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Fusion Protein:PAX5-FOXP1 |
Fusion Protein Summary |
 Fusion gene summary |
| Fusion partner gene information | Fusion gene name: PAX5-FOXP1 | FusionPDB ID: 62950 | FusionGDB2.0 ID: 62950 | Hgene | Tgene | Gene symbol | PAX5 | FOXP1 | Gene ID | 5079 | 27086 |
| Gene name | paired box 5 | forkhead box P1 | |
| Synonyms | ALL3|BSAP | 12CC4|HSPC215|MFH|QRF1|hFKH1B | |
| Cytomap | 9p13.2 | 3p13 | |
| Type of gene | protein-coding | protein-coding | |
| Description | paired box protein Pax-5B-cell lineage specific activatorpaired box homeotic gene 5paired domain gene 5transcription factor PAX 5 | forkhead box protein P1fork head-related protein like Bglutamine-rich factor 1mac-1-regulated forkhead | |
| Modification date | 20200313 | 20200329 | |
| UniProtAcc | Q02548 | Q9H334 | |
| Ensembl transtripts involved in fusion gene | ENST ids | ENST00000358127, ENST00000377847, ENST00000377852, ENST00000377853, ENST00000414447, ENST00000446742, ENST00000520154, ENST00000520281, ENST00000522003, ENST00000523145, ENST00000523241, | ENST00000318779, ENST00000468577, ENST00000472382, ENST00000491238, ENST00000498215, ENST00000318789, ENST00000475937, ENST00000484350, ENST00000493089, |
| Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0) | * DoF score | 15 X 15 X 7=1575 | 47 X 26 X 20=24440 |
| # samples | 10 | 52 | |
| ** MAII score | log2(10/1575*10)=-3.97727992349992 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(52/24440*10)=-5.55458885167764 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context (manual curation of fusion genes in FusionPDB) | PubMed: PAX5 [Title/Abstract] AND FOXP1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0) | PAX5(37034075)-FOXP1(71008061), # samples:1 PAX5(36966545)-FOXP1(71161791), # samples:1 PAX5(37002645)-FOXP1(71064806), # samples:1 | ||
| Anticipated loss of major functional domain due to fusion event. | PAX5-FOXP1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. PAX5-FOXP1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. PAX5-FOXP1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. PAX5-FOXP1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. PAX5-FOXP1 seems lost the major protein functional domain in Hgene partner, which is a CGC due to the frame-shifted ORF. PAX5-FOXP1 seems lost the major protein functional domain in Hgene partner, which is a transcription factor due to the frame-shifted ORF. PAX5-FOXP1 seems lost the major protein functional domain in Hgene partner, which is a tumor suppressor due to the frame-shifted ORF. PAX5-FOXP1 seems lost the major protein functional domain in Tgene partner, which is a CGC due to the frame-shifted ORF. PAX5-FOXP1 seems lost the major protein functional domain in Tgene partner, which is a epigenetic factor due to the frame-shifted ORF. PAX5-FOXP1 seems lost the major protein functional domain in Tgene partner, which is a transcription factor due to the frame-shifted ORF. PAX5-FOXP1 seems lost the major protein functional domain in Tgene partner, which is a tumor suppressor due to the frame-shifted ORF. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | FOXP1 | GO:0002903 | negative regulation of B cell apoptotic process | 25267198 |
| Tgene | FOXP1 | GO:0010629 | negative regulation of gene expression | 30111844 |
| Tgene | FOXP1 | GO:0030316 | osteoclast differentiation | 18799727 |
| Tgene | FOXP1 | GO:0032496 | response to lipopolysaccharide | 18799727 |
| Tgene | FOXP1 | GO:0032680 | regulation of tumor necrosis factor production | 18799727 |
| Tgene | FOXP1 | GO:0035926 | chemokine (C-C motif) ligand 2 secretion | 18799727 |
| Tgene | FOXP1 | GO:0036035 | osteoclast development | 18799727 |
| Tgene | FOXP1 | GO:0042116 | macrophage activation | 18799727 |
| Tgene | FOXP1 | GO:0042117 | monocyte activation | 18799727 |
| Tgene | FOXP1 | GO:0045655 | regulation of monocyte differentiation | 15286807 |
| Tgene | FOXP1 | GO:0045892 | negative regulation of transcription, DNA-templated | 20950788 |
| Tgene | FOXP1 | GO:0050706 | regulation of interleukin-1 beta secretion | 18799727 |
| Tgene | FOXP1 | GO:0050727 | regulation of inflammatory response | 18799727 |
| Tgene | FOXP1 | GO:0060766 | negative regulation of androgen receptor signaling pathway | 18640093 |
| Tgene | FOXP1 | GO:1900424 | regulation of defense response to bacterium | 18799727 |
| Tgene | FOXP1 | GO:1901256 | regulation of macrophage colony-stimulating factor production | 18799727 |
| Tgene | FOXP1 | GO:2001182 | regulation of interleukin-12 secretion | 18799727 |
| Fusion gene breakpoints across PAX5 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across FOXP1 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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Fusion Gene Sample Information |
| Fusion gene information from FusionGDB2.0. |
| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | acute lymphoblastic leukemia;lymphoblastic lymphoma;B cell acute lymphoblastic leukemia | DQ845346 | PAX5 | chr9 | 37034075 | FOXP1 | chr3 | 71008061 | ||
| ChiTaRS5.0 | N/A | DQ845346 | PAX5 | chr9 | 36966545 | - | FOXP1 | chr3 | 71161791 | - |
| ChiTaRS5.0 | N/A | EU784145 | PAX5 | chr9 | 37002645 | - | FOXP1 | chr3 | 71064806 | - |
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Fusion ORF Analysis |
| Fusion information from ORFfinder translation from full-length transcript sequence from FusionPDB. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000358127 | PAX5 | chr9 | 36966545 | - | ENST00000318789 | FOXP1 | chr3 | 71161791 | - | 7263 | 855 | 75 | 2708 | 877 |
| ENST00000358127 | PAX5 | chr9 | 36966545 | - | ENST00000475937 | FOXP1 | chr3 | 71161791 | - | 5211 | 855 | 75 | 2708 | 877 |
| ENST00000358127 | PAX5 | chr9 | 36966545 | - | ENST00000493089 | FOXP1 | chr3 | 71161791 | - | 2749 | 855 | 75 | 2705 | 876 |
| ENST00000358127 | PAX5 | chr9 | 36966545 | - | ENST00000484350 | FOXP1 | chr3 | 71161791 | - | 2517 | 855 | 75 | 2480 | 801 |
| ENST00000523241 | PAX5 | chr9 | 36966545 | - | ENST00000318789 | FOXP1 | chr3 | 71161791 | - | 7198 | 790 | 10 | 2643 | 877 |
| ENST00000523241 | PAX5 | chr9 | 36966545 | - | ENST00000475937 | FOXP1 | chr3 | 71161791 | - | 5146 | 790 | 10 | 2643 | 877 |
| ENST00000523241 | PAX5 | chr9 | 36966545 | - | ENST00000493089 | FOXP1 | chr3 | 71161791 | - | 2684 | 790 | 10 | 2640 | 876 |
| ENST00000523241 | PAX5 | chr9 | 36966545 | - | ENST00000484350 | FOXP1 | chr3 | 71161791 | - | 2452 | 790 | 10 | 2415 | 801 |
| ENST00000520154 | PAX5 | chr9 | 36966545 | - | ENST00000318789 | FOXP1 | chr3 | 71161791 | - | 7198 | 790 | 10 | 2643 | 877 |
| ENST00000520154 | PAX5 | chr9 | 36966545 | - | ENST00000475937 | FOXP1 | chr3 | 71161791 | - | 5146 | 790 | 10 | 2643 | 877 |
| ENST00000520154 | PAX5 | chr9 | 36966545 | - | ENST00000493089 | FOXP1 | chr3 | 71161791 | - | 2684 | 790 | 10 | 2640 | 876 |
| ENST00000520154 | PAX5 | chr9 | 36966545 | - | ENST00000484350 | FOXP1 | chr3 | 71161791 | - | 2452 | 790 | 10 | 2415 | 801 |
| ENST00000377852 | PAX5 | chr9 | 36966545 | - | ENST00000318789 | FOXP1 | chr3 | 71161791 | - | 7198 | 790 | 10 | 2643 | 877 |
| ENST00000377852 | PAX5 | chr9 | 36966545 | - | ENST00000475937 | FOXP1 | chr3 | 71161791 | - | 5146 | 790 | 10 | 2643 | 877 |
| ENST00000377852 | PAX5 | chr9 | 36966545 | - | ENST00000493089 | FOXP1 | chr3 | 71161791 | - | 2684 | 790 | 10 | 2640 | 876 |
| ENST00000377852 | PAX5 | chr9 | 36966545 | - | ENST00000484350 | FOXP1 | chr3 | 71161791 | - | 2452 | 790 | 10 | 2415 | 801 |
| ENST00000377853 | PAX5 | chr9 | 36966545 | - | ENST00000318789 | FOXP1 | chr3 | 71161791 | - | 7198 | 790 | 10 | 2643 | 877 |
| ENST00000377853 | PAX5 | chr9 | 36966545 | - | ENST00000475937 | FOXP1 | chr3 | 71161791 | - | 5146 | 790 | 10 | 2643 | 877 |
| ENST00000377853 | PAX5 | chr9 | 36966545 | - | ENST00000493089 | FOXP1 | chr3 | 71161791 | - | 2684 | 790 | 10 | 2640 | 876 |
| ENST00000377853 | PAX5 | chr9 | 36966545 | - | ENST00000484350 | FOXP1 | chr3 | 71161791 | - | 2452 | 790 | 10 | 2415 | 801 |
| ENST00000520281 | PAX5 | chr9 | 36966545 | - | ENST00000318789 | FOXP1 | chr3 | 71161791 | - | 7059 | 651 | 0 | 2504 | 834 |
| ENST00000520281 | PAX5 | chr9 | 36966545 | - | ENST00000475937 | FOXP1 | chr3 | 71161791 | - | 5007 | 651 | 0 | 2504 | 834 |
| ENST00000520281 | PAX5 | chr9 | 36966545 | - | ENST00000493089 | FOXP1 | chr3 | 71161791 | - | 2545 | 651 | 0 | 2501 | 833 |
| ENST00000520281 | PAX5 | chr9 | 36966545 | - | ENST00000484350 | FOXP1 | chr3 | 71161791 | - | 2313 | 651 | 0 | 2276 | 758 |
| ENST00000414447 | PAX5 | chr9 | 36966545 | - | ENST00000318789 | FOXP1 | chr3 | 71161791 | - | 7059 | 651 | 0 | 2504 | 834 |
| ENST00000414447 | PAX5 | chr9 | 36966545 | - | ENST00000475937 | FOXP1 | chr3 | 71161791 | - | 5007 | 651 | 0 | 2504 | 834 |
| ENST00000414447 | PAX5 | chr9 | 36966545 | - | ENST00000493089 | FOXP1 | chr3 | 71161791 | - | 2545 | 651 | 0 | 2501 | 833 |
| ENST00000414447 | PAX5 | chr9 | 36966545 | - | ENST00000484350 | FOXP1 | chr3 | 71161791 | - | 2313 | 651 | 0 | 2276 | 758 |
| ENST00000446742 | PAX5 | chr9 | 36966545 | - | ENST00000318789 | FOXP1 | chr3 | 71161791 | - | 6990 | 582 | 0 | 2435 | 811 |
| ENST00000446742 | PAX5 | chr9 | 36966545 | - | ENST00000475937 | FOXP1 | chr3 | 71161791 | - | 4938 | 582 | 0 | 2435 | 811 |
| ENST00000446742 | PAX5 | chr9 | 36966545 | - | ENST00000493089 | FOXP1 | chr3 | 71161791 | - | 2476 | 582 | 0 | 2432 | 810 |
| ENST00000446742 | PAX5 | chr9 | 36966545 | - | ENST00000484350 | FOXP1 | chr3 | 71161791 | - | 2244 | 582 | 0 | 2207 | 735 |
| ENST00000377847 | PAX5 | chr9 | 36966545 | - | ENST00000318789 | FOXP1 | chr3 | 71161791 | - | 7188 | 780 | 0 | 2633 | 877 |
| ENST00000377847 | PAX5 | chr9 | 36966545 | - | ENST00000475937 | FOXP1 | chr3 | 71161791 | - | 5136 | 780 | 0 | 2633 | 877 |
| ENST00000377847 | PAX5 | chr9 | 36966545 | - | ENST00000493089 | FOXP1 | chr3 | 71161791 | - | 2674 | 780 | 0 | 2630 | 876 |
| ENST00000377847 | PAX5 | chr9 | 36966545 | - | ENST00000484350 | FOXP1 | chr3 | 71161791 | - | 2442 | 780 | 0 | 2405 | 801 |
| ENST00000522003 | PAX5 | chr9 | 37002645 | - | ENST00000318789 | FOXP1 | chr3 | 71064806 | - | 6157 | 438 | 439 | 1602 | 387 |
| ENST00000522003 | PAX5 | chr9 | 37002645 | - | ENST00000475937 | FOXP1 | chr3 | 71064806 | - | 4105 | 438 | 439 | 1602 | 387 |
| ENST00000522003 | PAX5 | chr9 | 37002645 | - | ENST00000493089 | FOXP1 | chr3 | 71064806 | - | 1643 | 438 | 439 | 1599 | 386 |
| ENST00000522003 | PAX5 | chr9 | 37002645 | - | ENST00000484350 | FOXP1 | chr3 | 71064806 | - | 1639 | 438 | 439 | 1602 | 387 |
| ENST00000523145 | PAX5 | chr9 | 37002645 | - | ENST00000318789 | FOXP1 | chr3 | 71064806 | - | 6157 | 438 | 439 | 1602 | 387 |
| ENST00000523145 | PAX5 | chr9 | 37002645 | - | ENST00000475937 | FOXP1 | chr3 | 71064806 | - | 4105 | 438 | 439 | 1602 | 387 |
| ENST00000523145 | PAX5 | chr9 | 37002645 | - | ENST00000493089 | FOXP1 | chr3 | 71064806 | - | 1643 | 438 | 439 | 1599 | 386 |
| ENST00000523145 | PAX5 | chr9 | 37002645 | - | ENST00000484350 | FOXP1 | chr3 | 71064806 | - | 1639 | 438 | 439 | 1602 | 387 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000358127 | ENST00000318789 | PAX5 | chr9 | 36966545 | - | FOXP1 | chr3 | 71161791 | - | 0.000532785 | 0.9994672 |
| ENST00000358127 | ENST00000475937 | PAX5 | chr9 | 36966545 | - | FOXP1 | chr3 | 71161791 | - | 0.001319939 | 0.99868006 |
| ENST00000358127 | ENST00000493089 | PAX5 | chr9 | 36966545 | - | FOXP1 | chr3 | 71161791 | - | 0.013093269 | 0.98690677 |
| ENST00000358127 | ENST00000484350 | PAX5 | chr9 | 36966545 | - | FOXP1 | chr3 | 71161791 | - | 0.015788043 | 0.984212 |
| ENST00000523241 | ENST00000318789 | PAX5 | chr9 | 36966545 | - | FOXP1 | chr3 | 71161791 | - | 0.000543986 | 0.999456 |
| ENST00000523241 | ENST00000475937 | PAX5 | chr9 | 36966545 | - | FOXP1 | chr3 | 71161791 | - | 0.001432878 | 0.9985671 |
| ENST00000523241 | ENST00000493089 | PAX5 | chr9 | 36966545 | - | FOXP1 | chr3 | 71161791 | - | 0.014002087 | 0.9859979 |
| ENST00000523241 | ENST00000484350 | PAX5 | chr9 | 36966545 | - | FOXP1 | chr3 | 71161791 | - | 0.017108316 | 0.9828917 |
| ENST00000520154 | ENST00000318789 | PAX5 | chr9 | 36966545 | - | FOXP1 | chr3 | 71161791 | - | 0.000543986 | 0.999456 |
| ENST00000520154 | ENST00000475937 | PAX5 | chr9 | 36966545 | - | FOXP1 | chr3 | 71161791 | - | 0.001432878 | 0.9985671 |
| ENST00000520154 | ENST00000493089 | PAX5 | chr9 | 36966545 | - | FOXP1 | chr3 | 71161791 | - | 0.014002087 | 0.9859979 |
| ENST00000520154 | ENST00000484350 | PAX5 | chr9 | 36966545 | - | FOXP1 | chr3 | 71161791 | - | 0.017108316 | 0.9828917 |
| ENST00000377852 | ENST00000318789 | PAX5 | chr9 | 36966545 | - | FOXP1 | chr3 | 71161791 | - | 0.000543986 | 0.999456 |
| ENST00000377852 | ENST00000475937 | PAX5 | chr9 | 36966545 | - | FOXP1 | chr3 | 71161791 | - | 0.001432878 | 0.9985671 |
| ENST00000377852 | ENST00000493089 | PAX5 | chr9 | 36966545 | - | FOXP1 | chr3 | 71161791 | - | 0.014002087 | 0.9859979 |
| ENST00000377852 | ENST00000484350 | PAX5 | chr9 | 36966545 | - | FOXP1 | chr3 | 71161791 | - | 0.017108316 | 0.9828917 |
| ENST00000377853 | ENST00000318789 | PAX5 | chr9 | 36966545 | - | FOXP1 | chr3 | 71161791 | - | 0.000543986 | 0.999456 |
| ENST00000377853 | ENST00000475937 | PAX5 | chr9 | 36966545 | - | FOXP1 | chr3 | 71161791 | - | 0.001432878 | 0.9985671 |
| ENST00000377853 | ENST00000493089 | PAX5 | chr9 | 36966545 | - | FOXP1 | chr3 | 71161791 | - | 0.014002087 | 0.9859979 |
| ENST00000377853 | ENST00000484350 | PAX5 | chr9 | 36966545 | - | FOXP1 | chr3 | 71161791 | - | 0.017108316 | 0.9828917 |
| ENST00000520281 | ENST00000318789 | PAX5 | chr9 | 36966545 | - | FOXP1 | chr3 | 71161791 | - | 0.000579099 | 0.9994209 |
| ENST00000520281 | ENST00000475937 | PAX5 | chr9 | 36966545 | - | FOXP1 | chr3 | 71161791 | - | 0.001709782 | 0.99829024 |
| ENST00000520281 | ENST00000493089 | PAX5 | chr9 | 36966545 | - | FOXP1 | chr3 | 71161791 | - | 0.017946793 | 0.98205316 |
| ENST00000520281 | ENST00000484350 | PAX5 | chr9 | 36966545 | - | FOXP1 | chr3 | 71161791 | - | 0.020157738 | 0.97984225 |
| ENST00000414447 | ENST00000318789 | PAX5 | chr9 | 36966545 | - | FOXP1 | chr3 | 71161791 | - | 0.000579099 | 0.9994209 |
| ENST00000414447 | ENST00000475937 | PAX5 | chr9 | 36966545 | - | FOXP1 | chr3 | 71161791 | - | 0.001709782 | 0.99829024 |
| ENST00000414447 | ENST00000493089 | PAX5 | chr9 | 36966545 | - | FOXP1 | chr3 | 71161791 | - | 0.017946793 | 0.98205316 |
| ENST00000414447 | ENST00000484350 | PAX5 | chr9 | 36966545 | - | FOXP1 | chr3 | 71161791 | - | 0.020157738 | 0.97984225 |
| ENST00000446742 | ENST00000318789 | PAX5 | chr9 | 36966545 | - | FOXP1 | chr3 | 71161791 | - | 0.001190429 | 0.9988096 |
| ENST00000446742 | ENST00000475937 | PAX5 | chr9 | 36966545 | - | FOXP1 | chr3 | 71161791 | - | 0.002951538 | 0.99704844 |
| ENST00000446742 | ENST00000493089 | PAX5 | chr9 | 36966545 | - | FOXP1 | chr3 | 71161791 | - | 0.017582443 | 0.9824175 |
| ENST00000446742 | ENST00000484350 | PAX5 | chr9 | 36966545 | - | FOXP1 | chr3 | 71161791 | - | 0.01880243 | 0.98119754 |
| ENST00000377847 | ENST00000318789 | PAX5 | chr9 | 36966545 | - | FOXP1 | chr3 | 71161791 | - | 0.000543042 | 0.99945694 |
| ENST00000377847 | ENST00000475937 | PAX5 | chr9 | 36966545 | - | FOXP1 | chr3 | 71161791 | - | 0.001449773 | 0.99855024 |
| ENST00000377847 | ENST00000493089 | PAX5 | chr9 | 36966545 | - | FOXP1 | chr3 | 71161791 | - | 0.014091144 | 0.9859088 |
| ENST00000377847 | ENST00000484350 | PAX5 | chr9 | 36966545 | - | FOXP1 | chr3 | 71161791 | - | 0.016983137 | 0.9830169 |
| ENST00000522003 | ENST00000318789 | PAX5 | chr9 | 37002645 | - | FOXP1 | chr3 | 71064806 | - | 0.000569102 | 0.99943084 |
| ENST00000522003 | ENST00000475937 | PAX5 | chr9 | 37002645 | - | FOXP1 | chr3 | 71064806 | - | 0.00114653 | 0.99885345 |
| ENST00000522003 | ENST00000493089 | PAX5 | chr9 | 37002645 | - | FOXP1 | chr3 | 71064806 | - | 0.011797995 | 0.98820204 |
| ENST00000522003 | ENST00000484350 | PAX5 | chr9 | 37002645 | - | FOXP1 | chr3 | 71064806 | - | 0.011102934 | 0.988897 |
| ENST00000523145 | ENST00000318789 | PAX5 | chr9 | 37002645 | - | FOXP1 | chr3 | 71064806 | - | 0.000569102 | 0.99943084 |
| ENST00000523145 | ENST00000475937 | PAX5 | chr9 | 37002645 | - | FOXP1 | chr3 | 71064806 | - | 0.00114653 | 0.99885345 |
| ENST00000523145 | ENST00000493089 | PAX5 | chr9 | 37002645 | - | FOXP1 | chr3 | 71064806 | - | 0.011797995 | 0.98820204 |
| ENST00000523145 | ENST00000484350 | PAX5 | chr9 | 37002645 | - | FOXP1 | chr3 | 71064806 | - | 0.011102934 | 0.988897 |
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Fusion Amino Acid Sequences |
| For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP >62950_62950_1_PAX5-FOXP1_PAX5_chr9_36966545_ENST00000358127_FOXP1_chr3_71161791_ENST00000318789_length(amino acids)=877AA_BP=259 MDLEKNYPTPRTSRTGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKV ATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIRTKVQQPPNQPVPASSHSIVSTGSVTQVSSVSTDSAGSSYS ISGILGITSPSADTNKRKRDEGIQESPVPNGHSLPGRDFLRKQMRGDLFTQQQLEVLDRVFERQHYSDIFTTTEPIKPEQALQVARQLLL QQQQQQQVSGLKSPKRNDKQPALQVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQVLLQQQQALMLQQQQLQEFYKKQQEQLQLQLLQ QQHAGKQPKEQQQVATQQLAFQQQLLQMQQLQQQHLLSLQRQGLLTIQPGQPALPLQPLAQGMIPTELQQLWKEVTSAHTAEETTGNNHS SLDLTTTCVSSSAPSKTSLIMNPHASTNGQLSVHTPKRESLSHEEHPHSHPLYGHGVCKWPGCEAVCEDFQSFLKHLNSEHALDDRSTAQ CRVQMQVVQQLELQLAKDKERLQAMMTHLHVKSTEPKAAPQPLNLVSSVTLSKSASEASPQSLPHTPTTPTAPLTPVTQGPSVITTTSMH TVGPIRRRYSDKYNVPISSADIAQNQEFYKNAEVRPPFTYASLIRQAILESPEKQLTLNEIYNWFTRMFAYFRRNAATWKNAVRHNLSLH KCFVRVENVKGAVWTVDEVEFQKRRPQKISGNPSLIKNMQSSHAYCTPLNAALQASMAENSIPLYTTASMGNPTLGNLASAIREELNGAM -------------------------------------------------------------- >62950_62950_2_PAX5-FOXP1_PAX5_chr9_36966545_ENST00000358127_FOXP1_chr3_71161791_ENST00000475937_length(amino acids)=877AA_BP=259 MDLEKNYPTPRTSRTGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKV ATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIRTKVQQPPNQPVPASSHSIVSTGSVTQVSSVSTDSAGSSYS ISGILGITSPSADTNKRKRDEGIQESPVPNGHSLPGRDFLRKQMRGDLFTQQQLEVLDRVFERQHYSDIFTTTEPIKPEQALQVARQLLL QQQQQQQVSGLKSPKRNDKQPALQVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQVLLQQQQALMLQQQQLQEFYKKQQEQLQLQLLQ QQHAGKQPKEQQQVATQQLAFQQQLLQMQQLQQQHLLSLQRQGLLTIQPGQPALPLQPLAQGMIPTELQQLWKEVTSAHTAEETTGNNHS SLDLTTTCVSSSAPSKTSLIMNPHASTNGQLSVHTPKRESLSHEEHPHSHPLYGHGVCKWPGCEAVCEDFQSFLKHLNSEHALDDRSTAQ CRVQMQVVQQLELQLAKDKERLQAMMTHLHVKSTEPKAAPQPLNLVSSVTLSKSASEASPQSLPHTPTTPTAPLTPVTQGPSVITTTSMH TVGPIRRRYSDKYNVPISSADIAQNQEFYKNAEVRPPFTYASLIRQAILESPEKQLTLNEIYNWFTRMFAYFRRNAATWKNAVRHNLSLH KCFVRVENVKGAVWTVDEVEFQKRRPQKISGNPSLIKNMQSSHAYCTPLNAALQASMAENSIPLYTTASMGNPTLGNLASAIREELNGAM -------------------------------------------------------------- >62950_62950_3_PAX5-FOXP1_PAX5_chr9_36966545_ENST00000358127_FOXP1_chr3_71161791_ENST00000484350_length(amino acids)=801AA_BP=259 MDLEKNYPTPRTSRTGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKV ATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIRTKVQQPPNQPVPASSHSIVSTGSVTQVSSVSTDSAGSSYS ISGILGITSPSADTNKRKRDEGIQESPVPNGHSLPGRDFLRKQMRGDLFTQQQLEVLDRVFERQHYSDIFTTTEPIKPEQALQVARQLLL QQQQQQQVSGLKSPKRNDKQPALQQQQVATQQLAFQQQLLQMQQLQQQHLLSLQRQGLLTIQPGQPALPLQPLAQGMIPTELQQLWKEVT SAHTAEETTGNNHSSLDLTTTCVSSSAPSKTSLIMNPHASTNGQLSVHTPKRESLSHEEHPHSHPLYGHGVCKWPGCEAVCEDFQSFLKH LNSEHALDDRSTAQCRVQMQVVQQLELQLAKDKERLQAMMTHLHVKSTEPKAAPQPLNLVSSVTLSKSASEASPQSLPHTPTTPTAPLTP VTQGPSVITTTSMHTVGPIRRRYSDKYNVPISSADIAQNQEFYKNAEVRPPFTYASLIRQAILESPEKQLTLNEIYNWFTRMFAYFRRNA ATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVEFQKRRPQKISGNPSLIKNMQSSHAYCTPLNAALQASMAENSIPLYTTASMGNPTLG -------------------------------------------------------------- >62950_62950_4_PAX5-FOXP1_PAX5_chr9_36966545_ENST00000358127_FOXP1_chr3_71161791_ENST00000493089_length(amino acids)=876AA_BP=259 MDLEKNYPTPRTSRTGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKV ATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIRTKVQQPPNQPVPASSHSIVSTGSVTQVSSVSTDSAGSSYS ISGILGITSPSADTNKRKRDEGIQESPVPNGHSLPGRDFLRKQMRGDLFTQQQLEVLDRVFERQHYSDIFTTTEPIKPEQALQVARQLLL QQQQQQQVSGLKSPKRNDKQPALQVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQVLLQQQQALMLQQQQLQEFYKKQQEQLQLQLLQ QQHAGKQPKEQQQVATQQLAFQQQLLQMQQLQQQHLLSLQRQGLLTIQPGQPALPLQPLAQGMIPTELQQLWKEVTSAHTAEETTGNNHS SLDLTTTCVSSSAPSKTSLIMNPHASTNGQLSVHTPKRESLSHEEHPHSHPLYGHGVCKWPGCEAVCEDFQSFLKHLNSEHALDDRSTAQ CRVQMQVVQQLELQLAKDKERLQAMMTHLHVKSTEPKAAPQPLNLVSSVTLSKSASEASPQSLPHTPTTPTAPLTPVTQGPSVITTTSMH TVGPIRRRYSDKYNVPISSDIAQNQEFYKNAEVRPPFTYASLIRQAILESPEKQLTLNEIYNWFTRMFAYFRRNAATWKNAVRHNLSLHK CFVRVENVKGAVWTVDEVEFQKRRPQKISGNPSLIKNMQSSHAYCTPLNAALQASMAENSIPLYTTASMGNPTLGNLASAIREELNGAME -------------------------------------------------------------- >62950_62950_5_PAX5-FOXP1_PAX5_chr9_36966545_ENST00000377847_FOXP1_chr3_71161791_ENST00000318789_length(amino acids)=877AA_BP=259 MDLEKNYPTPRTSRTGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKV ATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIRTKVQQPPNQPVPASSHSIVSTGSVTQVSSVSTDSAGSSYS ISGILGITSPSADTNKRKRDEGIQESPVPNGHSLPGRDFLRKQMRGDLFTQQQLEVLDRVFERQHYSDIFTTTEPIKPEQALQVARQLLL QQQQQQQVSGLKSPKRNDKQPALQVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQVLLQQQQALMLQQQQLQEFYKKQQEQLQLQLLQ QQHAGKQPKEQQQVATQQLAFQQQLLQMQQLQQQHLLSLQRQGLLTIQPGQPALPLQPLAQGMIPTELQQLWKEVTSAHTAEETTGNNHS SLDLTTTCVSSSAPSKTSLIMNPHASTNGQLSVHTPKRESLSHEEHPHSHPLYGHGVCKWPGCEAVCEDFQSFLKHLNSEHALDDRSTAQ CRVQMQVVQQLELQLAKDKERLQAMMTHLHVKSTEPKAAPQPLNLVSSVTLSKSASEASPQSLPHTPTTPTAPLTPVTQGPSVITTTSMH TVGPIRRRYSDKYNVPISSADIAQNQEFYKNAEVRPPFTYASLIRQAILESPEKQLTLNEIYNWFTRMFAYFRRNAATWKNAVRHNLSLH KCFVRVENVKGAVWTVDEVEFQKRRPQKISGNPSLIKNMQSSHAYCTPLNAALQASMAENSIPLYTTASMGNPTLGNLASAIREELNGAM -------------------------------------------------------------- >62950_62950_6_PAX5-FOXP1_PAX5_chr9_36966545_ENST00000377847_FOXP1_chr3_71161791_ENST00000475937_length(amino acids)=877AA_BP=259 MDLEKNYPTPRTSRTGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKV ATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIRTKVQQPPNQPVPASSHSIVSTGSVTQVSSVSTDSAGSSYS ISGILGITSPSADTNKRKRDEGIQESPVPNGHSLPGRDFLRKQMRGDLFTQQQLEVLDRVFERQHYSDIFTTTEPIKPEQALQVARQLLL QQQQQQQVSGLKSPKRNDKQPALQVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQVLLQQQQALMLQQQQLQEFYKKQQEQLQLQLLQ QQHAGKQPKEQQQVATQQLAFQQQLLQMQQLQQQHLLSLQRQGLLTIQPGQPALPLQPLAQGMIPTELQQLWKEVTSAHTAEETTGNNHS SLDLTTTCVSSSAPSKTSLIMNPHASTNGQLSVHTPKRESLSHEEHPHSHPLYGHGVCKWPGCEAVCEDFQSFLKHLNSEHALDDRSTAQ CRVQMQVVQQLELQLAKDKERLQAMMTHLHVKSTEPKAAPQPLNLVSSVTLSKSASEASPQSLPHTPTTPTAPLTPVTQGPSVITTTSMH TVGPIRRRYSDKYNVPISSADIAQNQEFYKNAEVRPPFTYASLIRQAILESPEKQLTLNEIYNWFTRMFAYFRRNAATWKNAVRHNLSLH KCFVRVENVKGAVWTVDEVEFQKRRPQKISGNPSLIKNMQSSHAYCTPLNAALQASMAENSIPLYTTASMGNPTLGNLASAIREELNGAM -------------------------------------------------------------- >62950_62950_7_PAX5-FOXP1_PAX5_chr9_36966545_ENST00000377847_FOXP1_chr3_71161791_ENST00000484350_length(amino acids)=801AA_BP=259 MDLEKNYPTPRTSRTGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKV ATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIRTKVQQPPNQPVPASSHSIVSTGSVTQVSSVSTDSAGSSYS ISGILGITSPSADTNKRKRDEGIQESPVPNGHSLPGRDFLRKQMRGDLFTQQQLEVLDRVFERQHYSDIFTTTEPIKPEQALQVARQLLL QQQQQQQVSGLKSPKRNDKQPALQQQQVATQQLAFQQQLLQMQQLQQQHLLSLQRQGLLTIQPGQPALPLQPLAQGMIPTELQQLWKEVT SAHTAEETTGNNHSSLDLTTTCVSSSAPSKTSLIMNPHASTNGQLSVHTPKRESLSHEEHPHSHPLYGHGVCKWPGCEAVCEDFQSFLKH LNSEHALDDRSTAQCRVQMQVVQQLELQLAKDKERLQAMMTHLHVKSTEPKAAPQPLNLVSSVTLSKSASEASPQSLPHTPTTPTAPLTP VTQGPSVITTTSMHTVGPIRRRYSDKYNVPISSADIAQNQEFYKNAEVRPPFTYASLIRQAILESPEKQLTLNEIYNWFTRMFAYFRRNA ATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVEFQKRRPQKISGNPSLIKNMQSSHAYCTPLNAALQASMAENSIPLYTTASMGNPTLG -------------------------------------------------------------- >62950_62950_8_PAX5-FOXP1_PAX5_chr9_36966545_ENST00000377847_FOXP1_chr3_71161791_ENST00000493089_length(amino acids)=876AA_BP=259 MDLEKNYPTPRTSRTGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKV ATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIRTKVQQPPNQPVPASSHSIVSTGSVTQVSSVSTDSAGSSYS ISGILGITSPSADTNKRKRDEGIQESPVPNGHSLPGRDFLRKQMRGDLFTQQQLEVLDRVFERQHYSDIFTTTEPIKPEQALQVARQLLL QQQQQQQVSGLKSPKRNDKQPALQVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQVLLQQQQALMLQQQQLQEFYKKQQEQLQLQLLQ QQHAGKQPKEQQQVATQQLAFQQQLLQMQQLQQQHLLSLQRQGLLTIQPGQPALPLQPLAQGMIPTELQQLWKEVTSAHTAEETTGNNHS SLDLTTTCVSSSAPSKTSLIMNPHASTNGQLSVHTPKRESLSHEEHPHSHPLYGHGVCKWPGCEAVCEDFQSFLKHLNSEHALDDRSTAQ CRVQMQVVQQLELQLAKDKERLQAMMTHLHVKSTEPKAAPQPLNLVSSVTLSKSASEASPQSLPHTPTTPTAPLTPVTQGPSVITTTSMH TVGPIRRRYSDKYNVPISSDIAQNQEFYKNAEVRPPFTYASLIRQAILESPEKQLTLNEIYNWFTRMFAYFRRNAATWKNAVRHNLSLHK CFVRVENVKGAVWTVDEVEFQKRRPQKISGNPSLIKNMQSSHAYCTPLNAALQASMAENSIPLYTTASMGNPTLGNLASAIREELNGAME -------------------------------------------------------------- >62950_62950_9_PAX5-FOXP1_PAX5_chr9_36966545_ENST00000377852_FOXP1_chr3_71161791_ENST00000318789_length(amino acids)=877AA_BP=259 MDLEKNYPTPRTSRTGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKV ATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIRTKVQQPPNQPVPASSHSIVSTGSVTQVSSVSTDSAGSSYS ISGILGITSPSADTNKRKRDEGIQESPVPNGHSLPGRDFLRKQMRGDLFTQQQLEVLDRVFERQHYSDIFTTTEPIKPEQALQVARQLLL QQQQQQQVSGLKSPKRNDKQPALQVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQVLLQQQQALMLQQQQLQEFYKKQQEQLQLQLLQ QQHAGKQPKEQQQVATQQLAFQQQLLQMQQLQQQHLLSLQRQGLLTIQPGQPALPLQPLAQGMIPTELQQLWKEVTSAHTAEETTGNNHS SLDLTTTCVSSSAPSKTSLIMNPHASTNGQLSVHTPKRESLSHEEHPHSHPLYGHGVCKWPGCEAVCEDFQSFLKHLNSEHALDDRSTAQ CRVQMQVVQQLELQLAKDKERLQAMMTHLHVKSTEPKAAPQPLNLVSSVTLSKSASEASPQSLPHTPTTPTAPLTPVTQGPSVITTTSMH TVGPIRRRYSDKYNVPISSADIAQNQEFYKNAEVRPPFTYASLIRQAILESPEKQLTLNEIYNWFTRMFAYFRRNAATWKNAVRHNLSLH KCFVRVENVKGAVWTVDEVEFQKRRPQKISGNPSLIKNMQSSHAYCTPLNAALQASMAENSIPLYTTASMGNPTLGNLASAIREELNGAM -------------------------------------------------------------- >62950_62950_10_PAX5-FOXP1_PAX5_chr9_36966545_ENST00000377852_FOXP1_chr3_71161791_ENST00000475937_length(amino acids)=877AA_BP=259 MDLEKNYPTPRTSRTGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKV ATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIRTKVQQPPNQPVPASSHSIVSTGSVTQVSSVSTDSAGSSYS ISGILGITSPSADTNKRKRDEGIQESPVPNGHSLPGRDFLRKQMRGDLFTQQQLEVLDRVFERQHYSDIFTTTEPIKPEQALQVARQLLL QQQQQQQVSGLKSPKRNDKQPALQVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQVLLQQQQALMLQQQQLQEFYKKQQEQLQLQLLQ QQHAGKQPKEQQQVATQQLAFQQQLLQMQQLQQQHLLSLQRQGLLTIQPGQPALPLQPLAQGMIPTELQQLWKEVTSAHTAEETTGNNHS SLDLTTTCVSSSAPSKTSLIMNPHASTNGQLSVHTPKRESLSHEEHPHSHPLYGHGVCKWPGCEAVCEDFQSFLKHLNSEHALDDRSTAQ CRVQMQVVQQLELQLAKDKERLQAMMTHLHVKSTEPKAAPQPLNLVSSVTLSKSASEASPQSLPHTPTTPTAPLTPVTQGPSVITTTSMH TVGPIRRRYSDKYNVPISSADIAQNQEFYKNAEVRPPFTYASLIRQAILESPEKQLTLNEIYNWFTRMFAYFRRNAATWKNAVRHNLSLH KCFVRVENVKGAVWTVDEVEFQKRRPQKISGNPSLIKNMQSSHAYCTPLNAALQASMAENSIPLYTTASMGNPTLGNLASAIREELNGAM -------------------------------------------------------------- >62950_62950_11_PAX5-FOXP1_PAX5_chr9_36966545_ENST00000377852_FOXP1_chr3_71161791_ENST00000484350_length(amino acids)=801AA_BP=259 MDLEKNYPTPRTSRTGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKV ATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIRTKVQQPPNQPVPASSHSIVSTGSVTQVSSVSTDSAGSSYS ISGILGITSPSADTNKRKRDEGIQESPVPNGHSLPGRDFLRKQMRGDLFTQQQLEVLDRVFERQHYSDIFTTTEPIKPEQALQVARQLLL QQQQQQQVSGLKSPKRNDKQPALQQQQVATQQLAFQQQLLQMQQLQQQHLLSLQRQGLLTIQPGQPALPLQPLAQGMIPTELQQLWKEVT SAHTAEETTGNNHSSLDLTTTCVSSSAPSKTSLIMNPHASTNGQLSVHTPKRESLSHEEHPHSHPLYGHGVCKWPGCEAVCEDFQSFLKH LNSEHALDDRSTAQCRVQMQVVQQLELQLAKDKERLQAMMTHLHVKSTEPKAAPQPLNLVSSVTLSKSASEASPQSLPHTPTTPTAPLTP VTQGPSVITTTSMHTVGPIRRRYSDKYNVPISSADIAQNQEFYKNAEVRPPFTYASLIRQAILESPEKQLTLNEIYNWFTRMFAYFRRNA ATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVEFQKRRPQKISGNPSLIKNMQSSHAYCTPLNAALQASMAENSIPLYTTASMGNPTLG -------------------------------------------------------------- >62950_62950_12_PAX5-FOXP1_PAX5_chr9_36966545_ENST00000377852_FOXP1_chr3_71161791_ENST00000493089_length(amino acids)=876AA_BP=259 MDLEKNYPTPRTSRTGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKV ATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIRTKVQQPPNQPVPASSHSIVSTGSVTQVSSVSTDSAGSSYS ISGILGITSPSADTNKRKRDEGIQESPVPNGHSLPGRDFLRKQMRGDLFTQQQLEVLDRVFERQHYSDIFTTTEPIKPEQALQVARQLLL QQQQQQQVSGLKSPKRNDKQPALQVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQVLLQQQQALMLQQQQLQEFYKKQQEQLQLQLLQ QQHAGKQPKEQQQVATQQLAFQQQLLQMQQLQQQHLLSLQRQGLLTIQPGQPALPLQPLAQGMIPTELQQLWKEVTSAHTAEETTGNNHS SLDLTTTCVSSSAPSKTSLIMNPHASTNGQLSVHTPKRESLSHEEHPHSHPLYGHGVCKWPGCEAVCEDFQSFLKHLNSEHALDDRSTAQ CRVQMQVVQQLELQLAKDKERLQAMMTHLHVKSTEPKAAPQPLNLVSSVTLSKSASEASPQSLPHTPTTPTAPLTPVTQGPSVITTTSMH TVGPIRRRYSDKYNVPISSDIAQNQEFYKNAEVRPPFTYASLIRQAILESPEKQLTLNEIYNWFTRMFAYFRRNAATWKNAVRHNLSLHK CFVRVENVKGAVWTVDEVEFQKRRPQKISGNPSLIKNMQSSHAYCTPLNAALQASMAENSIPLYTTASMGNPTLGNLASAIREELNGAME -------------------------------------------------------------- >62950_62950_13_PAX5-FOXP1_PAX5_chr9_36966545_ENST00000377853_FOXP1_chr3_71161791_ENST00000318789_length(amino acids)=877AA_BP=259 MDLEKNYPTPRTSRTGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKV ATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIRTKVQQPPNQPVPASSHSIVSTGSVTQVSSVSTDSAGSSYS ISGILGITSPSADTNKRKRDEGIQESPVPNGHSLPGRDFLRKQMRGDLFTQQQLEVLDRVFERQHYSDIFTTTEPIKPEQALQVARQLLL QQQQQQQVSGLKSPKRNDKQPALQVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQVLLQQQQALMLQQQQLQEFYKKQQEQLQLQLLQ QQHAGKQPKEQQQVATQQLAFQQQLLQMQQLQQQHLLSLQRQGLLTIQPGQPALPLQPLAQGMIPTELQQLWKEVTSAHTAEETTGNNHS SLDLTTTCVSSSAPSKTSLIMNPHASTNGQLSVHTPKRESLSHEEHPHSHPLYGHGVCKWPGCEAVCEDFQSFLKHLNSEHALDDRSTAQ CRVQMQVVQQLELQLAKDKERLQAMMTHLHVKSTEPKAAPQPLNLVSSVTLSKSASEASPQSLPHTPTTPTAPLTPVTQGPSVITTTSMH TVGPIRRRYSDKYNVPISSADIAQNQEFYKNAEVRPPFTYASLIRQAILESPEKQLTLNEIYNWFTRMFAYFRRNAATWKNAVRHNLSLH KCFVRVENVKGAVWTVDEVEFQKRRPQKISGNPSLIKNMQSSHAYCTPLNAALQASMAENSIPLYTTASMGNPTLGNLASAIREELNGAM -------------------------------------------------------------- >62950_62950_14_PAX5-FOXP1_PAX5_chr9_36966545_ENST00000377853_FOXP1_chr3_71161791_ENST00000475937_length(amino acids)=877AA_BP=259 MDLEKNYPTPRTSRTGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKV ATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIRTKVQQPPNQPVPASSHSIVSTGSVTQVSSVSTDSAGSSYS ISGILGITSPSADTNKRKRDEGIQESPVPNGHSLPGRDFLRKQMRGDLFTQQQLEVLDRVFERQHYSDIFTTTEPIKPEQALQVARQLLL QQQQQQQVSGLKSPKRNDKQPALQVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQVLLQQQQALMLQQQQLQEFYKKQQEQLQLQLLQ QQHAGKQPKEQQQVATQQLAFQQQLLQMQQLQQQHLLSLQRQGLLTIQPGQPALPLQPLAQGMIPTELQQLWKEVTSAHTAEETTGNNHS SLDLTTTCVSSSAPSKTSLIMNPHASTNGQLSVHTPKRESLSHEEHPHSHPLYGHGVCKWPGCEAVCEDFQSFLKHLNSEHALDDRSTAQ CRVQMQVVQQLELQLAKDKERLQAMMTHLHVKSTEPKAAPQPLNLVSSVTLSKSASEASPQSLPHTPTTPTAPLTPVTQGPSVITTTSMH TVGPIRRRYSDKYNVPISSADIAQNQEFYKNAEVRPPFTYASLIRQAILESPEKQLTLNEIYNWFTRMFAYFRRNAATWKNAVRHNLSLH KCFVRVENVKGAVWTVDEVEFQKRRPQKISGNPSLIKNMQSSHAYCTPLNAALQASMAENSIPLYTTASMGNPTLGNLASAIREELNGAM -------------------------------------------------------------- >62950_62950_15_PAX5-FOXP1_PAX5_chr9_36966545_ENST00000377853_FOXP1_chr3_71161791_ENST00000484350_length(amino acids)=801AA_BP=259 MDLEKNYPTPRTSRTGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKV ATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIRTKVQQPPNQPVPASSHSIVSTGSVTQVSSVSTDSAGSSYS ISGILGITSPSADTNKRKRDEGIQESPVPNGHSLPGRDFLRKQMRGDLFTQQQLEVLDRVFERQHYSDIFTTTEPIKPEQALQVARQLLL QQQQQQQVSGLKSPKRNDKQPALQQQQVATQQLAFQQQLLQMQQLQQQHLLSLQRQGLLTIQPGQPALPLQPLAQGMIPTELQQLWKEVT SAHTAEETTGNNHSSLDLTTTCVSSSAPSKTSLIMNPHASTNGQLSVHTPKRESLSHEEHPHSHPLYGHGVCKWPGCEAVCEDFQSFLKH LNSEHALDDRSTAQCRVQMQVVQQLELQLAKDKERLQAMMTHLHVKSTEPKAAPQPLNLVSSVTLSKSASEASPQSLPHTPTTPTAPLTP VTQGPSVITTTSMHTVGPIRRRYSDKYNVPISSADIAQNQEFYKNAEVRPPFTYASLIRQAILESPEKQLTLNEIYNWFTRMFAYFRRNA ATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVEFQKRRPQKISGNPSLIKNMQSSHAYCTPLNAALQASMAENSIPLYTTASMGNPTLG -------------------------------------------------------------- >62950_62950_16_PAX5-FOXP1_PAX5_chr9_36966545_ENST00000377853_FOXP1_chr3_71161791_ENST00000493089_length(amino acids)=876AA_BP=259 MDLEKNYPTPRTSRTGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKV ATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIRTKVQQPPNQPVPASSHSIVSTGSVTQVSSVSTDSAGSSYS ISGILGITSPSADTNKRKRDEGIQESPVPNGHSLPGRDFLRKQMRGDLFTQQQLEVLDRVFERQHYSDIFTTTEPIKPEQALQVARQLLL QQQQQQQVSGLKSPKRNDKQPALQVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQVLLQQQQALMLQQQQLQEFYKKQQEQLQLQLLQ QQHAGKQPKEQQQVATQQLAFQQQLLQMQQLQQQHLLSLQRQGLLTIQPGQPALPLQPLAQGMIPTELQQLWKEVTSAHTAEETTGNNHS SLDLTTTCVSSSAPSKTSLIMNPHASTNGQLSVHTPKRESLSHEEHPHSHPLYGHGVCKWPGCEAVCEDFQSFLKHLNSEHALDDRSTAQ CRVQMQVVQQLELQLAKDKERLQAMMTHLHVKSTEPKAAPQPLNLVSSVTLSKSASEASPQSLPHTPTTPTAPLTPVTQGPSVITTTSMH TVGPIRRRYSDKYNVPISSDIAQNQEFYKNAEVRPPFTYASLIRQAILESPEKQLTLNEIYNWFTRMFAYFRRNAATWKNAVRHNLSLHK CFVRVENVKGAVWTVDEVEFQKRRPQKISGNPSLIKNMQSSHAYCTPLNAALQASMAENSIPLYTTASMGNPTLGNLASAIREELNGAME -------------------------------------------------------------- >62950_62950_17_PAX5-FOXP1_PAX5_chr9_36966545_ENST00000414447_FOXP1_chr3_71161791_ENST00000318789_length(amino acids)=834AA_BP=216 MDLEKNYPTPRTSRTGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKV ATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIRTKVQQPPNQPVPASSHSIGIQESPVPNGHSLPGRDFLRKQ MRGDLFTQQQLEVLDRVFERQHYSDIFTTTEPIKPEQALQVARQLLLQQQQQQQVSGLKSPKRNDKQPALQVPVSVAMMTPQVITPQQMQ QILQQQVLSPQQLQVLLQQQQALMLQQQQLQEFYKKQQEQLQLQLLQQQHAGKQPKEQQQVATQQLAFQQQLLQMQQLQQQHLLSLQRQG LLTIQPGQPALPLQPLAQGMIPTELQQLWKEVTSAHTAEETTGNNHSSLDLTTTCVSSSAPSKTSLIMNPHASTNGQLSVHTPKRESLSH EEHPHSHPLYGHGVCKWPGCEAVCEDFQSFLKHLNSEHALDDRSTAQCRVQMQVVQQLELQLAKDKERLQAMMTHLHVKSTEPKAAPQPL NLVSSVTLSKSASEASPQSLPHTPTTPTAPLTPVTQGPSVITTTSMHTVGPIRRRYSDKYNVPISSADIAQNQEFYKNAEVRPPFTYASL IRQAILESPEKQLTLNEIYNWFTRMFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVEFQKRRPQKISGNPSLIKNMQSSH AYCTPLNAALQASMAENSIPLYTTASMGNPTLGNLASAIREELNGAMEHTNSNESDSSPGRSPMQAVHPVHVKEEPLDPEEAEGPLSLVT -------------------------------------------------------------- >62950_62950_18_PAX5-FOXP1_PAX5_chr9_36966545_ENST00000414447_FOXP1_chr3_71161791_ENST00000475937_length(amino acids)=834AA_BP=216 MDLEKNYPTPRTSRTGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKV ATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIRTKVQQPPNQPVPASSHSIGIQESPVPNGHSLPGRDFLRKQ MRGDLFTQQQLEVLDRVFERQHYSDIFTTTEPIKPEQALQVARQLLLQQQQQQQVSGLKSPKRNDKQPALQVPVSVAMMTPQVITPQQMQ QILQQQVLSPQQLQVLLQQQQALMLQQQQLQEFYKKQQEQLQLQLLQQQHAGKQPKEQQQVATQQLAFQQQLLQMQQLQQQHLLSLQRQG LLTIQPGQPALPLQPLAQGMIPTELQQLWKEVTSAHTAEETTGNNHSSLDLTTTCVSSSAPSKTSLIMNPHASTNGQLSVHTPKRESLSH EEHPHSHPLYGHGVCKWPGCEAVCEDFQSFLKHLNSEHALDDRSTAQCRVQMQVVQQLELQLAKDKERLQAMMTHLHVKSTEPKAAPQPL NLVSSVTLSKSASEASPQSLPHTPTTPTAPLTPVTQGPSVITTTSMHTVGPIRRRYSDKYNVPISSADIAQNQEFYKNAEVRPPFTYASL IRQAILESPEKQLTLNEIYNWFTRMFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVEFQKRRPQKISGNPSLIKNMQSSH AYCTPLNAALQASMAENSIPLYTTASMGNPTLGNLASAIREELNGAMEHTNSNESDSSPGRSPMQAVHPVHVKEEPLDPEEAEGPLSLVT -------------------------------------------------------------- >62950_62950_19_PAX5-FOXP1_PAX5_chr9_36966545_ENST00000414447_FOXP1_chr3_71161791_ENST00000484350_length(amino acids)=758AA_BP=216 MDLEKNYPTPRTSRTGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKV ATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIRTKVQQPPNQPVPASSHSIGIQESPVPNGHSLPGRDFLRKQ MRGDLFTQQQLEVLDRVFERQHYSDIFTTTEPIKPEQALQVARQLLLQQQQQQQVSGLKSPKRNDKQPALQQQQVATQQLAFQQQLLQMQ QLQQQHLLSLQRQGLLTIQPGQPALPLQPLAQGMIPTELQQLWKEVTSAHTAEETTGNNHSSLDLTTTCVSSSAPSKTSLIMNPHASTNG QLSVHTPKRESLSHEEHPHSHPLYGHGVCKWPGCEAVCEDFQSFLKHLNSEHALDDRSTAQCRVQMQVVQQLELQLAKDKERLQAMMTHL HVKSTEPKAAPQPLNLVSSVTLSKSASEASPQSLPHTPTTPTAPLTPVTQGPSVITTTSMHTVGPIRRRYSDKYNVPISSADIAQNQEFY KNAEVRPPFTYASLIRQAILESPEKQLTLNEIYNWFTRMFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVEFQKRRPQKI SGNPSLIKNMQSSHAYCTPLNAALQASMAENSIPLYTTASMGNPTLGNLASAIREELNGAMEHTNSNESDSSPGRSPMQAVHPVHVKEEP -------------------------------------------------------------- >62950_62950_20_PAX5-FOXP1_PAX5_chr9_36966545_ENST00000414447_FOXP1_chr3_71161791_ENST00000493089_length(amino acids)=833AA_BP=216 MDLEKNYPTPRTSRTGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKV ATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIRTKVQQPPNQPVPASSHSIGIQESPVPNGHSLPGRDFLRKQ MRGDLFTQQQLEVLDRVFERQHYSDIFTTTEPIKPEQALQVARQLLLQQQQQQQVSGLKSPKRNDKQPALQVPVSVAMMTPQVITPQQMQ QILQQQVLSPQQLQVLLQQQQALMLQQQQLQEFYKKQQEQLQLQLLQQQHAGKQPKEQQQVATQQLAFQQQLLQMQQLQQQHLLSLQRQG LLTIQPGQPALPLQPLAQGMIPTELQQLWKEVTSAHTAEETTGNNHSSLDLTTTCVSSSAPSKTSLIMNPHASTNGQLSVHTPKRESLSH EEHPHSHPLYGHGVCKWPGCEAVCEDFQSFLKHLNSEHALDDRSTAQCRVQMQVVQQLELQLAKDKERLQAMMTHLHVKSTEPKAAPQPL NLVSSVTLSKSASEASPQSLPHTPTTPTAPLTPVTQGPSVITTTSMHTVGPIRRRYSDKYNVPISSDIAQNQEFYKNAEVRPPFTYASLI RQAILESPEKQLTLNEIYNWFTRMFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVEFQKRRPQKISGNPSLIKNMQSSHA YCTPLNAALQASMAENSIPLYTTASMGNPTLGNLASAIREELNGAMEHTNSNESDSSPGRSPMQAVHPVHVKEEPLDPEEAEGPLSLVTT -------------------------------------------------------------- >62950_62950_21_PAX5-FOXP1_PAX5_chr9_36966545_ENST00000446742_FOXP1_chr3_71161791_ENST00000318789_length(amino acids)=811AA_BP=193 MDLEKNYPTPRTSRTGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRIIRTKVQQPPNQPVPASSH SIVSTGSVTQVSSVSTDSAGSSYSISGILGITSPSADTNKRKRDEGIQESPVPNGHSLPGRDFLRKQMRGDLFTQQQLEVLDRVFERQHY SDIFTTTEPIKPEQALQVARQLLLQQQQQQQVSGLKSPKRNDKQPALQVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQVLLQQQQAL MLQQQQLQEFYKKQQEQLQLQLLQQQHAGKQPKEQQQVATQQLAFQQQLLQMQQLQQQHLLSLQRQGLLTIQPGQPALPLQPLAQGMIPT ELQQLWKEVTSAHTAEETTGNNHSSLDLTTTCVSSSAPSKTSLIMNPHASTNGQLSVHTPKRESLSHEEHPHSHPLYGHGVCKWPGCEAV CEDFQSFLKHLNSEHALDDRSTAQCRVQMQVVQQLELQLAKDKERLQAMMTHLHVKSTEPKAAPQPLNLVSSVTLSKSASEASPQSLPHT PTTPTAPLTPVTQGPSVITTTSMHTVGPIRRRYSDKYNVPISSADIAQNQEFYKNAEVRPPFTYASLIRQAILESPEKQLTLNEIYNWFT RMFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVEFQKRRPQKISGNPSLIKNMQSSHAYCTPLNAALQASMAENSIPLYT TASMGNPTLGNLASAIREELNGAMEHTNSNESDSSPGRSPMQAVHPVHVKEEPLDPEEAEGPLSLVTTANHSPDFDHDRDYEDEPVNEDM -------------------------------------------------------------- >62950_62950_22_PAX5-FOXP1_PAX5_chr9_36966545_ENST00000446742_FOXP1_chr3_71161791_ENST00000475937_length(amino acids)=811AA_BP=193 MDLEKNYPTPRTSRTGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRIIRTKVQQPPNQPVPASSH SIVSTGSVTQVSSVSTDSAGSSYSISGILGITSPSADTNKRKRDEGIQESPVPNGHSLPGRDFLRKQMRGDLFTQQQLEVLDRVFERQHY SDIFTTTEPIKPEQALQVARQLLLQQQQQQQVSGLKSPKRNDKQPALQVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQVLLQQQQAL MLQQQQLQEFYKKQQEQLQLQLLQQQHAGKQPKEQQQVATQQLAFQQQLLQMQQLQQQHLLSLQRQGLLTIQPGQPALPLQPLAQGMIPT ELQQLWKEVTSAHTAEETTGNNHSSLDLTTTCVSSSAPSKTSLIMNPHASTNGQLSVHTPKRESLSHEEHPHSHPLYGHGVCKWPGCEAV CEDFQSFLKHLNSEHALDDRSTAQCRVQMQVVQQLELQLAKDKERLQAMMTHLHVKSTEPKAAPQPLNLVSSVTLSKSASEASPQSLPHT PTTPTAPLTPVTQGPSVITTTSMHTVGPIRRRYSDKYNVPISSADIAQNQEFYKNAEVRPPFTYASLIRQAILESPEKQLTLNEIYNWFT RMFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVEFQKRRPQKISGNPSLIKNMQSSHAYCTPLNAALQASMAENSIPLYT TASMGNPTLGNLASAIREELNGAMEHTNSNESDSSPGRSPMQAVHPVHVKEEPLDPEEAEGPLSLVTTANHSPDFDHDRDYEDEPVNEDM -------------------------------------------------------------- >62950_62950_23_PAX5-FOXP1_PAX5_chr9_36966545_ENST00000446742_FOXP1_chr3_71161791_ENST00000484350_length(amino acids)=735AA_BP=193 MDLEKNYPTPRTSRTGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRIIRTKVQQPPNQPVPASSH SIVSTGSVTQVSSVSTDSAGSSYSISGILGITSPSADTNKRKRDEGIQESPVPNGHSLPGRDFLRKQMRGDLFTQQQLEVLDRVFERQHY SDIFTTTEPIKPEQALQVARQLLLQQQQQQQVSGLKSPKRNDKQPALQQQQVATQQLAFQQQLLQMQQLQQQHLLSLQRQGLLTIQPGQP ALPLQPLAQGMIPTELQQLWKEVTSAHTAEETTGNNHSSLDLTTTCVSSSAPSKTSLIMNPHASTNGQLSVHTPKRESLSHEEHPHSHPL YGHGVCKWPGCEAVCEDFQSFLKHLNSEHALDDRSTAQCRVQMQVVQQLELQLAKDKERLQAMMTHLHVKSTEPKAAPQPLNLVSSVTLS KSASEASPQSLPHTPTTPTAPLTPVTQGPSVITTTSMHTVGPIRRRYSDKYNVPISSADIAQNQEFYKNAEVRPPFTYASLIRQAILESP EKQLTLNEIYNWFTRMFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVEFQKRRPQKISGNPSLIKNMQSSHAYCTPLNAA LQASMAENSIPLYTTASMGNPTLGNLASAIREELNGAMEHTNSNESDSSPGRSPMQAVHPVHVKEEPLDPEEAEGPLSLVTTANHSPDFD -------------------------------------------------------------- >62950_62950_24_PAX5-FOXP1_PAX5_chr9_36966545_ENST00000446742_FOXP1_chr3_71161791_ENST00000493089_length(amino acids)=810AA_BP=193 MDLEKNYPTPRTSRTGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRIIRTKVQQPPNQPVPASSH SIVSTGSVTQVSSVSTDSAGSSYSISGILGITSPSADTNKRKRDEGIQESPVPNGHSLPGRDFLRKQMRGDLFTQQQLEVLDRVFERQHY SDIFTTTEPIKPEQALQVARQLLLQQQQQQQVSGLKSPKRNDKQPALQVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQVLLQQQQAL MLQQQQLQEFYKKQQEQLQLQLLQQQHAGKQPKEQQQVATQQLAFQQQLLQMQQLQQQHLLSLQRQGLLTIQPGQPALPLQPLAQGMIPT ELQQLWKEVTSAHTAEETTGNNHSSLDLTTTCVSSSAPSKTSLIMNPHASTNGQLSVHTPKRESLSHEEHPHSHPLYGHGVCKWPGCEAV CEDFQSFLKHLNSEHALDDRSTAQCRVQMQVVQQLELQLAKDKERLQAMMTHLHVKSTEPKAAPQPLNLVSSVTLSKSASEASPQSLPHT PTTPTAPLTPVTQGPSVITTTSMHTVGPIRRRYSDKYNVPISSDIAQNQEFYKNAEVRPPFTYASLIRQAILESPEKQLTLNEIYNWFTR MFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVEFQKRRPQKISGNPSLIKNMQSSHAYCTPLNAALQASMAENSIPLYTT ASMGNPTLGNLASAIREELNGAMEHTNSNESDSSPGRSPMQAVHPVHVKEEPLDPEEAEGPLSLVTTANHSPDFDHDRDYEDEPVNEDME -------------------------------------------------------------- >62950_62950_25_PAX5-FOXP1_PAX5_chr9_36966545_ENST00000520154_FOXP1_chr3_71161791_ENST00000318789_length(amino acids)=877AA_BP=259 MDLEKNYPTPRTSRTGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKV ATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIRTKVQQPPNQPVPASSHSIVSTGSVTQVSSVSTDSAGSSYS ISGILGITSPSADTNKRKRDEGIQESPVPNGHSLPGRDFLRKQMRGDLFTQQQLEVLDRVFERQHYSDIFTTTEPIKPEQALQVARQLLL QQQQQQQVSGLKSPKRNDKQPALQVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQVLLQQQQALMLQQQQLQEFYKKQQEQLQLQLLQ QQHAGKQPKEQQQVATQQLAFQQQLLQMQQLQQQHLLSLQRQGLLTIQPGQPALPLQPLAQGMIPTELQQLWKEVTSAHTAEETTGNNHS SLDLTTTCVSSSAPSKTSLIMNPHASTNGQLSVHTPKRESLSHEEHPHSHPLYGHGVCKWPGCEAVCEDFQSFLKHLNSEHALDDRSTAQ CRVQMQVVQQLELQLAKDKERLQAMMTHLHVKSTEPKAAPQPLNLVSSVTLSKSASEASPQSLPHTPTTPTAPLTPVTQGPSVITTTSMH TVGPIRRRYSDKYNVPISSADIAQNQEFYKNAEVRPPFTYASLIRQAILESPEKQLTLNEIYNWFTRMFAYFRRNAATWKNAVRHNLSLH KCFVRVENVKGAVWTVDEVEFQKRRPQKISGNPSLIKNMQSSHAYCTPLNAALQASMAENSIPLYTTASMGNPTLGNLASAIREELNGAM -------------------------------------------------------------- >62950_62950_26_PAX5-FOXP1_PAX5_chr9_36966545_ENST00000520154_FOXP1_chr3_71161791_ENST00000475937_length(amino acids)=877AA_BP=259 MDLEKNYPTPRTSRTGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKV ATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIRTKVQQPPNQPVPASSHSIVSTGSVTQVSSVSTDSAGSSYS ISGILGITSPSADTNKRKRDEGIQESPVPNGHSLPGRDFLRKQMRGDLFTQQQLEVLDRVFERQHYSDIFTTTEPIKPEQALQVARQLLL QQQQQQQVSGLKSPKRNDKQPALQVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQVLLQQQQALMLQQQQLQEFYKKQQEQLQLQLLQ QQHAGKQPKEQQQVATQQLAFQQQLLQMQQLQQQHLLSLQRQGLLTIQPGQPALPLQPLAQGMIPTELQQLWKEVTSAHTAEETTGNNHS SLDLTTTCVSSSAPSKTSLIMNPHASTNGQLSVHTPKRESLSHEEHPHSHPLYGHGVCKWPGCEAVCEDFQSFLKHLNSEHALDDRSTAQ CRVQMQVVQQLELQLAKDKERLQAMMTHLHVKSTEPKAAPQPLNLVSSVTLSKSASEASPQSLPHTPTTPTAPLTPVTQGPSVITTTSMH TVGPIRRRYSDKYNVPISSADIAQNQEFYKNAEVRPPFTYASLIRQAILESPEKQLTLNEIYNWFTRMFAYFRRNAATWKNAVRHNLSLH KCFVRVENVKGAVWTVDEVEFQKRRPQKISGNPSLIKNMQSSHAYCTPLNAALQASMAENSIPLYTTASMGNPTLGNLASAIREELNGAM -------------------------------------------------------------- >62950_62950_27_PAX5-FOXP1_PAX5_chr9_36966545_ENST00000520154_FOXP1_chr3_71161791_ENST00000484350_length(amino acids)=801AA_BP=259 MDLEKNYPTPRTSRTGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKV ATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIRTKVQQPPNQPVPASSHSIVSTGSVTQVSSVSTDSAGSSYS ISGILGITSPSADTNKRKRDEGIQESPVPNGHSLPGRDFLRKQMRGDLFTQQQLEVLDRVFERQHYSDIFTTTEPIKPEQALQVARQLLL QQQQQQQVSGLKSPKRNDKQPALQQQQVATQQLAFQQQLLQMQQLQQQHLLSLQRQGLLTIQPGQPALPLQPLAQGMIPTELQQLWKEVT SAHTAEETTGNNHSSLDLTTTCVSSSAPSKTSLIMNPHASTNGQLSVHTPKRESLSHEEHPHSHPLYGHGVCKWPGCEAVCEDFQSFLKH LNSEHALDDRSTAQCRVQMQVVQQLELQLAKDKERLQAMMTHLHVKSTEPKAAPQPLNLVSSVTLSKSASEASPQSLPHTPTTPTAPLTP VTQGPSVITTTSMHTVGPIRRRYSDKYNVPISSADIAQNQEFYKNAEVRPPFTYASLIRQAILESPEKQLTLNEIYNWFTRMFAYFRRNA ATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVEFQKRRPQKISGNPSLIKNMQSSHAYCTPLNAALQASMAENSIPLYTTASMGNPTLG -------------------------------------------------------------- >62950_62950_28_PAX5-FOXP1_PAX5_chr9_36966545_ENST00000520154_FOXP1_chr3_71161791_ENST00000493089_length(amino acids)=876AA_BP=259 MDLEKNYPTPRTSRTGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKV ATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIRTKVQQPPNQPVPASSHSIVSTGSVTQVSSVSTDSAGSSYS ISGILGITSPSADTNKRKRDEGIQESPVPNGHSLPGRDFLRKQMRGDLFTQQQLEVLDRVFERQHYSDIFTTTEPIKPEQALQVARQLLL QQQQQQQVSGLKSPKRNDKQPALQVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQVLLQQQQALMLQQQQLQEFYKKQQEQLQLQLLQ QQHAGKQPKEQQQVATQQLAFQQQLLQMQQLQQQHLLSLQRQGLLTIQPGQPALPLQPLAQGMIPTELQQLWKEVTSAHTAEETTGNNHS SLDLTTTCVSSSAPSKTSLIMNPHASTNGQLSVHTPKRESLSHEEHPHSHPLYGHGVCKWPGCEAVCEDFQSFLKHLNSEHALDDRSTAQ CRVQMQVVQQLELQLAKDKERLQAMMTHLHVKSTEPKAAPQPLNLVSSVTLSKSASEASPQSLPHTPTTPTAPLTPVTQGPSVITTTSMH TVGPIRRRYSDKYNVPISSDIAQNQEFYKNAEVRPPFTYASLIRQAILESPEKQLTLNEIYNWFTRMFAYFRRNAATWKNAVRHNLSLHK CFVRVENVKGAVWTVDEVEFQKRRPQKISGNPSLIKNMQSSHAYCTPLNAALQASMAENSIPLYTTASMGNPTLGNLASAIREELNGAME -------------------------------------------------------------- >62950_62950_29_PAX5-FOXP1_PAX5_chr9_36966545_ENST00000520281_FOXP1_chr3_71161791_ENST00000318789_length(amino acids)=834AA_BP=216 MDLEKNYPTPRTSRTGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKV ATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIRTKVQQPPNQPVPASSHSIGIQESPVPNGHSLPGRDFLRKQ MRGDLFTQQQLEVLDRVFERQHYSDIFTTTEPIKPEQALQVARQLLLQQQQQQQVSGLKSPKRNDKQPALQVPVSVAMMTPQVITPQQMQ QILQQQVLSPQQLQVLLQQQQALMLQQQQLQEFYKKQQEQLQLQLLQQQHAGKQPKEQQQVATQQLAFQQQLLQMQQLQQQHLLSLQRQG LLTIQPGQPALPLQPLAQGMIPTELQQLWKEVTSAHTAEETTGNNHSSLDLTTTCVSSSAPSKTSLIMNPHASTNGQLSVHTPKRESLSH EEHPHSHPLYGHGVCKWPGCEAVCEDFQSFLKHLNSEHALDDRSTAQCRVQMQVVQQLELQLAKDKERLQAMMTHLHVKSTEPKAAPQPL NLVSSVTLSKSASEASPQSLPHTPTTPTAPLTPVTQGPSVITTTSMHTVGPIRRRYSDKYNVPISSADIAQNQEFYKNAEVRPPFTYASL IRQAILESPEKQLTLNEIYNWFTRMFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVEFQKRRPQKISGNPSLIKNMQSSH AYCTPLNAALQASMAENSIPLYTTASMGNPTLGNLASAIREELNGAMEHTNSNESDSSPGRSPMQAVHPVHVKEEPLDPEEAEGPLSLVT -------------------------------------------------------------- >62950_62950_30_PAX5-FOXP1_PAX5_chr9_36966545_ENST00000520281_FOXP1_chr3_71161791_ENST00000475937_length(amino acids)=834AA_BP=216 MDLEKNYPTPRTSRTGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKV ATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIRTKVQQPPNQPVPASSHSIGIQESPVPNGHSLPGRDFLRKQ MRGDLFTQQQLEVLDRVFERQHYSDIFTTTEPIKPEQALQVARQLLLQQQQQQQVSGLKSPKRNDKQPALQVPVSVAMMTPQVITPQQMQ QILQQQVLSPQQLQVLLQQQQALMLQQQQLQEFYKKQQEQLQLQLLQQQHAGKQPKEQQQVATQQLAFQQQLLQMQQLQQQHLLSLQRQG LLTIQPGQPALPLQPLAQGMIPTELQQLWKEVTSAHTAEETTGNNHSSLDLTTTCVSSSAPSKTSLIMNPHASTNGQLSVHTPKRESLSH EEHPHSHPLYGHGVCKWPGCEAVCEDFQSFLKHLNSEHALDDRSTAQCRVQMQVVQQLELQLAKDKERLQAMMTHLHVKSTEPKAAPQPL NLVSSVTLSKSASEASPQSLPHTPTTPTAPLTPVTQGPSVITTTSMHTVGPIRRRYSDKYNVPISSADIAQNQEFYKNAEVRPPFTYASL IRQAILESPEKQLTLNEIYNWFTRMFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVEFQKRRPQKISGNPSLIKNMQSSH AYCTPLNAALQASMAENSIPLYTTASMGNPTLGNLASAIREELNGAMEHTNSNESDSSPGRSPMQAVHPVHVKEEPLDPEEAEGPLSLVT -------------------------------------------------------------- >62950_62950_31_PAX5-FOXP1_PAX5_chr9_36966545_ENST00000520281_FOXP1_chr3_71161791_ENST00000484350_length(amino acids)=758AA_BP=216 MDLEKNYPTPRTSRTGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKV ATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIRTKVQQPPNQPVPASSHSIGIQESPVPNGHSLPGRDFLRKQ MRGDLFTQQQLEVLDRVFERQHYSDIFTTTEPIKPEQALQVARQLLLQQQQQQQVSGLKSPKRNDKQPALQQQQVATQQLAFQQQLLQMQ QLQQQHLLSLQRQGLLTIQPGQPALPLQPLAQGMIPTELQQLWKEVTSAHTAEETTGNNHSSLDLTTTCVSSSAPSKTSLIMNPHASTNG QLSVHTPKRESLSHEEHPHSHPLYGHGVCKWPGCEAVCEDFQSFLKHLNSEHALDDRSTAQCRVQMQVVQQLELQLAKDKERLQAMMTHL HVKSTEPKAAPQPLNLVSSVTLSKSASEASPQSLPHTPTTPTAPLTPVTQGPSVITTTSMHTVGPIRRRYSDKYNVPISSADIAQNQEFY KNAEVRPPFTYASLIRQAILESPEKQLTLNEIYNWFTRMFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVEFQKRRPQKI SGNPSLIKNMQSSHAYCTPLNAALQASMAENSIPLYTTASMGNPTLGNLASAIREELNGAMEHTNSNESDSSPGRSPMQAVHPVHVKEEP -------------------------------------------------------------- >62950_62950_32_PAX5-FOXP1_PAX5_chr9_36966545_ENST00000520281_FOXP1_chr3_71161791_ENST00000493089_length(amino acids)=833AA_BP=216 MDLEKNYPTPRTSRTGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKV ATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIRTKVQQPPNQPVPASSHSIGIQESPVPNGHSLPGRDFLRKQ MRGDLFTQQQLEVLDRVFERQHYSDIFTTTEPIKPEQALQVARQLLLQQQQQQQVSGLKSPKRNDKQPALQVPVSVAMMTPQVITPQQMQ QILQQQVLSPQQLQVLLQQQQALMLQQQQLQEFYKKQQEQLQLQLLQQQHAGKQPKEQQQVATQQLAFQQQLLQMQQLQQQHLLSLQRQG LLTIQPGQPALPLQPLAQGMIPTELQQLWKEVTSAHTAEETTGNNHSSLDLTTTCVSSSAPSKTSLIMNPHASTNGQLSVHTPKRESLSH EEHPHSHPLYGHGVCKWPGCEAVCEDFQSFLKHLNSEHALDDRSTAQCRVQMQVVQQLELQLAKDKERLQAMMTHLHVKSTEPKAAPQPL NLVSSVTLSKSASEASPQSLPHTPTTPTAPLTPVTQGPSVITTTSMHTVGPIRRRYSDKYNVPISSDIAQNQEFYKNAEVRPPFTYASLI RQAILESPEKQLTLNEIYNWFTRMFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVEFQKRRPQKISGNPSLIKNMQSSHA YCTPLNAALQASMAENSIPLYTTASMGNPTLGNLASAIREELNGAMEHTNSNESDSSPGRSPMQAVHPVHVKEEPLDPEEAEGPLSLVTT -------------------------------------------------------------- >62950_62950_33_PAX5-FOXP1_PAX5_chr9_36966545_ENST00000523241_FOXP1_chr3_71161791_ENST00000318789_length(amino acids)=877AA_BP=259 MDLEKNYPTPRTSRTGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKV ATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIRTKVQQPPNQPVPASSHSIVSTGSVTQVSSVSTDSAGSSYS ISGILGITSPSADTNKRKRDEGIQESPVPNGHSLPGRDFLRKQMRGDLFTQQQLEVLDRVFERQHYSDIFTTTEPIKPEQALQVARQLLL QQQQQQQVSGLKSPKRNDKQPALQVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQVLLQQQQALMLQQQQLQEFYKKQQEQLQLQLLQ QQHAGKQPKEQQQVATQQLAFQQQLLQMQQLQQQHLLSLQRQGLLTIQPGQPALPLQPLAQGMIPTELQQLWKEVTSAHTAEETTGNNHS SLDLTTTCVSSSAPSKTSLIMNPHASTNGQLSVHTPKRESLSHEEHPHSHPLYGHGVCKWPGCEAVCEDFQSFLKHLNSEHALDDRSTAQ CRVQMQVVQQLELQLAKDKERLQAMMTHLHVKSTEPKAAPQPLNLVSSVTLSKSASEASPQSLPHTPTTPTAPLTPVTQGPSVITTTSMH TVGPIRRRYSDKYNVPISSADIAQNQEFYKNAEVRPPFTYASLIRQAILESPEKQLTLNEIYNWFTRMFAYFRRNAATWKNAVRHNLSLH KCFVRVENVKGAVWTVDEVEFQKRRPQKISGNPSLIKNMQSSHAYCTPLNAALQASMAENSIPLYTTASMGNPTLGNLASAIREELNGAM -------------------------------------------------------------- >62950_62950_34_PAX5-FOXP1_PAX5_chr9_36966545_ENST00000523241_FOXP1_chr3_71161791_ENST00000475937_length(amino acids)=877AA_BP=259 MDLEKNYPTPRTSRTGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKV ATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIRTKVQQPPNQPVPASSHSIVSTGSVTQVSSVSTDSAGSSYS ISGILGITSPSADTNKRKRDEGIQESPVPNGHSLPGRDFLRKQMRGDLFTQQQLEVLDRVFERQHYSDIFTTTEPIKPEQALQVARQLLL QQQQQQQVSGLKSPKRNDKQPALQVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQVLLQQQQALMLQQQQLQEFYKKQQEQLQLQLLQ QQHAGKQPKEQQQVATQQLAFQQQLLQMQQLQQQHLLSLQRQGLLTIQPGQPALPLQPLAQGMIPTELQQLWKEVTSAHTAEETTGNNHS SLDLTTTCVSSSAPSKTSLIMNPHASTNGQLSVHTPKRESLSHEEHPHSHPLYGHGVCKWPGCEAVCEDFQSFLKHLNSEHALDDRSTAQ CRVQMQVVQQLELQLAKDKERLQAMMTHLHVKSTEPKAAPQPLNLVSSVTLSKSASEASPQSLPHTPTTPTAPLTPVTQGPSVITTTSMH TVGPIRRRYSDKYNVPISSADIAQNQEFYKNAEVRPPFTYASLIRQAILESPEKQLTLNEIYNWFTRMFAYFRRNAATWKNAVRHNLSLH KCFVRVENVKGAVWTVDEVEFQKRRPQKISGNPSLIKNMQSSHAYCTPLNAALQASMAENSIPLYTTASMGNPTLGNLASAIREELNGAM -------------------------------------------------------------- >62950_62950_35_PAX5-FOXP1_PAX5_chr9_36966545_ENST00000523241_FOXP1_chr3_71161791_ENST00000484350_length(amino acids)=801AA_BP=259 MDLEKNYPTPRTSRTGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKV ATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIRTKVQQPPNQPVPASSHSIVSTGSVTQVSSVSTDSAGSSYS ISGILGITSPSADTNKRKRDEGIQESPVPNGHSLPGRDFLRKQMRGDLFTQQQLEVLDRVFERQHYSDIFTTTEPIKPEQALQVARQLLL QQQQQQQVSGLKSPKRNDKQPALQQQQVATQQLAFQQQLLQMQQLQQQHLLSLQRQGLLTIQPGQPALPLQPLAQGMIPTELQQLWKEVT SAHTAEETTGNNHSSLDLTTTCVSSSAPSKTSLIMNPHASTNGQLSVHTPKRESLSHEEHPHSHPLYGHGVCKWPGCEAVCEDFQSFLKH LNSEHALDDRSTAQCRVQMQVVQQLELQLAKDKERLQAMMTHLHVKSTEPKAAPQPLNLVSSVTLSKSASEASPQSLPHTPTTPTAPLTP VTQGPSVITTTSMHTVGPIRRRYSDKYNVPISSADIAQNQEFYKNAEVRPPFTYASLIRQAILESPEKQLTLNEIYNWFTRMFAYFRRNA ATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVEFQKRRPQKISGNPSLIKNMQSSHAYCTPLNAALQASMAENSIPLYTTASMGNPTLG -------------------------------------------------------------- >62950_62950_36_PAX5-FOXP1_PAX5_chr9_36966545_ENST00000523241_FOXP1_chr3_71161791_ENST00000493089_length(amino acids)=876AA_BP=259 MDLEKNYPTPRTSRTGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKV ATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIRTKVQQPPNQPVPASSHSIVSTGSVTQVSSVSTDSAGSSYS ISGILGITSPSADTNKRKRDEGIQESPVPNGHSLPGRDFLRKQMRGDLFTQQQLEVLDRVFERQHYSDIFTTTEPIKPEQALQVARQLLL QQQQQQQVSGLKSPKRNDKQPALQVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQVLLQQQQALMLQQQQLQEFYKKQQEQLQLQLLQ QQHAGKQPKEQQQVATQQLAFQQQLLQMQQLQQQHLLSLQRQGLLTIQPGQPALPLQPLAQGMIPTELQQLWKEVTSAHTAEETTGNNHS SLDLTTTCVSSSAPSKTSLIMNPHASTNGQLSVHTPKRESLSHEEHPHSHPLYGHGVCKWPGCEAVCEDFQSFLKHLNSEHALDDRSTAQ CRVQMQVVQQLELQLAKDKERLQAMMTHLHVKSTEPKAAPQPLNLVSSVTLSKSASEASPQSLPHTPTTPTAPLTPVTQGPSVITTTSMH TVGPIRRRYSDKYNVPISSDIAQNQEFYKNAEVRPPFTYASLIRQAILESPEKQLTLNEIYNWFTRMFAYFRRNAATWKNAVRHNLSLHK CFVRVENVKGAVWTVDEVEFQKRRPQKISGNPSLIKNMQSSHAYCTPLNAALQASMAENSIPLYTTASMGNPTLGNLASAIREELNGAME -------------------------------------------------------------- >62950_62950_37_PAX5-FOXP1_PAX5_chr9_37002645_ENST00000522003_FOXP1_chr3_71064806_ENST00000318789_length(amino acids)=387AA_BP=1 MSHEEHPHSHPLYGHGVCKWPGCEAVCEDFQSFLKHLNSEHALDDRSTAQCRVQMQVVQQLELQLAKDKERLQAMMTHLHVKSTEPKAAP QPLNLVSSVTLSKSASEASPQSLPHTPTTPTAPLTPVTQGPSVITTTSMHTVGPIRRRYSDKYNVPISSADIAQNQEFYKNAEVRPPFTY ASLIRQAILESPEKQLTLNEIYNWFTRMFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVEFQKRRPQKISGNPSLIKNMQ SSHAYCTPLNAALQASMAENSIPLYTTASMGNPTLGNLASAIREELNGAMEHTNSNESDSSPGRSPMQAVHPVHVKEEPLDPEEAEGPLS -------------------------------------------------------------- >62950_62950_38_PAX5-FOXP1_PAX5_chr9_37002645_ENST00000522003_FOXP1_chr3_71064806_ENST00000475937_length(amino acids)=387AA_BP=1 MSHEEHPHSHPLYGHGVCKWPGCEAVCEDFQSFLKHLNSEHALDDRSTAQCRVQMQVVQQLELQLAKDKERLQAMMTHLHVKSTEPKAAP QPLNLVSSVTLSKSASEASPQSLPHTPTTPTAPLTPVTQGPSVITTTSMHTVGPIRRRYSDKYNVPISSADIAQNQEFYKNAEVRPPFTY ASLIRQAILESPEKQLTLNEIYNWFTRMFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVEFQKRRPQKISGNPSLIKNMQ SSHAYCTPLNAALQASMAENSIPLYTTASMGNPTLGNLASAIREELNGAMEHTNSNESDSSPGRSPMQAVHPVHVKEEPLDPEEAEGPLS -------------------------------------------------------------- >62950_62950_39_PAX5-FOXP1_PAX5_chr9_37002645_ENST00000522003_FOXP1_chr3_71064806_ENST00000484350_length(amino acids)=387AA_BP=1 MSHEEHPHSHPLYGHGVCKWPGCEAVCEDFQSFLKHLNSEHALDDRSTAQCRVQMQVVQQLELQLAKDKERLQAMMTHLHVKSTEPKAAP QPLNLVSSVTLSKSASEASPQSLPHTPTTPTAPLTPVTQGPSVITTTSMHTVGPIRRRYSDKYNVPISSADIAQNQEFYKNAEVRPPFTY ASLIRQAILESPEKQLTLNEIYNWFTRMFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVEFQKRRPQKISGNPSLIKNMQ SSHAYCTPLNAALQASMAENSIPLYTTASMGNPTLGNLASAIREELNGAMEHTNSNESDSSPGRSPMQAVHPVHVKEEPLDPEEAEGPLS -------------------------------------------------------------- >62950_62950_40_PAX5-FOXP1_PAX5_chr9_37002645_ENST00000522003_FOXP1_chr3_71064806_ENST00000493089_length(amino acids)=386AA_BP=1 MSHEEHPHSHPLYGHGVCKWPGCEAVCEDFQSFLKHLNSEHALDDRSTAQCRVQMQVVQQLELQLAKDKERLQAMMTHLHVKSTEPKAAP QPLNLVSSVTLSKSASEASPQSLPHTPTTPTAPLTPVTQGPSVITTTSMHTVGPIRRRYSDKYNVPISSDIAQNQEFYKNAEVRPPFTYA SLIRQAILESPEKQLTLNEIYNWFTRMFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVEFQKRRPQKISGNPSLIKNMQS SHAYCTPLNAALQASMAENSIPLYTTASMGNPTLGNLASAIREELNGAMEHTNSNESDSSPGRSPMQAVHPVHVKEEPLDPEEAEGPLSL -------------------------------------------------------------- >62950_62950_41_PAX5-FOXP1_PAX5_chr9_37002645_ENST00000523145_FOXP1_chr3_71064806_ENST00000318789_length(amino acids)=387AA_BP=1 MSHEEHPHSHPLYGHGVCKWPGCEAVCEDFQSFLKHLNSEHALDDRSTAQCRVQMQVVQQLELQLAKDKERLQAMMTHLHVKSTEPKAAP QPLNLVSSVTLSKSASEASPQSLPHTPTTPTAPLTPVTQGPSVITTTSMHTVGPIRRRYSDKYNVPISSADIAQNQEFYKNAEVRPPFTY ASLIRQAILESPEKQLTLNEIYNWFTRMFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVEFQKRRPQKISGNPSLIKNMQ SSHAYCTPLNAALQASMAENSIPLYTTASMGNPTLGNLASAIREELNGAMEHTNSNESDSSPGRSPMQAVHPVHVKEEPLDPEEAEGPLS -------------------------------------------------------------- >62950_62950_42_PAX5-FOXP1_PAX5_chr9_37002645_ENST00000523145_FOXP1_chr3_71064806_ENST00000475937_length(amino acids)=387AA_BP=1 MSHEEHPHSHPLYGHGVCKWPGCEAVCEDFQSFLKHLNSEHALDDRSTAQCRVQMQVVQQLELQLAKDKERLQAMMTHLHVKSTEPKAAP QPLNLVSSVTLSKSASEASPQSLPHTPTTPTAPLTPVTQGPSVITTTSMHTVGPIRRRYSDKYNVPISSADIAQNQEFYKNAEVRPPFTY ASLIRQAILESPEKQLTLNEIYNWFTRMFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVEFQKRRPQKISGNPSLIKNMQ SSHAYCTPLNAALQASMAENSIPLYTTASMGNPTLGNLASAIREELNGAMEHTNSNESDSSPGRSPMQAVHPVHVKEEPLDPEEAEGPLS -------------------------------------------------------------- >62950_62950_43_PAX5-FOXP1_PAX5_chr9_37002645_ENST00000523145_FOXP1_chr3_71064806_ENST00000484350_length(amino acids)=387AA_BP=1 MSHEEHPHSHPLYGHGVCKWPGCEAVCEDFQSFLKHLNSEHALDDRSTAQCRVQMQVVQQLELQLAKDKERLQAMMTHLHVKSTEPKAAP QPLNLVSSVTLSKSASEASPQSLPHTPTTPTAPLTPVTQGPSVITTTSMHTVGPIRRRYSDKYNVPISSADIAQNQEFYKNAEVRPPFTY ASLIRQAILESPEKQLTLNEIYNWFTRMFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVEFQKRRPQKISGNPSLIKNMQ SSHAYCTPLNAALQASMAENSIPLYTTASMGNPTLGNLASAIREELNGAMEHTNSNESDSSPGRSPMQAVHPVHVKEEPLDPEEAEGPLS -------------------------------------------------------------- >62950_62950_44_PAX5-FOXP1_PAX5_chr9_37002645_ENST00000523145_FOXP1_chr3_71064806_ENST00000493089_length(amino acids)=386AA_BP=1 MSHEEHPHSHPLYGHGVCKWPGCEAVCEDFQSFLKHLNSEHALDDRSTAQCRVQMQVVQQLELQLAKDKERLQAMMTHLHVKSTEPKAAP QPLNLVSSVTLSKSASEASPQSLPHTPTTPTAPLTPVTQGPSVITTTSMHTVGPIRRRYSDKYNVPISSDIAQNQEFYKNAEVRPPFTYA SLIRQAILESPEKQLTLNEIYNWFTRMFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVEFQKRRPQKISGNPSLIKNMQS SHAYCTPLNAALQASMAENSIPLYTTASMGNPTLGNLASAIREELNGAMEHTNSNESDSSPGRSPMQAVHPVHVKEEPLDPEEAEGPLSL -------------------------------------------------------------- |
Top |
Fusion Protein Functional Features |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr9:37034075/chr3:71008061) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| PAX5 | FOXP1 |
| FUNCTION: Transcription factor that plays an essential role in commitment of lymphoid progenitors to the B-lymphocyte lineage (PubMed:10811620, PubMed:27181361). Fulfills a dual role by repressing B-lineage inappropriate genes and simultaneously activating B-lineage-specific genes (PubMed:10811620, PubMed:27181361). In turn, regulates cell adhesion and migration, induces V(H)-to-D(H)J(H) recombination, facilitates pre-B-cell receptor signaling and promotes development to the mature B-cell stage (PubMed:32612238). Repression of the cohesin-release factor WAPL causes global changes of the chromosomal architecture in pro-B cells to facilitate the generation of a diverse antibody repertoire (PubMed:32612238). {ECO:0000269|PubMed:10811620, ECO:0000269|PubMed:27181361, ECO:0000269|PubMed:32612238}.; FUNCTION: (Microbial infection) Plays an essential role in the maintenance of Epstein-Barr virus genome copy number within the host cell by promoting EBNA1/oriP-dependent binding and transcription (PubMed:31941781). Participates also in the inhibition of lytic EBV reactivation by modulating viral BZLF1 activity (PubMed:23678172). {ECO:0000269|PubMed:23678172, ECO:0000269|PubMed:31941781}. | FUNCTION: Transcriptional repressor (PubMed:18347093, PubMed:26647308). Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential (By similarity). Plays an important role in the specification and differentiation of lung epithelium. Acts cooperatively with FOXP4 to regulate lung secretory epithelial cell fate and regeneration by restricting the goblet cell lineage program; the function may involve regulation of AGR2. Essential transcriptional regulator of B-cell development. Involved in regulation of cardiac muscle cell proliferation. Involved in the columnar organization of spinal motor neurons. Promotes the formation of the lateral motor neuron column (LMC) and the preganglionic motor column (PGC) and is required for respective appropriate motor axon projections. The segment-appropriate generation of spinal chord motor columns requires cooperation with other Hox proteins. Can regulate PITX3 promoter activity; may promote midbrain identity in embryonic stem cell-derived dopamine neurons by regulating PITX3. Negatively regulates the differentiation of T follicular helper cells T(FH)s. Involved in maintenance of hair follicle stem cell quiescence; the function probably involves regulation of FGF18 (By similarity). Represses transcription of various pro-apoptotic genes and cooperates with NF-kappa B-signaling in promoting B-cell expansion by inhibition of caspase-dependent apoptosis (PubMed:25267198). Binds to CSF1R promoter elements and is involved in regulation of monocyte differentiation and macrophage functions; repression of CSF1R in monocytes seems to involve NCOR2 as corepressor (PubMed:15286807, PubMed:18799727, PubMed:18347093). Involved in endothelial cell proliferation, tube formation and migration indicative for a role in angiogenesis; the role in neovascularization seems to implicate suppression of SEMA5B (PubMed:24023716). Can negatively regulate androgen receptor signaling (PubMed:18640093). Acts as a transcriptional activator of the FBXL7 promoter; this activity is regulated by AURKA (PubMed:28218735). {ECO:0000250|UniProtKB:P58462, ECO:0000269|PubMed:15286807, ECO:0000269|PubMed:18640093, ECO:0000269|PubMed:18799727, ECO:0000269|PubMed:24023716, ECO:0000269|PubMed:25267198, ECO:0000269|PubMed:26647308, ECO:0000269|PubMed:28218735, ECO:0000305|PubMed:18347093, ECO:0000305|PubMed:24023716}.; FUNCTION: [Isoform 8]: Involved in transcriptional regulation in embryonic stem cells (ESCs). Stimulates expression of transcription factors that are required for pluripotency and decreases expression of differentiation-associated genes. Has distinct DNA-binding specifities as compared to the canonical form and preferentially binds DNA with the sequence 5'-CGATACAA-3' (or closely related sequences) (PubMed:21924763). Promotes ESC self-renewal and pluripotency (By similarity). {ECO:0000250|UniProtKB:P58462, ECO:0000269|PubMed:21924763}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - Retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | PAX5 | chr9:36966545 | chr3:71161791 | ENST00000358127 | - | 6 | 10 | 16_142 | 260.0 | 392.0 | DNA binding | Paired |
| Hgene | PAX5 | chr9:36966545 | chr3:71161791 | ENST00000377847 | - | 6 | 8 | 16_142 | 260.0 | 329.0 | DNA binding | Paired |
| Hgene | PAX5 | chr9:36966545 | chr3:71161791 | ENST00000377852 | - | 6 | 9 | 16_142 | 260.0 | 358.0 | DNA binding | Paired |
| Hgene | PAX5 | chr9:36966545 | chr3:71161791 | ENST00000377853 | - | 6 | 9 | 16_142 | 260.0 | 363.0 | DNA binding | Paired |
| Hgene | PAX5 | chr9:36966545 | chr3:71161791 | ENST00000414447 | - | 5 | 9 | 16_142 | 217.0 | 349.0 | DNA binding | Paired |
| Hgene | PAX5 | chr9:36966545 | chr3:71161791 | ENST00000446742 | - | 5 | 8 | 16_142 | 194.0 | 292.0 | DNA binding | Paired |
| Hgene | PAX5 | chr9:36966545 | chr3:71161791 | ENST00000520281 | - | 5 | 8 | 16_142 | 217.0 | 320.0 | DNA binding | Paired |
| Hgene | PAX5 | chr9:37002645 | chr3:71064806 | ENST00000358127 | - | 5 | 10 | 16_142 | 201.33333333333334 | 392.0 | DNA binding | Paired |
| Hgene | PAX5 | chr9:37002645 | chr3:71064806 | ENST00000377847 | - | 5 | 8 | 16_142 | 201.33333333333334 | 329.0 | DNA binding | Paired |
| Hgene | PAX5 | chr9:37002645 | chr3:71064806 | ENST00000377852 | - | 5 | 9 | 16_142 | 201.33333333333334 | 358.0 | DNA binding | Paired |
| Hgene | PAX5 | chr9:37002645 | chr3:71064806 | ENST00000377853 | - | 5 | 9 | 16_142 | 201.33333333333334 | 363.0 | DNA binding | Paired |
| Hgene | PAX5 | chr9:36966545 | chr3:71161791 | ENST00000358127 | - | 6 | 10 | 19_75 | 260.0 | 392.0 | Region | PAI subdomain |
| Hgene | PAX5 | chr9:36966545 | chr3:71161791 | ENST00000358127 | - | 6 | 10 | 94_142 | 260.0 | 392.0 | Region | RED subdomain |
| Hgene | PAX5 | chr9:36966545 | chr3:71161791 | ENST00000377847 | - | 6 | 8 | 19_75 | 260.0 | 329.0 | Region | PAI subdomain |
| Hgene | PAX5 | chr9:36966545 | chr3:71161791 | ENST00000377847 | - | 6 | 8 | 94_142 | 260.0 | 329.0 | Region | RED subdomain |
| Hgene | PAX5 | chr9:36966545 | chr3:71161791 | ENST00000377852 | - | 6 | 9 | 19_75 | 260.0 | 358.0 | Region | PAI subdomain |
| Hgene | PAX5 | chr9:36966545 | chr3:71161791 | ENST00000377852 | - | 6 | 9 | 94_142 | 260.0 | 358.0 | Region | RED subdomain |
| Hgene | PAX5 | chr9:36966545 | chr3:71161791 | ENST00000377853 | - | 6 | 9 | 19_75 | 260.0 | 363.0 | Region | PAI subdomain |
| Hgene | PAX5 | chr9:36966545 | chr3:71161791 | ENST00000377853 | - | 6 | 9 | 94_142 | 260.0 | 363.0 | Region | RED subdomain |
| Hgene | PAX5 | chr9:36966545 | chr3:71161791 | ENST00000414447 | - | 5 | 9 | 19_75 | 217.0 | 349.0 | Region | PAI subdomain |
| Hgene | PAX5 | chr9:36966545 | chr3:71161791 | ENST00000414447 | - | 5 | 9 | 94_142 | 217.0 | 349.0 | Region | RED subdomain |
| Hgene | PAX5 | chr9:36966545 | chr3:71161791 | ENST00000446742 | - | 5 | 8 | 19_75 | 194.0 | 292.0 | Region | PAI subdomain |
| Hgene | PAX5 | chr9:36966545 | chr3:71161791 | ENST00000446742 | - | 5 | 8 | 94_142 | 194.0 | 292.0 | Region | RED subdomain |
| Hgene | PAX5 | chr9:36966545 | chr3:71161791 | ENST00000520281 | - | 5 | 8 | 19_75 | 217.0 | 320.0 | Region | PAI subdomain |
| Hgene | PAX5 | chr9:36966545 | chr3:71161791 | ENST00000520281 | - | 5 | 8 | 94_142 | 217.0 | 320.0 | Region | RED subdomain |
| Hgene | PAX5 | chr9:37002645 | chr3:71064806 | ENST00000358127 | - | 5 | 10 | 19_75 | 201.33333333333334 | 392.0 | Region | PAI subdomain |
| Hgene | PAX5 | chr9:37002645 | chr3:71064806 | ENST00000358127 | - | 5 | 10 | 94_142 | 201.33333333333334 | 392.0 | Region | RED subdomain |
| Hgene | PAX5 | chr9:37002645 | chr3:71064806 | ENST00000377847 | - | 5 | 8 | 19_75 | 201.33333333333334 | 329.0 | Region | PAI subdomain |
| Hgene | PAX5 | chr9:37002645 | chr3:71064806 | ENST00000377847 | - | 5 | 8 | 94_142 | 201.33333333333334 | 329.0 | Region | RED subdomain |
| Hgene | PAX5 | chr9:37002645 | chr3:71064806 | ENST00000377852 | - | 5 | 9 | 19_75 | 201.33333333333334 | 358.0 | Region | PAI subdomain |
| Hgene | PAX5 | chr9:37002645 | chr3:71064806 | ENST00000377852 | - | 5 | 9 | 94_142 | 201.33333333333334 | 358.0 | Region | RED subdomain |
| Hgene | PAX5 | chr9:37002645 | chr3:71064806 | ENST00000377853 | - | 5 | 9 | 19_75 | 201.33333333333334 | 363.0 | Region | PAI subdomain |
| Hgene | PAX5 | chr9:37002645 | chr3:71064806 | ENST00000377853 | - | 5 | 9 | 94_142 | 201.33333333333334 | 363.0 | Region | RED subdomain |
| Hgene | PAX5 | chr9:37002645 | chr3:71064806 | ENST00000446742 | - | 4 | 8 | 19_75 | 135.33333333333334 | 292.0 | Region | PAI subdomain |
| Tgene | FOXP1 | chr9:36966545 | chr3:71161791 | ENST00000318779 | 0 | 7 | 55_230 | 0 | 115.0 | Compositional bias | Note=Gln-rich | |
| Tgene | FOXP1 | chr9:37002645 | chr3:71064806 | ENST00000318779 | 0 | 7 | 55_230 | 0 | 115.0 | Compositional bias | Note=Gln-rich | |
| Tgene | FOXP1 | chr9:36966545 | chr3:71161791 | ENST00000318779 | 0 | 7 | 465_555 | 0 | 115.0 | DNA binding | Fork-head | |
| Tgene | FOXP1 | chr9:36966545 | chr3:71161791 | ENST00000318789 | 5 | 21 | 465_555 | 60.0 | 678.0 | DNA binding | Fork-head | |
| Tgene | FOXP1 | chr9:36966545 | chr3:71161791 | ENST00000475937 | 4 | 20 | 465_555 | 60.0 | 678.0 | DNA binding | Fork-head | |
| Tgene | FOXP1 | chr9:36966545 | chr3:71161791 | ENST00000484350 | 2 | 16 | 465_555 | 60.0 | 602.0 | DNA binding | Fork-head | |
| Tgene | FOXP1 | chr9:36966545 | chr3:71161791 | ENST00000493089 | 5 | 21 | 465_555 | 60.0 | 677.0 | DNA binding | Fork-head | |
| Tgene | FOXP1 | chr9:36966545 | chr3:71161791 | ENST00000498215 | 1 | 17 | 465_555 | 60.0 | 678.0 | DNA binding | Fork-head | |
| Tgene | FOXP1 | chr9:37002645 | chr3:71064806 | ENST00000318779 | 0 | 7 | 465_555 | 0 | 115.0 | DNA binding | Fork-head | |
| Tgene | FOXP1 | chr9:37002645 | chr3:71064806 | ENST00000318789 | 10 | 21 | 465_555 | 289.6666666666667 | 678.0 | DNA binding | Fork-head | |
| Tgene | FOXP1 | chr9:37002645 | chr3:71064806 | ENST00000475937 | 9 | 20 | 465_555 | 289.6666666666667 | 678.0 | DNA binding | Fork-head | |
| Tgene | FOXP1 | chr9:37002645 | chr3:71064806 | ENST00000484350 | 5 | 16 | 465_555 | 213.66666666666666 | 602.0 | DNA binding | Fork-head | |
| Tgene | FOXP1 | chr9:37002645 | chr3:71064806 | ENST00000493089 | 10 | 21 | 465_555 | 289.6666666666667 | 677.0 | DNA binding | Fork-head | |
| Tgene | FOXP1 | chr9:37002645 | chr3:71064806 | ENST00000498215 | 6 | 17 | 465_555 | 289.6666666666667 | 678.0 | DNA binding | Fork-head | |
| Tgene | FOXP1 | chr9:36966545 | chr3:71161791 | ENST00000318779 | 0 | 7 | 348_369 | 0 | 115.0 | Region | Note=Leucine-zipper | |
| Tgene | FOXP1 | chr9:36966545 | chr3:71161791 | ENST00000318779 | 0 | 7 | 382_386 | 0 | 115.0 | Region | CTBP1-binding | |
| Tgene | FOXP1 | chr9:36966545 | chr3:71161791 | ENST00000318789 | 5 | 21 | 348_369 | 60.0 | 678.0 | Region | Note=Leucine-zipper | |
| Tgene | FOXP1 | chr9:36966545 | chr3:71161791 | ENST00000318789 | 5 | 21 | 382_386 | 60.0 | 678.0 | Region | CTBP1-binding | |
| Tgene | FOXP1 | chr9:36966545 | chr3:71161791 | ENST00000475937 | 4 | 20 | 348_369 | 60.0 | 678.0 | Region | Note=Leucine-zipper | |
| Tgene | FOXP1 | chr9:36966545 | chr3:71161791 | ENST00000475937 | 4 | 20 | 382_386 | 60.0 | 678.0 | Region | CTBP1-binding | |
| Tgene | FOXP1 | chr9:36966545 | chr3:71161791 | ENST00000484350 | 2 | 16 | 348_369 | 60.0 | 602.0 | Region | Note=Leucine-zipper | |
| Tgene | FOXP1 | chr9:36966545 | chr3:71161791 | ENST00000484350 | 2 | 16 | 382_386 | 60.0 | 602.0 | Region | CTBP1-binding | |
| Tgene | FOXP1 | chr9:36966545 | chr3:71161791 | ENST00000493089 | 5 | 21 | 348_369 | 60.0 | 677.0 | Region | Note=Leucine-zipper | |
| Tgene | FOXP1 | chr9:36966545 | chr3:71161791 | ENST00000493089 | 5 | 21 | 382_386 | 60.0 | 677.0 | Region | CTBP1-binding | |
| Tgene | FOXP1 | chr9:36966545 | chr3:71161791 | ENST00000498215 | 1 | 17 | 348_369 | 60.0 | 678.0 | Region | Note=Leucine-zipper | |
| Tgene | FOXP1 | chr9:36966545 | chr3:71161791 | ENST00000498215 | 1 | 17 | 382_386 | 60.0 | 678.0 | Region | CTBP1-binding | |
| Tgene | FOXP1 | chr9:37002645 | chr3:71064806 | ENST00000318779 | 0 | 7 | 348_369 | 0 | 115.0 | Region | Note=Leucine-zipper | |
| Tgene | FOXP1 | chr9:37002645 | chr3:71064806 | ENST00000318779 | 0 | 7 | 382_386 | 0 | 115.0 | Region | CTBP1-binding | |
| Tgene | FOXP1 | chr9:37002645 | chr3:71064806 | ENST00000318789 | 10 | 21 | 348_369 | 289.6666666666667 | 678.0 | Region | Note=Leucine-zipper | |
| Tgene | FOXP1 | chr9:37002645 | chr3:71064806 | ENST00000318789 | 10 | 21 | 382_386 | 289.6666666666667 | 678.0 | Region | CTBP1-binding | |
| Tgene | FOXP1 | chr9:37002645 | chr3:71064806 | ENST00000475937 | 9 | 20 | 348_369 | 289.6666666666667 | 678.0 | Region | Note=Leucine-zipper | |
| Tgene | FOXP1 | chr9:37002645 | chr3:71064806 | ENST00000475937 | 9 | 20 | 382_386 | 289.6666666666667 | 678.0 | Region | CTBP1-binding | |
| Tgene | FOXP1 | chr9:37002645 | chr3:71064806 | ENST00000484350 | 5 | 16 | 348_369 | 213.66666666666666 | 602.0 | Region | Note=Leucine-zipper | |
| Tgene | FOXP1 | chr9:37002645 | chr3:71064806 | ENST00000484350 | 5 | 16 | 382_386 | 213.66666666666666 | 602.0 | Region | CTBP1-binding | |
| Tgene | FOXP1 | chr9:37002645 | chr3:71064806 | ENST00000493089 | 10 | 21 | 348_369 | 289.6666666666667 | 677.0 | Region | Note=Leucine-zipper | |
| Tgene | FOXP1 | chr9:37002645 | chr3:71064806 | ENST00000493089 | 10 | 21 | 382_386 | 289.6666666666667 | 677.0 | Region | CTBP1-binding | |
| Tgene | FOXP1 | chr9:37002645 | chr3:71064806 | ENST00000498215 | 6 | 17 | 348_369 | 289.6666666666667 | 678.0 | Region | Note=Leucine-zipper | |
| Tgene | FOXP1 | chr9:37002645 | chr3:71064806 | ENST00000498215 | 6 | 17 | 382_386 | 289.6666666666667 | 678.0 | Region | CTBP1-binding | |
| Tgene | FOXP1 | chr9:36966545 | chr3:71161791 | ENST00000318779 | 0 | 7 | 306_331 | 0 | 115.0 | Zinc finger | Note=C2H2-type | |
| Tgene | FOXP1 | chr9:36966545 | chr3:71161791 | ENST00000318789 | 5 | 21 | 306_331 | 60.0 | 678.0 | Zinc finger | Note=C2H2-type | |
| Tgene | FOXP1 | chr9:36966545 | chr3:71161791 | ENST00000475937 | 4 | 20 | 306_331 | 60.0 | 678.0 | Zinc finger | Note=C2H2-type | |
| Tgene | FOXP1 | chr9:36966545 | chr3:71161791 | ENST00000484350 | 2 | 16 | 306_331 | 60.0 | 602.0 | Zinc finger | Note=C2H2-type | |
| Tgene | FOXP1 | chr9:36966545 | chr3:71161791 | ENST00000493089 | 5 | 21 | 306_331 | 60.0 | 677.0 | Zinc finger | Note=C2H2-type | |
| Tgene | FOXP1 | chr9:36966545 | chr3:71161791 | ENST00000498215 | 1 | 17 | 306_331 | 60.0 | 678.0 | Zinc finger | Note=C2H2-type | |
| Tgene | FOXP1 | chr9:37002645 | chr3:71064806 | ENST00000318779 | 0 | 7 | 306_331 | 0 | 115.0 | Zinc finger | Note=C2H2-type | |
| Tgene | FOXP1 | chr9:37002645 | chr3:71064806 | ENST00000318789 | 10 | 21 | 306_331 | 289.6666666666667 | 678.0 | Zinc finger | Note=C2H2-type | |
| Tgene | FOXP1 | chr9:37002645 | chr3:71064806 | ENST00000475937 | 9 | 20 | 306_331 | 289.6666666666667 | 678.0 | Zinc finger | Note=C2H2-type | |
| Tgene | FOXP1 | chr9:37002645 | chr3:71064806 | ENST00000484350 | 5 | 16 | 306_331 | 213.66666666666666 | 602.0 | Zinc finger | Note=C2H2-type | |
| Tgene | FOXP1 | chr9:37002645 | chr3:71064806 | ENST00000493089 | 10 | 21 | 306_331 | 289.6666666666667 | 677.0 | Zinc finger | Note=C2H2-type | |
| Tgene | FOXP1 | chr9:37002645 | chr3:71064806 | ENST00000498215 | 6 | 17 | 306_331 | 289.6666666666667 | 678.0 | Zinc finger | Note=C2H2-type |
| - Not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | PAX5 | chr9:37002645 | chr3:71064806 | ENST00000414447 | - | 1 | 9 | 16_142 | 0.0 | 349.0 | DNA binding | Paired |
| Hgene | PAX5 | chr9:37002645 | chr3:71064806 | ENST00000446742 | - | 4 | 8 | 16_142 | 135.33333333333334 | 292.0 | DNA binding | Paired |
| Hgene | PAX5 | chr9:37002645 | chr3:71064806 | ENST00000520281 | - | 1 | 8 | 16_142 | 0.0 | 320.0 | DNA binding | Paired |
| Hgene | PAX5 | chr9:37002645 | chr3:71064806 | ENST00000414447 | - | 1 | 9 | 19_75 | 0.0 | 349.0 | Region | PAI subdomain |
| Hgene | PAX5 | chr9:37002645 | chr3:71064806 | ENST00000414447 | - | 1 | 9 | 94_142 | 0.0 | 349.0 | Region | RED subdomain |
| Hgene | PAX5 | chr9:37002645 | chr3:71064806 | ENST00000446742 | - | 4 | 8 | 94_142 | 135.33333333333334 | 292.0 | Region | RED subdomain |
| Hgene | PAX5 | chr9:37002645 | chr3:71064806 | ENST00000520281 | - | 1 | 8 | 19_75 | 0.0 | 320.0 | Region | PAI subdomain |
| Hgene | PAX5 | chr9:37002645 | chr3:71064806 | ENST00000520281 | - | 1 | 8 | 94_142 | 0.0 | 320.0 | Region | RED subdomain |
| Tgene | FOXP1 | chr9:36966545 | chr3:71161791 | ENST00000318789 | 5 | 21 | 55_230 | 60.0 | 678.0 | Compositional bias | Note=Gln-rich | |
| Tgene | FOXP1 | chr9:36966545 | chr3:71161791 | ENST00000475937 | 4 | 20 | 55_230 | 60.0 | 678.0 | Compositional bias | Note=Gln-rich | |
| Tgene | FOXP1 | chr9:36966545 | chr3:71161791 | ENST00000484350 | 2 | 16 | 55_230 | 60.0 | 602.0 | Compositional bias | Note=Gln-rich | |
| Tgene | FOXP1 | chr9:36966545 | chr3:71161791 | ENST00000493089 | 5 | 21 | 55_230 | 60.0 | 677.0 | Compositional bias | Note=Gln-rich | |
| Tgene | FOXP1 | chr9:36966545 | chr3:71161791 | ENST00000498215 | 1 | 17 | 55_230 | 60.0 | 678.0 | Compositional bias | Note=Gln-rich | |
| Tgene | FOXP1 | chr9:37002645 | chr3:71064806 | ENST00000318789 | 10 | 21 | 55_230 | 289.6666666666667 | 678.0 | Compositional bias | Note=Gln-rich | |
| Tgene | FOXP1 | chr9:37002645 | chr3:71064806 | ENST00000475937 | 9 | 20 | 55_230 | 289.6666666666667 | 678.0 | Compositional bias | Note=Gln-rich | |
| Tgene | FOXP1 | chr9:37002645 | chr3:71064806 | ENST00000484350 | 5 | 16 | 55_230 | 213.66666666666666 | 602.0 | Compositional bias | Note=Gln-rich | |
| Tgene | FOXP1 | chr9:37002645 | chr3:71064806 | ENST00000493089 | 10 | 21 | 55_230 | 289.6666666666667 | 677.0 | Compositional bias | Note=Gln-rich | |
| Tgene | FOXP1 | chr9:37002645 | chr3:71064806 | ENST00000498215 | 6 | 17 | 55_230 | 289.6666666666667 | 678.0 | Compositional bias | Note=Gln-rich |
Top |
Fusion Protein-Protein Interaction |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type from validated records (BIOGRID-3.4.160) |
| Gene | PPI interactors |
| PAX5 | TLE4, DAXX, RUNX1, MYB, ID3, EP300, TBP, RB1, MAPK1, KAT2B, CDKN1B, UBE3A, RAD52, HMGB3, HOXC8, MAPK9, NFYC, FBLN1, GRHL2, DTX2, CSNK2A1, UBE2I, CCNC, BCAS2, C1orf109, GNG13, ZMYM5, SEC14L4, RNF144B, OSGIN1, CIB3, SAE1, STAC, TLK2, HMBOX1, NGLY1, NEIL2, LONRF1, LDLRAP1, LARP4, UBXN7, ACOT12, CKS1B, KLHL38, HGS, CXorf38, KRTAP10-8, PNMA5, KRTAP9-3, UBXN2B, CDK3, BKRF1, HIST1H3A, PAX8, KLHL14, |
| Protein-protein interactors based on sequence similarity (STRING) |
| Gene | STRING network |
| PAX5 |  |
| FOXP1 |
| - Retained interactions in fusion protein (protein functional feature from UniProt). |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost interactions due to fusion (protein functional feature from UniProt). |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
Top |
Related Drugs to PAX5-FOXP1 |
| Drugs used for this fusion-positive patient. (Manual curation of PubMed, 04-30-2022 + MyCancerGenome) |
| Hgene | Tgene | Drug | Source | PMID |
Top |
Related Diseases to PAX5-FOXP1 |
| Diseases that have this fusion gene. (Manual curation of PubMed, 04-30-2022 + MyCancerGenome) |
| Hgene | Tgene | Disease | Source | PMID |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | PAX5 | C0006413 | Burkitt Lymphoma | 4 | ORPHANET |
| Hgene | PAX5 | C1292769 | Precursor B-cell lymphoblastic leukemia | 4 | ORPHANET |
| Hgene | PAX5 | C0023485 | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma | 2 | CTD_human |
| Hgene | PAX5 | C1961102 | Precursor Cell Lymphoblastic Leukemia Lymphoma | 2 | CGI;CTD_human;UNIPROT |
| Hgene | PAX5 | C0023452 | Childhood Acute Lymphoblastic Leukemia | 1 | CTD_human |
| Hgene | PAX5 | C0023453 | L2 Acute Lymphoblastic Leukemia | 1 | CTD_human |
| Hgene | PAX5 | C1535926 | Neurodevelopmental Disorders | 1 | CTD_human |
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