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Fusion Protein:ARID1B-PLEKHG1 |
Fusion Protein Summary |
 Fusion gene summary |
| Fusion partner gene information | Fusion gene name: ARID1B-PLEKHG1 | FusionPDB ID: 6413 | FusionGDB2.0 ID: 6413 | Hgene | Tgene | Gene symbol | ARID1B | PLEKHG1 | Gene ID | 57492 | 57480 |
| Gene name | AT-rich interaction domain 1B | pleckstrin homology and RhoGEF domain containing G1 | |
| Synonyms | 6A3-5|BAF250B|BRIGHT|CSS1|DAN15|ELD/OSA1|MRD12|OSA2|P250R | ARHGEF41 | |
| Cytomap | 6q25.3 | 6q25.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | AT-rich interactive domain-containing protein 1BARID domain-containing protein 1BAT rich interactive domain 1B (SWI1-like)BRG1-associated factor 250bBRG1-binding protein ELD/OSA1ELD (eyelid)/OSA protein | pleckstrin homology domain-containing family G member 1pleckstrin homology domain containing, family G (with RhoGef domain) member 1 | |
| Modification date | 20200320 | 20200313 | |
| UniProtAcc | Q8NFD5 | . | |
| Ensembl transtripts involved in fusion gene | ENST ids | ENST00000275248, ENST00000346085, ENST00000350026, ENST00000367148, ENST00000478761, | ENST00000358517, ENST00000367328, |
| Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0) | * DoF score | 27 X 18 X 14=6804 | 11 X 13 X 5=715 |
| # samples | 31 | 12 | |
| ** MAII score | log2(31/6804*10)=-4.45604302038915 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(12/715*10)=-2.57490883605723 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context (manual curation of fusion genes in FusionPDB) | PubMed: ARID1B [Title/Abstract] AND PLEKHG1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0) | ARID1B(157256710)-PLEKHG1(151089774), # samples:3 | ||
| Anticipated loss of major functional domain due to fusion event. | ARID1B-PLEKHG1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. ARID1B-PLEKHG1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. ARID1B-PLEKHG1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. ARID1B-PLEKHG1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene breakpoints across ARID1B (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across PLEKHG1 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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Fusion Gene Sample Information |
| Fusion gene information from FusionGDB2.0. |
| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | BRCA | TCGA-E9-A248-01A | ARID1B | chr6 | 157256709 | + | PLEKHG1 | chr6 | 151089773 | + |
| ChimerDB4 | BRCA | TCGA-E9-A248-01A | ARID1B | chr6 | 157256710 | - | PLEKHG1 | chr6 | 151089774 | + |
| ChimerDB4 | BRCA | TCGA-E9-A248-01A | ARID1B | chr6 | 157256710 | + | PLEKHG1 | chr6 | 151089774 | + |
| ChimerDB4 | BRCA | TCGA-E9-A248 | ARID1B | chr6 | 157256710 | + | PLEKHG1 | chr6 | 151089773 | + |
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Fusion ORF Analysis |
| Fusion information from ORFfinder translation from full-length transcript sequence from FusionPDB. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000350026 | ARID1B | chr6 | 157256710 | + | ENST00000367328 | PLEKHG1 | chr6 | 151089774 | + | 8513 | 1999 | 1 | 5745 | 1914 |
| ENST00000350026 | ARID1B | chr6 | 157256710 | + | ENST00000358517 | PLEKHG1 | chr6 | 151089774 | + | 8513 | 1999 | 1 | 5745 | 1914 |
| ENST00000346085 | ARID1B | chr6 | 157256710 | + | ENST00000367328 | PLEKHG1 | chr6 | 151089774 | + | 8552 | 2038 | 1 | 5784 | 1927 |
| ENST00000346085 | ARID1B | chr6 | 157256710 | + | ENST00000358517 | PLEKHG1 | chr6 | 151089774 | + | 8552 | 2038 | 1 | 5784 | 1927 |
| ENST00000367148 | ARID1B | chr6 | 157256710 | + | ENST00000367328 | PLEKHG1 | chr6 | 151089774 | + | 8512 | 1998 | 0 | 5744 | 1914 |
| ENST00000367148 | ARID1B | chr6 | 157256710 | + | ENST00000358517 | PLEKHG1 | chr6 | 151089774 | + | 8512 | 1998 | 0 | 5744 | 1914 |
| ENST00000275248 | ARID1B | chr6 | 157256710 | + | ENST00000367328 | PLEKHG1 | chr6 | 151089774 | + | 8490 | 1976 | 77 | 5722 | 1881 |
| ENST00000275248 | ARID1B | chr6 | 157256710 | + | ENST00000358517 | PLEKHG1 | chr6 | 151089774 | + | 8490 | 1976 | 77 | 5722 | 1881 |
| ENST00000350026 | ARID1B | chr6 | 157256710 | + | ENST00000367328 | PLEKHG1 | chr6 | 151089773 | + | 8513 | 1999 | 1 | 5745 | 1914 |
| ENST00000350026 | ARID1B | chr6 | 157256710 | + | ENST00000358517 | PLEKHG1 | chr6 | 151089773 | + | 8513 | 1999 | 1 | 5745 | 1914 |
| ENST00000346085 | ARID1B | chr6 | 157256710 | + | ENST00000367328 | PLEKHG1 | chr6 | 151089773 | + | 8552 | 2038 | 1 | 5784 | 1927 |
| ENST00000346085 | ARID1B | chr6 | 157256710 | + | ENST00000358517 | PLEKHG1 | chr6 | 151089773 | + | 8552 | 2038 | 1 | 5784 | 1927 |
| ENST00000367148 | ARID1B | chr6 | 157256710 | + | ENST00000367328 | PLEKHG1 | chr6 | 151089773 | + | 8512 | 1998 | 0 | 5744 | 1914 |
| ENST00000367148 | ARID1B | chr6 | 157256710 | + | ENST00000358517 | PLEKHG1 | chr6 | 151089773 | + | 8512 | 1998 | 0 | 5744 | 1914 |
| ENST00000275248 | ARID1B | chr6 | 157256710 | + | ENST00000367328 | PLEKHG1 | chr6 | 151089773 | + | 8490 | 1976 | 77 | 5722 | 1881 |
| ENST00000275248 | ARID1B | chr6 | 157256710 | + | ENST00000358517 | PLEKHG1 | chr6 | 151089773 | + | 8490 | 1976 | 77 | 5722 | 1881 |
| ENST00000350026 | ARID1B | chr6 | 157256709 | + | ENST00000367328 | PLEKHG1 | chr6 | 151089773 | + | 8513 | 1999 | 1 | 5745 | 1914 |
| ENST00000350026 | ARID1B | chr6 | 157256709 | + | ENST00000358517 | PLEKHG1 | chr6 | 151089773 | + | 8513 | 1999 | 1 | 5745 | 1914 |
| ENST00000346085 | ARID1B | chr6 | 157256709 | + | ENST00000367328 | PLEKHG1 | chr6 | 151089773 | + | 8552 | 2038 | 1 | 5784 | 1927 |
| ENST00000346085 | ARID1B | chr6 | 157256709 | + | ENST00000358517 | PLEKHG1 | chr6 | 151089773 | + | 8552 | 2038 | 1 | 5784 | 1927 |
| ENST00000367148 | ARID1B | chr6 | 157256709 | + | ENST00000367328 | PLEKHG1 | chr6 | 151089773 | + | 8512 | 1998 | 0 | 5744 | 1914 |
| ENST00000367148 | ARID1B | chr6 | 157256709 | + | ENST00000358517 | PLEKHG1 | chr6 | 151089773 | + | 8512 | 1998 | 0 | 5744 | 1914 |
| ENST00000275248 | ARID1B | chr6 | 157256709 | + | ENST00000367328 | PLEKHG1 | chr6 | 151089773 | + | 8490 | 1976 | 77 | 5722 | 1881 |
| ENST00000275248 | ARID1B | chr6 | 157256709 | + | ENST00000358517 | PLEKHG1 | chr6 | 151089773 | + | 8490 | 1976 | 77 | 5722 | 1881 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000350026 | ENST00000367328 | ARID1B | chr6 | 157256710 | + | PLEKHG1 | chr6 | 151089774 | + | 0.000896493 | 0.9991035 |
| ENST00000350026 | ENST00000358517 | ARID1B | chr6 | 157256710 | + | PLEKHG1 | chr6 | 151089774 | + | 0.000896493 | 0.9991035 |
| ENST00000346085 | ENST00000367328 | ARID1B | chr6 | 157256710 | + | PLEKHG1 | chr6 | 151089774 | + | 0.000913495 | 0.9990865 |
| ENST00000346085 | ENST00000358517 | ARID1B | chr6 | 157256710 | + | PLEKHG1 | chr6 | 151089774 | + | 0.000913495 | 0.9990865 |
| ENST00000367148 | ENST00000367328 | ARID1B | chr6 | 157256710 | + | PLEKHG1 | chr6 | 151089774 | + | 0.00089421 | 0.99910575 |
| ENST00000367148 | ENST00000358517 | ARID1B | chr6 | 157256710 | + | PLEKHG1 | chr6 | 151089774 | + | 0.00089421 | 0.99910575 |
| ENST00000275248 | ENST00000367328 | ARID1B | chr6 | 157256710 | + | PLEKHG1 | chr6 | 151089774 | + | 0.001025336 | 0.9989747 |
| ENST00000275248 | ENST00000358517 | ARID1B | chr6 | 157256710 | + | PLEKHG1 | chr6 | 151089774 | + | 0.001025336 | 0.9989747 |
| ENST00000350026 | ENST00000367328 | ARID1B | chr6 | 157256710 | + | PLEKHG1 | chr6 | 151089773 | + | 0.000896493 | 0.9991035 |
| ENST00000350026 | ENST00000358517 | ARID1B | chr6 | 157256710 | + | PLEKHG1 | chr6 | 151089773 | + | 0.000896493 | 0.9991035 |
| ENST00000346085 | ENST00000367328 | ARID1B | chr6 | 157256710 | + | PLEKHG1 | chr6 | 151089773 | + | 0.000913495 | 0.9990865 |
| ENST00000346085 | ENST00000358517 | ARID1B | chr6 | 157256710 | + | PLEKHG1 | chr6 | 151089773 | + | 0.000913495 | 0.9990865 |
| ENST00000367148 | ENST00000367328 | ARID1B | chr6 | 157256710 | + | PLEKHG1 | chr6 | 151089773 | + | 0.00089421 | 0.99910575 |
| ENST00000367148 | ENST00000358517 | ARID1B | chr6 | 157256710 | + | PLEKHG1 | chr6 | 151089773 | + | 0.00089421 | 0.99910575 |
| ENST00000275248 | ENST00000367328 | ARID1B | chr6 | 157256710 | + | PLEKHG1 | chr6 | 151089773 | + | 0.001025336 | 0.9989747 |
| ENST00000275248 | ENST00000358517 | ARID1B | chr6 | 157256710 | + | PLEKHG1 | chr6 | 151089773 | + | 0.001025336 | 0.9989747 |
| ENST00000350026 | ENST00000367328 | ARID1B | chr6 | 157256709 | + | PLEKHG1 | chr6 | 151089773 | + | 0.000896493 | 0.9991035 |
| ENST00000350026 | ENST00000358517 | ARID1B | chr6 | 157256709 | + | PLEKHG1 | chr6 | 151089773 | + | 0.000896493 | 0.9991035 |
| ENST00000346085 | ENST00000367328 | ARID1B | chr6 | 157256709 | + | PLEKHG1 | chr6 | 151089773 | + | 0.000913495 | 0.9990865 |
| ENST00000346085 | ENST00000358517 | ARID1B | chr6 | 157256709 | + | PLEKHG1 | chr6 | 151089773 | + | 0.000913495 | 0.9990865 |
| ENST00000367148 | ENST00000367328 | ARID1B | chr6 | 157256709 | + | PLEKHG1 | chr6 | 151089773 | + | 0.00089421 | 0.99910575 |
| ENST00000367148 | ENST00000358517 | ARID1B | chr6 | 157256709 | + | PLEKHG1 | chr6 | 151089773 | + | 0.00089421 | 0.99910575 |
| ENST00000275248 | ENST00000367328 | ARID1B | chr6 | 157256709 | + | PLEKHG1 | chr6 | 151089773 | + | 0.001025336 | 0.9989747 |
| ENST00000275248 | ENST00000358517 | ARID1B | chr6 | 157256709 | + | PLEKHG1 | chr6 | 151089773 | + | 0.001025336 | 0.9989747 |
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Fusion Amino Acid Sequences |
| For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP >6413_6413_1_ARID1B-PLEKHG1_ARID1B_chr6_157256709_ENST00000275248_PLEKHG1_chr6_151089773_ENST00000358517_length(amino acids)=1881AA_BP=236 MSSSSSSSAAAAAASSSSSSGPGSAMETGLLPNHKLKTVGEAPAAPPHQQHHHHHHAHHHHHHAHHLHHHHALQQQLNQFQQQQQQQQQQ QQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQP PVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSR PGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKA AAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQY AAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGM QYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPS SLPDYLDCIRDQTKLPLGTEERSALFGNIQDIYHFNSELLQDLENCENDPVAIAECFVSKSEEFHIYTQYCTNYPRSVAVLTECMRNKIL AKFFRERQETLKHSLPLGSYLLKPVQRILKYHLLLHEIENHLDKDTEGYDVVLDAIDTMQRVAWHINDMKRKHEHAVRLQEIQSLLTNWK GPDLTSYGELVLEGTFRIQRAKNERTLFLFDKLLLITKKRDDTFTYKAHILCGNLMLVEVIPKEPLSFSVFHYKNPKLQHTVQAKSQQDK RLWVLHLKRLILENHAAKIPAKAKQAILEMDAIHHPGFCYSPEGGTKALFGSKEGSAPYRLRRKSEPSSRSHKVLKTSETAQDIQKVSRE EGSPQLSSARPSPAQRNSQPSSSTMISVLRAGGALRNIWTDHQIRQALFPSRRSPQENEDDEDDYQMFVPSFSSSDLNSTRLCEDSTSSR PCSWHMGQMESTETSSSGHRIVRRASSAGESNTCPPEIGTSDRTRELQNSPKTEGQEEMTPFGSSIELTIDDIDHVYDNISYEDLKLMVA KREEAESTPSKSARDSVRPKSTPELAFTKRQAGHSKGSLYAQTDGTLSGGEASSQSTHELQAVEENIYDTIGLPDPPSLGFKCSSLKRAK RSTFLGLEADFVCCDSLRPFVSQDSLQLSEDEAPYHQATPDHGYLSLLYDSPSGNLSMPHKPVSDKLSEEVDEIWNDLENYIKKNEDKAR DRLLAAFPVSKDDVPDRLHAESTPELSRDVGRSVSTLSLPESQALLTPVKSRAGRASRANCPFEEDLISKEGSFMSLNRLSLASEMPLMD NPYDLANSGLSQTDPENPDLGMEATDKTKSRVFMMARQYSQKIKKANQLLKVKSLELEQPPASQHQKSMHKDLAAILEEKKQGGPAIGAR IAEYSQLYDQIVFRESPLKIQKDGWASPQESSLLRSVSPSQVHHGSGDWLLHSTYSNGELADFCLPPEQDLRSRYPTFEINTKSTPRQLS AACSVPSLQTSDPLPGSVQRCSVVVSQPNKENWCQDHLYNSLGRKGISAKSQPYHRSQSSSSVLINKSMDSINYPSDVGKQQLLSLHRSS RCESHQDLLPDIADSHQQGTEKLSDLTLQDSQKVVVVNRNLPLNAQIATQNYFSNFKETDGDEDDYVEIKSEEDESELELSHNRRRKSDS -------------------------------------------------------------- >6413_6413_2_ARID1B-PLEKHG1_ARID1B_chr6_157256709_ENST00000275248_PLEKHG1_chr6_151089773_ENST00000367328_length(amino acids)=1881AA_BP=236 MSSSSSSSAAAAAASSSSSSGPGSAMETGLLPNHKLKTVGEAPAAPPHQQHHHHHHAHHHHHHAHHLHHHHALQQQLNQFQQQQQQQQQQ QQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQP PVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSR PGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKA AAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQY AAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGM QYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPS SLPDYLDCIRDQTKLPLGTEERSALFGNIQDIYHFNSELLQDLENCENDPVAIAECFVSKSEEFHIYTQYCTNYPRSVAVLTECMRNKIL AKFFRERQETLKHSLPLGSYLLKPVQRILKYHLLLHEIENHLDKDTEGYDVVLDAIDTMQRVAWHINDMKRKHEHAVRLQEIQSLLTNWK GPDLTSYGELVLEGTFRIQRAKNERTLFLFDKLLLITKKRDDTFTYKAHILCGNLMLVEVIPKEPLSFSVFHYKNPKLQHTVQAKSQQDK RLWVLHLKRLILENHAAKIPAKAKQAILEMDAIHHPGFCYSPEGGTKALFGSKEGSAPYRLRRKSEPSSRSHKVLKTSETAQDIQKVSRE EGSPQLSSARPSPAQRNSQPSSSTMISVLRAGGALRNIWTDHQIRQALFPSRRSPQENEDDEDDYQMFVPSFSSSDLNSTRLCEDSTSSR PCSWHMGQMESTETSSSGHRIVRRASSAGESNTCPPEIGTSDRTRELQNSPKTEGQEEMTPFGSSIELTIDDIDHVYDNISYEDLKLMVA KREEAESTPSKSARDSVRPKSTPELAFTKRQAGHSKGSLYAQTDGTLSGGEASSQSTHELQAVEENIYDTIGLPDPPSLGFKCSSLKRAK RSTFLGLEADFVCCDSLRPFVSQDSLQLSEDEAPYHQATPDHGYLSLLYDSPSGNLSMPHKPVSDKLSEEVDEIWNDLENYIKKNEDKAR DRLLAAFPVSKDDVPDRLHAESTPELSRDVGRSVSTLSLPESQALLTPVKSRAGRASRANCPFEEDLISKEGSFMSLNRLSLASEMPLMD NPYDLANSGLSQTDPENPDLGMEATDKTKSRVFMMARQYSQKIKKANQLLKVKSLELEQPPASQHQKSMHKDLAAILEEKKQGGPAIGAR IAEYSQLYDQIVFRESPLKIQKDGWASPQESSLLRSVSPSQVHHGSGDWLLHSTYSNGELADFCLPPEQDLRSRYPTFEINTKSTPRQLS AACSVPSLQTSDPLPGSVQRCSVVVSQPNKENWCQDHLYNSLGRKGISAKSQPYHRSQSSSSVLINKSMDSINYPSDVGKQQLLSLHRSS RCESHQDLLPDIADSHQQGTEKLSDLTLQDSQKVVVVNRNLPLNAQIATQNYFSNFKETDGDEDDYVEIKSEEDESELELSHNRRRKSDS -------------------------------------------------------------- >6413_6413_3_ARID1B-PLEKHG1_ARID1B_chr6_157256709_ENST00000346085_PLEKHG1_chr6_151089773_ENST00000358517_length(amino acids)=1927AA_BP=269 MAHNAGAAAAAGTHSAKSGGSEAALKEGGSAAALSSSSSSSAAAAAASSSSSSGPGSAMETGLLPNHKLKTVGEAPAAPPHQQHHHHHHA HHHHHHAHHLHHHHALQQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLS KPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSAS AAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGG SSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPP SQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQ QSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQDSGDATWKETFWLMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYL PSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDYLDCIRDQTKLPLGTEERSALFGNIQDIYHFNSELLQDLE NCENDPVAIAECFVSKSEEFHIYTQYCTNYPRSVAVLTECMRNKILAKFFRERQETLKHSLPLGSYLLKPVQRILKYHLLLHEIENHLDK DTEGYDVVLDAIDTMQRVAWHINDMKRKHEHAVRLQEIQSLLTNWKGPDLTSYGELVLEGTFRIQRAKNERTLFLFDKLLLITKKRDDTF TYKAHILCGNLMLVEVIPKEPLSFSVFHYKNPKLQHTVQAKSQQDKRLWVLHLKRLILENHAAKIPAKAKQAILEMDAIHHPGFCYSPEG GTKALFGSKEGSAPYRLRRKSEPSSRSHKVLKTSETAQDIQKVSREEGSPQLSSARPSPAQRNSQPSSSTMISVLRAGGALRNIWTDHQI RQALFPSRRSPQENEDDEDDYQMFVPSFSSSDLNSTRLCEDSTSSRPCSWHMGQMESTETSSSGHRIVRRASSAGESNTCPPEIGTSDRT RELQNSPKTEGQEEMTPFGSSIELTIDDIDHVYDNISYEDLKLMVAKREEAESTPSKSARDSVRPKSTPELAFTKRQAGHSKGSLYAQTD GTLSGGEASSQSTHELQAVEENIYDTIGLPDPPSLGFKCSSLKRAKRSTFLGLEADFVCCDSLRPFVSQDSLQLSEDEAPYHQATPDHGY LSLLYDSPSGNLSMPHKPVSDKLSEEVDEIWNDLENYIKKNEDKARDRLLAAFPVSKDDVPDRLHAESTPELSRDVGRSVSTLSLPESQA LLTPVKSRAGRASRANCPFEEDLISKEGSFMSLNRLSLASEMPLMDNPYDLANSGLSQTDPENPDLGMEATDKTKSRVFMMARQYSQKIK KANQLLKVKSLELEQPPASQHQKSMHKDLAAILEEKKQGGPAIGARIAEYSQLYDQIVFRESPLKIQKDGWASPQESSLLRSVSPSQVHH GSGDWLLHSTYSNGELADFCLPPEQDLRSRYPTFEINTKSTPRQLSAACSVPSLQTSDPLPGSVQRCSVVVSQPNKENWCQDHLYNSLGR KGISAKSQPYHRSQSSSSVLINKSMDSINYPSDVGKQQLLSLHRSSRCESHQDLLPDIADSHQQGTEKLSDLTLQDSQKVVVVNRNLPLN AQIATQNYFSNFKETDGDEDDYVEIKSEEDESELELSHNRRRKSDSKFVDADFSDNVCSGNTLHSLNSPRTPKKPVNSKLGLSPYLTPYN -------------------------------------------------------------- >6413_6413_4_ARID1B-PLEKHG1_ARID1B_chr6_157256709_ENST00000346085_PLEKHG1_chr6_151089773_ENST00000367328_length(amino acids)=1927AA_BP=269 MAHNAGAAAAAGTHSAKSGGSEAALKEGGSAAALSSSSSSSAAAAAASSSSSSGPGSAMETGLLPNHKLKTVGEAPAAPPHQQHHHHHHA HHHHHHAHHLHHHHALQQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLS KPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSAS AAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGG SSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPP SQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQ QSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQDSGDATWKETFWLMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYL PSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDYLDCIRDQTKLPLGTEERSALFGNIQDIYHFNSELLQDLE NCENDPVAIAECFVSKSEEFHIYTQYCTNYPRSVAVLTECMRNKILAKFFRERQETLKHSLPLGSYLLKPVQRILKYHLLLHEIENHLDK DTEGYDVVLDAIDTMQRVAWHINDMKRKHEHAVRLQEIQSLLTNWKGPDLTSYGELVLEGTFRIQRAKNERTLFLFDKLLLITKKRDDTF TYKAHILCGNLMLVEVIPKEPLSFSVFHYKNPKLQHTVQAKSQQDKRLWVLHLKRLILENHAAKIPAKAKQAILEMDAIHHPGFCYSPEG GTKALFGSKEGSAPYRLRRKSEPSSRSHKVLKTSETAQDIQKVSREEGSPQLSSARPSPAQRNSQPSSSTMISVLRAGGALRNIWTDHQI RQALFPSRRSPQENEDDEDDYQMFVPSFSSSDLNSTRLCEDSTSSRPCSWHMGQMESTETSSSGHRIVRRASSAGESNTCPPEIGTSDRT RELQNSPKTEGQEEMTPFGSSIELTIDDIDHVYDNISYEDLKLMVAKREEAESTPSKSARDSVRPKSTPELAFTKRQAGHSKGSLYAQTD GTLSGGEASSQSTHELQAVEENIYDTIGLPDPPSLGFKCSSLKRAKRSTFLGLEADFVCCDSLRPFVSQDSLQLSEDEAPYHQATPDHGY LSLLYDSPSGNLSMPHKPVSDKLSEEVDEIWNDLENYIKKNEDKARDRLLAAFPVSKDDVPDRLHAESTPELSRDVGRSVSTLSLPESQA LLTPVKSRAGRASRANCPFEEDLISKEGSFMSLNRLSLASEMPLMDNPYDLANSGLSQTDPENPDLGMEATDKTKSRVFMMARQYSQKIK KANQLLKVKSLELEQPPASQHQKSMHKDLAAILEEKKQGGPAIGARIAEYSQLYDQIVFRESPLKIQKDGWASPQESSLLRSVSPSQVHH GSGDWLLHSTYSNGELADFCLPPEQDLRSRYPTFEINTKSTPRQLSAACSVPSLQTSDPLPGSVQRCSVVVSQPNKENWCQDHLYNSLGR KGISAKSQPYHRSQSSSSVLINKSMDSINYPSDVGKQQLLSLHRSSRCESHQDLLPDIADSHQQGTEKLSDLTLQDSQKVVVVNRNLPLN AQIATQNYFSNFKETDGDEDDYVEIKSEEDESELELSHNRRRKSDSKFVDADFSDNVCSGNTLHSLNSPRTPKKPVNSKLGLSPYLTPYN -------------------------------------------------------------- >6413_6413_5_ARID1B-PLEKHG1_ARID1B_chr6_157256709_ENST00000350026_PLEKHG1_chr6_151089773_ENST00000358517_length(amino acids)=1914AA_BP=269 MAHNAGAAAAAGTHSAKSGGSEAALKEGGSAAALSSSSSSSAAAAAASSSSSSGPGSAMETGLLPNHKLKTVGEAPAAPPHQQHHHHHHA HHHHHHAHHLHHHHALQQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLS KPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSAS AAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGG SSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPP SQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQ QSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQD MSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDYLDCIRDQTKLPLGTEERSALFGNIQDIYHFNSELLQDLENCENDPVAIAECF VSKSEEFHIYTQYCTNYPRSVAVLTECMRNKILAKFFRERQETLKHSLPLGSYLLKPVQRILKYHLLLHEIENHLDKDTEGYDVVLDAID TMQRVAWHINDMKRKHEHAVRLQEIQSLLTNWKGPDLTSYGELVLEGTFRIQRAKNERTLFLFDKLLLITKKRDDTFTYKAHILCGNLML VEVIPKEPLSFSVFHYKNPKLQHTVQAKSQQDKRLWVLHLKRLILENHAAKIPAKAKQAILEMDAIHHPGFCYSPEGGTKALFGSKEGSA PYRLRRKSEPSSRSHKVLKTSETAQDIQKVSREEGSPQLSSARPSPAQRNSQPSSSTMISVLRAGGALRNIWTDHQIRQALFPSRRSPQE NEDDEDDYQMFVPSFSSSDLNSTRLCEDSTSSRPCSWHMGQMESTETSSSGHRIVRRASSAGESNTCPPEIGTSDRTRELQNSPKTEGQE EMTPFGSSIELTIDDIDHVYDNISYEDLKLMVAKREEAESTPSKSARDSVRPKSTPELAFTKRQAGHSKGSLYAQTDGTLSGGEASSQST HELQAVEENIYDTIGLPDPPSLGFKCSSLKRAKRSTFLGLEADFVCCDSLRPFVSQDSLQLSEDEAPYHQATPDHGYLSLLYDSPSGNLS MPHKPVSDKLSEEVDEIWNDLENYIKKNEDKARDRLLAAFPVSKDDVPDRLHAESTPELSRDVGRSVSTLSLPESQALLTPVKSRAGRAS RANCPFEEDLISKEGSFMSLNRLSLASEMPLMDNPYDLANSGLSQTDPENPDLGMEATDKTKSRVFMMARQYSQKIKKANQLLKVKSLEL EQPPASQHQKSMHKDLAAILEEKKQGGPAIGARIAEYSQLYDQIVFRESPLKIQKDGWASPQESSLLRSVSPSQVHHGSGDWLLHSTYSN GELADFCLPPEQDLRSRYPTFEINTKSTPRQLSAACSVPSLQTSDPLPGSVQRCSVVVSQPNKENWCQDHLYNSLGRKGISAKSQPYHRS QSSSSVLINKSMDSINYPSDVGKQQLLSLHRSSRCESHQDLLPDIADSHQQGTEKLSDLTLQDSQKVVVVNRNLPLNAQIATQNYFSNFK ETDGDEDDYVEIKSEEDESELELSHNRRRKSDSKFVDADFSDNVCSGNTLHSLNSPRTPKKPVNSKLGLSPYLTPYNDSDKLNDYLWRGP -------------------------------------------------------------- >6413_6413_6_ARID1B-PLEKHG1_ARID1B_chr6_157256709_ENST00000350026_PLEKHG1_chr6_151089773_ENST00000367328_length(amino acids)=1914AA_BP=269 MAHNAGAAAAAGTHSAKSGGSEAALKEGGSAAALSSSSSSSAAAAAASSSSSSGPGSAMETGLLPNHKLKTVGEAPAAPPHQQHHHHHHA HHHHHHAHHLHHHHALQQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLS KPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSAS AAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGG SSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPP SQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQ QSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQD MSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDYLDCIRDQTKLPLGTEERSALFGNIQDIYHFNSELLQDLENCENDPVAIAECF VSKSEEFHIYTQYCTNYPRSVAVLTECMRNKILAKFFRERQETLKHSLPLGSYLLKPVQRILKYHLLLHEIENHLDKDTEGYDVVLDAID TMQRVAWHINDMKRKHEHAVRLQEIQSLLTNWKGPDLTSYGELVLEGTFRIQRAKNERTLFLFDKLLLITKKRDDTFTYKAHILCGNLML VEVIPKEPLSFSVFHYKNPKLQHTVQAKSQQDKRLWVLHLKRLILENHAAKIPAKAKQAILEMDAIHHPGFCYSPEGGTKALFGSKEGSA PYRLRRKSEPSSRSHKVLKTSETAQDIQKVSREEGSPQLSSARPSPAQRNSQPSSSTMISVLRAGGALRNIWTDHQIRQALFPSRRSPQE NEDDEDDYQMFVPSFSSSDLNSTRLCEDSTSSRPCSWHMGQMESTETSSSGHRIVRRASSAGESNTCPPEIGTSDRTRELQNSPKTEGQE EMTPFGSSIELTIDDIDHVYDNISYEDLKLMVAKREEAESTPSKSARDSVRPKSTPELAFTKRQAGHSKGSLYAQTDGTLSGGEASSQST HELQAVEENIYDTIGLPDPPSLGFKCSSLKRAKRSTFLGLEADFVCCDSLRPFVSQDSLQLSEDEAPYHQATPDHGYLSLLYDSPSGNLS MPHKPVSDKLSEEVDEIWNDLENYIKKNEDKARDRLLAAFPVSKDDVPDRLHAESTPELSRDVGRSVSTLSLPESQALLTPVKSRAGRAS RANCPFEEDLISKEGSFMSLNRLSLASEMPLMDNPYDLANSGLSQTDPENPDLGMEATDKTKSRVFMMARQYSQKIKKANQLLKVKSLEL EQPPASQHQKSMHKDLAAILEEKKQGGPAIGARIAEYSQLYDQIVFRESPLKIQKDGWASPQESSLLRSVSPSQVHHGSGDWLLHSTYSN GELADFCLPPEQDLRSRYPTFEINTKSTPRQLSAACSVPSLQTSDPLPGSVQRCSVVVSQPNKENWCQDHLYNSLGRKGISAKSQPYHRS QSSSSVLINKSMDSINYPSDVGKQQLLSLHRSSRCESHQDLLPDIADSHQQGTEKLSDLTLQDSQKVVVVNRNLPLNAQIATQNYFSNFK ETDGDEDDYVEIKSEEDESELELSHNRRRKSDSKFVDADFSDNVCSGNTLHSLNSPRTPKKPVNSKLGLSPYLTPYNDSDKLNDYLWRGP -------------------------------------------------------------- >6413_6413_7_ARID1B-PLEKHG1_ARID1B_chr6_157256709_ENST00000367148_PLEKHG1_chr6_151089773_ENST00000358517_length(amino acids)=1914AA_BP=269 MAHNAGAAAAAGTHSAKSGGSEAALKEGGSAAALSSSSSSSAAAAAASSSSSSGPGSAMETGLLPNHKLKTVGEAPAAPPHQQHHHHHHA HHHHHHAHHLHHHHALQQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLS KPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSAS AAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGG SSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPP SQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQ QSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQD MSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDYLDCIRDQTKLPLGTEERSALFGNIQDIYHFNSELLQDLENCENDPVAIAECF VSKSEEFHIYTQYCTNYPRSVAVLTECMRNKILAKFFRERQETLKHSLPLGSYLLKPVQRILKYHLLLHEIENHLDKDTEGYDVVLDAID TMQRVAWHINDMKRKHEHAVRLQEIQSLLTNWKGPDLTSYGELVLEGTFRIQRAKNERTLFLFDKLLLITKKRDDTFTYKAHILCGNLML VEVIPKEPLSFSVFHYKNPKLQHTVQAKSQQDKRLWVLHLKRLILENHAAKIPAKAKQAILEMDAIHHPGFCYSPEGGTKALFGSKEGSA PYRLRRKSEPSSRSHKVLKTSETAQDIQKVSREEGSPQLSSARPSPAQRNSQPSSSTMISVLRAGGALRNIWTDHQIRQALFPSRRSPQE NEDDEDDYQMFVPSFSSSDLNSTRLCEDSTSSRPCSWHMGQMESTETSSSGHRIVRRASSAGESNTCPPEIGTSDRTRELQNSPKTEGQE EMTPFGSSIELTIDDIDHVYDNISYEDLKLMVAKREEAESTPSKSARDSVRPKSTPELAFTKRQAGHSKGSLYAQTDGTLSGGEASSQST HELQAVEENIYDTIGLPDPPSLGFKCSSLKRAKRSTFLGLEADFVCCDSLRPFVSQDSLQLSEDEAPYHQATPDHGYLSLLYDSPSGNLS MPHKPVSDKLSEEVDEIWNDLENYIKKNEDKARDRLLAAFPVSKDDVPDRLHAESTPELSRDVGRSVSTLSLPESQALLTPVKSRAGRAS RANCPFEEDLISKEGSFMSLNRLSLASEMPLMDNPYDLANSGLSQTDPENPDLGMEATDKTKSRVFMMARQYSQKIKKANQLLKVKSLEL EQPPASQHQKSMHKDLAAILEEKKQGGPAIGARIAEYSQLYDQIVFRESPLKIQKDGWASPQESSLLRSVSPSQVHHGSGDWLLHSTYSN GELADFCLPPEQDLRSRYPTFEINTKSTPRQLSAACSVPSLQTSDPLPGSVQRCSVVVSQPNKENWCQDHLYNSLGRKGISAKSQPYHRS QSSSSVLINKSMDSINYPSDVGKQQLLSLHRSSRCESHQDLLPDIADSHQQGTEKLSDLTLQDSQKVVVVNRNLPLNAQIATQNYFSNFK ETDGDEDDYVEIKSEEDESELELSHNRRRKSDSKFVDADFSDNVCSGNTLHSLNSPRTPKKPVNSKLGLSPYLTPYNDSDKLNDYLWRGP -------------------------------------------------------------- >6413_6413_8_ARID1B-PLEKHG1_ARID1B_chr6_157256709_ENST00000367148_PLEKHG1_chr6_151089773_ENST00000367328_length(amino acids)=1914AA_BP=269 MAHNAGAAAAAGTHSAKSGGSEAALKEGGSAAALSSSSSSSAAAAAASSSSSSGPGSAMETGLLPNHKLKTVGEAPAAPPHQQHHHHHHA HHHHHHAHHLHHHHALQQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLS KPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSAS AAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGG SSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPP SQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQ QSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQD MSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDYLDCIRDQTKLPLGTEERSALFGNIQDIYHFNSELLQDLENCENDPVAIAECF VSKSEEFHIYTQYCTNYPRSVAVLTECMRNKILAKFFRERQETLKHSLPLGSYLLKPVQRILKYHLLLHEIENHLDKDTEGYDVVLDAID TMQRVAWHINDMKRKHEHAVRLQEIQSLLTNWKGPDLTSYGELVLEGTFRIQRAKNERTLFLFDKLLLITKKRDDTFTYKAHILCGNLML VEVIPKEPLSFSVFHYKNPKLQHTVQAKSQQDKRLWVLHLKRLILENHAAKIPAKAKQAILEMDAIHHPGFCYSPEGGTKALFGSKEGSA PYRLRRKSEPSSRSHKVLKTSETAQDIQKVSREEGSPQLSSARPSPAQRNSQPSSSTMISVLRAGGALRNIWTDHQIRQALFPSRRSPQE NEDDEDDYQMFVPSFSSSDLNSTRLCEDSTSSRPCSWHMGQMESTETSSSGHRIVRRASSAGESNTCPPEIGTSDRTRELQNSPKTEGQE EMTPFGSSIELTIDDIDHVYDNISYEDLKLMVAKREEAESTPSKSARDSVRPKSTPELAFTKRQAGHSKGSLYAQTDGTLSGGEASSQST HELQAVEENIYDTIGLPDPPSLGFKCSSLKRAKRSTFLGLEADFVCCDSLRPFVSQDSLQLSEDEAPYHQATPDHGYLSLLYDSPSGNLS MPHKPVSDKLSEEVDEIWNDLENYIKKNEDKARDRLLAAFPVSKDDVPDRLHAESTPELSRDVGRSVSTLSLPESQALLTPVKSRAGRAS RANCPFEEDLISKEGSFMSLNRLSLASEMPLMDNPYDLANSGLSQTDPENPDLGMEATDKTKSRVFMMARQYSQKIKKANQLLKVKSLEL EQPPASQHQKSMHKDLAAILEEKKQGGPAIGARIAEYSQLYDQIVFRESPLKIQKDGWASPQESSLLRSVSPSQVHHGSGDWLLHSTYSN GELADFCLPPEQDLRSRYPTFEINTKSTPRQLSAACSVPSLQTSDPLPGSVQRCSVVVSQPNKENWCQDHLYNSLGRKGISAKSQPYHRS QSSSSVLINKSMDSINYPSDVGKQQLLSLHRSSRCESHQDLLPDIADSHQQGTEKLSDLTLQDSQKVVVVNRNLPLNAQIATQNYFSNFK ETDGDEDDYVEIKSEEDESELELSHNRRRKSDSKFVDADFSDNVCSGNTLHSLNSPRTPKKPVNSKLGLSPYLTPYNDSDKLNDYLWRGP -------------------------------------------------------------- >6413_6413_9_ARID1B-PLEKHG1_ARID1B_chr6_157256710_ENST00000275248_PLEKHG1_chr6_151089773_ENST00000358517_length(amino acids)=1881AA_BP=236 MSSSSSSSAAAAAASSSSSSGPGSAMETGLLPNHKLKTVGEAPAAPPHQQHHHHHHAHHHHHHAHHLHHHHALQQQLNQFQQQQQQQQQQ QQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQP PVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSR PGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKA AAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQY AAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGM QYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPS SLPDYLDCIRDQTKLPLGTEERSALFGNIQDIYHFNSELLQDLENCENDPVAIAECFVSKSEEFHIYTQYCTNYPRSVAVLTECMRNKIL AKFFRERQETLKHSLPLGSYLLKPVQRILKYHLLLHEIENHLDKDTEGYDVVLDAIDTMQRVAWHINDMKRKHEHAVRLQEIQSLLTNWK GPDLTSYGELVLEGTFRIQRAKNERTLFLFDKLLLITKKRDDTFTYKAHILCGNLMLVEVIPKEPLSFSVFHYKNPKLQHTVQAKSQQDK RLWVLHLKRLILENHAAKIPAKAKQAILEMDAIHHPGFCYSPEGGTKALFGSKEGSAPYRLRRKSEPSSRSHKVLKTSETAQDIQKVSRE EGSPQLSSARPSPAQRNSQPSSSTMISVLRAGGALRNIWTDHQIRQALFPSRRSPQENEDDEDDYQMFVPSFSSSDLNSTRLCEDSTSSR PCSWHMGQMESTETSSSGHRIVRRASSAGESNTCPPEIGTSDRTRELQNSPKTEGQEEMTPFGSSIELTIDDIDHVYDNISYEDLKLMVA KREEAESTPSKSARDSVRPKSTPELAFTKRQAGHSKGSLYAQTDGTLSGGEASSQSTHELQAVEENIYDTIGLPDPPSLGFKCSSLKRAK RSTFLGLEADFVCCDSLRPFVSQDSLQLSEDEAPYHQATPDHGYLSLLYDSPSGNLSMPHKPVSDKLSEEVDEIWNDLENYIKKNEDKAR DRLLAAFPVSKDDVPDRLHAESTPELSRDVGRSVSTLSLPESQALLTPVKSRAGRASRANCPFEEDLISKEGSFMSLNRLSLASEMPLMD NPYDLANSGLSQTDPENPDLGMEATDKTKSRVFMMARQYSQKIKKANQLLKVKSLELEQPPASQHQKSMHKDLAAILEEKKQGGPAIGAR IAEYSQLYDQIVFRESPLKIQKDGWASPQESSLLRSVSPSQVHHGSGDWLLHSTYSNGELADFCLPPEQDLRSRYPTFEINTKSTPRQLS AACSVPSLQTSDPLPGSVQRCSVVVSQPNKENWCQDHLYNSLGRKGISAKSQPYHRSQSSSSVLINKSMDSINYPSDVGKQQLLSLHRSS RCESHQDLLPDIADSHQQGTEKLSDLTLQDSQKVVVVNRNLPLNAQIATQNYFSNFKETDGDEDDYVEIKSEEDESELELSHNRRRKSDS -------------------------------------------------------------- >6413_6413_10_ARID1B-PLEKHG1_ARID1B_chr6_157256710_ENST00000275248_PLEKHG1_chr6_151089773_ENST00000367328_length(amino acids)=1881AA_BP=236 MSSSSSSSAAAAAASSSSSSGPGSAMETGLLPNHKLKTVGEAPAAPPHQQHHHHHHAHHHHHHAHHLHHHHALQQQLNQFQQQQQQQQQQ QQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQP PVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSR PGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKA AAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQY AAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGM QYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPS SLPDYLDCIRDQTKLPLGTEERSALFGNIQDIYHFNSELLQDLENCENDPVAIAECFVSKSEEFHIYTQYCTNYPRSVAVLTECMRNKIL AKFFRERQETLKHSLPLGSYLLKPVQRILKYHLLLHEIENHLDKDTEGYDVVLDAIDTMQRVAWHINDMKRKHEHAVRLQEIQSLLTNWK GPDLTSYGELVLEGTFRIQRAKNERTLFLFDKLLLITKKRDDTFTYKAHILCGNLMLVEVIPKEPLSFSVFHYKNPKLQHTVQAKSQQDK RLWVLHLKRLILENHAAKIPAKAKQAILEMDAIHHPGFCYSPEGGTKALFGSKEGSAPYRLRRKSEPSSRSHKVLKTSETAQDIQKVSRE EGSPQLSSARPSPAQRNSQPSSSTMISVLRAGGALRNIWTDHQIRQALFPSRRSPQENEDDEDDYQMFVPSFSSSDLNSTRLCEDSTSSR PCSWHMGQMESTETSSSGHRIVRRASSAGESNTCPPEIGTSDRTRELQNSPKTEGQEEMTPFGSSIELTIDDIDHVYDNISYEDLKLMVA KREEAESTPSKSARDSVRPKSTPELAFTKRQAGHSKGSLYAQTDGTLSGGEASSQSTHELQAVEENIYDTIGLPDPPSLGFKCSSLKRAK RSTFLGLEADFVCCDSLRPFVSQDSLQLSEDEAPYHQATPDHGYLSLLYDSPSGNLSMPHKPVSDKLSEEVDEIWNDLENYIKKNEDKAR DRLLAAFPVSKDDVPDRLHAESTPELSRDVGRSVSTLSLPESQALLTPVKSRAGRASRANCPFEEDLISKEGSFMSLNRLSLASEMPLMD NPYDLANSGLSQTDPENPDLGMEATDKTKSRVFMMARQYSQKIKKANQLLKVKSLELEQPPASQHQKSMHKDLAAILEEKKQGGPAIGAR IAEYSQLYDQIVFRESPLKIQKDGWASPQESSLLRSVSPSQVHHGSGDWLLHSTYSNGELADFCLPPEQDLRSRYPTFEINTKSTPRQLS AACSVPSLQTSDPLPGSVQRCSVVVSQPNKENWCQDHLYNSLGRKGISAKSQPYHRSQSSSSVLINKSMDSINYPSDVGKQQLLSLHRSS RCESHQDLLPDIADSHQQGTEKLSDLTLQDSQKVVVVNRNLPLNAQIATQNYFSNFKETDGDEDDYVEIKSEEDESELELSHNRRRKSDS -------------------------------------------------------------- >6413_6413_11_ARID1B-PLEKHG1_ARID1B_chr6_157256710_ENST00000275248_PLEKHG1_chr6_151089774_ENST00000358517_length(amino acids)=1881AA_BP=236 MSSSSSSSAAAAAASSSSSSGPGSAMETGLLPNHKLKTVGEAPAAPPHQQHHHHHHAHHHHHHAHHLHHHHALQQQLNQFQQQQQQQQQQ QQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQP PVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSR PGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKA AAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQY AAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGM QYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPS SLPDYLDCIRDQTKLPLGTEERSALFGNIQDIYHFNSELLQDLENCENDPVAIAECFVSKSEEFHIYTQYCTNYPRSVAVLTECMRNKIL AKFFRERQETLKHSLPLGSYLLKPVQRILKYHLLLHEIENHLDKDTEGYDVVLDAIDTMQRVAWHINDMKRKHEHAVRLQEIQSLLTNWK GPDLTSYGELVLEGTFRIQRAKNERTLFLFDKLLLITKKRDDTFTYKAHILCGNLMLVEVIPKEPLSFSVFHYKNPKLQHTVQAKSQQDK RLWVLHLKRLILENHAAKIPAKAKQAILEMDAIHHPGFCYSPEGGTKALFGSKEGSAPYRLRRKSEPSSRSHKVLKTSETAQDIQKVSRE EGSPQLSSARPSPAQRNSQPSSSTMISVLRAGGALRNIWTDHQIRQALFPSRRSPQENEDDEDDYQMFVPSFSSSDLNSTRLCEDSTSSR PCSWHMGQMESTETSSSGHRIVRRASSAGESNTCPPEIGTSDRTRELQNSPKTEGQEEMTPFGSSIELTIDDIDHVYDNISYEDLKLMVA KREEAESTPSKSARDSVRPKSTPELAFTKRQAGHSKGSLYAQTDGTLSGGEASSQSTHELQAVEENIYDTIGLPDPPSLGFKCSSLKRAK RSTFLGLEADFVCCDSLRPFVSQDSLQLSEDEAPYHQATPDHGYLSLLYDSPSGNLSMPHKPVSDKLSEEVDEIWNDLENYIKKNEDKAR DRLLAAFPVSKDDVPDRLHAESTPELSRDVGRSVSTLSLPESQALLTPVKSRAGRASRANCPFEEDLISKEGSFMSLNRLSLASEMPLMD NPYDLANSGLSQTDPENPDLGMEATDKTKSRVFMMARQYSQKIKKANQLLKVKSLELEQPPASQHQKSMHKDLAAILEEKKQGGPAIGAR IAEYSQLYDQIVFRESPLKIQKDGWASPQESSLLRSVSPSQVHHGSGDWLLHSTYSNGELADFCLPPEQDLRSRYPTFEINTKSTPRQLS AACSVPSLQTSDPLPGSVQRCSVVVSQPNKENWCQDHLYNSLGRKGISAKSQPYHRSQSSSSVLINKSMDSINYPSDVGKQQLLSLHRSS RCESHQDLLPDIADSHQQGTEKLSDLTLQDSQKVVVVNRNLPLNAQIATQNYFSNFKETDGDEDDYVEIKSEEDESELELSHNRRRKSDS -------------------------------------------------------------- >6413_6413_12_ARID1B-PLEKHG1_ARID1B_chr6_157256710_ENST00000275248_PLEKHG1_chr6_151089774_ENST00000367328_length(amino acids)=1881AA_BP=236 MSSSSSSSAAAAAASSSSSSGPGSAMETGLLPNHKLKTVGEAPAAPPHQQHHHHHHAHHHHHHAHHLHHHHALQQQLNQFQQQQQQQQQQ QQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQP PVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSR PGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKA AAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQY AAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGM QYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPS SLPDYLDCIRDQTKLPLGTEERSALFGNIQDIYHFNSELLQDLENCENDPVAIAECFVSKSEEFHIYTQYCTNYPRSVAVLTECMRNKIL AKFFRERQETLKHSLPLGSYLLKPVQRILKYHLLLHEIENHLDKDTEGYDVVLDAIDTMQRVAWHINDMKRKHEHAVRLQEIQSLLTNWK GPDLTSYGELVLEGTFRIQRAKNERTLFLFDKLLLITKKRDDTFTYKAHILCGNLMLVEVIPKEPLSFSVFHYKNPKLQHTVQAKSQQDK RLWVLHLKRLILENHAAKIPAKAKQAILEMDAIHHPGFCYSPEGGTKALFGSKEGSAPYRLRRKSEPSSRSHKVLKTSETAQDIQKVSRE EGSPQLSSARPSPAQRNSQPSSSTMISVLRAGGALRNIWTDHQIRQALFPSRRSPQENEDDEDDYQMFVPSFSSSDLNSTRLCEDSTSSR PCSWHMGQMESTETSSSGHRIVRRASSAGESNTCPPEIGTSDRTRELQNSPKTEGQEEMTPFGSSIELTIDDIDHVYDNISYEDLKLMVA KREEAESTPSKSARDSVRPKSTPELAFTKRQAGHSKGSLYAQTDGTLSGGEASSQSTHELQAVEENIYDTIGLPDPPSLGFKCSSLKRAK RSTFLGLEADFVCCDSLRPFVSQDSLQLSEDEAPYHQATPDHGYLSLLYDSPSGNLSMPHKPVSDKLSEEVDEIWNDLENYIKKNEDKAR DRLLAAFPVSKDDVPDRLHAESTPELSRDVGRSVSTLSLPESQALLTPVKSRAGRASRANCPFEEDLISKEGSFMSLNRLSLASEMPLMD NPYDLANSGLSQTDPENPDLGMEATDKTKSRVFMMARQYSQKIKKANQLLKVKSLELEQPPASQHQKSMHKDLAAILEEKKQGGPAIGAR IAEYSQLYDQIVFRESPLKIQKDGWASPQESSLLRSVSPSQVHHGSGDWLLHSTYSNGELADFCLPPEQDLRSRYPTFEINTKSTPRQLS AACSVPSLQTSDPLPGSVQRCSVVVSQPNKENWCQDHLYNSLGRKGISAKSQPYHRSQSSSSVLINKSMDSINYPSDVGKQQLLSLHRSS RCESHQDLLPDIADSHQQGTEKLSDLTLQDSQKVVVVNRNLPLNAQIATQNYFSNFKETDGDEDDYVEIKSEEDESELELSHNRRRKSDS -------------------------------------------------------------- >6413_6413_13_ARID1B-PLEKHG1_ARID1B_chr6_157256710_ENST00000346085_PLEKHG1_chr6_151089773_ENST00000358517_length(amino acids)=1927AA_BP=269 MAHNAGAAAAAGTHSAKSGGSEAALKEGGSAAALSSSSSSSAAAAAASSSSSSGPGSAMETGLLPNHKLKTVGEAPAAPPHQQHHHHHHA HHHHHHAHHLHHHHALQQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLS KPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSAS AAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGG SSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPP SQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQ QSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQDSGDATWKETFWLMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYL PSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDYLDCIRDQTKLPLGTEERSALFGNIQDIYHFNSELLQDLE NCENDPVAIAECFVSKSEEFHIYTQYCTNYPRSVAVLTECMRNKILAKFFRERQETLKHSLPLGSYLLKPVQRILKYHLLLHEIENHLDK DTEGYDVVLDAIDTMQRVAWHINDMKRKHEHAVRLQEIQSLLTNWKGPDLTSYGELVLEGTFRIQRAKNERTLFLFDKLLLITKKRDDTF TYKAHILCGNLMLVEVIPKEPLSFSVFHYKNPKLQHTVQAKSQQDKRLWVLHLKRLILENHAAKIPAKAKQAILEMDAIHHPGFCYSPEG GTKALFGSKEGSAPYRLRRKSEPSSRSHKVLKTSETAQDIQKVSREEGSPQLSSARPSPAQRNSQPSSSTMISVLRAGGALRNIWTDHQI RQALFPSRRSPQENEDDEDDYQMFVPSFSSSDLNSTRLCEDSTSSRPCSWHMGQMESTETSSSGHRIVRRASSAGESNTCPPEIGTSDRT RELQNSPKTEGQEEMTPFGSSIELTIDDIDHVYDNISYEDLKLMVAKREEAESTPSKSARDSVRPKSTPELAFTKRQAGHSKGSLYAQTD GTLSGGEASSQSTHELQAVEENIYDTIGLPDPPSLGFKCSSLKRAKRSTFLGLEADFVCCDSLRPFVSQDSLQLSEDEAPYHQATPDHGY LSLLYDSPSGNLSMPHKPVSDKLSEEVDEIWNDLENYIKKNEDKARDRLLAAFPVSKDDVPDRLHAESTPELSRDVGRSVSTLSLPESQA LLTPVKSRAGRASRANCPFEEDLISKEGSFMSLNRLSLASEMPLMDNPYDLANSGLSQTDPENPDLGMEATDKTKSRVFMMARQYSQKIK KANQLLKVKSLELEQPPASQHQKSMHKDLAAILEEKKQGGPAIGARIAEYSQLYDQIVFRESPLKIQKDGWASPQESSLLRSVSPSQVHH GSGDWLLHSTYSNGELADFCLPPEQDLRSRYPTFEINTKSTPRQLSAACSVPSLQTSDPLPGSVQRCSVVVSQPNKENWCQDHLYNSLGR KGISAKSQPYHRSQSSSSVLINKSMDSINYPSDVGKQQLLSLHRSSRCESHQDLLPDIADSHQQGTEKLSDLTLQDSQKVVVVNRNLPLN AQIATQNYFSNFKETDGDEDDYVEIKSEEDESELELSHNRRRKSDSKFVDADFSDNVCSGNTLHSLNSPRTPKKPVNSKLGLSPYLTPYN -------------------------------------------------------------- >6413_6413_14_ARID1B-PLEKHG1_ARID1B_chr6_157256710_ENST00000346085_PLEKHG1_chr6_151089773_ENST00000367328_length(amino acids)=1927AA_BP=269 MAHNAGAAAAAGTHSAKSGGSEAALKEGGSAAALSSSSSSSAAAAAASSSSSSGPGSAMETGLLPNHKLKTVGEAPAAPPHQQHHHHHHA HHHHHHAHHLHHHHALQQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLS KPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSAS AAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGG SSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPP SQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQ QSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQDSGDATWKETFWLMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYL PSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDYLDCIRDQTKLPLGTEERSALFGNIQDIYHFNSELLQDLE NCENDPVAIAECFVSKSEEFHIYTQYCTNYPRSVAVLTECMRNKILAKFFRERQETLKHSLPLGSYLLKPVQRILKYHLLLHEIENHLDK DTEGYDVVLDAIDTMQRVAWHINDMKRKHEHAVRLQEIQSLLTNWKGPDLTSYGELVLEGTFRIQRAKNERTLFLFDKLLLITKKRDDTF TYKAHILCGNLMLVEVIPKEPLSFSVFHYKNPKLQHTVQAKSQQDKRLWVLHLKRLILENHAAKIPAKAKQAILEMDAIHHPGFCYSPEG GTKALFGSKEGSAPYRLRRKSEPSSRSHKVLKTSETAQDIQKVSREEGSPQLSSARPSPAQRNSQPSSSTMISVLRAGGALRNIWTDHQI RQALFPSRRSPQENEDDEDDYQMFVPSFSSSDLNSTRLCEDSTSSRPCSWHMGQMESTETSSSGHRIVRRASSAGESNTCPPEIGTSDRT RELQNSPKTEGQEEMTPFGSSIELTIDDIDHVYDNISYEDLKLMVAKREEAESTPSKSARDSVRPKSTPELAFTKRQAGHSKGSLYAQTD GTLSGGEASSQSTHELQAVEENIYDTIGLPDPPSLGFKCSSLKRAKRSTFLGLEADFVCCDSLRPFVSQDSLQLSEDEAPYHQATPDHGY LSLLYDSPSGNLSMPHKPVSDKLSEEVDEIWNDLENYIKKNEDKARDRLLAAFPVSKDDVPDRLHAESTPELSRDVGRSVSTLSLPESQA LLTPVKSRAGRASRANCPFEEDLISKEGSFMSLNRLSLASEMPLMDNPYDLANSGLSQTDPENPDLGMEATDKTKSRVFMMARQYSQKIK KANQLLKVKSLELEQPPASQHQKSMHKDLAAILEEKKQGGPAIGARIAEYSQLYDQIVFRESPLKIQKDGWASPQESSLLRSVSPSQVHH GSGDWLLHSTYSNGELADFCLPPEQDLRSRYPTFEINTKSTPRQLSAACSVPSLQTSDPLPGSVQRCSVVVSQPNKENWCQDHLYNSLGR KGISAKSQPYHRSQSSSSVLINKSMDSINYPSDVGKQQLLSLHRSSRCESHQDLLPDIADSHQQGTEKLSDLTLQDSQKVVVVNRNLPLN AQIATQNYFSNFKETDGDEDDYVEIKSEEDESELELSHNRRRKSDSKFVDADFSDNVCSGNTLHSLNSPRTPKKPVNSKLGLSPYLTPYN -------------------------------------------------------------- >6413_6413_15_ARID1B-PLEKHG1_ARID1B_chr6_157256710_ENST00000346085_PLEKHG1_chr6_151089774_ENST00000358517_length(amino acids)=1927AA_BP=269 MAHNAGAAAAAGTHSAKSGGSEAALKEGGSAAALSSSSSSSAAAAAASSSSSSGPGSAMETGLLPNHKLKTVGEAPAAPPHQQHHHHHHA HHHHHHAHHLHHHHALQQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLS KPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSAS AAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGG SSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPP SQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQ QSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQDSGDATWKETFWLMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYL PSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDYLDCIRDQTKLPLGTEERSALFGNIQDIYHFNSELLQDLE NCENDPVAIAECFVSKSEEFHIYTQYCTNYPRSVAVLTECMRNKILAKFFRERQETLKHSLPLGSYLLKPVQRILKYHLLLHEIENHLDK DTEGYDVVLDAIDTMQRVAWHINDMKRKHEHAVRLQEIQSLLTNWKGPDLTSYGELVLEGTFRIQRAKNERTLFLFDKLLLITKKRDDTF TYKAHILCGNLMLVEVIPKEPLSFSVFHYKNPKLQHTVQAKSQQDKRLWVLHLKRLILENHAAKIPAKAKQAILEMDAIHHPGFCYSPEG GTKALFGSKEGSAPYRLRRKSEPSSRSHKVLKTSETAQDIQKVSREEGSPQLSSARPSPAQRNSQPSSSTMISVLRAGGALRNIWTDHQI RQALFPSRRSPQENEDDEDDYQMFVPSFSSSDLNSTRLCEDSTSSRPCSWHMGQMESTETSSSGHRIVRRASSAGESNTCPPEIGTSDRT RELQNSPKTEGQEEMTPFGSSIELTIDDIDHVYDNISYEDLKLMVAKREEAESTPSKSARDSVRPKSTPELAFTKRQAGHSKGSLYAQTD GTLSGGEASSQSTHELQAVEENIYDTIGLPDPPSLGFKCSSLKRAKRSTFLGLEADFVCCDSLRPFVSQDSLQLSEDEAPYHQATPDHGY LSLLYDSPSGNLSMPHKPVSDKLSEEVDEIWNDLENYIKKNEDKARDRLLAAFPVSKDDVPDRLHAESTPELSRDVGRSVSTLSLPESQA LLTPVKSRAGRASRANCPFEEDLISKEGSFMSLNRLSLASEMPLMDNPYDLANSGLSQTDPENPDLGMEATDKTKSRVFMMARQYSQKIK KANQLLKVKSLELEQPPASQHQKSMHKDLAAILEEKKQGGPAIGARIAEYSQLYDQIVFRESPLKIQKDGWASPQESSLLRSVSPSQVHH GSGDWLLHSTYSNGELADFCLPPEQDLRSRYPTFEINTKSTPRQLSAACSVPSLQTSDPLPGSVQRCSVVVSQPNKENWCQDHLYNSLGR KGISAKSQPYHRSQSSSSVLINKSMDSINYPSDVGKQQLLSLHRSSRCESHQDLLPDIADSHQQGTEKLSDLTLQDSQKVVVVNRNLPLN AQIATQNYFSNFKETDGDEDDYVEIKSEEDESELELSHNRRRKSDSKFVDADFSDNVCSGNTLHSLNSPRTPKKPVNSKLGLSPYLTPYN -------------------------------------------------------------- >6413_6413_16_ARID1B-PLEKHG1_ARID1B_chr6_157256710_ENST00000346085_PLEKHG1_chr6_151089774_ENST00000367328_length(amino acids)=1927AA_BP=269 MAHNAGAAAAAGTHSAKSGGSEAALKEGGSAAALSSSSSSSAAAAAASSSSSSGPGSAMETGLLPNHKLKTVGEAPAAPPHQQHHHHHHA HHHHHHAHHLHHHHALQQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLS KPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSAS AAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGG SSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPP SQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQ QSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQDSGDATWKETFWLMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYL PSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDYLDCIRDQTKLPLGTEERSALFGNIQDIYHFNSELLQDLE NCENDPVAIAECFVSKSEEFHIYTQYCTNYPRSVAVLTECMRNKILAKFFRERQETLKHSLPLGSYLLKPVQRILKYHLLLHEIENHLDK DTEGYDVVLDAIDTMQRVAWHINDMKRKHEHAVRLQEIQSLLTNWKGPDLTSYGELVLEGTFRIQRAKNERTLFLFDKLLLITKKRDDTF TYKAHILCGNLMLVEVIPKEPLSFSVFHYKNPKLQHTVQAKSQQDKRLWVLHLKRLILENHAAKIPAKAKQAILEMDAIHHPGFCYSPEG GTKALFGSKEGSAPYRLRRKSEPSSRSHKVLKTSETAQDIQKVSREEGSPQLSSARPSPAQRNSQPSSSTMISVLRAGGALRNIWTDHQI RQALFPSRRSPQENEDDEDDYQMFVPSFSSSDLNSTRLCEDSTSSRPCSWHMGQMESTETSSSGHRIVRRASSAGESNTCPPEIGTSDRT RELQNSPKTEGQEEMTPFGSSIELTIDDIDHVYDNISYEDLKLMVAKREEAESTPSKSARDSVRPKSTPELAFTKRQAGHSKGSLYAQTD GTLSGGEASSQSTHELQAVEENIYDTIGLPDPPSLGFKCSSLKRAKRSTFLGLEADFVCCDSLRPFVSQDSLQLSEDEAPYHQATPDHGY LSLLYDSPSGNLSMPHKPVSDKLSEEVDEIWNDLENYIKKNEDKARDRLLAAFPVSKDDVPDRLHAESTPELSRDVGRSVSTLSLPESQA LLTPVKSRAGRASRANCPFEEDLISKEGSFMSLNRLSLASEMPLMDNPYDLANSGLSQTDPENPDLGMEATDKTKSRVFMMARQYSQKIK KANQLLKVKSLELEQPPASQHQKSMHKDLAAILEEKKQGGPAIGARIAEYSQLYDQIVFRESPLKIQKDGWASPQESSLLRSVSPSQVHH GSGDWLLHSTYSNGELADFCLPPEQDLRSRYPTFEINTKSTPRQLSAACSVPSLQTSDPLPGSVQRCSVVVSQPNKENWCQDHLYNSLGR KGISAKSQPYHRSQSSSSVLINKSMDSINYPSDVGKQQLLSLHRSSRCESHQDLLPDIADSHQQGTEKLSDLTLQDSQKVVVVNRNLPLN AQIATQNYFSNFKETDGDEDDYVEIKSEEDESELELSHNRRRKSDSKFVDADFSDNVCSGNTLHSLNSPRTPKKPVNSKLGLSPYLTPYN -------------------------------------------------------------- >6413_6413_17_ARID1B-PLEKHG1_ARID1B_chr6_157256710_ENST00000350026_PLEKHG1_chr6_151089773_ENST00000358517_length(amino acids)=1914AA_BP=269 MAHNAGAAAAAGTHSAKSGGSEAALKEGGSAAALSSSSSSSAAAAAASSSSSSGPGSAMETGLLPNHKLKTVGEAPAAPPHQQHHHHHHA HHHHHHAHHLHHHHALQQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLS KPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSAS AAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGG SSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPP SQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQ QSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQD MSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDYLDCIRDQTKLPLGTEERSALFGNIQDIYHFNSELLQDLENCENDPVAIAECF VSKSEEFHIYTQYCTNYPRSVAVLTECMRNKILAKFFRERQETLKHSLPLGSYLLKPVQRILKYHLLLHEIENHLDKDTEGYDVVLDAID TMQRVAWHINDMKRKHEHAVRLQEIQSLLTNWKGPDLTSYGELVLEGTFRIQRAKNERTLFLFDKLLLITKKRDDTFTYKAHILCGNLML VEVIPKEPLSFSVFHYKNPKLQHTVQAKSQQDKRLWVLHLKRLILENHAAKIPAKAKQAILEMDAIHHPGFCYSPEGGTKALFGSKEGSA PYRLRRKSEPSSRSHKVLKTSETAQDIQKVSREEGSPQLSSARPSPAQRNSQPSSSTMISVLRAGGALRNIWTDHQIRQALFPSRRSPQE NEDDEDDYQMFVPSFSSSDLNSTRLCEDSTSSRPCSWHMGQMESTETSSSGHRIVRRASSAGESNTCPPEIGTSDRTRELQNSPKTEGQE EMTPFGSSIELTIDDIDHVYDNISYEDLKLMVAKREEAESTPSKSARDSVRPKSTPELAFTKRQAGHSKGSLYAQTDGTLSGGEASSQST HELQAVEENIYDTIGLPDPPSLGFKCSSLKRAKRSTFLGLEADFVCCDSLRPFVSQDSLQLSEDEAPYHQATPDHGYLSLLYDSPSGNLS MPHKPVSDKLSEEVDEIWNDLENYIKKNEDKARDRLLAAFPVSKDDVPDRLHAESTPELSRDVGRSVSTLSLPESQALLTPVKSRAGRAS RANCPFEEDLISKEGSFMSLNRLSLASEMPLMDNPYDLANSGLSQTDPENPDLGMEATDKTKSRVFMMARQYSQKIKKANQLLKVKSLEL EQPPASQHQKSMHKDLAAILEEKKQGGPAIGARIAEYSQLYDQIVFRESPLKIQKDGWASPQESSLLRSVSPSQVHHGSGDWLLHSTYSN GELADFCLPPEQDLRSRYPTFEINTKSTPRQLSAACSVPSLQTSDPLPGSVQRCSVVVSQPNKENWCQDHLYNSLGRKGISAKSQPYHRS QSSSSVLINKSMDSINYPSDVGKQQLLSLHRSSRCESHQDLLPDIADSHQQGTEKLSDLTLQDSQKVVVVNRNLPLNAQIATQNYFSNFK ETDGDEDDYVEIKSEEDESELELSHNRRRKSDSKFVDADFSDNVCSGNTLHSLNSPRTPKKPVNSKLGLSPYLTPYNDSDKLNDYLWRGP -------------------------------------------------------------- >6413_6413_18_ARID1B-PLEKHG1_ARID1B_chr6_157256710_ENST00000350026_PLEKHG1_chr6_151089773_ENST00000367328_length(amino acids)=1914AA_BP=269 MAHNAGAAAAAGTHSAKSGGSEAALKEGGSAAALSSSSSSSAAAAAASSSSSSGPGSAMETGLLPNHKLKTVGEAPAAPPHQQHHHHHHA HHHHHHAHHLHHHHALQQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLS KPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSAS AAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGG SSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPP SQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQ QSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQD MSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDYLDCIRDQTKLPLGTEERSALFGNIQDIYHFNSELLQDLENCENDPVAIAECF VSKSEEFHIYTQYCTNYPRSVAVLTECMRNKILAKFFRERQETLKHSLPLGSYLLKPVQRILKYHLLLHEIENHLDKDTEGYDVVLDAID TMQRVAWHINDMKRKHEHAVRLQEIQSLLTNWKGPDLTSYGELVLEGTFRIQRAKNERTLFLFDKLLLITKKRDDTFTYKAHILCGNLML VEVIPKEPLSFSVFHYKNPKLQHTVQAKSQQDKRLWVLHLKRLILENHAAKIPAKAKQAILEMDAIHHPGFCYSPEGGTKALFGSKEGSA PYRLRRKSEPSSRSHKVLKTSETAQDIQKVSREEGSPQLSSARPSPAQRNSQPSSSTMISVLRAGGALRNIWTDHQIRQALFPSRRSPQE NEDDEDDYQMFVPSFSSSDLNSTRLCEDSTSSRPCSWHMGQMESTETSSSGHRIVRRASSAGESNTCPPEIGTSDRTRELQNSPKTEGQE EMTPFGSSIELTIDDIDHVYDNISYEDLKLMVAKREEAESTPSKSARDSVRPKSTPELAFTKRQAGHSKGSLYAQTDGTLSGGEASSQST HELQAVEENIYDTIGLPDPPSLGFKCSSLKRAKRSTFLGLEADFVCCDSLRPFVSQDSLQLSEDEAPYHQATPDHGYLSLLYDSPSGNLS MPHKPVSDKLSEEVDEIWNDLENYIKKNEDKARDRLLAAFPVSKDDVPDRLHAESTPELSRDVGRSVSTLSLPESQALLTPVKSRAGRAS RANCPFEEDLISKEGSFMSLNRLSLASEMPLMDNPYDLANSGLSQTDPENPDLGMEATDKTKSRVFMMARQYSQKIKKANQLLKVKSLEL EQPPASQHQKSMHKDLAAILEEKKQGGPAIGARIAEYSQLYDQIVFRESPLKIQKDGWASPQESSLLRSVSPSQVHHGSGDWLLHSTYSN GELADFCLPPEQDLRSRYPTFEINTKSTPRQLSAACSVPSLQTSDPLPGSVQRCSVVVSQPNKENWCQDHLYNSLGRKGISAKSQPYHRS QSSSSVLINKSMDSINYPSDVGKQQLLSLHRSSRCESHQDLLPDIADSHQQGTEKLSDLTLQDSQKVVVVNRNLPLNAQIATQNYFSNFK ETDGDEDDYVEIKSEEDESELELSHNRRRKSDSKFVDADFSDNVCSGNTLHSLNSPRTPKKPVNSKLGLSPYLTPYNDSDKLNDYLWRGP -------------------------------------------------------------- >6413_6413_19_ARID1B-PLEKHG1_ARID1B_chr6_157256710_ENST00000350026_PLEKHG1_chr6_151089774_ENST00000358517_length(amino acids)=1914AA_BP=269 MAHNAGAAAAAGTHSAKSGGSEAALKEGGSAAALSSSSSSSAAAAAASSSSSSGPGSAMETGLLPNHKLKTVGEAPAAPPHQQHHHHHHA HHHHHHAHHLHHHHALQQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLS KPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSAS AAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGG SSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPP SQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQ QSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQD MSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDYLDCIRDQTKLPLGTEERSALFGNIQDIYHFNSELLQDLENCENDPVAIAECF VSKSEEFHIYTQYCTNYPRSVAVLTECMRNKILAKFFRERQETLKHSLPLGSYLLKPVQRILKYHLLLHEIENHLDKDTEGYDVVLDAID TMQRVAWHINDMKRKHEHAVRLQEIQSLLTNWKGPDLTSYGELVLEGTFRIQRAKNERTLFLFDKLLLITKKRDDTFTYKAHILCGNLML VEVIPKEPLSFSVFHYKNPKLQHTVQAKSQQDKRLWVLHLKRLILENHAAKIPAKAKQAILEMDAIHHPGFCYSPEGGTKALFGSKEGSA PYRLRRKSEPSSRSHKVLKTSETAQDIQKVSREEGSPQLSSARPSPAQRNSQPSSSTMISVLRAGGALRNIWTDHQIRQALFPSRRSPQE NEDDEDDYQMFVPSFSSSDLNSTRLCEDSTSSRPCSWHMGQMESTETSSSGHRIVRRASSAGESNTCPPEIGTSDRTRELQNSPKTEGQE EMTPFGSSIELTIDDIDHVYDNISYEDLKLMVAKREEAESTPSKSARDSVRPKSTPELAFTKRQAGHSKGSLYAQTDGTLSGGEASSQST HELQAVEENIYDTIGLPDPPSLGFKCSSLKRAKRSTFLGLEADFVCCDSLRPFVSQDSLQLSEDEAPYHQATPDHGYLSLLYDSPSGNLS MPHKPVSDKLSEEVDEIWNDLENYIKKNEDKARDRLLAAFPVSKDDVPDRLHAESTPELSRDVGRSVSTLSLPESQALLTPVKSRAGRAS RANCPFEEDLISKEGSFMSLNRLSLASEMPLMDNPYDLANSGLSQTDPENPDLGMEATDKTKSRVFMMARQYSQKIKKANQLLKVKSLEL EQPPASQHQKSMHKDLAAILEEKKQGGPAIGARIAEYSQLYDQIVFRESPLKIQKDGWASPQESSLLRSVSPSQVHHGSGDWLLHSTYSN GELADFCLPPEQDLRSRYPTFEINTKSTPRQLSAACSVPSLQTSDPLPGSVQRCSVVVSQPNKENWCQDHLYNSLGRKGISAKSQPYHRS QSSSSVLINKSMDSINYPSDVGKQQLLSLHRSSRCESHQDLLPDIADSHQQGTEKLSDLTLQDSQKVVVVNRNLPLNAQIATQNYFSNFK ETDGDEDDYVEIKSEEDESELELSHNRRRKSDSKFVDADFSDNVCSGNTLHSLNSPRTPKKPVNSKLGLSPYLTPYNDSDKLNDYLWRGP -------------------------------------------------------------- >6413_6413_20_ARID1B-PLEKHG1_ARID1B_chr6_157256710_ENST00000350026_PLEKHG1_chr6_151089774_ENST00000367328_length(amino acids)=1914AA_BP=269 MAHNAGAAAAAGTHSAKSGGSEAALKEGGSAAALSSSSSSSAAAAAASSSSSSGPGSAMETGLLPNHKLKTVGEAPAAPPHQQHHHHHHA HHHHHHAHHLHHHHALQQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLS KPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSAS AAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGG SSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPP SQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQ QSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQD MSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDYLDCIRDQTKLPLGTEERSALFGNIQDIYHFNSELLQDLENCENDPVAIAECF VSKSEEFHIYTQYCTNYPRSVAVLTECMRNKILAKFFRERQETLKHSLPLGSYLLKPVQRILKYHLLLHEIENHLDKDTEGYDVVLDAID TMQRVAWHINDMKRKHEHAVRLQEIQSLLTNWKGPDLTSYGELVLEGTFRIQRAKNERTLFLFDKLLLITKKRDDTFTYKAHILCGNLML VEVIPKEPLSFSVFHYKNPKLQHTVQAKSQQDKRLWVLHLKRLILENHAAKIPAKAKQAILEMDAIHHPGFCYSPEGGTKALFGSKEGSA PYRLRRKSEPSSRSHKVLKTSETAQDIQKVSREEGSPQLSSARPSPAQRNSQPSSSTMISVLRAGGALRNIWTDHQIRQALFPSRRSPQE NEDDEDDYQMFVPSFSSSDLNSTRLCEDSTSSRPCSWHMGQMESTETSSSGHRIVRRASSAGESNTCPPEIGTSDRTRELQNSPKTEGQE EMTPFGSSIELTIDDIDHVYDNISYEDLKLMVAKREEAESTPSKSARDSVRPKSTPELAFTKRQAGHSKGSLYAQTDGTLSGGEASSQST HELQAVEENIYDTIGLPDPPSLGFKCSSLKRAKRSTFLGLEADFVCCDSLRPFVSQDSLQLSEDEAPYHQATPDHGYLSLLYDSPSGNLS MPHKPVSDKLSEEVDEIWNDLENYIKKNEDKARDRLLAAFPVSKDDVPDRLHAESTPELSRDVGRSVSTLSLPESQALLTPVKSRAGRAS RANCPFEEDLISKEGSFMSLNRLSLASEMPLMDNPYDLANSGLSQTDPENPDLGMEATDKTKSRVFMMARQYSQKIKKANQLLKVKSLEL EQPPASQHQKSMHKDLAAILEEKKQGGPAIGARIAEYSQLYDQIVFRESPLKIQKDGWASPQESSLLRSVSPSQVHHGSGDWLLHSTYSN GELADFCLPPEQDLRSRYPTFEINTKSTPRQLSAACSVPSLQTSDPLPGSVQRCSVVVSQPNKENWCQDHLYNSLGRKGISAKSQPYHRS QSSSSVLINKSMDSINYPSDVGKQQLLSLHRSSRCESHQDLLPDIADSHQQGTEKLSDLTLQDSQKVVVVNRNLPLNAQIATQNYFSNFK ETDGDEDDYVEIKSEEDESELELSHNRRRKSDSKFVDADFSDNVCSGNTLHSLNSPRTPKKPVNSKLGLSPYLTPYNDSDKLNDYLWRGP -------------------------------------------------------------- >6413_6413_21_ARID1B-PLEKHG1_ARID1B_chr6_157256710_ENST00000367148_PLEKHG1_chr6_151089773_ENST00000358517_length(amino acids)=1914AA_BP=269 MAHNAGAAAAAGTHSAKSGGSEAALKEGGSAAALSSSSSSSAAAAAASSSSSSGPGSAMETGLLPNHKLKTVGEAPAAPPHQQHHHHHHA HHHHHHAHHLHHHHALQQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLS KPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSAS AAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGG SSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPP SQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQ QSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQD MSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDYLDCIRDQTKLPLGTEERSALFGNIQDIYHFNSELLQDLENCENDPVAIAECF VSKSEEFHIYTQYCTNYPRSVAVLTECMRNKILAKFFRERQETLKHSLPLGSYLLKPVQRILKYHLLLHEIENHLDKDTEGYDVVLDAID TMQRVAWHINDMKRKHEHAVRLQEIQSLLTNWKGPDLTSYGELVLEGTFRIQRAKNERTLFLFDKLLLITKKRDDTFTYKAHILCGNLML VEVIPKEPLSFSVFHYKNPKLQHTVQAKSQQDKRLWVLHLKRLILENHAAKIPAKAKQAILEMDAIHHPGFCYSPEGGTKALFGSKEGSA PYRLRRKSEPSSRSHKVLKTSETAQDIQKVSREEGSPQLSSARPSPAQRNSQPSSSTMISVLRAGGALRNIWTDHQIRQALFPSRRSPQE NEDDEDDYQMFVPSFSSSDLNSTRLCEDSTSSRPCSWHMGQMESTETSSSGHRIVRRASSAGESNTCPPEIGTSDRTRELQNSPKTEGQE EMTPFGSSIELTIDDIDHVYDNISYEDLKLMVAKREEAESTPSKSARDSVRPKSTPELAFTKRQAGHSKGSLYAQTDGTLSGGEASSQST HELQAVEENIYDTIGLPDPPSLGFKCSSLKRAKRSTFLGLEADFVCCDSLRPFVSQDSLQLSEDEAPYHQATPDHGYLSLLYDSPSGNLS MPHKPVSDKLSEEVDEIWNDLENYIKKNEDKARDRLLAAFPVSKDDVPDRLHAESTPELSRDVGRSVSTLSLPESQALLTPVKSRAGRAS RANCPFEEDLISKEGSFMSLNRLSLASEMPLMDNPYDLANSGLSQTDPENPDLGMEATDKTKSRVFMMARQYSQKIKKANQLLKVKSLEL EQPPASQHQKSMHKDLAAILEEKKQGGPAIGARIAEYSQLYDQIVFRESPLKIQKDGWASPQESSLLRSVSPSQVHHGSGDWLLHSTYSN GELADFCLPPEQDLRSRYPTFEINTKSTPRQLSAACSVPSLQTSDPLPGSVQRCSVVVSQPNKENWCQDHLYNSLGRKGISAKSQPYHRS QSSSSVLINKSMDSINYPSDVGKQQLLSLHRSSRCESHQDLLPDIADSHQQGTEKLSDLTLQDSQKVVVVNRNLPLNAQIATQNYFSNFK ETDGDEDDYVEIKSEEDESELELSHNRRRKSDSKFVDADFSDNVCSGNTLHSLNSPRTPKKPVNSKLGLSPYLTPYNDSDKLNDYLWRGP -------------------------------------------------------------- >6413_6413_22_ARID1B-PLEKHG1_ARID1B_chr6_157256710_ENST00000367148_PLEKHG1_chr6_151089773_ENST00000367328_length(amino acids)=1914AA_BP=269 MAHNAGAAAAAGTHSAKSGGSEAALKEGGSAAALSSSSSSSAAAAAASSSSSSGPGSAMETGLLPNHKLKTVGEAPAAPPHQQHHHHHHA HHHHHHAHHLHHHHALQQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLS KPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSAS AAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGG SSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPP SQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQ QSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQD MSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDYLDCIRDQTKLPLGTEERSALFGNIQDIYHFNSELLQDLENCENDPVAIAECF VSKSEEFHIYTQYCTNYPRSVAVLTECMRNKILAKFFRERQETLKHSLPLGSYLLKPVQRILKYHLLLHEIENHLDKDTEGYDVVLDAID TMQRVAWHINDMKRKHEHAVRLQEIQSLLTNWKGPDLTSYGELVLEGTFRIQRAKNERTLFLFDKLLLITKKRDDTFTYKAHILCGNLML VEVIPKEPLSFSVFHYKNPKLQHTVQAKSQQDKRLWVLHLKRLILENHAAKIPAKAKQAILEMDAIHHPGFCYSPEGGTKALFGSKEGSA PYRLRRKSEPSSRSHKVLKTSETAQDIQKVSREEGSPQLSSARPSPAQRNSQPSSSTMISVLRAGGALRNIWTDHQIRQALFPSRRSPQE NEDDEDDYQMFVPSFSSSDLNSTRLCEDSTSSRPCSWHMGQMESTETSSSGHRIVRRASSAGESNTCPPEIGTSDRTRELQNSPKTEGQE EMTPFGSSIELTIDDIDHVYDNISYEDLKLMVAKREEAESTPSKSARDSVRPKSTPELAFTKRQAGHSKGSLYAQTDGTLSGGEASSQST HELQAVEENIYDTIGLPDPPSLGFKCSSLKRAKRSTFLGLEADFVCCDSLRPFVSQDSLQLSEDEAPYHQATPDHGYLSLLYDSPSGNLS MPHKPVSDKLSEEVDEIWNDLENYIKKNEDKARDRLLAAFPVSKDDVPDRLHAESTPELSRDVGRSVSTLSLPESQALLTPVKSRAGRAS RANCPFEEDLISKEGSFMSLNRLSLASEMPLMDNPYDLANSGLSQTDPENPDLGMEATDKTKSRVFMMARQYSQKIKKANQLLKVKSLEL EQPPASQHQKSMHKDLAAILEEKKQGGPAIGARIAEYSQLYDQIVFRESPLKIQKDGWASPQESSLLRSVSPSQVHHGSGDWLLHSTYSN GELADFCLPPEQDLRSRYPTFEINTKSTPRQLSAACSVPSLQTSDPLPGSVQRCSVVVSQPNKENWCQDHLYNSLGRKGISAKSQPYHRS QSSSSVLINKSMDSINYPSDVGKQQLLSLHRSSRCESHQDLLPDIADSHQQGTEKLSDLTLQDSQKVVVVNRNLPLNAQIATQNYFSNFK ETDGDEDDYVEIKSEEDESELELSHNRRRKSDSKFVDADFSDNVCSGNTLHSLNSPRTPKKPVNSKLGLSPYLTPYNDSDKLNDYLWRGP -------------------------------------------------------------- >6413_6413_23_ARID1B-PLEKHG1_ARID1B_chr6_157256710_ENST00000367148_PLEKHG1_chr6_151089774_ENST00000358517_length(amino acids)=1914AA_BP=269 MAHNAGAAAAAGTHSAKSGGSEAALKEGGSAAALSSSSSSSAAAAAASSSSSSGPGSAMETGLLPNHKLKTVGEAPAAPPHQQHHHHHHA HHHHHHAHHLHHHHALQQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLS KPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSAS AAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGG SSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPP SQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQ QSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQD MSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDYLDCIRDQTKLPLGTEERSALFGNIQDIYHFNSELLQDLENCENDPVAIAECF VSKSEEFHIYTQYCTNYPRSVAVLTECMRNKILAKFFRERQETLKHSLPLGSYLLKPVQRILKYHLLLHEIENHLDKDTEGYDVVLDAID TMQRVAWHINDMKRKHEHAVRLQEIQSLLTNWKGPDLTSYGELVLEGTFRIQRAKNERTLFLFDKLLLITKKRDDTFTYKAHILCGNLML VEVIPKEPLSFSVFHYKNPKLQHTVQAKSQQDKRLWVLHLKRLILENHAAKIPAKAKQAILEMDAIHHPGFCYSPEGGTKALFGSKEGSA PYRLRRKSEPSSRSHKVLKTSETAQDIQKVSREEGSPQLSSARPSPAQRNSQPSSSTMISVLRAGGALRNIWTDHQIRQALFPSRRSPQE NEDDEDDYQMFVPSFSSSDLNSTRLCEDSTSSRPCSWHMGQMESTETSSSGHRIVRRASSAGESNTCPPEIGTSDRTRELQNSPKTEGQE EMTPFGSSIELTIDDIDHVYDNISYEDLKLMVAKREEAESTPSKSARDSVRPKSTPELAFTKRQAGHSKGSLYAQTDGTLSGGEASSQST HELQAVEENIYDTIGLPDPPSLGFKCSSLKRAKRSTFLGLEADFVCCDSLRPFVSQDSLQLSEDEAPYHQATPDHGYLSLLYDSPSGNLS MPHKPVSDKLSEEVDEIWNDLENYIKKNEDKARDRLLAAFPVSKDDVPDRLHAESTPELSRDVGRSVSTLSLPESQALLTPVKSRAGRAS RANCPFEEDLISKEGSFMSLNRLSLASEMPLMDNPYDLANSGLSQTDPENPDLGMEATDKTKSRVFMMARQYSQKIKKANQLLKVKSLEL EQPPASQHQKSMHKDLAAILEEKKQGGPAIGARIAEYSQLYDQIVFRESPLKIQKDGWASPQESSLLRSVSPSQVHHGSGDWLLHSTYSN GELADFCLPPEQDLRSRYPTFEINTKSTPRQLSAACSVPSLQTSDPLPGSVQRCSVVVSQPNKENWCQDHLYNSLGRKGISAKSQPYHRS QSSSSVLINKSMDSINYPSDVGKQQLLSLHRSSRCESHQDLLPDIADSHQQGTEKLSDLTLQDSQKVVVVNRNLPLNAQIATQNYFSNFK ETDGDEDDYVEIKSEEDESELELSHNRRRKSDSKFVDADFSDNVCSGNTLHSLNSPRTPKKPVNSKLGLSPYLTPYNDSDKLNDYLWRGP -------------------------------------------------------------- >6413_6413_24_ARID1B-PLEKHG1_ARID1B_chr6_157256710_ENST00000367148_PLEKHG1_chr6_151089774_ENST00000367328_length(amino acids)=1914AA_BP=269 MAHNAGAAAAAGTHSAKSGGSEAALKEGGSAAALSSSSSSSAAAAAASSSSSSGPGSAMETGLLPNHKLKTVGEAPAAPPHQQHHHHHHA HHHHHHAHHLHHHHALQQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLS KPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSAS AAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGG SSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPP SQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQ QSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQD MSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDYLDCIRDQTKLPLGTEERSALFGNIQDIYHFNSELLQDLENCENDPVAIAECF VSKSEEFHIYTQYCTNYPRSVAVLTECMRNKILAKFFRERQETLKHSLPLGSYLLKPVQRILKYHLLLHEIENHLDKDTEGYDVVLDAID TMQRVAWHINDMKRKHEHAVRLQEIQSLLTNWKGPDLTSYGELVLEGTFRIQRAKNERTLFLFDKLLLITKKRDDTFTYKAHILCGNLML VEVIPKEPLSFSVFHYKNPKLQHTVQAKSQQDKRLWVLHLKRLILENHAAKIPAKAKQAILEMDAIHHPGFCYSPEGGTKALFGSKEGSA PYRLRRKSEPSSRSHKVLKTSETAQDIQKVSREEGSPQLSSARPSPAQRNSQPSSSTMISVLRAGGALRNIWTDHQIRQALFPSRRSPQE NEDDEDDYQMFVPSFSSSDLNSTRLCEDSTSSRPCSWHMGQMESTETSSSGHRIVRRASSAGESNTCPPEIGTSDRTRELQNSPKTEGQE EMTPFGSSIELTIDDIDHVYDNISYEDLKLMVAKREEAESTPSKSARDSVRPKSTPELAFTKRQAGHSKGSLYAQTDGTLSGGEASSQST HELQAVEENIYDTIGLPDPPSLGFKCSSLKRAKRSTFLGLEADFVCCDSLRPFVSQDSLQLSEDEAPYHQATPDHGYLSLLYDSPSGNLS MPHKPVSDKLSEEVDEIWNDLENYIKKNEDKARDRLLAAFPVSKDDVPDRLHAESTPELSRDVGRSVSTLSLPESQALLTPVKSRAGRAS RANCPFEEDLISKEGSFMSLNRLSLASEMPLMDNPYDLANSGLSQTDPENPDLGMEATDKTKSRVFMMARQYSQKIKKANQLLKVKSLEL EQPPASQHQKSMHKDLAAILEEKKQGGPAIGARIAEYSQLYDQIVFRESPLKIQKDGWASPQESSLLRSVSPSQVHHGSGDWLLHSTYSN GELADFCLPPEQDLRSRYPTFEINTKSTPRQLSAACSVPSLQTSDPLPGSVQRCSVVVSQPNKENWCQDHLYNSLGRKGISAKSQPYHRS QSSSSVLINKSMDSINYPSDVGKQQLLSLHRSSRCESHQDLLPDIADSHQQGTEKLSDLTLQDSQKVVVVNRNLPLNAQIATQNYFSNFK ETDGDEDDYVEIKSEEDESELELSHNRRRKSDSKFVDADFSDNVCSGNTLHSLNSPRTPKKPVNSKLGLSPYLTPYNDSDKLNDYLWRGP -------------------------------------------------------------- |
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Fusion Protein Functional Features |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr6:157256710/chr6:151089774) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| ARID1B | . |
| FUNCTION: Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a postmitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to postmitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth (By similarity). Binds DNA non-specifically (PubMed:14982958, PubMed:15170388). {ECO:0000250|UniProtKB:E9Q4N7, ECO:0000269|PubMed:14982958, ECO:0000269|PubMed:15170388, ECO:0000303|PubMed:12672490, ECO:0000303|PubMed:22952240, ECO:0000303|PubMed:26601204}. | FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - Retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | ARID1B | chr6:157256709 | chr6:151089773 | ENST00000346085 | + | 5 | 20 | 107_131 | 679.0 | 2250.0 | Compositional bias | Note=Gln-rich |
| Hgene | ARID1B | chr6:157256709 | chr6:151089773 | ENST00000346085 | + | 5 | 20 | 114_131 | 679.0 | 2250.0 | Compositional bias | Note=Poly-Gln |
| Hgene | ARID1B | chr6:157256709 | chr6:151089773 | ENST00000346085 | + | 5 | 20 | 141_401 | 679.0 | 2250.0 | Compositional bias | Note=Gly-rich |
| Hgene | ARID1B | chr6:157256709 | chr6:151089773 | ENST00000346085 | + | 5 | 20 | 2_47 | 679.0 | 2250.0 | Compositional bias | Note=Ala-rich |
| Hgene | ARID1B | chr6:157256709 | chr6:151089773 | ENST00000346085 | + | 5 | 20 | 329_493 | 679.0 | 2250.0 | Compositional bias | Note=Ala-rich |
| Hgene | ARID1B | chr6:157256709 | chr6:151089773 | ENST00000346085 | + | 5 | 20 | 35_57 | 679.0 | 2250.0 | Compositional bias | Note=Ser-rich |
| Hgene | ARID1B | chr6:157256709 | chr6:151089773 | ENST00000346085 | + | 5 | 20 | 574_633 | 679.0 | 2250.0 | Compositional bias | Note=Gln-rich |
| Hgene | ARID1B | chr6:157256709 | chr6:151089773 | ENST00000346085 | + | 5 | 20 | 81_104 | 679.0 | 2250.0 | Compositional bias | Note=His-rich |
| Hgene | ARID1B | chr6:157256709 | chr6:151089773 | ENST00000350026 | + | 4 | 19 | 107_131 | 666.0 | 2237.0 | Compositional bias | Note=Gln-rich |
| Hgene | ARID1B | chr6:157256709 | chr6:151089773 | ENST00000350026 | + | 4 | 19 | 114_131 | 666.0 | 2237.0 | Compositional bias | Note=Poly-Gln |
| Hgene | ARID1B | chr6:157256709 | chr6:151089773 | ENST00000350026 | + | 4 | 19 | 141_401 | 666.0 | 2237.0 | Compositional bias | Note=Gly-rich |
| Hgene | ARID1B | chr6:157256709 | chr6:151089773 | ENST00000350026 | + | 4 | 19 | 2_47 | 666.0 | 2237.0 | Compositional bias | Note=Ala-rich |
| Hgene | ARID1B | chr6:157256709 | chr6:151089773 | ENST00000350026 | + | 4 | 19 | 329_493 | 666.0 | 2237.0 | Compositional bias | Note=Ala-rich |
| Hgene | ARID1B | chr6:157256709 | chr6:151089773 | ENST00000350026 | + | 4 | 19 | 35_57 | 666.0 | 2237.0 | Compositional bias | Note=Ser-rich |
| Hgene | ARID1B | chr6:157256709 | chr6:151089773 | ENST00000350026 | + | 4 | 19 | 574_633 | 666.0 | 2237.0 | Compositional bias | Note=Gln-rich |
| Hgene | ARID1B | chr6:157256709 | chr6:151089773 | ENST00000350026 | + | 4 | 19 | 81_104 | 666.0 | 2237.0 | Compositional bias | Note=His-rich |
| Hgene | ARID1B | chr6:157256709 | chr6:151089773 | ENST00000367148 | + | 4 | 20 | 107_131 | 666.0 | 2290.0 | Compositional bias | Note=Gln-rich |
| Hgene | ARID1B | chr6:157256709 | chr6:151089773 | ENST00000367148 | + | 4 | 20 | 114_131 | 666.0 | 2290.0 | Compositional bias | Note=Poly-Gln |
| Hgene | ARID1B | chr6:157256709 | chr6:151089773 | ENST00000367148 | + | 4 | 20 | 141_401 | 666.0 | 2290.0 | Compositional bias | Note=Gly-rich |
| Hgene | ARID1B | chr6:157256709 | chr6:151089773 | ENST00000367148 | + | 4 | 20 | 2_47 | 666.0 | 2290.0 | Compositional bias | Note=Ala-rich |
| Hgene | ARID1B | chr6:157256709 | chr6:151089773 | ENST00000367148 | + | 4 | 20 | 329_493 | 666.0 | 2290.0 | Compositional bias | Note=Ala-rich |
| Hgene | ARID1B | chr6:157256709 | chr6:151089773 | ENST00000367148 | + | 4 | 20 | 35_57 | 666.0 | 2290.0 | Compositional bias | Note=Ser-rich |
| Hgene | ARID1B | chr6:157256709 | chr6:151089773 | ENST00000367148 | + | 4 | 20 | 574_633 | 666.0 | 2290.0 | Compositional bias | Note=Gln-rich |
| Hgene | ARID1B | chr6:157256709 | chr6:151089773 | ENST00000367148 | + | 4 | 20 | 81_104 | 666.0 | 2290.0 | Compositional bias | Note=His-rich |
| Hgene | ARID1B | chr6:157256710 | chr6:151089773 | ENST00000346085 | + | 5 | 20 | 107_131 | 679.0 | 2250.0 | Compositional bias | Note=Gln-rich |
| Hgene | ARID1B | chr6:157256710 | chr6:151089773 | ENST00000346085 | + | 5 | 20 | 114_131 | 679.0 | 2250.0 | Compositional bias | Note=Poly-Gln |
| Hgene | ARID1B | chr6:157256710 | chr6:151089773 | ENST00000346085 | + | 5 | 20 | 141_401 | 679.0 | 2250.0 | Compositional bias | Note=Gly-rich |
| Hgene | ARID1B | chr6:157256710 | chr6:151089773 | ENST00000346085 | + | 5 | 20 | 2_47 | 679.0 | 2250.0 | Compositional bias | Note=Ala-rich |
| Hgene | ARID1B | chr6:157256710 | chr6:151089773 | ENST00000346085 | + | 5 | 20 | 329_493 | 679.0 | 2250.0 | Compositional bias | Note=Ala-rich |
| Hgene | ARID1B | chr6:157256710 | chr6:151089773 | ENST00000346085 | + | 5 | 20 | 35_57 | 679.0 | 2250.0 | Compositional bias | Note=Ser-rich |
| Hgene | ARID1B | chr6:157256710 | chr6:151089773 | ENST00000346085 | + | 5 | 20 | 574_633 | 679.0 | 2250.0 | Compositional bias | Note=Gln-rich |
| Hgene | ARID1B | chr6:157256710 | chr6:151089773 | ENST00000346085 | + | 5 | 20 | 81_104 | 679.0 | 2250.0 | Compositional bias | Note=His-rich |
| Hgene | ARID1B | chr6:157256710 | chr6:151089773 | ENST00000350026 | + | 4 | 19 | 107_131 | 666.0 | 2237.0 | Compositional bias | Note=Gln-rich |
| Hgene | ARID1B | chr6:157256710 | chr6:151089773 | ENST00000350026 | + | 4 | 19 | 114_131 | 666.0 | 2237.0 | Compositional bias | Note=Poly-Gln |
| Hgene | ARID1B | chr6:157256710 | chr6:151089773 | ENST00000350026 | + | 4 | 19 | 141_401 | 666.0 | 2237.0 | Compositional bias | Note=Gly-rich |
| Hgene | ARID1B | chr6:157256710 | chr6:151089773 | ENST00000350026 | + | 4 | 19 | 2_47 | 666.0 | 2237.0 | Compositional bias | Note=Ala-rich |
| Hgene | ARID1B | chr6:157256710 | chr6:151089773 | ENST00000350026 | + | 4 | 19 | 329_493 | 666.0 | 2237.0 | Compositional bias | Note=Ala-rich |
| Hgene | ARID1B | chr6:157256710 | chr6:151089773 | ENST00000350026 | + | 4 | 19 | 35_57 | 666.0 | 2237.0 | Compositional bias | Note=Ser-rich |
| Hgene | ARID1B | chr6:157256710 | chr6:151089773 | ENST00000350026 | + | 4 | 19 | 574_633 | 666.0 | 2237.0 | Compositional bias | Note=Gln-rich |
| Hgene | ARID1B | chr6:157256710 | chr6:151089773 | ENST00000350026 | + | 4 | 19 | 81_104 | 666.0 | 2237.0 | Compositional bias | Note=His-rich |
| Hgene | ARID1B | chr6:157256710 | chr6:151089773 | ENST00000367148 | + | 4 | 20 | 107_131 | 666.0 | 2290.0 | Compositional bias | Note=Gln-rich |
| Hgene | ARID1B | chr6:157256710 | chr6:151089773 | ENST00000367148 | + | 4 | 20 | 114_131 | 666.0 | 2290.0 | Compositional bias | Note=Poly-Gln |
| Hgene | ARID1B | chr6:157256710 | chr6:151089773 | ENST00000367148 | + | 4 | 20 | 141_401 | 666.0 | 2290.0 | Compositional bias | Note=Gly-rich |
| Hgene | ARID1B | chr6:157256710 | chr6:151089773 | ENST00000367148 | + | 4 | 20 | 2_47 | 666.0 | 2290.0 | Compositional bias | Note=Ala-rich |
| Hgene | ARID1B | chr6:157256710 | chr6:151089773 | ENST00000367148 | + | 4 | 20 | 329_493 | 666.0 | 2290.0 | Compositional bias | Note=Ala-rich |
| Hgene | ARID1B | chr6:157256710 | chr6:151089773 | ENST00000367148 | + | 4 | 20 | 35_57 | 666.0 | 2290.0 | Compositional bias | Note=Ser-rich |
| Hgene | ARID1B | chr6:157256710 | chr6:151089773 | ENST00000367148 | + | 4 | 20 | 574_633 | 666.0 | 2290.0 | Compositional bias | Note=Gln-rich |
| Hgene | ARID1B | chr6:157256710 | chr6:151089773 | ENST00000367148 | + | 4 | 20 | 81_104 | 666.0 | 2290.0 | Compositional bias | Note=His-rich |
| Hgene | ARID1B | chr6:157256710 | chr6:151089774 | ENST00000346085 | + | 5 | 20 | 107_131 | 679.0 | 2250.0 | Compositional bias | Note=Gln-rich |
| Hgene | ARID1B | chr6:157256710 | chr6:151089774 | ENST00000346085 | + | 5 | 20 | 114_131 | 679.0 | 2250.0 | Compositional bias | Note=Poly-Gln |
| Hgene | ARID1B | chr6:157256710 | chr6:151089774 | ENST00000346085 | + | 5 | 20 | 141_401 | 679.0 | 2250.0 | Compositional bias | Note=Gly-rich |
| Hgene | ARID1B | chr6:157256710 | chr6:151089774 | ENST00000346085 | + | 5 | 20 | 2_47 | 679.0 | 2250.0 | Compositional bias | Note=Ala-rich |
| Hgene | ARID1B | chr6:157256710 | chr6:151089774 | ENST00000346085 | + | 5 | 20 | 329_493 | 679.0 | 2250.0 | Compositional bias | Note=Ala-rich |
| Hgene | ARID1B | chr6:157256710 | chr6:151089774 | ENST00000346085 | + | 5 | 20 | 35_57 | 679.0 | 2250.0 | Compositional bias | Note=Ser-rich |
| Hgene | ARID1B | chr6:157256710 | chr6:151089774 | ENST00000346085 | + | 5 | 20 | 574_633 | 679.0 | 2250.0 | Compositional bias | Note=Gln-rich |
| Hgene | ARID1B | chr6:157256710 | chr6:151089774 | ENST00000346085 | + | 5 | 20 | 81_104 | 679.0 | 2250.0 | Compositional bias | Note=His-rich |
| Hgene | ARID1B | chr6:157256710 | chr6:151089774 | ENST00000350026 | + | 4 | 19 | 107_131 | 666.0 | 2237.0 | Compositional bias | Note=Gln-rich |
| Hgene | ARID1B | chr6:157256710 | chr6:151089774 | ENST00000350026 | + | 4 | 19 | 114_131 | 666.0 | 2237.0 | Compositional bias | Note=Poly-Gln |
| Hgene | ARID1B | chr6:157256710 | chr6:151089774 | ENST00000350026 | + | 4 | 19 | 141_401 | 666.0 | 2237.0 | Compositional bias | Note=Gly-rich |
| Hgene | ARID1B | chr6:157256710 | chr6:151089774 | ENST00000350026 | + | 4 | 19 | 2_47 | 666.0 | 2237.0 | Compositional bias | Note=Ala-rich |
| Hgene | ARID1B | chr6:157256710 | chr6:151089774 | ENST00000350026 | + | 4 | 19 | 329_493 | 666.0 | 2237.0 | Compositional bias | Note=Ala-rich |
| Hgene | ARID1B | chr6:157256710 | chr6:151089774 | ENST00000350026 | + | 4 | 19 | 35_57 | 666.0 | 2237.0 | Compositional bias | Note=Ser-rich |
| Hgene | ARID1B | chr6:157256710 | chr6:151089774 | ENST00000350026 | + | 4 | 19 | 574_633 | 666.0 | 2237.0 | Compositional bias | Note=Gln-rich |
| Hgene | ARID1B | chr6:157256710 | chr6:151089774 | ENST00000350026 | + | 4 | 19 | 81_104 | 666.0 | 2237.0 | Compositional bias | Note=His-rich |
| Hgene | ARID1B | chr6:157256710 | chr6:151089774 | ENST00000367148 | + | 4 | 20 | 107_131 | 666.0 | 2290.0 | Compositional bias | Note=Gln-rich |
| Hgene | ARID1B | chr6:157256710 | chr6:151089774 | ENST00000367148 | + | 4 | 20 | 114_131 | 666.0 | 2290.0 | Compositional bias | Note=Poly-Gln |
| Hgene | ARID1B | chr6:157256710 | chr6:151089774 | ENST00000367148 | + | 4 | 20 | 141_401 | 666.0 | 2290.0 | Compositional bias | Note=Gly-rich |
| Hgene | ARID1B | chr6:157256710 | chr6:151089774 | ENST00000367148 | + | 4 | 20 | 2_47 | 666.0 | 2290.0 | Compositional bias | Note=Ala-rich |
| Hgene | ARID1B | chr6:157256710 | chr6:151089774 | ENST00000367148 | + | 4 | 20 | 329_493 | 666.0 | 2290.0 | Compositional bias | Note=Ala-rich |
| Hgene | ARID1B | chr6:157256710 | chr6:151089774 | ENST00000367148 | + | 4 | 20 | 35_57 | 666.0 | 2290.0 | Compositional bias | Note=Ser-rich |
| Hgene | ARID1B | chr6:157256710 | chr6:151089774 | ENST00000367148 | + | 4 | 20 | 574_633 | 666.0 | 2290.0 | Compositional bias | Note=Gln-rich |
| Hgene | ARID1B | chr6:157256710 | chr6:151089774 | ENST00000367148 | + | 4 | 20 | 81_104 | 666.0 | 2290.0 | Compositional bias | Note=His-rich |
| Hgene | ARID1B | chr6:157256709 | chr6:151089773 | ENST00000346085 | + | 5 | 20 | 419_423 | 679.0 | 2250.0 | Motif | Note=LXXLL |
| Hgene | ARID1B | chr6:157256709 | chr6:151089773 | ENST00000350026 | + | 4 | 19 | 419_423 | 666.0 | 2237.0 | Motif | Note=LXXLL |
| Hgene | ARID1B | chr6:157256709 | chr6:151089773 | ENST00000367148 | + | 4 | 20 | 419_423 | 666.0 | 2290.0 | Motif | Note=LXXLL |
| Hgene | ARID1B | chr6:157256710 | chr6:151089773 | ENST00000346085 | + | 5 | 20 | 419_423 | 679.0 | 2250.0 | Motif | Note=LXXLL |
| Hgene | ARID1B | chr6:157256710 | chr6:151089773 | ENST00000350026 | + | 4 | 19 | 419_423 | 666.0 | 2237.0 | Motif | Note=LXXLL |
| Hgene | ARID1B | chr6:157256710 | chr6:151089773 | ENST00000367148 | + | 4 | 20 | 419_423 | 666.0 | 2290.0 | Motif | Note=LXXLL |
| Hgene | ARID1B | chr6:157256710 | chr6:151089774 | ENST00000346085 | + | 5 | 20 | 419_423 | 679.0 | 2250.0 | Motif | Note=LXXLL |
| Hgene | ARID1B | chr6:157256710 | chr6:151089774 | ENST00000350026 | + | 4 | 19 | 419_423 | 666.0 | 2237.0 | Motif | Note=LXXLL |
| Hgene | ARID1B | chr6:157256710 | chr6:151089774 | ENST00000367148 | + | 4 | 20 | 419_423 | 666.0 | 2290.0 | Motif | Note=LXXLL |
| Tgene | PLEKHG1 | chr6:157256709 | chr6:151089773 | ENST00000358517 | 1 | 16 | 317_416 | 137.0 | 1386.0 | Domain | PH | |
| Tgene | PLEKHG1 | chr6:157256709 | chr6:151089773 | ENST00000367328 | 2 | 17 | 317_416 | 137.0 | 1386.0 | Domain | PH | |
| Tgene | PLEKHG1 | chr6:157256710 | chr6:151089773 | ENST00000358517 | 1 | 16 | 317_416 | 137.0 | 1386.0 | Domain | PH | |
| Tgene | PLEKHG1 | chr6:157256710 | chr6:151089773 | ENST00000367328 | 2 | 17 | 317_416 | 137.0 | 1386.0 | Domain | PH | |
| Tgene | PLEKHG1 | chr6:157256710 | chr6:151089774 | ENST00000358517 | 1 | 16 | 317_416 | 137.0 | 1386.0 | Domain | PH | |
| Tgene | PLEKHG1 | chr6:157256710 | chr6:151089774 | ENST00000367328 | 2 | 17 | 317_416 | 137.0 | 1386.0 | Domain | PH |
| - Not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | ARID1B | chr6:157256709 | chr6:151089773 | ENST00000346085 | + | 5 | 20 | 1034_1037 | 679.0 | 2250.0 | Compositional bias | Note=Poly-Ser |
| Hgene | ARID1B | chr6:157256709 | chr6:151089773 | ENST00000346085 | + | 5 | 20 | 1441_1444 | 679.0 | 2250.0 | Compositional bias | Note=Poly-Ser |
| Hgene | ARID1B | chr6:157256709 | chr6:151089773 | ENST00000346085 | + | 5 | 20 | 1459_1597 | 679.0 | 2250.0 | Compositional bias | Note=Pro-rich |
| Hgene | ARID1B | chr6:157256709 | chr6:151089773 | ENST00000346085 | + | 5 | 20 | 1833_1836 | 679.0 | 2250.0 | Compositional bias | Note=Poly-Pro |
| Hgene | ARID1B | chr6:157256709 | chr6:151089773 | ENST00000346085 | + | 5 | 20 | 684_771 | 679.0 | 2250.0 | Compositional bias | Note=Ser-rich |
| Hgene | ARID1B | chr6:157256709 | chr6:151089773 | ENST00000346085 | + | 5 | 20 | 932_935 | 679.0 | 2250.0 | Compositional bias | Note=Poly-Ala |
| Hgene | ARID1B | chr6:157256709 | chr6:151089773 | ENST00000350026 | + | 4 | 19 | 1034_1037 | 666.0 | 2237.0 | Compositional bias | Note=Poly-Ser |
| Hgene | ARID1B | chr6:157256709 | chr6:151089773 | ENST00000350026 | + | 4 | 19 | 1441_1444 | 666.0 | 2237.0 | Compositional bias | Note=Poly-Ser |
| Hgene | ARID1B | chr6:157256709 | chr6:151089773 | ENST00000350026 | + | 4 | 19 | 1459_1597 | 666.0 | 2237.0 | Compositional bias | Note=Pro-rich |
| Hgene | ARID1B | chr6:157256709 | chr6:151089773 | ENST00000350026 | + | 4 | 19 | 1833_1836 | 666.0 | 2237.0 | Compositional bias | Note=Poly-Pro |
| Hgene | ARID1B | chr6:157256709 | chr6:151089773 | ENST00000350026 | + | 4 | 19 | 684_771 | 666.0 | 2237.0 | Compositional bias | Note=Ser-rich |
| Hgene | ARID1B | chr6:157256709 | chr6:151089773 | ENST00000350026 | + | 4 | 19 | 932_935 | 666.0 | 2237.0 | Compositional bias | Note=Poly-Ala |
| Hgene | ARID1B | chr6:157256709 | chr6:151089773 | ENST00000367148 | + | 4 | 20 | 1034_1037 | 666.0 | 2290.0 | Compositional bias | Note=Poly-Ser |
| Hgene | ARID1B | chr6:157256709 | chr6:151089773 | ENST00000367148 | + | 4 | 20 | 1441_1444 | 666.0 | 2290.0 | Compositional bias | Note=Poly-Ser |
| Hgene | ARID1B | chr6:157256709 | chr6:151089773 | ENST00000367148 | + | 4 | 20 | 1459_1597 | 666.0 | 2290.0 | Compositional bias | Note=Pro-rich |
| Hgene | ARID1B | chr6:157256709 | chr6:151089773 | ENST00000367148 | + | 4 | 20 | 1833_1836 | 666.0 | 2290.0 | Compositional bias | Note=Poly-Pro |
| Hgene | ARID1B | chr6:157256709 | chr6:151089773 | ENST00000367148 | + | 4 | 20 | 684_771 | 666.0 | 2290.0 | Compositional bias | Note=Ser-rich |
| Hgene | ARID1B | chr6:157256709 | chr6:151089773 | ENST00000367148 | + | 4 | 20 | 932_935 | 666.0 | 2290.0 | Compositional bias | Note=Poly-Ala |
| Hgene | ARID1B | chr6:157256710 | chr6:151089773 | ENST00000346085 | + | 5 | 20 | 1034_1037 | 679.0 | 2250.0 | Compositional bias | Note=Poly-Ser |
| Hgene | ARID1B | chr6:157256710 | chr6:151089773 | ENST00000346085 | + | 5 | 20 | 1441_1444 | 679.0 | 2250.0 | Compositional bias | Note=Poly-Ser |
| Hgene | ARID1B | chr6:157256710 | chr6:151089773 | ENST00000346085 | + | 5 | 20 | 1459_1597 | 679.0 | 2250.0 | Compositional bias | Note=Pro-rich |
| Hgene | ARID1B | chr6:157256710 | chr6:151089773 | ENST00000346085 | + | 5 | 20 | 1833_1836 | 679.0 | 2250.0 | Compositional bias | Note=Poly-Pro |
| Hgene | ARID1B | chr6:157256710 | chr6:151089773 | ENST00000346085 | + | 5 | 20 | 684_771 | 679.0 | 2250.0 | Compositional bias | Note=Ser-rich |
| Hgene | ARID1B | chr6:157256710 | chr6:151089773 | ENST00000346085 | + | 5 | 20 | 932_935 | 679.0 | 2250.0 | Compositional bias | Note=Poly-Ala |
| Hgene | ARID1B | chr6:157256710 | chr6:151089773 | ENST00000350026 | + | 4 | 19 | 1034_1037 | 666.0 | 2237.0 | Compositional bias | Note=Poly-Ser |
| Hgene | ARID1B | chr6:157256710 | chr6:151089773 | ENST00000350026 | + | 4 | 19 | 1441_1444 | 666.0 | 2237.0 | Compositional bias | Note=Poly-Ser |
| Hgene | ARID1B | chr6:157256710 | chr6:151089773 | ENST00000350026 | + | 4 | 19 | 1459_1597 | 666.0 | 2237.0 | Compositional bias | Note=Pro-rich |
| Hgene | ARID1B | chr6:157256710 | chr6:151089773 | ENST00000350026 | + | 4 | 19 | 1833_1836 | 666.0 | 2237.0 | Compositional bias | Note=Poly-Pro |
| Hgene | ARID1B | chr6:157256710 | chr6:151089773 | ENST00000350026 | + | 4 | 19 | 684_771 | 666.0 | 2237.0 | Compositional bias | Note=Ser-rich |
| Hgene | ARID1B | chr6:157256710 | chr6:151089773 | ENST00000350026 | + | 4 | 19 | 932_935 | 666.0 | 2237.0 | Compositional bias | Note=Poly-Ala |
| Hgene | ARID1B | chr6:157256710 | chr6:151089773 | ENST00000367148 | + | 4 | 20 | 1034_1037 | 666.0 | 2290.0 | Compositional bias | Note=Poly-Ser |
| Hgene | ARID1B | chr6:157256710 | chr6:151089773 | ENST00000367148 | + | 4 | 20 | 1441_1444 | 666.0 | 2290.0 | Compositional bias | Note=Poly-Ser |
| Hgene | ARID1B | chr6:157256710 | chr6:151089773 | ENST00000367148 | + | 4 | 20 | 1459_1597 | 666.0 | 2290.0 | Compositional bias | Note=Pro-rich |
| Hgene | ARID1B | chr6:157256710 | chr6:151089773 | ENST00000367148 | + | 4 | 20 | 1833_1836 | 666.0 | 2290.0 | Compositional bias | Note=Poly-Pro |
| Hgene | ARID1B | chr6:157256710 | chr6:151089773 | ENST00000367148 | + | 4 | 20 | 684_771 | 666.0 | 2290.0 | Compositional bias | Note=Ser-rich |
| Hgene | ARID1B | chr6:157256710 | chr6:151089773 | ENST00000367148 | + | 4 | 20 | 932_935 | 666.0 | 2290.0 | Compositional bias | Note=Poly-Ala |
| Hgene | ARID1B | chr6:157256710 | chr6:151089774 | ENST00000346085 | + | 5 | 20 | 1034_1037 | 679.0 | 2250.0 | Compositional bias | Note=Poly-Ser |
| Hgene | ARID1B | chr6:157256710 | chr6:151089774 | ENST00000346085 | + | 5 | 20 | 1441_1444 | 679.0 | 2250.0 | Compositional bias | Note=Poly-Ser |
| Hgene | ARID1B | chr6:157256710 | chr6:151089774 | ENST00000346085 | + | 5 | 20 | 1459_1597 | 679.0 | 2250.0 | Compositional bias | Note=Pro-rich |
| Hgene | ARID1B | chr6:157256710 | chr6:151089774 | ENST00000346085 | + | 5 | 20 | 1833_1836 | 679.0 | 2250.0 | Compositional bias | Note=Poly-Pro |
| Hgene | ARID1B | chr6:157256710 | chr6:151089774 | ENST00000346085 | + | 5 | 20 | 684_771 | 679.0 | 2250.0 | Compositional bias | Note=Ser-rich |
| Hgene | ARID1B | chr6:157256710 | chr6:151089774 | ENST00000346085 | + | 5 | 20 | 932_935 | 679.0 | 2250.0 | Compositional bias | Note=Poly-Ala |
| Hgene | ARID1B | chr6:157256710 | chr6:151089774 | ENST00000350026 | + | 4 | 19 | 1034_1037 | 666.0 | 2237.0 | Compositional bias | Note=Poly-Ser |
| Hgene | ARID1B | chr6:157256710 | chr6:151089774 | ENST00000350026 | + | 4 | 19 | 1441_1444 | 666.0 | 2237.0 | Compositional bias | Note=Poly-Ser |
| Hgene | ARID1B | chr6:157256710 | chr6:151089774 | ENST00000350026 | + | 4 | 19 | 1459_1597 | 666.0 | 2237.0 | Compositional bias | Note=Pro-rich |
| Hgene | ARID1B | chr6:157256710 | chr6:151089774 | ENST00000350026 | + | 4 | 19 | 1833_1836 | 666.0 | 2237.0 | Compositional bias | Note=Poly-Pro |
| Hgene | ARID1B | chr6:157256710 | chr6:151089774 | ENST00000350026 | + | 4 | 19 | 684_771 | 666.0 | 2237.0 | Compositional bias | Note=Ser-rich |
| Hgene | ARID1B | chr6:157256710 | chr6:151089774 | ENST00000350026 | + | 4 | 19 | 932_935 | 666.0 | 2237.0 | Compositional bias | Note=Poly-Ala |
| Hgene | ARID1B | chr6:157256710 | chr6:151089774 | ENST00000367148 | + | 4 | 20 | 1034_1037 | 666.0 | 2290.0 | Compositional bias | Note=Poly-Ser |
| Hgene | ARID1B | chr6:157256710 | chr6:151089774 | ENST00000367148 | + | 4 | 20 | 1441_1444 | 666.0 | 2290.0 | Compositional bias | Note=Poly-Ser |
| Hgene | ARID1B | chr6:157256710 | chr6:151089774 | ENST00000367148 | + | 4 | 20 | 1459_1597 | 666.0 | 2290.0 | Compositional bias | Note=Pro-rich |
| Hgene | ARID1B | chr6:157256710 | chr6:151089774 | ENST00000367148 | + | 4 | 20 | 1833_1836 | 666.0 | 2290.0 | Compositional bias | Note=Poly-Pro |
| Hgene | ARID1B | chr6:157256710 | chr6:151089774 | ENST00000367148 | + | 4 | 20 | 684_771 | 666.0 | 2290.0 | Compositional bias | Note=Ser-rich |
| Hgene | ARID1B | chr6:157256710 | chr6:151089774 | ENST00000367148 | + | 4 | 20 | 932_935 | 666.0 | 2290.0 | Compositional bias | Note=Poly-Ala |
| Hgene | ARID1B | chr6:157256709 | chr6:151089773 | ENST00000346085 | + | 5 | 20 | 1053_1144 | 679.0 | 2250.0 | Domain | ARID |
| Hgene | ARID1B | chr6:157256709 | chr6:151089773 | ENST00000350026 | + | 4 | 19 | 1053_1144 | 666.0 | 2237.0 | Domain | ARID |
| Hgene | ARID1B | chr6:157256709 | chr6:151089773 | ENST00000367148 | + | 4 | 20 | 1053_1144 | 666.0 | 2290.0 | Domain | ARID |
| Hgene | ARID1B | chr6:157256710 | chr6:151089773 | ENST00000346085 | + | 5 | 20 | 1053_1144 | 679.0 | 2250.0 | Domain | ARID |
| Hgene | ARID1B | chr6:157256710 | chr6:151089773 | ENST00000350026 | + | 4 | 19 | 1053_1144 | 666.0 | 2237.0 | Domain | ARID |
| Hgene | ARID1B | chr6:157256710 | chr6:151089773 | ENST00000367148 | + | 4 | 20 | 1053_1144 | 666.0 | 2290.0 | Domain | ARID |
| Hgene | ARID1B | chr6:157256710 | chr6:151089774 | ENST00000346085 | + | 5 | 20 | 1053_1144 | 679.0 | 2250.0 | Domain | ARID |
| Hgene | ARID1B | chr6:157256710 | chr6:151089774 | ENST00000350026 | + | 4 | 19 | 1053_1144 | 666.0 | 2237.0 | Domain | ARID |
| Hgene | ARID1B | chr6:157256710 | chr6:151089774 | ENST00000367148 | + | 4 | 20 | 1053_1144 | 666.0 | 2290.0 | Domain | ARID |
| Hgene | ARID1B | chr6:157256709 | chr6:151089773 | ENST00000346085 | + | 5 | 20 | 1358_1377 | 679.0 | 2250.0 | Motif | Nuclear localization signal |
| Hgene | ARID1B | chr6:157256709 | chr6:151089773 | ENST00000346085 | + | 5 | 20 | 2036_2040 | 679.0 | 2250.0 | Motif | Note=LXXLL |
| Hgene | ARID1B | chr6:157256709 | chr6:151089773 | ENST00000350026 | + | 4 | 19 | 1358_1377 | 666.0 | 2237.0 | Motif | Nuclear localization signal |
| Hgene | ARID1B | chr6:157256709 | chr6:151089773 | ENST00000350026 | + | 4 | 19 | 2036_2040 | 666.0 | 2237.0 | Motif | Note=LXXLL |
| Hgene | ARID1B | chr6:157256709 | chr6:151089773 | ENST00000367148 | + | 4 | 20 | 1358_1377 | 666.0 | 2290.0 | Motif | Nuclear localization signal |
| Hgene | ARID1B | chr6:157256709 | chr6:151089773 | ENST00000367148 | + | 4 | 20 | 2036_2040 | 666.0 | 2290.0 | Motif | Note=LXXLL |
| Hgene | ARID1B | chr6:157256710 | chr6:151089773 | ENST00000346085 | + | 5 | 20 | 1358_1377 | 679.0 | 2250.0 | Motif | Nuclear localization signal |
| Hgene | ARID1B | chr6:157256710 | chr6:151089773 | ENST00000346085 | + | 5 | 20 | 2036_2040 | 679.0 | 2250.0 | Motif | Note=LXXLL |
| Hgene | ARID1B | chr6:157256710 | chr6:151089773 | ENST00000350026 | + | 4 | 19 | 1358_1377 | 666.0 | 2237.0 | Motif | Nuclear localization signal |
| Hgene | ARID1B | chr6:157256710 | chr6:151089773 | ENST00000350026 | + | 4 | 19 | 2036_2040 | 666.0 | 2237.0 | Motif | Note=LXXLL |
| Hgene | ARID1B | chr6:157256710 | chr6:151089773 | ENST00000367148 | + | 4 | 20 | 1358_1377 | 666.0 | 2290.0 | Motif | Nuclear localization signal |
| Hgene | ARID1B | chr6:157256710 | chr6:151089773 | ENST00000367148 | + | 4 | 20 | 2036_2040 | 666.0 | 2290.0 | Motif | Note=LXXLL |
| Hgene | ARID1B | chr6:157256710 | chr6:151089774 | ENST00000346085 | + | 5 | 20 | 1358_1377 | 679.0 | 2250.0 | Motif | Nuclear localization signal |
| Hgene | ARID1B | chr6:157256710 | chr6:151089774 | ENST00000346085 | + | 5 | 20 | 2036_2040 | 679.0 | 2250.0 | Motif | Note=LXXLL |
| Hgene | ARID1B | chr6:157256710 | chr6:151089774 | ENST00000350026 | + | 4 | 19 | 1358_1377 | 666.0 | 2237.0 | Motif | Nuclear localization signal |
| Hgene | ARID1B | chr6:157256710 | chr6:151089774 | ENST00000350026 | + | 4 | 19 | 2036_2040 | 666.0 | 2237.0 | Motif | Note=LXXLL |
| Hgene | ARID1B | chr6:157256710 | chr6:151089774 | ENST00000367148 | + | 4 | 20 | 1358_1377 | 666.0 | 2290.0 | Motif | Nuclear localization signal |
| Hgene | ARID1B | chr6:157256710 | chr6:151089774 | ENST00000367148 | + | 4 | 20 | 2036_2040 | 666.0 | 2290.0 | Motif | Note=LXXLL |
| Tgene | PLEKHG1 | chr6:157256709 | chr6:151089773 | ENST00000358517 | 1 | 16 | 113_293 | 137.0 | 1386.0 | Domain | DH | |
| Tgene | PLEKHG1 | chr6:157256709 | chr6:151089773 | ENST00000367328 | 2 | 17 | 113_293 | 137.0 | 1386.0 | Domain | DH | |
| Tgene | PLEKHG1 | chr6:157256710 | chr6:151089773 | ENST00000358517 | 1 | 16 | 113_293 | 137.0 | 1386.0 | Domain | DH | |
| Tgene | PLEKHG1 | chr6:157256710 | chr6:151089773 | ENST00000367328 | 2 | 17 | 113_293 | 137.0 | 1386.0 | Domain | DH | |
| Tgene | PLEKHG1 | chr6:157256710 | chr6:151089774 | ENST00000358517 | 1 | 16 | 113_293 | 137.0 | 1386.0 | Domain | DH | |
| Tgene | PLEKHG1 | chr6:157256710 | chr6:151089774 | ENST00000367328 | 2 | 17 | 113_293 | 137.0 | 1386.0 | Domain | DH |
Top |
Fusion Protein-Protein Interaction |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type from validated records (BIOGRID-3.4.160) |
| Gene | PPI interactors |
| Protein-protein interactors based on sequence similarity (STRING) |
| Gene | STRING network |
| ARID1B | |
| PLEKHG1 |
| - Retained interactions in fusion protein (protein functional feature from UniProt). |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost interactions due to fusion (protein functional feature from UniProt). |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs to ARID1B-PLEKHG1 |
| Drugs used for this fusion-positive patient. (Manual curation of PubMed, 04-30-2022 + MyCancerGenome) |
| Hgene | Tgene | Drug | Source | PMID |
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Related Diseases to ARID1B-PLEKHG1 |
| Diseases that have this fusion gene. (Manual curation of PubMed, 04-30-2022 + MyCancerGenome) |
| Hgene | Tgene | Disease | Source | PMID |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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