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	Fusion Gene Summary
	Fusion Gene Sample Information
	Fusion ORF Analysis
	Fusion Amino Acid Sequences
	Fusion Protein Functional Features
	Fusion Protein Structure
	pLDDT scores
	Ramachandran Plot of Fusion Protein Structure
	Fusion Protein-Protein Interaction
	Related drugs with this fusion protein
	Related disease with this fusion protein

Fusion Protein:PPP3CA-INTS12

Fusion Protein Summary

Fusion gene summary

Fusion partner gene information	Fusion gene name: PPP3CA-INTS12
	FusionPDB ID: 68119
	FusionGDB2.0 ID: 68119
		Hgene	Tgene
	Gene symbol	PPP3CA	INTS12
	Gene ID	5530	57117
	Gene name	protein phosphatase 3 catalytic subunit alpha	integrator complex subunit 12
	Synonyms	ACCIID\|CALN\|CALNA\|CALNA1\|CCN1\|CNA1\|IECEE\|IECEE1\|PPP2B	INT12\|PHF22\|SBBI22
	Cytomap	4q24	4q24
	Type of gene	protein-coding	protein-coding
	Description	serine/threonine-protein phosphatase 2B catalytic subunit alpha isoformCAM-PRP catalytic subunitcalcineurin A alphacalmodulin-dependent calcineurin A subunit alpha isoformprotein phosphatase 2B, catalytic subunit, alpha isoformprotein phosphatase 3 (	integrator complex subunit 12PHD finger protein 22hypothetical nuclear factor SBBI22
	Modification date	20200315	20200313
	UniProtAcc	.	Q96CB8
Ensembl transtripts involved in fusion gene	ENST ids	ENST00000323055, ENST00000394853, ENST00000394854, ENST00000512215, ENST00000507176, ENST00000510292, ENST00000523694,	ENST00000451321, ENST00000340139, ENST00000394735,
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)	* DoF score	25 X 13 X 8=2600	3 X 2 X 2=12
	# samples	23	2
	** MAII score	log2(23/2600*10)=-3.49880585697144 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(2/12*10)=0.736965594166206 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0
Context (manual curation of fusion genes in FusionPDB)	PubMed: PPP3CA [Title/Abstract] AND INTS12 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)	PPP3CA(102117073)-INTS12(106604474), # samples:3
Anticipated loss of major functional domain due to fusion event.	PPP3CA-INTS12 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. PPP3CA-INTS12 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. PPP3CA-INTS12 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. PPP3CA-INTS12 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. PPP3CA-INTS12 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Hgene	PPP3CA	GO:0006470	protein dephosphorylation	18815128\|19154138
Hgene	PPP3CA	GO:0033173	calcineurin-NFAT signaling cascade	19154138\|22688515
Hgene	PPP3CA	GO:0035690	cellular response to drug	11005320
Hgene	PPP3CA	GO:0045944	positive regulation of transcription by RNA polymerase II	22688515
Hgene	PPP3CA	GO:0051592	response to calcium ion	18815128
Tgene	INTS12	GO:0016180	snRNA processing	16239144

Fusion gene breakpoints across PPP3CA (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across INTS12 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

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Fusion Gene Sample Information

Fusion gene information from FusionGDB2.0.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	PRAD	TCGA-HC-8266-01A	PPP3CA	chr4	102117073	-	INTS12	chr4	106604474	-
ChimerDB4	PRAD	TCGA-HC-8266	PPP3CA	chr4	102117073	-	INTS12	chr4	106604474	-

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Fusion ORF Analysis

Fusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000512215	PPP3CA	chr4	102117073	-	ENST00000394735	INTS12	chr4	106604474	-	1631	940	1550	888	220
ENST00000512215	PPP3CA	chr4	102117073	-	ENST00000340139	INTS12	chr4	106604474	-	1631	940	1550	888	220
ENST00000394854	PPP3CA	chr4	102117073	-	ENST00000394735	INTS12	chr4	106604474	-	1634	943	1553	891	220
ENST00000394854	PPP3CA	chr4	102117073	-	ENST00000340139	INTS12	chr4	106604474	-	1634	943	1553	891	220
ENST00000323055	PPP3CA	chr4	102117073	-	ENST00000394735	INTS12	chr4	106604474	-	1625	934	1544	882	220
ENST00000323055	PPP3CA	chr4	102117073	-	ENST00000340139	INTS12	chr4	106604474	-	1625	934	1544	882	220
ENST00000394853	PPP3CA	chr4	102117073	-	ENST00000394735	INTS12	chr4	106604474	-	1481	790	1400	738	220
ENST00000394853	PPP3CA	chr4	102117073	-	ENST00000340139	INTS12	chr4	106604474	-	1481	790	1400	738	220

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000512215	ENST00000394735	PPP3CA	chr4	102117073	-	INTS12	chr4	106604474	-	0.024850965	0.975149
ENST00000512215	ENST00000340139	PPP3CA	chr4	102117073	-	INTS12	chr4	106604474	-	0.024850965	0.975149
ENST00000394854	ENST00000394735	PPP3CA	chr4	102117073	-	INTS12	chr4	106604474	-	0.027533596	0.9724664
ENST00000394854	ENST00000340139	PPP3CA	chr4	102117073	-	INTS12	chr4	106604474	-	0.027533596	0.9724664
ENST00000323055	ENST00000394735	PPP3CA	chr4	102117073	-	INTS12	chr4	106604474	-	0.02141134	0.9785887
ENST00000323055	ENST00000340139	PPP3CA	chr4	102117073	-	INTS12	chr4	106604474	-	0.02141134	0.9785887
ENST00000394853	ENST00000394735	PPP3CA	chr4	102117073	-	INTS12	chr4	106604474	-	0.027635556	0.97236437
ENST00000394853	ENST00000340139	PPP3CA	chr4	102117073	-	INTS12	chr4	106604474	-	0.027635556	0.97236437

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Fusion Amino Acid Sequences

For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

>68119_68119_1_PPP3CA-INTS12_PPP3CA_chr4_102117073_ENST00000323055_INTS12_chr4_106604474_ENST00000340139_length(amino acids)=220AA_BP=0
MIQKPTWPHYFLSFFWAAFFLTICNRFIALSCDSCEVGPLRDAEGELLDSEVVLLVVLPLGPDVPLFPFPLSWLLLPGTKLLGLGRPTLL
TLSQLTERLRPVLPKVRGGGGFKGTVGVVLLLEPILEPIPPLDDVARPVKPTGFWLADEVAGFPVLFCVVELNFAVEGPAEEVLAAKAAH

--------------------------------------------------------------

>68119_68119_2_PPP3CA-INTS12_PPP3CA_chr4_102117073_ENST00000323055_INTS12_chr4_106604474_ENST00000394735_length(amino acids)=220AA_BP=0
MIQKPTWPHYFLSFFWAAFFLTICNRFIALSCDSCEVGPLRDAEGELLDSEVVLLVVLPLGPDVPLFPFPLSWLLLPGTKLLGLGRPTLL
TLSQLTERLRPVLPKVRGGGGFKGTVGVVLLLEPILEPIPPLDDVARPVKPTGFWLADEVAGFPVLFCVVELNFAVEGPAEEVLAAKAAH

--------------------------------------------------------------

>68119_68119_3_PPP3CA-INTS12_PPP3CA_chr4_102117073_ENST00000394853_INTS12_chr4_106604474_ENST00000340139_length(amino acids)=220AA_BP=0
MIQKPTWPHYFLSFFWAAFFLTICNRFIALSCDSCEVGPLRDAEGELLDSEVVLLVVLPLGPDVPLFPFPLSWLLLPGTKLLGLGRPTLL
TLSQLTERLRPVLPKVRGGGGFKGTVGVVLLLEPILEPIPPLDDVARPVKPTGFWLADEVAGFPVLFCVVELNFAVEGPAEEVLAAKAAH

--------------------------------------------------------------

>68119_68119_4_PPP3CA-INTS12_PPP3CA_chr4_102117073_ENST00000394853_INTS12_chr4_106604474_ENST00000394735_length(amino acids)=220AA_BP=0
MIQKPTWPHYFLSFFWAAFFLTICNRFIALSCDSCEVGPLRDAEGELLDSEVVLLVVLPLGPDVPLFPFPLSWLLLPGTKLLGLGRPTLL
TLSQLTERLRPVLPKVRGGGGFKGTVGVVLLLEPILEPIPPLDDVARPVKPTGFWLADEVAGFPVLFCVVELNFAVEGPAEEVLAAKAAH

--------------------------------------------------------------

>68119_68119_5_PPP3CA-INTS12_PPP3CA_chr4_102117073_ENST00000394854_INTS12_chr4_106604474_ENST00000340139_length(amino acids)=220AA_BP=0
MIQKPTWPHYFLSFFWAAFFLTICNRFIALSCDSCEVGPLRDAEGELLDSEVVLLVVLPLGPDVPLFPFPLSWLLLPGTKLLGLGRPTLL
TLSQLTERLRPVLPKVRGGGGFKGTVGVVLLLEPILEPIPPLDDVARPVKPTGFWLADEVAGFPVLFCVVELNFAVEGPAEEVLAAKAAH

--------------------------------------------------------------

>68119_68119_6_PPP3CA-INTS12_PPP3CA_chr4_102117073_ENST00000394854_INTS12_chr4_106604474_ENST00000394735_length(amino acids)=220AA_BP=0
MIQKPTWPHYFLSFFWAAFFLTICNRFIALSCDSCEVGPLRDAEGELLDSEVVLLVVLPLGPDVPLFPFPLSWLLLPGTKLLGLGRPTLL
TLSQLTERLRPVLPKVRGGGGFKGTVGVVLLLEPILEPIPPLDDVARPVKPTGFWLADEVAGFPVLFCVVELNFAVEGPAEEVLAAKAAH

--------------------------------------------------------------

>68119_68119_7_PPP3CA-INTS12_PPP3CA_chr4_102117073_ENST00000512215_INTS12_chr4_106604474_ENST00000340139_length(amino acids)=220AA_BP=0
MIQKPTWPHYFLSFFWAAFFLTICNRFIALSCDSCEVGPLRDAEGELLDSEVVLLVVLPLGPDVPLFPFPLSWLLLPGTKLLGLGRPTLL
TLSQLTERLRPVLPKVRGGGGFKGTVGVVLLLEPILEPIPPLDDVARPVKPTGFWLADEVAGFPVLFCVVELNFAVEGPAEEVLAAKAAH

--------------------------------------------------------------

>68119_68119_8_PPP3CA-INTS12_PPP3CA_chr4_102117073_ENST00000512215_INTS12_chr4_106604474_ENST00000394735_length(amino acids)=220AA_BP=0
MIQKPTWPHYFLSFFWAAFFLTICNRFIALSCDSCEVGPLRDAEGELLDSEVVLLVVLPLGPDVPLFPFPLSWLLLPGTKLLGLGRPTLL
TLSQLTERLRPVLPKVRGGGGFKGTVGVVLLLEPILEPIPPLDDVARPVKPTGFWLADEVAGFPVLFCVVELNFAVEGPAEEVLAAKAAH

--------------------------------------------------------------

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Fusion Protein Functional Features

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr4:102117073/chr4:106604474)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
.	INTS12 Q96CB8
FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.	FUNCTION: Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (PubMed:16239144). Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex (PubMed:23904267). {ECO:0000269\|PubMed:16239144, ECO:0000269\|PubMed:23904267}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page
* Minus value of BPloci means that the break pointn is located before the CDS.

- Retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Tgene

INTS12

chr4:102117073

chr4:106604474

ENST00000340139

270_440

268.0

463.0

Compositional bias

Note=Ser-rich

Tgene

INTS12

chr4:102117073

chr4:106604474

ENST00000394735

270_440

268.0

463.0

Compositional bias

Note=Ser-rich

Tgene

INTS12

chr4:102117073

chr4:106604474

ENST00000451321

270_440

268.0

463.0

Compositional bias

Note=Ser-rich

- Not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

PPP3CA

chr4:102117073

chr4:106604474

ENST00000323055

307_311

86.33333333333333

470.0

Motif

SAPNY motif

Hgene

PPP3CA

chr4:102117073

chr4:106604474

ENST00000394853

307_311

86.33333333333333

512.0

Motif

SAPNY motif

Hgene

PPP3CA

chr4:102117073

chr4:106604474

ENST00000394854

307_311

86.33333333333333

522.0

Motif

SAPNY motif

Hgene

PPP3CA

chr4:102117073

chr4:106604474

ENST00000512215

307_311

86.33333333333333

290.0

Motif

SAPNY motif

Hgene

PPP3CA

chr4:102117073

chr4:106604474

ENST00000323055

341_369

86.33333333333333

470.0

Region

Calcineurin B binding

Hgene

PPP3CA

chr4:102117073

chr4:106604474

ENST00000323055

392_406

86.33333333333333

470.0

Region

Calmodulin-binding

Hgene

PPP3CA

chr4:102117073

chr4:106604474

ENST00000323055

407_414

86.33333333333333

470.0

Region

Autoinhibitory segment

Hgene

PPP3CA

chr4:102117073

chr4:106604474

ENST00000323055

465_487

86.33333333333333

470.0

Region

Autoinhibitory domain

Hgene

PPP3CA

chr4:102117073

chr4:106604474

ENST00000323055

56_340

86.33333333333333

470.0

Region

Catalytic

Hgene

PPP3CA

chr4:102117073

chr4:106604474

ENST00000394853

341_369

86.33333333333333

512.0

Region

Calcineurin B binding

Hgene

PPP3CA

chr4:102117073

chr4:106604474

ENST00000394853

392_406

86.33333333333333

512.0

Region

Calmodulin-binding

Hgene

PPP3CA

chr4:102117073

chr4:106604474

ENST00000394853

407_414

86.33333333333333

512.0

Region

Autoinhibitory segment

Hgene

PPP3CA

chr4:102117073

chr4:106604474

ENST00000394853

465_487

86.33333333333333

512.0

Region

Autoinhibitory domain

Hgene

PPP3CA

chr4:102117073

chr4:106604474

ENST00000394853

56_340

86.33333333333333

512.0

Region

Catalytic

Hgene

PPP3CA

chr4:102117073

chr4:106604474

ENST00000394854

341_369

86.33333333333333

522.0

Region

Calcineurin B binding

Hgene

PPP3CA

chr4:102117073

chr4:106604474

ENST00000394854

392_406

86.33333333333333

522.0

Region

Calmodulin-binding

Hgene

PPP3CA

chr4:102117073

chr4:106604474

ENST00000394854

407_414

86.33333333333333

522.0

Region

Autoinhibitory segment

Hgene

PPP3CA

chr4:102117073

chr4:106604474

ENST00000394854

465_487

86.33333333333333

522.0

Region

Autoinhibitory domain

Hgene

PPP3CA

chr4:102117073

chr4:106604474

ENST00000394854

56_340

86.33333333333333

522.0

Region

Catalytic

Hgene

PPP3CA

chr4:102117073

chr4:106604474

ENST00000512215

341_369

86.33333333333333

290.0

Region

Calcineurin B binding

Hgene

PPP3CA

chr4:102117073

chr4:106604474

ENST00000512215

392_406

86.33333333333333

290.0

Region

Calmodulin-binding

Hgene

PPP3CA

chr4:102117073

chr4:106604474

ENST00000512215

407_414

86.33333333333333

290.0

Region

Autoinhibitory segment

Hgene

PPP3CA

chr4:102117073

chr4:106604474

ENST00000512215

465_487

86.33333333333333

290.0

Region

Autoinhibitory domain

Hgene

PPP3CA

chr4:102117073

chr4:106604474

ENST00000512215

56_340

86.33333333333333

290.0

Region

Catalytic

Tgene

INTS12

chr4:102117073

chr4:106604474

ENST00000340139

159_215

268.0

463.0

Zinc finger

PHD-type

Tgene

INTS12

chr4:102117073

chr4:106604474

ENST00000394735

159_215

268.0

463.0

Zinc finger

PHD-type

Tgene

INTS12

chr4:102117073

chr4:106604474

ENST00000451321

159_215

268.0

463.0

Zinc finger

PHD-type

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Fusion Protein Structures

PDB and CIF files of the predicted fusion proteins
* Here we show the 3D structure of the fusion proteins using Mol*. AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Model confidence is shown from the pLDDT values per residue. pLDDT corresponds to the model’s prediction of its score on the local Distance Difference Test. It is a measure of local accuracy (from AlphfaFold website). To color code individual residues, we transformed individual PDB files into CIF format.

Fusion protein PDB link (fusion AA seq ID in FusionPDB)	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	AA seq	Len(AA seq)
PDB file >>>327_PPP3CA_102117073_INTS12_106604474_ranked_0.pdb	PPP3CA	102117073	102117073	ENST00000340139	INTS12	chr4	106604474	-	MIQKPTWPHYFLSFFWAAFFLTICNRFIALSCDSCEVGPLRDAEGELLDSEVVLLVVLPLGPDVPLFPFPLSWLLLPGTKLLGLGRPTLL TLSQLTERLRPVLPKVRGGGGFKGTVGVVLLLEPILEPIPPLDDVARPVKPTGFWLADEVAGFPVLFCVVELNFAVEGPAEEVLAAKAAH	220

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pLDDT score distribution

pLDDT score distribution of the predicted wild-type structures of two partner proteins from AlphaFold2
* AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100.

PPP3CA_pLDDT.png

INTS12_pLDDT.png

pLDDT score distribution of the predicted fusion protein structures from AlphaFold2
* AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100.

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Ramachandran Plot of Fusion Protein Structure

Ramachandran plot of the torsional angles - phi (φ)and psi (ψ) - of the residues (amino acids) contained in this fusion protein peptide.

Fusion AA seq ID in FusionPDB and their Ramachandran plots

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Fusion Protein-Protein Interaction

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type from validated records (BIOGRID-3.4.160)

Gene

PPI interactors

Protein-protein interactors based on sequence similarity (STRING)

Gene	STRING network
PPP3CA
INTS12

- Retained interactions in fusion protein (protein functional feature from UniProt).

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost interactions due to fusion (protein functional feature from UniProt).

Partner	Gene	Hbp	Tbp	ENST	Strand	BPexon	TotalExon	Protein feature loci	*BPloci	TotalLen	Interaction lost with
Hgene	PPP3CA	chr4:102117073	chr4:106604474	ENST00000323055	-	2	12	327_336	86.33333333333333	470.0	PxIxIF motif in substrate
Hgene	PPP3CA	chr4:102117073	chr4:106604474	ENST00000394853	-	2	13	327_336	86.33333333333333	512.0	PxIxIF motif in substrate
Hgene	PPP3CA	chr4:102117073	chr4:106604474	ENST00000394854	-	2	14	327_336	86.33333333333333	522.0	PxIxIF motif in substrate
Hgene	PPP3CA	chr4:102117073	chr4:106604474	ENST00000512215	-	2	8	327_336	86.33333333333333	290.0	PxIxIF motif in substrate

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Related Drugs to PPP3CA-INTS12

Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)

Hgene

Tgene

Drug

Source

PMID

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Related Diseases to PPP3CA-INTS12

Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)

Hgene

Tgene

Disease

Source

PMID

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source