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Center for Computational Systems Medicine level1
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Fusion Gene Summary

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Fusion Gene Sample Information

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Fusion ORF Analysis

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Fusion Amino Acid Sequences

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Fusion Protein Functional Features

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Fusion Protein-Protein Interaction

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Related drugs with this fusion protein

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Related disease with this fusion protein

Fusion Protein:MEN1-PTPRJ

Fusion Protein Summary

check button Fusion gene summary
Fusion partner gene informationFusion gene name: MEN1-PTPRJ
FusionPDB ID: 52984
FusionGDB2.0 ID: 52984
HgeneTgene
Gene symbol

MEN1

PTPRJ

Gene ID

4221

5795

Gene namemenin 1protein tyrosine phosphatase receptor type J
SynonymsMEAI|SCG2CD148|DEP1|HPTPeta|R-PTP-ETA|SCC1
Cytomap

11q13.1

11p11.2

Type of geneprotein-codingprotein-coding
Descriptionmeninreceptor-type tyrosine-protein phosphatase etaCD148 antigenDEP-1HPTP etaR-PTP-Jdensity-enhanced phosphatase 1human density enhanced phosphatase-1protein tyrosine phosphatase, receptor type, J polypeptideprotein-tyrosine phosphatase etasusceptibil
Modification date2020032020200313
UniProtAcc

O00255

.
Ensembl transtripts involved in fusion geneENST idsENST00000312049, ENST00000315422, 
ENST00000377316, ENST00000377321, 
ENST00000377326, ENST00000337652, 
ENST00000377313, ENST00000394374, 
ENST00000394376, ENST00000443283, 
ENST00000478548, 		ENST00000526550, 
ENST00000418331, ENST00000440289, 
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)* DoF score3 X 3 X 3=275 X 6 X 3=90
# samples 36
** MAII scorelog2(3/27*10)=0.15200309344505
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(6/90*10)=-0.584962500721156
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context (manual curation of fusion genes in FusionPDB)

PubMed: MEN1 [Title/Abstract] AND PTPRJ [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)MEN1(64577137)-PTPRJ(48149332), # samples:3
Anticipated loss of major functional domain due to fusion event.MEN1-PTPRJ seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
MEN1-PTPRJ seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
MEN1-PTPRJ seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
MEN1-PTPRJ seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
MEN1-PTPRJ seems lost the major protein functional domain in Hgene partner, which is a CGC due to the frame-shifted ORF.
MEN1-PTPRJ seems lost the major protein functional domain in Hgene partner, which is a epigenetic factor due to the frame-shifted ORF.
MEN1-PTPRJ seems lost the major protein functional domain in Hgene partner, which is a tumor suppressor due to the frame-shifted ORF.
MEN1-PTPRJ seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
MEN1-PTPRJ seems lost the major protein functional domain in Tgene partner, which is a tumor suppressor due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneMEN1

GO:0000122

negative regulation of transcription by RNA polymerase II

9989505|12837246|23784080

HgeneMEN1

GO:0000165

MAPK cascade

12226747

HgeneMEN1

GO:0001933

negative regulation of protein phosphorylation

12226747

HgeneMEN1

GO:0006974

cellular response to DNA damage stimulus

16690369

HgeneMEN1

GO:0008285

negative regulation of cell proliferation

15331604

HgeneMEN1

GO:0009411

response to UV

16690369

HgeneMEN1

GO:0010332

response to gamma radiation

12874027

HgeneMEN1

GO:0032092

positive regulation of protein binding

20484083

HgeneMEN1

GO:0043433

negative regulation of DNA-binding transcription factor activity

11526476|12226747

HgeneMEN1

GO:0045786

negative regulation of cell cycle

15331604

HgeneMEN1

GO:0045892

negative regulation of transcription, DNA-templated

12226747

HgeneMEN1

GO:0046329

negative regulation of JNK cascade

12226747

TgenePTPRJ

GO:0008285

negative regulation of cell proliferation

14709717|16682945

TgenePTPRJ

GO:0010642

negative regulation of platelet-derived growth factor receptor signaling pathway

14709717

TgenePTPRJ

GO:0030308

negative regulation of cell growth

14709717

TgenePTPRJ

GO:0030336

negative regulation of cell migration

16682945

TgenePTPRJ

GO:0035335

peptidyl-tyrosine dephosphorylation

9531590|10821867|12913111|18348712|18936167|19332538

TgenePTPRJ

GO:0043116

negative regulation of vascular permeability

19332538

TgenePTPRJ

GO:0043407

negative regulation of MAP kinase activity

19494114

TgenePTPRJ

GO:0050860

negative regulation of T cell receptor signaling pathway

12913111

TgenePTPRJ

GO:0050918

positive chemotaxis

14709717


check buttonFusion gene breakpoints across MEN1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across PTPRJ (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure


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Fusion Gene Sample Information

check buttonFusion gene information from FusionGDB2.0.
check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4CESCTCGA-C5-A3HD-01BMEN1chr11

64577137

-PTPRJchr11

48149332

+


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Fusion ORF Analysis


check buttonFusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000377321MEN1chr1164577137-ENST00000418331PTPRJchr1148149332+41905136834331121
ENST00000377321MEN1chr1164577137-ENST00000440289PTPRJchr1148149332+2245513681039323
ENST00000315422MEN1chr1164577137-ENST00000418331PTPRJchr1148149332+461994226038621200
ENST00000315422MEN1chr1164577137-ENST00000440289PTPRJchr1148149332+26749422601468402

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000377321ENST00000418331MEN1chr1164577137-PTPRJchr1148149332+0.0002806370.9997193
ENST00000377321ENST00000440289MEN1chr1164577137-PTPRJchr1148149332+0.0002923250.99970764
ENST00000315422ENST00000418331MEN1chr1164577137-PTPRJchr1148149332+0.0004172330.9995828
ENST00000315422ENST00000440289MEN1chr1164577137-PTPRJchr1148149332+0.0003661810.9996338

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Fusion Amino Acid Sequences


check button For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

>52984_52984_1_MEN1-PTPRJ_MEN1_chr11_64577137_ENST00000315422_PTPRJ_chr11_48149332_ENST00000418331_length(amino acids)=1200AA_BP=226
MGFGGLTWVRFLDRLYSPGGTVVERGRGGHWGSSLGCLGRTPSGTGRPGIVGDKKALQSRLRGLTDKRGEAGRRPPPAAMGLKAAQKTLF
PLRSIDDVVRLFAAELGREEPDLVLLSLVLGFVEHFLAVNRVIPTNVPELTFQPSPAPDPPGGLTYFPVADLSIIAALYARFTAQIRGAV
DLSLYPREGGVSSRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSFITDAIQVFDVTAVNISATSLTLIWKVSDNESSSNYTYKIHVAGET
DSSNLNVSEPRAVIPGLRSSTFYNITVCPVLGDIEGTPGFLQVHTPPVPVSDFRVTVVSTTEIGLAWSSHDAESFQMHITQEGAGNSRVE
ITTNQSIIIGGLFPGTKYCFEIVPKGPNGTEGASRTVCNRTVPSAVFDIHVVYVTTTEMWLDWKSPDGASEYVYHLVIESKHGSNHTSTY
DKAITLQGLIPGTLYNITISPEVDHVWGDPNSTAQYTRPSNVSNIDVSTNTTAATLSWQNFDDASPTYSYCLLIEKAGNSSNATQVVTDI
GITDATVTELIPGSSYTVEIFAQVGDGIKSLEPGRKSFCTDPASMASFDCEVVPKEPALVLKWTCPPGANAGFELEVSSGAWNNATHLES
CSSENGTEYRTEVTYLNFSTSYNISITTVSCGKMAAPTRNTCTTGITDPPPPDGSPNITSVSHNSVKVKFSGFEASHGPIKAYAVILTTG
EAGHPSADVLKYTYEDFKKGASDTYVTYLIRTEEKGRSQSLSEVLKYEIDVGNESTTLGYYNGKLEPLGSYRACVAGFTNITFHPQNKGL
IDGAESYVSFSRYSDAVSLPQDPGVICGAVFGCIFGALVIVTVGGFIFWRKKRKDAKNNEVSFSQIKPKKSKLIRVENFEAYFKKQQADS
NCGFAEEYEDLKLVGISQPKYAAELAENRGKNRYNNVLPYDISRVKLSVQTHSTDDYINANYMPGYHSKKDFIATQGPLPNTLKDFWRMV
WEKNVYAIIMLTKCVEQGRTKCEEYWPSKQAQDYGDITVAMTSEIVLPEWTIRDFTVKNIQTSESHPLRQFHFTSWPDHGVPDTTDLLIN
FRYLVRDYMKQSPPESPILVHCSAGVGRTGTFIAIDRLIYQIENENTVDVYGIVYDLRMHRPLMVQTEDQYVFLNQCVLDIVRSQKDSKV

--------------------------------------------------------------

>52984_52984_2_MEN1-PTPRJ_MEN1_chr11_64577137_ENST00000315422_PTPRJ_chr11_48149332_ENST00000440289_length(amino acids)=402AA_BP=226
MGFGGLTWVRFLDRLYSPGGTVVERGRGGHWGSSLGCLGRTPSGTGRPGIVGDKKALQSRLRGLTDKRGEAGRRPPPAAMGLKAAQKTLF
PLRSIDDVVRLFAAELGREEPDLVLLSLVLGFVEHFLAVNRVIPTNVPELTFQPSPAPDPPGGLTYFPVADLSIIAALYARFTAQIRGAV
DLSLYPREGGVSSRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSFITDAIQVFDVTAVNISATSLTLIWKVSDNESSSNYTYKIHVAGET
DSSNLNVSEPRAVIPGLRSSTFYNITVCPVLGDIEGTPGFLQVHTPPVPVSDFRVTVVSTTEIGLAWSSHDAESFQMHITQEGAGNSRVE

--------------------------------------------------------------

>52984_52984_3_MEN1-PTPRJ_MEN1_chr11_64577137_ENST00000377321_PTPRJ_chr11_48149332_ENST00000418331_length(amino acids)=1121AA_BP=147
MGLKAAQKTLFPLRSIDDVVRLFAAELGREEPDLVLLSLVLGFVEHFLAVNRVIPTNVPELTFQPSPAPDPPGGLTYFPVADLSIIAALY
ARFTAQIRGAVDLSLYPREGGVSSRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSFITDAIQVFDVTAVNISATSLTLIWKVSDNESSSN
YTYKIHVAGETDSSNLNVSEPRAVIPGLRSSTFYNITVCPVLGDIEGTPGFLQVHTPPVPVSDFRVTVVSTTEIGLAWSSHDAESFQMHI
TQEGAGNSRVEITTNQSIIIGGLFPGTKYCFEIVPKGPNGTEGASRTVCNRTVPSAVFDIHVVYVTTTEMWLDWKSPDGASEYVYHLVIE
SKHGSNHTSTYDKAITLQGLIPGTLYNITISPEVDHVWGDPNSTAQYTRPSNVSNIDVSTNTTAATLSWQNFDDASPTYSYCLLIEKAGN
SSNATQVVTDIGITDATVTELIPGSSYTVEIFAQVGDGIKSLEPGRKSFCTDPASMASFDCEVVPKEPALVLKWTCPPGANAGFELEVSS
GAWNNATHLESCSSENGTEYRTEVTYLNFSTSYNISITTVSCGKMAAPTRNTCTTGITDPPPPDGSPNITSVSHNSVKVKFSGFEASHGP
IKAYAVILTTGEAGHPSADVLKYTYEDFKKGASDTYVTYLIRTEEKGRSQSLSEVLKYEIDVGNESTTLGYYNGKLEPLGSYRACVAGFT
NITFHPQNKGLIDGAESYVSFSRYSDAVSLPQDPGVICGAVFGCIFGALVIVTVGGFIFWRKKRKDAKNNEVSFSQIKPKKSKLIRVENF
EAYFKKQQADSNCGFAEEYEDLKLVGISQPKYAAELAENRGKNRYNNVLPYDISRVKLSVQTHSTDDYINANYMPGYHSKKDFIATQGPL
PNTLKDFWRMVWEKNVYAIIMLTKCVEQGRTKCEEYWPSKQAQDYGDITVAMTSEIVLPEWTIRDFTVKNIQTSESHPLRQFHFTSWPDH
GVPDTTDLLINFRYLVRDYMKQSPPESPILVHCSAGVGRTGTFIAIDRLIYQIENENTVDVYGIVYDLRMHRPLMVQTEDQYVFLNQCVL

--------------------------------------------------------------

>52984_52984_4_MEN1-PTPRJ_MEN1_chr11_64577137_ENST00000377321_PTPRJ_chr11_48149332_ENST00000440289_length(amino acids)=323AA_BP=147
MGLKAAQKTLFPLRSIDDVVRLFAAELGREEPDLVLLSLVLGFVEHFLAVNRVIPTNVPELTFQPSPAPDPPGGLTYFPVADLSIIAALY
ARFTAQIRGAVDLSLYPREGGVSSRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSFITDAIQVFDVTAVNISATSLTLIWKVSDNESSSN
YTYKIHVAGETDSSNLNVSEPRAVIPGLRSSTFYNITVCPVLGDIEGTPGFLQVHTPPVPVSDFRVTVVSTTEIGLAWSSHDAESFQMHI

--------------------------------------------------------------

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Fusion Protein Functional Features


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr11:64577137/chr11:48149332)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
MEN1

O00255

.
FUNCTION: Essential component of a MLL/SET1 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3 (H3K4). Functions as a transcriptional regulator. Binds to the TERT promoter and represses telomerase expression. Plays a role in TGFB1-mediated inhibition of cell-proliferation, possibly regulating SMAD3 transcriptional activity. Represses JUND-mediated transcriptional activation on AP1 sites, as well as that mediated by NFKB subunit RELA. Positively regulates HOXC8 and HOXC6 gene expression. May be involved in normal hematopoiesis through the activation of HOXA9 expression (By similarity). May be involved in DNA repair. {ECO:0000250|UniProtKB:O88559, ECO:0000269|PubMed:11274402, ECO:0000269|PubMed:11526476, ECO:0000269|PubMed:12837246, ECO:0000269|PubMed:12874027, ECO:0000269|PubMed:14992727, ECO:0000269|PubMed:22327296}.FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

* Minus value of BPloci means that the break pointn is located before the CDS.
- Retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgenePTPRJchr11:64577137chr11:48149332ENST000004183315251041_1298364.33333333333331338.0DomainTyrosine-protein phosphatase
TgenePTPRJchr11:64577137chr11:48149332ENST00000418331525368_456364.33333333333331338.0DomainFibronectin type-III 4
TgenePTPRJchr11:64577137chr11:48149332ENST00000418331525457_541364.33333333333331338.0DomainFibronectin type-III 5
TgenePTPRJchr11:64577137chr11:48149332ENST00000418331525542_623364.33333333333331338.0DomainFibronectin type-III 6
TgenePTPRJchr11:64577137chr11:48149332ENST00000418331525625_720364.33333333333331338.0DomainFibronectin type-III 7
TgenePTPRJchr11:64577137chr11:48149332ENST00000418331525721_817364.33333333333331338.0DomainFibronectin type-III 8
TgenePTPRJchr11:64577137chr11:48149332ENST00000418331525816_902364.33333333333331338.0DomainFibronectin type-III 9
TgenePTPRJchr11:64577137chr11:48149332ENST00000440289591041_1298364.3333333333333540.0DomainTyrosine-protein phosphatase
TgenePTPRJchr11:64577137chr11:48149332ENST0000044028959368_456364.3333333333333540.0DomainFibronectin type-III 4
TgenePTPRJchr11:64577137chr11:48149332ENST0000044028959457_541364.3333333333333540.0DomainFibronectin type-III 5
TgenePTPRJchr11:64577137chr11:48149332ENST0000044028959542_623364.3333333333333540.0DomainFibronectin type-III 6
TgenePTPRJchr11:64577137chr11:48149332ENST0000044028959625_720364.3333333333333540.0DomainFibronectin type-III 7
TgenePTPRJchr11:64577137chr11:48149332ENST0000044028959721_817364.3333333333333540.0DomainFibronectin type-III 8
TgenePTPRJchr11:64577137chr11:48149332ENST0000044028959816_902364.3333333333333540.0DomainFibronectin type-III 9
TgenePTPRJchr11:64577137chr11:48149332ENST000004183315251239_1245364.33333333333331338.0RegionSubstrate binding
TgenePTPRJchr11:64577137chr11:48149332ENST00000440289591239_1245364.3333333333333540.0RegionSubstrate binding
TgenePTPRJchr11:64577137chr11:48149332ENST00000418331525997_1337364.33333333333331338.0Topological domainCytoplasmic
TgenePTPRJchr11:64577137chr11:48149332ENST0000044028959997_1337364.3333333333333540.0Topological domainCytoplasmic
TgenePTPRJchr11:64577137chr11:48149332ENST00000418331525976_996364.33333333333331338.0TransmembraneHelical
TgenePTPRJchr11:64577137chr11:48149332ENST0000044028959976_996364.3333333333333540.0TransmembraneHelical

- Not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgenePTPRJchr11:64577137chr11:48149332ENST00000418331525121_209364.33333333333331338.0DomainFibronectin type-III 1
TgenePTPRJchr11:64577137chr11:48149332ENST00000418331525207_291364.33333333333331338.0DomainFibronectin type-III 2
TgenePTPRJchr11:64577137chr11:48149332ENST00000418331525271_364364.33333333333331338.0DomainFibronectin type-III 3
TgenePTPRJchr11:64577137chr11:48149332ENST0000044028959121_209364.3333333333333540.0DomainFibronectin type-III 1
TgenePTPRJchr11:64577137chr11:48149332ENST0000044028959207_291364.3333333333333540.0DomainFibronectin type-III 2
TgenePTPRJchr11:64577137chr11:48149332ENST0000044028959271_364364.3333333333333540.0DomainFibronectin type-III 3
TgenePTPRJchr11:64577137chr11:48149332ENST0000041833152536_975364.33333333333331338.0Topological domainExtracellular
TgenePTPRJchr11:64577137chr11:48149332ENST000004402895936_975364.3333333333333540.0Topological domainExtracellular


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Fusion Protein-Protein Interaction


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type from validated records (BIOGRID-3.4.160)
GenePPI interactors


check button Protein-protein interactors based on sequence similarity (STRING)
GeneSTRING network
MEN1
PTPRJ


check button - Retained interactions in fusion protein (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost interactions due to fusion (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneMEN1chr11:64577137chr11:48149332ENST00000312049-210219_395148.33333333333334611.0FANCD2
HgeneMEN1chr11:64577137chr11:48149332ENST00000315422-210219_395148.33333333333334611.0FANCD2
HgeneMEN1chr11:64577137chr11:48149332ENST00000337652-110219_3950616.0FANCD2
HgeneMEN1chr11:64577137chr11:48149332ENST00000377313-19219_3950616.0FANCD2
HgeneMEN1chr11:64577137chr11:48149332ENST00000377321-210219_395148.33333333333334576.0FANCD2
HgeneMEN1chr11:64577137chr11:48149332ENST00000377326-19219_395148.33333333333334611.0FANCD2
HgeneMEN1chr11:64577137chr11:48149332ENST00000394374-110219_3950616.0FANCD2
HgeneMEN1chr11:64577137chr11:48149332ENST00000394376-111219_3950616.0FANCD2
HgeneMEN1chr11:64577137chr11:48149332ENST00000443283-110219_3950616.0FANCD2


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Related Drugs to MEN1-PTPRJ


check button Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDrugSourcePMID

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Related Diseases to MEN1-PTPRJ


check button Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDiseaseSourcePMID

check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource