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Fusion Protein:ARAP1-IL12RB2 |
Fusion Protein Summary |
 Fusion gene summary |
| Fusion partner gene information | Fusion gene name: ARAP1-IL12RB2 | FusionPDB ID: 5760 | FusionGDB2.0 ID: 5760 | Hgene | Tgene | Gene symbol | ARAP1 | IL12RB2 | Gene ID | 116985 | 3595 |
| Gene name | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 | interleukin 12 receptor subunit beta 2 | |
| Synonyms | CENTD2 | - | |
| Cytomap | 11q13.4 | 1p31.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1ARF-GAP, RHO-GAP, ankyrin repeat, and pleckstrin homology domains-containing protein 1centaurin-delta-2cnt-d2 | interleukin-12 receptor subunit beta-2IL-12 receptor subunit beta-2IL-12R subunit beta-2interleukin 12 receptor, beta 2interleukin-12 receptor beta-2 chain | |
| Modification date | 20200313 | 20200315 | |
| UniProtAcc | Q96P48 | Q99665 | |
| Ensembl transtripts involved in fusion gene | ENST ids | ENST00000334211, ENST00000359373, ENST00000393605, ENST00000393609, ENST00000426523, ENST00000429686, ENST00000455638, ENST00000495878, | ENST00000465396, ENST00000262345, ENST00000371000, ENST00000541374, ENST00000544434, |
| Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0) | * DoF score | 15 X 15 X 9=2025 | 3 X 4 X 3=36 |
| # samples | 17 | 4 | |
| ** MAII score | log2(17/2025*10)=-3.57431525652165 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(4/36*10)=0.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context (manual curation of fusion genes in FusionPDB) | PubMed: ARAP1 [Title/Abstract] AND IL12RB2 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0) | ARAP1(72404370)-IL12RB2(67816553), # samples:2 ARAP1(72404369)-IL12RB2(67816552), # samples:2 | ||
| Anticipated loss of major functional domain due to fusion event. | ARAP1-IL12RB2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. ARAP1-IL12RB2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. ARAP1-IL12RB2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. ARAP1-IL12RB2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. ARAP1-IL12RB2 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF. ARAP1-IL12RB2 seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | ARAP1 | GO:0043547 | positive regulation of GTPase activity | 11804590 |
| Tgene | IL12RB2 | GO:0032729 | positive regulation of interferon-gamma production | 11114383 |
| Fusion gene breakpoints across ARAP1 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across IL12RB2 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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Fusion Gene Sample Information |
| Fusion gene information from FusionGDB2.0. |
| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | ESCA | TCGA-L5-A8NS-01A | ARAP1 | chr11 | 72404370 | - | IL12RB2 | chr1 | 67816553 | + |
| ChimerDB4 | ESCA | TCGA-L5-A8NS | ARAP1 | chr11 | 72404369 | - | IL12RB2 | chr1 | 67816552 | + |
| ChimerDB4 | ESCA | TCGA-L5-A8NS | ARAP1 | chr11 | 72404370 | - | IL12RB2 | chr1 | 67816553 | + |
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Fusion ORF Analysis |
| Fusion information from ORFfinder translation from full-length transcript sequence from FusionPDB. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000359373 | ARAP1 | chr11 | 72404370 | - | ENST00000371000 | IL12RB2 | chr1 | 67816553 | + | 7068 | 4806 | 810 | 5747 | 1645 |
| ENST00000359373 | ARAP1 | chr11 | 72404370 | - | ENST00000262345 | IL12RB2 | chr1 | 67816553 | + | 7168 | 4806 | 810 | 6356 | 1848 |
| ENST00000359373 | ARAP1 | chr11 | 72404370 | - | ENST00000541374 | IL12RB2 | chr1 | 67816553 | + | 6003 | 4806 | 810 | 5747 | 1645 |
| ENST00000359373 | ARAP1 | chr11 | 72404370 | - | ENST00000544434 | IL12RB2 | chr1 | 67816553 | + | 6157 | 4806 | 810 | 6098 | 1762 |
| ENST00000455638 | ARAP1 | chr11 | 72404370 | - | ENST00000371000 | IL12RB2 | chr1 | 67816553 | + | 6216 | 3954 | 0 | 4895 | 1631 |
| ENST00000455638 | ARAP1 | chr11 | 72404370 | - | ENST00000262345 | IL12RB2 | chr1 | 67816553 | + | 6316 | 3954 | 0 | 5504 | 1834 |
| ENST00000455638 | ARAP1 | chr11 | 72404370 | - | ENST00000541374 | IL12RB2 | chr1 | 67816553 | + | 5151 | 3954 | 0 | 4895 | 1631 |
| ENST00000455638 | ARAP1 | chr11 | 72404370 | - | ENST00000544434 | IL12RB2 | chr1 | 67816553 | + | 5305 | 3954 | 0 | 5246 | 1748 |
| ENST00000393605 | ARAP1 | chr11 | 72404370 | - | ENST00000371000 | IL12RB2 | chr1 | 67816553 | + | 6052 | 3790 | 544 | 4731 | 1395 |
| ENST00000393605 | ARAP1 | chr11 | 72404370 | - | ENST00000262345 | IL12RB2 | chr1 | 67816553 | + | 6152 | 3790 | 544 | 5340 | 1598 |
| ENST00000393605 | ARAP1 | chr11 | 72404370 | - | ENST00000541374 | IL12RB2 | chr1 | 67816553 | + | 4987 | 3790 | 544 | 4731 | 1395 |
| ENST00000393605 | ARAP1 | chr11 | 72404370 | - | ENST00000544434 | IL12RB2 | chr1 | 67816553 | + | 5141 | 3790 | 544 | 5082 | 1512 |
| ENST00000334211 | ARAP1 | chr11 | 72404370 | - | ENST00000371000 | IL12RB2 | chr1 | 67816553 | + | 6216 | 3954 | 510 | 4895 | 1461 |
| ENST00000334211 | ARAP1 | chr11 | 72404370 | - | ENST00000262345 | IL12RB2 | chr1 | 67816553 | + | 6316 | 3954 | 510 | 5504 | 1664 |
| ENST00000334211 | ARAP1 | chr11 | 72404370 | - | ENST00000541374 | IL12RB2 | chr1 | 67816553 | + | 5151 | 3954 | 510 | 4895 | 1461 |
| ENST00000334211 | ARAP1 | chr11 | 72404370 | - | ENST00000544434 | IL12RB2 | chr1 | 67816553 | + | 5305 | 3954 | 510 | 5246 | 1578 |
| ENST00000426523 | ARAP1 | chr11 | 72404370 | - | ENST00000371000 | IL12RB2 | chr1 | 67816553 | + | 5886 | 3624 | 180 | 4565 | 1461 |
| ENST00000426523 | ARAP1 | chr11 | 72404370 | - | ENST00000262345 | IL12RB2 | chr1 | 67816553 | + | 5986 | 3624 | 180 | 5174 | 1664 |
| ENST00000426523 | ARAP1 | chr11 | 72404370 | - | ENST00000541374 | IL12RB2 | chr1 | 67816553 | + | 4821 | 3624 | 180 | 4565 | 1461 |
| ENST00000426523 | ARAP1 | chr11 | 72404370 | - | ENST00000544434 | IL12RB2 | chr1 | 67816553 | + | 4975 | 3624 | 180 | 4916 | 1578 |
| ENST00000429686 | ARAP1 | chr11 | 72404370 | - | ENST00000371000 | IL12RB2 | chr1 | 67816553 | + | 5703 | 3441 | 180 | 4382 | 1400 |
| ENST00000429686 | ARAP1 | chr11 | 72404370 | - | ENST00000262345 | IL12RB2 | chr1 | 67816553 | + | 5803 | 3441 | 180 | 4991 | 1603 |
| ENST00000429686 | ARAP1 | chr11 | 72404370 | - | ENST00000541374 | IL12RB2 | chr1 | 67816553 | + | 4638 | 3441 | 180 | 4382 | 1400 |
| ENST00000429686 | ARAP1 | chr11 | 72404370 | - | ENST00000544434 | IL12RB2 | chr1 | 67816553 | + | 4792 | 3441 | 180 | 4733 | 1517 |
| ENST00000359373 | ARAP1 | chr11 | 72404369 | - | ENST00000371000 | IL12RB2 | chr1 | 67816552 | + | 7068 | 4806 | 810 | 5747 | 1645 |
| ENST00000359373 | ARAP1 | chr11 | 72404369 | - | ENST00000262345 | IL12RB2 | chr1 | 67816552 | + | 7168 | 4806 | 810 | 6356 | 1848 |
| ENST00000359373 | ARAP1 | chr11 | 72404369 | - | ENST00000541374 | IL12RB2 | chr1 | 67816552 | + | 6003 | 4806 | 810 | 5747 | 1645 |
| ENST00000359373 | ARAP1 | chr11 | 72404369 | - | ENST00000544434 | IL12RB2 | chr1 | 67816552 | + | 6157 | 4806 | 810 | 6098 | 1762 |
| ENST00000455638 | ARAP1 | chr11 | 72404369 | - | ENST00000371000 | IL12RB2 | chr1 | 67816552 | + | 6216 | 3954 | 0 | 4895 | 1631 |
| ENST00000455638 | ARAP1 | chr11 | 72404369 | - | ENST00000262345 | IL12RB2 | chr1 | 67816552 | + | 6316 | 3954 | 0 | 5504 | 1834 |
| ENST00000455638 | ARAP1 | chr11 | 72404369 | - | ENST00000541374 | IL12RB2 | chr1 | 67816552 | + | 5151 | 3954 | 0 | 4895 | 1631 |
| ENST00000455638 | ARAP1 | chr11 | 72404369 | - | ENST00000544434 | IL12RB2 | chr1 | 67816552 | + | 5305 | 3954 | 0 | 5246 | 1748 |
| ENST00000393605 | ARAP1 | chr11 | 72404369 | - | ENST00000371000 | IL12RB2 | chr1 | 67816552 | + | 6052 | 3790 | 544 | 4731 | 1395 |
| ENST00000393605 | ARAP1 | chr11 | 72404369 | - | ENST00000262345 | IL12RB2 | chr1 | 67816552 | + | 6152 | 3790 | 544 | 5340 | 1598 |
| ENST00000393605 | ARAP1 | chr11 | 72404369 | - | ENST00000541374 | IL12RB2 | chr1 | 67816552 | + | 4987 | 3790 | 544 | 4731 | 1395 |
| ENST00000393605 | ARAP1 | chr11 | 72404369 | - | ENST00000544434 | IL12RB2 | chr1 | 67816552 | + | 5141 | 3790 | 544 | 5082 | 1512 |
| ENST00000334211 | ARAP1 | chr11 | 72404369 | - | ENST00000371000 | IL12RB2 | chr1 | 67816552 | + | 6216 | 3954 | 510 | 4895 | 1461 |
| ENST00000334211 | ARAP1 | chr11 | 72404369 | - | ENST00000262345 | IL12RB2 | chr1 | 67816552 | + | 6316 | 3954 | 510 | 5504 | 1664 |
| ENST00000334211 | ARAP1 | chr11 | 72404369 | - | ENST00000541374 | IL12RB2 | chr1 | 67816552 | + | 5151 | 3954 | 510 | 4895 | 1461 |
| ENST00000334211 | ARAP1 | chr11 | 72404369 | - | ENST00000544434 | IL12RB2 | chr1 | 67816552 | + | 5305 | 3954 | 510 | 5246 | 1578 |
| ENST00000426523 | ARAP1 | chr11 | 72404369 | - | ENST00000371000 | IL12RB2 | chr1 | 67816552 | + | 5886 | 3624 | 180 | 4565 | 1461 |
| ENST00000426523 | ARAP1 | chr11 | 72404369 | - | ENST00000262345 | IL12RB2 | chr1 | 67816552 | + | 5986 | 3624 | 180 | 5174 | 1664 |
| ENST00000426523 | ARAP1 | chr11 | 72404369 | - | ENST00000541374 | IL12RB2 | chr1 | 67816552 | + | 4821 | 3624 | 180 | 4565 | 1461 |
| ENST00000426523 | ARAP1 | chr11 | 72404369 | - | ENST00000544434 | IL12RB2 | chr1 | 67816552 | + | 4975 | 3624 | 180 | 4916 | 1578 |
| ENST00000429686 | ARAP1 | chr11 | 72404369 | - | ENST00000371000 | IL12RB2 | chr1 | 67816552 | + | 5703 | 3441 | 180 | 4382 | 1400 |
| ENST00000429686 | ARAP1 | chr11 | 72404369 | - | ENST00000262345 | IL12RB2 | chr1 | 67816552 | + | 5803 | 3441 | 180 | 4991 | 1603 |
| ENST00000429686 | ARAP1 | chr11 | 72404369 | - | ENST00000541374 | IL12RB2 | chr1 | 67816552 | + | 4638 | 3441 | 180 | 4382 | 1400 |
| ENST00000429686 | ARAP1 | chr11 | 72404369 | - | ENST00000544434 | IL12RB2 | chr1 | 67816552 | + | 4792 | 3441 | 180 | 4733 | 1517 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000359373 | ENST00000371000 | ARAP1 | chr11 | 72404370 | - | IL12RB2 | chr1 | 67816553 | + | 0.006546251 | 0.99345374 |
| ENST00000359373 | ENST00000262345 | ARAP1 | chr11 | 72404370 | - | IL12RB2 | chr1 | 67816553 | + | 0.005077966 | 0.9949221 |
| ENST00000359373 | ENST00000541374 | ARAP1 | chr11 | 72404370 | - | IL12RB2 | chr1 | 67816553 | + | 0.00831883 | 0.99168116 |
| ENST00000359373 | ENST00000544434 | ARAP1 | chr11 | 72404370 | - | IL12RB2 | chr1 | 67816553 | + | 0.005638213 | 0.99436176 |
| ENST00000455638 | ENST00000371000 | ARAP1 | chr11 | 72404370 | - | IL12RB2 | chr1 | 67816553 | + | 0.003315595 | 0.9966844 |
| ENST00000455638 | ENST00000262345 | ARAP1 | chr11 | 72404370 | - | IL12RB2 | chr1 | 67816553 | + | 0.002569785 | 0.99743026 |
| ENST00000455638 | ENST00000541374 | ARAP1 | chr11 | 72404370 | - | IL12RB2 | chr1 | 67816553 | + | 0.004564666 | 0.9954353 |
| ENST00000455638 | ENST00000544434 | ARAP1 | chr11 | 72404370 | - | IL12RB2 | chr1 | 67816553 | + | 0.003051941 | 0.99694806 |
| ENST00000393605 | ENST00000371000 | ARAP1 | chr11 | 72404370 | - | IL12RB2 | chr1 | 67816553 | + | 0.002614135 | 0.9973859 |
| ENST00000393605 | ENST00000262345 | ARAP1 | chr11 | 72404370 | - | IL12RB2 | chr1 | 67816553 | + | 0.002140866 | 0.9978592 |
| ENST00000393605 | ENST00000541374 | ARAP1 | chr11 | 72404370 | - | IL12RB2 | chr1 | 67816553 | + | 0.003235793 | 0.9967642 |
| ENST00000393605 | ENST00000544434 | ARAP1 | chr11 | 72404370 | - | IL12RB2 | chr1 | 67816553 | + | 0.002202685 | 0.99779737 |
| ENST00000334211 | ENST00000371000 | ARAP1 | chr11 | 72404370 | - | IL12RB2 | chr1 | 67816553 | + | 0.004042203 | 0.9959578 |
| ENST00000334211 | ENST00000262345 | ARAP1 | chr11 | 72404370 | - | IL12RB2 | chr1 | 67816553 | + | 0.003354352 | 0.9966456 |
| ENST00000334211 | ENST00000541374 | ARAP1 | chr11 | 72404370 | - | IL12RB2 | chr1 | 67816553 | + | 0.005109326 | 0.9948907 |
| ENST00000334211 | ENST00000544434 | ARAP1 | chr11 | 72404370 | - | IL12RB2 | chr1 | 67816553 | + | 0.003727505 | 0.99627244 |
| ENST00000426523 | ENST00000371000 | ARAP1 | chr11 | 72404370 | - | IL12RB2 | chr1 | 67816553 | + | 0.003685874 | 0.9963141 |
| ENST00000426523 | ENST00000262345 | ARAP1 | chr11 | 72404370 | - | IL12RB2 | chr1 | 67816553 | + | 0.003052154 | 0.9969478 |
| ENST00000426523 | ENST00000541374 | ARAP1 | chr11 | 72404370 | - | IL12RB2 | chr1 | 67816553 | + | 0.005140742 | 0.9948592 |
| ENST00000426523 | ENST00000544434 | ARAP1 | chr11 | 72404370 | - | IL12RB2 | chr1 | 67816553 | + | 0.003704707 | 0.9962953 |
| ENST00000429686 | ENST00000371000 | ARAP1 | chr11 | 72404370 | - | IL12RB2 | chr1 | 67816553 | + | 0.002913577 | 0.99708647 |
| ENST00000429686 | ENST00000262345 | ARAP1 | chr11 | 72404370 | - | IL12RB2 | chr1 | 67816553 | + | 0.002976318 | 0.99702364 |
| ENST00000429686 | ENST00000541374 | ARAP1 | chr11 | 72404370 | - | IL12RB2 | chr1 | 67816553 | + | 0.004109528 | 0.9958905 |
| ENST00000429686 | ENST00000544434 | ARAP1 | chr11 | 72404370 | - | IL12RB2 | chr1 | 67816553 | + | 0.003611679 | 0.9963883 |
| ENST00000359373 | ENST00000371000 | ARAP1 | chr11 | 72404369 | - | IL12RB2 | chr1 | 67816552 | + | 0.006546251 | 0.99345374 |
| ENST00000359373 | ENST00000262345 | ARAP1 | chr11 | 72404369 | - | IL12RB2 | chr1 | 67816552 | + | 0.005077966 | 0.9949221 |
| ENST00000359373 | ENST00000541374 | ARAP1 | chr11 | 72404369 | - | IL12RB2 | chr1 | 67816552 | + | 0.00831883 | 0.99168116 |
| ENST00000359373 | ENST00000544434 | ARAP1 | chr11 | 72404369 | - | IL12RB2 | chr1 | 67816552 | + | 0.005638213 | 0.99436176 |
| ENST00000455638 | ENST00000371000 | ARAP1 | chr11 | 72404369 | - | IL12RB2 | chr1 | 67816552 | + | 0.003315595 | 0.9966844 |
| ENST00000455638 | ENST00000262345 | ARAP1 | chr11 | 72404369 | - | IL12RB2 | chr1 | 67816552 | + | 0.002569785 | 0.99743026 |
| ENST00000455638 | ENST00000541374 | ARAP1 | chr11 | 72404369 | - | IL12RB2 | chr1 | 67816552 | + | 0.004564666 | 0.9954353 |
| ENST00000455638 | ENST00000544434 | ARAP1 | chr11 | 72404369 | - | IL12RB2 | chr1 | 67816552 | + | 0.003051941 | 0.99694806 |
| ENST00000393605 | ENST00000371000 | ARAP1 | chr11 | 72404369 | - | IL12RB2 | chr1 | 67816552 | + | 0.002614135 | 0.9973859 |
| ENST00000393605 | ENST00000262345 | ARAP1 | chr11 | 72404369 | - | IL12RB2 | chr1 | 67816552 | + | 0.002140866 | 0.9978592 |
| ENST00000393605 | ENST00000541374 | ARAP1 | chr11 | 72404369 | - | IL12RB2 | chr1 | 67816552 | + | 0.003235793 | 0.9967642 |
| ENST00000393605 | ENST00000544434 | ARAP1 | chr11 | 72404369 | - | IL12RB2 | chr1 | 67816552 | + | 0.002202685 | 0.99779737 |
| ENST00000334211 | ENST00000371000 | ARAP1 | chr11 | 72404369 | - | IL12RB2 | chr1 | 67816552 | + | 0.004042203 | 0.9959578 |
| ENST00000334211 | ENST00000262345 | ARAP1 | chr11 | 72404369 | - | IL12RB2 | chr1 | 67816552 | + | 0.003354352 | 0.9966456 |
| ENST00000334211 | ENST00000541374 | ARAP1 | chr11 | 72404369 | - | IL12RB2 | chr1 | 67816552 | + | 0.005109326 | 0.9948907 |
| ENST00000334211 | ENST00000544434 | ARAP1 | chr11 | 72404369 | - | IL12RB2 | chr1 | 67816552 | + | 0.003727505 | 0.99627244 |
| ENST00000426523 | ENST00000371000 | ARAP1 | chr11 | 72404369 | - | IL12RB2 | chr1 | 67816552 | + | 0.003685874 | 0.9963141 |
| ENST00000426523 | ENST00000262345 | ARAP1 | chr11 | 72404369 | - | IL12RB2 | chr1 | 67816552 | + | 0.003052154 | 0.9969478 |
| ENST00000426523 | ENST00000541374 | ARAP1 | chr11 | 72404369 | - | IL12RB2 | chr1 | 67816552 | + | 0.005140742 | 0.9948592 |
| ENST00000426523 | ENST00000544434 | ARAP1 | chr11 | 72404369 | - | IL12RB2 | chr1 | 67816552 | + | 0.003704707 | 0.9962953 |
| ENST00000429686 | ENST00000371000 | ARAP1 | chr11 | 72404369 | - | IL12RB2 | chr1 | 67816552 | + | 0.002913577 | 0.99708647 |
| ENST00000429686 | ENST00000262345 | ARAP1 | chr11 | 72404369 | - | IL12RB2 | chr1 | 67816552 | + | 0.002976318 | 0.99702364 |
| ENST00000429686 | ENST00000541374 | ARAP1 | chr11 | 72404369 | - | IL12RB2 | chr1 | 67816552 | + | 0.004109528 | 0.9958905 |
| ENST00000429686 | ENST00000544434 | ARAP1 | chr11 | 72404369 | - | IL12RB2 | chr1 | 67816552 | + | 0.003611679 | 0.9963883 |
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Fusion Amino Acid Sequences |
| For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP >5760_5760_1_ARAP1-IL12RB2_ARAP1_chr11_72404369_ENST00000334211_IL12RB2_chr1_67816552_ENST00000262345_length(amino acids)=1664AA_BP=1148 MPTKEEESLLPSLSSPPQPQSEEPLSTLPQGPPQPPSPPPCPPEIPPKPVRLFPEFDDSDYDEVPEEGPGAPARVMTKKEEPPPSRVPRA VRVASLLSEGEELSGDDQGDEEEDDHAYEGVPNGGWHTSSLSLSLPSTIAAPHPMDGPPGGSTPVTPVIKAGWLDKNPPQGSYIYQKRWV RLDTDHLRYFDSNKDAYSKRFISVACISHVAAIGDQKFEVITNNRTFAFRAESDVERKEWMQALQQAMAEQRARARLSSAYLLGVPGSEQ PDRAGSLELRGFKNKLYVAVVGDKVQLYKNLEEYHLGIGITFIDMSVGNVKEVDRRSFDLTTPYRIFSFSADSELEKEQWLEAMQGAIAE ALSTSEVAERIWAAAPNRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTETLIELFLQLGNGAGNRFWAAN VPPSEALQPSSSPSTRRCHLEAKYREGKYRRYHPLFGNQEELDKALCAAVTTTDLAETQALLGCGAGINCFSGDPEAPTPLALAEQAGQT LQMEFLRNNRTTEVPRLDSMKPLEKHYSVVLPTVSHSGFLYKTASAGKLLQDRRAREEFSRRWCVLGDGVLSYFENERAVTPNGEIRASE IVCLAVPPPDTHGFEHTFEVYTEGERLYLFGLESAEQAHEWVKCIAKAFVPPLAEDLLARDFERLGRLPYKAGLSLQRAQEGWFSLSGSE LRAVFPEGPCEEPLQLRKLQELSIQGDSENQVLVLVERRRTLYIQGERRLDFMGWLGAIQKAAASMGDTLSEQQLGDSDIPVIVYRCVDY ITQCGLTSEGIYRKCGQTSKTQRLLESLRQDARSVHLKEGEQHVDDVSSALKRFLRDLPDGLFTRAQRLTWLEASEIEDEEEKVSRYREL LVRLPPVNRATVKALISHLYCVQCFSDTNQMNVHNLAIVFGPTLFQTDGQDYKAGRVVEDLINHYVVVFSVDEEELRKQREEITAIVKMR VAGTASGTQHAGDFICTVYLEEKKAETEQHIKVPASMTAEELTLEILDRRNVGIREKDYWTCFEVNEREEAERPLHFAEKVLPILHGLGT DSHLVVKKHQAMEAMLLYLASRVGDTKHGMMKFREDRSLLGLGLPSGGFHDRYFILNSSCLRLYKEVRNLSVSEARGKILHYQVTLQELT GGKAMTQNITGHTSWTTVIPRTGNWAVAVSAANSKGSSLPTRINIMNLCEAGLLAPRQVSANSEGMDNILVTWQPPRKDPSAVQEYVVEW RELHPGGDTQVPLNWLRSRPYNVSALISENIKSYICYEIRVYALSGDQGGCSSILGNSKHKAPLSGPHINAITEEKGSILISWNSIPVQE QMGCLLHYRIYWKERDSNSQPQLCEIPYRVSQNSHPINSLQPRVTYVLWMTALTAAGESSHGNEREFCLQGKANWMAFVAPSICIAIIMV GIFSTHYFQQKVFVLLAALRPQWCSREIPDPANSTCAKKYPIAEEKTQLPLDRLLIDWPTPEDPEPLVISEVLHQVTPVFRHPPCSNWPQ REKGIQGHQASEKDMMHSASSPPPPRALQAESRQLVDLYKVLESRGSDPKPENPACPWTVLPAGDLPTHDGYLPSNIDDLPSHEAPLADS -------------------------------------------------------------- >5760_5760_2_ARAP1-IL12RB2_ARAP1_chr11_72404369_ENST00000334211_IL12RB2_chr1_67816552_ENST00000371000_length(amino acids)=1461AA_BP=1148 MPTKEEESLLPSLSSPPQPQSEEPLSTLPQGPPQPPSPPPCPPEIPPKPVRLFPEFDDSDYDEVPEEGPGAPARVMTKKEEPPPSRVPRA VRVASLLSEGEELSGDDQGDEEEDDHAYEGVPNGGWHTSSLSLSLPSTIAAPHPMDGPPGGSTPVTPVIKAGWLDKNPPQGSYIYQKRWV RLDTDHLRYFDSNKDAYSKRFISVACISHVAAIGDQKFEVITNNRTFAFRAESDVERKEWMQALQQAMAEQRARARLSSAYLLGVPGSEQ PDRAGSLELRGFKNKLYVAVVGDKVQLYKNLEEYHLGIGITFIDMSVGNVKEVDRRSFDLTTPYRIFSFSADSELEKEQWLEAMQGAIAE ALSTSEVAERIWAAAPNRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTETLIELFLQLGNGAGNRFWAAN VPPSEALQPSSSPSTRRCHLEAKYREGKYRRYHPLFGNQEELDKALCAAVTTTDLAETQALLGCGAGINCFSGDPEAPTPLALAEQAGQT LQMEFLRNNRTTEVPRLDSMKPLEKHYSVVLPTVSHSGFLYKTASAGKLLQDRRAREEFSRRWCVLGDGVLSYFENERAVTPNGEIRASE IVCLAVPPPDTHGFEHTFEVYTEGERLYLFGLESAEQAHEWVKCIAKAFVPPLAEDLLARDFERLGRLPYKAGLSLQRAQEGWFSLSGSE LRAVFPEGPCEEPLQLRKLQELSIQGDSENQVLVLVERRRTLYIQGERRLDFMGWLGAIQKAAASMGDTLSEQQLGDSDIPVIVYRCVDY ITQCGLTSEGIYRKCGQTSKTQRLLESLRQDARSVHLKEGEQHVDDVSSALKRFLRDLPDGLFTRAQRLTWLEASEIEDEEEKVSRYREL LVRLPPVNRATVKALISHLYCVQCFSDTNQMNVHNLAIVFGPTLFQTDGQDYKAGRVVEDLINHYVVVFSVDEEELRKQREEITAIVKMR VAGTASGTQHAGDFICTVYLEEKKAETEQHIKVPASMTAEELTLEILDRRNVGIREKDYWTCFEVNEREEAERPLHFAEKVLPILHGLGT DSHLVVKKHQAMEAMLLYLASRVGDTKHGMMKFREDRSLLGLGLPSGGFHDRYFILNSSCLRLYKEVRNLSVSEARGKILHYQVTLQELT GGKAMTQNITGHTSWTTVIPRTGNWAVAVSAANSKGSSLPTRINIMNLCEAGLLAPRQVSANSEGMDNILVTWQPPRKDPSAVQEYVVEW RELHPGGDTQVPLNWLRSRPYNVSALISENIKSYICYEIRVYALSGDQGGCSSILGNSKHKAPLSGPHINAITEEKGSILISWNSIPVQE QMGCLLHYRIYWKERDSNSQPQLCEIPYRVSQNSHPINSLQPRVTYVLWMTALTAAGESSHGNEREFCLQGKANWMAFVAPSICIAIIMV -------------------------------------------------------------- >5760_5760_3_ARAP1-IL12RB2_ARAP1_chr11_72404369_ENST00000334211_IL12RB2_chr1_67816552_ENST00000541374_length(amino acids)=1461AA_BP=1148 MPTKEEESLLPSLSSPPQPQSEEPLSTLPQGPPQPPSPPPCPPEIPPKPVRLFPEFDDSDYDEVPEEGPGAPARVMTKKEEPPPSRVPRA VRVASLLSEGEELSGDDQGDEEEDDHAYEGVPNGGWHTSSLSLSLPSTIAAPHPMDGPPGGSTPVTPVIKAGWLDKNPPQGSYIYQKRWV RLDTDHLRYFDSNKDAYSKRFISVACISHVAAIGDQKFEVITNNRTFAFRAESDVERKEWMQALQQAMAEQRARARLSSAYLLGVPGSEQ PDRAGSLELRGFKNKLYVAVVGDKVQLYKNLEEYHLGIGITFIDMSVGNVKEVDRRSFDLTTPYRIFSFSADSELEKEQWLEAMQGAIAE ALSTSEVAERIWAAAPNRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTETLIELFLQLGNGAGNRFWAAN VPPSEALQPSSSPSTRRCHLEAKYREGKYRRYHPLFGNQEELDKALCAAVTTTDLAETQALLGCGAGINCFSGDPEAPTPLALAEQAGQT LQMEFLRNNRTTEVPRLDSMKPLEKHYSVVLPTVSHSGFLYKTASAGKLLQDRRAREEFSRRWCVLGDGVLSYFENERAVTPNGEIRASE IVCLAVPPPDTHGFEHTFEVYTEGERLYLFGLESAEQAHEWVKCIAKAFVPPLAEDLLARDFERLGRLPYKAGLSLQRAQEGWFSLSGSE LRAVFPEGPCEEPLQLRKLQELSIQGDSENQVLVLVERRRTLYIQGERRLDFMGWLGAIQKAAASMGDTLSEQQLGDSDIPVIVYRCVDY ITQCGLTSEGIYRKCGQTSKTQRLLESLRQDARSVHLKEGEQHVDDVSSALKRFLRDLPDGLFTRAQRLTWLEASEIEDEEEKVSRYREL LVRLPPVNRATVKALISHLYCVQCFSDTNQMNVHNLAIVFGPTLFQTDGQDYKAGRVVEDLINHYVVVFSVDEEELRKQREEITAIVKMR VAGTASGTQHAGDFICTVYLEEKKAETEQHIKVPASMTAEELTLEILDRRNVGIREKDYWTCFEVNEREEAERPLHFAEKVLPILHGLGT DSHLVVKKHQAMEAMLLYLASRVGDTKHGMMKFREDRSLLGLGLPSGGFHDRYFILNSSCLRLYKEVRNLSVSEARGKILHYQVTLQELT GGKAMTQNITGHTSWTTVIPRTGNWAVAVSAANSKGSSLPTRINIMNLCEAGLLAPRQVSANSEGMDNILVTWQPPRKDPSAVQEYVVEW RELHPGGDTQVPLNWLRSRPYNVSALISENIKSYICYEIRVYALSGDQGGCSSILGNSKHKAPLSGPHINAITEEKGSILISWNSIPVQE QMGCLLHYRIYWKERDSNSQPQLCEIPYRVSQNSHPINSLQPRVTYVLWMTALTAAGESSHGNEREFCLQGKANWMAFVAPSICIAIIMV -------------------------------------------------------------- >5760_5760_4_ARAP1-IL12RB2_ARAP1_chr11_72404369_ENST00000334211_IL12RB2_chr1_67816552_ENST00000544434_length(amino acids)=1578AA_BP=1148 MPTKEEESLLPSLSSPPQPQSEEPLSTLPQGPPQPPSPPPCPPEIPPKPVRLFPEFDDSDYDEVPEEGPGAPARVMTKKEEPPPSRVPRA VRVASLLSEGEELSGDDQGDEEEDDHAYEGVPNGGWHTSSLSLSLPSTIAAPHPMDGPPGGSTPVTPVIKAGWLDKNPPQGSYIYQKRWV RLDTDHLRYFDSNKDAYSKRFISVACISHVAAIGDQKFEVITNNRTFAFRAESDVERKEWMQALQQAMAEQRARARLSSAYLLGVPGSEQ PDRAGSLELRGFKNKLYVAVVGDKVQLYKNLEEYHLGIGITFIDMSVGNVKEVDRRSFDLTTPYRIFSFSADSELEKEQWLEAMQGAIAE ALSTSEVAERIWAAAPNRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTETLIELFLQLGNGAGNRFWAAN VPPSEALQPSSSPSTRRCHLEAKYREGKYRRYHPLFGNQEELDKALCAAVTTTDLAETQALLGCGAGINCFSGDPEAPTPLALAEQAGQT LQMEFLRNNRTTEVPRLDSMKPLEKHYSVVLPTVSHSGFLYKTASAGKLLQDRRAREEFSRRWCVLGDGVLSYFENERAVTPNGEIRASE IVCLAVPPPDTHGFEHTFEVYTEGERLYLFGLESAEQAHEWVKCIAKAFVPPLAEDLLARDFERLGRLPYKAGLSLQRAQEGWFSLSGSE LRAVFPEGPCEEPLQLRKLQELSIQGDSENQVLVLVERRRTLYIQGERRLDFMGWLGAIQKAAASMGDTLSEQQLGDSDIPVIVYRCVDY ITQCGLTSEGIYRKCGQTSKTQRLLESLRQDARSVHLKEGEQHVDDVSSALKRFLRDLPDGLFTRAQRLTWLEASEIEDEEEKVSRYREL LVRLPPVNRATVKALISHLYCVQCFSDTNQMNVHNLAIVFGPTLFQTDGQDYKAGRVVEDLINHYVVVFSVDEEELRKQREEITAIVKMR VAGTASGTQHAGDFICTVYLEEKKAETEQHIKVPASMTAEELTLEILDRRNVGIREKDYWTCFEVNEREEAERPLHFAEKVLPILHGLGT DSHLVVKKHQAMEAMLLYLASRVGDTKHGMMKFREDRSLLGLGLPSGGFHDRYFILNSSCLRLYKEVRNLSVSEARGKILHYQVTLQELT GGKAMTQNITGHTSWTTVIPRTGNWAVAVSAANSKGSSLPTRINIMNLCEAGLLAPRQVSANSEGMDNILVTWQPPRKDPSAVQEYVVEW RELHPGGDTQVPLNWLRSRPYNVSALISEIPYRVSQNSHPINSLQPRVTYVLWMTALTAAGESSHGNEREFCLQGKANWMAFVAPSICIA IIMVGIFSTHYFQQKVFVLLAALRPQWCSREIPDPANSTCAKKYPIAEEKTQLPLDRLLIDWPTPEDPEPLVISEVLHQVTPVFRHPPCS NWPQREKGIQGHQASEKDMMHSASSPPPPRALQAESRQLVDLYKVLESRGSDPKPENPACPWTVLPAGDLPTHDGYLPSNIDDLPSHEAP -------------------------------------------------------------- >5760_5760_5_ARAP1-IL12RB2_ARAP1_chr11_72404369_ENST00000359373_IL12RB2_chr1_67816552_ENST00000262345_length(amino acids)=1848AA_BP=1332 MDKALPVRPPLAGTMAEAGDAALSVAEWLRALHLEQYTGLFEQHGLVWATECQGLSDTRLMDMGMLLPGHRRRILAGLLRAHTSPAPAPR PTPRPVPMKRHIFRSPPVPATPPEPLPTTTEDEGLPAAPPIPPRRSCLPPTCFTTPSTAAPDPVLPPLPAKRHLAELSVPPVPPRTGPPR LLVSLPTKEEESLLPSLSSPPQPQSEEPLSTLPQGPPQPPSPPPCPPEIPPKPVRLFPEFDDSDYDEVPEEGPGAPARVMTKKEEPPPSR VPRAVRVASLLSEGEELSGDDQGDEEEDDHAYEGVPNGGWHTSSLSLSLPSTIAAPHPMDGPPGGSTPVTPVIKAGWLDKNPPQGSYIYQ KRWVRLDTDHLRYFDSNKDAYSKRFISVACISHVAAIGDQKFEVITNNRTFAFRAESDVERKEWMQALQQAMAEQRARARLSSAYLLGVP GSEQPDRAGSLELRGFKNKLYVAVVGDKVQLYKNLEEYHLGIGITFIDMSVGNVKEVDRRSFDLTTPYRIFSFSADSELEKEQWLEAMQG AIAEALSTSEVAERIWAAAPNRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTETLIELFLQLGNGAGNRF WAANVPPSEALQPSSSPSTRRCHLEAKYREGKYRRYHPLFGNQEELDKALCAAVTTTDLAETQALLGCGAGINCFSGDPEAPTPLALAEQ AGQTLQMEFLRNNRTTEVPRLDSMKPLEKHYSVVLPTVSHSGFLYKTASAGKLLQDRRAREEFSRRWCVLGDGVLSYFENERAVTPNGEI RASEIVCLAVPPPDTHGFEHTFEVYTEGERLYLFGLESAEQAHEWVKCIAKAFVPPLAEDLLARDFERLGRLPYKAGLSLQRAQEGWFSL SGSELRAVFPEGPCEEPLQLRKLQELSIQGDSENQVLVLVERRRTLYIQGERRLDFMGWLGAIQKAAASMGDTLSEQQLGDSDIPVIVYR CVDYITQCGLTSEGIYRKCGQTSKTQRLLESLRQDARSVHLKEGEQHVDDVSSALKRFLRDLPDGLFTRAQRLTWLEASEIEDEEEKVSR YRELLVRLPPVNRATVKALISHLYCVQCFSDTNQMNVHNLAIVFGPTLFQTDGQDYKAGRVVEDLINHYVVVFSVDEEELRKQREEITAI VKMRVAGTASGTQHAGDFICTVYLEEKKAETEQHIKVPASMTAEELTLEILDRRNVGIREKDYWTCFEVNEREEAERPLHFAEKVLPILH GLGTDSHLVVKKHQAMEAMLLYLASRVGDTKHGMMKFREDRSLLGLGLPSGGFHDRYFILNSSCLRLYKEVRNLSVSEARGKILHYQVTL QELTGGKAMTQNITGHTSWTTVIPRTGNWAVAVSAANSKGSSLPTRINIMNLCEAGLLAPRQVSANSEGMDNILVTWQPPRKDPSAVQEY VVEWRELHPGGDTQVPLNWLRSRPYNVSALISENIKSYICYEIRVYALSGDQGGCSSILGNSKHKAPLSGPHINAITEEKGSILISWNSI PVQEQMGCLLHYRIYWKERDSNSQPQLCEIPYRVSQNSHPINSLQPRVTYVLWMTALTAAGESSHGNEREFCLQGKANWMAFVAPSICIA IIMVGIFSTHYFQQKVFVLLAALRPQWCSREIPDPANSTCAKKYPIAEEKTQLPLDRLLIDWPTPEDPEPLVISEVLHQVTPVFRHPPCS NWPQREKGIQGHQASEKDMMHSASSPPPPRALQAESRQLVDLYKVLESRGSDPKPENPACPWTVLPAGDLPTHDGYLPSNIDDLPSHEAP -------------------------------------------------------------- >5760_5760_6_ARAP1-IL12RB2_ARAP1_chr11_72404369_ENST00000359373_IL12RB2_chr1_67816552_ENST00000371000_length(amino acids)=1645AA_BP=1332 MDKALPVRPPLAGTMAEAGDAALSVAEWLRALHLEQYTGLFEQHGLVWATECQGLSDTRLMDMGMLLPGHRRRILAGLLRAHTSPAPAPR PTPRPVPMKRHIFRSPPVPATPPEPLPTTTEDEGLPAAPPIPPRRSCLPPTCFTTPSTAAPDPVLPPLPAKRHLAELSVPPVPPRTGPPR LLVSLPTKEEESLLPSLSSPPQPQSEEPLSTLPQGPPQPPSPPPCPPEIPPKPVRLFPEFDDSDYDEVPEEGPGAPARVMTKKEEPPPSR VPRAVRVASLLSEGEELSGDDQGDEEEDDHAYEGVPNGGWHTSSLSLSLPSTIAAPHPMDGPPGGSTPVTPVIKAGWLDKNPPQGSYIYQ KRWVRLDTDHLRYFDSNKDAYSKRFISVACISHVAAIGDQKFEVITNNRTFAFRAESDVERKEWMQALQQAMAEQRARARLSSAYLLGVP GSEQPDRAGSLELRGFKNKLYVAVVGDKVQLYKNLEEYHLGIGITFIDMSVGNVKEVDRRSFDLTTPYRIFSFSADSELEKEQWLEAMQG AIAEALSTSEVAERIWAAAPNRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTETLIELFLQLGNGAGNRF WAANVPPSEALQPSSSPSTRRCHLEAKYREGKYRRYHPLFGNQEELDKALCAAVTTTDLAETQALLGCGAGINCFSGDPEAPTPLALAEQ AGQTLQMEFLRNNRTTEVPRLDSMKPLEKHYSVVLPTVSHSGFLYKTASAGKLLQDRRAREEFSRRWCVLGDGVLSYFENERAVTPNGEI RASEIVCLAVPPPDTHGFEHTFEVYTEGERLYLFGLESAEQAHEWVKCIAKAFVPPLAEDLLARDFERLGRLPYKAGLSLQRAQEGWFSL SGSELRAVFPEGPCEEPLQLRKLQELSIQGDSENQVLVLVERRRTLYIQGERRLDFMGWLGAIQKAAASMGDTLSEQQLGDSDIPVIVYR CVDYITQCGLTSEGIYRKCGQTSKTQRLLESLRQDARSVHLKEGEQHVDDVSSALKRFLRDLPDGLFTRAQRLTWLEASEIEDEEEKVSR YRELLVRLPPVNRATVKALISHLYCVQCFSDTNQMNVHNLAIVFGPTLFQTDGQDYKAGRVVEDLINHYVVVFSVDEEELRKQREEITAI VKMRVAGTASGTQHAGDFICTVYLEEKKAETEQHIKVPASMTAEELTLEILDRRNVGIREKDYWTCFEVNEREEAERPLHFAEKVLPILH GLGTDSHLVVKKHQAMEAMLLYLASRVGDTKHGMMKFREDRSLLGLGLPSGGFHDRYFILNSSCLRLYKEVRNLSVSEARGKILHYQVTL QELTGGKAMTQNITGHTSWTTVIPRTGNWAVAVSAANSKGSSLPTRINIMNLCEAGLLAPRQVSANSEGMDNILVTWQPPRKDPSAVQEY VVEWRELHPGGDTQVPLNWLRSRPYNVSALISENIKSYICYEIRVYALSGDQGGCSSILGNSKHKAPLSGPHINAITEEKGSILISWNSI PVQEQMGCLLHYRIYWKERDSNSQPQLCEIPYRVSQNSHPINSLQPRVTYVLWMTALTAAGESSHGNEREFCLQGKANWMAFVAPSICIA -------------------------------------------------------------- >5760_5760_7_ARAP1-IL12RB2_ARAP1_chr11_72404369_ENST00000359373_IL12RB2_chr1_67816552_ENST00000541374_length(amino acids)=1645AA_BP=1332 MDKALPVRPPLAGTMAEAGDAALSVAEWLRALHLEQYTGLFEQHGLVWATECQGLSDTRLMDMGMLLPGHRRRILAGLLRAHTSPAPAPR PTPRPVPMKRHIFRSPPVPATPPEPLPTTTEDEGLPAAPPIPPRRSCLPPTCFTTPSTAAPDPVLPPLPAKRHLAELSVPPVPPRTGPPR LLVSLPTKEEESLLPSLSSPPQPQSEEPLSTLPQGPPQPPSPPPCPPEIPPKPVRLFPEFDDSDYDEVPEEGPGAPARVMTKKEEPPPSR VPRAVRVASLLSEGEELSGDDQGDEEEDDHAYEGVPNGGWHTSSLSLSLPSTIAAPHPMDGPPGGSTPVTPVIKAGWLDKNPPQGSYIYQ KRWVRLDTDHLRYFDSNKDAYSKRFISVACISHVAAIGDQKFEVITNNRTFAFRAESDVERKEWMQALQQAMAEQRARARLSSAYLLGVP GSEQPDRAGSLELRGFKNKLYVAVVGDKVQLYKNLEEYHLGIGITFIDMSVGNVKEVDRRSFDLTTPYRIFSFSADSELEKEQWLEAMQG AIAEALSTSEVAERIWAAAPNRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTETLIELFLQLGNGAGNRF WAANVPPSEALQPSSSPSTRRCHLEAKYREGKYRRYHPLFGNQEELDKALCAAVTTTDLAETQALLGCGAGINCFSGDPEAPTPLALAEQ AGQTLQMEFLRNNRTTEVPRLDSMKPLEKHYSVVLPTVSHSGFLYKTASAGKLLQDRRAREEFSRRWCVLGDGVLSYFENERAVTPNGEI RASEIVCLAVPPPDTHGFEHTFEVYTEGERLYLFGLESAEQAHEWVKCIAKAFVPPLAEDLLARDFERLGRLPYKAGLSLQRAQEGWFSL SGSELRAVFPEGPCEEPLQLRKLQELSIQGDSENQVLVLVERRRTLYIQGERRLDFMGWLGAIQKAAASMGDTLSEQQLGDSDIPVIVYR CVDYITQCGLTSEGIYRKCGQTSKTQRLLESLRQDARSVHLKEGEQHVDDVSSALKRFLRDLPDGLFTRAQRLTWLEASEIEDEEEKVSR YRELLVRLPPVNRATVKALISHLYCVQCFSDTNQMNVHNLAIVFGPTLFQTDGQDYKAGRVVEDLINHYVVVFSVDEEELRKQREEITAI VKMRVAGTASGTQHAGDFICTVYLEEKKAETEQHIKVPASMTAEELTLEILDRRNVGIREKDYWTCFEVNEREEAERPLHFAEKVLPILH GLGTDSHLVVKKHQAMEAMLLYLASRVGDTKHGMMKFREDRSLLGLGLPSGGFHDRYFILNSSCLRLYKEVRNLSVSEARGKILHYQVTL QELTGGKAMTQNITGHTSWTTVIPRTGNWAVAVSAANSKGSSLPTRINIMNLCEAGLLAPRQVSANSEGMDNILVTWQPPRKDPSAVQEY VVEWRELHPGGDTQVPLNWLRSRPYNVSALISENIKSYICYEIRVYALSGDQGGCSSILGNSKHKAPLSGPHINAITEEKGSILISWNSI PVQEQMGCLLHYRIYWKERDSNSQPQLCEIPYRVSQNSHPINSLQPRVTYVLWMTALTAAGESSHGNEREFCLQGKANWMAFVAPSICIA -------------------------------------------------------------- >5760_5760_8_ARAP1-IL12RB2_ARAP1_chr11_72404369_ENST00000359373_IL12RB2_chr1_67816552_ENST00000544434_length(amino acids)=1762AA_BP=1332 MDKALPVRPPLAGTMAEAGDAALSVAEWLRALHLEQYTGLFEQHGLVWATECQGLSDTRLMDMGMLLPGHRRRILAGLLRAHTSPAPAPR PTPRPVPMKRHIFRSPPVPATPPEPLPTTTEDEGLPAAPPIPPRRSCLPPTCFTTPSTAAPDPVLPPLPAKRHLAELSVPPVPPRTGPPR LLVSLPTKEEESLLPSLSSPPQPQSEEPLSTLPQGPPQPPSPPPCPPEIPPKPVRLFPEFDDSDYDEVPEEGPGAPARVMTKKEEPPPSR VPRAVRVASLLSEGEELSGDDQGDEEEDDHAYEGVPNGGWHTSSLSLSLPSTIAAPHPMDGPPGGSTPVTPVIKAGWLDKNPPQGSYIYQ KRWVRLDTDHLRYFDSNKDAYSKRFISVACISHVAAIGDQKFEVITNNRTFAFRAESDVERKEWMQALQQAMAEQRARARLSSAYLLGVP GSEQPDRAGSLELRGFKNKLYVAVVGDKVQLYKNLEEYHLGIGITFIDMSVGNVKEVDRRSFDLTTPYRIFSFSADSELEKEQWLEAMQG AIAEALSTSEVAERIWAAAPNRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTETLIELFLQLGNGAGNRF WAANVPPSEALQPSSSPSTRRCHLEAKYREGKYRRYHPLFGNQEELDKALCAAVTTTDLAETQALLGCGAGINCFSGDPEAPTPLALAEQ AGQTLQMEFLRNNRTTEVPRLDSMKPLEKHYSVVLPTVSHSGFLYKTASAGKLLQDRRAREEFSRRWCVLGDGVLSYFENERAVTPNGEI RASEIVCLAVPPPDTHGFEHTFEVYTEGERLYLFGLESAEQAHEWVKCIAKAFVPPLAEDLLARDFERLGRLPYKAGLSLQRAQEGWFSL SGSELRAVFPEGPCEEPLQLRKLQELSIQGDSENQVLVLVERRRTLYIQGERRLDFMGWLGAIQKAAASMGDTLSEQQLGDSDIPVIVYR CVDYITQCGLTSEGIYRKCGQTSKTQRLLESLRQDARSVHLKEGEQHVDDVSSALKRFLRDLPDGLFTRAQRLTWLEASEIEDEEEKVSR YRELLVRLPPVNRATVKALISHLYCVQCFSDTNQMNVHNLAIVFGPTLFQTDGQDYKAGRVVEDLINHYVVVFSVDEEELRKQREEITAI VKMRVAGTASGTQHAGDFICTVYLEEKKAETEQHIKVPASMTAEELTLEILDRRNVGIREKDYWTCFEVNEREEAERPLHFAEKVLPILH GLGTDSHLVVKKHQAMEAMLLYLASRVGDTKHGMMKFREDRSLLGLGLPSGGFHDRYFILNSSCLRLYKEVRNLSVSEARGKILHYQVTL QELTGGKAMTQNITGHTSWTTVIPRTGNWAVAVSAANSKGSSLPTRINIMNLCEAGLLAPRQVSANSEGMDNILVTWQPPRKDPSAVQEY VVEWRELHPGGDTQVPLNWLRSRPYNVSALISEIPYRVSQNSHPINSLQPRVTYVLWMTALTAAGESSHGNEREFCLQGKANWMAFVAPS ICIAIIMVGIFSTHYFQQKVFVLLAALRPQWCSREIPDPANSTCAKKYPIAEEKTQLPLDRLLIDWPTPEDPEPLVISEVLHQVTPVFRH PPCSNWPQREKGIQGHQASEKDMMHSASSPPPPRALQAESRQLVDLYKVLESRGSDPKPENPACPWTVLPAGDLPTHDGYLPSNIDDLPS -------------------------------------------------------------- >5760_5760_9_ARAP1-IL12RB2_ARAP1_chr11_72404369_ENST00000393605_IL12RB2_chr1_67816552_ENST00000262345_length(amino acids)=1598AA_BP=1082 MKGRMTLSGSRGQEEPPPSRVPRAVRVASLLSEGEELSGDDQGDEEEDDHAYEGVPNGGWHTSSLSLSLPSTIAAPHPMDGPPGGSTPVT PVIKAGWLDKNPPQGSYIYQKRWVRLDTDHLRYFDSNKDAYSKRFISVACISHVAAIGDQKFEVITNNRTFAFRAESDVERKEWMQALQQ AMAEQRARARLSSAYLLGVPGSEQPDRAGSLELRGFKNKLYVAVVGDKVQLYKNLEEYHLGIGITFIDMSVGNVKEVDRRSFDLTTPYRI FSFSADSELEKEQWLEAMQGAIAEALSTSEVAERIWAAAPNRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKV WTETLIELFLQLGNGAGNRFWAANVPPSEALQPSSSPSTRRCHLEAKYREGKYRRYHPLFGNQEELDKALCAAVTTTDLAETQALLGCGA GINCFSGDPEAPTPLALAEQAGQTLQMEFLRNNRTTEVPRLDSMKPLEKHYSVVLPTVSHSGFLYKTASAGKLLQDRRAREEFSRRWCVL GDGVLSYFENERAVTPNGEIRASEIVCLAVPPPDTHGFEHTFEVYTEGERLYLFGLESAEQAHEWVKCIAKAFVPPLAEDLLARDFERLG RLPYKAGLSLQRAQEGWFSLSGSELRAVFPEGPCEEPLQLRKLQELSIQGDSENQVLVLVERRRTLYIQGERRLDFMGWLGAIQKAAASM GDTLSEQQLGDSDIPVIVYRCVDYITQCGLTSEGIYRKCGQTSKTQRLLESLRQDARSVHLKEGEQHVDDVSSALKRFLRDLPDGLFTRA QRLTWLEASEIEDEEEKVSRYRELLVRLPPVNRATVKALISHLYCVQCFSDTNQMNVHNLAIVFGPTLFQTDGQDYKAGRVVEDLINHYV VVFSVDEEELRKQREEITAIVKMRVAGTASGTQHAGDFICTVYLEEKKAETEQHIKVPASMTAEELTLEILDRRNVGIREKDYWTCFEVN EREEAERPLHFAEKVLPILHGLGTDSHLVVKKHQAMEAMLLYLASRVGDTKHGMMKFREDRSLLGLGLPSGGFHDRYFILNSSCLRLYKE VRNLSVSEARGKILHYQVTLQELTGGKAMTQNITGHTSWTTVIPRTGNWAVAVSAANSKGSSLPTRINIMNLCEAGLLAPRQVSANSEGM DNILVTWQPPRKDPSAVQEYVVEWRELHPGGDTQVPLNWLRSRPYNVSALISENIKSYICYEIRVYALSGDQGGCSSILGNSKHKAPLSG PHINAITEEKGSILISWNSIPVQEQMGCLLHYRIYWKERDSNSQPQLCEIPYRVSQNSHPINSLQPRVTYVLWMTALTAAGESSHGNERE FCLQGKANWMAFVAPSICIAIIMVGIFSTHYFQQKVFVLLAALRPQWCSREIPDPANSTCAKKYPIAEEKTQLPLDRLLIDWPTPEDPEP LVISEVLHQVTPVFRHPPCSNWPQREKGIQGHQASEKDMMHSASSPPPPRALQAESRQLVDLYKVLESRGSDPKPENPACPWTVLPAGDL -------------------------------------------------------------- >5760_5760_10_ARAP1-IL12RB2_ARAP1_chr11_72404369_ENST00000393605_IL12RB2_chr1_67816552_ENST00000371000_length(amino acids)=1395AA_BP=1082 MKGRMTLSGSRGQEEPPPSRVPRAVRVASLLSEGEELSGDDQGDEEEDDHAYEGVPNGGWHTSSLSLSLPSTIAAPHPMDGPPGGSTPVT PVIKAGWLDKNPPQGSYIYQKRWVRLDTDHLRYFDSNKDAYSKRFISVACISHVAAIGDQKFEVITNNRTFAFRAESDVERKEWMQALQQ AMAEQRARARLSSAYLLGVPGSEQPDRAGSLELRGFKNKLYVAVVGDKVQLYKNLEEYHLGIGITFIDMSVGNVKEVDRRSFDLTTPYRI FSFSADSELEKEQWLEAMQGAIAEALSTSEVAERIWAAAPNRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKV WTETLIELFLQLGNGAGNRFWAANVPPSEALQPSSSPSTRRCHLEAKYREGKYRRYHPLFGNQEELDKALCAAVTTTDLAETQALLGCGA GINCFSGDPEAPTPLALAEQAGQTLQMEFLRNNRTTEVPRLDSMKPLEKHYSVVLPTVSHSGFLYKTASAGKLLQDRRAREEFSRRWCVL GDGVLSYFENERAVTPNGEIRASEIVCLAVPPPDTHGFEHTFEVYTEGERLYLFGLESAEQAHEWVKCIAKAFVPPLAEDLLARDFERLG RLPYKAGLSLQRAQEGWFSLSGSELRAVFPEGPCEEPLQLRKLQELSIQGDSENQVLVLVERRRTLYIQGERRLDFMGWLGAIQKAAASM GDTLSEQQLGDSDIPVIVYRCVDYITQCGLTSEGIYRKCGQTSKTQRLLESLRQDARSVHLKEGEQHVDDVSSALKRFLRDLPDGLFTRA QRLTWLEASEIEDEEEKVSRYRELLVRLPPVNRATVKALISHLYCVQCFSDTNQMNVHNLAIVFGPTLFQTDGQDYKAGRVVEDLINHYV VVFSVDEEELRKQREEITAIVKMRVAGTASGTQHAGDFICTVYLEEKKAETEQHIKVPASMTAEELTLEILDRRNVGIREKDYWTCFEVN EREEAERPLHFAEKVLPILHGLGTDSHLVVKKHQAMEAMLLYLASRVGDTKHGMMKFREDRSLLGLGLPSGGFHDRYFILNSSCLRLYKE VRNLSVSEARGKILHYQVTLQELTGGKAMTQNITGHTSWTTVIPRTGNWAVAVSAANSKGSSLPTRINIMNLCEAGLLAPRQVSANSEGM DNILVTWQPPRKDPSAVQEYVVEWRELHPGGDTQVPLNWLRSRPYNVSALISENIKSYICYEIRVYALSGDQGGCSSILGNSKHKAPLSG PHINAITEEKGSILISWNSIPVQEQMGCLLHYRIYWKERDSNSQPQLCEIPYRVSQNSHPINSLQPRVTYVLWMTALTAAGESSHGNERE -------------------------------------------------------------- >5760_5760_11_ARAP1-IL12RB2_ARAP1_chr11_72404369_ENST00000393605_IL12RB2_chr1_67816552_ENST00000541374_length(amino acids)=1395AA_BP=1082 MKGRMTLSGSRGQEEPPPSRVPRAVRVASLLSEGEELSGDDQGDEEEDDHAYEGVPNGGWHTSSLSLSLPSTIAAPHPMDGPPGGSTPVT PVIKAGWLDKNPPQGSYIYQKRWVRLDTDHLRYFDSNKDAYSKRFISVACISHVAAIGDQKFEVITNNRTFAFRAESDVERKEWMQALQQ AMAEQRARARLSSAYLLGVPGSEQPDRAGSLELRGFKNKLYVAVVGDKVQLYKNLEEYHLGIGITFIDMSVGNVKEVDRRSFDLTTPYRI FSFSADSELEKEQWLEAMQGAIAEALSTSEVAERIWAAAPNRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKV WTETLIELFLQLGNGAGNRFWAANVPPSEALQPSSSPSTRRCHLEAKYREGKYRRYHPLFGNQEELDKALCAAVTTTDLAETQALLGCGA GINCFSGDPEAPTPLALAEQAGQTLQMEFLRNNRTTEVPRLDSMKPLEKHYSVVLPTVSHSGFLYKTASAGKLLQDRRAREEFSRRWCVL GDGVLSYFENERAVTPNGEIRASEIVCLAVPPPDTHGFEHTFEVYTEGERLYLFGLESAEQAHEWVKCIAKAFVPPLAEDLLARDFERLG RLPYKAGLSLQRAQEGWFSLSGSELRAVFPEGPCEEPLQLRKLQELSIQGDSENQVLVLVERRRTLYIQGERRLDFMGWLGAIQKAAASM GDTLSEQQLGDSDIPVIVYRCVDYITQCGLTSEGIYRKCGQTSKTQRLLESLRQDARSVHLKEGEQHVDDVSSALKRFLRDLPDGLFTRA QRLTWLEASEIEDEEEKVSRYRELLVRLPPVNRATVKALISHLYCVQCFSDTNQMNVHNLAIVFGPTLFQTDGQDYKAGRVVEDLINHYV VVFSVDEEELRKQREEITAIVKMRVAGTASGTQHAGDFICTVYLEEKKAETEQHIKVPASMTAEELTLEILDRRNVGIREKDYWTCFEVN EREEAERPLHFAEKVLPILHGLGTDSHLVVKKHQAMEAMLLYLASRVGDTKHGMMKFREDRSLLGLGLPSGGFHDRYFILNSSCLRLYKE VRNLSVSEARGKILHYQVTLQELTGGKAMTQNITGHTSWTTVIPRTGNWAVAVSAANSKGSSLPTRINIMNLCEAGLLAPRQVSANSEGM DNILVTWQPPRKDPSAVQEYVVEWRELHPGGDTQVPLNWLRSRPYNVSALISENIKSYICYEIRVYALSGDQGGCSSILGNSKHKAPLSG PHINAITEEKGSILISWNSIPVQEQMGCLLHYRIYWKERDSNSQPQLCEIPYRVSQNSHPINSLQPRVTYVLWMTALTAAGESSHGNERE -------------------------------------------------------------- >5760_5760_12_ARAP1-IL12RB2_ARAP1_chr11_72404369_ENST00000393605_IL12RB2_chr1_67816552_ENST00000544434_length(amino acids)=1512AA_BP=1082 MKGRMTLSGSRGQEEPPPSRVPRAVRVASLLSEGEELSGDDQGDEEEDDHAYEGVPNGGWHTSSLSLSLPSTIAAPHPMDGPPGGSTPVT PVIKAGWLDKNPPQGSYIYQKRWVRLDTDHLRYFDSNKDAYSKRFISVACISHVAAIGDQKFEVITNNRTFAFRAESDVERKEWMQALQQ AMAEQRARARLSSAYLLGVPGSEQPDRAGSLELRGFKNKLYVAVVGDKVQLYKNLEEYHLGIGITFIDMSVGNVKEVDRRSFDLTTPYRI FSFSADSELEKEQWLEAMQGAIAEALSTSEVAERIWAAAPNRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKV WTETLIELFLQLGNGAGNRFWAANVPPSEALQPSSSPSTRRCHLEAKYREGKYRRYHPLFGNQEELDKALCAAVTTTDLAETQALLGCGA GINCFSGDPEAPTPLALAEQAGQTLQMEFLRNNRTTEVPRLDSMKPLEKHYSVVLPTVSHSGFLYKTASAGKLLQDRRAREEFSRRWCVL GDGVLSYFENERAVTPNGEIRASEIVCLAVPPPDTHGFEHTFEVYTEGERLYLFGLESAEQAHEWVKCIAKAFVPPLAEDLLARDFERLG RLPYKAGLSLQRAQEGWFSLSGSELRAVFPEGPCEEPLQLRKLQELSIQGDSENQVLVLVERRRTLYIQGERRLDFMGWLGAIQKAAASM GDTLSEQQLGDSDIPVIVYRCVDYITQCGLTSEGIYRKCGQTSKTQRLLESLRQDARSVHLKEGEQHVDDVSSALKRFLRDLPDGLFTRA QRLTWLEASEIEDEEEKVSRYRELLVRLPPVNRATVKALISHLYCVQCFSDTNQMNVHNLAIVFGPTLFQTDGQDYKAGRVVEDLINHYV VVFSVDEEELRKQREEITAIVKMRVAGTASGTQHAGDFICTVYLEEKKAETEQHIKVPASMTAEELTLEILDRRNVGIREKDYWTCFEVN EREEAERPLHFAEKVLPILHGLGTDSHLVVKKHQAMEAMLLYLASRVGDTKHGMMKFREDRSLLGLGLPSGGFHDRYFILNSSCLRLYKE VRNLSVSEARGKILHYQVTLQELTGGKAMTQNITGHTSWTTVIPRTGNWAVAVSAANSKGSSLPTRINIMNLCEAGLLAPRQVSANSEGM DNILVTWQPPRKDPSAVQEYVVEWRELHPGGDTQVPLNWLRSRPYNVSALISEIPYRVSQNSHPINSLQPRVTYVLWMTALTAAGESSHG NEREFCLQGKANWMAFVAPSICIAIIMVGIFSTHYFQQKVFVLLAALRPQWCSREIPDPANSTCAKKYPIAEEKTQLPLDRLLIDWPTPE DPEPLVISEVLHQVTPVFRHPPCSNWPQREKGIQGHQASEKDMMHSASSPPPPRALQAESRQLVDLYKVLESRGSDPKPENPACPWTVLP -------------------------------------------------------------- >5760_5760_13_ARAP1-IL12RB2_ARAP1_chr11_72404369_ENST00000426523_IL12RB2_chr1_67816552_ENST00000262345_length(amino acids)=1664AA_BP=1148 MPTKEEESLLPSLSSPPQPQSEEPLSTLPQGPPQPPSPPPCPPEIPPKPVRLFPEFDDSDYDEVPEEGPGAPARVMTKKEEPPPSRVPRA VRVASLLSEGEELSGDDQGDEEEDDHAYEGVPNGGWHTSSLSLSLPSTIAAPHPMDGPPGGSTPVTPVIKAGWLDKNPPQGSYIYQKRWV RLDTDHLRYFDSNKDAYSKRFISVACISHVAAIGDQKFEVITNNRTFAFRAESDVERKEWMQALQQAMAEQRARARLSSAYLLGVPGSEQ PDRAGSLELRGFKNKLYVAVVGDKVQLYKNLEEYHLGIGITFIDMSVGNVKEVDRRSFDLTTPYRIFSFSADSELEKEQWLEAMQGAIAE ALSTSEVAERIWAAAPNRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTETLIELFLQLGNGAGNRFWAAN VPPSEALQPSSSPSTRRCHLEAKYREGKYRRYHPLFGNQEELDKALCAAVTTTDLAETQALLGCGAGINCFSGDPEAPTPLALAEQAGQT LQMEFLRNNRTTEVPRLDSMKPLEKHYSVVLPTVSHSGFLYKTASAGKLLQDRRAREEFSRRWCVLGDGVLSYFENERAVTPNGEIRASE IVCLAVPPPDTHGFEHTFEVYTEGERLYLFGLESAEQAHEWVKCIAKAFVPPLAEDLLARDFERLGRLPYKAGLSLQRAQEGWFSLSGSE LRAVFPEGPCEEPLQLRKLQELSIQGDSENQVLVLVERRRTLYIQGERRLDFMGWLGAIQKAAASMGDTLSEQQLGDSDIPVIVYRCVDY ITQCGLTSEGIYRKCGQTSKTQRLLESLRQDARSVHLKEGEQHVDDVSSALKRFLRDLPDGLFTRAQRLTWLEASEIEDEEEKVSRYREL LVRLPPVNRATVKALISHLYCVQCFSDTNQMNVHNLAIVFGPTLFQTDGQDYKAGRVVEDLINHYVVVFSVDEEELRKQREEITAIVKMR VAGTASGTQHAGDFICTVYLEEKKAETEQHIKVPASMTAEELTLEILDRRNVGIREKDYWTCFEVNEREEAERPLHFAEKVLPILHGLGT DSHLVVKKHQAMEAMLLYLASRVGDTKHGMMKFREDRSLLGLGLPSGGFHDRYFILNSSCLRLYKEVRNLSVSEARGKILHYQVTLQELT GGKAMTQNITGHTSWTTVIPRTGNWAVAVSAANSKGSSLPTRINIMNLCEAGLLAPRQVSANSEGMDNILVTWQPPRKDPSAVQEYVVEW RELHPGGDTQVPLNWLRSRPYNVSALISENIKSYICYEIRVYALSGDQGGCSSILGNSKHKAPLSGPHINAITEEKGSILISWNSIPVQE QMGCLLHYRIYWKERDSNSQPQLCEIPYRVSQNSHPINSLQPRVTYVLWMTALTAAGESSHGNEREFCLQGKANWMAFVAPSICIAIIMV GIFSTHYFQQKVFVLLAALRPQWCSREIPDPANSTCAKKYPIAEEKTQLPLDRLLIDWPTPEDPEPLVISEVLHQVTPVFRHPPCSNWPQ REKGIQGHQASEKDMMHSASSPPPPRALQAESRQLVDLYKVLESRGSDPKPENPACPWTVLPAGDLPTHDGYLPSNIDDLPSHEAPLADS -------------------------------------------------------------- >5760_5760_14_ARAP1-IL12RB2_ARAP1_chr11_72404369_ENST00000426523_IL12RB2_chr1_67816552_ENST00000371000_length(amino acids)=1461AA_BP=1148 MPTKEEESLLPSLSSPPQPQSEEPLSTLPQGPPQPPSPPPCPPEIPPKPVRLFPEFDDSDYDEVPEEGPGAPARVMTKKEEPPPSRVPRA VRVASLLSEGEELSGDDQGDEEEDDHAYEGVPNGGWHTSSLSLSLPSTIAAPHPMDGPPGGSTPVTPVIKAGWLDKNPPQGSYIYQKRWV RLDTDHLRYFDSNKDAYSKRFISVACISHVAAIGDQKFEVITNNRTFAFRAESDVERKEWMQALQQAMAEQRARARLSSAYLLGVPGSEQ PDRAGSLELRGFKNKLYVAVVGDKVQLYKNLEEYHLGIGITFIDMSVGNVKEVDRRSFDLTTPYRIFSFSADSELEKEQWLEAMQGAIAE ALSTSEVAERIWAAAPNRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTETLIELFLQLGNGAGNRFWAAN VPPSEALQPSSSPSTRRCHLEAKYREGKYRRYHPLFGNQEELDKALCAAVTTTDLAETQALLGCGAGINCFSGDPEAPTPLALAEQAGQT LQMEFLRNNRTTEVPRLDSMKPLEKHYSVVLPTVSHSGFLYKTASAGKLLQDRRAREEFSRRWCVLGDGVLSYFENERAVTPNGEIRASE IVCLAVPPPDTHGFEHTFEVYTEGERLYLFGLESAEQAHEWVKCIAKAFVPPLAEDLLARDFERLGRLPYKAGLSLQRAQEGWFSLSGSE LRAVFPEGPCEEPLQLRKLQELSIQGDSENQVLVLVERRRTLYIQGERRLDFMGWLGAIQKAAASMGDTLSEQQLGDSDIPVIVYRCVDY ITQCGLTSEGIYRKCGQTSKTQRLLESLRQDARSVHLKEGEQHVDDVSSALKRFLRDLPDGLFTRAQRLTWLEASEIEDEEEKVSRYREL LVRLPPVNRATVKALISHLYCVQCFSDTNQMNVHNLAIVFGPTLFQTDGQDYKAGRVVEDLINHYVVVFSVDEEELRKQREEITAIVKMR VAGTASGTQHAGDFICTVYLEEKKAETEQHIKVPASMTAEELTLEILDRRNVGIREKDYWTCFEVNEREEAERPLHFAEKVLPILHGLGT DSHLVVKKHQAMEAMLLYLASRVGDTKHGMMKFREDRSLLGLGLPSGGFHDRYFILNSSCLRLYKEVRNLSVSEARGKILHYQVTLQELT GGKAMTQNITGHTSWTTVIPRTGNWAVAVSAANSKGSSLPTRINIMNLCEAGLLAPRQVSANSEGMDNILVTWQPPRKDPSAVQEYVVEW RELHPGGDTQVPLNWLRSRPYNVSALISENIKSYICYEIRVYALSGDQGGCSSILGNSKHKAPLSGPHINAITEEKGSILISWNSIPVQE QMGCLLHYRIYWKERDSNSQPQLCEIPYRVSQNSHPINSLQPRVTYVLWMTALTAAGESSHGNEREFCLQGKANWMAFVAPSICIAIIMV -------------------------------------------------------------- >5760_5760_15_ARAP1-IL12RB2_ARAP1_chr11_72404369_ENST00000426523_IL12RB2_chr1_67816552_ENST00000541374_length(amino acids)=1461AA_BP=1148 MPTKEEESLLPSLSSPPQPQSEEPLSTLPQGPPQPPSPPPCPPEIPPKPVRLFPEFDDSDYDEVPEEGPGAPARVMTKKEEPPPSRVPRA VRVASLLSEGEELSGDDQGDEEEDDHAYEGVPNGGWHTSSLSLSLPSTIAAPHPMDGPPGGSTPVTPVIKAGWLDKNPPQGSYIYQKRWV RLDTDHLRYFDSNKDAYSKRFISVACISHVAAIGDQKFEVITNNRTFAFRAESDVERKEWMQALQQAMAEQRARARLSSAYLLGVPGSEQ PDRAGSLELRGFKNKLYVAVVGDKVQLYKNLEEYHLGIGITFIDMSVGNVKEVDRRSFDLTTPYRIFSFSADSELEKEQWLEAMQGAIAE ALSTSEVAERIWAAAPNRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTETLIELFLQLGNGAGNRFWAAN VPPSEALQPSSSPSTRRCHLEAKYREGKYRRYHPLFGNQEELDKALCAAVTTTDLAETQALLGCGAGINCFSGDPEAPTPLALAEQAGQT LQMEFLRNNRTTEVPRLDSMKPLEKHYSVVLPTVSHSGFLYKTASAGKLLQDRRAREEFSRRWCVLGDGVLSYFENERAVTPNGEIRASE IVCLAVPPPDTHGFEHTFEVYTEGERLYLFGLESAEQAHEWVKCIAKAFVPPLAEDLLARDFERLGRLPYKAGLSLQRAQEGWFSLSGSE LRAVFPEGPCEEPLQLRKLQELSIQGDSENQVLVLVERRRTLYIQGERRLDFMGWLGAIQKAAASMGDTLSEQQLGDSDIPVIVYRCVDY ITQCGLTSEGIYRKCGQTSKTQRLLESLRQDARSVHLKEGEQHVDDVSSALKRFLRDLPDGLFTRAQRLTWLEASEIEDEEEKVSRYREL LVRLPPVNRATVKALISHLYCVQCFSDTNQMNVHNLAIVFGPTLFQTDGQDYKAGRVVEDLINHYVVVFSVDEEELRKQREEITAIVKMR VAGTASGTQHAGDFICTVYLEEKKAETEQHIKVPASMTAEELTLEILDRRNVGIREKDYWTCFEVNEREEAERPLHFAEKVLPILHGLGT DSHLVVKKHQAMEAMLLYLASRVGDTKHGMMKFREDRSLLGLGLPSGGFHDRYFILNSSCLRLYKEVRNLSVSEARGKILHYQVTLQELT GGKAMTQNITGHTSWTTVIPRTGNWAVAVSAANSKGSSLPTRINIMNLCEAGLLAPRQVSANSEGMDNILVTWQPPRKDPSAVQEYVVEW RELHPGGDTQVPLNWLRSRPYNVSALISENIKSYICYEIRVYALSGDQGGCSSILGNSKHKAPLSGPHINAITEEKGSILISWNSIPVQE QMGCLLHYRIYWKERDSNSQPQLCEIPYRVSQNSHPINSLQPRVTYVLWMTALTAAGESSHGNEREFCLQGKANWMAFVAPSICIAIIMV -------------------------------------------------------------- >5760_5760_16_ARAP1-IL12RB2_ARAP1_chr11_72404369_ENST00000426523_IL12RB2_chr1_67816552_ENST00000544434_length(amino acids)=1578AA_BP=1148 MPTKEEESLLPSLSSPPQPQSEEPLSTLPQGPPQPPSPPPCPPEIPPKPVRLFPEFDDSDYDEVPEEGPGAPARVMTKKEEPPPSRVPRA VRVASLLSEGEELSGDDQGDEEEDDHAYEGVPNGGWHTSSLSLSLPSTIAAPHPMDGPPGGSTPVTPVIKAGWLDKNPPQGSYIYQKRWV RLDTDHLRYFDSNKDAYSKRFISVACISHVAAIGDQKFEVITNNRTFAFRAESDVERKEWMQALQQAMAEQRARARLSSAYLLGVPGSEQ PDRAGSLELRGFKNKLYVAVVGDKVQLYKNLEEYHLGIGITFIDMSVGNVKEVDRRSFDLTTPYRIFSFSADSELEKEQWLEAMQGAIAE ALSTSEVAERIWAAAPNRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTETLIELFLQLGNGAGNRFWAAN VPPSEALQPSSSPSTRRCHLEAKYREGKYRRYHPLFGNQEELDKALCAAVTTTDLAETQALLGCGAGINCFSGDPEAPTPLALAEQAGQT LQMEFLRNNRTTEVPRLDSMKPLEKHYSVVLPTVSHSGFLYKTASAGKLLQDRRAREEFSRRWCVLGDGVLSYFENERAVTPNGEIRASE IVCLAVPPPDTHGFEHTFEVYTEGERLYLFGLESAEQAHEWVKCIAKAFVPPLAEDLLARDFERLGRLPYKAGLSLQRAQEGWFSLSGSE LRAVFPEGPCEEPLQLRKLQELSIQGDSENQVLVLVERRRTLYIQGERRLDFMGWLGAIQKAAASMGDTLSEQQLGDSDIPVIVYRCVDY ITQCGLTSEGIYRKCGQTSKTQRLLESLRQDARSVHLKEGEQHVDDVSSALKRFLRDLPDGLFTRAQRLTWLEASEIEDEEEKVSRYREL LVRLPPVNRATVKALISHLYCVQCFSDTNQMNVHNLAIVFGPTLFQTDGQDYKAGRVVEDLINHYVVVFSVDEEELRKQREEITAIVKMR VAGTASGTQHAGDFICTVYLEEKKAETEQHIKVPASMTAEELTLEILDRRNVGIREKDYWTCFEVNEREEAERPLHFAEKVLPILHGLGT DSHLVVKKHQAMEAMLLYLASRVGDTKHGMMKFREDRSLLGLGLPSGGFHDRYFILNSSCLRLYKEVRNLSVSEARGKILHYQVTLQELT GGKAMTQNITGHTSWTTVIPRTGNWAVAVSAANSKGSSLPTRINIMNLCEAGLLAPRQVSANSEGMDNILVTWQPPRKDPSAVQEYVVEW RELHPGGDTQVPLNWLRSRPYNVSALISEIPYRVSQNSHPINSLQPRVTYVLWMTALTAAGESSHGNEREFCLQGKANWMAFVAPSICIA IIMVGIFSTHYFQQKVFVLLAALRPQWCSREIPDPANSTCAKKYPIAEEKTQLPLDRLLIDWPTPEDPEPLVISEVLHQVTPVFRHPPCS NWPQREKGIQGHQASEKDMMHSASSPPPPRALQAESRQLVDLYKVLESRGSDPKPENPACPWTVLPAGDLPTHDGYLPSNIDDLPSHEAP -------------------------------------------------------------- >5760_5760_17_ARAP1-IL12RB2_ARAP1_chr11_72404369_ENST00000429686_IL12RB2_chr1_67816552_ENST00000262345_length(amino acids)=1603AA_BP=1087 MPTKEEESLLPSLSSPPQPQSEEPLSTLPQGPPQPPSPPPCPPEIPPKPVRLFPEFDDSDYDEVPEEGPGAPARVMTKKEEPPPSRVPRA VRVASLLSEGEELSGDDQGDEEEDDHAYEGVPNGGWHTSSLSLSLPSTIAAPHPMDGPPGGSTPVTPVIKAGWLDKNPPQGSYIYQKRWV RLDTDHLRYFDSNKDAYSKRFISVACISHVAAIGDQKFEVITNNRTFAFRAESDVERKEWMQALQQAMAEQRARARLSSAYLLGVPGSEQ PDRAGSLELRGFKNKLYVAVVGDKVQLYKNLEEYHLGIGITFIDMSVGNVKEVDRRSFDLTTPYRIFSFSADSELEKEQWLEAMQGAIAE ALSTSEVAERIWAAAPNRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTETLIEALCAAVTTTDLAETQAL LGCGAGINCFSGDPEAPTPLALAEQAGQTLQMEFLRNNRTTEVPRLDSMKPLEKHYSVVLPTVSHSGFLYKTASAGKLLQDRRAREEFSR RWCVLGDGVLSYFENERAVTPNGEIRASEIVCLAVPPPDTHGFEHTFEVYTEGERLYLFGLESAEQAHEWVKCIAKAFVPPLAEDLLARD FERLGRLPYKAGLSLQRAQEGWFSLSGSELRAVFPEGPCEEPLQLRKLQELSIQGDSENQVLVLVERRRTLYIQGERRLDFMGWLGAIQK AAASMGDTLSEQQLGDSDIPVIVYRCVDYITQCGLTSEGIYRKCGQTSKTQRLLESLRQDARSVHLKEGEQHVDDVSSALKRFLRDLPDG LFTRAQRLTWLEASEIEDEEEKVSRYRELLVRLPPVNRATVKALISHLYCVQCFSDTNQMNVHNLAIVFGPTLFQTDGQDYKAGRVVEDL INHYVVVFSVDEEELRKQREEITAIVKMRVAGTASGTQHAGDFICTVYLEEKKAETEQHIKVPASMTAEELTLEILDRRNVGIREKDYWT CFEVNEREEAERPLHFAEKVLPILHGLGTDSHLVVKKHQAMEAMLLYLASRVGDTKHGMMKFREDRSLLGLGLPSGGFHDRYFILNSSCL RLYKEVRNLSVSEARGKILHYQVTLQELTGGKAMTQNITGHTSWTTVIPRTGNWAVAVSAANSKGSSLPTRINIMNLCEAGLLAPRQVSA NSEGMDNILVTWQPPRKDPSAVQEYVVEWRELHPGGDTQVPLNWLRSRPYNVSALISENIKSYICYEIRVYALSGDQGGCSSILGNSKHK APLSGPHINAITEEKGSILISWNSIPVQEQMGCLLHYRIYWKERDSNSQPQLCEIPYRVSQNSHPINSLQPRVTYVLWMTALTAAGESSH GNEREFCLQGKANWMAFVAPSICIAIIMVGIFSTHYFQQKVFVLLAALRPQWCSREIPDPANSTCAKKYPIAEEKTQLPLDRLLIDWPTP EDPEPLVISEVLHQVTPVFRHPPCSNWPQREKGIQGHQASEKDMMHSASSPPPPRALQAESRQLVDLYKVLESRGSDPKPENPACPWTVL -------------------------------------------------------------- >5760_5760_18_ARAP1-IL12RB2_ARAP1_chr11_72404369_ENST00000429686_IL12RB2_chr1_67816552_ENST00000371000_length(amino acids)=1400AA_BP=1087 MPTKEEESLLPSLSSPPQPQSEEPLSTLPQGPPQPPSPPPCPPEIPPKPVRLFPEFDDSDYDEVPEEGPGAPARVMTKKEEPPPSRVPRA VRVASLLSEGEELSGDDQGDEEEDDHAYEGVPNGGWHTSSLSLSLPSTIAAPHPMDGPPGGSTPVTPVIKAGWLDKNPPQGSYIYQKRWV RLDTDHLRYFDSNKDAYSKRFISVACISHVAAIGDQKFEVITNNRTFAFRAESDVERKEWMQALQQAMAEQRARARLSSAYLLGVPGSEQ PDRAGSLELRGFKNKLYVAVVGDKVQLYKNLEEYHLGIGITFIDMSVGNVKEVDRRSFDLTTPYRIFSFSADSELEKEQWLEAMQGAIAE ALSTSEVAERIWAAAPNRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTETLIEALCAAVTTTDLAETQAL LGCGAGINCFSGDPEAPTPLALAEQAGQTLQMEFLRNNRTTEVPRLDSMKPLEKHYSVVLPTVSHSGFLYKTASAGKLLQDRRAREEFSR RWCVLGDGVLSYFENERAVTPNGEIRASEIVCLAVPPPDTHGFEHTFEVYTEGERLYLFGLESAEQAHEWVKCIAKAFVPPLAEDLLARD FERLGRLPYKAGLSLQRAQEGWFSLSGSELRAVFPEGPCEEPLQLRKLQELSIQGDSENQVLVLVERRRTLYIQGERRLDFMGWLGAIQK AAASMGDTLSEQQLGDSDIPVIVYRCVDYITQCGLTSEGIYRKCGQTSKTQRLLESLRQDARSVHLKEGEQHVDDVSSALKRFLRDLPDG LFTRAQRLTWLEASEIEDEEEKVSRYRELLVRLPPVNRATVKALISHLYCVQCFSDTNQMNVHNLAIVFGPTLFQTDGQDYKAGRVVEDL INHYVVVFSVDEEELRKQREEITAIVKMRVAGTASGTQHAGDFICTVYLEEKKAETEQHIKVPASMTAEELTLEILDRRNVGIREKDYWT CFEVNEREEAERPLHFAEKVLPILHGLGTDSHLVVKKHQAMEAMLLYLASRVGDTKHGMMKFREDRSLLGLGLPSGGFHDRYFILNSSCL RLYKEVRNLSVSEARGKILHYQVTLQELTGGKAMTQNITGHTSWTTVIPRTGNWAVAVSAANSKGSSLPTRINIMNLCEAGLLAPRQVSA NSEGMDNILVTWQPPRKDPSAVQEYVVEWRELHPGGDTQVPLNWLRSRPYNVSALISENIKSYICYEIRVYALSGDQGGCSSILGNSKHK APLSGPHINAITEEKGSILISWNSIPVQEQMGCLLHYRIYWKERDSNSQPQLCEIPYRVSQNSHPINSLQPRVTYVLWMTALTAAGESSH -------------------------------------------------------------- >5760_5760_19_ARAP1-IL12RB2_ARAP1_chr11_72404369_ENST00000429686_IL12RB2_chr1_67816552_ENST00000541374_length(amino acids)=1400AA_BP=1087 MPTKEEESLLPSLSSPPQPQSEEPLSTLPQGPPQPPSPPPCPPEIPPKPVRLFPEFDDSDYDEVPEEGPGAPARVMTKKEEPPPSRVPRA VRVASLLSEGEELSGDDQGDEEEDDHAYEGVPNGGWHTSSLSLSLPSTIAAPHPMDGPPGGSTPVTPVIKAGWLDKNPPQGSYIYQKRWV RLDTDHLRYFDSNKDAYSKRFISVACISHVAAIGDQKFEVITNNRTFAFRAESDVERKEWMQALQQAMAEQRARARLSSAYLLGVPGSEQ PDRAGSLELRGFKNKLYVAVVGDKVQLYKNLEEYHLGIGITFIDMSVGNVKEVDRRSFDLTTPYRIFSFSADSELEKEQWLEAMQGAIAE ALSTSEVAERIWAAAPNRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTETLIEALCAAVTTTDLAETQAL LGCGAGINCFSGDPEAPTPLALAEQAGQTLQMEFLRNNRTTEVPRLDSMKPLEKHYSVVLPTVSHSGFLYKTASAGKLLQDRRAREEFSR RWCVLGDGVLSYFENERAVTPNGEIRASEIVCLAVPPPDTHGFEHTFEVYTEGERLYLFGLESAEQAHEWVKCIAKAFVPPLAEDLLARD FERLGRLPYKAGLSLQRAQEGWFSLSGSELRAVFPEGPCEEPLQLRKLQELSIQGDSENQVLVLVERRRTLYIQGERRLDFMGWLGAIQK AAASMGDTLSEQQLGDSDIPVIVYRCVDYITQCGLTSEGIYRKCGQTSKTQRLLESLRQDARSVHLKEGEQHVDDVSSALKRFLRDLPDG LFTRAQRLTWLEASEIEDEEEKVSRYRELLVRLPPVNRATVKALISHLYCVQCFSDTNQMNVHNLAIVFGPTLFQTDGQDYKAGRVVEDL INHYVVVFSVDEEELRKQREEITAIVKMRVAGTASGTQHAGDFICTVYLEEKKAETEQHIKVPASMTAEELTLEILDRRNVGIREKDYWT CFEVNEREEAERPLHFAEKVLPILHGLGTDSHLVVKKHQAMEAMLLYLASRVGDTKHGMMKFREDRSLLGLGLPSGGFHDRYFILNSSCL RLYKEVRNLSVSEARGKILHYQVTLQELTGGKAMTQNITGHTSWTTVIPRTGNWAVAVSAANSKGSSLPTRINIMNLCEAGLLAPRQVSA NSEGMDNILVTWQPPRKDPSAVQEYVVEWRELHPGGDTQVPLNWLRSRPYNVSALISENIKSYICYEIRVYALSGDQGGCSSILGNSKHK APLSGPHINAITEEKGSILISWNSIPVQEQMGCLLHYRIYWKERDSNSQPQLCEIPYRVSQNSHPINSLQPRVTYVLWMTALTAAGESSH -------------------------------------------------------------- >5760_5760_20_ARAP1-IL12RB2_ARAP1_chr11_72404369_ENST00000429686_IL12RB2_chr1_67816552_ENST00000544434_length(amino acids)=1517AA_BP=1087 MPTKEEESLLPSLSSPPQPQSEEPLSTLPQGPPQPPSPPPCPPEIPPKPVRLFPEFDDSDYDEVPEEGPGAPARVMTKKEEPPPSRVPRA VRVASLLSEGEELSGDDQGDEEEDDHAYEGVPNGGWHTSSLSLSLPSTIAAPHPMDGPPGGSTPVTPVIKAGWLDKNPPQGSYIYQKRWV RLDTDHLRYFDSNKDAYSKRFISVACISHVAAIGDQKFEVITNNRTFAFRAESDVERKEWMQALQQAMAEQRARARLSSAYLLGVPGSEQ PDRAGSLELRGFKNKLYVAVVGDKVQLYKNLEEYHLGIGITFIDMSVGNVKEVDRRSFDLTTPYRIFSFSADSELEKEQWLEAMQGAIAE ALSTSEVAERIWAAAPNRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTETLIEALCAAVTTTDLAETQAL LGCGAGINCFSGDPEAPTPLALAEQAGQTLQMEFLRNNRTTEVPRLDSMKPLEKHYSVVLPTVSHSGFLYKTASAGKLLQDRRAREEFSR RWCVLGDGVLSYFENERAVTPNGEIRASEIVCLAVPPPDTHGFEHTFEVYTEGERLYLFGLESAEQAHEWVKCIAKAFVPPLAEDLLARD FERLGRLPYKAGLSLQRAQEGWFSLSGSELRAVFPEGPCEEPLQLRKLQELSIQGDSENQVLVLVERRRTLYIQGERRLDFMGWLGAIQK AAASMGDTLSEQQLGDSDIPVIVYRCVDYITQCGLTSEGIYRKCGQTSKTQRLLESLRQDARSVHLKEGEQHVDDVSSALKRFLRDLPDG LFTRAQRLTWLEASEIEDEEEKVSRYRELLVRLPPVNRATVKALISHLYCVQCFSDTNQMNVHNLAIVFGPTLFQTDGQDYKAGRVVEDL INHYVVVFSVDEEELRKQREEITAIVKMRVAGTASGTQHAGDFICTVYLEEKKAETEQHIKVPASMTAEELTLEILDRRNVGIREKDYWT CFEVNEREEAERPLHFAEKVLPILHGLGTDSHLVVKKHQAMEAMLLYLASRVGDTKHGMMKFREDRSLLGLGLPSGGFHDRYFILNSSCL RLYKEVRNLSVSEARGKILHYQVTLQELTGGKAMTQNITGHTSWTTVIPRTGNWAVAVSAANSKGSSLPTRINIMNLCEAGLLAPRQVSA NSEGMDNILVTWQPPRKDPSAVQEYVVEWRELHPGGDTQVPLNWLRSRPYNVSALISEIPYRVSQNSHPINSLQPRVTYVLWMTALTAAG ESSHGNEREFCLQGKANWMAFVAPSICIAIIMVGIFSTHYFQQKVFVLLAALRPQWCSREIPDPANSTCAKKYPIAEEKTQLPLDRLLID WPTPEDPEPLVISEVLHQVTPVFRHPPCSNWPQREKGIQGHQASEKDMMHSASSPPPPRALQAESRQLVDLYKVLESRGSDPKPENPACP -------------------------------------------------------------- >5760_5760_21_ARAP1-IL12RB2_ARAP1_chr11_72404369_ENST00000455638_IL12RB2_chr1_67816552_ENST00000262345_length(amino acids)=1834AA_BP=1318 MAEAGDAALSVAEWLRALHLEQYTGLFEQHGLVWATECQGLSDTRLMDMGMLLPGHRRRILAGLLRAHTSPAPAPRPTPRPVPMKRHIFR SPPVPATPPEPLPTTTEDEGLPAAPPIPPRRSCLPPTCFTTPSTAAPDPVLPPLPAKRHLAELSVPPVPPRTGPPRLLVSLPTKEEESLL PSLSSPPQPQSEEPLSTLPQGPPQPPSPPPCPPEIPPKPVRLFPEFDDSDYDEVPEEGPGAPARVMTKKEEPPPSRVPRAVRVASLLSEG EELSGDDQGDEEEDDHAYEGVPNGGWHTSSLSLSLPSTIAAPHPMDGPPGGSTPVTPVIKAGWLDKNPPQGSYIYQKRWVRLDTDHLRYF DSNKDAYSKRFISVACISHVAAIGDQKFEVITNNRTFAFRAESDVERKEWMQALQQAMAEQRARARLSSAYLLGVPGSEQPDRAGSLELR GFKNKLYVAVVGDKVQLYKNLEEYHLGIGITFIDMSVGNVKEVDRRSFDLTTPYRIFSFSADSELEKEQWLEAMQGAIAEALSTSEVAER IWAAAPNRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTETLIELFLQLGNGAGNRFWAANVPPSEALQPS SSPSTRRCHLEAKYREGKYRRYHPLFGNQEELDKALCAAVTTTDLAETQALLGCGAGINCFSGDPEAPTPLALAEQAGQTLQMEFLRNNR TTEVPRLDSMKPLEKHYSVVLPTVSHSGFLYKTASAGKLLQDRRAREEFSRRWCVLGDGVLSYFENERAVTPNGEIRASEIVCLAVPPPD THGFEHTFEVYTEGERLYLFGLESAEQAHEWVKCIAKAFVPPLAEDLLARDFERLGRLPYKAGLSLQRAQEGWFSLSGSELRAVFPEGPC EEPLQLRKLQELSIQGDSENQVLVLVERRRTLYIQGERRLDFMGWLGAIQKAAASMGDTLSEQQLGDSDIPVIVYRCVDYITQCGLTSEG IYRKCGQTSKTQRLLESLRQDARSVHLKEGEQHVDDVSSALKRFLRDLPDGLFTRAQRLTWLEASEIEDEEEKVSRYRELLVRLPPVNRA TVKALISHLYCVQCFSDTNQMNVHNLAIVFGPTLFQTDGQDYKAGRVVEDLINHYVVVFSVDEEELRKQREEITAIVKMRVAGTASGTQH AGDFICTVYLEEKKAETEQHIKVPASMTAEELTLEILDRRNVGIREKDYWTCFEVNEREEAERPLHFAEKVLPILHGLGTDSHLVVKKHQ AMEAMLLYLASRVGDTKHGMMKFREDRSLLGLGLPSGGFHDRYFILNSSCLRLYKEVRNLSVSEARGKILHYQVTLQELTGGKAMTQNIT GHTSWTTVIPRTGNWAVAVSAANSKGSSLPTRINIMNLCEAGLLAPRQVSANSEGMDNILVTWQPPRKDPSAVQEYVVEWRELHPGGDTQ VPLNWLRSRPYNVSALISENIKSYICYEIRVYALSGDQGGCSSILGNSKHKAPLSGPHINAITEEKGSILISWNSIPVQEQMGCLLHYRI YWKERDSNSQPQLCEIPYRVSQNSHPINSLQPRVTYVLWMTALTAAGESSHGNEREFCLQGKANWMAFVAPSICIAIIMVGIFSTHYFQQ KVFVLLAALRPQWCSREIPDPANSTCAKKYPIAEEKTQLPLDRLLIDWPTPEDPEPLVISEVLHQVTPVFRHPPCSNWPQREKGIQGHQA SEKDMMHSASSPPPPRALQAESRQLVDLYKVLESRGSDPKPENPACPWTVLPAGDLPTHDGYLPSNIDDLPSHEAPLADSLEELEPQHIS -------------------------------------------------------------- >5760_5760_22_ARAP1-IL12RB2_ARAP1_chr11_72404369_ENST00000455638_IL12RB2_chr1_67816552_ENST00000371000_length(amino acids)=1631AA_BP=1318 MAEAGDAALSVAEWLRALHLEQYTGLFEQHGLVWATECQGLSDTRLMDMGMLLPGHRRRILAGLLRAHTSPAPAPRPTPRPVPMKRHIFR SPPVPATPPEPLPTTTEDEGLPAAPPIPPRRSCLPPTCFTTPSTAAPDPVLPPLPAKRHLAELSVPPVPPRTGPPRLLVSLPTKEEESLL PSLSSPPQPQSEEPLSTLPQGPPQPPSPPPCPPEIPPKPVRLFPEFDDSDYDEVPEEGPGAPARVMTKKEEPPPSRVPRAVRVASLLSEG EELSGDDQGDEEEDDHAYEGVPNGGWHTSSLSLSLPSTIAAPHPMDGPPGGSTPVTPVIKAGWLDKNPPQGSYIYQKRWVRLDTDHLRYF DSNKDAYSKRFISVACISHVAAIGDQKFEVITNNRTFAFRAESDVERKEWMQALQQAMAEQRARARLSSAYLLGVPGSEQPDRAGSLELR GFKNKLYVAVVGDKVQLYKNLEEYHLGIGITFIDMSVGNVKEVDRRSFDLTTPYRIFSFSADSELEKEQWLEAMQGAIAEALSTSEVAER IWAAAPNRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTETLIELFLQLGNGAGNRFWAANVPPSEALQPS SSPSTRRCHLEAKYREGKYRRYHPLFGNQEELDKALCAAVTTTDLAETQALLGCGAGINCFSGDPEAPTPLALAEQAGQTLQMEFLRNNR TTEVPRLDSMKPLEKHYSVVLPTVSHSGFLYKTASAGKLLQDRRAREEFSRRWCVLGDGVLSYFENERAVTPNGEIRASEIVCLAVPPPD THGFEHTFEVYTEGERLYLFGLESAEQAHEWVKCIAKAFVPPLAEDLLARDFERLGRLPYKAGLSLQRAQEGWFSLSGSELRAVFPEGPC EEPLQLRKLQELSIQGDSENQVLVLVERRRTLYIQGERRLDFMGWLGAIQKAAASMGDTLSEQQLGDSDIPVIVYRCVDYITQCGLTSEG IYRKCGQTSKTQRLLESLRQDARSVHLKEGEQHVDDVSSALKRFLRDLPDGLFTRAQRLTWLEASEIEDEEEKVSRYRELLVRLPPVNRA TVKALISHLYCVQCFSDTNQMNVHNLAIVFGPTLFQTDGQDYKAGRVVEDLINHYVVVFSVDEEELRKQREEITAIVKMRVAGTASGTQH AGDFICTVYLEEKKAETEQHIKVPASMTAEELTLEILDRRNVGIREKDYWTCFEVNEREEAERPLHFAEKVLPILHGLGTDSHLVVKKHQ AMEAMLLYLASRVGDTKHGMMKFREDRSLLGLGLPSGGFHDRYFILNSSCLRLYKEVRNLSVSEARGKILHYQVTLQELTGGKAMTQNIT GHTSWTTVIPRTGNWAVAVSAANSKGSSLPTRINIMNLCEAGLLAPRQVSANSEGMDNILVTWQPPRKDPSAVQEYVVEWRELHPGGDTQ VPLNWLRSRPYNVSALISENIKSYICYEIRVYALSGDQGGCSSILGNSKHKAPLSGPHINAITEEKGSILISWNSIPVQEQMGCLLHYRI YWKERDSNSQPQLCEIPYRVSQNSHPINSLQPRVTYVLWMTALTAAGESSHGNEREFCLQGKANWMAFVAPSICIAIIMVGIFSTHYFQQ -------------------------------------------------------------- >5760_5760_23_ARAP1-IL12RB2_ARAP1_chr11_72404369_ENST00000455638_IL12RB2_chr1_67816552_ENST00000541374_length(amino acids)=1631AA_BP=1318 MAEAGDAALSVAEWLRALHLEQYTGLFEQHGLVWATECQGLSDTRLMDMGMLLPGHRRRILAGLLRAHTSPAPAPRPTPRPVPMKRHIFR SPPVPATPPEPLPTTTEDEGLPAAPPIPPRRSCLPPTCFTTPSTAAPDPVLPPLPAKRHLAELSVPPVPPRTGPPRLLVSLPTKEEESLL PSLSSPPQPQSEEPLSTLPQGPPQPPSPPPCPPEIPPKPVRLFPEFDDSDYDEVPEEGPGAPARVMTKKEEPPPSRVPRAVRVASLLSEG EELSGDDQGDEEEDDHAYEGVPNGGWHTSSLSLSLPSTIAAPHPMDGPPGGSTPVTPVIKAGWLDKNPPQGSYIYQKRWVRLDTDHLRYF DSNKDAYSKRFISVACISHVAAIGDQKFEVITNNRTFAFRAESDVERKEWMQALQQAMAEQRARARLSSAYLLGVPGSEQPDRAGSLELR GFKNKLYVAVVGDKVQLYKNLEEYHLGIGITFIDMSVGNVKEVDRRSFDLTTPYRIFSFSADSELEKEQWLEAMQGAIAEALSTSEVAER IWAAAPNRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTETLIELFLQLGNGAGNRFWAANVPPSEALQPS SSPSTRRCHLEAKYREGKYRRYHPLFGNQEELDKALCAAVTTTDLAETQALLGCGAGINCFSGDPEAPTPLALAEQAGQTLQMEFLRNNR TTEVPRLDSMKPLEKHYSVVLPTVSHSGFLYKTASAGKLLQDRRAREEFSRRWCVLGDGVLSYFENERAVTPNGEIRASEIVCLAVPPPD THGFEHTFEVYTEGERLYLFGLESAEQAHEWVKCIAKAFVPPLAEDLLARDFERLGRLPYKAGLSLQRAQEGWFSLSGSELRAVFPEGPC EEPLQLRKLQELSIQGDSENQVLVLVERRRTLYIQGERRLDFMGWLGAIQKAAASMGDTLSEQQLGDSDIPVIVYRCVDYITQCGLTSEG IYRKCGQTSKTQRLLESLRQDARSVHLKEGEQHVDDVSSALKRFLRDLPDGLFTRAQRLTWLEASEIEDEEEKVSRYRELLVRLPPVNRA TVKALISHLYCVQCFSDTNQMNVHNLAIVFGPTLFQTDGQDYKAGRVVEDLINHYVVVFSVDEEELRKQREEITAIVKMRVAGTASGTQH AGDFICTVYLEEKKAETEQHIKVPASMTAEELTLEILDRRNVGIREKDYWTCFEVNEREEAERPLHFAEKVLPILHGLGTDSHLVVKKHQ AMEAMLLYLASRVGDTKHGMMKFREDRSLLGLGLPSGGFHDRYFILNSSCLRLYKEVRNLSVSEARGKILHYQVTLQELTGGKAMTQNIT GHTSWTTVIPRTGNWAVAVSAANSKGSSLPTRINIMNLCEAGLLAPRQVSANSEGMDNILVTWQPPRKDPSAVQEYVVEWRELHPGGDTQ VPLNWLRSRPYNVSALISENIKSYICYEIRVYALSGDQGGCSSILGNSKHKAPLSGPHINAITEEKGSILISWNSIPVQEQMGCLLHYRI YWKERDSNSQPQLCEIPYRVSQNSHPINSLQPRVTYVLWMTALTAAGESSHGNEREFCLQGKANWMAFVAPSICIAIIMVGIFSTHYFQQ -------------------------------------------------------------- >5760_5760_24_ARAP1-IL12RB2_ARAP1_chr11_72404369_ENST00000455638_IL12RB2_chr1_67816552_ENST00000544434_length(amino acids)=1748AA_BP=1318 MAEAGDAALSVAEWLRALHLEQYTGLFEQHGLVWATECQGLSDTRLMDMGMLLPGHRRRILAGLLRAHTSPAPAPRPTPRPVPMKRHIFR SPPVPATPPEPLPTTTEDEGLPAAPPIPPRRSCLPPTCFTTPSTAAPDPVLPPLPAKRHLAELSVPPVPPRTGPPRLLVSLPTKEEESLL PSLSSPPQPQSEEPLSTLPQGPPQPPSPPPCPPEIPPKPVRLFPEFDDSDYDEVPEEGPGAPARVMTKKEEPPPSRVPRAVRVASLLSEG EELSGDDQGDEEEDDHAYEGVPNGGWHTSSLSLSLPSTIAAPHPMDGPPGGSTPVTPVIKAGWLDKNPPQGSYIYQKRWVRLDTDHLRYF DSNKDAYSKRFISVACISHVAAIGDQKFEVITNNRTFAFRAESDVERKEWMQALQQAMAEQRARARLSSAYLLGVPGSEQPDRAGSLELR GFKNKLYVAVVGDKVQLYKNLEEYHLGIGITFIDMSVGNVKEVDRRSFDLTTPYRIFSFSADSELEKEQWLEAMQGAIAEALSTSEVAER IWAAAPNRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTETLIELFLQLGNGAGNRFWAANVPPSEALQPS SSPSTRRCHLEAKYREGKYRRYHPLFGNQEELDKALCAAVTTTDLAETQALLGCGAGINCFSGDPEAPTPLALAEQAGQTLQMEFLRNNR TTEVPRLDSMKPLEKHYSVVLPTVSHSGFLYKTASAGKLLQDRRAREEFSRRWCVLGDGVLSYFENERAVTPNGEIRASEIVCLAVPPPD THGFEHTFEVYTEGERLYLFGLESAEQAHEWVKCIAKAFVPPLAEDLLARDFERLGRLPYKAGLSLQRAQEGWFSLSGSELRAVFPEGPC EEPLQLRKLQELSIQGDSENQVLVLVERRRTLYIQGERRLDFMGWLGAIQKAAASMGDTLSEQQLGDSDIPVIVYRCVDYITQCGLTSEG IYRKCGQTSKTQRLLESLRQDARSVHLKEGEQHVDDVSSALKRFLRDLPDGLFTRAQRLTWLEASEIEDEEEKVSRYRELLVRLPPVNRA TVKALISHLYCVQCFSDTNQMNVHNLAIVFGPTLFQTDGQDYKAGRVVEDLINHYVVVFSVDEEELRKQREEITAIVKMRVAGTASGTQH AGDFICTVYLEEKKAETEQHIKVPASMTAEELTLEILDRRNVGIREKDYWTCFEVNEREEAERPLHFAEKVLPILHGLGTDSHLVVKKHQ AMEAMLLYLASRVGDTKHGMMKFREDRSLLGLGLPSGGFHDRYFILNSSCLRLYKEVRNLSVSEARGKILHYQVTLQELTGGKAMTQNIT GHTSWTTVIPRTGNWAVAVSAANSKGSSLPTRINIMNLCEAGLLAPRQVSANSEGMDNILVTWQPPRKDPSAVQEYVVEWRELHPGGDTQ VPLNWLRSRPYNVSALISEIPYRVSQNSHPINSLQPRVTYVLWMTALTAAGESSHGNEREFCLQGKANWMAFVAPSICIAIIMVGIFSTH YFQQKVFVLLAALRPQWCSREIPDPANSTCAKKYPIAEEKTQLPLDRLLIDWPTPEDPEPLVISEVLHQVTPVFRHPPCSNWPQREKGIQ GHQASEKDMMHSASSPPPPRALQAESRQLVDLYKVLESRGSDPKPENPACPWTVLPAGDLPTHDGYLPSNIDDLPSHEAPLADSLEELEP -------------------------------------------------------------- >5760_5760_25_ARAP1-IL12RB2_ARAP1_chr11_72404370_ENST00000334211_IL12RB2_chr1_67816553_ENST00000262345_length(amino acids)=1664AA_BP=1148 MPTKEEESLLPSLSSPPQPQSEEPLSTLPQGPPQPPSPPPCPPEIPPKPVRLFPEFDDSDYDEVPEEGPGAPARVMTKKEEPPPSRVPRA VRVASLLSEGEELSGDDQGDEEEDDHAYEGVPNGGWHTSSLSLSLPSTIAAPHPMDGPPGGSTPVTPVIKAGWLDKNPPQGSYIYQKRWV RLDTDHLRYFDSNKDAYSKRFISVACISHVAAIGDQKFEVITNNRTFAFRAESDVERKEWMQALQQAMAEQRARARLSSAYLLGVPGSEQ PDRAGSLELRGFKNKLYVAVVGDKVQLYKNLEEYHLGIGITFIDMSVGNVKEVDRRSFDLTTPYRIFSFSADSELEKEQWLEAMQGAIAE ALSTSEVAERIWAAAPNRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTETLIELFLQLGNGAGNRFWAAN VPPSEALQPSSSPSTRRCHLEAKYREGKYRRYHPLFGNQEELDKALCAAVTTTDLAETQALLGCGAGINCFSGDPEAPTPLALAEQAGQT LQMEFLRNNRTTEVPRLDSMKPLEKHYSVVLPTVSHSGFLYKTASAGKLLQDRRAREEFSRRWCVLGDGVLSYFENERAVTPNGEIRASE IVCLAVPPPDTHGFEHTFEVYTEGERLYLFGLESAEQAHEWVKCIAKAFVPPLAEDLLARDFERLGRLPYKAGLSLQRAQEGWFSLSGSE LRAVFPEGPCEEPLQLRKLQELSIQGDSENQVLVLVERRRTLYIQGERRLDFMGWLGAIQKAAASMGDTLSEQQLGDSDIPVIVYRCVDY ITQCGLTSEGIYRKCGQTSKTQRLLESLRQDARSVHLKEGEQHVDDVSSALKRFLRDLPDGLFTRAQRLTWLEASEIEDEEEKVSRYREL LVRLPPVNRATVKALISHLYCVQCFSDTNQMNVHNLAIVFGPTLFQTDGQDYKAGRVVEDLINHYVVVFSVDEEELRKQREEITAIVKMR VAGTASGTQHAGDFICTVYLEEKKAETEQHIKVPASMTAEELTLEILDRRNVGIREKDYWTCFEVNEREEAERPLHFAEKVLPILHGLGT DSHLVVKKHQAMEAMLLYLASRVGDTKHGMMKFREDRSLLGLGLPSGGFHDRYFILNSSCLRLYKEVRNLSVSEARGKILHYQVTLQELT GGKAMTQNITGHTSWTTVIPRTGNWAVAVSAANSKGSSLPTRINIMNLCEAGLLAPRQVSANSEGMDNILVTWQPPRKDPSAVQEYVVEW RELHPGGDTQVPLNWLRSRPYNVSALISENIKSYICYEIRVYALSGDQGGCSSILGNSKHKAPLSGPHINAITEEKGSILISWNSIPVQE QMGCLLHYRIYWKERDSNSQPQLCEIPYRVSQNSHPINSLQPRVTYVLWMTALTAAGESSHGNEREFCLQGKANWMAFVAPSICIAIIMV GIFSTHYFQQKVFVLLAALRPQWCSREIPDPANSTCAKKYPIAEEKTQLPLDRLLIDWPTPEDPEPLVISEVLHQVTPVFRHPPCSNWPQ REKGIQGHQASEKDMMHSASSPPPPRALQAESRQLVDLYKVLESRGSDPKPENPACPWTVLPAGDLPTHDGYLPSNIDDLPSHEAPLADS -------------------------------------------------------------- >5760_5760_26_ARAP1-IL12RB2_ARAP1_chr11_72404370_ENST00000334211_IL12RB2_chr1_67816553_ENST00000371000_length(amino acids)=1461AA_BP=1148 MPTKEEESLLPSLSSPPQPQSEEPLSTLPQGPPQPPSPPPCPPEIPPKPVRLFPEFDDSDYDEVPEEGPGAPARVMTKKEEPPPSRVPRA VRVASLLSEGEELSGDDQGDEEEDDHAYEGVPNGGWHTSSLSLSLPSTIAAPHPMDGPPGGSTPVTPVIKAGWLDKNPPQGSYIYQKRWV RLDTDHLRYFDSNKDAYSKRFISVACISHVAAIGDQKFEVITNNRTFAFRAESDVERKEWMQALQQAMAEQRARARLSSAYLLGVPGSEQ PDRAGSLELRGFKNKLYVAVVGDKVQLYKNLEEYHLGIGITFIDMSVGNVKEVDRRSFDLTTPYRIFSFSADSELEKEQWLEAMQGAIAE ALSTSEVAERIWAAAPNRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTETLIELFLQLGNGAGNRFWAAN VPPSEALQPSSSPSTRRCHLEAKYREGKYRRYHPLFGNQEELDKALCAAVTTTDLAETQALLGCGAGINCFSGDPEAPTPLALAEQAGQT LQMEFLRNNRTTEVPRLDSMKPLEKHYSVVLPTVSHSGFLYKTASAGKLLQDRRAREEFSRRWCVLGDGVLSYFENERAVTPNGEIRASE IVCLAVPPPDTHGFEHTFEVYTEGERLYLFGLESAEQAHEWVKCIAKAFVPPLAEDLLARDFERLGRLPYKAGLSLQRAQEGWFSLSGSE LRAVFPEGPCEEPLQLRKLQELSIQGDSENQVLVLVERRRTLYIQGERRLDFMGWLGAIQKAAASMGDTLSEQQLGDSDIPVIVYRCVDY ITQCGLTSEGIYRKCGQTSKTQRLLESLRQDARSVHLKEGEQHVDDVSSALKRFLRDLPDGLFTRAQRLTWLEASEIEDEEEKVSRYREL LVRLPPVNRATVKALISHLYCVQCFSDTNQMNVHNLAIVFGPTLFQTDGQDYKAGRVVEDLINHYVVVFSVDEEELRKQREEITAIVKMR VAGTASGTQHAGDFICTVYLEEKKAETEQHIKVPASMTAEELTLEILDRRNVGIREKDYWTCFEVNEREEAERPLHFAEKVLPILHGLGT DSHLVVKKHQAMEAMLLYLASRVGDTKHGMMKFREDRSLLGLGLPSGGFHDRYFILNSSCLRLYKEVRNLSVSEARGKILHYQVTLQELT GGKAMTQNITGHTSWTTVIPRTGNWAVAVSAANSKGSSLPTRINIMNLCEAGLLAPRQVSANSEGMDNILVTWQPPRKDPSAVQEYVVEW RELHPGGDTQVPLNWLRSRPYNVSALISENIKSYICYEIRVYALSGDQGGCSSILGNSKHKAPLSGPHINAITEEKGSILISWNSIPVQE QMGCLLHYRIYWKERDSNSQPQLCEIPYRVSQNSHPINSLQPRVTYVLWMTALTAAGESSHGNEREFCLQGKANWMAFVAPSICIAIIMV -------------------------------------------------------------- >5760_5760_27_ARAP1-IL12RB2_ARAP1_chr11_72404370_ENST00000334211_IL12RB2_chr1_67816553_ENST00000541374_length(amino acids)=1461AA_BP=1148 MPTKEEESLLPSLSSPPQPQSEEPLSTLPQGPPQPPSPPPCPPEIPPKPVRLFPEFDDSDYDEVPEEGPGAPARVMTKKEEPPPSRVPRA VRVASLLSEGEELSGDDQGDEEEDDHAYEGVPNGGWHTSSLSLSLPSTIAAPHPMDGPPGGSTPVTPVIKAGWLDKNPPQGSYIYQKRWV RLDTDHLRYFDSNKDAYSKRFISVACISHVAAIGDQKFEVITNNRTFAFRAESDVERKEWMQALQQAMAEQRARARLSSAYLLGVPGSEQ PDRAGSLELRGFKNKLYVAVVGDKVQLYKNLEEYHLGIGITFIDMSVGNVKEVDRRSFDLTTPYRIFSFSADSELEKEQWLEAMQGAIAE ALSTSEVAERIWAAAPNRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTETLIELFLQLGNGAGNRFWAAN VPPSEALQPSSSPSTRRCHLEAKYREGKYRRYHPLFGNQEELDKALCAAVTTTDLAETQALLGCGAGINCFSGDPEAPTPLALAEQAGQT LQMEFLRNNRTTEVPRLDSMKPLEKHYSVVLPTVSHSGFLYKTASAGKLLQDRRAREEFSRRWCVLGDGVLSYFENERAVTPNGEIRASE IVCLAVPPPDTHGFEHTFEVYTEGERLYLFGLESAEQAHEWVKCIAKAFVPPLAEDLLARDFERLGRLPYKAGLSLQRAQEGWFSLSGSE LRAVFPEGPCEEPLQLRKLQELSIQGDSENQVLVLVERRRTLYIQGERRLDFMGWLGAIQKAAASMGDTLSEQQLGDSDIPVIVYRCVDY ITQCGLTSEGIYRKCGQTSKTQRLLESLRQDARSVHLKEGEQHVDDVSSALKRFLRDLPDGLFTRAQRLTWLEASEIEDEEEKVSRYREL LVRLPPVNRATVKALISHLYCVQCFSDTNQMNVHNLAIVFGPTLFQTDGQDYKAGRVVEDLINHYVVVFSVDEEELRKQREEITAIVKMR VAGTASGTQHAGDFICTVYLEEKKAETEQHIKVPASMTAEELTLEILDRRNVGIREKDYWTCFEVNEREEAERPLHFAEKVLPILHGLGT DSHLVVKKHQAMEAMLLYLASRVGDTKHGMMKFREDRSLLGLGLPSGGFHDRYFILNSSCLRLYKEVRNLSVSEARGKILHYQVTLQELT GGKAMTQNITGHTSWTTVIPRTGNWAVAVSAANSKGSSLPTRINIMNLCEAGLLAPRQVSANSEGMDNILVTWQPPRKDPSAVQEYVVEW RELHPGGDTQVPLNWLRSRPYNVSALISENIKSYICYEIRVYALSGDQGGCSSILGNSKHKAPLSGPHINAITEEKGSILISWNSIPVQE QMGCLLHYRIYWKERDSNSQPQLCEIPYRVSQNSHPINSLQPRVTYVLWMTALTAAGESSHGNEREFCLQGKANWMAFVAPSICIAIIMV -------------------------------------------------------------- >5760_5760_28_ARAP1-IL12RB2_ARAP1_chr11_72404370_ENST00000334211_IL12RB2_chr1_67816553_ENST00000544434_length(amino acids)=1578AA_BP=1148 MPTKEEESLLPSLSSPPQPQSEEPLSTLPQGPPQPPSPPPCPPEIPPKPVRLFPEFDDSDYDEVPEEGPGAPARVMTKKEEPPPSRVPRA VRVASLLSEGEELSGDDQGDEEEDDHAYEGVPNGGWHTSSLSLSLPSTIAAPHPMDGPPGGSTPVTPVIKAGWLDKNPPQGSYIYQKRWV RLDTDHLRYFDSNKDAYSKRFISVACISHVAAIGDQKFEVITNNRTFAFRAESDVERKEWMQALQQAMAEQRARARLSSAYLLGVPGSEQ PDRAGSLELRGFKNKLYVAVVGDKVQLYKNLEEYHLGIGITFIDMSVGNVKEVDRRSFDLTTPYRIFSFSADSELEKEQWLEAMQGAIAE ALSTSEVAERIWAAAPNRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTETLIELFLQLGNGAGNRFWAAN VPPSEALQPSSSPSTRRCHLEAKYREGKYRRYHPLFGNQEELDKALCAAVTTTDLAETQALLGCGAGINCFSGDPEAPTPLALAEQAGQT LQMEFLRNNRTTEVPRLDSMKPLEKHYSVVLPTVSHSGFLYKTASAGKLLQDRRAREEFSRRWCVLGDGVLSYFENERAVTPNGEIRASE IVCLAVPPPDTHGFEHTFEVYTEGERLYLFGLESAEQAHEWVKCIAKAFVPPLAEDLLARDFERLGRLPYKAGLSLQRAQEGWFSLSGSE LRAVFPEGPCEEPLQLRKLQELSIQGDSENQVLVLVERRRTLYIQGERRLDFMGWLGAIQKAAASMGDTLSEQQLGDSDIPVIVYRCVDY ITQCGLTSEGIYRKCGQTSKTQRLLESLRQDARSVHLKEGEQHVDDVSSALKRFLRDLPDGLFTRAQRLTWLEASEIEDEEEKVSRYREL LVRLPPVNRATVKALISHLYCVQCFSDTNQMNVHNLAIVFGPTLFQTDGQDYKAGRVVEDLINHYVVVFSVDEEELRKQREEITAIVKMR VAGTASGTQHAGDFICTVYLEEKKAETEQHIKVPASMTAEELTLEILDRRNVGIREKDYWTCFEVNEREEAERPLHFAEKVLPILHGLGT DSHLVVKKHQAMEAMLLYLASRVGDTKHGMMKFREDRSLLGLGLPSGGFHDRYFILNSSCLRLYKEVRNLSVSEARGKILHYQVTLQELT GGKAMTQNITGHTSWTTVIPRTGNWAVAVSAANSKGSSLPTRINIMNLCEAGLLAPRQVSANSEGMDNILVTWQPPRKDPSAVQEYVVEW RELHPGGDTQVPLNWLRSRPYNVSALISEIPYRVSQNSHPINSLQPRVTYVLWMTALTAAGESSHGNEREFCLQGKANWMAFVAPSICIA IIMVGIFSTHYFQQKVFVLLAALRPQWCSREIPDPANSTCAKKYPIAEEKTQLPLDRLLIDWPTPEDPEPLVISEVLHQVTPVFRHPPCS NWPQREKGIQGHQASEKDMMHSASSPPPPRALQAESRQLVDLYKVLESRGSDPKPENPACPWTVLPAGDLPTHDGYLPSNIDDLPSHEAP -------------------------------------------------------------- >5760_5760_29_ARAP1-IL12RB2_ARAP1_chr11_72404370_ENST00000359373_IL12RB2_chr1_67816553_ENST00000262345_length(amino acids)=1848AA_BP=1332 MDKALPVRPPLAGTMAEAGDAALSVAEWLRALHLEQYTGLFEQHGLVWATECQGLSDTRLMDMGMLLPGHRRRILAGLLRAHTSPAPAPR PTPRPVPMKRHIFRSPPVPATPPEPLPTTTEDEGLPAAPPIPPRRSCLPPTCFTTPSTAAPDPVLPPLPAKRHLAELSVPPVPPRTGPPR LLVSLPTKEEESLLPSLSSPPQPQSEEPLSTLPQGPPQPPSPPPCPPEIPPKPVRLFPEFDDSDYDEVPEEGPGAPARVMTKKEEPPPSR VPRAVRVASLLSEGEELSGDDQGDEEEDDHAYEGVPNGGWHTSSLSLSLPSTIAAPHPMDGPPGGSTPVTPVIKAGWLDKNPPQGSYIYQ KRWVRLDTDHLRYFDSNKDAYSKRFISVACISHVAAIGDQKFEVITNNRTFAFRAESDVERKEWMQALQQAMAEQRARARLSSAYLLGVP GSEQPDRAGSLELRGFKNKLYVAVVGDKVQLYKNLEEYHLGIGITFIDMSVGNVKEVDRRSFDLTTPYRIFSFSADSELEKEQWLEAMQG AIAEALSTSEVAERIWAAAPNRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTETLIELFLQLGNGAGNRF WAANVPPSEALQPSSSPSTRRCHLEAKYREGKYRRYHPLFGNQEELDKALCAAVTTTDLAETQALLGCGAGINCFSGDPEAPTPLALAEQ AGQTLQMEFLRNNRTTEVPRLDSMKPLEKHYSVVLPTVSHSGFLYKTASAGKLLQDRRAREEFSRRWCVLGDGVLSYFENERAVTPNGEI RASEIVCLAVPPPDTHGFEHTFEVYTEGERLYLFGLESAEQAHEWVKCIAKAFVPPLAEDLLARDFERLGRLPYKAGLSLQRAQEGWFSL SGSELRAVFPEGPCEEPLQLRKLQELSIQGDSENQVLVLVERRRTLYIQGERRLDFMGWLGAIQKAAASMGDTLSEQQLGDSDIPVIVYR CVDYITQCGLTSEGIYRKCGQTSKTQRLLESLRQDARSVHLKEGEQHVDDVSSALKRFLRDLPDGLFTRAQRLTWLEASEIEDEEEKVSR YRELLVRLPPVNRATVKALISHLYCVQCFSDTNQMNVHNLAIVFGPTLFQTDGQDYKAGRVVEDLINHYVVVFSVDEEELRKQREEITAI VKMRVAGTASGTQHAGDFICTVYLEEKKAETEQHIKVPASMTAEELTLEILDRRNVGIREKDYWTCFEVNEREEAERPLHFAEKVLPILH GLGTDSHLVVKKHQAMEAMLLYLASRVGDTKHGMMKFREDRSLLGLGLPSGGFHDRYFILNSSCLRLYKEVRNLSVSEARGKILHYQVTL QELTGGKAMTQNITGHTSWTTVIPRTGNWAVAVSAANSKGSSLPTRINIMNLCEAGLLAPRQVSANSEGMDNILVTWQPPRKDPSAVQEY VVEWRELHPGGDTQVPLNWLRSRPYNVSALISENIKSYICYEIRVYALSGDQGGCSSILGNSKHKAPLSGPHINAITEEKGSILISWNSI PVQEQMGCLLHYRIYWKERDSNSQPQLCEIPYRVSQNSHPINSLQPRVTYVLWMTALTAAGESSHGNEREFCLQGKANWMAFVAPSICIA IIMVGIFSTHYFQQKVFVLLAALRPQWCSREIPDPANSTCAKKYPIAEEKTQLPLDRLLIDWPTPEDPEPLVISEVLHQVTPVFRHPPCS NWPQREKGIQGHQASEKDMMHSASSPPPPRALQAESRQLVDLYKVLESRGSDPKPENPACPWTVLPAGDLPTHDGYLPSNIDDLPSHEAP -------------------------------------------------------------- >5760_5760_30_ARAP1-IL12RB2_ARAP1_chr11_72404370_ENST00000359373_IL12RB2_chr1_67816553_ENST00000371000_length(amino acids)=1645AA_BP=1332 MDKALPVRPPLAGTMAEAGDAALSVAEWLRALHLEQYTGLFEQHGLVWATECQGLSDTRLMDMGMLLPGHRRRILAGLLRAHTSPAPAPR PTPRPVPMKRHIFRSPPVPATPPEPLPTTTEDEGLPAAPPIPPRRSCLPPTCFTTPSTAAPDPVLPPLPAKRHLAELSVPPVPPRTGPPR LLVSLPTKEEESLLPSLSSPPQPQSEEPLSTLPQGPPQPPSPPPCPPEIPPKPVRLFPEFDDSDYDEVPEEGPGAPARVMTKKEEPPPSR VPRAVRVASLLSEGEELSGDDQGDEEEDDHAYEGVPNGGWHTSSLSLSLPSTIAAPHPMDGPPGGSTPVTPVIKAGWLDKNPPQGSYIYQ KRWVRLDTDHLRYFDSNKDAYSKRFISVACISHVAAIGDQKFEVITNNRTFAFRAESDVERKEWMQALQQAMAEQRARARLSSAYLLGVP GSEQPDRAGSLELRGFKNKLYVAVVGDKVQLYKNLEEYHLGIGITFIDMSVGNVKEVDRRSFDLTTPYRIFSFSADSELEKEQWLEAMQG AIAEALSTSEVAERIWAAAPNRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTETLIELFLQLGNGAGNRF WAANVPPSEALQPSSSPSTRRCHLEAKYREGKYRRYHPLFGNQEELDKALCAAVTTTDLAETQALLGCGAGINCFSGDPEAPTPLALAEQ AGQTLQMEFLRNNRTTEVPRLDSMKPLEKHYSVVLPTVSHSGFLYKTASAGKLLQDRRAREEFSRRWCVLGDGVLSYFENERAVTPNGEI RASEIVCLAVPPPDTHGFEHTFEVYTEGERLYLFGLESAEQAHEWVKCIAKAFVPPLAEDLLARDFERLGRLPYKAGLSLQRAQEGWFSL SGSELRAVFPEGPCEEPLQLRKLQELSIQGDSENQVLVLVERRRTLYIQGERRLDFMGWLGAIQKAAASMGDTLSEQQLGDSDIPVIVYR CVDYITQCGLTSEGIYRKCGQTSKTQRLLESLRQDARSVHLKEGEQHVDDVSSALKRFLRDLPDGLFTRAQRLTWLEASEIEDEEEKVSR YRELLVRLPPVNRATVKALISHLYCVQCFSDTNQMNVHNLAIVFGPTLFQTDGQDYKAGRVVEDLINHYVVVFSVDEEELRKQREEITAI VKMRVAGTASGTQHAGDFICTVYLEEKKAETEQHIKVPASMTAEELTLEILDRRNVGIREKDYWTCFEVNEREEAERPLHFAEKVLPILH GLGTDSHLVVKKHQAMEAMLLYLASRVGDTKHGMMKFREDRSLLGLGLPSGGFHDRYFILNSSCLRLYKEVRNLSVSEARGKILHYQVTL QELTGGKAMTQNITGHTSWTTVIPRTGNWAVAVSAANSKGSSLPTRINIMNLCEAGLLAPRQVSANSEGMDNILVTWQPPRKDPSAVQEY VVEWRELHPGGDTQVPLNWLRSRPYNVSALISENIKSYICYEIRVYALSGDQGGCSSILGNSKHKAPLSGPHINAITEEKGSILISWNSI PVQEQMGCLLHYRIYWKERDSNSQPQLCEIPYRVSQNSHPINSLQPRVTYVLWMTALTAAGESSHGNEREFCLQGKANWMAFVAPSICIA -------------------------------------------------------------- >5760_5760_31_ARAP1-IL12RB2_ARAP1_chr11_72404370_ENST00000359373_IL12RB2_chr1_67816553_ENST00000541374_length(amino acids)=1645AA_BP=1332 MDKALPVRPPLAGTMAEAGDAALSVAEWLRALHLEQYTGLFEQHGLVWATECQGLSDTRLMDMGMLLPGHRRRILAGLLRAHTSPAPAPR PTPRPVPMKRHIFRSPPVPATPPEPLPTTTEDEGLPAAPPIPPRRSCLPPTCFTTPSTAAPDPVLPPLPAKRHLAELSVPPVPPRTGPPR LLVSLPTKEEESLLPSLSSPPQPQSEEPLSTLPQGPPQPPSPPPCPPEIPPKPVRLFPEFDDSDYDEVPEEGPGAPARVMTKKEEPPPSR VPRAVRVASLLSEGEELSGDDQGDEEEDDHAYEGVPNGGWHTSSLSLSLPSTIAAPHPMDGPPGGSTPVTPVIKAGWLDKNPPQGSYIYQ KRWVRLDTDHLRYFDSNKDAYSKRFISVACISHVAAIGDQKFEVITNNRTFAFRAESDVERKEWMQALQQAMAEQRARARLSSAYLLGVP GSEQPDRAGSLELRGFKNKLYVAVVGDKVQLYKNLEEYHLGIGITFIDMSVGNVKEVDRRSFDLTTPYRIFSFSADSELEKEQWLEAMQG AIAEALSTSEVAERIWAAAPNRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTETLIELFLQLGNGAGNRF WAANVPPSEALQPSSSPSTRRCHLEAKYREGKYRRYHPLFGNQEELDKALCAAVTTTDLAETQALLGCGAGINCFSGDPEAPTPLALAEQ AGQTLQMEFLRNNRTTEVPRLDSMKPLEKHYSVVLPTVSHSGFLYKTASAGKLLQDRRAREEFSRRWCVLGDGVLSYFENERAVTPNGEI RASEIVCLAVPPPDTHGFEHTFEVYTEGERLYLFGLESAEQAHEWVKCIAKAFVPPLAEDLLARDFERLGRLPYKAGLSLQRAQEGWFSL SGSELRAVFPEGPCEEPLQLRKLQELSIQGDSENQVLVLVERRRTLYIQGERRLDFMGWLGAIQKAAASMGDTLSEQQLGDSDIPVIVYR CVDYITQCGLTSEGIYRKCGQTSKTQRLLESLRQDARSVHLKEGEQHVDDVSSALKRFLRDLPDGLFTRAQRLTWLEASEIEDEEEKVSR YRELLVRLPPVNRATVKALISHLYCVQCFSDTNQMNVHNLAIVFGPTLFQTDGQDYKAGRVVEDLINHYVVVFSVDEEELRKQREEITAI VKMRVAGTASGTQHAGDFICTVYLEEKKAETEQHIKVPASMTAEELTLEILDRRNVGIREKDYWTCFEVNEREEAERPLHFAEKVLPILH GLGTDSHLVVKKHQAMEAMLLYLASRVGDTKHGMMKFREDRSLLGLGLPSGGFHDRYFILNSSCLRLYKEVRNLSVSEARGKILHYQVTL QELTGGKAMTQNITGHTSWTTVIPRTGNWAVAVSAANSKGSSLPTRINIMNLCEAGLLAPRQVSANSEGMDNILVTWQPPRKDPSAVQEY VVEWRELHPGGDTQVPLNWLRSRPYNVSALISENIKSYICYEIRVYALSGDQGGCSSILGNSKHKAPLSGPHINAITEEKGSILISWNSI PVQEQMGCLLHYRIYWKERDSNSQPQLCEIPYRVSQNSHPINSLQPRVTYVLWMTALTAAGESSHGNEREFCLQGKANWMAFVAPSICIA -------------------------------------------------------------- >5760_5760_32_ARAP1-IL12RB2_ARAP1_chr11_72404370_ENST00000359373_IL12RB2_chr1_67816553_ENST00000544434_length(amino acids)=1762AA_BP=1332 MDKALPVRPPLAGTMAEAGDAALSVAEWLRALHLEQYTGLFEQHGLVWATECQGLSDTRLMDMGMLLPGHRRRILAGLLRAHTSPAPAPR PTPRPVPMKRHIFRSPPVPATPPEPLPTTTEDEGLPAAPPIPPRRSCLPPTCFTTPSTAAPDPVLPPLPAKRHLAELSVPPVPPRTGPPR LLVSLPTKEEESLLPSLSSPPQPQSEEPLSTLPQGPPQPPSPPPCPPEIPPKPVRLFPEFDDSDYDEVPEEGPGAPARVMTKKEEPPPSR VPRAVRVASLLSEGEELSGDDQGDEEEDDHAYEGVPNGGWHTSSLSLSLPSTIAAPHPMDGPPGGSTPVTPVIKAGWLDKNPPQGSYIYQ KRWVRLDTDHLRYFDSNKDAYSKRFISVACISHVAAIGDQKFEVITNNRTFAFRAESDVERKEWMQALQQAMAEQRARARLSSAYLLGVP GSEQPDRAGSLELRGFKNKLYVAVVGDKVQLYKNLEEYHLGIGITFIDMSVGNVKEVDRRSFDLTTPYRIFSFSADSELEKEQWLEAMQG AIAEALSTSEVAERIWAAAPNRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTETLIELFLQLGNGAGNRF WAANVPPSEALQPSSSPSTRRCHLEAKYREGKYRRYHPLFGNQEELDKALCAAVTTTDLAETQALLGCGAGINCFSGDPEAPTPLALAEQ AGQTLQMEFLRNNRTTEVPRLDSMKPLEKHYSVVLPTVSHSGFLYKTASAGKLLQDRRAREEFSRRWCVLGDGVLSYFENERAVTPNGEI RASEIVCLAVPPPDTHGFEHTFEVYTEGERLYLFGLESAEQAHEWVKCIAKAFVPPLAEDLLARDFERLGRLPYKAGLSLQRAQEGWFSL SGSELRAVFPEGPCEEPLQLRKLQELSIQGDSENQVLVLVERRRTLYIQGERRLDFMGWLGAIQKAAASMGDTLSEQQLGDSDIPVIVYR CVDYITQCGLTSEGIYRKCGQTSKTQRLLESLRQDARSVHLKEGEQHVDDVSSALKRFLRDLPDGLFTRAQRLTWLEASEIEDEEEKVSR YRELLVRLPPVNRATVKALISHLYCVQCFSDTNQMNVHNLAIVFGPTLFQTDGQDYKAGRVVEDLINHYVVVFSVDEEELRKQREEITAI VKMRVAGTASGTQHAGDFICTVYLEEKKAETEQHIKVPASMTAEELTLEILDRRNVGIREKDYWTCFEVNEREEAERPLHFAEKVLPILH GLGTDSHLVVKKHQAMEAMLLYLASRVGDTKHGMMKFREDRSLLGLGLPSGGFHDRYFILNSSCLRLYKEVRNLSVSEARGKILHYQVTL QELTGGKAMTQNITGHTSWTTVIPRTGNWAVAVSAANSKGSSLPTRINIMNLCEAGLLAPRQVSANSEGMDNILVTWQPPRKDPSAVQEY VVEWRELHPGGDTQVPLNWLRSRPYNVSALISEIPYRVSQNSHPINSLQPRVTYVLWMTALTAAGESSHGNEREFCLQGKANWMAFVAPS ICIAIIMVGIFSTHYFQQKVFVLLAALRPQWCSREIPDPANSTCAKKYPIAEEKTQLPLDRLLIDWPTPEDPEPLVISEVLHQVTPVFRH PPCSNWPQREKGIQGHQASEKDMMHSASSPPPPRALQAESRQLVDLYKVLESRGSDPKPENPACPWTVLPAGDLPTHDGYLPSNIDDLPS -------------------------------------------------------------- >5760_5760_33_ARAP1-IL12RB2_ARAP1_chr11_72404370_ENST00000393605_IL12RB2_chr1_67816553_ENST00000262345_length(amino acids)=1598AA_BP=1082 MKGRMTLSGSRGQEEPPPSRVPRAVRVASLLSEGEELSGDDQGDEEEDDHAYEGVPNGGWHTSSLSLSLPSTIAAPHPMDGPPGGSTPVT PVIKAGWLDKNPPQGSYIYQKRWVRLDTDHLRYFDSNKDAYSKRFISVACISHVAAIGDQKFEVITNNRTFAFRAESDVERKEWMQALQQ AMAEQRARARLSSAYLLGVPGSEQPDRAGSLELRGFKNKLYVAVVGDKVQLYKNLEEYHLGIGITFIDMSVGNVKEVDRRSFDLTTPYRI FSFSADSELEKEQWLEAMQGAIAEALSTSEVAERIWAAAPNRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKV WTETLIELFLQLGNGAGNRFWAANVPPSEALQPSSSPSTRRCHLEAKYREGKYRRYHPLFGNQEELDKALCAAVTTTDLAETQALLGCGA GINCFSGDPEAPTPLALAEQAGQTLQMEFLRNNRTTEVPRLDSMKPLEKHYSVVLPTVSHSGFLYKTASAGKLLQDRRAREEFSRRWCVL GDGVLSYFENERAVTPNGEIRASEIVCLAVPPPDTHGFEHTFEVYTEGERLYLFGLESAEQAHEWVKCIAKAFVPPLAEDLLARDFERLG RLPYKAGLSLQRAQEGWFSLSGSELRAVFPEGPCEEPLQLRKLQELSIQGDSENQVLVLVERRRTLYIQGERRLDFMGWLGAIQKAAASM GDTLSEQQLGDSDIPVIVYRCVDYITQCGLTSEGIYRKCGQTSKTQRLLESLRQDARSVHLKEGEQHVDDVSSALKRFLRDLPDGLFTRA QRLTWLEASEIEDEEEKVSRYRELLVRLPPVNRATVKALISHLYCVQCFSDTNQMNVHNLAIVFGPTLFQTDGQDYKAGRVVEDLINHYV VVFSVDEEELRKQREEITAIVKMRVAGTASGTQHAGDFICTVYLEEKKAETEQHIKVPASMTAEELTLEILDRRNVGIREKDYWTCFEVN EREEAERPLHFAEKVLPILHGLGTDSHLVVKKHQAMEAMLLYLASRVGDTKHGMMKFREDRSLLGLGLPSGGFHDRYFILNSSCLRLYKE VRNLSVSEARGKILHYQVTLQELTGGKAMTQNITGHTSWTTVIPRTGNWAVAVSAANSKGSSLPTRINIMNLCEAGLLAPRQVSANSEGM DNILVTWQPPRKDPSAVQEYVVEWRELHPGGDTQVPLNWLRSRPYNVSALISENIKSYICYEIRVYALSGDQGGCSSILGNSKHKAPLSG PHINAITEEKGSILISWNSIPVQEQMGCLLHYRIYWKERDSNSQPQLCEIPYRVSQNSHPINSLQPRVTYVLWMTALTAAGESSHGNERE FCLQGKANWMAFVAPSICIAIIMVGIFSTHYFQQKVFVLLAALRPQWCSREIPDPANSTCAKKYPIAEEKTQLPLDRLLIDWPTPEDPEP LVISEVLHQVTPVFRHPPCSNWPQREKGIQGHQASEKDMMHSASSPPPPRALQAESRQLVDLYKVLESRGSDPKPENPACPWTVLPAGDL -------------------------------------------------------------- >5760_5760_34_ARAP1-IL12RB2_ARAP1_chr11_72404370_ENST00000393605_IL12RB2_chr1_67816553_ENST00000371000_length(amino acids)=1395AA_BP=1082 MKGRMTLSGSRGQEEPPPSRVPRAVRVASLLSEGEELSGDDQGDEEEDDHAYEGVPNGGWHTSSLSLSLPSTIAAPHPMDGPPGGSTPVT PVIKAGWLDKNPPQGSYIYQKRWVRLDTDHLRYFDSNKDAYSKRFISVACISHVAAIGDQKFEVITNNRTFAFRAESDVERKEWMQALQQ AMAEQRARARLSSAYLLGVPGSEQPDRAGSLELRGFKNKLYVAVVGDKVQLYKNLEEYHLGIGITFIDMSVGNVKEVDRRSFDLTTPYRI FSFSADSELEKEQWLEAMQGAIAEALSTSEVAERIWAAAPNRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKV WTETLIELFLQLGNGAGNRFWAANVPPSEALQPSSSPSTRRCHLEAKYREGKYRRYHPLFGNQEELDKALCAAVTTTDLAETQALLGCGA GINCFSGDPEAPTPLALAEQAGQTLQMEFLRNNRTTEVPRLDSMKPLEKHYSVVLPTVSHSGFLYKTASAGKLLQDRRAREEFSRRWCVL GDGVLSYFENERAVTPNGEIRASEIVCLAVPPPDTHGFEHTFEVYTEGERLYLFGLESAEQAHEWVKCIAKAFVPPLAEDLLARDFERLG RLPYKAGLSLQRAQEGWFSLSGSELRAVFPEGPCEEPLQLRKLQELSIQGDSENQVLVLVERRRTLYIQGERRLDFMGWLGAIQKAAASM GDTLSEQQLGDSDIPVIVYRCVDYITQCGLTSEGIYRKCGQTSKTQRLLESLRQDARSVHLKEGEQHVDDVSSALKRFLRDLPDGLFTRA QRLTWLEASEIEDEEEKVSRYRELLVRLPPVNRATVKALISHLYCVQCFSDTNQMNVHNLAIVFGPTLFQTDGQDYKAGRVVEDLINHYV VVFSVDEEELRKQREEITAIVKMRVAGTASGTQHAGDFICTVYLEEKKAETEQHIKVPASMTAEELTLEILDRRNVGIREKDYWTCFEVN EREEAERPLHFAEKVLPILHGLGTDSHLVVKKHQAMEAMLLYLASRVGDTKHGMMKFREDRSLLGLGLPSGGFHDRYFILNSSCLRLYKE VRNLSVSEARGKILHYQVTLQELTGGKAMTQNITGHTSWTTVIPRTGNWAVAVSAANSKGSSLPTRINIMNLCEAGLLAPRQVSANSEGM DNILVTWQPPRKDPSAVQEYVVEWRELHPGGDTQVPLNWLRSRPYNVSALISENIKSYICYEIRVYALSGDQGGCSSILGNSKHKAPLSG PHINAITEEKGSILISWNSIPVQEQMGCLLHYRIYWKERDSNSQPQLCEIPYRVSQNSHPINSLQPRVTYVLWMTALTAAGESSHGNERE -------------------------------------------------------------- >5760_5760_35_ARAP1-IL12RB2_ARAP1_chr11_72404370_ENST00000393605_IL12RB2_chr1_67816553_ENST00000541374_length(amino acids)=1395AA_BP=1082 MKGRMTLSGSRGQEEPPPSRVPRAVRVASLLSEGEELSGDDQGDEEEDDHAYEGVPNGGWHTSSLSLSLPSTIAAPHPMDGPPGGSTPVT PVIKAGWLDKNPPQGSYIYQKRWVRLDTDHLRYFDSNKDAYSKRFISVACISHVAAIGDQKFEVITNNRTFAFRAESDVERKEWMQALQQ AMAEQRARARLSSAYLLGVPGSEQPDRAGSLELRGFKNKLYVAVVGDKVQLYKNLEEYHLGIGITFIDMSVGNVKEVDRRSFDLTTPYRI FSFSADSELEKEQWLEAMQGAIAEALSTSEVAERIWAAAPNRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKV WTETLIELFLQLGNGAGNRFWAANVPPSEALQPSSSPSTRRCHLEAKYREGKYRRYHPLFGNQEELDKALCAAVTTTDLAETQALLGCGA GINCFSGDPEAPTPLALAEQAGQTLQMEFLRNNRTTEVPRLDSMKPLEKHYSVVLPTVSHSGFLYKTASAGKLLQDRRAREEFSRRWCVL GDGVLSYFENERAVTPNGEIRASEIVCLAVPPPDTHGFEHTFEVYTEGERLYLFGLESAEQAHEWVKCIAKAFVPPLAEDLLARDFERLG RLPYKAGLSLQRAQEGWFSLSGSELRAVFPEGPCEEPLQLRKLQELSIQGDSENQVLVLVERRRTLYIQGERRLDFMGWLGAIQKAAASM GDTLSEQQLGDSDIPVIVYRCVDYITQCGLTSEGIYRKCGQTSKTQRLLESLRQDARSVHLKEGEQHVDDVSSALKRFLRDLPDGLFTRA QRLTWLEASEIEDEEEKVSRYRELLVRLPPVNRATVKALISHLYCVQCFSDTNQMNVHNLAIVFGPTLFQTDGQDYKAGRVVEDLINHYV VVFSVDEEELRKQREEITAIVKMRVAGTASGTQHAGDFICTVYLEEKKAETEQHIKVPASMTAEELTLEILDRRNVGIREKDYWTCFEVN EREEAERPLHFAEKVLPILHGLGTDSHLVVKKHQAMEAMLLYLASRVGDTKHGMMKFREDRSLLGLGLPSGGFHDRYFILNSSCLRLYKE VRNLSVSEARGKILHYQVTLQELTGGKAMTQNITGHTSWTTVIPRTGNWAVAVSAANSKGSSLPTRINIMNLCEAGLLAPRQVSANSEGM DNILVTWQPPRKDPSAVQEYVVEWRELHPGGDTQVPLNWLRSRPYNVSALISENIKSYICYEIRVYALSGDQGGCSSILGNSKHKAPLSG PHINAITEEKGSILISWNSIPVQEQMGCLLHYRIYWKERDSNSQPQLCEIPYRVSQNSHPINSLQPRVTYVLWMTALTAAGESSHGNERE -------------------------------------------------------------- >5760_5760_36_ARAP1-IL12RB2_ARAP1_chr11_72404370_ENST00000393605_IL12RB2_chr1_67816553_ENST00000544434_length(amino acids)=1512AA_BP=1082 MKGRMTLSGSRGQEEPPPSRVPRAVRVASLLSEGEELSGDDQGDEEEDDHAYEGVPNGGWHTSSLSLSLPSTIAAPHPMDGPPGGSTPVT PVIKAGWLDKNPPQGSYIYQKRWVRLDTDHLRYFDSNKDAYSKRFISVACISHVAAIGDQKFEVITNNRTFAFRAESDVERKEWMQALQQ AMAEQRARARLSSAYLLGVPGSEQPDRAGSLELRGFKNKLYVAVVGDKVQLYKNLEEYHLGIGITFIDMSVGNVKEVDRRSFDLTTPYRI FSFSADSELEKEQWLEAMQGAIAEALSTSEVAERIWAAAPNRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKV WTETLIELFLQLGNGAGNRFWAANVPPSEALQPSSSPSTRRCHLEAKYREGKYRRYHPLFGNQEELDKALCAAVTTTDLAETQALLGCGA GINCFSGDPEAPTPLALAEQAGQTLQMEFLRNNRTTEVPRLDSMKPLEKHYSVVLPTVSHSGFLYKTASAGKLLQDRRAREEFSRRWCVL GDGVLSYFENERAVTPNGEIRASEIVCLAVPPPDTHGFEHTFEVYTEGERLYLFGLESAEQAHEWVKCIAKAFVPPLAEDLLARDFERLG RLPYKAGLSLQRAQEGWFSLSGSELRAVFPEGPCEEPLQLRKLQELSIQGDSENQVLVLVERRRTLYIQGERRLDFMGWLGAIQKAAASM GDTLSEQQLGDSDIPVIVYRCVDYITQCGLTSEGIYRKCGQTSKTQRLLESLRQDARSVHLKEGEQHVDDVSSALKRFLRDLPDGLFTRA QRLTWLEASEIEDEEEKVSRYRELLVRLPPVNRATVKALISHLYCVQCFSDTNQMNVHNLAIVFGPTLFQTDGQDYKAGRVVEDLINHYV VVFSVDEEELRKQREEITAIVKMRVAGTASGTQHAGDFICTVYLEEKKAETEQHIKVPASMTAEELTLEILDRRNVGIREKDYWTCFEVN EREEAERPLHFAEKVLPILHGLGTDSHLVVKKHQAMEAMLLYLASRVGDTKHGMMKFREDRSLLGLGLPSGGFHDRYFILNSSCLRLYKE VRNLSVSEARGKILHYQVTLQELTGGKAMTQNITGHTSWTTVIPRTGNWAVAVSAANSKGSSLPTRINIMNLCEAGLLAPRQVSANSEGM DNILVTWQPPRKDPSAVQEYVVEWRELHPGGDTQVPLNWLRSRPYNVSALISEIPYRVSQNSHPINSLQPRVTYVLWMTALTAAGESSHG NEREFCLQGKANWMAFVAPSICIAIIMVGIFSTHYFQQKVFVLLAALRPQWCSREIPDPANSTCAKKYPIAEEKTQLPLDRLLIDWPTPE DPEPLVISEVLHQVTPVFRHPPCSNWPQREKGIQGHQASEKDMMHSASSPPPPRALQAESRQLVDLYKVLESRGSDPKPENPACPWTVLP -------------------------------------------------------------- >5760_5760_37_ARAP1-IL12RB2_ARAP1_chr11_72404370_ENST00000426523_IL12RB2_chr1_67816553_ENST00000262345_length(amino acids)=1664AA_BP=1148 MPTKEEESLLPSLSSPPQPQSEEPLSTLPQGPPQPPSPPPCPPEIPPKPVRLFPEFDDSDYDEVPEEGPGAPARVMTKKEEPPPSRVPRA VRVASLLSEGEELSGDDQGDEEEDDHAYEGVPNGGWHTSSLSLSLPSTIAAPHPMDGPPGGSTPVTPVIKAGWLDKNPPQGSYIYQKRWV RLDTDHLRYFDSNKDAYSKRFISVACISHVAAIGDQKFEVITNNRTFAFRAESDVERKEWMQALQQAMAEQRARARLSSAYLLGVPGSEQ PDRAGSLELRGFKNKLYVAVVGDKVQLYKNLEEYHLGIGITFIDMSVGNVKEVDRRSFDLTTPYRIFSFSADSELEKEQWLEAMQGAIAE ALSTSEVAERIWAAAPNRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTETLIELFLQLGNGAGNRFWAAN VPPSEALQPSSSPSTRRCHLEAKYREGKYRRYHPLFGNQEELDKALCAAVTTTDLAETQALLGCGAGINCFSGDPEAPTPLALAEQAGQT LQMEFLRNNRTTEVPRLDSMKPLEKHYSVVLPTVSHSGFLYKTASAGKLLQDRRAREEFSRRWCVLGDGVLSYFENERAVTPNGEIRASE IVCLAVPPPDTHGFEHTFEVYTEGERLYLFGLESAEQAHEWVKCIAKAFVPPLAEDLLARDFERLGRLPYKAGLSLQRAQEGWFSLSGSE LRAVFPEGPCEEPLQLRKLQELSIQGDSENQVLVLVERRRTLYIQGERRLDFMGWLGAIQKAAASMGDTLSEQQLGDSDIPVIVYRCVDY ITQCGLTSEGIYRKCGQTSKTQRLLESLRQDARSVHLKEGEQHVDDVSSALKRFLRDLPDGLFTRAQRLTWLEASEIEDEEEKVSRYREL LVRLPPVNRATVKALISHLYCVQCFSDTNQMNVHNLAIVFGPTLFQTDGQDYKAGRVVEDLINHYVVVFSVDEEELRKQREEITAIVKMR VAGTASGTQHAGDFICTVYLEEKKAETEQHIKVPASMTAEELTLEILDRRNVGIREKDYWTCFEVNEREEAERPLHFAEKVLPILHGLGT DSHLVVKKHQAMEAMLLYLASRVGDTKHGMMKFREDRSLLGLGLPSGGFHDRYFILNSSCLRLYKEVRNLSVSEARGKILHYQVTLQELT GGKAMTQNITGHTSWTTVIPRTGNWAVAVSAANSKGSSLPTRINIMNLCEAGLLAPRQVSANSEGMDNILVTWQPPRKDPSAVQEYVVEW RELHPGGDTQVPLNWLRSRPYNVSALISENIKSYICYEIRVYALSGDQGGCSSILGNSKHKAPLSGPHINAITEEKGSILISWNSIPVQE QMGCLLHYRIYWKERDSNSQPQLCEIPYRVSQNSHPINSLQPRVTYVLWMTALTAAGESSHGNEREFCLQGKANWMAFVAPSICIAIIMV GIFSTHYFQQKVFVLLAALRPQWCSREIPDPANSTCAKKYPIAEEKTQLPLDRLLIDWPTPEDPEPLVISEVLHQVTPVFRHPPCSNWPQ REKGIQGHQASEKDMMHSASSPPPPRALQAESRQLVDLYKVLESRGSDPKPENPACPWTVLPAGDLPTHDGYLPSNIDDLPSHEAPLADS -------------------------------------------------------------- >5760_5760_38_ARAP1-IL12RB2_ARAP1_chr11_72404370_ENST00000426523_IL12RB2_chr1_67816553_ENST00000371000_length(amino acids)=1461AA_BP=1148 MPTKEEESLLPSLSSPPQPQSEEPLSTLPQGPPQPPSPPPCPPEIPPKPVRLFPEFDDSDYDEVPEEGPGAPARVMTKKEEPPPSRVPRA VRVASLLSEGEELSGDDQGDEEEDDHAYEGVPNGGWHTSSLSLSLPSTIAAPHPMDGPPGGSTPVTPVIKAGWLDKNPPQGSYIYQKRWV RLDTDHLRYFDSNKDAYSKRFISVACISHVAAIGDQKFEVITNNRTFAFRAESDVERKEWMQALQQAMAEQRARARLSSAYLLGVPGSEQ PDRAGSLELRGFKNKLYVAVVGDKVQLYKNLEEYHLGIGITFIDMSVGNVKEVDRRSFDLTTPYRIFSFSADSELEKEQWLEAMQGAIAE ALSTSEVAERIWAAAPNRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTETLIELFLQLGNGAGNRFWAAN VPPSEALQPSSSPSTRRCHLEAKYREGKYRRYHPLFGNQEELDKALCAAVTTTDLAETQALLGCGAGINCFSGDPEAPTPLALAEQAGQT LQMEFLRNNRTTEVPRLDSMKPLEKHYSVVLPTVSHSGFLYKTASAGKLLQDRRAREEFSRRWCVLGDGVLSYFENERAVTPNGEIRASE IVCLAVPPPDTHGFEHTFEVYTEGERLYLFGLESAEQAHEWVKCIAKAFVPPLAEDLLARDFERLGRLPYKAGLSLQRAQEGWFSLSGSE LRAVFPEGPCEEPLQLRKLQELSIQGDSENQVLVLVERRRTLYIQGERRLDFMGWLGAIQKAAASMGDTLSEQQLGDSDIPVIVYRCVDY ITQCGLTSEGIYRKCGQTSKTQRLLESLRQDARSVHLKEGEQHVDDVSSALKRFLRDLPDGLFTRAQRLTWLEASEIEDEEEKVSRYREL LVRLPPVNRATVKALISHLYCVQCFSDTNQMNVHNLAIVFGPTLFQTDGQDYKAGRVVEDLINHYVVVFSVDEEELRKQREEITAIVKMR VAGTASGTQHAGDFICTVYLEEKKAETEQHIKVPASMTAEELTLEILDRRNVGIREKDYWTCFEVNEREEAERPLHFAEKVLPILHGLGT DSHLVVKKHQAMEAMLLYLASRVGDTKHGMMKFREDRSLLGLGLPSGGFHDRYFILNSSCLRLYKEVRNLSVSEARGKILHYQVTLQELT GGKAMTQNITGHTSWTTVIPRTGNWAVAVSAANSKGSSLPTRINIMNLCEAGLLAPRQVSANSEGMDNILVTWQPPRKDPSAVQEYVVEW RELHPGGDTQVPLNWLRSRPYNVSALISENIKSYICYEIRVYALSGDQGGCSSILGNSKHKAPLSGPHINAITEEKGSILISWNSIPVQE QMGCLLHYRIYWKERDSNSQPQLCEIPYRVSQNSHPINSLQPRVTYVLWMTALTAAGESSHGNEREFCLQGKANWMAFVAPSICIAIIMV -------------------------------------------------------------- >5760_5760_39_ARAP1-IL12RB2_ARAP1_chr11_72404370_ENST00000426523_IL12RB2_chr1_67816553_ENST00000541374_length(amino acids)=1461AA_BP=1148 MPTKEEESLLPSLSSPPQPQSEEPLSTLPQGPPQPPSPPPCPPEIPPKPVRLFPEFDDSDYDEVPEEGPGAPARVMTKKEEPPPSRVPRA VRVASLLSEGEELSGDDQGDEEEDDHAYEGVPNGGWHTSSLSLSLPSTIAAPHPMDGPPGGSTPVTPVIKAGWLDKNPPQGSYIYQKRWV RLDTDHLRYFDSNKDAYSKRFISVACISHVAAIGDQKFEVITNNRTFAFRAESDVERKEWMQALQQAMAEQRARARLSSAYLLGVPGSEQ PDRAGSLELRGFKNKLYVAVVGDKVQLYKNLEEYHLGIGITFIDMSVGNVKEVDRRSFDLTTPYRIFSFSADSELEKEQWLEAMQGAIAE ALSTSEVAERIWAAAPNRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTETLIELFLQLGNGAGNRFWAAN VPPSEALQPSSSPSTRRCHLEAKYREGKYRRYHPLFGNQEELDKALCAAVTTTDLAETQALLGCGAGINCFSGDPEAPTPLALAEQAGQT LQMEFLRNNRTTEVPRLDSMKPLEKHYSVVLPTVSHSGFLYKTASAGKLLQDRRAREEFSRRWCVLGDGVLSYFENERAVTPNGEIRASE IVCLAVPPPDTHGFEHTFEVYTEGERLYLFGLESAEQAHEWVKCIAKAFVPPLAEDLLARDFERLGRLPYKAGLSLQRAQEGWFSLSGSE LRAVFPEGPCEEPLQLRKLQELSIQGDSENQVLVLVERRRTLYIQGERRLDFMGWLGAIQKAAASMGDTLSEQQLGDSDIPVIVYRCVDY ITQCGLTSEGIYRKCGQTSKTQRLLESLRQDARSVHLKEGEQHVDDVSSALKRFLRDLPDGLFTRAQRLTWLEASEIEDEEEKVSRYREL LVRLPPVNRATVKALISHLYCVQCFSDTNQMNVHNLAIVFGPTLFQTDGQDYKAGRVVEDLINHYVVVFSVDEEELRKQREEITAIVKMR VAGTASGTQHAGDFICTVYLEEKKAETEQHIKVPASMTAEELTLEILDRRNVGIREKDYWTCFEVNEREEAERPLHFAEKVLPILHGLGT DSHLVVKKHQAMEAMLLYLASRVGDTKHGMMKFREDRSLLGLGLPSGGFHDRYFILNSSCLRLYKEVRNLSVSEARGKILHYQVTLQELT GGKAMTQNITGHTSWTTVIPRTGNWAVAVSAANSKGSSLPTRINIMNLCEAGLLAPRQVSANSEGMDNILVTWQPPRKDPSAVQEYVVEW RELHPGGDTQVPLNWLRSRPYNVSALISENIKSYICYEIRVYALSGDQGGCSSILGNSKHKAPLSGPHINAITEEKGSILISWNSIPVQE QMGCLLHYRIYWKERDSNSQPQLCEIPYRVSQNSHPINSLQPRVTYVLWMTALTAAGESSHGNEREFCLQGKANWMAFVAPSICIAIIMV -------------------------------------------------------------- >5760_5760_40_ARAP1-IL12RB2_ARAP1_chr11_72404370_ENST00000426523_IL12RB2_chr1_67816553_ENST00000544434_length(amino acids)=1578AA_BP=1148 MPTKEEESLLPSLSSPPQPQSEEPLSTLPQGPPQPPSPPPCPPEIPPKPVRLFPEFDDSDYDEVPEEGPGAPARVMTKKEEPPPSRVPRA VRVASLLSEGEELSGDDQGDEEEDDHAYEGVPNGGWHTSSLSLSLPSTIAAPHPMDGPPGGSTPVTPVIKAGWLDKNPPQGSYIYQKRWV RLDTDHLRYFDSNKDAYSKRFISVACISHVAAIGDQKFEVITNNRTFAFRAESDVERKEWMQALQQAMAEQRARARLSSAYLLGVPGSEQ PDRAGSLELRGFKNKLYVAVVGDKVQLYKNLEEYHLGIGITFIDMSVGNVKEVDRRSFDLTTPYRIFSFSADSELEKEQWLEAMQGAIAE ALSTSEVAERIWAAAPNRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTETLIELFLQLGNGAGNRFWAAN VPPSEALQPSSSPSTRRCHLEAKYREGKYRRYHPLFGNQEELDKALCAAVTTTDLAETQALLGCGAGINCFSGDPEAPTPLALAEQAGQT LQMEFLRNNRTTEVPRLDSMKPLEKHYSVVLPTVSHSGFLYKTASAGKLLQDRRAREEFSRRWCVLGDGVLSYFENERAVTPNGEIRASE IVCLAVPPPDTHGFEHTFEVYTEGERLYLFGLESAEQAHEWVKCIAKAFVPPLAEDLLARDFERLGRLPYKAGLSLQRAQEGWFSLSGSE LRAVFPEGPCEEPLQLRKLQELSIQGDSENQVLVLVERRRTLYIQGERRLDFMGWLGAIQKAAASMGDTLSEQQLGDSDIPVIVYRCVDY ITQCGLTSEGIYRKCGQTSKTQRLLESLRQDARSVHLKEGEQHVDDVSSALKRFLRDLPDGLFTRAQRLTWLEASEIEDEEEKVSRYREL LVRLPPVNRATVKALISHLYCVQCFSDTNQMNVHNLAIVFGPTLFQTDGQDYKAGRVVEDLINHYVVVFSVDEEELRKQREEITAIVKMR VAGTASGTQHAGDFICTVYLEEKKAETEQHIKVPASMTAEELTLEILDRRNVGIREKDYWTCFEVNEREEAERPLHFAEKVLPILHGLGT DSHLVVKKHQAMEAMLLYLASRVGDTKHGMMKFREDRSLLGLGLPSGGFHDRYFILNSSCLRLYKEVRNLSVSEARGKILHYQVTLQELT GGKAMTQNITGHTSWTTVIPRTGNWAVAVSAANSKGSSLPTRINIMNLCEAGLLAPRQVSANSEGMDNILVTWQPPRKDPSAVQEYVVEW RELHPGGDTQVPLNWLRSRPYNVSALISEIPYRVSQNSHPINSLQPRVTYVLWMTALTAAGESSHGNEREFCLQGKANWMAFVAPSICIA IIMVGIFSTHYFQQKVFVLLAALRPQWCSREIPDPANSTCAKKYPIAEEKTQLPLDRLLIDWPTPEDPEPLVISEVLHQVTPVFRHPPCS NWPQREKGIQGHQASEKDMMHSASSPPPPRALQAESRQLVDLYKVLESRGSDPKPENPACPWTVLPAGDLPTHDGYLPSNIDDLPSHEAP -------------------------------------------------------------- >5760_5760_41_ARAP1-IL12RB2_ARAP1_chr11_72404370_ENST00000429686_IL12RB2_chr1_67816553_ENST00000262345_length(amino acids)=1603AA_BP=1087 MPTKEEESLLPSLSSPPQPQSEEPLSTLPQGPPQPPSPPPCPPEIPPKPVRLFPEFDDSDYDEVPEEGPGAPARVMTKKEEPPPSRVPRA VRVASLLSEGEELSGDDQGDEEEDDHAYEGVPNGGWHTSSLSLSLPSTIAAPHPMDGPPGGSTPVTPVIKAGWLDKNPPQGSYIYQKRWV RLDTDHLRYFDSNKDAYSKRFISVACISHVAAIGDQKFEVITNNRTFAFRAESDVERKEWMQALQQAMAEQRARARLSSAYLLGVPGSEQ PDRAGSLELRGFKNKLYVAVVGDKVQLYKNLEEYHLGIGITFIDMSVGNVKEVDRRSFDLTTPYRIFSFSADSELEKEQWLEAMQGAIAE ALSTSEVAERIWAAAPNRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTETLIEALCAAVTTTDLAETQAL LGCGAGINCFSGDPEAPTPLALAEQAGQTLQMEFLRNNRTTEVPRLDSMKPLEKHYSVVLPTVSHSGFLYKTASAGKLLQDRRAREEFSR RWCVLGDGVLSYFENERAVTPNGEIRASEIVCLAVPPPDTHGFEHTFEVYTEGERLYLFGLESAEQAHEWVKCIAKAFVPPLAEDLLARD FERLGRLPYKAGLSLQRAQEGWFSLSGSELRAVFPEGPCEEPLQLRKLQELSIQGDSENQVLVLVERRRTLYIQGERRLDFMGWLGAIQK AAASMGDTLSEQQLGDSDIPVIVYRCVDYITQCGLTSEGIYRKCGQTSKTQRLLESLRQDARSVHLKEGEQHVDDVSSALKRFLRDLPDG LFTRAQRLTWLEASEIEDEEEKVSRYRELLVRLPPVNRATVKALISHLYCVQCFSDTNQMNVHNLAIVFGPTLFQTDGQDYKAGRVVEDL INHYVVVFSVDEEELRKQREEITAIVKMRVAGTASGTQHAGDFICTVYLEEKKAETEQHIKVPASMTAEELTLEILDRRNVGIREKDYWT CFEVNEREEAERPLHFAEKVLPILHGLGTDSHLVVKKHQAMEAMLLYLASRVGDTKHGMMKFREDRSLLGLGLPSGGFHDRYFILNSSCL RLYKEVRNLSVSEARGKILHYQVTLQELTGGKAMTQNITGHTSWTTVIPRTGNWAVAVSAANSKGSSLPTRINIMNLCEAGLLAPRQVSA NSEGMDNILVTWQPPRKDPSAVQEYVVEWRELHPGGDTQVPLNWLRSRPYNVSALISENIKSYICYEIRVYALSGDQGGCSSILGNSKHK APLSGPHINAITEEKGSILISWNSIPVQEQMGCLLHYRIYWKERDSNSQPQLCEIPYRVSQNSHPINSLQPRVTYVLWMTALTAAGESSH GNEREFCLQGKANWMAFVAPSICIAIIMVGIFSTHYFQQKVFVLLAALRPQWCSREIPDPANSTCAKKYPIAEEKTQLPLDRLLIDWPTP EDPEPLVISEVLHQVTPVFRHPPCSNWPQREKGIQGHQASEKDMMHSASSPPPPRALQAESRQLVDLYKVLESRGSDPKPENPACPWTVL -------------------------------------------------------------- >5760_5760_42_ARAP1-IL12RB2_ARAP1_chr11_72404370_ENST00000429686_IL12RB2_chr1_67816553_ENST00000371000_length(amino acids)=1400AA_BP=1087 MPTKEEESLLPSLSSPPQPQSEEPLSTLPQGPPQPPSPPPCPPEIPPKPVRLFPEFDDSDYDEVPEEGPGAPARVMTKKEEPPPSRVPRA VRVASLLSEGEELSGDDQGDEEEDDHAYEGVPNGGWHTSSLSLSLPSTIAAPHPMDGPPGGSTPVTPVIKAGWLDKNPPQGSYIYQKRWV RLDTDHLRYFDSNKDAYSKRFISVACISHVAAIGDQKFEVITNNRTFAFRAESDVERKEWMQALQQAMAEQRARARLSSAYLLGVPGSEQ PDRAGSLELRGFKNKLYVAVVGDKVQLYKNLEEYHLGIGITFIDMSVGNVKEVDRRSFDLTTPYRIFSFSADSELEKEQWLEAMQGAIAE ALSTSEVAERIWAAAPNRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTETLIEALCAAVTTTDLAETQAL LGCGAGINCFSGDPEAPTPLALAEQAGQTLQMEFLRNNRTTEVPRLDSMKPLEKHYSVVLPTVSHSGFLYKTASAGKLLQDRRAREEFSR RWCVLGDGVLSYFENERAVTPNGEIRASEIVCLAVPPPDTHGFEHTFEVYTEGERLYLFGLESAEQAHEWVKCIAKAFVPPLAEDLLARD FERLGRLPYKAGLSLQRAQEGWFSLSGSELRAVFPEGPCEEPLQLRKLQELSIQGDSENQVLVLVERRRTLYIQGERRLDFMGWLGAIQK AAASMGDTLSEQQLGDSDIPVIVYRCVDYITQCGLTSEGIYRKCGQTSKTQRLLESLRQDARSVHLKEGEQHVDDVSSALKRFLRDLPDG LFTRAQRLTWLEASEIEDEEEKVSRYRELLVRLPPVNRATVKALISHLYCVQCFSDTNQMNVHNLAIVFGPTLFQTDGQDYKAGRVVEDL INHYVVVFSVDEEELRKQREEITAIVKMRVAGTASGTQHAGDFICTVYLEEKKAETEQHIKVPASMTAEELTLEILDRRNVGIREKDYWT CFEVNEREEAERPLHFAEKVLPILHGLGTDSHLVVKKHQAMEAMLLYLASRVGDTKHGMMKFREDRSLLGLGLPSGGFHDRYFILNSSCL RLYKEVRNLSVSEARGKILHYQVTLQELTGGKAMTQNITGHTSWTTVIPRTGNWAVAVSAANSKGSSLPTRINIMNLCEAGLLAPRQVSA NSEGMDNILVTWQPPRKDPSAVQEYVVEWRELHPGGDTQVPLNWLRSRPYNVSALISENIKSYICYEIRVYALSGDQGGCSSILGNSKHK APLSGPHINAITEEKGSILISWNSIPVQEQMGCLLHYRIYWKERDSNSQPQLCEIPYRVSQNSHPINSLQPRVTYVLWMTALTAAGESSH -------------------------------------------------------------- >5760_5760_43_ARAP1-IL12RB2_ARAP1_chr11_72404370_ENST00000429686_IL12RB2_chr1_67816553_ENST00000541374_length(amino acids)=1400AA_BP=1087 MPTKEEESLLPSLSSPPQPQSEEPLSTLPQGPPQPPSPPPCPPEIPPKPVRLFPEFDDSDYDEVPEEGPGAPARVMTKKEEPPPSRVPRA VRVASLLSEGEELSGDDQGDEEEDDHAYEGVPNGGWHTSSLSLSLPSTIAAPHPMDGPPGGSTPVTPVIKAGWLDKNPPQGSYIYQKRWV RLDTDHLRYFDSNKDAYSKRFISVACISHVAAIGDQKFEVITNNRTFAFRAESDVERKEWMQALQQAMAEQRARARLSSAYLLGVPGSEQ PDRAGSLELRGFKNKLYVAVVGDKVQLYKNLEEYHLGIGITFIDMSVGNVKEVDRRSFDLTTPYRIFSFSADSELEKEQWLEAMQGAIAE ALSTSEVAERIWAAAPNRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTETLIEALCAAVTTTDLAETQAL LGCGAGINCFSGDPEAPTPLALAEQAGQTLQMEFLRNNRTTEVPRLDSMKPLEKHYSVVLPTVSHSGFLYKTASAGKLLQDRRAREEFSR RWCVLGDGVLSYFENERAVTPNGEIRASEIVCLAVPPPDTHGFEHTFEVYTEGERLYLFGLESAEQAHEWVKCIAKAFVPPLAEDLLARD FERLGRLPYKAGLSLQRAQEGWFSLSGSELRAVFPEGPCEEPLQLRKLQELSIQGDSENQVLVLVERRRTLYIQGERRLDFMGWLGAIQK AAASMGDTLSEQQLGDSDIPVIVYRCVDYITQCGLTSEGIYRKCGQTSKTQRLLESLRQDARSVHLKEGEQHVDDVSSALKRFLRDLPDG LFTRAQRLTWLEASEIEDEEEKVSRYRELLVRLPPVNRATVKALISHLYCVQCFSDTNQMNVHNLAIVFGPTLFQTDGQDYKAGRVVEDL INHYVVVFSVDEEELRKQREEITAIVKMRVAGTASGTQHAGDFICTVYLEEKKAETEQHIKVPASMTAEELTLEILDRRNVGIREKDYWT CFEVNEREEAERPLHFAEKVLPILHGLGTDSHLVVKKHQAMEAMLLYLASRVGDTKHGMMKFREDRSLLGLGLPSGGFHDRYFILNSSCL RLYKEVRNLSVSEARGKILHYQVTLQELTGGKAMTQNITGHTSWTTVIPRTGNWAVAVSAANSKGSSLPTRINIMNLCEAGLLAPRQVSA NSEGMDNILVTWQPPRKDPSAVQEYVVEWRELHPGGDTQVPLNWLRSRPYNVSALISENIKSYICYEIRVYALSGDQGGCSSILGNSKHK APLSGPHINAITEEKGSILISWNSIPVQEQMGCLLHYRIYWKERDSNSQPQLCEIPYRVSQNSHPINSLQPRVTYVLWMTALTAAGESSH -------------------------------------------------------------- >5760_5760_44_ARAP1-IL12RB2_ARAP1_chr11_72404370_ENST00000429686_IL12RB2_chr1_67816553_ENST00000544434_length(amino acids)=1517AA_BP=1087 MPTKEEESLLPSLSSPPQPQSEEPLSTLPQGPPQPPSPPPCPPEIPPKPVRLFPEFDDSDYDEVPEEGPGAPARVMTKKEEPPPSRVPRA VRVASLLSEGEELSGDDQGDEEEDDHAYEGVPNGGWHTSSLSLSLPSTIAAPHPMDGPPGGSTPVTPVIKAGWLDKNPPQGSYIYQKRWV RLDTDHLRYFDSNKDAYSKRFISVACISHVAAIGDQKFEVITNNRTFAFRAESDVERKEWMQALQQAMAEQRARARLSSAYLLGVPGSEQ PDRAGSLELRGFKNKLYVAVVGDKVQLYKNLEEYHLGIGITFIDMSVGNVKEVDRRSFDLTTPYRIFSFSADSELEKEQWLEAMQGAIAE ALSTSEVAERIWAAAPNRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTETLIEALCAAVTTTDLAETQAL LGCGAGINCFSGDPEAPTPLALAEQAGQTLQMEFLRNNRTTEVPRLDSMKPLEKHYSVVLPTVSHSGFLYKTASAGKLLQDRRAREEFSR RWCVLGDGVLSYFENERAVTPNGEIRASEIVCLAVPPPDTHGFEHTFEVYTEGERLYLFGLESAEQAHEWVKCIAKAFVPPLAEDLLARD FERLGRLPYKAGLSLQRAQEGWFSLSGSELRAVFPEGPCEEPLQLRKLQELSIQGDSENQVLVLVERRRTLYIQGERRLDFMGWLGAIQK AAASMGDTLSEQQLGDSDIPVIVYRCVDYITQCGLTSEGIYRKCGQTSKTQRLLESLRQDARSVHLKEGEQHVDDVSSALKRFLRDLPDG LFTRAQRLTWLEASEIEDEEEKVSRYRELLVRLPPVNRATVKALISHLYCVQCFSDTNQMNVHNLAIVFGPTLFQTDGQDYKAGRVVEDL INHYVVVFSVDEEELRKQREEITAIVKMRVAGTASGTQHAGDFICTVYLEEKKAETEQHIKVPASMTAEELTLEILDRRNVGIREKDYWT CFEVNEREEAERPLHFAEKVLPILHGLGTDSHLVVKKHQAMEAMLLYLASRVGDTKHGMMKFREDRSLLGLGLPSGGFHDRYFILNSSCL RLYKEVRNLSVSEARGKILHYQVTLQELTGGKAMTQNITGHTSWTTVIPRTGNWAVAVSAANSKGSSLPTRINIMNLCEAGLLAPRQVSA NSEGMDNILVTWQPPRKDPSAVQEYVVEWRELHPGGDTQVPLNWLRSRPYNVSALISEIPYRVSQNSHPINSLQPRVTYVLWMTALTAAG ESSHGNEREFCLQGKANWMAFVAPSICIAIIMVGIFSTHYFQQKVFVLLAALRPQWCSREIPDPANSTCAKKYPIAEEKTQLPLDRLLID WPTPEDPEPLVISEVLHQVTPVFRHPPCSNWPQREKGIQGHQASEKDMMHSASSPPPPRALQAESRQLVDLYKVLESRGSDPKPENPACP -------------------------------------------------------------- >5760_5760_45_ARAP1-IL12RB2_ARAP1_chr11_72404370_ENST00000455638_IL12RB2_chr1_67816553_ENST00000262345_length(amino acids)=1834AA_BP=1318 MAEAGDAALSVAEWLRALHLEQYTGLFEQHGLVWATECQGLSDTRLMDMGMLLPGHRRRILAGLLRAHTSPAPAPRPTPRPVPMKRHIFR SPPVPATPPEPLPTTTEDEGLPAAPPIPPRRSCLPPTCFTTPSTAAPDPVLPPLPAKRHLAELSVPPVPPRTGPPRLLVSLPTKEEESLL PSLSSPPQPQSEEPLSTLPQGPPQPPSPPPCPPEIPPKPVRLFPEFDDSDYDEVPEEGPGAPARVMTKKEEPPPSRVPRAVRVASLLSEG EELSGDDQGDEEEDDHAYEGVPNGGWHTSSLSLSLPSTIAAPHPMDGPPGGSTPVTPVIKAGWLDKNPPQGSYIYQKRWVRLDTDHLRYF DSNKDAYSKRFISVACISHVAAIGDQKFEVITNNRTFAFRAESDVERKEWMQALQQAMAEQRARARLSSAYLLGVPGSEQPDRAGSLELR GFKNKLYVAVVGDKVQLYKNLEEYHLGIGITFIDMSVGNVKEVDRRSFDLTTPYRIFSFSADSELEKEQWLEAMQGAIAEALSTSEVAER IWAAAPNRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTETLIELFLQLGNGAGNRFWAANVPPSEALQPS SSPSTRRCHLEAKYREGKYRRYHPLFGNQEELDKALCAAVTTTDLAETQALLGCGAGINCFSGDPEAPTPLALAEQAGQTLQMEFLRNNR TTEVPRLDSMKPLEKHYSVVLPTVSHSGFLYKTASAGKLLQDRRAREEFSRRWCVLGDGVLSYFENERAVTPNGEIRASEIVCLAVPPPD THGFEHTFEVYTEGERLYLFGLESAEQAHEWVKCIAKAFVPPLAEDLLARDFERLGRLPYKAGLSLQRAQEGWFSLSGSELRAVFPEGPC EEPLQLRKLQELSIQGDSENQVLVLVERRRTLYIQGERRLDFMGWLGAIQKAAASMGDTLSEQQLGDSDIPVIVYRCVDYITQCGLTSEG IYRKCGQTSKTQRLLESLRQDARSVHLKEGEQHVDDVSSALKRFLRDLPDGLFTRAQRLTWLEASEIEDEEEKVSRYRELLVRLPPVNRA TVKALISHLYCVQCFSDTNQMNVHNLAIVFGPTLFQTDGQDYKAGRVVEDLINHYVVVFSVDEEELRKQREEITAIVKMRVAGTASGTQH AGDFICTVYLEEKKAETEQHIKVPASMTAEELTLEILDRRNVGIREKDYWTCFEVNEREEAERPLHFAEKVLPILHGLGTDSHLVVKKHQ AMEAMLLYLASRVGDTKHGMMKFREDRSLLGLGLPSGGFHDRYFILNSSCLRLYKEVRNLSVSEARGKILHYQVTLQELTGGKAMTQNIT GHTSWTTVIPRTGNWAVAVSAANSKGSSLPTRINIMNLCEAGLLAPRQVSANSEGMDNILVTWQPPRKDPSAVQEYVVEWRELHPGGDTQ VPLNWLRSRPYNVSALISENIKSYICYEIRVYALSGDQGGCSSILGNSKHKAPLSGPHINAITEEKGSILISWNSIPVQEQMGCLLHYRI YWKERDSNSQPQLCEIPYRVSQNSHPINSLQPRVTYVLWMTALTAAGESSHGNEREFCLQGKANWMAFVAPSICIAIIMVGIFSTHYFQQ KVFVLLAALRPQWCSREIPDPANSTCAKKYPIAEEKTQLPLDRLLIDWPTPEDPEPLVISEVLHQVTPVFRHPPCSNWPQREKGIQGHQA SEKDMMHSASSPPPPRALQAESRQLVDLYKVLESRGSDPKPENPACPWTVLPAGDLPTHDGYLPSNIDDLPSHEAPLADSLEELEPQHIS -------------------------------------------------------------- >5760_5760_46_ARAP1-IL12RB2_ARAP1_chr11_72404370_ENST00000455638_IL12RB2_chr1_67816553_ENST00000371000_length(amino acids)=1631AA_BP=1318 MAEAGDAALSVAEWLRALHLEQYTGLFEQHGLVWATECQGLSDTRLMDMGMLLPGHRRRILAGLLRAHTSPAPAPRPTPRPVPMKRHIFR SPPVPATPPEPLPTTTEDEGLPAAPPIPPRRSCLPPTCFTTPSTAAPDPVLPPLPAKRHLAELSVPPVPPRTGPPRLLVSLPTKEEESLL PSLSSPPQPQSEEPLSTLPQGPPQPPSPPPCPPEIPPKPVRLFPEFDDSDYDEVPEEGPGAPARVMTKKEEPPPSRVPRAVRVASLLSEG EELSGDDQGDEEEDDHAYEGVPNGGWHTSSLSLSLPSTIAAPHPMDGPPGGSTPVTPVIKAGWLDKNPPQGSYIYQKRWVRLDTDHLRYF DSNKDAYSKRFISVACISHVAAIGDQKFEVITNNRTFAFRAESDVERKEWMQALQQAMAEQRARARLSSAYLLGVPGSEQPDRAGSLELR GFKNKLYVAVVGDKVQLYKNLEEYHLGIGITFIDMSVGNVKEVDRRSFDLTTPYRIFSFSADSELEKEQWLEAMQGAIAEALSTSEVAER IWAAAPNRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTETLIELFLQLGNGAGNRFWAANVPPSEALQPS SSPSTRRCHLEAKYREGKYRRYHPLFGNQEELDKALCAAVTTTDLAETQALLGCGAGINCFSGDPEAPTPLALAEQAGQTLQMEFLRNNR TTEVPRLDSMKPLEKHYSVVLPTVSHSGFLYKTASAGKLLQDRRAREEFSRRWCVLGDGVLSYFENERAVTPNGEIRASEIVCLAVPPPD THGFEHTFEVYTEGERLYLFGLESAEQAHEWVKCIAKAFVPPLAEDLLARDFERLGRLPYKAGLSLQRAQEGWFSLSGSELRAVFPEGPC EEPLQLRKLQELSIQGDSENQVLVLVERRRTLYIQGERRLDFMGWLGAIQKAAASMGDTLSEQQLGDSDIPVIVYRCVDYITQCGLTSEG IYRKCGQTSKTQRLLESLRQDARSVHLKEGEQHVDDVSSALKRFLRDLPDGLFTRAQRLTWLEASEIEDEEEKVSRYRELLVRLPPVNRA TVKALISHLYCVQCFSDTNQMNVHNLAIVFGPTLFQTDGQDYKAGRVVEDLINHYVVVFSVDEEELRKQREEITAIVKMRVAGTASGTQH AGDFICTVYLEEKKAETEQHIKVPASMTAEELTLEILDRRNVGIREKDYWTCFEVNEREEAERPLHFAEKVLPILHGLGTDSHLVVKKHQ AMEAMLLYLASRVGDTKHGMMKFREDRSLLGLGLPSGGFHDRYFILNSSCLRLYKEVRNLSVSEARGKILHYQVTLQELTGGKAMTQNIT GHTSWTTVIPRTGNWAVAVSAANSKGSSLPTRINIMNLCEAGLLAPRQVSANSEGMDNILVTWQPPRKDPSAVQEYVVEWRELHPGGDTQ VPLNWLRSRPYNVSALISENIKSYICYEIRVYALSGDQGGCSSILGNSKHKAPLSGPHINAITEEKGSILISWNSIPVQEQMGCLLHYRI YWKERDSNSQPQLCEIPYRVSQNSHPINSLQPRVTYVLWMTALTAAGESSHGNEREFCLQGKANWMAFVAPSICIAIIMVGIFSTHYFQQ -------------------------------------------------------------- >5760_5760_47_ARAP1-IL12RB2_ARAP1_chr11_72404370_ENST00000455638_IL12RB2_chr1_67816553_ENST00000541374_length(amino acids)=1631AA_BP=1318 MAEAGDAALSVAEWLRALHLEQYTGLFEQHGLVWATECQGLSDTRLMDMGMLLPGHRRRILAGLLRAHTSPAPAPRPTPRPVPMKRHIFR SPPVPATPPEPLPTTTEDEGLPAAPPIPPRRSCLPPTCFTTPSTAAPDPVLPPLPAKRHLAELSVPPVPPRTGPPRLLVSLPTKEEESLL PSLSSPPQPQSEEPLSTLPQGPPQPPSPPPCPPEIPPKPVRLFPEFDDSDYDEVPEEGPGAPARVMTKKEEPPPSRVPRAVRVASLLSEG EELSGDDQGDEEEDDHAYEGVPNGGWHTSSLSLSLPSTIAAPHPMDGPPGGSTPVTPVIKAGWLDKNPPQGSYIYQKRWVRLDTDHLRYF DSNKDAYSKRFISVACISHVAAIGDQKFEVITNNRTFAFRAESDVERKEWMQALQQAMAEQRARARLSSAYLLGVPGSEQPDRAGSLELR GFKNKLYVAVVGDKVQLYKNLEEYHLGIGITFIDMSVGNVKEVDRRSFDLTTPYRIFSFSADSELEKEQWLEAMQGAIAEALSTSEVAER IWAAAPNRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTETLIELFLQLGNGAGNRFWAANVPPSEALQPS SSPSTRRCHLEAKYREGKYRRYHPLFGNQEELDKALCAAVTTTDLAETQALLGCGAGINCFSGDPEAPTPLALAEQAGQTLQMEFLRNNR TTEVPRLDSMKPLEKHYSVVLPTVSHSGFLYKTASAGKLLQDRRAREEFSRRWCVLGDGVLSYFENERAVTPNGEIRASEIVCLAVPPPD THGFEHTFEVYTEGERLYLFGLESAEQAHEWVKCIAKAFVPPLAEDLLARDFERLGRLPYKAGLSLQRAQEGWFSLSGSELRAVFPEGPC EEPLQLRKLQELSIQGDSENQVLVLVERRRTLYIQGERRLDFMGWLGAIQKAAASMGDTLSEQQLGDSDIPVIVYRCVDYITQCGLTSEG IYRKCGQTSKTQRLLESLRQDARSVHLKEGEQHVDDVSSALKRFLRDLPDGLFTRAQRLTWLEASEIEDEEEKVSRYRELLVRLPPVNRA TVKALISHLYCVQCFSDTNQMNVHNLAIVFGPTLFQTDGQDYKAGRVVEDLINHYVVVFSVDEEELRKQREEITAIVKMRVAGTASGTQH AGDFICTVYLEEKKAETEQHIKVPASMTAEELTLEILDRRNVGIREKDYWTCFEVNEREEAERPLHFAEKVLPILHGLGTDSHLVVKKHQ AMEAMLLYLASRVGDTKHGMMKFREDRSLLGLGLPSGGFHDRYFILNSSCLRLYKEVRNLSVSEARGKILHYQVTLQELTGGKAMTQNIT GHTSWTTVIPRTGNWAVAVSAANSKGSSLPTRINIMNLCEAGLLAPRQVSANSEGMDNILVTWQPPRKDPSAVQEYVVEWRELHPGGDTQ VPLNWLRSRPYNVSALISENIKSYICYEIRVYALSGDQGGCSSILGNSKHKAPLSGPHINAITEEKGSILISWNSIPVQEQMGCLLHYRI YWKERDSNSQPQLCEIPYRVSQNSHPINSLQPRVTYVLWMTALTAAGESSHGNEREFCLQGKANWMAFVAPSICIAIIMVGIFSTHYFQQ -------------------------------------------------------------- >5760_5760_48_ARAP1-IL12RB2_ARAP1_chr11_72404370_ENST00000455638_IL12RB2_chr1_67816553_ENST00000544434_length(amino acids)=1748AA_BP=1318 MAEAGDAALSVAEWLRALHLEQYTGLFEQHGLVWATECQGLSDTRLMDMGMLLPGHRRRILAGLLRAHTSPAPAPRPTPRPVPMKRHIFR SPPVPATPPEPLPTTTEDEGLPAAPPIPPRRSCLPPTCFTTPSTAAPDPVLPPLPAKRHLAELSVPPVPPRTGPPRLLVSLPTKEEESLL PSLSSPPQPQSEEPLSTLPQGPPQPPSPPPCPPEIPPKPVRLFPEFDDSDYDEVPEEGPGAPARVMTKKEEPPPSRVPRAVRVASLLSEG EELSGDDQGDEEEDDHAYEGVPNGGWHTSSLSLSLPSTIAAPHPMDGPPGGSTPVTPVIKAGWLDKNPPQGSYIYQKRWVRLDTDHLRYF DSNKDAYSKRFISVACISHVAAIGDQKFEVITNNRTFAFRAESDVERKEWMQALQQAMAEQRARARLSSAYLLGVPGSEQPDRAGSLELR GFKNKLYVAVVGDKVQLYKNLEEYHLGIGITFIDMSVGNVKEVDRRSFDLTTPYRIFSFSADSELEKEQWLEAMQGAIAEALSTSEVAER IWAAAPNRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTETLIELFLQLGNGAGNRFWAANVPPSEALQPS SSPSTRRCHLEAKYREGKYRRYHPLFGNQEELDKALCAAVTTTDLAETQALLGCGAGINCFSGDPEAPTPLALAEQAGQTLQMEFLRNNR TTEVPRLDSMKPLEKHYSVVLPTVSHSGFLYKTASAGKLLQDRRAREEFSRRWCVLGDGVLSYFENERAVTPNGEIRASEIVCLAVPPPD THGFEHTFEVYTEGERLYLFGLESAEQAHEWVKCIAKAFVPPLAEDLLARDFERLGRLPYKAGLSLQRAQEGWFSLSGSELRAVFPEGPC EEPLQLRKLQELSIQGDSENQVLVLVERRRTLYIQGERRLDFMGWLGAIQKAAASMGDTLSEQQLGDSDIPVIVYRCVDYITQCGLTSEG IYRKCGQTSKTQRLLESLRQDARSVHLKEGEQHVDDVSSALKRFLRDLPDGLFTRAQRLTWLEASEIEDEEEKVSRYRELLVRLPPVNRA TVKALISHLYCVQCFSDTNQMNVHNLAIVFGPTLFQTDGQDYKAGRVVEDLINHYVVVFSVDEEELRKQREEITAIVKMRVAGTASGTQH AGDFICTVYLEEKKAETEQHIKVPASMTAEELTLEILDRRNVGIREKDYWTCFEVNEREEAERPLHFAEKVLPILHGLGTDSHLVVKKHQ AMEAMLLYLASRVGDTKHGMMKFREDRSLLGLGLPSGGFHDRYFILNSSCLRLYKEVRNLSVSEARGKILHYQVTLQELTGGKAMTQNIT GHTSWTTVIPRTGNWAVAVSAANSKGSSLPTRINIMNLCEAGLLAPRQVSANSEGMDNILVTWQPPRKDPSAVQEYVVEWRELHPGGDTQ VPLNWLRSRPYNVSALISEIPYRVSQNSHPINSLQPRVTYVLWMTALTAAGESSHGNEREFCLQGKANWMAFVAPSICIAIIMVGIFSTH YFQQKVFVLLAALRPQWCSREIPDPANSTCAKKYPIAEEKTQLPLDRLLIDWPTPEDPEPLVISEVLHQVTPVFRHPPCSNWPQREKGIQ GHQASEKDMMHSASSPPPPRALQAESRQLVDLYKVLESRGSDPKPENPACPWTVLPAGDLPTHDGYLPSNIDDLPSHEAPLADSLEELEP -------------------------------------------------------------- |
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Fusion Protein Functional Features |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr11:72404370/chr1:67816553) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| ARAP1 | IL12RB2 |
| FUNCTION: Phosphatidylinositol 3,4,5-trisphosphate-dependent GTPase-activating protein that modulates actin cytoskeleton remodeling by regulating ARF and RHO family members. Is activated by phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3) binding. Can be activated by phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4,5)P2) binding, albeit with lower efficiency. Has a preference for ARF1 and ARF5 (By similarity). {ECO:0000250, ECO:0000269|PubMed:11804590}. | FUNCTION: Receptor for interleukin-12. This subunit is the signaling component coupling to the JAK2/STAT4 pathway. Promotes the proliferation of T-cells as well as NK cells. Induces the promotion of T-cells towards the Th1 phenotype by strongly enhancing IFN-gamma production. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - Retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | ARAP1 | chr11:72404369 | chr1:67816552 | ENST00000334211 | - | 27 | 33 | 327_419 | 1073.0 | 1206.0 | Domain | PH 1 |
| Hgene | ARAP1 | chr11:72404369 | chr1:67816552 | ENST00000334211 | - | 27 | 33 | 440_529 | 1073.0 | 1206.0 | Domain | PH 2 |
| Hgene | ARAP1 | chr11:72404369 | chr1:67816552 | ENST00000334211 | - | 27 | 33 | 535_660 | 1073.0 | 1206.0 | Domain | Arf-GAP |
| Hgene | ARAP1 | chr11:72404369 | chr1:67816552 | ENST00000334211 | - | 27 | 33 | 6_70 | 1073.0 | 1206.0 | Domain | SAM |
| Hgene | ARAP1 | chr11:72404369 | chr1:67816552 | ENST00000334211 | - | 27 | 33 | 743_850 | 1073.0 | 1206.0 | Domain | PH 3 |
| Hgene | ARAP1 | chr11:72404369 | chr1:67816552 | ENST00000359373 | - | 29 | 34 | 1172_1261 | 1318.0 | 1440.0 | Domain | Ras-associating |
| Hgene | ARAP1 | chr11:72404369 | chr1:67816552 | ENST00000359373 | - | 29 | 34 | 327_419 | 1318.0 | 1440.0 | Domain | PH 1 |
| Hgene | ARAP1 | chr11:72404369 | chr1:67816552 | ENST00000359373 | - | 29 | 34 | 440_529 | 1318.0 | 1440.0 | Domain | PH 2 |
| Hgene | ARAP1 | chr11:72404369 | chr1:67816552 | ENST00000359373 | - | 29 | 34 | 535_660 | 1318.0 | 1440.0 | Domain | Arf-GAP |
| Hgene | ARAP1 | chr11:72404369 | chr1:67816552 | ENST00000359373 | - | 29 | 34 | 6_70 | 1318.0 | 1440.0 | Domain | SAM |
| Hgene | ARAP1 | chr11:72404369 | chr1:67816552 | ENST00000359373 | - | 29 | 34 | 743_850 | 1318.0 | 1440.0 | Domain | PH 3 |
| Hgene | ARAP1 | chr11:72404369 | chr1:67816552 | ENST00000359373 | - | 29 | 34 | 954_1139 | 1318.0 | 1440.0 | Domain | Rho-GAP |
| Hgene | ARAP1 | chr11:72404369 | chr1:67816552 | ENST00000393605 | - | 24 | 30 | 327_419 | 1078.0 | 1211.0 | Domain | PH 1 |
| Hgene | ARAP1 | chr11:72404369 | chr1:67816552 | ENST00000393605 | - | 24 | 30 | 440_529 | 1078.0 | 1211.0 | Domain | PH 2 |
| Hgene | ARAP1 | chr11:72404369 | chr1:67816552 | ENST00000393605 | - | 24 | 30 | 535_660 | 1078.0 | 1211.0 | Domain | Arf-GAP |
| Hgene | ARAP1 | chr11:72404369 | chr1:67816552 | ENST00000393605 | - | 24 | 30 | 6_70 | 1078.0 | 1211.0 | Domain | SAM |
| Hgene | ARAP1 | chr11:72404369 | chr1:67816552 | ENST00000393605 | - | 24 | 30 | 743_850 | 1078.0 | 1211.0 | Domain | PH 3 |
| Hgene | ARAP1 | chr11:72404369 | chr1:67816552 | ENST00000393609 | - | 29 | 35 | 1172_1261 | 1318.0 | 1451.0 | Domain | Ras-associating |
| Hgene | ARAP1 | chr11:72404369 | chr1:67816552 | ENST00000393609 | - | 29 | 35 | 327_419 | 1318.0 | 1451.0 | Domain | PH 1 |
| Hgene | ARAP1 | chr11:72404369 | chr1:67816552 | ENST00000393609 | - | 29 | 35 | 440_529 | 1318.0 | 1451.0 | Domain | PH 2 |
| Hgene | ARAP1 | chr11:72404369 | chr1:67816552 | ENST00000393609 | - | 29 | 35 | 535_660 | 1318.0 | 1451.0 | Domain | Arf-GAP |
| Hgene | ARAP1 | chr11:72404369 | chr1:67816552 | ENST00000393609 | - | 29 | 35 | 6_70 | 1318.0 | 1451.0 | Domain | SAM |
| Hgene | ARAP1 | chr11:72404369 | chr1:67816552 | ENST00000393609 | - | 29 | 35 | 743_850 | 1318.0 | 1451.0 | Domain | PH 3 |
| Hgene | ARAP1 | chr11:72404369 | chr1:67816552 | ENST00000393609 | - | 29 | 35 | 954_1139 | 1318.0 | 1451.0 | Domain | Rho-GAP |
| Hgene | ARAP1 | chr11:72404369 | chr1:67816552 | ENST00000429686 | - | 26 | 31 | 327_419 | 1012.0 | 1134.0 | Domain | PH 1 |
| Hgene | ARAP1 | chr11:72404369 | chr1:67816552 | ENST00000429686 | - | 26 | 31 | 440_529 | 1012.0 | 1134.0 | Domain | PH 2 |
| Hgene | ARAP1 | chr11:72404369 | chr1:67816552 | ENST00000429686 | - | 26 | 31 | 535_660 | 1012.0 | 1134.0 | Domain | Arf-GAP |
| Hgene | ARAP1 | chr11:72404369 | chr1:67816552 | ENST00000429686 | - | 26 | 31 | 6_70 | 1012.0 | 1134.0 | Domain | SAM |
| Hgene | ARAP1 | chr11:72404369 | chr1:67816552 | ENST00000429686 | - | 26 | 31 | 743_850 | 1012.0 | 1134.0 | Domain | PH 3 |
| Hgene | ARAP1 | chr11:72404369 | chr1:67816552 | ENST00000455638 | - | 27 | 32 | 1172_1261 | 1318.0 | 1440.0 | Domain | Ras-associating |
| Hgene | ARAP1 | chr11:72404369 | chr1:67816552 | ENST00000455638 | - | 27 | 32 | 327_419 | 1318.0 | 1440.0 | Domain | PH 1 |
| Hgene | ARAP1 | chr11:72404369 | chr1:67816552 | ENST00000455638 | - | 27 | 32 | 440_529 | 1318.0 | 1440.0 | Domain | PH 2 |
| Hgene | ARAP1 | chr11:72404369 | chr1:67816552 | ENST00000455638 | - | 27 | 32 | 535_660 | 1318.0 | 1440.0 | Domain | Arf-GAP |
| Hgene | ARAP1 | chr11:72404369 | chr1:67816552 | ENST00000455638 | - | 27 | 32 | 6_70 | 1318.0 | 1440.0 | Domain | SAM |
| Hgene | ARAP1 | chr11:72404369 | chr1:67816552 | ENST00000455638 | - | 27 | 32 | 743_850 | 1318.0 | 1440.0 | Domain | PH 3 |
| Hgene | ARAP1 | chr11:72404369 | chr1:67816552 | ENST00000455638 | - | 27 | 32 | 954_1139 | 1318.0 | 1440.0 | Domain | Rho-GAP |
| Hgene | ARAP1 | chr11:72404370 | chr1:67816553 | ENST00000334211 | - | 27 | 33 | 327_419 | 1073.0 | 1206.0 | Domain | PH 1 |
| Hgene | ARAP1 | chr11:72404370 | chr1:67816553 | ENST00000334211 | - | 27 | 33 | 440_529 | 1073.0 | 1206.0 | Domain | PH 2 |
| Hgene | ARAP1 | chr11:72404370 | chr1:67816553 | ENST00000334211 | - | 27 | 33 | 535_660 | 1073.0 | 1206.0 | Domain | Arf-GAP |
| Hgene | ARAP1 | chr11:72404370 | chr1:67816553 | ENST00000334211 | - | 27 | 33 | 6_70 | 1073.0 | 1206.0 | Domain | SAM |
| Hgene | ARAP1 | chr11:72404370 | chr1:67816553 | ENST00000334211 | - | 27 | 33 | 743_850 | 1073.0 | 1206.0 | Domain | PH 3 |
| Hgene | ARAP1 | chr11:72404370 | chr1:67816553 | ENST00000359373 | - | 29 | 34 | 1172_1261 | 1318.0 | 1440.0 | Domain | Ras-associating |
| Hgene | ARAP1 | chr11:72404370 | chr1:67816553 | ENST00000359373 | - | 29 | 34 | 327_419 | 1318.0 | 1440.0 | Domain | PH 1 |
| Hgene | ARAP1 | chr11:72404370 | chr1:67816553 | ENST00000359373 | - | 29 | 34 | 440_529 | 1318.0 | 1440.0 | Domain | PH 2 |
| Hgene | ARAP1 | chr11:72404370 | chr1:67816553 | ENST00000359373 | - | 29 | 34 | 535_660 | 1318.0 | 1440.0 | Domain | Arf-GAP |
| Hgene | ARAP1 | chr11:72404370 | chr1:67816553 | ENST00000359373 | - | 29 | 34 | 6_70 | 1318.0 | 1440.0 | Domain | SAM |
| Hgene | ARAP1 | chr11:72404370 | chr1:67816553 | ENST00000359373 | - | 29 | 34 | 743_850 | 1318.0 | 1440.0 | Domain | PH 3 |
| Hgene | ARAP1 | chr11:72404370 | chr1:67816553 | ENST00000359373 | - | 29 | 34 | 954_1139 | 1318.0 | 1440.0 | Domain | Rho-GAP |
| Hgene | ARAP1 | chr11:72404370 | chr1:67816553 | ENST00000393605 | - | 24 | 30 | 327_419 | 1078.0 | 1211.0 | Domain | PH 1 |
| Hgene | ARAP1 | chr11:72404370 | chr1:67816553 | ENST00000393605 | - | 24 | 30 | 440_529 | 1078.0 | 1211.0 | Domain | PH 2 |
| Hgene | ARAP1 | chr11:72404370 | chr1:67816553 | ENST00000393605 | - | 24 | 30 | 535_660 | 1078.0 | 1211.0 | Domain | Arf-GAP |
| Hgene | ARAP1 | chr11:72404370 | chr1:67816553 | ENST00000393605 | - | 24 | 30 | 6_70 | 1078.0 | 1211.0 | Domain | SAM |
| Hgene | ARAP1 | chr11:72404370 | chr1:67816553 | ENST00000393605 | - | 24 | 30 | 743_850 | 1078.0 | 1211.0 | Domain | PH 3 |
| Hgene | ARAP1 | chr11:72404370 | chr1:67816553 | ENST00000393609 | - | 29 | 35 | 1172_1261 | 1318.0 | 1451.0 | Domain | Ras-associating |
| Hgene | ARAP1 | chr11:72404370 | chr1:67816553 | ENST00000393609 | - | 29 | 35 | 327_419 | 1318.0 | 1451.0 | Domain | PH 1 |
| Hgene | ARAP1 | chr11:72404370 | chr1:67816553 | ENST00000393609 | - | 29 | 35 | 440_529 | 1318.0 | 1451.0 | Domain | PH 2 |
| Hgene | ARAP1 | chr11:72404370 | chr1:67816553 | ENST00000393609 | - | 29 | 35 | 535_660 | 1318.0 | 1451.0 | Domain | Arf-GAP |
| Hgene | ARAP1 | chr11:72404370 | chr1:67816553 | ENST00000393609 | - | 29 | 35 | 6_70 | 1318.0 | 1451.0 | Domain | SAM |
| Hgene | ARAP1 | chr11:72404370 | chr1:67816553 | ENST00000393609 | - | 29 | 35 | 743_850 | 1318.0 | 1451.0 | Domain | PH 3 |
| Hgene | ARAP1 | chr11:72404370 | chr1:67816553 | ENST00000393609 | - | 29 | 35 | 954_1139 | 1318.0 | 1451.0 | Domain | Rho-GAP |
| Hgene | ARAP1 | chr11:72404370 | chr1:67816553 | ENST00000429686 | - | 26 | 31 | 327_419 | 1012.0 | 1134.0 | Domain | PH 1 |
| Hgene | ARAP1 | chr11:72404370 | chr1:67816553 | ENST00000429686 | - | 26 | 31 | 440_529 | 1012.0 | 1134.0 | Domain | PH 2 |
| Hgene | ARAP1 | chr11:72404370 | chr1:67816553 | ENST00000429686 | - | 26 | 31 | 535_660 | 1012.0 | 1134.0 | Domain | Arf-GAP |
| Hgene | ARAP1 | chr11:72404370 | chr1:67816553 | ENST00000429686 | - | 26 | 31 | 6_70 | 1012.0 | 1134.0 | Domain | SAM |
| Hgene | ARAP1 | chr11:72404370 | chr1:67816553 | ENST00000429686 | - | 26 | 31 | 743_850 | 1012.0 | 1134.0 | Domain | PH 3 |
| Hgene | ARAP1 | chr11:72404370 | chr1:67816553 | ENST00000455638 | - | 27 | 32 | 1172_1261 | 1318.0 | 1440.0 | Domain | Ras-associating |
| Hgene | ARAP1 | chr11:72404370 | chr1:67816553 | ENST00000455638 | - | 27 | 32 | 327_419 | 1318.0 | 1440.0 | Domain | PH 1 |
| Hgene | ARAP1 | chr11:72404370 | chr1:67816553 | ENST00000455638 | - | 27 | 32 | 440_529 | 1318.0 | 1440.0 | Domain | PH 2 |
| Hgene | ARAP1 | chr11:72404370 | chr1:67816553 | ENST00000455638 | - | 27 | 32 | 535_660 | 1318.0 | 1440.0 | Domain | Arf-GAP |
| Hgene | ARAP1 | chr11:72404370 | chr1:67816553 | ENST00000455638 | - | 27 | 32 | 6_70 | 1318.0 | 1440.0 | Domain | SAM |
| Hgene | ARAP1 | chr11:72404370 | chr1:67816553 | ENST00000455638 | - | 27 | 32 | 743_850 | 1318.0 | 1440.0 | Domain | PH 3 |
| Hgene | ARAP1 | chr11:72404370 | chr1:67816553 | ENST00000455638 | - | 27 | 32 | 954_1139 | 1318.0 | 1440.0 | Domain | Rho-GAP |
| Hgene | ARAP1 | chr11:72404369 | chr1:67816552 | ENST00000334211 | - | 27 | 33 | 550_576 | 1073.0 | 1206.0 | Zinc finger | C4-type |
| Hgene | ARAP1 | chr11:72404369 | chr1:67816552 | ENST00000359373 | - | 29 | 34 | 550_576 | 1318.0 | 1440.0 | Zinc finger | C4-type |
| Hgene | ARAP1 | chr11:72404369 | chr1:67816552 | ENST00000393605 | - | 24 | 30 | 550_576 | 1078.0 | 1211.0 | Zinc finger | C4-type |
| Hgene | ARAP1 | chr11:72404369 | chr1:67816552 | ENST00000393609 | - | 29 | 35 | 550_576 | 1318.0 | 1451.0 | Zinc finger | C4-type |
| Hgene | ARAP1 | chr11:72404369 | chr1:67816552 | ENST00000429686 | - | 26 | 31 | 550_576 | 1012.0 | 1134.0 | Zinc finger | C4-type |
| Hgene | ARAP1 | chr11:72404369 | chr1:67816552 | ENST00000455638 | - | 27 | 32 | 550_576 | 1318.0 | 1440.0 | Zinc finger | C4-type |
| Hgene | ARAP1 | chr11:72404370 | chr1:67816553 | ENST00000334211 | - | 27 | 33 | 550_576 | 1073.0 | 1206.0 | Zinc finger | C4-type |
| Hgene | ARAP1 | chr11:72404370 | chr1:67816553 | ENST00000359373 | - | 29 | 34 | 550_576 | 1318.0 | 1440.0 | Zinc finger | C4-type |
| Hgene | ARAP1 | chr11:72404370 | chr1:67816553 | ENST00000393605 | - | 24 | 30 | 550_576 | 1078.0 | 1211.0 | Zinc finger | C4-type |
| Hgene | ARAP1 | chr11:72404370 | chr1:67816553 | ENST00000393609 | - | 29 | 35 | 550_576 | 1318.0 | 1451.0 | Zinc finger | C4-type |
| Hgene | ARAP1 | chr11:72404370 | chr1:67816553 | ENST00000429686 | - | 26 | 31 | 550_576 | 1012.0 | 1134.0 | Zinc finger | C4-type |
| Hgene | ARAP1 | chr11:72404370 | chr1:67816553 | ENST00000455638 | - | 27 | 32 | 550_576 | 1318.0 | 1440.0 | Zinc finger | C4-type |
| Tgene | IL12RB2 | chr11:72404369 | chr1:67816552 | ENST00000262345 | 7 | 16 | 750_753 | 346.0 | 863.0 | Compositional bias | Note=Poly-Pro | |
| Tgene | IL12RB2 | chr11:72404369 | chr1:67816552 | ENST00000371000 | 7 | 15 | 750_753 | 346.0 | 660.0 | Compositional bias | Note=Poly-Pro | |
| Tgene | IL12RB2 | chr11:72404369 | chr1:67816552 | ENST00000541374 | 8 | 16 | 750_753 | 346.0 | 660.0 | Compositional bias | Note=Poly-Pro | |
| Tgene | IL12RB2 | chr11:72404369 | chr1:67816552 | ENST00000544434 | 7 | 14 | 750_753 | 346.0 | 777.0 | Compositional bias | Note=Poly-Pro | |
| Tgene | IL12RB2 | chr11:72404370 | chr1:67816553 | ENST00000262345 | 7 | 16 | 750_753 | 346.0 | 863.0 | Compositional bias | Note=Poly-Pro | |
| Tgene | IL12RB2 | chr11:72404370 | chr1:67816553 | ENST00000371000 | 7 | 15 | 750_753 | 346.0 | 660.0 | Compositional bias | Note=Poly-Pro | |
| Tgene | IL12RB2 | chr11:72404370 | chr1:67816553 | ENST00000541374 | 8 | 16 | 750_753 | 346.0 | 660.0 | Compositional bias | Note=Poly-Pro | |
| Tgene | IL12RB2 | chr11:72404370 | chr1:67816553 | ENST00000544434 | 7 | 14 | 750_753 | 346.0 | 777.0 | Compositional bias | Note=Poly-Pro | |
| Tgene | IL12RB2 | chr11:72404369 | chr1:67816552 | ENST00000262345 | 7 | 16 | 423_520 | 346.0 | 863.0 | Domain | Fibronectin type-III 4 | |
| Tgene | IL12RB2 | chr11:72404369 | chr1:67816552 | ENST00000262345 | 7 | 16 | 521_620 | 346.0 | 863.0 | Domain | Fibronectin type-III 5 | |
| Tgene | IL12RB2 | chr11:72404369 | chr1:67816552 | ENST00000371000 | 7 | 15 | 423_520 | 346.0 | 660.0 | Domain | Fibronectin type-III 4 | |
| Tgene | IL12RB2 | chr11:72404369 | chr1:67816552 | ENST00000371000 | 7 | 15 | 521_620 | 346.0 | 660.0 | Domain | Fibronectin type-III 5 | |
| Tgene | IL12RB2 | chr11:72404369 | chr1:67816552 | ENST00000541374 | 8 | 16 | 423_520 | 346.0 | 660.0 | Domain | Fibronectin type-III 4 | |
| Tgene | IL12RB2 | chr11:72404369 | chr1:67816552 | ENST00000541374 | 8 | 16 | 521_620 | 346.0 | 660.0 | Domain | Fibronectin type-III 5 | |
| Tgene | IL12RB2 | chr11:72404369 | chr1:67816552 | ENST00000544434 | 7 | 14 | 423_520 | 346.0 | 777.0 | Domain | Fibronectin type-III 4 | |
| Tgene | IL12RB2 | chr11:72404369 | chr1:67816552 | ENST00000544434 | 7 | 14 | 521_620 | 346.0 | 777.0 | Domain | Fibronectin type-III 5 | |
| Tgene | IL12RB2 | chr11:72404370 | chr1:67816553 | ENST00000262345 | 7 | 16 | 423_520 | 346.0 | 863.0 | Domain | Fibronectin type-III 4 | |
| Tgene | IL12RB2 | chr11:72404370 | chr1:67816553 | ENST00000262345 | 7 | 16 | 521_620 | 346.0 | 863.0 | Domain | Fibronectin type-III 5 | |
| Tgene | IL12RB2 | chr11:72404370 | chr1:67816553 | ENST00000371000 | 7 | 15 | 423_520 | 346.0 | 660.0 | Domain | Fibronectin type-III 4 | |
| Tgene | IL12RB2 | chr11:72404370 | chr1:67816553 | ENST00000371000 | 7 | 15 | 521_620 | 346.0 | 660.0 | Domain | Fibronectin type-III 5 | |
| Tgene | IL12RB2 | chr11:72404370 | chr1:67816553 | ENST00000541374 | 8 | 16 | 423_520 | 346.0 | 660.0 | Domain | Fibronectin type-III 4 | |
| Tgene | IL12RB2 | chr11:72404370 | chr1:67816553 | ENST00000541374 | 8 | 16 | 521_620 | 346.0 | 660.0 | Domain | Fibronectin type-III 5 | |
| Tgene | IL12RB2 | chr11:72404370 | chr1:67816553 | ENST00000544434 | 7 | 14 | 423_520 | 346.0 | 777.0 | Domain | Fibronectin type-III 4 | |
| Tgene | IL12RB2 | chr11:72404370 | chr1:67816553 | ENST00000544434 | 7 | 14 | 521_620 | 346.0 | 777.0 | Domain | Fibronectin type-III 5 | |
| Tgene | IL12RB2 | chr11:72404369 | chr1:67816552 | ENST00000262345 | 7 | 16 | 662_670 | 346.0 | 863.0 | Motif | Note=Box 1 motif | |
| Tgene | IL12RB2 | chr11:72404369 | chr1:67816552 | ENST00000371000 | 7 | 15 | 662_670 | 346.0 | 660.0 | Motif | Note=Box 1 motif | |
| Tgene | IL12RB2 | chr11:72404369 | chr1:67816552 | ENST00000541374 | 8 | 16 | 662_670 | 346.0 | 660.0 | Motif | Note=Box 1 motif | |
| Tgene | IL12RB2 | chr11:72404369 | chr1:67816552 | ENST00000544434 | 7 | 14 | 662_670 | 346.0 | 777.0 | Motif | Note=Box 1 motif | |
| Tgene | IL12RB2 | chr11:72404370 | chr1:67816553 | ENST00000262345 | 7 | 16 | 662_670 | 346.0 | 863.0 | Motif | Note=Box 1 motif | |
| Tgene | IL12RB2 | chr11:72404370 | chr1:67816553 | ENST00000371000 | 7 | 15 | 662_670 | 346.0 | 660.0 | Motif | Note=Box 1 motif | |
| Tgene | IL12RB2 | chr11:72404370 | chr1:67816553 | ENST00000541374 | 8 | 16 | 662_670 | 346.0 | 660.0 | Motif | Note=Box 1 motif | |
| Tgene | IL12RB2 | chr11:72404370 | chr1:67816553 | ENST00000544434 | 7 | 14 | 662_670 | 346.0 | 777.0 | Motif | Note=Box 1 motif | |
| Tgene | IL12RB2 | chr11:72404369 | chr1:67816552 | ENST00000262345 | 7 | 16 | 796_801 | 346.0 | 863.0 | Region | Note=Required for STAT4 binding | |
| Tgene | IL12RB2 | chr11:72404369 | chr1:67816552 | ENST00000371000 | 7 | 15 | 796_801 | 346.0 | 660.0 | Region | Note=Required for STAT4 binding | |
| Tgene | IL12RB2 | chr11:72404369 | chr1:67816552 | ENST00000541374 | 8 | 16 | 796_801 | 346.0 | 660.0 | Region | Note=Required for STAT4 binding | |
| Tgene | IL12RB2 | chr11:72404369 | chr1:67816552 | ENST00000544434 | 7 | 14 | 796_801 | 346.0 | 777.0 | Region | Note=Required for STAT4 binding | |
| Tgene | IL12RB2 | chr11:72404370 | chr1:67816553 | ENST00000262345 | 7 | 16 | 796_801 | 346.0 | 863.0 | Region | Note=Required for STAT4 binding | |
| Tgene | IL12RB2 | chr11:72404370 | chr1:67816553 | ENST00000371000 | 7 | 15 | 796_801 | 346.0 | 660.0 | Region | Note=Required for STAT4 binding | |
| Tgene | IL12RB2 | chr11:72404370 | chr1:67816553 | ENST00000541374 | 8 | 16 | 796_801 | 346.0 | 660.0 | Region | Note=Required for STAT4 binding | |
| Tgene | IL12RB2 | chr11:72404370 | chr1:67816553 | ENST00000544434 | 7 | 14 | 796_801 | 346.0 | 777.0 | Region | Note=Required for STAT4 binding | |
| Tgene | IL12RB2 | chr11:72404369 | chr1:67816552 | ENST00000262345 | 7 | 16 | 644_862 | 346.0 | 863.0 | Topological domain | Cytoplasmic | |
| Tgene | IL12RB2 | chr11:72404369 | chr1:67816552 | ENST00000371000 | 7 | 15 | 644_862 | 346.0 | 660.0 | Topological domain | Cytoplasmic | |
| Tgene | IL12RB2 | chr11:72404369 | chr1:67816552 | ENST00000541374 | 8 | 16 | 644_862 | 346.0 | 660.0 | Topological domain | Cytoplasmic | |
| Tgene | IL12RB2 | chr11:72404369 | chr1:67816552 | ENST00000544434 | 7 | 14 | 644_862 | 346.0 | 777.0 | Topological domain | Cytoplasmic | |
| Tgene | IL12RB2 | chr11:72404370 | chr1:67816553 | ENST00000262345 | 7 | 16 | 644_862 | 346.0 | 863.0 | Topological domain | Cytoplasmic | |
| Tgene | IL12RB2 | chr11:72404370 | chr1:67816553 | ENST00000371000 | 7 | 15 | 644_862 | 346.0 | 660.0 | Topological domain | Cytoplasmic | |
| Tgene | IL12RB2 | chr11:72404370 | chr1:67816553 | ENST00000541374 | 8 | 16 | 644_862 | 346.0 | 660.0 | Topological domain | Cytoplasmic | |
| Tgene | IL12RB2 | chr11:72404370 | chr1:67816553 | ENST00000544434 | 7 | 14 | 644_862 | 346.0 | 777.0 | Topological domain | Cytoplasmic | |
| Tgene | IL12RB2 | chr11:72404369 | chr1:67816552 | ENST00000262345 | 7 | 16 | 623_643 | 346.0 | 863.0 | Transmembrane | Helical | |
| Tgene | IL12RB2 | chr11:72404369 | chr1:67816552 | ENST00000371000 | 7 | 15 | 623_643 | 346.0 | 660.0 | Transmembrane | Helical | |
| Tgene | IL12RB2 | chr11:72404369 | chr1:67816552 | ENST00000541374 | 8 | 16 | 623_643 | 346.0 | 660.0 | Transmembrane | Helical | |
| Tgene | IL12RB2 | chr11:72404369 | chr1:67816552 | ENST00000544434 | 7 | 14 | 623_643 | 346.0 | 777.0 | Transmembrane | Helical | |
| Tgene | IL12RB2 | chr11:72404370 | chr1:67816553 | ENST00000262345 | 7 | 16 | 623_643 | 346.0 | 863.0 | Transmembrane | Helical | |
| Tgene | IL12RB2 | chr11:72404370 | chr1:67816553 | ENST00000371000 | 7 | 15 | 623_643 | 346.0 | 660.0 | Transmembrane | Helical | |
| Tgene | IL12RB2 | chr11:72404370 | chr1:67816553 | ENST00000541374 | 8 | 16 | 623_643 | 346.0 | 660.0 | Transmembrane | Helical | |
| Tgene | IL12RB2 | chr11:72404370 | chr1:67816553 | ENST00000544434 | 7 | 14 | 623_643 | 346.0 | 777.0 | Transmembrane | Helical |
| - Not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | ARAP1 | chr11:72404369 | chr1:67816552 | ENST00000334211 | - | 27 | 33 | 1172_1261 | 1073.0 | 1206.0 | Domain | Ras-associating |
| Hgene | ARAP1 | chr11:72404369 | chr1:67816552 | ENST00000334211 | - | 27 | 33 | 1274_1396 | 1073.0 | 1206.0 | Domain | PH 4 |
| Hgene | ARAP1 | chr11:72404369 | chr1:67816552 | ENST00000334211 | - | 27 | 33 | 954_1139 | 1073.0 | 1206.0 | Domain | Rho-GAP |
| Hgene | ARAP1 | chr11:72404369 | chr1:67816552 | ENST00000359373 | - | 29 | 34 | 1274_1396 | 1318.0 | 1440.0 | Domain | PH 4 |
| Hgene | ARAP1 | chr11:72404369 | chr1:67816552 | ENST00000393605 | - | 24 | 30 | 1172_1261 | 1078.0 | 1211.0 | Domain | Ras-associating |
| Hgene | ARAP1 | chr11:72404369 | chr1:67816552 | ENST00000393605 | - | 24 | 30 | 1274_1396 | 1078.0 | 1211.0 | Domain | PH 4 |
| Hgene | ARAP1 | chr11:72404369 | chr1:67816552 | ENST00000393605 | - | 24 | 30 | 954_1139 | 1078.0 | 1211.0 | Domain | Rho-GAP |
| Hgene | ARAP1 | chr11:72404369 | chr1:67816552 | ENST00000393609 | - | 29 | 35 | 1274_1396 | 1318.0 | 1451.0 | Domain | PH 4 |
| Hgene | ARAP1 | chr11:72404369 | chr1:67816552 | ENST00000429686 | - | 26 | 31 | 1172_1261 | 1012.0 | 1134.0 | Domain | Ras-associating |
| Hgene | ARAP1 | chr11:72404369 | chr1:67816552 | ENST00000429686 | - | 26 | 31 | 1274_1396 | 1012.0 | 1134.0 | Domain | PH 4 |
| Hgene | ARAP1 | chr11:72404369 | chr1:67816552 | ENST00000429686 | - | 26 | 31 | 954_1139 | 1012.0 | 1134.0 | Domain | Rho-GAP |
| Hgene | ARAP1 | chr11:72404369 | chr1:67816552 | ENST00000455638 | - | 27 | 32 | 1274_1396 | 1318.0 | 1440.0 | Domain | PH 4 |
| Hgene | ARAP1 | chr11:72404370 | chr1:67816553 | ENST00000334211 | - | 27 | 33 | 1172_1261 | 1073.0 | 1206.0 | Domain | Ras-associating |
| Hgene | ARAP1 | chr11:72404370 | chr1:67816553 | ENST00000334211 | - | 27 | 33 | 1274_1396 | 1073.0 | 1206.0 | Domain | PH 4 |
| Hgene | ARAP1 | chr11:72404370 | chr1:67816553 | ENST00000334211 | - | 27 | 33 | 954_1139 | 1073.0 | 1206.0 | Domain | Rho-GAP |
| Hgene | ARAP1 | chr11:72404370 | chr1:67816553 | ENST00000359373 | - | 29 | 34 | 1274_1396 | 1318.0 | 1440.0 | Domain | PH 4 |
| Hgene | ARAP1 | chr11:72404370 | chr1:67816553 | ENST00000393605 | - | 24 | 30 | 1172_1261 | 1078.0 | 1211.0 | Domain | Ras-associating |
| Hgene | ARAP1 | chr11:72404370 | chr1:67816553 | ENST00000393605 | - | 24 | 30 | 1274_1396 | 1078.0 | 1211.0 | Domain | PH 4 |
| Hgene | ARAP1 | chr11:72404370 | chr1:67816553 | ENST00000393605 | - | 24 | 30 | 954_1139 | 1078.0 | 1211.0 | Domain | Rho-GAP |
| Hgene | ARAP1 | chr11:72404370 | chr1:67816553 | ENST00000393609 | - | 29 | 35 | 1274_1396 | 1318.0 | 1451.0 | Domain | PH 4 |
| Hgene | ARAP1 | chr11:72404370 | chr1:67816553 | ENST00000429686 | - | 26 | 31 | 1172_1261 | 1012.0 | 1134.0 | Domain | Ras-associating |
| Hgene | ARAP1 | chr11:72404370 | chr1:67816553 | ENST00000429686 | - | 26 | 31 | 1274_1396 | 1012.0 | 1134.0 | Domain | PH 4 |
| Hgene | ARAP1 | chr11:72404370 | chr1:67816553 | ENST00000429686 | - | 26 | 31 | 954_1139 | 1012.0 | 1134.0 | Domain | Rho-GAP |
| Hgene | ARAP1 | chr11:72404370 | chr1:67816553 | ENST00000455638 | - | 27 | 32 | 1274_1396 | 1318.0 | 1440.0 | Domain | PH 4 |
| Tgene | IL12RB2 | chr11:72404369 | chr1:67816552 | ENST00000262345 | 7 | 16 | 208_211 | 346.0 | 863.0 | Compositional bias | Note=Poly-Ser | |
| Tgene | IL12RB2 | chr11:72404369 | chr1:67816552 | ENST00000371000 | 7 | 15 | 208_211 | 346.0 | 660.0 | Compositional bias | Note=Poly-Ser | |
| Tgene | IL12RB2 | chr11:72404369 | chr1:67816552 | ENST00000541374 | 8 | 16 | 208_211 | 346.0 | 660.0 | Compositional bias | Note=Poly-Ser | |
| Tgene | IL12RB2 | chr11:72404369 | chr1:67816552 | ENST00000544434 | 7 | 14 | 208_211 | 346.0 | 777.0 | Compositional bias | Note=Poly-Ser | |
| Tgene | IL12RB2 | chr11:72404370 | chr1:67816553 | ENST00000262345 | 7 | 16 | 208_211 | 346.0 | 863.0 | Compositional bias | Note=Poly-Ser | |
| Tgene | IL12RB2 | chr11:72404370 | chr1:67816553 | ENST00000371000 | 7 | 15 | 208_211 | 346.0 | 660.0 | Compositional bias | Note=Poly-Ser | |
| Tgene | IL12RB2 | chr11:72404370 | chr1:67816553 | ENST00000541374 | 8 | 16 | 208_211 | 346.0 | 660.0 | Compositional bias | Note=Poly-Ser | |
| Tgene | IL12RB2 | chr11:72404370 | chr1:67816553 | ENST00000544434 | 7 | 14 | 208_211 | 346.0 | 777.0 | Compositional bias | Note=Poly-Ser | |
| Tgene | IL12RB2 | chr11:72404369 | chr1:67816552 | ENST00000262345 | 7 | 16 | 126_221 | 346.0 | 863.0 | Domain | Fibronectin type-III 1 | |
| Tgene | IL12RB2 | chr11:72404369 | chr1:67816552 | ENST00000262345 | 7 | 16 | 226_319 | 346.0 | 863.0 | Domain | Fibronectin type-III 2 | |
| Tgene | IL12RB2 | chr11:72404369 | chr1:67816552 | ENST00000262345 | 7 | 16 | 320_419 | 346.0 | 863.0 | Domain | Fibronectin type-III 3 | |
| Tgene | IL12RB2 | chr11:72404369 | chr1:67816552 | ENST00000371000 | 7 | 15 | 126_221 | 346.0 | 660.0 | Domain | Fibronectin type-III 1 | |
| Tgene | IL12RB2 | chr11:72404369 | chr1:67816552 | ENST00000371000 | 7 | 15 | 226_319 | 346.0 | 660.0 | Domain | Fibronectin type-III 2 | |
| Tgene | IL12RB2 | chr11:72404369 | chr1:67816552 | ENST00000371000 | 7 | 15 | 320_419 | 346.0 | 660.0 | Domain | Fibronectin type-III 3 | |
| Tgene | IL12RB2 | chr11:72404369 | chr1:67816552 | ENST00000541374 | 8 | 16 | 126_221 | 346.0 | 660.0 | Domain | Fibronectin type-III 1 | |
| Tgene | IL12RB2 | chr11:72404369 | chr1:67816552 | ENST00000541374 | 8 | 16 | 226_319 | 346.0 | 660.0 | Domain | Fibronectin type-III 2 | |
| Tgene | IL12RB2 | chr11:72404369 | chr1:67816552 | ENST00000541374 | 8 | 16 | 320_419 | 346.0 | 660.0 | Domain | Fibronectin type-III 3 | |
| Tgene | IL12RB2 | chr11:72404369 | chr1:67816552 | ENST00000544434 | 7 | 14 | 126_221 | 346.0 | 777.0 | Domain | Fibronectin type-III 1 | |
| Tgene | IL12RB2 | chr11:72404369 | chr1:67816552 | ENST00000544434 | 7 | 14 | 226_319 | 346.0 | 777.0 | Domain | Fibronectin type-III 2 | |
| Tgene | IL12RB2 | chr11:72404369 | chr1:67816552 | ENST00000544434 | 7 | 14 | 320_419 | 346.0 | 777.0 | Domain | Fibronectin type-III 3 | |
| Tgene | IL12RB2 | chr11:72404370 | chr1:67816553 | ENST00000262345 | 7 | 16 | 126_221 | 346.0 | 863.0 | Domain | Fibronectin type-III 1 | |
| Tgene | IL12RB2 | chr11:72404370 | chr1:67816553 | ENST00000262345 | 7 | 16 | 226_319 | 346.0 | 863.0 | Domain | Fibronectin type-III 2 | |
| Tgene | IL12RB2 | chr11:72404370 | chr1:67816553 | ENST00000262345 | 7 | 16 | 320_419 | 346.0 | 863.0 | Domain | Fibronectin type-III 3 | |
| Tgene | IL12RB2 | chr11:72404370 | chr1:67816553 | ENST00000371000 | 7 | 15 | 126_221 | 346.0 | 660.0 | Domain | Fibronectin type-III 1 | |
| Tgene | IL12RB2 | chr11:72404370 | chr1:67816553 | ENST00000371000 | 7 | 15 | 226_319 | 346.0 | 660.0 | Domain | Fibronectin type-III 2 | |
| Tgene | IL12RB2 | chr11:72404370 | chr1:67816553 | ENST00000371000 | 7 | 15 | 320_419 | 346.0 | 660.0 | Domain | Fibronectin type-III 3 | |
| Tgene | IL12RB2 | chr11:72404370 | chr1:67816553 | ENST00000541374 | 8 | 16 | 126_221 | 346.0 | 660.0 | Domain | Fibronectin type-III 1 | |
| Tgene | IL12RB2 | chr11:72404370 | chr1:67816553 | ENST00000541374 | 8 | 16 | 226_319 | 346.0 | 660.0 | Domain | Fibronectin type-III 2 | |
| Tgene | IL12RB2 | chr11:72404370 | chr1:67816553 | ENST00000541374 | 8 | 16 | 320_419 | 346.0 | 660.0 | Domain | Fibronectin type-III 3 | |
| Tgene | IL12RB2 | chr11:72404370 | chr1:67816553 | ENST00000544434 | 7 | 14 | 126_221 | 346.0 | 777.0 | Domain | Fibronectin type-III 1 | |
| Tgene | IL12RB2 | chr11:72404370 | chr1:67816553 | ENST00000544434 | 7 | 14 | 226_319 | 346.0 | 777.0 | Domain | Fibronectin type-III 2 | |
| Tgene | IL12RB2 | chr11:72404370 | chr1:67816553 | ENST00000544434 | 7 | 14 | 320_419 | 346.0 | 777.0 | Domain | Fibronectin type-III 3 | |
| Tgene | IL12RB2 | chr11:72404369 | chr1:67816552 | ENST00000262345 | 7 | 16 | 305_309 | 346.0 | 863.0 | Motif | Note=WSXWS motif | |
| Tgene | IL12RB2 | chr11:72404369 | chr1:67816552 | ENST00000371000 | 7 | 15 | 305_309 | 346.0 | 660.0 | Motif | Note=WSXWS motif | |
| Tgene | IL12RB2 | chr11:72404369 | chr1:67816552 | ENST00000541374 | 8 | 16 | 305_309 | 346.0 | 660.0 | Motif | Note=WSXWS motif | |
| Tgene | IL12RB2 | chr11:72404369 | chr1:67816552 | ENST00000544434 | 7 | 14 | 305_309 | 346.0 | 777.0 | Motif | Note=WSXWS motif | |
| Tgene | IL12RB2 | chr11:72404370 | chr1:67816553 | ENST00000262345 | 7 | 16 | 305_309 | 346.0 | 863.0 | Motif | Note=WSXWS motif | |
| Tgene | IL12RB2 | chr11:72404370 | chr1:67816553 | ENST00000371000 | 7 | 15 | 305_309 | 346.0 | 660.0 | Motif | Note=WSXWS motif | |
| Tgene | IL12RB2 | chr11:72404370 | chr1:67816553 | ENST00000541374 | 8 | 16 | 305_309 | 346.0 | 660.0 | Motif | Note=WSXWS motif | |
| Tgene | IL12RB2 | chr11:72404370 | chr1:67816553 | ENST00000544434 | 7 | 14 | 305_309 | 346.0 | 777.0 | Motif | Note=WSXWS motif | |
| Tgene | IL12RB2 | chr11:72404369 | chr1:67816552 | ENST00000262345 | 7 | 16 | 24_622 | 346.0 | 863.0 | Topological domain | Extracellular | |
| Tgene | IL12RB2 | chr11:72404369 | chr1:67816552 | ENST00000371000 | 7 | 15 | 24_622 | 346.0 | 660.0 | Topological domain | Extracellular | |
| Tgene | IL12RB2 | chr11:72404369 | chr1:67816552 | ENST00000541374 | 8 | 16 | 24_622 | 346.0 | 660.0 | Topological domain | Extracellular | |
| Tgene | IL12RB2 | chr11:72404369 | chr1:67816552 | ENST00000544434 | 7 | 14 | 24_622 | 346.0 | 777.0 | Topological domain | Extracellular | |
| Tgene | IL12RB2 | chr11:72404370 | chr1:67816553 | ENST00000262345 | 7 | 16 | 24_622 | 346.0 | 863.0 | Topological domain | Extracellular | |
| Tgene | IL12RB2 | chr11:72404370 | chr1:67816553 | ENST00000371000 | 7 | 15 | 24_622 | 346.0 | 660.0 | Topological domain | Extracellular | |
| Tgene | IL12RB2 | chr11:72404370 | chr1:67816553 | ENST00000541374 | 8 | 16 | 24_622 | 346.0 | 660.0 | Topological domain | Extracellular | |
| Tgene | IL12RB2 | chr11:72404370 | chr1:67816553 | ENST00000544434 | 7 | 14 | 24_622 | 346.0 | 777.0 | Topological domain | Extracellular |
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Fusion Protein Structures |
| PDB and CIF files of the predicted fusion proteins * Here we show the 3D structure of the fusion proteins using Mol*. AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Model confidence is shown from the pLDDT values per residue. pLDDT corresponds to the model’s prediction of its score on the local Distance Difference Test. It is a measure of local accuracy (from AlphfaFold website). To color code individual residues, we transformed individual PDB files into CIF format. |
| Fusion protein PDB link (fusion AA seq ID in FusionPDB) | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | AA seq | Len(AA seq) |
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pLDDT score distribution |
| pLDDT score distribution of the predicted wild-type structures of two partner proteins from AlphaFold2 * AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. |
ARAP1_pLDDT.png  |
IL12RB2_pLDDT.png  |
| pLDDT score distribution of the predicted fusion protein structures from AlphaFold2 * AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. |
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Ramachandran Plot of Fusion Protein Structure |
| Ramachandran plot of the torsional angles - phi (φ)and psi (ψ) - of the residues (amino acids) contained in this fusion protein peptide. |
| Fusion AA seq ID in FusionPDB and their Ramachandran plots |
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Fusion Protein-Protein Interaction |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type from validated records (BIOGRID-3.4.160) |
| Gene | PPI interactors |
| Protein-protein interactors based on sequence similarity (STRING) |
| Gene | STRING network |
| ARAP1 | |
| IL12RB2 |
| - Retained interactions in fusion protein (protein functional feature from UniProt). |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost interactions due to fusion (protein functional feature from UniProt). |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs to ARAP1-IL12RB2 |
| Drugs used for this fusion-positive patient. (Manual curation of PubMed, 04-30-2022 + MyCancerGenome) |
| Hgene | Tgene | Drug | Source | PMID |
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Related Diseases to ARAP1-IL12RB2 |
| Diseases that have this fusion gene. (Manual curation of PubMed, 04-30-2022 + MyCancerGenome) |
| Hgene | Tgene | Disease | Source | PMID |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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