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Center for Computational Systems Medicine level1
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Fusion Gene Summary

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Fusion Gene Sample Information

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Fusion ORF Analysis

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Fusion Amino Acid Sequences

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Fusion Protein Functional Features

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Fusion Protein-Protein Interaction

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Related drugs with this fusion protein

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Related disease with this fusion protein

Fusion Protein:PLEC-KSR1

Fusion Protein Summary

check button Fusion gene summary
Fusion partner gene informationFusion gene name: PLEC-KSR1
FusionPDB ID: 66133
FusionGDB2.0 ID: 66133
HgeneTgene
Gene symbol

PLEC

KSR1

Gene ID

5339

8844

Gene nameplectinkinase suppressor of ras 1
SynonymsEBS1|EBSMD|EBSND|EBSO|EBSOG|EBSPA|HD1|LGMD2Q|LGMDR17|PCN|PLEC1|PLEC1b|PLTNKSR|RSU2
Cytomap

8q24.3

17q11.2

Type of geneprotein-codingprotein-coding
Descriptionplectinhemidesmosomal protein 1plectin 1, intermediate filament binding protein 500kDakinase suppressor of Ras 1
Modification date2020031320200327
UniProtAcc

PLEC

Q8IVT5

Ensembl transtripts involved in fusion geneENST idsENST00000436759, ENST00000527096, 
ENST00000322810, ENST00000345136, 
ENST00000354589, ENST00000354958, 
ENST00000356346, ENST00000357649, 
ENST00000398774, 		ENST00000268763, 
ENST00000398988, ENST00000578981, 
ENST00000581975, ENST00000582410, 
ENST00000319524, ENST00000509603, 
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)* DoF score26 X 19 X 12=592813 X 9 X 7=819
# samples 2612
** MAII scorelog2(26/5928*10)=-4.51096191927738
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(12/819*10)=-2.77082904603249
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context (manual curation of fusion genes in FusionPDB)

PubMed: PLEC [Title/Abstract] AND KSR1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)PLEC(145049345)-KSR1(25877594), # samples:1
Anticipated loss of major functional domain due to fusion event.PLEC-KSR1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
PLEC-KSR1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
PLEC-KSR1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
PLEC-KSR1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgenePLEC

GO:0031581

hemidesmosome assembly

12482924

TgeneKSR1

GO:0000185

activation of MAPKKK activity

29433126


check buttonFusion gene breakpoints across PLEC (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across KSR1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure


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Fusion Gene Sample Information

check buttonFusion gene information from FusionGDB2.0.
check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-AC-A5XU-01APLECchr8

145049345

-KSR1chr17

25877594

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Fusion ORF Analysis


check buttonFusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000436759PLECchr8145049345-ENST00000509603KSR1chr1725877594+2631231542630859
ENST00000436759PLECchr8145049345-ENST00000319524KSR1chr1725877594+3071231542771905
ENST00000527096PLECchr8145049345-ENST00000509603KSR1chr1725877594+2593193162592859
ENST00000527096PLECchr8145049345-ENST00000319524KSR1chr1725877594+3033193162733905

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000436759ENST00000509603PLECchr8145049345-KSR1chr1725877594+0.62147010.37852988
ENST00000436759ENST00000319524PLECchr8145049345-KSR1chr1725877594+0.0171913490.98280865
ENST00000527096ENST00000509603PLECchr8145049345-KSR1chr1725877594+0.644882260.35511777
ENST00000527096ENST00000319524PLECchr8145049345-KSR1chr1725877594+0.0165399160.9834601

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Fusion Amino Acid Sequences


check button For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

>66133_66133_1_PLEC-KSR1_PLEC_chr8_145049345_ENST00000436759_KSR1_chr17_25877594_ENST00000319524_length(amino acids)=905AA_BP=58
MRSGQSLKMSPMEAVARPALGTHCPGTLGKRSGAGAAGVALGATGVSWTQLSGRSFASQAKLVRYICKQRQCKLSVAPGERTPELNSYPR
FSDWLYTFNVRPEVVQEIPRDLTLDALLEMNEAKVKETLRRCGASGDECGRLQYALTCLRKVTGLGGEHKEDSSWSSLDARRESGSGPST
DTLSAASLPWPPGSSQLGRAGNSAQGPRSISVSALPASDSPTPSFSEGLSDTCIPLHASGRLTPRALHSFITPPTTPQLRRHTKLKPPRT
PPPPSRKVFQLLPSFPTLTRSKSHESQLGNRIDDVSSMRFDLSHGSPQMVRRDIGLSVTHRFSTKSWLSQVCHVCQKSMIFGVKCKHCRL
KCHNKCTKEAPACRISFLPLTRLRRTESVPSDINNPVDRAAEPHFGTLPKALTKKEHPPAMNHLDSSSNPSSTTSSTPSSPAPFPTSSNP
SSATTPPNPSPGQRDSRFNFPAAYFIHHRQQFIFPVPSAGHCWKCLLIAESLKENAFNISAFAHAAPLPEAADGTRLDDQPKADVLEAHE
AEAEEPEAGKSEAEDDEDEVDDLPSSRRPWRGPISRKASQTSVYLQEWDIPFEQVELGEPIGQGRWGRVHRGRWHGEVAIRLLEMDGHNQ
DHLKLFKKEVMNYRQTRHENVVLFMGACMNPPHLAIITSFCKGRTLHSFVRDPKTSLDINKTRQIAQEIIKGMGYLHAKGIVHKDLKSKN
VFYDNGKVVITDFGLFGISGVVREGRRENQLKLSHDWLCYLAPEIVREMTPGKDEDQLPFSKAADVYAFGTVWYELQARDWPLKNQAAEA
SIWQIGSGEGMKRVLTSVSLGKEVSEILSACWAFDLQERPSFSLLMDMLEKLPKLNRRLSHPGHFWKSADINSSKVVPRFERFGLGVLES

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>66133_66133_2_PLEC-KSR1_PLEC_chr8_145049345_ENST00000436759_KSR1_chr17_25877594_ENST00000509603_length(amino acids)=859AA_BP=58
MRSGQSLKMSPMEAVARPALGTHCPGTLGKRSGAGAAGVALGATGVSWTQLSGRSFASQAKLVRYICKQRQCKLSVAPGERTPELNSYPR
FSDWLYTFNVRPEVVQEIPRDLTLDALLEMNEAKVKETLRRCGASGDECGRLQYALTCLRKVTGLGGEHKEDSSWSSLDARRESGSGPST
DTLSAASLPWPPGSSQLGRAGNSAQGPRSISVSALPASDSPTPSFSEGLSDTCIPLHASGRLTPRALHSFITPPTTPQLRRHTKLKPPRT
PPPPSRKVFQLLPSFPTLTRSKSHESQLGNRIDDVSSMRFDLSHGSPQMVRRDIGLSVTHRFSTKSWLSQVCHVCQKSMIFGVKCKHCRL
KCHNKCTKEAPACRISFLPLTRLRRTESVPSDINNPVDRAAEPHFGTLPKALTKKEHPPAMNHLDSSSNPSSTTSSTPSSPAPFPTSSNP
SSATTPPNPSPGQRDSRFNFPAAYFIHHRQQFIFPDISAFAHAAPLPEAADGTRLDDQPKADVLEAHEAEAEEPEAGKSEAEDDEDEVDD
LPSSRRPWRGPISRKASQTSVYLQEWDIPFEQVELGEPIGQGRWGRVHRGRWHGEVAIRLLEMDGHNQDHLKLFKKEVMNYRQTRHENVV
LFMGACMNPPHLAIITSFCKGRTLHSFVRDPKTSLDINKTRQIAQEIIKGMGYLHAKGIVHKDLKSKNVFYDNGKVVITDFGLFGISGVV
REGRRENQLKLSHDWLCYLAPEIVREMTPGKDEDQLPFSKAADVYAFGTVWYELQARDWPLKNQAAEASIWQIGSGEGMKRVLTSVSLGK

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>66133_66133_3_PLEC-KSR1_PLEC_chr8_145049345_ENST00000527096_KSR1_chr17_25877594_ENST00000319524_length(amino acids)=905AA_BP=58
MRSGQSLKMSPMEAVARPALGTHCPGTLGKRSGAGAAGVALGATGVSWTQLSGRSFASQAKLVRYICKQRQCKLSVAPGERTPELNSYPR
FSDWLYTFNVRPEVVQEIPRDLTLDALLEMNEAKVKETLRRCGASGDECGRLQYALTCLRKVTGLGGEHKEDSSWSSLDARRESGSGPST
DTLSAASLPWPPGSSQLGRAGNSAQGPRSISVSALPASDSPTPSFSEGLSDTCIPLHASGRLTPRALHSFITPPTTPQLRRHTKLKPPRT
PPPPSRKVFQLLPSFPTLTRSKSHESQLGNRIDDVSSMRFDLSHGSPQMVRRDIGLSVTHRFSTKSWLSQVCHVCQKSMIFGVKCKHCRL
KCHNKCTKEAPACRISFLPLTRLRRTESVPSDINNPVDRAAEPHFGTLPKALTKKEHPPAMNHLDSSSNPSSTTSSTPSSPAPFPTSSNP
SSATTPPNPSPGQRDSRFNFPAAYFIHHRQQFIFPVPSAGHCWKCLLIAESLKENAFNISAFAHAAPLPEAADGTRLDDQPKADVLEAHE
AEAEEPEAGKSEAEDDEDEVDDLPSSRRPWRGPISRKASQTSVYLQEWDIPFEQVELGEPIGQGRWGRVHRGRWHGEVAIRLLEMDGHNQ
DHLKLFKKEVMNYRQTRHENVVLFMGACMNPPHLAIITSFCKGRTLHSFVRDPKTSLDINKTRQIAQEIIKGMGYLHAKGIVHKDLKSKN
VFYDNGKVVITDFGLFGISGVVREGRRENQLKLSHDWLCYLAPEIVREMTPGKDEDQLPFSKAADVYAFGTVWYELQARDWPLKNQAAEA
SIWQIGSGEGMKRVLTSVSLGKEVSEILSACWAFDLQERPSFSLLMDMLEKLPKLNRRLSHPGHFWKSADINSSKVVPRFERFGLGVLES

--------------------------------------------------------------

>66133_66133_4_PLEC-KSR1_PLEC_chr8_145049345_ENST00000527096_KSR1_chr17_25877594_ENST00000509603_length(amino acids)=859AA_BP=58
MRSGQSLKMSPMEAVARPALGTHCPGTLGKRSGAGAAGVALGATGVSWTQLSGRSFASQAKLVRYICKQRQCKLSVAPGERTPELNSYPR
FSDWLYTFNVRPEVVQEIPRDLTLDALLEMNEAKVKETLRRCGASGDECGRLQYALTCLRKVTGLGGEHKEDSSWSSLDARRESGSGPST
DTLSAASLPWPPGSSQLGRAGNSAQGPRSISVSALPASDSPTPSFSEGLSDTCIPLHASGRLTPRALHSFITPPTTPQLRRHTKLKPPRT
PPPPSRKVFQLLPSFPTLTRSKSHESQLGNRIDDVSSMRFDLSHGSPQMVRRDIGLSVTHRFSTKSWLSQVCHVCQKSMIFGVKCKHCRL
KCHNKCTKEAPACRISFLPLTRLRRTESVPSDINNPVDRAAEPHFGTLPKALTKKEHPPAMNHLDSSSNPSSTTSSTPSSPAPFPTSSNP
SSATTPPNPSPGQRDSRFNFPAAYFIHHRQQFIFPDISAFAHAAPLPEAADGTRLDDQPKADVLEAHEAEAEEPEAGKSEAEDDEDEVDD
LPSSRRPWRGPISRKASQTSVYLQEWDIPFEQVELGEPIGQGRWGRVHRGRWHGEVAIRLLEMDGHNQDHLKLFKKEVMNYRQTRHENVV
LFMGACMNPPHLAIITSFCKGRTLHSFVRDPKTSLDINKTRQIAQEIIKGMGYLHAKGIVHKDLKSKNVFYDNGKVVITDFGLFGISGVV
REGRRENQLKLSHDWLCYLAPEIVREMTPGKDEDQLPFSKAADVYAFGTVWYELQARDWPLKNQAAEASIWQIGSGEGMKRVLTSVSLGK

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Fusion Protein Functional Features


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr8:145049345/chr17:25877594)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
PLEC

PLEC

KSR1

Q8IVT5

4684FUNCTION: Part of a multiprotein signaling complex which promotes phosphorylation of Raf family members and activation of downstream MAP kinases (By similarity). Independently of its kinase activity, acts as MAP2K1/MEK1 and MAP2K2/MEK2-dependent allosteric activator of BRAF; upon binding to MAP2K1/MEK1 or MAP2K2/MEK2, dimerizes with BRAF and promotes BRAF-mediated phosphorylation of MAP2K1/MEK1 and/or MAP2K2/MEK2 (PubMed:29433126). Promotes activation of MAPK1 and/or MAPK3, both in response to EGF and to cAMP (By similarity). Its kinase activity is unsure (By similarity). Some protein kinase activity has been detected in vitro, however the physiological relevance of this activity is unknown (By similarity). {ECO:0000250|UniProtKB:Q61097, ECO:0000269|PubMed:29433126}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

* Minus value of BPloci means that the break pointn is located before the CDS.
- Retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneKSR1chr8:145049345chr17:25877594ENST0000026876312217_210787.0Compositional biasNote=Poly-Gly
TgeneKSR1chr8:145049345chr17:25877594ENST00000268763122289_2920787.0Compositional biasNote=Poly-Pro
TgeneKSR1chr8:145049345chr17:25877594ENST00000268763122613_8830787.0DomainProtein kinase
TgeneKSR1chr8:145049345chr17:25877594ENST00000268763122619_6270787.0Nucleotide bindingATP
TgeneKSR1chr8:145049345chr17:25877594ENST000002687631221_1720787.0RegionMediates association with membranes
TgeneKSR1chr8:145049345chr17:25877594ENST00000268763122347_3910787.0Zinc fingerPhorbol-ester/DAG-type

- Not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePLECchr8:145049345chr17:25877594ENST00000322810-1321469_275604685.0Coiled coilOntology_term=ECO:0000255
HgenePLECchr8:145049345chr17:25877594ENST00000345136-1321469_275604548.0Coiled coilOntology_term=ECO:0000255
HgenePLECchr8:145049345chr17:25877594ENST00000354589-1321469_275604548.0Coiled coilOntology_term=ECO:0000255
HgenePLECchr8:145049345chr17:25877594ENST00000354958-1321469_275604526.0Coiled coilOntology_term=ECO:0000255
HgenePLECchr8:145049345chr17:25877594ENST00000356346-1321469_275604534.0Coiled coilOntology_term=ECO:0000255
HgenePLECchr8:145049345chr17:25877594ENST00000357649-1321469_275604552.0Coiled coilOntology_term=ECO:0000255
HgenePLECchr8:145049345chr17:25877594ENST00000398774-1321469_275604516.0Coiled coilOntology_term=ECO:0000255
HgenePLECchr8:145049345chr17:25877594ENST00000436759-2331469_275664.333333333333334575.0Coiled coilOntology_term=ECO:0000255
HgenePLECchr8:145049345chr17:25877594ENST00000527096-1321469_275664.333333333333334571.0Coiled coilOntology_term=ECO:0000255
HgenePLECchr8:145049345chr17:25877594ENST00000322810-132179_28204685.0DomainCalponin-homology (CH) 1
HgenePLECchr8:145049345chr17:25877594ENST00000322810-132295_40004685.0DomainCalponin-homology (CH) 2
HgenePLECchr8:145049345chr17:25877594ENST00000322810-132941_99804685.0DomainSH3
HgenePLECchr8:145049345chr17:25877594ENST00000345136-132179_28204548.0DomainCalponin-homology (CH) 1
HgenePLECchr8:145049345chr17:25877594ENST00000345136-132295_40004548.0DomainCalponin-homology (CH) 2
HgenePLECchr8:145049345chr17:25877594ENST00000345136-132941_99804548.0DomainSH3
HgenePLECchr8:145049345chr17:25877594ENST00000354589-132179_28204548.0DomainCalponin-homology (CH) 1
HgenePLECchr8:145049345chr17:25877594ENST00000354589-132295_40004548.0DomainCalponin-homology (CH) 2
HgenePLECchr8:145049345chr17:25877594ENST00000354589-132941_99804548.0DomainSH3
HgenePLECchr8:145049345chr17:25877594ENST00000354958-132179_28204526.0DomainCalponin-homology (CH) 1
HgenePLECchr8:145049345chr17:25877594ENST00000354958-132295_40004526.0DomainCalponin-homology (CH) 2
HgenePLECchr8:145049345chr17:25877594ENST00000354958-132941_99804526.0DomainSH3
HgenePLECchr8:145049345chr17:25877594ENST00000356346-132179_28204534.0DomainCalponin-homology (CH) 1
HgenePLECchr8:145049345chr17:25877594ENST00000356346-132295_40004534.0DomainCalponin-homology (CH) 2
HgenePLECchr8:145049345chr17:25877594ENST00000356346-132941_99804534.0DomainSH3
HgenePLECchr8:145049345chr17:25877594ENST00000357649-132179_28204552.0DomainCalponin-homology (CH) 1
HgenePLECchr8:145049345chr17:25877594ENST00000357649-132295_40004552.0DomainCalponin-homology (CH) 2
HgenePLECchr8:145049345chr17:25877594ENST00000357649-132941_99804552.0DomainSH3
HgenePLECchr8:145049345chr17:25877594ENST00000398774-132179_28204516.0DomainCalponin-homology (CH) 1
HgenePLECchr8:145049345chr17:25877594ENST00000398774-132295_40004516.0DomainCalponin-homology (CH) 2
HgenePLECchr8:145049345chr17:25877594ENST00000398774-132941_99804516.0DomainSH3
HgenePLECchr8:145049345chr17:25877594ENST00000436759-233179_28264.333333333333334575.0DomainCalponin-homology (CH) 1
HgenePLECchr8:145049345chr17:25877594ENST00000436759-233295_40064.333333333333334575.0DomainCalponin-homology (CH) 2
HgenePLECchr8:145049345chr17:25877594ENST00000436759-233941_99864.333333333333334575.0DomainSH3
HgenePLECchr8:145049345chr17:25877594ENST00000527096-132179_28264.333333333333334571.0DomainCalponin-homology (CH) 1
HgenePLECchr8:145049345chr17:25877594ENST00000527096-132295_40064.333333333333334571.0DomainCalponin-homology (CH) 2
HgenePLECchr8:145049345chr17:25877594ENST00000527096-132941_99864.333333333333334571.0DomainSH3
HgenePLECchr8:145049345chr17:25877594ENST00000322810-1321471_275504685.0RegionNote=Central fibrous rod domain
HgenePLECchr8:145049345chr17:25877594ENST00000322810-132175_40004685.0RegionNote=Actin-binding
HgenePLECchr8:145049345chr17:25877594ENST00000322810-1321_147004685.0RegionNote=Globular 1
HgenePLECchr8:145049345chr17:25877594ENST00000322810-1322756_468404685.0RegionNote=Globular 2
HgenePLECchr8:145049345chr17:25877594ENST00000322810-1324250_430004685.0RegionBinding to intermediate filaments
HgenePLECchr8:145049345chr17:25877594ENST00000322810-1324625_464004685.0RegionNote=4 X 4 AA tandem repeats of G-S-R-X
HgenePLECchr8:145049345chr17:25877594ENST00000345136-1321471_275504548.0RegionNote=Central fibrous rod domain
HgenePLECchr8:145049345chr17:25877594ENST00000345136-132175_40004548.0RegionNote=Actin-binding
HgenePLECchr8:145049345chr17:25877594ENST00000345136-1321_147004548.0RegionNote=Globular 1
HgenePLECchr8:145049345chr17:25877594ENST00000345136-1322756_468404548.0RegionNote=Globular 2
HgenePLECchr8:145049345chr17:25877594ENST00000345136-1324250_430004548.0RegionBinding to intermediate filaments
HgenePLECchr8:145049345chr17:25877594ENST00000345136-1324625_464004548.0RegionNote=4 X 4 AA tandem repeats of G-S-R-X
HgenePLECchr8:145049345chr17:25877594ENST00000354589-1321471_275504548.0RegionNote=Central fibrous rod domain
HgenePLECchr8:145049345chr17:25877594ENST00000354589-132175_40004548.0RegionNote=Actin-binding
HgenePLECchr8:145049345chr17:25877594ENST00000354589-1321_147004548.0RegionNote=Globular 1
HgenePLECchr8:145049345chr17:25877594ENST00000354589-1322756_468404548.0RegionNote=Globular 2
HgenePLECchr8:145049345chr17:25877594ENST00000354589-1324250_430004548.0RegionBinding to intermediate filaments
HgenePLECchr8:145049345chr17:25877594ENST00000354589-1324625_464004548.0RegionNote=4 X 4 AA tandem repeats of G-S-R-X
HgenePLECchr8:145049345chr17:25877594ENST00000354958-1321471_275504526.0RegionNote=Central fibrous rod domain
HgenePLECchr8:145049345chr17:25877594ENST00000354958-132175_40004526.0RegionNote=Actin-binding
HgenePLECchr8:145049345chr17:25877594ENST00000354958-1321_147004526.0RegionNote=Globular 1
HgenePLECchr8:145049345chr17:25877594ENST00000354958-1322756_468404526.0RegionNote=Globular 2
HgenePLECchr8:145049345chr17:25877594ENST00000354958-1324250_430004526.0RegionBinding to intermediate filaments
HgenePLECchr8:145049345chr17:25877594ENST00000354958-1324625_464004526.0RegionNote=4 X 4 AA tandem repeats of G-S-R-X
HgenePLECchr8:145049345chr17:25877594ENST00000356346-1321471_275504534.0RegionNote=Central fibrous rod domain
HgenePLECchr8:145049345chr17:25877594ENST00000356346-132175_40004534.0RegionNote=Actin-binding
HgenePLECchr8:145049345chr17:25877594ENST00000356346-1321_147004534.0RegionNote=Globular 1
HgenePLECchr8:145049345chr17:25877594ENST00000356346-1322756_468404534.0RegionNote=Globular 2
HgenePLECchr8:145049345chr17:25877594ENST00000356346-1324250_430004534.0RegionBinding to intermediate filaments
HgenePLECchr8:145049345chr17:25877594ENST00000356346-1324625_464004534.0RegionNote=4 X 4 AA tandem repeats of G-S-R-X
HgenePLECchr8:145049345chr17:25877594ENST00000357649-1321471_275504552.0RegionNote=Central fibrous rod domain
HgenePLECchr8:145049345chr17:25877594ENST00000357649-132175_40004552.0RegionNote=Actin-binding
HgenePLECchr8:145049345chr17:25877594ENST00000357649-1321_147004552.0RegionNote=Globular 1
HgenePLECchr8:145049345chr17:25877594ENST00000357649-1322756_468404552.0RegionNote=Globular 2
HgenePLECchr8:145049345chr17:25877594ENST00000357649-1324250_430004552.0RegionBinding to intermediate filaments
HgenePLECchr8:145049345chr17:25877594ENST00000357649-1324625_464004552.0RegionNote=4 X 4 AA tandem repeats of G-S-R-X
HgenePLECchr8:145049345chr17:25877594ENST00000398774-1321471_275504516.0RegionNote=Central fibrous rod domain
HgenePLECchr8:145049345chr17:25877594ENST00000398774-132175_40004516.0RegionNote=Actin-binding
HgenePLECchr8:145049345chr17:25877594ENST00000398774-1321_147004516.0RegionNote=Globular 1
HgenePLECchr8:145049345chr17:25877594ENST00000398774-1322756_468404516.0RegionNote=Globular 2
HgenePLECchr8:145049345chr17:25877594ENST00000398774-1324250_430004516.0RegionBinding to intermediate filaments
HgenePLECchr8:145049345chr17:25877594ENST00000398774-1324625_464004516.0RegionNote=4 X 4 AA tandem repeats of G-S-R-X
HgenePLECchr8:145049345chr17:25877594ENST00000436759-2331471_275564.333333333333334575.0RegionNote=Central fibrous rod domain
HgenePLECchr8:145049345chr17:25877594ENST00000436759-233175_40064.333333333333334575.0RegionNote=Actin-binding
HgenePLECchr8:145049345chr17:25877594ENST00000436759-2331_147064.333333333333334575.0RegionNote=Globular 1
HgenePLECchr8:145049345chr17:25877594ENST00000436759-2332756_468464.333333333333334575.0RegionNote=Globular 2
HgenePLECchr8:145049345chr17:25877594ENST00000436759-2334250_430064.333333333333334575.0RegionBinding to intermediate filaments
HgenePLECchr8:145049345chr17:25877594ENST00000436759-2334625_464064.333333333333334575.0RegionNote=4 X 4 AA tandem repeats of G-S-R-X
HgenePLECchr8:145049345chr17:25877594ENST00000527096-1321471_275564.333333333333334571.0RegionNote=Central fibrous rod domain
HgenePLECchr8:145049345chr17:25877594ENST00000527096-132175_40064.333333333333334571.0RegionNote=Actin-binding
HgenePLECchr8:145049345chr17:25877594ENST00000527096-1321_147064.333333333333334571.0RegionNote=Globular 1
HgenePLECchr8:145049345chr17:25877594ENST00000527096-1322756_468464.333333333333334571.0RegionNote=Globular 2
HgenePLECchr8:145049345chr17:25877594ENST00000527096-1324250_430064.333333333333334571.0RegionBinding to intermediate filaments
HgenePLECchr8:145049345chr17:25877594ENST00000527096-1324625_464064.333333333333334571.0RegionNote=4 X 4 AA tandem repeats of G-S-R-X
HgenePLECchr8:145049345chr17:25877594ENST00000322810-1321315_141504685.0RepeatNote=Spectrin 4
HgenePLECchr8:145049345chr17:25877594ENST00000322810-1322826_286304685.0RepeatNote=Plectin 1
HgenePLECchr8:145049345chr17:25877594ENST00000322810-1322864_290104685.0RepeatNote=Plectin 2
HgenePLECchr8:145049345chr17:25877594ENST00000322810-1322902_293904685.0RepeatNote=Plectin 3
HgenePLECchr8:145049345chr17:25877594ENST00000322810-1322940_297704685.0RepeatNote=Plectin 4
HgenePLECchr8:145049345chr17:25877594ENST00000322810-1322981_301504685.0RepeatNote=Plectin 5
HgenePLECchr8:145049345chr17:25877594ENST00000322810-1323116_315304685.0RepeatNote=Plectin 6
HgenePLECchr8:145049345chr17:25877594ENST00000322810-1323154_319104685.0RepeatNote=Plectin 7
HgenePLECchr8:145049345chr17:25877594ENST00000322810-1323192_322904685.0RepeatNote=Plectin 8
HgenePLECchr8:145049345chr17:25877594ENST00000322810-1323230_326704685.0RepeatNote=Plectin 9
HgenePLECchr8:145049345chr17:25877594ENST00000322810-1323268_330504685.0RepeatNote=Plectin 10
HgenePLECchr8:145049345chr17:25877594ENST00000322810-1323306_334304685.0RepeatNote=Plectin 11
HgenePLECchr8:145049345chr17:25877594ENST00000322810-1323485_352204685.0RepeatNote=Plectin 12
HgenePLECchr8:145049345chr17:25877594ENST00000322810-1323523_356004685.0RepeatNote=Plectin 13
HgenePLECchr8:145049345chr17:25877594ENST00000322810-1323561_359804685.0RepeatNote=Plectin 14
HgenePLECchr8:145049345chr17:25877594ENST00000322810-1323599_363604685.0RepeatNote=Plectin 15
HgenePLECchr8:145049345chr17:25877594ENST00000322810-1323640_367404685.0RepeatNote=Plectin 16
HgenePLECchr8:145049345chr17:25877594ENST00000322810-1323820_385704685.0RepeatNote=Plectin 17
HgenePLECchr8:145049345chr17:25877594ENST00000322810-1323858_389504685.0RepeatNote=Plectin 18
HgenePLECchr8:145049345chr17:25877594ENST00000322810-1323896_393304685.0RepeatNote=Plectin 19
HgenePLECchr8:145049345chr17:25877594ENST00000322810-1323934_397104685.0RepeatNote=Plectin 20
HgenePLECchr8:145049345chr17:25877594ENST00000322810-1323975_400804685.0RepeatNote=Plectin 21
HgenePLECchr8:145049345chr17:25877594ENST00000322810-1324063_410004685.0RepeatNote=Plectin 22
HgenePLECchr8:145049345chr17:25877594ENST00000322810-1324101_413804685.0RepeatNote=Plectin 23
HgenePLECchr8:145049345chr17:25877594ENST00000322810-1324139_417604685.0RepeatNote=Plectin 24
HgenePLECchr8:145049345chr17:25877594ENST00000322810-1324177_421404685.0RepeatNote=Plectin 25
HgenePLECchr8:145049345chr17:25877594ENST00000322810-1324218_425204685.0RepeatNote=Plectin 26
HgenePLECchr8:145049345chr17:25877594ENST00000322810-1324265_430504685.0RepeatNote=Plectin 27
HgenePLECchr8:145049345chr17:25877594ENST00000322810-1324319_435604685.0RepeatNote=Plectin 28
HgenePLECchr8:145049345chr17:25877594ENST00000322810-1324408_444504685.0RepeatNote=Plectin 29
HgenePLECchr8:145049345chr17:25877594ENST00000322810-1324446_448304685.0RepeatNote=Plectin 30
HgenePLECchr8:145049345chr17:25877594ENST00000322810-1324484_452104685.0RepeatNote=Plectin 31
HgenePLECchr8:145049345chr17:25877594ENST00000322810-1324522_455904685.0RepeatNote=Plectin 32
HgenePLECchr8:145049345chr17:25877594ENST00000322810-1324560_459704685.0RepeatNote=Plectin 33
HgenePLECchr8:145049345chr17:25877594ENST00000322810-132645_71004685.0RepeatNote=Spectrin 1
HgenePLECchr8:145049345chr17:25877594ENST00000322810-132740_82404685.0RepeatNote=Spectrin 2
HgenePLECchr8:145049345chr17:25877594ENST00000322810-132837_93004685.0RepeatNote=Spectrin 3
HgenePLECchr8:145049345chr17:25877594ENST00000345136-1321315_141504548.0RepeatNote=Spectrin 4
HgenePLECchr8:145049345chr17:25877594ENST00000345136-1322826_286304548.0RepeatNote=Plectin 1
HgenePLECchr8:145049345chr17:25877594ENST00000345136-1322864_290104548.0RepeatNote=Plectin 2
HgenePLECchr8:145049345chr17:25877594ENST00000345136-1322902_293904548.0RepeatNote=Plectin 3
HgenePLECchr8:145049345chr17:25877594ENST00000345136-1322940_297704548.0RepeatNote=Plectin 4
HgenePLECchr8:145049345chr17:25877594ENST00000345136-1322981_301504548.0RepeatNote=Plectin 5
HgenePLECchr8:145049345chr17:25877594ENST00000345136-1323116_315304548.0RepeatNote=Plectin 6
HgenePLECchr8:145049345chr17:25877594ENST00000345136-1323154_319104548.0RepeatNote=Plectin 7
HgenePLECchr8:145049345chr17:25877594ENST00000345136-1323192_322904548.0RepeatNote=Plectin 8
HgenePLECchr8:145049345chr17:25877594ENST00000345136-1323230_326704548.0RepeatNote=Plectin 9
HgenePLECchr8:145049345chr17:25877594ENST00000345136-1323268_330504548.0RepeatNote=Plectin 10
HgenePLECchr8:145049345chr17:25877594ENST00000345136-1323306_334304548.0RepeatNote=Plectin 11
HgenePLECchr8:145049345chr17:25877594ENST00000345136-1323485_352204548.0RepeatNote=Plectin 12
HgenePLECchr8:145049345chr17:25877594ENST00000345136-1323523_356004548.0RepeatNote=Plectin 13
HgenePLECchr8:145049345chr17:25877594ENST00000345136-1323561_359804548.0RepeatNote=Plectin 14
HgenePLECchr8:145049345chr17:25877594ENST00000345136-1323599_363604548.0RepeatNote=Plectin 15
HgenePLECchr8:145049345chr17:25877594ENST00000345136-1323640_367404548.0RepeatNote=Plectin 16
HgenePLECchr8:145049345chr17:25877594ENST00000345136-1323820_385704548.0RepeatNote=Plectin 17
HgenePLECchr8:145049345chr17:25877594ENST00000345136-1323858_389504548.0RepeatNote=Plectin 18
HgenePLECchr8:145049345chr17:25877594ENST00000345136-1323896_393304548.0RepeatNote=Plectin 19
HgenePLECchr8:145049345chr17:25877594ENST00000345136-1323934_397104548.0RepeatNote=Plectin 20
HgenePLECchr8:145049345chr17:25877594ENST00000345136-1323975_400804548.0RepeatNote=Plectin 21
HgenePLECchr8:145049345chr17:25877594ENST00000345136-1324063_410004548.0RepeatNote=Plectin 22
HgenePLECchr8:145049345chr17:25877594ENST00000345136-1324101_413804548.0RepeatNote=Plectin 23
HgenePLECchr8:145049345chr17:25877594ENST00000345136-1324139_417604548.0RepeatNote=Plectin 24
HgenePLECchr8:145049345chr17:25877594ENST00000345136-1324177_421404548.0RepeatNote=Plectin 25
HgenePLECchr8:145049345chr17:25877594ENST00000345136-1324218_425204548.0RepeatNote=Plectin 26
HgenePLECchr8:145049345chr17:25877594ENST00000345136-1324265_430504548.0RepeatNote=Plectin 27
HgenePLECchr8:145049345chr17:25877594ENST00000345136-1324319_435604548.0RepeatNote=Plectin 28
HgenePLECchr8:145049345chr17:25877594ENST00000345136-1324408_444504548.0RepeatNote=Plectin 29
HgenePLECchr8:145049345chr17:25877594ENST00000345136-1324446_448304548.0RepeatNote=Plectin 30
HgenePLECchr8:145049345chr17:25877594ENST00000345136-1324484_452104548.0RepeatNote=Plectin 31
HgenePLECchr8:145049345chr17:25877594ENST00000345136-1324522_455904548.0RepeatNote=Plectin 32
HgenePLECchr8:145049345chr17:25877594ENST00000345136-1324560_459704548.0RepeatNote=Plectin 33
HgenePLECchr8:145049345chr17:25877594ENST00000345136-132645_71004548.0RepeatNote=Spectrin 1
HgenePLECchr8:145049345chr17:25877594ENST00000345136-132740_82404548.0RepeatNote=Spectrin 2
HgenePLECchr8:145049345chr17:25877594ENST00000345136-132837_93004548.0RepeatNote=Spectrin 3
HgenePLECchr8:145049345chr17:25877594ENST00000354589-1321315_141504548.0RepeatNote=Spectrin 4
HgenePLECchr8:145049345chr17:25877594ENST00000354589-1322826_286304548.0RepeatNote=Plectin 1
HgenePLECchr8:145049345chr17:25877594ENST00000354589-1322864_290104548.0RepeatNote=Plectin 2
HgenePLECchr8:145049345chr17:25877594ENST00000354589-1322902_293904548.0RepeatNote=Plectin 3
HgenePLECchr8:145049345chr17:25877594ENST00000354589-1322940_297704548.0RepeatNote=Plectin 4
HgenePLECchr8:145049345chr17:25877594ENST00000354589-1322981_301504548.0RepeatNote=Plectin 5
HgenePLECchr8:145049345chr17:25877594ENST00000354589-1323116_315304548.0RepeatNote=Plectin 6
HgenePLECchr8:145049345chr17:25877594ENST00000354589-1323154_319104548.0RepeatNote=Plectin 7
HgenePLECchr8:145049345chr17:25877594ENST00000354589-1323192_322904548.0RepeatNote=Plectin 8
HgenePLECchr8:145049345chr17:25877594ENST00000354589-1323230_326704548.0RepeatNote=Plectin 9
HgenePLECchr8:145049345chr17:25877594ENST00000354589-1323268_330504548.0RepeatNote=Plectin 10
HgenePLECchr8:145049345chr17:25877594ENST00000354589-1323306_334304548.0RepeatNote=Plectin 11
HgenePLECchr8:145049345chr17:25877594ENST00000354589-1323485_352204548.0RepeatNote=Plectin 12
HgenePLECchr8:145049345chr17:25877594ENST00000354589-1323523_356004548.0RepeatNote=Plectin 13
HgenePLECchr8:145049345chr17:25877594ENST00000354589-1323561_359804548.0RepeatNote=Plectin 14
HgenePLECchr8:145049345chr17:25877594ENST00000354589-1323599_363604548.0RepeatNote=Plectin 15
HgenePLECchr8:145049345chr17:25877594ENST00000354589-1323640_367404548.0RepeatNote=Plectin 16
HgenePLECchr8:145049345chr17:25877594ENST00000354589-1323820_385704548.0RepeatNote=Plectin 17
HgenePLECchr8:145049345chr17:25877594ENST00000354589-1323858_389504548.0RepeatNote=Plectin 18
HgenePLECchr8:145049345chr17:25877594ENST00000354589-1323896_393304548.0RepeatNote=Plectin 19
HgenePLECchr8:145049345chr17:25877594ENST00000354589-1323934_397104548.0RepeatNote=Plectin 20
HgenePLECchr8:145049345chr17:25877594ENST00000354589-1323975_400804548.0RepeatNote=Plectin 21
HgenePLECchr8:145049345chr17:25877594ENST00000354589-1324063_410004548.0RepeatNote=Plectin 22
HgenePLECchr8:145049345chr17:25877594ENST00000354589-1324101_413804548.0RepeatNote=Plectin 23
HgenePLECchr8:145049345chr17:25877594ENST00000354589-1324139_417604548.0RepeatNote=Plectin 24
HgenePLECchr8:145049345chr17:25877594ENST00000354589-1324177_421404548.0RepeatNote=Plectin 25
HgenePLECchr8:145049345chr17:25877594ENST00000354589-1324218_425204548.0RepeatNote=Plectin 26
HgenePLECchr8:145049345chr17:25877594ENST00000354589-1324265_430504548.0RepeatNote=Plectin 27
HgenePLECchr8:145049345chr17:25877594ENST00000354589-1324319_435604548.0RepeatNote=Plectin 28
HgenePLECchr8:145049345chr17:25877594ENST00000354589-1324408_444504548.0RepeatNote=Plectin 29
HgenePLECchr8:145049345chr17:25877594ENST00000354589-1324446_448304548.0RepeatNote=Plectin 30
HgenePLECchr8:145049345chr17:25877594ENST00000354589-1324484_452104548.0RepeatNote=Plectin 31
HgenePLECchr8:145049345chr17:25877594ENST00000354589-1324522_455904548.0RepeatNote=Plectin 32
HgenePLECchr8:145049345chr17:25877594ENST00000354589-1324560_459704548.0RepeatNote=Plectin 33
HgenePLECchr8:145049345chr17:25877594ENST00000354589-132645_71004548.0RepeatNote=Spectrin 1
HgenePLECchr8:145049345chr17:25877594ENST00000354589-132740_82404548.0RepeatNote=Spectrin 2
HgenePLECchr8:145049345chr17:25877594ENST00000354589-132837_93004548.0RepeatNote=Spectrin 3
HgenePLECchr8:145049345chr17:25877594ENST00000354958-1321315_141504526.0RepeatNote=Spectrin 4
HgenePLECchr8:145049345chr17:25877594ENST00000354958-1322826_286304526.0RepeatNote=Plectin 1
HgenePLECchr8:145049345chr17:25877594ENST00000354958-1322864_290104526.0RepeatNote=Plectin 2
HgenePLECchr8:145049345chr17:25877594ENST00000354958-1322902_293904526.0RepeatNote=Plectin 3
HgenePLECchr8:145049345chr17:25877594ENST00000354958-1322940_297704526.0RepeatNote=Plectin 4
HgenePLECchr8:145049345chr17:25877594ENST00000354958-1322981_301504526.0RepeatNote=Plectin 5
HgenePLECchr8:145049345chr17:25877594ENST00000354958-1323116_315304526.0RepeatNote=Plectin 6
HgenePLECchr8:145049345chr17:25877594ENST00000354958-1323154_319104526.0RepeatNote=Plectin 7
HgenePLECchr8:145049345chr17:25877594ENST00000354958-1323192_322904526.0RepeatNote=Plectin 8
HgenePLECchr8:145049345chr17:25877594ENST00000354958-1323230_326704526.0RepeatNote=Plectin 9
HgenePLECchr8:145049345chr17:25877594ENST00000354958-1323268_330504526.0RepeatNote=Plectin 10
HgenePLECchr8:145049345chr17:25877594ENST00000354958-1323306_334304526.0RepeatNote=Plectin 11
HgenePLECchr8:145049345chr17:25877594ENST00000354958-1323485_352204526.0RepeatNote=Plectin 12
HgenePLECchr8:145049345chr17:25877594ENST00000354958-1323523_356004526.0RepeatNote=Plectin 13
HgenePLECchr8:145049345chr17:25877594ENST00000354958-1323561_359804526.0RepeatNote=Plectin 14
HgenePLECchr8:145049345chr17:25877594ENST00000354958-1323599_363604526.0RepeatNote=Plectin 15
HgenePLECchr8:145049345chr17:25877594ENST00000354958-1323640_367404526.0RepeatNote=Plectin 16
HgenePLECchr8:145049345chr17:25877594ENST00000354958-1323820_385704526.0RepeatNote=Plectin 17
HgenePLECchr8:145049345chr17:25877594ENST00000354958-1323858_389504526.0RepeatNote=Plectin 18
HgenePLECchr8:145049345chr17:25877594ENST00000354958-1323896_393304526.0RepeatNote=Plectin 19
HgenePLECchr8:145049345chr17:25877594ENST00000354958-1323934_397104526.0RepeatNote=Plectin 20
HgenePLECchr8:145049345chr17:25877594ENST00000354958-1323975_400804526.0RepeatNote=Plectin 21
HgenePLECchr8:145049345chr17:25877594ENST00000354958-1324063_410004526.0RepeatNote=Plectin 22
HgenePLECchr8:145049345chr17:25877594ENST00000354958-1324101_413804526.0RepeatNote=Plectin 23
HgenePLECchr8:145049345chr17:25877594ENST00000354958-1324139_417604526.0RepeatNote=Plectin 24
HgenePLECchr8:145049345chr17:25877594ENST00000354958-1324177_421404526.0RepeatNote=Plectin 25
HgenePLECchr8:145049345chr17:25877594ENST00000354958-1324218_425204526.0RepeatNote=Plectin 26
HgenePLECchr8:145049345chr17:25877594ENST00000354958-1324265_430504526.0RepeatNote=Plectin 27
HgenePLECchr8:145049345chr17:25877594ENST00000354958-1324319_435604526.0RepeatNote=Plectin 28
HgenePLECchr8:145049345chr17:25877594ENST00000354958-1324408_444504526.0RepeatNote=Plectin 29
HgenePLECchr8:145049345chr17:25877594ENST00000354958-1324446_448304526.0RepeatNote=Plectin 30
HgenePLECchr8:145049345chr17:25877594ENST00000354958-1324484_452104526.0RepeatNote=Plectin 31
HgenePLECchr8:145049345chr17:25877594ENST00000354958-1324522_455904526.0RepeatNote=Plectin 32
HgenePLECchr8:145049345chr17:25877594ENST00000354958-1324560_459704526.0RepeatNote=Plectin 33
HgenePLECchr8:145049345chr17:25877594ENST00000354958-132645_71004526.0RepeatNote=Spectrin 1
HgenePLECchr8:145049345chr17:25877594ENST00000354958-132740_82404526.0RepeatNote=Spectrin 2
HgenePLECchr8:145049345chr17:25877594ENST00000354958-132837_93004526.0RepeatNote=Spectrin 3
HgenePLECchr8:145049345chr17:25877594ENST00000356346-1321315_141504534.0RepeatNote=Spectrin 4
HgenePLECchr8:145049345chr17:25877594ENST00000356346-1322826_286304534.0RepeatNote=Plectin 1
HgenePLECchr8:145049345chr17:25877594ENST00000356346-1322864_290104534.0RepeatNote=Plectin 2
HgenePLECchr8:145049345chr17:25877594ENST00000356346-1322902_293904534.0RepeatNote=Plectin 3
HgenePLECchr8:145049345chr17:25877594ENST00000356346-1322940_297704534.0RepeatNote=Plectin 4
HgenePLECchr8:145049345chr17:25877594ENST00000356346-1322981_301504534.0RepeatNote=Plectin 5
HgenePLECchr8:145049345chr17:25877594ENST00000356346-1323116_315304534.0RepeatNote=Plectin 6
HgenePLECchr8:145049345chr17:25877594ENST00000356346-1323154_319104534.0RepeatNote=Plectin 7
HgenePLECchr8:145049345chr17:25877594ENST00000356346-1323192_322904534.0RepeatNote=Plectin 8
HgenePLECchr8:145049345chr17:25877594ENST00000356346-1323230_326704534.0RepeatNote=Plectin 9
HgenePLECchr8:145049345chr17:25877594ENST00000356346-1323268_330504534.0RepeatNote=Plectin 10
HgenePLECchr8:145049345chr17:25877594ENST00000356346-1323306_334304534.0RepeatNote=Plectin 11
HgenePLECchr8:145049345chr17:25877594ENST00000356346-1323485_352204534.0RepeatNote=Plectin 12
HgenePLECchr8:145049345chr17:25877594ENST00000356346-1323523_356004534.0RepeatNote=Plectin 13
HgenePLECchr8:145049345chr17:25877594ENST00000356346-1323561_359804534.0RepeatNote=Plectin 14
HgenePLECchr8:145049345chr17:25877594ENST00000356346-1323599_363604534.0RepeatNote=Plectin 15
HgenePLECchr8:145049345chr17:25877594ENST00000356346-1323640_367404534.0RepeatNote=Plectin 16
HgenePLECchr8:145049345chr17:25877594ENST00000356346-1323820_385704534.0RepeatNote=Plectin 17
HgenePLECchr8:145049345chr17:25877594ENST00000356346-1323858_389504534.0RepeatNote=Plectin 18
HgenePLECchr8:145049345chr17:25877594ENST00000356346-1323896_393304534.0RepeatNote=Plectin 19
HgenePLECchr8:145049345chr17:25877594ENST00000356346-1323934_397104534.0RepeatNote=Plectin 20
HgenePLECchr8:145049345chr17:25877594ENST00000356346-1323975_400804534.0RepeatNote=Plectin 21
HgenePLECchr8:145049345chr17:25877594ENST00000356346-1324063_410004534.0RepeatNote=Plectin 22
HgenePLECchr8:145049345chr17:25877594ENST00000356346-1324101_413804534.0RepeatNote=Plectin 23
HgenePLECchr8:145049345chr17:25877594ENST00000356346-1324139_417604534.0RepeatNote=Plectin 24
HgenePLECchr8:145049345chr17:25877594ENST00000356346-1324177_421404534.0RepeatNote=Plectin 25
HgenePLECchr8:145049345chr17:25877594ENST00000356346-1324218_425204534.0RepeatNote=Plectin 26
HgenePLECchr8:145049345chr17:25877594ENST00000356346-1324265_430504534.0RepeatNote=Plectin 27
HgenePLECchr8:145049345chr17:25877594ENST00000356346-1324319_435604534.0RepeatNote=Plectin 28
HgenePLECchr8:145049345chr17:25877594ENST00000356346-1324408_444504534.0RepeatNote=Plectin 29
HgenePLECchr8:145049345chr17:25877594ENST00000356346-1324446_448304534.0RepeatNote=Plectin 30
HgenePLECchr8:145049345chr17:25877594ENST00000356346-1324484_452104534.0RepeatNote=Plectin 31
HgenePLECchr8:145049345chr17:25877594ENST00000356346-1324522_455904534.0RepeatNote=Plectin 32
HgenePLECchr8:145049345chr17:25877594ENST00000356346-1324560_459704534.0RepeatNote=Plectin 33
HgenePLECchr8:145049345chr17:25877594ENST00000356346-132645_71004534.0RepeatNote=Spectrin 1
HgenePLECchr8:145049345chr17:25877594ENST00000356346-132740_82404534.0RepeatNote=Spectrin 2
HgenePLECchr8:145049345chr17:25877594ENST00000356346-132837_93004534.0RepeatNote=Spectrin 3
HgenePLECchr8:145049345chr17:25877594ENST00000357649-1321315_141504552.0RepeatNote=Spectrin 4
HgenePLECchr8:145049345chr17:25877594ENST00000357649-1322826_286304552.0RepeatNote=Plectin 1
HgenePLECchr8:145049345chr17:25877594ENST00000357649-1322864_290104552.0RepeatNote=Plectin 2
HgenePLECchr8:145049345chr17:25877594ENST00000357649-1322902_293904552.0RepeatNote=Plectin 3
HgenePLECchr8:145049345chr17:25877594ENST00000357649-1322940_297704552.0RepeatNote=Plectin 4
HgenePLECchr8:145049345chr17:25877594ENST00000357649-1322981_301504552.0RepeatNote=Plectin 5
HgenePLECchr8:145049345chr17:25877594ENST00000357649-1323116_315304552.0RepeatNote=Plectin 6
HgenePLECchr8:145049345chr17:25877594ENST00000357649-1323154_319104552.0RepeatNote=Plectin 7
HgenePLECchr8:145049345chr17:25877594ENST00000357649-1323192_322904552.0RepeatNote=Plectin 8
HgenePLECchr8:145049345chr17:25877594ENST00000357649-1323230_326704552.0RepeatNote=Plectin 9
HgenePLECchr8:145049345chr17:25877594ENST00000357649-1323268_330504552.0RepeatNote=Plectin 10
HgenePLECchr8:145049345chr17:25877594ENST00000357649-1323306_334304552.0RepeatNote=Plectin 11
HgenePLECchr8:145049345chr17:25877594ENST00000357649-1323485_352204552.0RepeatNote=Plectin 12
HgenePLECchr8:145049345chr17:25877594ENST00000357649-1323523_356004552.0RepeatNote=Plectin 13
HgenePLECchr8:145049345chr17:25877594ENST00000357649-1323561_359804552.0RepeatNote=Plectin 14
HgenePLECchr8:145049345chr17:25877594ENST00000357649-1323599_363604552.0RepeatNote=Plectin 15
HgenePLECchr8:145049345chr17:25877594ENST00000357649-1323640_367404552.0RepeatNote=Plectin 16
HgenePLECchr8:145049345chr17:25877594ENST00000357649-1323820_385704552.0RepeatNote=Plectin 17
HgenePLECchr8:145049345chr17:25877594ENST00000357649-1323858_389504552.0RepeatNote=Plectin 18
HgenePLECchr8:145049345chr17:25877594ENST00000357649-1323896_393304552.0RepeatNote=Plectin 19
HgenePLECchr8:145049345chr17:25877594ENST00000357649-1323934_397104552.0RepeatNote=Plectin 20
HgenePLECchr8:145049345chr17:25877594ENST00000357649-1323975_400804552.0RepeatNote=Plectin 21
HgenePLECchr8:145049345chr17:25877594ENST00000357649-1324063_410004552.0RepeatNote=Plectin 22
HgenePLECchr8:145049345chr17:25877594ENST00000357649-1324101_413804552.0RepeatNote=Plectin 23
HgenePLECchr8:145049345chr17:25877594ENST00000357649-1324139_417604552.0RepeatNote=Plectin 24
HgenePLECchr8:145049345chr17:25877594ENST00000357649-1324177_421404552.0RepeatNote=Plectin 25
HgenePLECchr8:145049345chr17:25877594ENST00000357649-1324218_425204552.0RepeatNote=Plectin 26
HgenePLECchr8:145049345chr17:25877594ENST00000357649-1324265_430504552.0RepeatNote=Plectin 27
HgenePLECchr8:145049345chr17:25877594ENST00000357649-1324319_435604552.0RepeatNote=Plectin 28
HgenePLECchr8:145049345chr17:25877594ENST00000357649-1324408_444504552.0RepeatNote=Plectin 29
HgenePLECchr8:145049345chr17:25877594ENST00000357649-1324446_448304552.0RepeatNote=Plectin 30
HgenePLECchr8:145049345chr17:25877594ENST00000357649-1324484_452104552.0RepeatNote=Plectin 31
HgenePLECchr8:145049345chr17:25877594ENST00000357649-1324522_455904552.0RepeatNote=Plectin 32
HgenePLECchr8:145049345chr17:25877594ENST00000357649-1324560_459704552.0RepeatNote=Plectin 33
HgenePLECchr8:145049345chr17:25877594ENST00000357649-132645_71004552.0RepeatNote=Spectrin 1
HgenePLECchr8:145049345chr17:25877594ENST00000357649-132740_82404552.0RepeatNote=Spectrin 2
HgenePLECchr8:145049345chr17:25877594ENST00000357649-132837_93004552.0RepeatNote=Spectrin 3
HgenePLECchr8:145049345chr17:25877594ENST00000398774-1321315_141504516.0RepeatNote=Spectrin 4
HgenePLECchr8:145049345chr17:25877594ENST00000398774-1322826_286304516.0RepeatNote=Plectin 1
HgenePLECchr8:145049345chr17:25877594ENST00000398774-1322864_290104516.0RepeatNote=Plectin 2
HgenePLECchr8:145049345chr17:25877594ENST00000398774-1322902_293904516.0RepeatNote=Plectin 3
HgenePLECchr8:145049345chr17:25877594ENST00000398774-1322940_297704516.0RepeatNote=Plectin 4
HgenePLECchr8:145049345chr17:25877594ENST00000398774-1322981_301504516.0RepeatNote=Plectin 5
HgenePLECchr8:145049345chr17:25877594ENST00000398774-1323116_315304516.0RepeatNote=Plectin 6
HgenePLECchr8:145049345chr17:25877594ENST00000398774-1323154_319104516.0RepeatNote=Plectin 7
HgenePLECchr8:145049345chr17:25877594ENST00000398774-1323192_322904516.0RepeatNote=Plectin 8
HgenePLECchr8:145049345chr17:25877594ENST00000398774-1323230_326704516.0RepeatNote=Plectin 9
HgenePLECchr8:145049345chr17:25877594ENST00000398774-1323268_330504516.0RepeatNote=Plectin 10
HgenePLECchr8:145049345chr17:25877594ENST00000398774-1323306_334304516.0RepeatNote=Plectin 11
HgenePLECchr8:145049345chr17:25877594ENST00000398774-1323485_352204516.0RepeatNote=Plectin 12
HgenePLECchr8:145049345chr17:25877594ENST00000398774-1323523_356004516.0RepeatNote=Plectin 13
HgenePLECchr8:145049345chr17:25877594ENST00000398774-1323561_359804516.0RepeatNote=Plectin 14
HgenePLECchr8:145049345chr17:25877594ENST00000398774-1323599_363604516.0RepeatNote=Plectin 15
HgenePLECchr8:145049345chr17:25877594ENST00000398774-1323640_367404516.0RepeatNote=Plectin 16
HgenePLECchr8:145049345chr17:25877594ENST00000398774-1323820_385704516.0RepeatNote=Plectin 17
HgenePLECchr8:145049345chr17:25877594ENST00000398774-1323858_389504516.0RepeatNote=Plectin 18
HgenePLECchr8:145049345chr17:25877594ENST00000398774-1323896_393304516.0RepeatNote=Plectin 19
HgenePLECchr8:145049345chr17:25877594ENST00000398774-1323934_397104516.0RepeatNote=Plectin 20
HgenePLECchr8:145049345chr17:25877594ENST00000398774-1323975_400804516.0RepeatNote=Plectin 21
HgenePLECchr8:145049345chr17:25877594ENST00000398774-1324063_410004516.0RepeatNote=Plectin 22
HgenePLECchr8:145049345chr17:25877594ENST00000398774-1324101_413804516.0RepeatNote=Plectin 23
HgenePLECchr8:145049345chr17:25877594ENST00000398774-1324139_417604516.0RepeatNote=Plectin 24
HgenePLECchr8:145049345chr17:25877594ENST00000398774-1324177_421404516.0RepeatNote=Plectin 25
HgenePLECchr8:145049345chr17:25877594ENST00000398774-1324218_425204516.0RepeatNote=Plectin 26
HgenePLECchr8:145049345chr17:25877594ENST00000398774-1324265_430504516.0RepeatNote=Plectin 27
HgenePLECchr8:145049345chr17:25877594ENST00000398774-1324319_435604516.0RepeatNote=Plectin 28
HgenePLECchr8:145049345chr17:25877594ENST00000398774-1324408_444504516.0RepeatNote=Plectin 29
HgenePLECchr8:145049345chr17:25877594ENST00000398774-1324446_448304516.0RepeatNote=Plectin 30
HgenePLECchr8:145049345chr17:25877594ENST00000398774-1324484_452104516.0RepeatNote=Plectin 31
HgenePLECchr8:145049345chr17:25877594ENST00000398774-1324522_455904516.0RepeatNote=Plectin 32
HgenePLECchr8:145049345chr17:25877594ENST00000398774-1324560_459704516.0RepeatNote=Plectin 33
HgenePLECchr8:145049345chr17:25877594ENST00000398774-132645_71004516.0RepeatNote=Spectrin 1
HgenePLECchr8:145049345chr17:25877594ENST00000398774-132740_82404516.0RepeatNote=Spectrin 2
HgenePLECchr8:145049345chr17:25877594ENST00000398774-132837_93004516.0RepeatNote=Spectrin 3
HgenePLECchr8:145049345chr17:25877594ENST00000436759-2331315_141564.333333333333334575.0RepeatNote=Spectrin 4
HgenePLECchr8:145049345chr17:25877594ENST00000436759-2332826_286364.333333333333334575.0RepeatNote=Plectin 1
HgenePLECchr8:145049345chr17:25877594ENST00000436759-2332864_290164.333333333333334575.0RepeatNote=Plectin 2
HgenePLECchr8:145049345chr17:25877594ENST00000436759-2332902_293964.333333333333334575.0RepeatNote=Plectin 3
HgenePLECchr8:145049345chr17:25877594ENST00000436759-2332940_297764.333333333333334575.0RepeatNote=Plectin 4
HgenePLECchr8:145049345chr17:25877594ENST00000436759-2332981_301564.333333333333334575.0RepeatNote=Plectin 5
HgenePLECchr8:145049345chr17:25877594ENST00000436759-2333116_315364.333333333333334575.0RepeatNote=Plectin 6
HgenePLECchr8:145049345chr17:25877594ENST00000436759-2333154_319164.333333333333334575.0RepeatNote=Plectin 7
HgenePLECchr8:145049345chr17:25877594ENST00000436759-2333192_322964.333333333333334575.0RepeatNote=Plectin 8
HgenePLECchr8:145049345chr17:25877594ENST00000436759-2333230_326764.333333333333334575.0RepeatNote=Plectin 9
HgenePLECchr8:145049345chr17:25877594ENST00000436759-2333268_330564.333333333333334575.0RepeatNote=Plectin 10
HgenePLECchr8:145049345chr17:25877594ENST00000436759-2333306_334364.333333333333334575.0RepeatNote=Plectin 11
HgenePLECchr8:145049345chr17:25877594ENST00000436759-2333485_352264.333333333333334575.0RepeatNote=Plectin 12
HgenePLECchr8:145049345chr17:25877594ENST00000436759-2333523_356064.333333333333334575.0RepeatNote=Plectin 13
HgenePLECchr8:145049345chr17:25877594ENST00000436759-2333561_359864.333333333333334575.0RepeatNote=Plectin 14
HgenePLECchr8:145049345chr17:25877594ENST00000436759-2333599_363664.333333333333334575.0RepeatNote=Plectin 15
HgenePLECchr8:145049345chr17:25877594ENST00000436759-2333640_367464.333333333333334575.0RepeatNote=Plectin 16
HgenePLECchr8:145049345chr17:25877594ENST00000436759-2333820_385764.333333333333334575.0RepeatNote=Plectin 17
HgenePLECchr8:145049345chr17:25877594ENST00000436759-2333858_389564.333333333333334575.0RepeatNote=Plectin 18
HgenePLECchr8:145049345chr17:25877594ENST00000436759-2333896_393364.333333333333334575.0RepeatNote=Plectin 19
HgenePLECchr8:145049345chr17:25877594ENST00000436759-2333934_397164.333333333333334575.0RepeatNote=Plectin 20
HgenePLECchr8:145049345chr17:25877594ENST00000436759-2333975_400864.333333333333334575.0RepeatNote=Plectin 21
HgenePLECchr8:145049345chr17:25877594ENST00000436759-2334063_410064.333333333333334575.0RepeatNote=Plectin 22
HgenePLECchr8:145049345chr17:25877594ENST00000436759-2334101_413864.333333333333334575.0RepeatNote=Plectin 23
HgenePLECchr8:145049345chr17:25877594ENST00000436759-2334139_417664.333333333333334575.0RepeatNote=Plectin 24
HgenePLECchr8:145049345chr17:25877594ENST00000436759-2334177_421464.333333333333334575.0RepeatNote=Plectin 25
HgenePLECchr8:145049345chr17:25877594ENST00000436759-2334218_425264.333333333333334575.0RepeatNote=Plectin 26
HgenePLECchr8:145049345chr17:25877594ENST00000436759-2334265_430564.333333333333334575.0RepeatNote=Plectin 27
HgenePLECchr8:145049345chr17:25877594ENST00000436759-2334319_435664.333333333333334575.0RepeatNote=Plectin 28
HgenePLECchr8:145049345chr17:25877594ENST00000436759-2334408_444564.333333333333334575.0RepeatNote=Plectin 29
HgenePLECchr8:145049345chr17:25877594ENST00000436759-2334446_448364.333333333333334575.0RepeatNote=Plectin 30
HgenePLECchr8:145049345chr17:25877594ENST00000436759-2334484_452164.333333333333334575.0RepeatNote=Plectin 31
HgenePLECchr8:145049345chr17:25877594ENST00000436759-2334522_455964.333333333333334575.0RepeatNote=Plectin 32
HgenePLECchr8:145049345chr17:25877594ENST00000436759-2334560_459764.333333333333334575.0RepeatNote=Plectin 33
HgenePLECchr8:145049345chr17:25877594ENST00000436759-233645_71064.333333333333334575.0RepeatNote=Spectrin 1
HgenePLECchr8:145049345chr17:25877594ENST00000436759-233740_82464.333333333333334575.0RepeatNote=Spectrin 2
HgenePLECchr8:145049345chr17:25877594ENST00000436759-233837_93064.333333333333334575.0RepeatNote=Spectrin 3
HgenePLECchr8:145049345chr17:25877594ENST00000527096-1321315_141564.333333333333334571.0RepeatNote=Spectrin 4
HgenePLECchr8:145049345chr17:25877594ENST00000527096-1322826_286364.333333333333334571.0RepeatNote=Plectin 1
HgenePLECchr8:145049345chr17:25877594ENST00000527096-1322864_290164.333333333333334571.0RepeatNote=Plectin 2
HgenePLECchr8:145049345chr17:25877594ENST00000527096-1322902_293964.333333333333334571.0RepeatNote=Plectin 3
HgenePLECchr8:145049345chr17:25877594ENST00000527096-1322940_297764.333333333333334571.0RepeatNote=Plectin 4
HgenePLECchr8:145049345chr17:25877594ENST00000527096-1322981_301564.333333333333334571.0RepeatNote=Plectin 5
HgenePLECchr8:145049345chr17:25877594ENST00000527096-1323116_315364.333333333333334571.0RepeatNote=Plectin 6
HgenePLECchr8:145049345chr17:25877594ENST00000527096-1323154_319164.333333333333334571.0RepeatNote=Plectin 7
HgenePLECchr8:145049345chr17:25877594ENST00000527096-1323192_322964.333333333333334571.0RepeatNote=Plectin 8
HgenePLECchr8:145049345chr17:25877594ENST00000527096-1323230_326764.333333333333334571.0RepeatNote=Plectin 9
HgenePLECchr8:145049345chr17:25877594ENST00000527096-1323268_330564.333333333333334571.0RepeatNote=Plectin 10
HgenePLECchr8:145049345chr17:25877594ENST00000527096-1323306_334364.333333333333334571.0RepeatNote=Plectin 11
HgenePLECchr8:145049345chr17:25877594ENST00000527096-1323485_352264.333333333333334571.0RepeatNote=Plectin 12
HgenePLECchr8:145049345chr17:25877594ENST00000527096-1323523_356064.333333333333334571.0RepeatNote=Plectin 13
HgenePLECchr8:145049345chr17:25877594ENST00000527096-1323561_359864.333333333333334571.0RepeatNote=Plectin 14
HgenePLECchr8:145049345chr17:25877594ENST00000527096-1323599_363664.333333333333334571.0RepeatNote=Plectin 15
HgenePLECchr8:145049345chr17:25877594ENST00000527096-1323640_367464.333333333333334571.0RepeatNote=Plectin 16
HgenePLECchr8:145049345chr17:25877594ENST00000527096-1323820_385764.333333333333334571.0RepeatNote=Plectin 17
HgenePLECchr8:145049345chr17:25877594ENST00000527096-1323858_389564.333333333333334571.0RepeatNote=Plectin 18
HgenePLECchr8:145049345chr17:25877594ENST00000527096-1323896_393364.333333333333334571.0RepeatNote=Plectin 19
HgenePLECchr8:145049345chr17:25877594ENST00000527096-1323934_397164.333333333333334571.0RepeatNote=Plectin 20
HgenePLECchr8:145049345chr17:25877594ENST00000527096-1323975_400864.333333333333334571.0RepeatNote=Plectin 21
HgenePLECchr8:145049345chr17:25877594ENST00000527096-1324063_410064.333333333333334571.0RepeatNote=Plectin 22
HgenePLECchr8:145049345chr17:25877594ENST00000527096-1324101_413864.333333333333334571.0RepeatNote=Plectin 23
HgenePLECchr8:145049345chr17:25877594ENST00000527096-1324139_417664.333333333333334571.0RepeatNote=Plectin 24
HgenePLECchr8:145049345chr17:25877594ENST00000527096-1324177_421464.333333333333334571.0RepeatNote=Plectin 25
HgenePLECchr8:145049345chr17:25877594ENST00000527096-1324218_425264.333333333333334571.0RepeatNote=Plectin 26
HgenePLECchr8:145049345chr17:25877594ENST00000527096-1324265_430564.333333333333334571.0RepeatNote=Plectin 27
HgenePLECchr8:145049345chr17:25877594ENST00000527096-1324319_435664.333333333333334571.0RepeatNote=Plectin 28
HgenePLECchr8:145049345chr17:25877594ENST00000527096-1324408_444564.333333333333334571.0RepeatNote=Plectin 29
HgenePLECchr8:145049345chr17:25877594ENST00000527096-1324446_448364.333333333333334571.0RepeatNote=Plectin 30
HgenePLECchr8:145049345chr17:25877594ENST00000527096-1324484_452164.333333333333334571.0RepeatNote=Plectin 31
HgenePLECchr8:145049345chr17:25877594ENST00000527096-1324522_455964.333333333333334571.0RepeatNote=Plectin 32
HgenePLECchr8:145049345chr17:25877594ENST00000527096-1324560_459764.333333333333334571.0RepeatNote=Plectin 33
HgenePLECchr8:145049345chr17:25877594ENST00000527096-132645_71064.333333333333334571.0RepeatNote=Spectrin 1
HgenePLECchr8:145049345chr17:25877594ENST00000527096-132740_82464.333333333333334571.0RepeatNote=Spectrin 2
HgenePLECchr8:145049345chr17:25877594ENST00000527096-132837_93064.333333333333334571.0RepeatNote=Spectrin 3


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Fusion Protein-Protein Interaction


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type from validated records (BIOGRID-3.4.160)
GenePPI interactors


check button Protein-protein interactors based on sequence similarity (STRING)
GeneSTRING network
PLEC
KSR1


check button - Retained interactions in fusion protein (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost interactions due to fusion (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs to PLEC-KSR1


check button Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDrugSourcePMID

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Related Diseases to PLEC-KSR1


check button Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDiseaseSourcePMID

check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource