote=Extracellular
TgeneABCC1chr12:68707223chr16:16108348ENST000003463702301047_1089117.01476.0Topological domainNote=Cytoplasmic
TgeneABCC1chr12:68707223chr16:16108348ENST000003463702301111_1111117.01476.0Topological domainNote=Extracellular
TgeneABCC1chr12:68707223chr16:16108348ENST000003463702301133_1203117.01476.0Topological domainNote=Cytoplasmic
TgeneABCC1chr12:68707223chr16:16108348ENST000003463702301225_1226117.01476.0Topological domainNote=Extracellular
TgeneABCC1chr12:68707223chr16:16108348ENST00000346370230122_133117.01476.0Topological domainNote=Cytoplasmic
TgeneABCC1chr12:68707223chr16:16108348ENST000003463702301248_1531117.01476.0Topological domainNote=Cytoplasmic
TgeneABCC1chr12:68707223chr16:16108348ENST00000346370230155_172117.01476.0Topological domainNote=Extracellular
TgeneABCC1chr12:68707223chr16:16108348ENST00000346370230194_316117.01476.0Topological domainNote=Cytoplasmic
TgeneABCC1chr12:68707223chr16:16108348ENST00000346370230338_363117.01476.0Topological domainNote=Extracellular
TgeneABCC1chr12:68707223chr16:16108348ENST00000346370230385_440117.01476.0Topological domainNote=Cytoplasmic
TgeneABCC1chr12:68707223chr16:16108348ENST00000346370230462_464117.01476.0Topological domainNote=Extracellular
TgeneABCC1chr12:68707223chr16:16108348ENST00000346370230486_547117.01476.0Topological domainNote=Cytoplasmic
TgeneABCC1chr12:68707223chr16:16108348ENST00000346370230569_590117.01476.0Topological domainNote=Extracellular
TgeneABCC1chr12:68707223chr16:16108348ENST00000346370230612_967117.01476.0Topological domainNote=Cytoplasmic
TgeneABCC1chr12:68707223chr16:16108348ENST00000346370230989_1025117.01476.0Topological domainNote=Extracellular
TgeneABCC1chr12:68707223chr16:16108348ENST000003490292291047_1089117.01417.0Topological domainNote=Cytoplasmic
TgeneABCC1chr12:68707223chr16:16108348ENST000003490292291111_1111117.01417.0Topological domainNote=Extracellular
TgeneABCC1chr12:68707223chr16:16108348ENST000003490292291133_1203117.01417.0Topological domainNote=Cytoplasmic
TgeneABCC1chr12:68707223chr16:16108348ENST000003490292291225_1226117.01417.0Topological domainNote=Extracellular
TgeneABCC1chr12:68707223chr16:16108348ENST00000349029229122_133117.01417.0Topological domainNote=Cytoplasmic
TgeneABCC1chr12:68707223chr16:16108348ENST000003490292291248_1531117.01417.0Topological domainNote=Cytoplasmic
TgeneABCC1chr12:68707223chr16:16108348ENST00000349029229155_172117.01417.0Topological domainNote=Extracellular
TgeneABCC1chr12:68707223chr16:16108348ENST00000349029229194_316117.01417.0Topological domainNote=Cytoplasmic
TgeneABCC1chr12:68707223chr16:16108348ENST00000349029229338_363117.01417.0Topological domainNote=Extracellular
TgeneABCC1chr12:68707223chr16:16108348ENST00000349029229385_440117.01417.0Topological domainNote=Cytoplasmic
TgeneABCC1chr12:68707223chr16:16108348ENST00000349029229462_464117.01417.0Topological domainNote=Extracellular
TgeneABCC1chr12:68707223chr16:16108348ENST00000349029229486_547117.01417.0Topological domainNote=Cytoplasmic
TgeneABCC1chr12:68707223chr16:16108348ENST00000349029229569_590117.01417.0Topological domainNote=Extracellular
TgeneABCC1chr12:68707223chr16:16108348ENST00000349029229612_967117.01417.0Topological domainNote=Cytoplasmic
TgeneABCC1chr12:68707223chr16:16108348ENST00000349029229989_1025117.01417.0Topological domainNote=Extracellular
TgeneABCC1chr12:68707223chr16:16108348ENST000003511542301047_1089117.01473.0Topological domainNote=Cytoplasmic
TgeneABCC1chr12:68707223chr16:16108348ENST000003511542301111_1111117.01473.0Topological domainNote=Extracellular
TgeneABCC1chr12:68707223chr16:16108348ENST000003511542301133_1203117.01473.0Topological domainNote=Cytoplasmic
TgeneABCC1chr12:68707223chr16:16108348ENST000003511542301225_1226117.01473.0Topological domainNote=Extracellular
TgeneABCC1chr12:68707223chr16:16108348ENST00000351154230122_133117.01473.0Topological domainNote=Cytoplasmic
TgeneABCC1chr12:68707223chr16:16108348ENST000003511542301248_1531117.01473.0Topological domainNote=Cytoplasmic
TgeneABCC1chr12:68707223chr16:16108348ENST00000351154230155_172117.01473.0Topological domainNote=Extracellular
TgeneABCC1chr12:68707223chr16:16108348ENST00000351154230194_316117.01473.0Topological domainNote=Cytoplasmic
TgeneABCC1chr12:68707223chr16:16108348ENST00000351154230338_363117.01473.0Topological domainNote=Extracellular
TgeneABCC1chr12:68707223chr16:16108348ENST00000351154230385_440117.01473.0Topological domainNote=Cytoplasmic
TgeneABCC1chr12:68707223chr16:16108348ENST00000351154230462_464117.01473.0Topological domainNote=Extracellular
TgeneABCC1chr12:68707223chr16:16108348ENST00000351154230486_547117.01473.0Topological domainNote=Cytoplasmic
TgeneABCC1chr12:68707223chr16:16108348ENST00000351154230569_590117.01473.0Topological domainNote=Extracellular
TgeneABCC1chr12:68707223chr16:16108348ENST00000351154230612_967117.01473.0Topological domainNote=Cytoplasmic
TgeneABCC1chr12:68707223chr16:16108348ENST00000351154230989_1025117.01473.0Topological domainNote=Extracellular
TgeneABCC1chr12:68707223chr16:16108348ENST000003994082321047_1089117.01542.0Topological domainNote=Cytoplasmic
TgeneABCC1chr12:68707223chr16:16108348ENST000003994082321111_1111117.01542.0Topological domainNote=Extracellular
TgeneABCC1chr12:68707223chr16:16108348ENST000003994082321133_1203117.01542.0Topological domainNote=Cytoplasmic
TgeneABCC1chr12:68707223chr16:16108348ENST000003994082321225_1226117.01542.0Topological domainNote=Extracellular
TgeneABCC1chr12:68707223chr16:16108348ENST00000399408232122_133117.01542.0Topological domainNote=Cytoplasmic
TgeneABCC1chr12:68707223chr16:16108348ENST000003994082321248_1531117.01542.0Topological domainNote=Cytoplasmic
TgeneABCC1chr12:68707223chr16:16108348ENST00000399408232155_172117.01542.0Topological domainNote=Extracellular
TgeneABCC1chr12:68707223chr16:16108348ENST00000399408232194_316117.01542.0Topological domainNote=Cytoplasmic
TgeneABCC1chr12:68707223chr16:16108348ENST00000399408232338_363117.01542.0Topological domainNote=Extracellular
TgeneABCC1chr12:68707223chr16:16108348ENST00000399408232385_440117.01542.0Topological domainNote=Cytoplasmic
TgeneABCC1chr12:68707223chr16:16108348ENST00000399408232462_464117.01542.0Topological domainNote=Extracellular
TgeneABCC1chr12:68707223chr16:16108348ENST00000399408232486_547117.01542.0Topological domainNote=Cytoplasmic
TgeneABCC1chr12:68707223chr16:16108348ENST00000399408232569_590117.01542.0Topological domainNote=Extracellular
TgeneABCC1chr12:68707223chr16:16108348ENST00000399408232612_967117.01542.0Topological domainNote=Cytoplasmic
TgeneABCC1chr12:68707223chr16:16108348ENST00000399408232989_1025117.01542.0Topological domainNote=Extracellular
TgeneABCC1chr12:68707223chr16:16108348ENST000003994102311047_1089117.01532.0Topological domainNote=Cytoplasmic
TgeneABCC1chr12:68707223chr16:16108348ENST000003994102311111_1111117.01532.0Topological domainNote=Extracellular
TgeneABCC1chr12:68707223chr16:16108348ENST000003994102311133_1203117.01532.0Topological domainNote=Cytoplasmic
TgeneABCC1chr12:68707223chr16:16108348ENST000003994102311225_1226117.01532.0Topological domainNote=Extracellular
TgeneABCC1chr12:68707223chr16:16108348ENST00000399410231122_133117.01532.0Topological domainNote=Cytoplasmic
TgeneABCC1chr12:68707223chr16:16108348ENST000003994102311248_1531117.01532.0Topological domainNote=Cytoplasmic
TgeneABCC1chr12:68707223chr16:16108348ENST00000399410231155_172117.01532.0Topological domainNote=Extracellular
TgeneABCC1chr12:68707223chr16:16108348ENST00000399410231194_316117.01532.0Topological domainNote=Cytoplasmic
TgeneABCC1chr12:68707223chr16:16108348ENST00000399410231338_363117.01532.0Topological domainNote=Extracellular
TgeneABCC1chr12:68707223chr16:16108348ENST00000399410231385_440117.01532.0Topological domainNote=Cytoplasmic
TgeneABCC1chr12:68707223chr16:16108348ENST00000399410231462_464117.01532.0Topological domainNote=Extracellular
TgeneABCC1chr12:68707223chr16:16108348ENST00000399410231486_547117.01532.0Topological domainNote=Cytoplasmic
TgeneABCC1chr12:68707223chr16:16108348ENST00000399410231569_590117.01532.0Topological domainNote=Extracellular
TgeneABCC1chr12:68707223chr16:16108348ENST00000399410231612_967117.01532.0Topological domainNote=Cytoplasmic
TgeneABCC1chr12:68707223chr16:16108348ENST00000399410231989_1025117.01532.0Topological domainNote=Extracellular
TgeneABCC1chr12:68707223chr16:16108348ENST000003451482301026_1046117.01467.0TransmembraneNote=Helical%3B Name%3D13
TgeneABCC1chr12:68707223chr16:16108348ENST000003451482301090_1110117.01467.0TransmembraneNote=Helical%3B Name%3D14
TgeneABCC1chr12:68707223chr16:16108348ENST000003451482301112_1132117.01467.0TransmembraneNote=Helical%3B Name%3D15
TgeneABCC1chr12:68707223chr16:16108348ENST000003451482301204_1224117.01467.0TransmembraneNote=Helical%3B Name%3D16
TgeneABCC1chr12:68707223chr16:16108348ENST000003451482301227_1247117.01467.0TransmembraneNote=Helical%3B Name%3D17
TgeneABCC1chr12:68707223chr16:16108348ENST00000345148230134_154117.01467.0TransmembraneNote=Helical%3B Name%3D4
TgeneABCC1chr12:68707223chr16:16108348ENST00000345148230173_193117.01467.0TransmembraneNote=Helical%3B Name%3D5
TgeneABCC1chr12:68707223chr16:16108348ENST00000345148230317_337117.01467.0TransmembraneNote=Helical%3B Name%3D6
TgeneABCC1chr12:68707223chr16:16108348ENST00000345148230364_384117.01467.0TransmembraneNote=Helical%3B Name%3D7
TgeneABCC1chr12:68707223chr16:16108348ENST00000345148230441_461117.01467.0TransmembraneNote=Helical%3B Name%3D8
TgeneABCC1chr12:68707223chr16:16108348ENST00000345148230465_485117.01467.0TransmembraneNote=Helical%3B Name%3D9
TgeneABCC1chr12:68707223chr16:16108348ENST00000345148230548_568117.01467.0TransmembraneNote=Helical%3B Name%3D10
TgeneABCC1chr12:68707223chr16:16108348ENST00000345148230591_611117.01467.0TransmembraneNote=Helical%3B Name%3D11
TgeneABCC1chr12:68707223chr16:16108348ENST00000345148230968_988117.01467.0TransmembraneNote=Helical%3B Name%3D12
TgeneABCC1chr12:68707223chr16:16108348ENST000003463702301026_1046117.01476.0TransmembraneNote=Helical%3B Name%3D13
TgeneABCC1chr12:68707223chr16:16108348ENST000003463702301090_1110117.01476.0TransmembraneNote=Helical%3B Name%3D14
TgeneABCC1chr12:68707223chr16:16108348ENST000003463702301112_1132117.01476.0TransmembraneNote=Helical%3B Name%3D15
TgeneABCC1chr12:68707223chr16:16108348ENST000003463702301204_1224117.01476.0TransmembraneNote=Helical%3B Name%3D16
TgeneABCC1chr12:68707223chr16:16108348ENST000003463702301227_1247117.01476.0TransmembraneNote=Helical%3B Name%3D17
TgeneABCC1chr12:68707223chr16:16108348ENST00000346370230134_154117.01476.0TransmembraneNote=Helical%3B Name%3D4
TgeneABCC1chr12:68707223chr16:16108348ENST00000346370230173_193117.01476.0TransmembraneNote=Helical%3B Name%3D5
TgeneABCC1chr12:68707223chr16:16108348ENST00000346370230317_337117.01476.0TransmembraneNote=Helical%3B Name%3D6
TgeneABCC1chr12:68707223chr16:16108348ENST00000346370230364_384117.01476.0TransmembraneNote=Helical%3B Name%3D7
TgeneABCC1chr12:68707223chr16:16108348ENST00000346370230441_461117.01476.0TransmembraneNote=Helical%3B Name%3D8
TgeneABCC1chr12:68707223chr16:16108348ENST00000346370230465_485117.01476.0TransmembraneNote=Helical%3B Name%3D9
TgeneABCC1chr12:68707223chr16:16108348ENST00000346370230548_568117.01476.0TransmembraneNote=Helical%3B Name%3D10
TgeneABCC1chr12:68707223chr16:16108348ENST00000346370230591_611117.01476.0TransmembraneNote=Helical%3B Name%3D11
TgeneABCC1chr12:68707223chr16:16108348ENST00000346370230968_988117.01476.0TransmembraneNote=Helical%3B Name%3D12
TgeneABCC1chr12:68707223chr16:16108348ENST000003490292291026_1046117.01417.0TransmembraneNote=Helical%3B Name%3D13
TgeneABCC1chr12:68707223chr16:16108348ENST000003490292291090_1110117.01417.0TransmembraneNote=Helical%3B Name%3D14
TgeneABCC1chr12:68707223chr16:16108348ENST000003490292291112_1132117.01417.0TransmembraneNote=Helical%3B Name%3D15
TgeneABCC1chr12:68707223chr16:16108348ENST000003490292291204_1224117.01417.0TransmembraneNote=Helical%3B Name%3D16
TgeneABCC1chr12:68707223chr16:16108348ENST000003490292291227_1247117.01417.0TransmembraneNote=Helical%3B Name%3D17
TgeneABCC1chr12:68707223chr16:16108348ENST00000349029229134_154117.01417.0TransmembraneNote=Helical%3B Name%3D4
TgeneABCC1chr12:68707223chr16:16108348ENST00000349029229173_193117.01417.0TransmembraneNote=Helical%3B Name%3D5
TgeneABCC1chr12:68707223chr16:16108348ENST00000349029229317_337117.01417.0TransmembraneNote=Helical%3B Name%3D6
TgeneABCC1chr12:68707223chr16:16108348ENST00000349029229364_384117.01417.0TransmembraneNote=Helical%3B Name%3D7
TgeneABCC1chr12:68707223chr16:16108348ENST00000349029229441_461117.01417.0TransmembraneNote=Helical%3B Name%3D8
TgeneABCC1chr12:68707223chr16:16108348ENST00000349029229465_485117.01417.0TransmembraneNote=Helical%3B Name%3D9
TgeneABCC1chr12:68707223chr16:16108348ENST00000349029229548_568117.01417.0TransmembraneNote=Helical%3B Name%3D10
TgeneABCC1chr12:68707223chr16:16108348ENST00000349029229591_611117.01417.0TransmembraneNote=Helical%3B Name%3D11
TgeneABCC1chr12:68707223chr16:16108348ENST00000349029229968_988117.01417.0TransmembraneNote=Helical%3B Name%3D12
TgeneABCC1chr12:68707223chr16:16108348ENST000003511542301026_1046117.01473.0TransmembraneNote=Helical%3B Name%3D13
TgeneABCC1chr12:68707223chr16:16108348ENST000003511542301090_1110117.01473.0TransmembraneNote=Helical%3B Name%3D14
TgeneABCC1chr12:68707223chr16:16108348ENST000003511542301112_1132117.01473.0TransmembraneNote=Helical%3B Name%3D15
TgeneABCC1chr12:68707223chr16:16108348ENST000003511542301204_1224117.01473.0TransmembraneNote=Helical%3B Name%3D16
TgeneABCC1chr12:68707223chr16:16108348ENST000003511542301227_1247117.01473.0TransmembraneNote=Helical%3B Name%3D17
TgeneABCC1chr12:68707223chr16:16108348ENST00000351154230134_154117.01473.0TransmembraneNote=Helical%3B Name%3D4
TgeneABCC1chr12:68707223chr16:16108348ENST00000351154230173_193117.01473.0TransmembraneNote=Helical%3B Name%3D5
TgeneABCC1chr12:68707223chr16:16108348ENST00000351154230317_337117.01473.0TransmembraneNote=Helical%3B Name%3D6
TgeneABCC1chr12:68707223chr16:16108348ENST00000351154230364_384117.01473.0TransmembraneNote=Helical%3B Name%3D7
TgeneABCC1chr12:68707223chr16:16108348ENST00000351154230441_461117.01473.0TransmembraneNote=Helical%3B Name%3D8
TgeneABCC1chr12:68707223chr16:16108348ENST00000351154230465_485117.01473.0TransmembraneNote=Helical%3B Name%3D9
TgeneABCC1chr12:68707223chr16:16108348ENST00000351154230548_568117.01473.0TransmembraneNote=Helical%3B Name%3D10
TgeneABCC1chr12:68707223chr16:16108348ENST00000351154230591_611117.01473.0TransmembraneNote=Helical%3B Name%3D11
TgeneABCC1chr12:68707223chr16:16108348ENST00000351154230968_988117.01473.0TransmembraneNote=Helical%3B Name%3D12
TgeneABCC1chr12:68707223chr16:16108348ENST000003994082321026_1046117.01542.0TransmembraneNote=Helical%3B Name%3D13
TgeneABCC1chr12:68707223chr16:16108348ENST000003994082321090_1110117.01542.0TransmembraneNote=Helical%3B Name%3D14
TgeneABCC1chr12:68707223chr16:16108348ENST000003994082321112_1132117.01542.0TransmembraneNote=Helical%3B Name%3D15
TgeneABCC1chr12:68707223chr16:16108348ENST000003994082321204_1224117.01542.0TransmembraneNote=Helical%3B Name%3D16
TgeneABCC1chr12:68707223chr16:16108348ENST000003994082321227_1247117.01542.0TransmembraneNote=Helical%3B Name%3D17
TgeneABCC1chr12:68707223chr16:16108348ENST00000399408232134_154117.01542.0TransmembraneNote=Helical%3B Name%3D4
TgeneABCC1chr12:68707223chr16:16108348ENST00000399408232173_193117.01542.0TransmembraneNote=Helical%3B Name%3D5
TgeneABCC1chr12:68707223chr16:16108348ENST00000399408232317_337117.01542.0TransmembraneNote=Helical%3B Name%3D6
TgeneABCC1chr12:68707223chr16:16108348ENST00000399408232364_384117.01542.0TransmembraneNote=Helical%3B Name%3D7
TgeneABCC1chr12:68707223chr16:16108348ENST00000399408232441_461117.01542.0TransmembraneNote=Helical%3B Name%3D8
TgeneABCC1chr12:68707223chr16:16108348ENST00000399408232465_485117.01542.0TransmembraneNote=Helical%3B Name%3D9
TgeneABCC1chr12:68707223chr16:16108348ENST00000399408232548_568117.01542.0TransmembraneNote=Helical%3B Name%3D10
TgeneABCC1chr12:68707223chr16:16108348ENST00000399408232591_611117.01542.0TransmembraneNote=Helical%3B Name%3D11
TgeneABCC1chr12:68707223chr16:16108348ENST00000399408232968_988117.01542.0TransmembraneNote=Helical%3B Name%3D12
TgeneABCC1chr12:68707223chr16:16108348ENST000003994102311026_1046117.01532.0TransmembraneNote=Helical%3B Name%3D13
TgeneABCC1chr12:68707223chr16:16108348ENST000003994102311090_1110117.01532.0TransmembraneNote=Helical%3B Name%3D14
TgeneABCC1chr12:68707223chr16:16108348ENST000003994102311112_1132117.01532.0TransmembraneNote=Helical%3B Name%3D15
TgeneABCC1chr12:68707223chr16:16108348ENST000003994102311204_1224117.01532.0TransmembraneNote=Helical%3B Name%3D16
TgeneABCC1chr12:68707223chr16:16108348ENST000003994102311227_1247117.01532.0TransmembraneNote=Helical%3B Name%3D17
TgeneABCC1chr12:68707223chr16:16108348ENST00000399410231134_154117.01532.0TransmembraneNote=Helical%3B Name%3D4
TgeneABCC1chr12:68707223chr16:16108348ENST00000399410231173_193117.01532.0TransmembraneNote=Helical%3B Name%3D5
TgeneABCC1chr12:68707223chr16:16108348ENST00000399410231317_337117.01532.0TransmembraneNote=Helical%3B Name%3D6
TgeneABCC1chr12:68707223chr16:16108348ENST00000399410231364_384117.01532.0TransmembraneNote=Helical%3B Name%3D7
TgeneABCC1chr12:68707223chr16:16108348ENST00000399410231441_461117.01532.0TransmembraneNote=Helical%3B Name%3D8
TgeneABCC1chr12:68707223chr16:16108348ENST00000399410231465_485117.01532.0TransmembraneNote=Helical%3B Name%3D9
TgeneABCC1chr12:68707223chr16:16108348ENST00000399410231548_568117.01532.0TransmembraneNote=Helical%3B Name%3D10
TgeneABCC1chr12:68707223chr16:16108348ENST00000399410231591_611117.01532.0TransmembraneNote=Helical%3B Name%3D11
TgeneABCC1chr12:68707223chr16:16108348ENST00000399410231968_988117.01532.0TransmembraneNote=Helical%3B Name%3D12

- Not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneABCC1chr12:68707223chr16:16108348ENST000003451482301_33117.01467.0Topological domainNote=Extracellular
TgeneABCC1chr12:68707223chr16:16108348ENST0000034514823055_74117.01467.0Topological domainNote=Cytoplasmic
TgeneABCC1chr12:68707223chr16:16108348ENST0000034514823096_100117.01467.0Topological domainNote=Extracellular
TgeneABCC1chr12:68707223chr16:16108348ENST000003463702301_33117.01476.0Topological domainNote=Extracellular
TgeneABCC1chr12:68707223chr16:16108348ENST0000034637023055_74117.01476.0Topological domainNote=Cytoplasmic
TgeneABCC1chr12:68707223chr16:16108348ENST0000034637023096_100117.01476.0Topological domainNote=Extracellular
TgeneABCC1chr12:68707223chr16:16108348ENST000003490292291_33117.01417.0Topological domainNote=Extracellular
TgeneABCC1chr12:68707223chr16:16108348ENST0000034902922955_74117.01417.0Topological domainNote=Cytoplasmic
TgeneABCC1chr12:68707223chr16:16108348ENST0000034902922996_100117.01417.0Topological domainNote=Extracellular
TgeneABCC1chr12:68707223chr16:16108348ENST000003511542301_33117.01473.0Topological domainNote=Extracellular
TgeneABCC1chr12:68707223chr16:16108348ENST0000035115423055_74117.01473.0Topological domainNote=Cytoplasmic
TgeneABCC1chr12:68707223chr16:16108348ENST0000035115423096_100117.01473.0Topological domainNote=Extracellular
TgeneABCC1chr12:68707223chr16:16108348ENST000003994082321_33117.01542.0Topological domainNote=Extracellular
TgeneABCC1chr12:68707223chr16:16108348ENST0000039940823255_74117.01542.0Topological domainNote=Cytoplasmic
TgeneABCC1chr12:68707223chr16:16108348ENST0000039940823296_100117.01542.0Topological domainNote=Extracellular
TgeneABCC1chr12:68707223chr16:16108348ENST000003994102311_33117.01532.0Topological domainNote=Extracellular
TgeneABCC1chr12:68707223chr16:16108348ENST0000039941023155_74117.01532.0Topological domainNote=Cytoplasmic
TgeneABCC1chr12:68707223chr16:16108348ENST0000039941023196_100117.01532.0Topological domainNote=Extracellular
TgeneABCC1chr12:68707223chr16:16108348ENST00000345148230101_121117.01467.0TransmembraneNote=Helical%3B Name%3D3
TgeneABCC1chr12:68707223chr16:16108348ENST0000034514823034_54117.01467.0TransmembraneNote=Helical%3B Name%3D1
TgeneABCC1chr12:68707223chr16:16108348ENST0000034514823075_95117.01467.0TransmembraneNote=Helical%3B Name%3D2
TgeneABCC1chr12:68707223chr16:16108348ENST00000346370230101_121117.01476.0TransmembraneNote=Helical%3B Name%3D3
TgeneABCC1chr12:68707223chr16:16108348ENST0000034637023034_54117.01476.0TransmembraneNote=Helical%3B Name%3D1
TgeneABCC1chr12:68707223chr16:16108348ENST0000034637023075_95117.01476.0TransmembraneNote=Helical%3B Name%3D2
TgeneABCC1chr12:68707223chr16:16108348ENST00000349029229101_121117.01417.0TransmembraneNote=Helical%3B Name%3D3
TgeneABCC1chr12:68707223chr16:16108348ENST0000034902922934_54117.01417.0TransmembraneNote=Helical%3B Name%3D1
TgeneABCC1chr12:68707223chr16:16108348ENST0000034902922975_95117.01417.0TransmembraneNote=Helical%3B Name%3D2
TgeneABCC1chr12:68707223chr16:16108348ENST00000351154230101_121117.01473.0TransmembraneNote=Helical%3B Name%3D3
TgeneABCC1chr12:68707223chr16:16108348ENST0000035115423034_54117.01473.0TransmembraneNote=Helical%3B Name%3D1
TgeneABCC1chr12:68707223chr16:16108348ENST0000035115423075_95117.01473.0TransmembraneNote=Helical%3B Name%3D2
TgeneABCC1chr12:68707223chr16:16108348ENST00000399408232101_121117.01542.0TransmembraneNote=Helical%3B Name%3D3
TgeneABCC1chr12:68707223chr16:16108348ENST0000039940823234_54117.01542.0TransmembraneNote=Helical%3B Name%3D1
TgeneABCC1chr12:68707223chr16:16108348ENST0000039940823275_95117.01542.0TransmembraneNote=Helical%3B Name%3D2
TgeneABCC1chr12:68707223chr16:16108348ENST00000399410231101_121117.01532.0TransmembraneNote=Helical%3B Name%3D3
TgeneABCC1chr12:68707223chr16:16108348ENST0000039941023134_54117.01532.0TransmembraneNote=Helical%3B Name%3D1
TgeneABCC1chr12:68707223chr16:16108348ENST0000039941023175_95117.01532.0TransmembraneNote=Helical%3B Name%3D2


Top

Fusion Protein-Protein Interaction


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type from validated records (BIOGRID-3.4.160)
GenePPI interactors


check button Protein-protein interactors based on sequence similarity (STRING)
GeneSTRING network
MDM1
ABCC1


check button - Retained interactions in fusion protein (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost interactions due to fusion (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs to MDM1-ABCC1


check button Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDrugSourcePMID

Top

Related Diseases to MDM1-ABCC1


check button Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDiseaseSourcePMID

check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource